28,180 Alzheimer's and dementia studies in plain English, each scored out of 100.
IT WAS the 'gradual realisation' that what he had been taught about dementiain his nurse and social work training was simply 'not helpful' that prompted Colm Cunningham's interest in dementia research, he says. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Close to two-thirds of all US nursing home residents have some type of cognitive impairment such as Alzheimer's disease, and the quality of care and quality of life of these people has long been called into question. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Currently, the Agency for Healthcare Research and Quality (AHRQ) Common Format for nursing homes (NHs) accommodates voluntary reporting for 4 adverse events: falls with injury, pressure ulcers, medication errors, and infections. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Palliative care is mostly restricted to the terminal phase of incurable illness. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
To better understand the process and outcomes of family involvement for long-term care residents with varying stages of dementia, we analyzed family and staff data for 467 residents of 24 residential care/assisted living and nursing-home settings. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
This article describes the prevalence, assessment, and treatment of, as well as characteristics associated with, mobility limitation in 343 residents with dementia in 45 assisted living facilities and nursing homes. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Older adults' sexuality and sexual expression are often overlooked in nursing home and residential care settings. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Over the past two decades the collaborative care model within primary care has proved to be effective in improving care quality, efficiency, and outcomes for older adults suffering from dementia and depression. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
over 90% of the homes had high quality scores on at least two measures. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Three types of communication were identified: staff to staff, staff to resident, and staff to family. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Dementia is a life-limiting disease without curative treatments but the data suggest that advanced dementia is not viewed as a terminal diagnosis by physicians. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Advance care planning is the basis for delivering person-centred end of life care that accords with the wishes of the individual. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Dementia is a life-limiting condition that is largely a disease of ageing. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
This paper will highlight some of the pertinent issues associated with palliative and end-of-life decision-making in relation to dementia. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Although 80% of the deaths worldwide occur in middle- and low-income countries such as India, there is less awareness of end-of-life care (EOLC) for people with chronic, serious, progressive, or advanced life-limiting illnesses, including dementia. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
This article, the second of two, provides healthcare practitioners with an overview of best practice in palliative and end-of-life care, including nutrition, hydration, oral hygiene and pain management. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Since the Liverpool Care Pathway has been withdrawn in the UK, clinicians supporting the palliative needs of patients have faced further challenges, particularly for patients with dementia who are unable to go to a hospice owing to challenging behaviours. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Hospice use over 2 weeks was associated with decreased hospital days (1-5 days overall, with greater decreases for longer hospice use) for all beneficiaries; spending was $900-$5,000 less for hospice use of 31-90 days for most beneficiaries not in nursing homes, except beneficiaries with Alzheimer's. Overall spending decreased with hospice use for beneficiaries in nursing homes with lung cancer only, with a $3,500 reduction. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Racial and ethnic minorities currently comprise 20% of the U.S. population; in 2050, this figure is expected to rise to 42%. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Adjunctive florbetapir-PET increased quality-adjusted life years (QALYs) by 0.008 years and increased costs by 36 compared to SCE alone (incremental cost-effectiveness ratio [ICER], 4,769). 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Care of dementia is extremely resource demanding and has a great impact on both the formal care systems and the situation for informal carers. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Average annual cost among patients diagnosed with dementia was €43,259, primarily incurred by accommodation. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
A study of 127 informal caregivers of Alzheimer's disease patients in Florida's Tampa Bay area was undertaken to determine the correlates of the five components of burden, as measured by the Cost of Care Index, a multidimensional measure of caregiving burden. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Utilizing β-amyloid precursor protein (βAPP) as a substrate, α-, β-, and γ-secretases are responsible for sequential cleavage events leading to the formation of β-amyloid, the classic pathologic hallmark of Alzheimer’s Disease. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Redox degenerative reactions of the biological system inevitably produce reactive oxygen species (ROS) and their derivatives. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 28,180 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 28,180 records, built mostly from automated pulls of Europe PMC (61.7% of the library) and OpenAlex (18.1%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →