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Newest in this topic

  1. Tau-CTFP: A connectome-informed continuous-time first-passage model for forecasting the onset of regional tau PET abnormality 2026-10-30
  2. A Wasserstein Weisfeiler-Lehman Kernel Framework for Multimodal Brain Connectome Analysis 2026-10-29
  3. Current gaps in downstream applications of fMRI foundation models: lessons learned from BrainLM & BrainHarmonix on Prevent-AD 2026-10-26

Studies

205 studies carry this tag.

Date range

2006 to 2026

Top journals

  • Research Square 22
  • medRxiv 22
  • NeuroImage 14
  • bioRxiv 14
  • Preprints.org 7

87 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. An Integrative Multimodal Model for Early Diagnosis of Dementia and Differential Diagnosis of Alzheimer’s Disease Using Neuroimaging, Polygenic Risk, and Cognitive Assessments

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. medRxiv 2026-08-03 Getting a diagnosis

    Multimodal integration of cognitive, neuroimaging, and polygenic data in the MHS-RWD tool yields strong discrimination for both early diagnosis of dementia and AD differential diagnosis.

  2. Consensus Risk Modeling and Uncertainty Quantification of Alzheimer’s Disease Using 5ADCSI Plasma Biomarkers and Multiple External Machine-Learning Frameworks

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. medRxiv 2026-08-02 Biomarkers

    All three frameworks recognized biologically coherent AD-related signal despite differences in training cohort and assay methodology.

  3. Heterogeneity in Multimodal AI Feature Engineering Utility for Explaining Change in Dementia

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. PsyArXiv 2026-08-01 Cognitive tests and assessment

    The present work builds upon progress in foundation artificial intelligence (AI) models for thepurpose of supporting the Alzheimer’s Disease Neuroimaging Initiative (ADNI).

  4. Artificial Intelligence in Alzheimer’s Disease: Evidence Maturity and Clinical Translation Across the Care Pathway

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. Preprints.org 2026-07-30 Treatments

    Artificial intelligence (AI) is now a credible translational research platform across the Alzheimer’s disease (AD) pathway, but its clinical value is often difficult to judge from performance metrics alone.

  5. Edge-Based ADL Recognition Using Room-Specialized Mixture-of-Experts

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. medRxiv 2026-07-27 Digital health tools

    Activities of daily living (ADLs) provide important indicators of functional decline in people living with dementia, motivating the need for continuous in-home monitoring.

  6. Multi-Domain Machine Learning of VR-synchronised directional EEG phase connectivity reveals candidate Alzheimer's continuum biomarkers

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. Research Square 2026-07-23 Prevention trials

    Early, scalable detection of Alzheimer's disease (AD) and mild cognitive impairment (MCI) remains a global health priority, but non-invasive biomarkers that capture network-level dysfunction during standardized cognitive challenge remain limited.

  7. FastEBM: Fast, Scalable, and Uncertainty-Aware Event-Based Disease Progression Modeling

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. bioRxiv 2026-07-22 Brain scans and imaging

    Event-based models (EBMs) are used to infer ordering of biomarker alteration patterns with respect to disease progression.

  8. Predictive Models for Cognitive Decline Assessment

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. F1000Res 2026-07-22 Long-term cohort studies

    This study contributes to the healthcare field by demonstrating the potential of providing a fast, transparent, and affordable assessment system that is accessible to low-income populations and clinics with limited budget.

  9. Detecting Alzheimer’s Disease through Chinese Speech: A Contrast of Manual and Automatic Linguistic Feature Extraction

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. PsyArXiv 2026-07-14 Digital health tools

    Recent research has revealed that linguistic features are effective digital markers for the early detection of Alzheimer’s disease (AD).

  10. EcoXAI: Autonomous Agentic Ecosystem for Explainable Artificial Intelligence and Biomedical Discovery

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. bioRxiv 2026-07-13 Drug development

    EcoXAI replaces monolithic AI text interfaces with an autonomous execution-driven framework with specialized bioinformatics agents for delivering proactive, data-driven insights grounded in established biological knowledge.

  11. Early Prediction of Parkinson’s Disease Progression by Integrating Research Cohort and Real-World Data Using Knowledge-Anchored Graph Learning

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. medRxiv 2026-07-09 Digital health tools

    Parkinson’s disease (PD) progression is highly heterogeneous.

  12. Nonlinear Association of Length of Stay With In-Hospital Mortality in Alzheimer’s Disease Hospitalizations: Admission-Only vs Inpatient-Course Prediction Using Explainable Machine Learning

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. Preprints.org 2026-07-07 Clinical safety

    Among 11,377 AD hospitalizations, 600 in-hospital deaths occurred (5.27%).

  13. MCH-Guard: Multimodal Machine Learning Framework for Risk Stratification of Cerebral Microhemorrhage Risk in the Alzheimer’s Disease Neuroimaging Initiative

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. medRxiv 2026-06-22 Treatments

    MCH-Guard offers a flexible clinical decision-support tool for optimizing spontaneous MCH & ARIA surveillance.

  14. Automated quantification of cerebral microbleeds for ARIA-H monitoring in Aging and Alzheimer’s Disease: A multicenter deep learning validation

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. medRxiv 2026-05-26 Treatments

    We trained a self-configuring nnU-Net model for CMB segmentation in a hetero-geneous multicenter sample ( n =264), including 1.5T and 3T field strengths, SWI and T2*-GRE sequences, and community and clinical cohorts.

  15. Treatment Effects of Cholinesterase Inhibitors in Alzheimer’s Disease: a Causal Machine Learning Approach

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. medRxiv 2026-02-12 Treatments

    A bstract INTRODUCTION Treatment response in Alzheimer’s disease (AD) varies substantially across patients, yet no validated frameworks exist to estimate heterogeneous treatment effects (HTE) from observational data while controlling for confounding bias.

  16. Detecting Preclinical Alzheimer’s Disease Risk in Cognitively Normal Adults Using Speech Acoustics: Validation with Plasma p-Tau217 and APOE-ε4 Status

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. medRxiv 2026-01-16 Digital health tools

    Spontaneous speech acoustics capture p-tau217/APOE-defined AD risk despite preserved cognition, supporting speech as a scalable, biologically grounded biomarker for preclinical AD risk stratification.

  17. ATN Classification and Machine-Learned Plasma Biomarker Phenotypes Reveal Distinct Alzheimer’s Pathology in a Population-Based Cohort

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. medRxiv 2026-01-06 Biomarkers

    The analytic sample included 4,465 individuals (mean age 69.7±10.4 years; 58.7% female; 75.8% non-Hispanic White).

  18. Small-Sized Reasoning Language Models for Linguistic Screening of Alzheimer’s Disease

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. medRxiv 2026-01-01 Digital health tools

    Alzheimer’s disease (AD) is increasing in prevalence, and early detection is essential for timely care.

  19. Large Language Model-Driven Prioritization of Alzheimer’s Disease Drug Targets Across Multidimensional Criteria

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. medRxiv 2025-12-29 Digital health tools

    Large language models (LLMs) offer new opportunities to synthesize the vast and heterogeneous biomedical literature, yet their potential to support drug target prioritization in complex diseases such as Alzheimer’s disease (AD) remains largely unexplored.

  20. Investigating the Amyloid-Tau-Neurodegeneration Framework in Alzheimer’s Disease Using Semi-Supervised Multimodal Imaging Data Fusion

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. medRxiv 2025-12-15 Brain scans and imaging

    Semi-supervised multimodal fusion improves prediction and reveals interpretable imaging patterns that predict APOE4 and clinical diagnoses better than traditional approaches.

  21. Machine learning-based estimation of the mild cognitive impairment stage using multimodal physical and behavioral measures

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Scientific reports 2025-10-09 Cognitive tests and assessment

    Mild cognitive impairment (MCI) is a prodromal stage of dementia, and its early detection is critical for improving clinical outcomes.

  22. PLASMA-CYCLEGAN: PLASMA BIOMARKER-GUIDED MRI TO PET CROSS-MODALITY TRANSLATION USING CONDITIONAL CYCLEGAN

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Proceedings. IEEE International Symposium on Biomedical Imaging 2025-05-12 Biomarkers

    Cross-modality translation between MRI and PET imaging is challenging due to the distinct mechanisms underlying these modalities.

  23. Personalized Multi-Domain Digital Platform for Dementia Prevention

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Studies in health technology and informatics 2025-02-18 Prevention trials

    The Personalized Multi-Domain Digital Platform for Dementia Prevention (PM(DP)*2) is a conceptualized evidence-based initiative designed to reduce dementia burden through tailored interventions.

  24. Machine learning prediction of tau-PET in Alzheimer's disease using plasma, MRI, and clinical data

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2025-02 Biomarkers

    Models including plasma biomarkers yielded the most accurate predictions of tau-PET burden (best model: R-squared = 0.66-0.69), with especially high contribution from plasma phosphorylated tau-217 (p-tau217).

  25. A novel model for retinal imaging in the diagnosis of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. NPJ digital medicine 2025-01-09 Brain scans and imaging

    Alzheimer’s disease is the fifth-leading cause of death for adults over the age of 65.

  26. Use of Artificial Intelligence in Imaging Dementia

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Cells 2024-11-27 Treatments

    Alzheimer's disease is the most common cause of dementia in the elderly population (aged 65 years and over), followed by vascular dementia, Lewy body dementia, and rare types of neurodegenerative diseases, including frontotemporal dementia.

  27. Early detection of dementia through retinal imaging and trustworthy AI

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. NPJ digital medicine 2024-10-20 Brain scans and imaging

    Alzheimer's disease (AD) is a global healthcare challenge lacking a simple and affordable detection method.

  28. fMRI-based Alzheimer's disease detection via functional connectivity analysis: a systematic review

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. PeerJ. Computer science 2024-10-16 Brain scans and imaging

    Alzheimer's disease is a common brain disorder affecting many people worldwide.

  29. Color Fundus Photography and Deep Learning Applications in Alzheimer Disease

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Mayo Clinic proceedings. Digital health 2024-08-26 Brain scans and imaging

    The self-supervised ADRET model had superior accuracy when compared with ADVAS, in both UK Biobank (98.27% vs 77.20%; P<.001) and our institutional testing data sets (98.90% vs 94.17%; P=.04).

  30. Enhancing dementia risk screening with GAN-synthesized periodontal examination and general blood test data

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Frontiers in neurology 2024-08-14 Biomarkers

    This study used measured data from 108 participants and the synthesized data generated from the measured data.

  31. Deep learning-based amyloid PET harmonization to predict cognitive decline in non-demented elderly

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Radiology advances 2024-08-06 Brain scans and imaging

    DL-ADprob was independently prognostic in both ADNI-MCI (P < .001) and HABS-CU (P = .048) sets.

  32. Multimodal Retinal Imaging Classification for Parkinson's Disease Using a Convolutional Neural Network

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Translational vision science & technology 2024-08-01 Brain scans and imaging

    In total, 371 eyes of 249 control subjects and 75 eyes of 52 PD subjects were used for training, validation, and testing.

  33. Deep Learning Analysis of Retinal Structures and Risk Factors of Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2024-07 Brain scans and imaging

    The importance of early Alzheimer's Disease screening is becoming more apparent, given the fact that there is no way to revert the patient's status after the onset.

  34. Automatic offline-capable smartphone paper-based microfluidic device for efficient biomarker detection of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Analytica chimica acta 2024-04-06 Cognitive tests and assessment

    This paper introduces a new deep learning-assisted offline smartphone platform for early AD screening, offering rapid disease detection in low-resource areas.

  35. Interpreting artificial intelligence models: a systematic review on the application of LIME and SHAP in Alzheimer's disease detection

    ✓ Peer-reviewed alzhub usefulness score 72 out of 100. Brain informatics 2024-04-05 Digital health tools

    Explainable artificial intelligence (XAI) has gained much interest in recent years for its ability to explain the complex decision-making process of machine learning (ML) and deep learning (DL) models.

  36. Neuron-level explainable AI for Alzheimer's Disease assessment from fundus images

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Scientific reports 2024-04-02 Brain scans and imaging

    Alzheimer's Disease (AD) is a progressive neurodegenerative disease and the leading cause of dementia.

  37. Generating new drug repurposing hypotheses using disease-specific hypergraphs

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 2024 Drug development

    The drug development pipeline for a new compound can last 10-20 years and cost over $10 billion.

  38. Relationship Between Dementia and Systemic Metabolic Disorders

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Advances in experimental medicine and biology 2024 Biomarkers

    Recent research has linked systemic metabolic disorders to cognitive decline and dementia risk, including Alzheimer's. This is suspected to be due to lifestyle-related vascular impairments from atherosclerosis and other factors, such as malnutrition and anaemia.

  39. Speech-Based Digital Biomarkers for Alzheimer's Research

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Methods in molecular biology (Clifton, N.J.) 2024 Cognitive tests and assessment

    Digital biomarkers are of growing interest in the field of Alzheimer's Disease (AD) research.

  40. Organ aging signatures in the plasma proteome track health and disease

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Nature 2023-12-06 Biomarkers

    Animal studies show aging varies between individuals as well as between organs within an individual 1-4 , but whether this is true in humans and its effect on age-related diseases is unknown.

  41. Automatic Segmentation of Retinal Layers in Multiple Neurodegenerative Disorder Scenarios

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. IEEE journal of biomedical and health informatics 2023-11-07 Brain scans and imaging

    Retinal Optical Coherence Tomography (OCT) allows the non-invasive direct observation of the central nervous system, enabling the measurement and extraction of biomarkers from neural tissue that can be helpful in the assessment of ocular, systemic and Neurological Disorders (ND).

  42. Explainable variational autoencoder (E-VAE) model using genome-wide SNPs to predict dementia

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. Journal of biomedical informatics 2023-11-04 Genetics

    We obtained a predictive accuracy of 0.71 (95 % CI [0.59, 0.84]) with an AUC of 0.69 in the HRS test dataset and got an accuracy of 0.62 (95 % CI [0.56, 0.68]) with an AUC of 0.63 in the ROSMAP dataset.

  43. Blood biomarker-based classification study for neurodegenerative diseases

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Scientific reports 2023-10-11 Biomarkers

    As the population ages, neurodegenerative diseases are becoming more prevalent, making it crucial to comprehend the underlying disease mechanisms and identify biomarkers to allow for early diagnosis and effective screening for clinical trials.

  44. Artificial intelligence in the diagnosis of glaucoma and neurodegenerative diseases

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Clinical & experimental optometry 2023-09-06 Brain scans and imaging

    Artificial Intelligence is a rapidly expanding field within computer science that encompasses the emulation of human intelligence by machines.

  45. AD-BERT: Using pre-trained language model to predict the progression from mild cognitive impairment to Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Journal of biomedical informatics 2023-07-08 Digital health tools

    The use of EHRs for AD-related research is promising, and AD-BERT shows superior predictive performance in modeling MCI-to-AD progression prediction.

  46. Integrating Comorbidity Knowledge for Alzheimer's Disease Drug Repurposing using Multi-task Graph Neural Network

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science 2023-06-16 Drug development

    Alzheimer's Disease (AD) is a multifactorial disease that shares common etiologies with its multiple comorbidities, especially vascular diseases.

  47. SynthSR: A public AI tool to turn heterogeneous clinical brain scans into high-resolution T1-weighted images for 3D morphometry

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Science advances 2023-02-01 Digital health tools

    Every year, millions of brain magnetic resonance imaging (MRI) scans are acquired in hospitals across the world.

  48. Multiple Brain Tumor Classification with Dense CNN Architecture Using Brain MRI Images

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Life (Basel, Switzerland) 2023-01-28 Digital health tools

    Brain MR images are the most suitable method for detecting chronic nerve diseases such as brain tumors, strokes, dementia, and multiple sclerosis.

  49. Deep Reinforcement Learning-Based Retinal Imaging in Alzheimer's Disease: Potential and Perspectives

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Journal of Alzheimer's disease : JAD 2023 Brain scans and imaging

    Alzheimer's disease (AD) remains a global health challenge in the 21st century due to its increasing prevalence as the major cause of dementia.

  50. Development of digital voice biomarkers and associations with cognition, cerebrospinal biomarkers, and neural representation in early Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Alzheimer's & dementia (Amsterdam, Netherlands) 2023-01-01 Digital health tools

    These preliminary findings suggest that derived digital biomarkers may identify cognitive impairment in preclinical and prodromal AD, and may predict disease progression.

From across this tag

10 of the 205 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

All topic tags with their study counts