28,580 Alzheimer's and dementia studies in plain English, each scored out of 100.
All patients underwent MRI and β-amyloid biomarker testing via 11 C-PiB or cerebrospinal fluid. 18 F-flortaucipir uptake in patients was compared to 53 β-amyloid negative normal controls using voxelwise and pre-specified region of interest approaches. 5 key findings →
Participants: 45 Evidence: low
Full summary, score breakdown and related studies → Original source
High peripheral AGE level is associated with greater cognitive decline in older adults with and without diabetes. 5 key findings →
Participants: 920 Evidence: low
Full summary, score breakdown and related studies → Original source
We investigated the incidence and extent of Lewy body (LB)-related alpha-synucleinopathy (LBAS) in the olfactory bulb (OB) in 320 consecutive autopsy patients from a general geriatric hospital (mean age, 81.5 +/- 8.5 years). 1 key finding →
Participants: 102 Evidence: low
Full summary, score breakdown and related studies → Original source
Early-phase FBB acquisitions correlate on a relative quantitative and visual level with FDG PET scans, irrespective of the amyloid plaque density assessed in late FBB imaging. 3 key findings →
Participants: 33 Evidence: low
Full summary, score breakdown and related studies → Original source
Physical as well as cognitive training interventions improve specific cognitive functions but effects barely generalize on global cognition. 4 key findings →
Participants: 237 Evidence: low
Full summary, score breakdown and related studies → Original source
We found no strong associations with development of cognitive dysfunction for any of the dietary patterns investigated. 4 key findings →
Participants: 564 Evidence: moderate
Full summary, score breakdown and related studies → Original source
These results suggest pairing tDCS with cognitive training enhances functional connectivity and working memory performance in older adults, and thus may hold promise as a method for remediating age-related cognitive decline. 3 key findings →
Participants: 28 Evidence: low
Full summary, score breakdown and related studies → Original source
The results also suggest that grammatical reasoning and episodic memory should be targeted in developing appropriate outcome measures to assess efficacy of future interventions, and in developing cognitive training programmes to prevent or delay cognitive decline. 5 key findings →
Participants: 65,000 Evidence: low
Full summary, score breakdown and related studies → Original source
Prospective studies are needed to validate current findings. 4 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
Along with rapid global population aging, the age-related cognitive disorders such as mild cognitive impairment (MCI) and dementia have posed a serious threat to public health, health care system, and sustainable economic and societal development of all countries. 1 key finding →
Design: narrative review Evidence: high
Full summary, score breakdown and related studies → Original source
However, the brain plasticity associated with these proposed benefits of combined therapy has not yet been investigated in elderly subjects. 5 key findings →
Participants: 61 Evidence: low
Full summary, score breakdown and related studies → Original source
Overall, enjoyment and acceptance of casual game characteristics was high and significantly above the midpoint of the rating scale for all CVG genres. 5 key findings →
Participants: 16 Evidence: low
Full summary, score breakdown and related studies → Original source
Older adults with mild dementia demonstrated worse baseline cognitive performance than participants without dementia. 4 key findings →
Participants: 72 Evidence: low
Full summary, score breakdown and related studies → Original source
The present work contributes to the literature on ICT usability needs of users with MCI. 3 key findings →
Participants: 28 Evidence: low
Full summary, score breakdown and related studies → Original source
Early and accurate diagnosis of MCI provides a window of opportunity to improve the outcomes using a multimodal management approach including lifestyle risk factor modification and consideration of the multinutrient Souvenaid. 1 key finding →
Evidence: high
Full summary, score breakdown and related studies → Original source
Cognitive decline after surgery is biphasic and accelerated among persons with delirium. 1 key finding →
Participants: 560 Evidence: low
Full summary, score breakdown and related studies → Original source
Comanagement by geriatricians and orthopedic surgeons, combined with standardized care, leads to improved processes and outcomes for patients with hip fractures. 4 key findings →
Participants: 193 Evidence: low
Full summary, score breakdown and related studies → Original source
The low likelihood of patients with cAF in general practice remaining on treatment long-term indicates that not all benefits as observed in clinical trials may be achieved in usual clinical practice. 4 key findings →
Participants: 41 Evidence: low
Full summary, score breakdown and related studies → Original source
Delirium is highly prevalent among persons with AD who are hospitalized and is associated with an increased rate of cognitive deterioration that is maintained for up to 5 years. 5 key findings →
Participants: 263 Evidence: moderate
Full summary, score breakdown and related studies → Original source
A lower number of teeth are positively related to swallowing dysfunction, whereas denture wearing contributes to recovery of swallowing function. 3 key findings →
Participants: 286 Evidence: low
Full summary, score breakdown and related studies → Original source
Although their prognosis is worse, even the oldest and most severely frail patients may benefit from hospitalization for COVID-19, if sufficient resources are available. 5 key findings →
Participants: 48 Evidence: low
Full summary, score breakdown and related studies → Original source
Dysphagia is a major health care problem in nursing homes. 2 key findings →
Participants: 395 Evidence: low
Full summary, score breakdown and related studies → Original source
This study confirms previous reports of potentially hazardous driving in persons with early Alzheimer disease, but also indicates that some individuals with very mild dementia can continue to drive safely for extended periods of time. 3 key findings →
Participants: 128 Evidence: low
Full summary, score breakdown and related studies → Original source
Dementia and delirium were prevalent, yet under-recognized, in acute medical geriatric inpatients. 3 key findings →
Participants: 144 Evidence: low
Full summary, score breakdown and related studies → Original source
Our aim was to investigate the long-term prognosis of delirium in the frailest elderly, and to clarify whether delirium is just a marker of the underlying severe disease. 5 key findings →
Participants: 425 Evidence: low
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 28,580 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 28,580 records, built mostly from automated pulls of Europe PMC (62.2% of the library) and OpenAlex (17.8%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.6% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →