27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
The identification of mutations in the Tau gene in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) has made it possible to express human tau protein with pathogenic mutations in transgenic animals. 5 key findings →
Evidence: low
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Limited literacy is independently associated with a nearly 2-fold increase in mortality in the elderly. 5 key findings →
Evidence: low
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Cross-sectional study, Health, Aging and Body Composition data (1999/2000). 2 key findings →
Design: cross-sectional Evidence: low
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By contrast, participants in the highest handgrip strength quartile maintained a higher level of cognitive function. 2 key findings →
Design: prospective cohort Evidence: moderate
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The finding of similar prevalence estimates for depression in men and women was not consistent with prior research that has shown a female predominance. 3 key findings →
Participants: 851 Evidence: low
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The finding of higher mortality and worse mobility for nonwhite patients with hip fractures highlights the need for more research on race/ethnicity disparities in hip fracture care. 3 key findings →
Participants: 2,692 Evidence: moderate
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Prevalence of dementia subtypes in China is comparable with that in Western countries. 1 key finding →
Design: cross-sectional Participants: 99 Evidence: low
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We studied 40,492 hypertensive patients taking at least one antihypertensive drug class. 1 key finding →
Participants: 40,492 Evidence: low
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Our objective was to determine whether the consumption of green tea, coffee, or black tea influences the incidence of dementia and mild cognitive impairment (MCI) in older people. 3 key findings →
Participants: 723 Evidence: low
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BPSD are universally present, bear correlates with dementia type and severity, and cause significant caregiver distress. 2 key findings →
Design: cross-sectional Participants: 107 Evidence: low
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Black race was associated with greater dementia risk even after adjustment for education and other potential confounders. 4 key findings →
Design: longitudinal study Evidence: moderate
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A location dynamics model and ADRD-focused future directions are offered for guiding rural practitioners, researchers, and policymakers in mitigating rural disparities. 1 key finding →
Evidence: low
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The Alzheimer's Association hosted the second Latinos & Alzheimer's Symposium in May 2021. 2 key findings →
Evidence: low
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Future studies need to examine underlying processes and develop interventions to reduce disparities while also being more broadly inclusive of diverse populations. 1 key finding →
Evidence: low
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Eleven studies met the inclusion criteria. 5 key findings →
Design: systematic review Evidence: high
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Directives to forgo hospitalization for U.S. NH residents with advanced dementia are uncommon and are associated with the organizational features of the facilities caring for them and the intensity of end-of-life care practiced in the region, as well as individual resident characteristics. 5 key findings →
Design: cross-sectional Participants: 91,521 Evidence: low
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Care for U.S. nursing home residents with LRI and dementia is more aggressive than care for Dutch residents, particularly in residents with severe dementia. 3 key findings →
Design: cohort study Participants: 36 Evidence: moderate
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Compared with white patients, black patients were less likely to have heart failure with preserved systolic function. 3 key findings →
Participants: 11,994 Evidence: low
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Future studies should emphasize collection of relevant psychosocial factors in addition to the development of intentional diversity and inclusion efforts to improve the racial/ethnic and socioeconomic representativeness of AD studies. 1 key finding →
Participants: 131 Evidence: low
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A cross-sectional study of geriatric patients was performed to provide a comprehensive description of the prevalence and clinical characteristics of chronic itch affecting Hispanic geriatric subjects in Mexico. 1 key finding →
Design: cross-sectional Participants: 302 Evidence: low
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The prevalence of dementia in this rural Tanzanian population is similar to that reported in high-income countries. 3 key findings →
Design: cross-sectional Participants: 1,198 Evidence: low
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As ADRD deaths at home increase, the need for caregiver support and home-based palliative care may become more critical. 5 key findings →
Design: cross-sectional Evidence: low
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Limited studies focusing on the intersectional determinants of preferences of ethnic minority groups or post-migrants with dementia were found. 5 key findings →
Design: systematic review Evidence: high
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The cultural tailoring of interventions is promising to address disparities in dementia care and interventions in underserved communities. 4 key findings →
Design: randomized controlled trial Evidence: high
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A total of 400 103 AF and dementia-related deaths were recorded between 2000 and 2020. 5 key findings →
Participants: 400 Evidence: low
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Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →