Numerous reports have linked extremity muscle strength with mortality but the mechanism underlying this association is not known. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Research
28,180 Alzheimer's and dementia studies in plain English, each scored out of 100.
Application of predetermined quality criteria for prevalence and outcome studies. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Patients with dementia develop dysphagia some time during the clinical course of their disease. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The demonstration that isoflurane contributes to well-described mechanisms of Alzheimer's neuropathogenesis provides a plausible link between the acute effects of anesthesia, a well-described risk factor for delirium, and the more long-term sequelae of dementia. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The present study examined the relationship between visual attention measures and driving performance in healthy older adults and individuals with very mild and mild dementia of the Alzheimer type (DAT). 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Delirium is a frequent neurocognitive complication in patients with cancer, particularly in patients with advanced-stage disease (in whom a combination of factors might trigger an episode) and in patients with a high degree of predisposing vulnerability, such as the elderly or patients with dementia. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
36/100
Falls are common events in the elderly and represent the main risk factor for fractures and other injuries. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Medical conditions overall, do impact the fitness to drive of older drivers; however, the crash risk tends to be only slightly to moderately increased. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Opinion statement Parkinson's disease (PD) has been increasingly recognized as having a multitude of nonmotor symptoms including psychosis, cognitive impairment and dementia, mood disturbances, fatigue, apathy, and sleep disorders. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The contribution of specific psychotropic drugs to fall risk in patients with dementia has not been quantified precisely until now. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
36/100
Average life expectancy throughout developed countries has rapidly increased during the latter half of the 20th century and geriatric infectious diseases have become an increasingly important issue. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Amyotrophic lateral sclerosis (ALS), first described by Jean-Martin Charcot in the 1870s, is an age-related disorder that leads to degeneration of motor neurons. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Systematic evaluation of end-of-life care in dementia has been hampered by a lack of instruments to specifically address those issues that are unique for persons who are dying with dementia. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Five themes were identified that describe the context of decision making: emotional effect, insult-to-life story, two faces of death, values and goals regarding end-of-life treatments, and the unrecognized trajectory of dying. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
The current evidence base for ACP in dementia is limited. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Instances of futile care evoke strong emotional responses from nurses, and nurses require support in dealing with their distress. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Research on end-of-life care for people with dementia has yet to develop interventions that address the particular challenges that dying with dementia poses. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Our hospice enrollment criteria identified a group with a median survival time of 4 months and a mean survival time of 6.9 months. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Until relatively recently, most psychologists have had limited professional involvement with older adults. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The number of people with dementia will rise dramatically over the next 20 years. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The number of older adults with cognitive impairment is increasing, and such adults often require a surrogate to make decisions about health care. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Professional and family members of demented individuals, especially if they have experience in terminal care decisions, strongly favor palliative care for end-stage dementia. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The 21 conditions selected as targets for quality improvement among vulnerable older adults include (in rank order): pharmacologic management; depression; dementia; heart failure; stroke (and atrial fibrillation); hospitalization and surgery; falls and mobility disorders; diabetes mellitus; end-of-life care; ischemic heart disease; hypertension; pressure ulcers; osteoporosis; urinary incontinence; pain management; preventive services; hearing impairment; pneumonia and influenza; vision impairment; malnutrition; and osteoarthritis. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
This article reports the findings of a policy survey designed to establish research priorities to inform future research strategy and advance nursing home practice. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The quality of end-of-life care exists on a continuum across care settings. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Where “Free full text” comes from
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
How the 0–100 score works — and why some entries are capped
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
- Journal tier up to 10 pts
- Journal's citation record up to 4 pts
- Study design up to 12 pts
- Strength of evidence up to 5 pts
- Peer-review validation up to 10 pts
- How recent up to 5 pts
- Sample size up to 4 pts
- Effect reported up to 3 pts
- Studied in people up to 3 pts
- Randomised / blinded up to 2 pts
- Times cited up to 7 pts
- Citations per year up to 5 pts
- Impact for its field and year up to 6 pts
- Cited by studies here up to 6 pts
- Still being cited up to 4 pts
- Senior author's track record up to 4 pts
- Institution's track record up to 3 pts
- Multi-centre collaboration up to 3 pts
- Indexed in PubMed up to 2 pts
- Free to read up to 2 pts
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 28,180 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
What this library is — and isn't
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 28,180 records, built mostly from automated pulls of Europe PMC (61.7% of the library) and OpenAlex (18.1%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →