27,780 Alzheimer's and dementia studies in plain English, each scored out of 100.
There was no significant reduction in hospital transfers per 1000 person-days alive in the intervention vs control groups (rate [SE], 3.7 [0.2]; 95% CI, 3.4-4.0 vs 3.9 [0.3]; 95% CI, 3.6-4.1; rate difference [SE], -0.2 [0.3]; 95% CI, -0.5 to 0.2). 3 key findings →
Participants: 4,171 Evidence: high
Full summary, score breakdown and related studies → Original source
We present a range of trigger tools spanning different hospital settings and patient populations. 1 key finding →
Design: systematic review Participants: 17,000 Evidence: high
Full summary, score breakdown and related studies → Original source
Concerning deceased residents, we collected 551 of 610 questionnaires from staff at baseline and 984 of 1178 postintervention in 37 intervention and 36 control homes. 2 key findings →
Evidence: high
Full summary, score breakdown and related studies → Original source
Studies implementing research methods (30 studies) demonstrated the role of family members as both proxy decision-makers and supporting decision-making for the person with impaired capacity. 2 key findings →
Design: systematic review Participants: 19 Evidence: high
Full summary, score breakdown and related studies → Original source
Knowledge of CPR, MV, TF, and self-efficacy to make EOL treatment decisions increased significantly more in the ACT-Plan group at weeks 4 and 20. 2 key findings →
Design: randomized controlled trial Participants: 173 Evidence: high
Full summary, score breakdown and related studies → Original source
These findings highlight the potential benefits of palliative care in some non-cancer illnesses. 5 key findings →
Design: cohort study Participants: 6,936 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Decision-making interventions typically consist of multiple components which aim to establish preferences for future health care. 1 key finding →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
Future studies are needed to evaluate the benefits and harms of using antibiotics for patients during EOL care in diverse patient populations. 3 key findings →
Design: meta-analysis Evidence: high
Full summary, score breakdown and related studies → Original source
Four key themes were identified in this review: goals of care and end-of-life conversations, symptom management, emergency room visits, and prescribing behavior. 5 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
ACP is complex, and trial characteristics were heterogeneous. 2 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
Real-world deprescribing patterns of antihypertensives among NH residents with HTN and LLE/AD appear to reflect variation in recommendations for HTN treatment intensity and individualization of patient care in a population with potential overtreatment. 5 key findings →
Design: cohort study Participants: 10,574 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Most veterans with LLE/AD taking statins for secondary prevention do not discontinue statins following CLC admission. 2 key findings →
Design: cohort study Participants: 13,110 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Older adults at the end of life receive a high number of hours of help at the end of life, many from more than one caregiver, which may shape hospice access. 3 key findings →
Design: cohort study Participants: 1,868 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Importance and objective Conducting advance care planning (ACP) conversations with people with dementia and their relatives contributes to providing care according to their preferences. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
After backward stepwise selection in year 0, the following factors were associated with increased risk of death by more than 10%: being hospitalized; having congestive heart failure, chronic obstructive pulmonary disease, or dementia; having moderate to high pain; having worse well-being; having functional status in the transitional or end-of-life phase; having any problems with appetite; receiving end-of-life home care; and living in a nursing home. 2 key findings →
Participants: 494 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Advance care planning is acceptable for people with dementia and their carers and is associated with improved outcomes. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Recording of a palliative care approach for non-cancer conditions has increased since the introduction of the UK End-of-Life Care Strategy, but remains inadequate. 2 key findings →
Design: cross-sectional Participants: 5,426 Evidence: low
Full summary, score breakdown and related studies → Original source
For evaluating factors associated with POLST-discordant care, the outcome was ICU admission contrary to POLST order for medical interventions during the last hospitalization of life. 5 key findings →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source
Mortality of the residents living in NHs with COVID-19 was almost 45%. 5 key findings →
Participants: 430 Evidence: low
Full summary, score breakdown and related studies → Original source
The findings of this study suggest that concurrent with new initiatives aimed at reducing hospitalizations, hospital transfers declined between 2011 and 2017 among nursing home residents with advanced illnesses without increased mortality rates. 2 key findings →
Design: cross-sectional Evidence: moderate
Full summary, score breakdown and related studies → Original source
Comprehensive nurse practitioner dementia care co-management reduced ED visits, shortened hospital length of stay, increased hospice use, and delayed admission to long-term care. 3 key findings →
Participants: 856 Evidence: low
Full summary, score breakdown and related studies → Original source
The ZBI-7 is a valid instrument for measuring caregiver burden in PC. 2 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
At ward level, professionals and residents rated the average achieved level of shared decision-making 71.53/100 (σ = 16.09) and 81.11/100 (σ = 19.18) respectively. 2 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
Among 927 hospitalized patients with dementia, 17% received IPCC (N = 157). 5 key findings →
Participants: 157 Evidence: low
Full summary, score breakdown and related studies → Original source
Persons with dementia are at high risk for loss of decision-making ability due to increased cognitive decline as the disease progresses. 1 key finding →
Participants: 40 Evidence: low
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,780 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,780 records, built mostly from automated pulls of Europe PMC (61.1% of the library) and OpenAlex (18.3%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →