27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
Our findings suggest differences in local cortical organization by neighborhood disadvantage, which also mediated the relationship between ADI and cognitive performance, providing a possible network‐based mechanism, explaining risk for cognitive decline and dementia associated with disadvantaged neighborhoods. 3 key findings →
Participants: 526 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The study sample was NHATS respondents who needed assistance with activities of daily living (ADL) or instrumental activities of daily living (IADL), and who did not live with a spouse (N = 512). 3 key findings →
Participants: 512 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Neighborhood disadvantage in later life is associated with poorer cognition and increased vulnerability to dementia. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Type 2 diabetes (T2DM) significantly increases the risk of dementia due to overlapping metabolic, molecular, and genetic factors. 1 key finding →
Evidence: low
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The aging population is increasingly affected by both diabetes mellitus and hearing loss, two conditions that often coexist and can significantly impact quality of life. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The findings indicate that the burden of dementia is rising in East and Southeast Asia, with women showing a higher burden across all indicators. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
We investigated the effect of using smartphone-based calendars (Google and Outlook Calendar) on prospective memory in Alzheimer's disease (AD). we recruited two groups of participants with mild AD. 1 key finding →
Evidence: low
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It has been reported that taurine intake in the past may have a positive effect on present cognitive function in the elderly. 4 key findings →
Design: cross-sectional Participants: 481 Evidence: low
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In the continuously aging society, private sectors are expected to play a role in older adult care. 2 key findings →
Evidence: low
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An Interprofessional Virtual Healthcare Neighborhood (VHN) was designed to deliver information, peer support, and professional guidance to caregivers of individuals with dementia. 2 key findings →
Participants: 28 Evidence: low
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This study investigated the current status and distribution of Alzheimer's disease (AD) among Mongolian and Han individuals who were at least 55 years old and living in rural areas of Inner Mongolia. 2 key findings →
Participants: 9,266 Evidence: low
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Accessibility to food stores offering nutritious and affordable options is critical to ensure urban residents lead healthy lives. 2 key findings →
Evidence: low
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Artificial food colors (AFCs) in foods and beverages may be harmful to children. 1 key finding →
Evidence: low
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We found the common trends of increasing spatial patterning of housing prices and all-cause mortality. 5 key findings →
Evidence: low
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The organization and possible functions of basal forebrain and pontine cholinergic systems are reviewed. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
The cytokine interleukin 1 (IL-1) has diverse actions in the brain. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The suprachiasmatic nucleus, considered to be the endogenous circadian clock in the mammalian brain, shows morphological changes with aging, which become even more pronounced in Alzheimer's disease (AD). 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Sleep-wake rhythm disturbances in patients with Alzheimer's disease (AD) make a strong demand on caregivers and are among the most important reasons for institutionalization. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Three closely related forms of glycogen synthase kinase 3 (GSK-3alpha, GSK-3beta and GSK-3beta2) have a major role in Wnt and Hedgehog signaling pathways and regulate the cell-division cycle, stem-cell renewal and differentiation, apoptosis, circadian rhythm, transcription and insulin action. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Sirtuins are nicotinamide adenine dinucleotide (NAD+)-dependent deacylases that have traditionally been linked with calorie restriction and aging in mammals. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Acetylcholine is widely distributed in the nervous system and has been implicated to play a critical role in cerebral cortical development, cortical activity, controlling cerebral blood flow and sleep-wake cycle as well as in modulating cognitive performances and learning and memory processes. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Sleep has important homeostatic functions, and sleep deprivation is a stressor that has consequences for the brain, as well as many body systems. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Increased levels of circulating AVP are also associated with the risk for suicide. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Adenosine is a ubiquitous homeostatic substance released from most cells, including neurones and glia. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Nicotine maintains tobacco addiction and has therapeutic utility to aid smoking cessation and possibly to treat other medical diseases. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →