28,180 Alzheimer's and dementia studies in plain English, each scored out of 100.
Transcranial direct current stimulation (tDCS) is a technique of noninvasive cortical stimulation allowing significant modification of brain functions. 2 key findings →
Design: meta-analysis Evidence: high
Full summary, score breakdown and related studies → Original source
Many older people's crisis teams tend to focus on prevention and reducing psychiatric admissions. 3 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
This review shows that occupational therapy interventions for community dwelling elderly people results in positive outcomes. 2 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
Forty-two case-control, cohort, and randomized trials were identified and included in the review. 3 key findings →
Design: randomized controlled trial Evidence: high
Full summary, score breakdown and related studies → Original source
Drivers with dementia are poorer drivers than cognitively normal drivers, but studies have not consistently demonstrated higher crash rates. 3 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
Men are at higher risk of postoperative delirium after hip fracture repair than women and have more postoperative surgical complications. 5 key findings →
Design: cohort study Participants: 431 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Without validated cutoff scores, it is impossible to employ tests in a standardized fashion in front-line clinical settings. 1 key finding →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
SSD in older people may be a frequent and clinically important condition that falls on a continuum between no symptoms and full delirium. 3 key findings →
Design: meta-analysis Evidence: high
Full summary, score breakdown and related studies → Original source
This review found significant variation among the cost estimates and methodological quality. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
In this study, patients with advanced dementia and hip fracture or pneumonia had a very poor prognosis. 3 key findings →
Design: cohort study Participants: 59 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Whilst palliative care is appropriate for elderly patients with chronic, non-malignant disease, few of these patients access such care compared with cancer patients. 2 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
Our aim was to review systematically the effectiveness of ACP interventions in people with cognitive impairment and dementia. 2 key findings →
Design: meta-analysis Evidence: high
Full summary, score breakdown and related studies → Original source
Palliative care improves cancer, CHF, COPD, and dementia outcomes. 2 key findings →
Evidence: high
Full summary, score breakdown and related studies → Original source
Gatekeeping is motivated by the general assumption of vulnerability of patients, coupled with an emphasis on the duty to protect patients. 1 key finding →
Design: meta-analysis Evidence: high
Full summary, score breakdown and related studies → Original source
Despite the increased interest in palliative care for patients with dementia there is currently little evidence on which to base such an approach. 1 key finding →
Design: randomized controlled trial Evidence: high
Full summary, score breakdown and related studies → Original source
We recommend development and testing of decision aids targeting the decisions carers report finding most distressing, including those around where people should live, accessing services, and end of life treatments. 2 key findings →
Evidence: high
Full summary, score breakdown and related studies → Original source
There is need for clearer articulation of the likely mechanisms by which advance care planning can lead to reduced care costs or improved cost-effectiveness, particularly for people who retain capacity. 3 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
Questionably beneficial medications are common in advanced dementia, even as death approaches. 5 key findings →
Design: cohort study Participants: 323 Evidence: moderate
Full summary, score breakdown and related studies → Original source
The BFC80+ was designed to acquire a better understanding of the epidemiology and pathophysiology of chronic diseases in the very elderly and to study the dynamic interaction between health, frailty and disability in a multi-system approach. 5 key findings →
Design: cohort study Participants: 567 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Despite much data, we lack a unifying guideline for dementia prognostication. 1 key finding →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
Three-year survival after dementia diagnosis can be predicted with good accuracy. 1 key finding →
Participants: 50,076 Evidence: moderate
Full summary, score breakdown and related studies → Original source
The aim of this study was to undertake a systematic review and narrative synthesis of the literature concerning place of death of people with dementia and the preferences for location of death of people with dementia as well as family carers and healthcare providers preferred location of death for patients with dementia. 1 key finding →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
APOE ε4 count was associated with higher TDP-43 proteinopathy stage (odds ratio [OR] 2·0, 95% CI 1·6-2·6; p=1·9 × 10 -9 ) and TDP-43 burden (0·40, 0·28-0·52; p=1·2 × 10 -10 ). 3 key findings →
Design: cohort study Participants: 15 Evidence: moderate
Full summary, score breakdown and related studies → Original source
The combinations of pathologies of Alzheimer's disease and related dementias associated with cognitive and motor decline and their onsets of associations varied; only tau tangles, Parkinson's disease pathology, and macroinfarcts were associated with decline of all three phenotypes. 5 key findings →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source
Caring for people with dementia in primary care demands the same systematic approach as the management of other long-term conditions. 1 key finding →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 28,180 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 28,180 records, built mostly from automated pulls of Europe PMC (61.7% of the library) and OpenAlex (18.1%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →