39/100
Protein homeostasis, or proteostasis, has an important regulatory role in cellular function. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Research
28,180 Alzheimer's and dementia studies in plain English, each scored out of 100.
Over the past two decades, caregiver stress has been the subject of scientific inquiry by investigators around the world representing a variety of disciplines. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
39/100
Despite the progress made in the understanding of the etiology, neuropathophysiology, and treatment of different types of dementia, such disorders continue to pose huge health problems worldwide. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Liu et al. (2017) investigated caregiver burden of patients with frontotemporal lobar degeneration (FTD) and dementia with Lewy bodies (DLB), which was compared with caregivers of patients with Alzheimer's disease. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The concept of personhood developed by Tom Kitwood highlights that the experience of dementia has relational dimensions that transcend the neurodegenerative impacts of the condition. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Perceived burden was directly and significantly related to depression for both spouse caregivers and adult child caregivers. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Content analysis of the video-recorded group interactions yielded recurrent themes of caregivers' spiritual reflections and their associations with managing caregiver stress responses. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Post-diagnostic care in young-onset dementia (YoD) varies, from something that is occasionally structured, to improvised, to frequently non-existent depending on geographic region. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Phases 1 and 2 results facilitated targeted changes in BESI, thus improving its overall usability for the final phase of the study, when real-time notifications and interventions will be implemented. 2 key findings →
Design: clinical trial Evidence: low
Full summary, score breakdown and related studies → Original source
We provide a review of the current literature and discuss our own care practices. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The purpose of this study was to identify family caregivers' experiences in managing the behavioral and psychological symptoms of dementia (BPSD) with particular focus on their interpersonal interactions with patient with dementia. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Four themes were identified: (a) changing with age, (b) independence and autonomy, (c) bounded identity, and (d) social comparison. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Participants found nursing home care challenging, particularly for patients who were nonverbal due to advanced dementia, because they had difficulties forming meaningful relationships or discussing medical decisions with their patients. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Twenty-four staff members completed the survey and reported positive perspectives about the training, use of the program, and benefits for PWD and themselves. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The coronavirus disease (COVID-19) pandemic has been particularly challenging for nursing home staff and residents. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
As the United States population ages, a higher share of adults is likely to use long-term services and supports. 5 key findings →
Design: narrative review Evidence: low
Full summary, score breakdown and related studies → Original source
Despite a formal inpatient or outpatient classification, the residents living in AL facilities showed significantly higher values for well-being and showed significantly less agitated, challenging behavior compared to the nursing home. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Sixteen states license or certify dementia care units within RC/AL settings. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Data were analysed using thematic analysis. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
AimTo explore the experiences and challenges for residential care home staff when managing the healthcare needs of their residents, in particular those living with dementia. 1 key finding →
Design: clinical trial Evidence: low
Full summary, score breakdown and related studies → Original source
Using qualitative interviews, this research explores the experiences of residential nursing home caregivers in Fukushima, who provided support to elderly sufferers of Alzheimer's or other related forms of dementia during the 2011 Great East Japan Earthquake and Tsunami. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Alternative care environments for regular nursing homes are highly warranted to promote health and well-being of residents with dementia that are part of an age-friendly and dementia-friendly city and society. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
39/100
A one percentage point reduction in elderspeak costs $6.75 per staff member with average baseline elderspeak usage. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
39/100
Dementia will become more common as the population ages. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
39/100
In this narrative, a third-year medical student recounts an experience with a patient she had while accompanying hospice and palliative workers on home visits. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Where “Free full text” comes from
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
How the 0–100 score works — and why some entries are capped
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
- Journal tier up to 10 pts
- Journal's citation record up to 4 pts
- Study design up to 12 pts
- Strength of evidence up to 5 pts
- Peer-review validation up to 10 pts
- How recent up to 5 pts
- Sample size up to 4 pts
- Effect reported up to 3 pts
- Studied in people up to 3 pts
- Randomised / blinded up to 2 pts
- Times cited up to 7 pts
- Citations per year up to 5 pts
- Impact for its field and year up to 6 pts
- Cited by studies here up to 6 pts
- Still being cited up to 4 pts
- Senior author's track record up to 4 pts
- Institution's track record up to 3 pts
- Multi-centre collaboration up to 3 pts
- Indexed in PubMed up to 2 pts
- Free to read up to 2 pts
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 28,180 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
What this library is — and isn't
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 28,180 records, built mostly from automated pulls of Europe PMC (61.7% of the library) and OpenAlex (18.1%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →