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Newest in this topic

  1. The modulatory effects of Hericium erinaceus and donepezil on amyloid accumulation and autophagy-associated clearance in Aβ 1-42 -induced N2a cells 2026-10-14
  2. Neuroprotective Effects and Mechanisms of Cannabinoids in In Vitro Cell Models of Neurodegenerative Diseases: A Scoping Review 2026-10-13
  3. Cannabidiol for chronic neuroinflammation: clinical pharmacology and what an interpretable trial will require 2026-10-05

Studies

117 studies carry this tag.

Date range

1995 to 2026

Top journals

  • Molecules (Basel, Switzerland) 5
  • Phytotherapy research : PTR 4
  • Frontiers in aging neuroscience 3
  • International journal of molecular sciences 3
  • Research Square 3

97 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Medical Use of Cannabinoids

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Drugs 2018-11-01 Brain scans and imaging

    As a result, it has been reported that changes in endocannabinoid levels may be related to neurological diseases such as Parkinson's disease, Huntington's disease, Alzheimer's disease and multiple sclerosis, as well as anorexia and irritable bowel syndrome.

  2. Use of Curcumin, a Natural Polyphenol for Targeting Molecular Pathways in Treating Age-Related Neurodegenerative Diseases

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. International journal of molecular sciences 2018-05-31 Treatments

    Progressive accumulation of misfolded amyloid proteins in intracellular and extracellular spaces is one of the principal reasons for synaptic damage and impairment of neuronal communication in several neurodegenerative diseases.

  3. Use of curcumin in diagnosis, prevention, and treatment of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Neural regeneration research 2018-04-01 Treatments

    This review summarizes and describes the use of curcumin in diagnosis, prevention, and treatment of Alzheimer's disease.

  4. Role of Plant Derived Alkaloids and Their Mechanism in Neurodegenerative Disorders

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. International journal of biological sciences 2018-03-09 Treatments

    Neurodegenerative diseases are conventionally demarcated as disorders with selective loss of neurons.

  5. Neuroprotective and Anti-Aging Potentials of Essential Oils from Aromatic and Medicinal Plants

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Frontiers in aging neuroscience 2017-05-30 Costs and economics

    The use of essential oils (EOs) and their components is known since long in traditional medicine and aromatherapy for the management of various diseases, and is further increased in the recent times.

  6. Docosahexaenoic acid (DHA): An essential nutrient and a nutraceutical for brain health and diseases

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Prostaglandins, leukotrienes, and essential fatty acids 2017-03-10 Brain scans and imaging

    Docosahexaenoic acid (DHA), a polyunsaturated fatty acid (PUFA) enriched in phospholipids in the brain and retina, is known to play multi-functional roles in brain health and diseases.

  7. Resveratrol and Grape Extract-loaded Solid Lipid Nanoparticles for the Treatment of Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Molecules (Basel, Switzerland) 2017-02-13 Disease mechanisms

    The aggregation of amyloid-β peptide (Aβ) has been linked to the formation of neuritic plaques, which are pathological hallmarks of Alzheimer's disease (AD).

  8. Natural products against Alzheimer's disease: Pharmaco-therapeutics and biotechnological interventions

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Biotechnology advances 2016-12-30 Drug development

    Alzheimer's disease (AD) is a severe, chronic and progressive neurodegenerative disease associated with memory and cognition impairment ultimately leading to death.

  9. Overviews of Biological Importance of Quercetin: A Bioactive Flavonoid

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Pharmacognosy reviews 2016-07-01 Disease mechanisms

    Antioxidants are substances that may protect cells from the damage caused by unstable molecules such as free radicals.

  10. Potential neuroprotective properties of epigallocatechin-3-gallate (EGCG)

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Nutrition journal 2016-06-07 Costs and economics

    Neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD) enforce an overwhelming social and economic burden on society.

  11. Pomegranate's Neuroprotective Effects against Alzheimer's Disease Are Mediated by Urolithins, Its Ellagitannin-Gut Microbial Derived Metabolites

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. ACS chemical neuroscience 2015-11-17 Disease mechanisms

    Pomegranate shows neuroprotective effects against Alzheimer's disease (AD) in several reported animal studies.

  12. Neurodegenerative diseases: From available treatments to prospective herbal therapy

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurochemistry international 2015-11-10 End-of-life care

    Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and many others represent a relevant health problem with age worldwide.

  13. Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Frontiers in aging neuroscience 2015-04-21 Prevention and risk

    Omega-3 polyunsaturated fatty acids (PUFAs) exhibit neuroprotective properties and represent a potential treatment for a variety of neurodegenerative and neurological disorders.

  14. Regulatory Effects of Caffeic Acid Phenethyl Ester on Neuroinflammation in Microglial Cells

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. International Journal of Molecular Sciences 2015-03-11 Inflammation and the immune system

    Microglial activation has been widely demonstrated to mediate inflammatory processes that are crucial in several neurodegenerative disorders.

  15. Inhibition of Neuroinflammation by Synthetic Androstene Derivatives Incorporating Amino Acid Methyl Esters on Activated BV‐2 Microglia

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. ChemMedChem 2015-03-04 Inflammation and the immune system

    Androstene derivatives incorporating amino acid methyl esters were prepared, and their anti‐inflammatory effects were evaluated in lipopolysaccharide (LPS)‐activated BV‐2 microglial cells.

  16. Edible mushrooms: improving human health and promoting quality life

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. International journal of microbiology 2015-01-20 Prevention and risk

    Mushrooms have been consumed since earliest history; ancient Greeks believed that mushrooms provided strength for warriors in battle, and the Romans perceived them as the "Food of the Gods."

  17. New concepts in nutraceuticals as alternative for pharmaceuticals

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. International journal of preventive medicine 2014-12-01 Brain scans and imaging

    Nutraceuticals are products, which other than nutrition are also used as medicine.

  18. Polyunsaturated fatty acids and their metabolites in brain function and disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Nature reviews. Neuroscience 2014-11-12 Risk factors

    The brain is highly enriched with fatty acids.

  19. Investigation of the effects of solid lipid curcumin on cognition and mood in a healthy older population

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Journal of Psychopharmacology 2014-10-02 Clinical trials

    Curcumin possesses many properties which may prevent or ameliorate pathological processes underlying age-related cognitive decline, dementia or mood disorders.

  20. Effects of several quinones on insulin aggregation

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Scientific reports 2014-07-10 Treatments

    Protein misfolding and aggregation are associated with more than twenty diseases, such as neurodegenerative diseases and metabolic diseases.

  21. Cerium oxide nanoparticle: a remarkably versatile rare earth nanomaterial for biological applications

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. NPG Asia Materials 2014-03-01 Risk factors

    Cerium oxide nanoparticles (CeONPs) have attracted much attention because they possess multi-enzyme mimetic properties and have been used in bioanalysis, biomedicine, drug delivery, bioscaffold and so on.

  22. Curcumin and Curcumin-like Molecules: From Spice to Drugs

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Current Medicinal Chemistry 2013-12-21 Disease mechanisms

    Curcumin is the major yellow pigment extracted from turmeric, a commonly used spice in Asian cuisine and extensively employed in ayurvedic herbal remedies.

  23. Puerarin: a review of pharmacological effects

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Phytotherapy research : PTR 2013-12-13 Prevention and risk

    Puerarin is the major bioactive ingredient isolated from the root of the Pueraria lobata (Willd.)

  24. Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Alzheimer's research & therapy 2012-10-29 Biomarkers

    Mean age of completers (n = 30) was 73.5 years and mean Mini-Mental Status Examination (MMSE) score was 22.5.

  25. Anthocyanin-enriched bilberry and blackcurrant extracts modulate amyloid precursor protein processing and alleviate behavioral abnormalities in the APP/PS1 mouse model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of nutritional biochemistry 2012-09-17 Biomarkers

    A growing body of epidemiological evidence suggests that fruit and vegetable juices containing various phenolic compounds can reduce the risk of Alzheimer's disease (AD).

  26. Target-based selection of flavonoids for neurodegenerative disorders

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Trends in pharmacological sciences 2012-09-12 Risk factors

    Habitual consumption of dietary flavonoids known to improve mitochondrial bioenergetics and inhibit various secondary sources of reactive oxygen species (ROS) reduces the risk for neurodegenerative disorders such as Parkinson's disease (PD), stroke, and Alzheimer's disease (AD).

  27. Natural products as a rich source of tau-targeting drugs for Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Future medicinal chemistry 2012-09-01 Drug development

    Alzheimer's disease (AD) is a neurodegenerative disorder and the most common form of dementia, affecting more than 5.4 million people in the USA.

  28. Curcumin loaded-PLGA nanoparticles conjugated with Tet-1 peptide for potential use in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. PloS one 2012-03-05 Treatments

    Alzheimer's disease is a growing concern in the modern world.

  29. Omega-3 fatty acids EPA and DHA: health benefits throughout life

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Advances in nutrition (Bethesda, Md.) 2012-01-05 Brain scans and imaging

    Omega-3 [(n-3)] fatty acids have been linked to healthy aging throughout life.

  30. Neuronal uptake and neuroprotective effect of curcumin-loaded PLGA nanoparticles on the human SK-N-SH cell line

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of Alzheimer's disease : JAD 2012-01-01 Treatments

    Curcumin, a natural polyphenolic pigment present in the spice turmeric (Curcuma longa), is known to possess a pleiotropic activity such as antioxidant, anti-inflammatory, and anti-amyloid-β activities.

  31. Neuroprotective potential of phytochemicals

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Pharmacognosy Reviews/Bioinformatics Trends/Pharmacognosy review 2012-01-01 Risk factors

    Cognitive dysfunction is a major health problem in the 21st century, and many neuropsychiatric disorders and neurodegenerative disorders, such as schizophrenia, depression, Alzheimer's Disease dementia, cerebrovascular impairment, seizure disorders, head injury and Parkinsonism, can be severly functionally debilitating in nature.

  32. Docosahexaenoic acid signalolipidomics in nutrition: significance in aging, neuroinflammation, macular degeneration, Alzheimer's, and other neurodegenerative diseases

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Annual review of nutrition 2011-08-01 Prevention and risk

    Essential polyunsaturated fatty acids (PUFAs) are critical nutritional lipids that must be obtained from the diet to sustain homeostasis.

  33. The targets of curcumin

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Current drug targets 2011-03-01 Treatments

    Curcumin (diferuloylmethane), an orange-yellow component of turmeric or curry powder, is a polyphenol natural product isolated from the rhizome of the plant Curcuma longa.

  34. Oleuropein and derivatives from olives as Tau aggregation inhibitors

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurochemistry international 2011-02-17 Drug development

    Tau isoforms constitute a family of microtubule-associated proteins that are mainly expressed in neurons of the central nervous system.

  35. Clioquinol: review of its mechanisms of action and clinical uses in neurodegenerative disorders

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. CNS neuroscience & therapeutics 2010-12-27 Disease mechanisms

    Clioquinol was produced as a topical antiseptic and marketed as an oral intestinal amebicide in 1934, being used to treat a wide range of intestinal diseases.

  36. Flavonoids and Isoflavonoids: From Plant Biology to Agriculture and Neuroscience

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. PLANT PHYSIOLOGY 2010-10-01 Prevention and risk

    For example, the early advances in floral genetics were primarily the result of the ease of screening for mutations impacting flavonoid-derived flower colors, and the first demonstration of epigenetic gene silencing in plants was likewise associated with flavonoid biosynthesis (Jorgensen, 1995).

  37. (-)-epigallocatechin-3-gallate (EGCG) maintains kappa-casein in its pre-fibrillar state without redirecting its aggregation pathway

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of molecular biology 2009-07-17 Treatments

    The polyphenol (-)-epigallocatechin-3-gallate (EGCG) has recently attracted much research interest in the field of protein-misfolding diseases because of its potent anti-amyloid activity against amyloid-beta, alpha-synuclein and huntingtin, the amyloid-fibril-forming proteins involved in Alzheimer's, Parkinson's and Huntington's diseases, respectively.

  38. Gold nanoparticles in nanomedicine: preparations, imaging, diagnostics, therapies and toxicity

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Chemical Society reviews 2009-04-21 Risk factors

    This critical review provides an overall survey of the basic concepts and up-to-date literature results concerning the very promising use of gold nanoparticles (AuNPs) for medicinal applications.

  39. Nitrones as therapeutics

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Free radical biology & medicine 2008-08-29 Risk factors

    Nitrones have the general chemical formula X-CH=NO-Y. They were first used to trap free radicals in chemical systems and then subsequently in biochemical systems.

  40. Therapeutic applications of pomegranate (Punica granatum L.): a review

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. PubMed 2008-06-01 Risk factors

    The pomegranate, Punica granatum L., is an ancient, mystical, unique fruit borne on a small, long-living tree cultivated throughout the Mediterranean region, as far north as the Himalayas, in Southeast Asia, and in California and Arizona in the United States.

  41. Curcuminoids inhibit multiple human cytochromes P450, UDP-glucuronosyltransferase, and sulfotransferase enzymes, whereas piperine is a relatively selective CYP3A4 inhibitor

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Drug metabolism and disposition: the biological fate of chemicals 2008-05-14 Disease mechanisms

    Curcuminoid extract and piperine are being evaluated for beneficial effects in Alzheimer's disease, among other intractable disorders.

  42. Six-Month Randomized, Placebo-Controlled, Double-Blind, Pilot Clinical Trial of Curcumin in Patients With Alzheimer Disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Journal of Clinical Psychopharmacology 2008-02-01 Clinical trials

    Baum, Larry PhD; Lam, Christopher Wai Kei PhD; Cheung, Stanley Kwok-Kuen MSc; Kwok, Timothy MD; Lui, Victor MRCPsych; Tsoh, Joshua MRCPsych; Lam, Linda MD, MRCPsych; Leung, Vivian FHKCPsy; Hui, Elsie FRCP; Ng, Chelsia HBSc; Woo, Jean MD; Chiu, Helen Fung Kum FRCPsych; Goggins, William B. ScD; Zee, Benny Chung-Ying PhD; Cheng, King Fai MD; Fong, Carmen Yuet Shim RN; Wong, Adrian BSc; Mok, Hazel BSc; Chow, Moses Sing Sum PharmD; Ho, Ping Chuen PhD; Ip, Siu Po PhD; Ho, Chung Shun PhD; Yu, Xiong Wen PhD; Lai, Caroline Yau Lin MMedSc; Chan, Ming-Houng FHKCPhys; Szeto, Samuel FRCP; Chan, Iris Hiu Shuen PhD; Mok, Vincent MD Author Information

  43. Curcumin as "Curecumin": from kitchen to clinic

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Biochemical pharmacology 2007-08-19 Risk factors

    Although turmeric (Curcuma longa; an Indian spice) has been described in Ayurveda, as a treatment for inflammatory diseases and is referred by different names in different cultures, the active principle called curcumin or diferuloylmethane, a yellow pigment present in turmeric (curry powder) has been shown to exhibit numerous activities.

  44. Cannabidiol in vivo blunts beta-amyloid induced neuroinflammation by suppressing IL-1beta and iNOS expression

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. British journal of pharmacology 2007-06-25 Biomarkers

    The results of the present study confirm in vivo anti-inflammatory actions of CBD, emphasizing the importance of this compound as a novel promising pharmacological tool capable of attenuating Abeta evoked neuroinflammatory responses.

  45. Curcumin labels amyloid pathology in vivo , disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Journal of Neurochemistry 2007-03-29 Vascular contributions

    Alzheimer's disease (AD) is characterized by senile plaques and neurodegeneration although the neurotoxic mechanisms have not been completely elucidated.

  46. Omega-3 fatty acids, pro-inflammatory signaling and neuroprotection

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Current opinion in clinical nutrition and metabolic care 2007-03-01 Brain scans and imaging

    Recent findings The docosahexaenoate-derived mediator neuroprotectin D1 is formed in retinal pigment epithelial cells when confronted with oxidative stress, in the brain during experimental stroke, and in the human brain from Alzheimer's disease patients as well as in human brain cells in culture.

  47. Curcumin: the Indian solid gold

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Advances in experimental medicine and biology 2007-01-01 Risk factors

    Turmeric, derived from the plant Curcuma longa, is a gold-colored spice commonly used in the Indian subcontinent, not only for health care but also for the preservation of food and as a yellow dye for textiles.

  48. Randomized controlled trial of standardized Bacopa monniera extract in age-associated memory impairment

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Indian journal of psychiatry 2006-10 Clinical trials

    SBME produced significant improvement on mental control, logical memory and paired associated learning during the 12-week drug therapy.

  49. Inhibition of amyloid fibril formation by polyphenols: structural similarity and aromatic interactions as a common inhibition mechanism

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Chemical biology & drug design 2006-01-01 Risk factors

    The formation of well-ordered fibrillar protein deposits is common to a large group of amyloid-associated disorders.

  50. Curcumin: getting back to the roots

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Annals of the New York Academy of Sciences 2005-11-01 Costs and economics

    The use of turmeric, derived from the root of the plant Curcuma longa, for treatment of different inflammatory diseases has been described in Ayurveda and in traditional Chinese medicine for thousands of years.

From across this tag

3 of the 117 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 3. The same 3 appear here every time.

All topic tags with their study counts