This chapter reviews the neurological phenotype of Down syndrome (DS) in early development, childhood, and aging. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
This chapter reviews the neurological phenotype of Down syndrome (DS) in early development, childhood, and aging. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Thirty-one patients with Wilson's disease were evaluated with detailed neurologic and medical examinations. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The focus of this review is on the close relationship between gait and cognition in ageing and associated dementias. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
This paper examines key challenges and strategies for including older people with dementia in an ethnographic study of quality of life in institutional care settings. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
A group of 18 long‐stay patients with a diagnosis of schizophrenia were compared with a group of 10 age‐matched subjects who had been institutionalized by reason of physical disease, on performance on tests of intellectual function; and with a group of agematched healthy subjects, both on tests of intellectual function, and radiographically, using the technique of computerized axial tomography (EMI scan) of the brain. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
✓ Thirty-eight cases of colloid cyst of the third ventricle are reviewed. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
This study investigated three aspects of processing materials with emotional content in patients with idiopathic Parkinson's disease (PD): the ability to produce affective prosody, to discriminate affectively loaded speech, and to detect the surprise element in humorous sketches. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
Alzheimer's disease (AD) is the most common cause of dementia in the elderly population. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
Huntington's disease (HD) is a devastating neuropsychiatric disorder for which therapeutic interventions have been rather fruitless to date, except in a slight symptomatic relief. 3 key findings →
Design: open-label trial Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
This study adds further arguments for a cognitive impairment in MND/ALS. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
The Alzheimer's disease (AD) is recognized as one of the most common neurodegenerative causes of dementia worldwide, having been characterized by progressive cognitive decline for the most part. 2 key findings →
Participants: 461 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Three blood gene expression datasets of high dimensionality and low sample size (HDLSS) have been utilized in this study, with one dataset exhibiting significant class imbalance. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Peripheral auditory status was statistically similar between subject groups. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
Dementia, a complex and debilitating spectrum of neurodegenerative diseases, presents a profound challenge in the quest for effective treatments. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Digital health innovations hold diagnostic and therapeutic promise but may be subject to biases for underrepresented groups. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The early diagnosis of dementia, a progressive condition impairing memory, cognition, and functional ability in older adults, is essential for timely intervention and improved patient outcomes. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Alzheimer’s disease (AD) stands as a prevalent form of dementia, primarily impacting the elderly, and presently lacking any known cure. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
It was found that the top cited 100 articles came from 51 journals and 31 countries. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Butyrylcholinesterase inhibition offers one of the formulated solutions to tackle the aggravating symptoms of dementia that downgrades to cholinergic neuronal loss in Alzheimer’s disease. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
Research on AI's role in diagnosing neurological disorders is becoming widely recognized for its growing importance. 2 key findings →
Participants: 276 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The authors summarize developments in the concept of working memory as a multicomponent system, beginning by contrasting this approach with alternative uses of the term working memory. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Recently developed robotics technologies are used not only in factories, but also in our daily living environment. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Spontaneous, conversational speech in probable dementia of Alzheimer type (DAT) participants and healthy older controls was analysed using eight linguistic measures. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Parkinson disease is a progressive neurologic disorder afflicting approximately 1 percent of Americans older than 60 years. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →