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Home › Research › Topics › positron

positron

319 studies tagged positron, dated 1995-07-01 to 2026-11-01. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Large-scale head-to-head comparison of on- and off-target profiles of [18F]Tauvid and [18F]MK6240 tau-PET in aging and Alzheimer’s disease 2026-11-01
  2. Detection of tau spatial extent using MK6240 and flortaucipir PET 2026-10-28
  3. Soluble amyloid composition links proximal APP processing, fibrillar burden and the p-tau181 response 2026-10-22

Studies

319 studies carry this tag.

Date range

1995 to 2026

Top journals

  • Alzheimer's & dementia : the journal of the Alzheimer's Association 37
  • Alzheimer's research & therapy 21
  • Brain : a journal of neurology 18
  • Alzheimer's & dementia (Amsterdam, Netherlands) 17
  • Journal of Alzheimer's disease : JAD 15

105 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. [(18)F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2013-02-12 Brain scans and imaging

    [(18)F]T807 demonstrates high affinity and selectivity to PHF-tau as well as favorable in vivo properties, making this a promising candidate as an imaging agent for AD.

  2. Subjective cognitive complaints and amyloid burden in cognitively normal older individuals

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuropsychologia 2012-08-23 Brain scans and imaging

    Accumulating evidence suggests that subjective cognitive complaints (SCC) may indicate subtle cognitive decline characteristic of individuals with preclinical Alzheimer's disease (AD).

  3. Amyloid imaging in Alzheimer's disease: comparison of florbetapir and Pittsburgh compound-B positron emission tomography

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of neurology, neurosurgery, and psychiatry 2012-07-11 Brain scans and imaging

    Both ligands displayed highly significant group discrimination and correlation of regional uptake.

  4. Subjective cognition and amyloid deposition imaging: a Pittsburgh Compound B positron emission tomography study in normal elderly individuals

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Archives of neurology 2012-02-01 Brain scans and imaging

    A decrease of self-confidence about memory abilities in cognitively normal elderly subjects may be related to the neuropathological hallmark of AD measured with PiB-positron emission tomography.

  5. Using PET with 18F-AV-45 (florbetapir) to quantify brain amyloid load in a clinical environment

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. European Journal of Nuclear Medicine and Molecular Imaging 2012-01-17 Brain scans and imaging

    The mean values of SUVr were higher in AD patients (median 1.20, Q1-Q3 1.16-1.30) than in HC subjects (median 1.05, Q1-Q3 1.04-1.08; p = 0.0001) in the overall cortex and all cortical regions (precuneus, anterior and posterior cingulate, and frontal median, temporal, parietal and occipital cortex).

  6. Amyloid vs FDG-PET in the differential diagnosis of AD and FTLD

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Neurology 2011-11-30 Brain scans and imaging

    PiB and FDG showed similar accuracy in discriminating AD and FTLD.

  7. Clinical amyloid imaging in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. The Lancet. Neurology 2011-07-01 Treatments

    The hypothesis that amyloid deposition is the leading cause of Alzheimer's disease (AD) is supported by findings in transgenic animal models and forms the basis of clinical trials of anti-amyloid agents.

  8. PET imaging of brain amyloid in dementia: a review

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. International journal of geriatric psychiatry 2010-12-28 Treatments

    PIB-PET imaging is a sensitive and specific marker for underlying Aβ amyloid deposition and represents an important investigative tool for examining the relationship between amyloid burden, clinical symptoms and structural and functional changes in dementia.

  9. Increased metabolic vulnerability in early-onset Alzheimer's disease is not related to amyloid burden

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Brain : a journal of neurology 2010-01-15 Brain scans and imaging

    Patients with early age-of-onset Alzheimer's disease show more rapid progression, more generalized cognitive deficits and greater cortical atrophy and hypometabolism compared to late-onset patients at a similar disease stage.

  10. Phase 1 study of the Pittsburgh compound B derivative 18F-flutemetamol in healthy volunteers and patients with probable Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009-07-17 Brain scans and imaging

    (18)F-flutemetamol uptake can be readily quantified.

  11. Amyloid imaging in mild cognitive impairment subtypes

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Annals of neurology 2009-05-01 Brain scans and imaging

    Using cutoffs established from a control cohort, we found that 14 (54%) patients had increased levels of PiB retention and were considered "amyloid-positive."

  12. Preclinical evidence of Alzheimer changes: convergent cerebrospinal fluid biomarker and fluorodeoxyglucose positron emission tomography findings

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. Archives of neurology 2009-05 Tau biomarkers

    Voxel-based analyses demonstrated significant negative correlations between CSF tau and ptau(181) levels and CMRglu in the posterior cingulate, precuneus, and parahippocampal regions.

  13. Abeta amyloid and glucose metabolism in three variants of primary progressive aphasia

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Annals of neurology 2008-10-01 Brain scans and imaging

    LPA is associated with Abeta amyloidosis, suggesting that subclassification of PPA based on language features can help predict the likelihood of AD pathology.

  14. Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C]PIB positron emission tomography

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Journal of neurology, neurosurgery, and psychiatry 2008-07-24 Treatments

    This study suggests that amyloid load is significantly raised in over 80% of subjects with DLB, while amyloid pathology is infrequent in PDD.

  15. Longitudinal, quantitative assessment of amyloid, neuroinflammation, and anti-amyloid treatment in a living mouse model of Alzheimer's disease enabled by positron emission tomography

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2007-10-01 Brain scans and imaging

    We provide the first evidence for the capability of a high-resolution positron emission tomographic (PET) imaging system in quantitatively mapping amyloid accumulation in living amyloid precursor protein transgenic (Tg) mice.

  16. Amyloid deposition begins in the striatum of presenilin-1 mutation carriers from two unrelated pedigrees

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2007-06-01 Brain scans and imaging

    The amyloid cascade hypothesis suggests that the aggregation and deposition of amyloid-beta protein is an initiating event in Alzheimer's disease (AD).

  17. 11C-PIB PET imaging in Alzheimer disease and frontotemporal lobar degeneration

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Neurology 2007-04-01 Brain scans and imaging

    PET imaging with (11)C-labeled Pittsburgh Compound-B ((11)C-PIB) helps discriminate Alzheimer disease (AD) from frontotemporal lobar degeneration (FTLD).

  18. Declining brain activity in cognitively normal apolipoprotein E ɛ4 heterozygotes: A foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Proceedings of the National Academy of Sciences 2001-03-13 Genetics

    Cross-sectional positron emission tomography (PET) studies find that cognitively normal carriers of the apolipoprotein E (APOE) epsilon4 allele, a common Alzheimer's susceptibility gene, have abnormally low measurements of the cerebral metabolic rate for glucose (CMRgl) in the same regions as patients with Alzheimer's dementia.

  19. A diagnostic approach in Alzheimer's disease using three-dimensional stereotactic surface projections of fluorine-18-FDG PET

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1995-07-01 Vascular contributions

    3D-SSP enables quantitative data extraction and reliable localization of metabolic abnormalities by means of stereotactic coordinates.

From across this tag

9 of the 319 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 9. The same 9 appear here every time.

All topic tags with their study counts