28,180 Alzheimer's and dementia studies in plain English, each scored out of 100.
Beyond the well-known effects on cognitive impairment of the Mediterranean diet, a number of studies have investigated the possible action on cognitive decline of different botanicals and phytochemicals, most of which are well-known anti-inflammatory or antioxidant agents with a good tolerability and safety profile. 5 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
The present meta-analysis revealed a significant effect for computer-based cognitive training on the performance of the memory domain of patients with MS. This finding may have significant implications in the current treatment practice when cognitive decline is detected in MS patients. 5 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
The purpose of the present study was to explore the effects of computer-based multidomain cognitive training program on Greek patients with Mild Cognitive Impairment (MCI). 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Of 6,379 citations, 36 articles met inclusion criteria. 2 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
Among frail older persons, cognitive training conferred the greatest cognitive benefits. 3 key findings →
Participants: 49 Evidence: low
Full summary, score breakdown and related studies → Original source
Studies suggest that n-3 fatty acids in the diet and adherence to the MedDiet are beneficial in slowing age-related cognitive decline. 5 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
The causes of late onset Alzheimer disease (LOAD) are not known but several recent lines of evidence implicate the adaptive immune system. 3 key findings →
Design: longitudinal study Participants: 72 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Our review suggests that MNPIs may improve the global, executive function and memory of PWD in NHs. 2 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
Overall, the psychological intervention and cognitive training may be beneficial to cognitive function and psychological well-being. 4 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
In this study, we explored whether several individual self-reported health behaviors were associated with cognitive decline when considered simultaneously, using data from the Wisconsin Registry for Alzheimer's Prevention (WRAP), an Alzheimer's disease risk-enriched cohort who were non-demented and in late midlife at baseline. 5 key findings →
Design: longitudinal study Participants: 828 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Higher vitamin D intake is associated with decreased risk of dementia in a multiethnic cohort. 4 key findings →
Design: longitudinal study Participants: 329 Evidence: moderate
Full summary, score breakdown and related studies → Original source
This review of reviews provides a comprehensive and systematic overview of epidemiological evidence from previously conducted research to assess the associations of physical activity with physical and mental health outcomes in older adults. 1 key finding →
Design: meta-analysis Evidence: high
Full summary, score breakdown and related studies → Original source
In patients aged 65 years and older undergoing hip fracture surgery, regional anesthesia without sedation did not significantly reduce the incidence of postoperative delirium compared with general anesthesia. 3 key findings →
Design: open-label trial Participants: 476 Evidence: high
Full summary, score breakdown and related studies → Original source
The use of benzodiazepines or opioids in the ICU is associated with longer duration of a first episode of delirium. 5 key findings →
Design: cohort study Participants: 304 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Potentially modifiable factors consistently associated with increased likelihood of weight loss, low BMI, or poor nutrition included depression, impaired function, and poor oral intake. 5 key findings →
Participants: 100 Evidence: low
Full summary, score breakdown and related studies → Original source
Preoperative determination of dementia status is important for risk stratification for incident delirium after acute hip fracture repair surgery because types and magnitude of predisposing risk factors for postoperative delirium substantially differ based on preoperative dementia status. 3 key findings →
Design: cohort study Participants: 284 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Zolpidem use was a strong, independent, and potentially modifiable risk factor for inpatient falls. 5 key findings →
Design: cohort study Participants: 4,962 Evidence: moderate
Full summary, score breakdown and related studies → Original source
OH and RBD yielded individual and combined negative effects on disability in α-synucleinopathies, reflecting a 'malignant' phenotype of PD with early cognitive impairment and postural instability. 3 key findings →
Design: meta-analysis Evidence: high
Full summary, score breakdown and related studies → Original source
Persons dying with advanced dementia admitted to nursing homes have different characteristics compared to those admitted to home care services. 3 key findings →
Design: cohort study Participants: 2,730 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Community-based palliative care of people who die with or of dementia is relatively infrequent but associated with significant reductions in hospital emergency department use in the last year of life. 3 key findings →
Design: cohort study Participants: 5,261 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Pre-existing dementia is not independently associated with mortality, disability, or institutionalization after ischemic stroke. 1 key finding →
Design: cohort study Participants: 877 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Enrollees in a comprehensive dementia care comanagement program had high engagement in advance care planning, high rates of hospice use, and low acute care utilization near the end of life. 1 key finding →
Design: retrospective cohort Participants: 321 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Even though the provision of PC was empirically recognised as a care step in the management of dementia, there are barriers that hinder access of patients with dementia to appropriate facilities. 2 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
The majority of residents were stable in their care dependency status over two subsequent 6-month periods. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
This study has shown the MNA to be a more appropriate nutrition assessment tool for older patients when compared to the SGA. 3 key findings →
Participants: 43 Evidence: low
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 28,180 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 28,180 records, built mostly from automated pulls of Europe PMC (61.7% of the library) and OpenAlex (18.1%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →