27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
Dementia-friendly designs are important in residential care homes but an aspect that remains neglected is the potential role of door designs in promoting wayfinding. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Dementia, especially Alzheimer’s disease, is increasing due to population ageing and is projected to nearly triple by 2050. 2 key findings →
Participants: 46 Evidence: low
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Studies are heterogeneous in many aspects, including size sample, intervention, and instruments of measures. 3 key findings →
Design: systematic review Participants: 20 Evidence: high
Full summary, score breakdown and related studies → Original source
This pilot study aimed to compare the effect of companion robots (PARO) to participation in an interactive reading group on emotions in people living with moderate to severe dementia in a residential care setting. 2 key findings →
Evidence: high
Full summary, score breakdown and related studies → Original source
Targeted clinical application of specific technologies is poised to revolutionize precision care in dementia as these technologies may be used both by patients and caregivers, and at a systems level to provide safe and effective care. 2 key findings →
Design: systematic review Participants: 1,337 Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
These studies show that remote physical activity monitoring is feasible in neurological diseases, including in people with moderate to severe neurological disability. 3 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
Behavioural and psychological symptoms of dementia affect nearly all people with dementia. 1 key finding →
Design: longitudinal study Participants: 587 Evidence: moderate
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Many older people's crisis teams tend to focus on prevention and reducing psychiatric admissions. 3 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
Short-term mortality is increased in patients newly diagnosed with probable AD. 5 key findings →
Design: longitudinal study Participants: 327 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Behavioral and psychological symptoms of dementia include agitation, depression, apathy, repetitive questioning, psychosis, aggression, sleep problems, wandering, and a variety of inappropriate behaviors. 5 key findings →
Evidence: low
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Increased BPSD was reported in 59.6% of patients as worsening of preexisting symptoms (51.9%) or as new onset (26%), and requested drug modifications in 27.6% of these cases. 4 key findings →
Participants: 4,913 Evidence: low
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Behavioral symptoms such as repetitive speech, wandering, and sleep disturbances are a core clinical feature of Alzheimer disease and related dementias. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Our model could aid GPs or health service planners with the early detection of dementia. 1 key finding →
Design: case-control study Participants: 93,120 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
PLWD also commonly experience social isolation (Shen et al., 2022), poorer physical function (Jehu et al., 2024a), worsened behavioral and psychological symptoms (Cerejeira et al., 2012), poorer quality of life (Cerejeira et al., 2012), and reduced access to healthcare (Mitchell et al., 2016) compared to older adults without dementia. 5 key findings →
Design: randomized controlled trial Participants: 21 Evidence: high
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The built environment has direct and indirect effects on mental health. 1 key finding →
Design: longitudinal study Evidence: high
Full summary, score breakdown and related studies → Original source
Misidentification, wandering or agitation, and physical aggression increased during follow-up. 5 key findings →
Design: longitudinal study Evidence: moderate
Full summary, score breakdown and related studies → Original source
This cross-sectional study examines relationships among the constellation of psychiatric syndromes in Alzheimer's disease (AD) as a function of dementia severity in 1155 patients with probable AD. 4 key findings →
Design: cross-sectional Participants: 1,155 Evidence: low
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The prevention of fall-related injuries in patients with Alzheimer-type dementia (ATD) is hampered by an incomplete understanding of their causes. 5 key findings →
Evidence: low
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Disruptive behavior is very common in AD and predicts cognitive decline, functional decline, and institutionalization but not mortality. 3 key findings →
Participants: 3,438 Evidence: moderate
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Alzheimer disease (AD) is associated with cognitive decline and increased incidence of seizures. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
A strategy of targeting type-specific BPSD may be beneficial, such as environmental stimulus control for DLB patients who are prone to have hallucinations, design of a pacing path for patients with FTD who need support for symptoms of wandering and emotional support for patients with VaD who are susceptible to depression. 1 key finding →
Participants: 137 Evidence: low
Full summary, score breakdown and related studies → Original source
These findings indicate that the use of antipsychotic agents and sedatives can affect the natural course of Alzheimer disease. 5 key findings →
Design: cross-sectional Evidence: moderate
Full summary, score breakdown and related studies → Original source
Circadian rhythms in elderly patients with severe dementia and behavioral disorders such as wandering, agitation and/or delirium were examined. 1 key finding →
Participants: 24 Evidence: low
Full summary, score breakdown and related studies → Original source
Behavioral problems are thought to be pervasive and devastating to patients with dementia of the Alzheimer's type and their families. 4 key findings →
Participants: 127 Evidence: low
Full summary, score breakdown and related studies → Original source
Out of a sample of 178 patients with AD, aggression was present in 20%, wandering in 19%, binge-eating in 10%, hyperorality in 6%, urinary incontinence in 48%, and sexual disinhibition in 7%. 5 key findings →
Participants: 178 Evidence: low
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →