27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
Family members of persons with advanced dementia may be asked to make complex treatment decisions without having adequate knowledge regarding the risks and benefits. 1 key finding →
Design: randomized controlled trial Evidence: high
Full summary, score breakdown and related studies → Original source
Individuals with AD comprise a substantial number of older adult deaths in the United States, a number expected to rise considerably in coming decades. 1 key finding →
Design: longitudinal study Participants: 10,802 Evidence: moderate
Full summary, score breakdown and related studies → Original source
The majority of residents were stable in their care dependency status over two subsequent 6-month periods. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Successful strategies from other disciplines could be considered by palliative care researchers. 1 key finding →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
Significant comorbidities were discovered at autopsy in individuals with dementia. 2 key findings →
Design: cohort study Participants: 86 Evidence: moderate
Full summary, score breakdown and related studies → Original source
The cohort experienced 496 suspected infections; 72.4% were treated with antimicrobials, most commonly quinolones (39.8%) and third- or fourth-generation cephalosporins (20.6%). 3 key findings →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source
The results highlight the need to integrate palliative care with optimal disease management in primary practice and to initiate advance care planning early in the chronic disease trajectory to enable all patients to live as well as possible with progressive illness and die with dignity and comfort. 2 key findings →
Design: cross-sectional Participants: 1,491 Evidence: low
Full summary, score breakdown and related studies → Original source
Direct measurement of prevalence of palliative care needs on a population basis is feasible. 1 key finding →
Design: cross-sectional Participants: 785 Evidence: low
Full summary, score breakdown and related studies → Original source
Most NH residents who use statins at the time of progression to advanced dementia continue use in follow-up. 5 key findings →
Participants: 1,699 Evidence: moderate
Full summary, score breakdown and related studies → Original source
The purpose of this retrospective, cross-sectional study was to determine the prevalence of advance care planning (ACP) among older people presenting to an Emergency Department (ED) from the community or a residential aged care facility. 3 key findings →
Design: cross-sectional Participants: 40 Evidence: low
Full summary, score breakdown and related studies → Original source
Of 5406 nursing home residents with advanced dementia, 2911 (53.9%) received at least 1 medication with questionable benefit (range, 44.7% in the Mid-Atlantic census region to 65.0% in the West South Central census region). 3 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
We identified 101 deaths of residents with dementia in 69 nursing homes (58% response rate). 2 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
The results of our study contribute to a better understanding of the factors hindering GPs in initiating ACP. 2 key findings →
Participants: 36 Evidence: low
Full summary, score breakdown and related studies → Original source
Residents and relatives experience ethical challenges in Norwegian nursing homes, mostly connected to "everyday ethical issues." 5 key findings →
Participants: 25 Evidence: low
Full summary, score breakdown and related studies → Original source
A large proportion of patients with ECI decline ACP discussions and the reasons are influenced by personal values, coping behaviours and sociocultural norms. 3 key findings →
Participants: 93 Evidence: low
Full summary, score breakdown and related studies → Original source
The percentage of psychological distress was similar between caregivers of cancer patients (77.6%) and caregivers of dementia patients (72.4%). 3 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
Preexisting physician attitudes, knowledge, and beliefs prevent emergency physicians from addressing PC needs for AD patients. 1 key finding →
Participants: 548 Evidence: low
Full summary, score breakdown and related studies → Original source
The current practice of palliative care in Belgium is far from the presently considered ideal palliative care approaches. 1 key finding →
Participants: 20 Evidence: low
Full summary, score breakdown and related studies → Original source
The decision-support intervention piloted in this study was feasible and relevant for surrogate decision-makers of persons with advanced dementia in NHs, and it improved quality of communication between SDM and NH providers. 1 key finding →
Evidence: high
Full summary, score breakdown and related studies → Original source
We systematically reviewed randomized clinical trials of problem-solving therapy (PST) in older adults. 5 key findings →
Evidence: high
Full summary, score breakdown and related studies → Original source
Chronic heart failure (CHF) is the leading cause of hospitalization for those over the age of 65 and represents a significant clinical and economic burden. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Place of death of older people who died from a dementia-related disease differs substantially between countries, which might point to organizational differences in end-of-life care provision. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
It is difficult to define what constitutes high-quality end-of-life care for people with dementia from the perspective of family carers. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Future palliative care policy decisions in Ireland must consider the rapidly aging Irish population with the accompanying increase in deaths from cancer, dementia, and neurodegenerative disease and associated palliative care need. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
The ongoing change in long-term care from institutional care to housing services causes major challenges to the continuity of end-of-life care. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →