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283 results for "driving".

Research summaries 260

Showing the best 200 of 260, 51–60, page 6 of 20. Filter these by subject, year and score in the research library →

1. Air pollution: mechanisms of neuroinflammation and CNS diseaseResearch summary

   Research summaries · alzhub.org/study/air-pollution-mechanisms-of-neuroinflammation-and-cns-disease-19716187

   … health. While mechanisms driving air pollution-induced CNS pathology are poorly understood, new evidence suggests that microglial activation and changes in the blood-brain barrier are key components. Here we summarize recent …

2. Comparative mapping of single-cell transcriptomic landscapes in neurodegenerative diseasesResearch summary

   Research summaries · alzhub.org/study/comparative-mapping-of-single-cell-transcriptomic-landscapes-in-39764045

   … Potentially disease-driving neuronal cell subtypes were present in both PD and DLB. Cell-cell communication was predicted to be increased in AD but decreased in DLB and PD. DEGs were most commonly shared across NDDs within …

3. Dementia and caregiver burden: A three-year longitudinal studyResearch summary

   Research summaries · alzhub.org/study/dementia-and-caregiver-burden-a-three-year-longitudinal-study-31821606

   … medications, lack of driving ability-and female sex of caregivers were associated with greater burden. Conclusions High levels of caregiver burden are present in a large proportion of caregivers of people with dementia and this …

4. Environmental predictors of objectively measured out-of-home time among older adults with cognitive declineResearch summary

   Research summaries · alzhub.org/study/environmental-predictors-of-objectively-measured-out-of-home-time-30878823

   … (gender, age, education, driving status, fear of falling) were examined as potential predictors. After adjusting main effects of allocation group, time of measures, and their interactive effect, a mixed model showed that younger …

5. Examining Food Access Equity by Integrating Grocery Store Pricing into Spatial Accessibility MeasuresResearch summary

   Research summaries · alzhub.org/study/examining-food-access-equity-by-integrating-grocery-store-pricing-04a30932

   … more inequitable than driving to food stores and that African American and Hispanic minorities, the elderly, and carless households are more burdened than the reference groups (whites). Using our framework, we identify food …

6. Executive function and activities of daily living in Alzheimer's disease: a correlational meta-analysisResearch summary

   Research summaries · alzhub.org/study/executive-function-and-activities-of-daily-living-in-alzheimer-s-22572810

   … and one specific ADL, driving. Results Forty-nine studies met the inclusion criteria, and a total of 3,663 participants were included, the majority of whom were diagnosed with Alzheimer's disease. Most of the individual tests, …

7. Ibuprofen modulates inflammatory and autophagy-associated pathways linked to neurodegenerative pathology in APOE-context-dependent cellular modelsResearch summary

   Research summaries · alzhub.org/study/ibuprofen-modulates-inflammatory-and-autophagy-associated-pathways-e38b6498

   … solely dependent on the driving power of the immune cytokine interleukin-1 beta (IL-1β), arising from neuronal distress and release of sAPPα, which activates microglia for synthesis and release of IL-1β driving synthesis of βAPP, …

8. Navigation expertise and the human hippocampus: a structural brain imaging analysisResearch summary

   Research summaries · alzhub.org/study/navigation-expertise-and-the-human-hippocampus-a-structural-brain-12699332

   … with time spent taxi driving (E.A. Maguire et al., 2000. Proc Natl Acad Sci USA 97: 4398-4403). This change suggests that increased posterior hippocampal grey matter volume is acquired in response to increased taxi driving …

9. Neurobiology of dementiaResearch summary

   Research summaries · alzhub.org/study/neurobiology-of-dementia-86818921

   … these processes are driving the development of biomarkers and disease-modifying therapies, paving the way for more precise, personalized approaches to diagnosis and care. This chapter describes dementia as a multifactorial …

10. Neuropathology of dementia in Parkinson's disease: a prospective, community-based studyResearch summary

    Research summaries · alzhub.org/study/neuropathology-of-dementia-in-parkinson-s-disease-a-prospective-16240351

    … is the main substrate driving the progression of cognitive impairment in Parkinson's disease. The Lewy body score and Braak and Braak stage were significantly associated with the rate of cognitive decline, but only the Lewy body …

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