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283 results for "driving".
Research summaries 260
Showing the best 200 of 260, 41–50, page 5 of 20. Filter these by subject, year and score in the research library →
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In vivo and in vitro evidence supporting a role for the inflammatory cytokine interleukin-1 as a driving force in Alzheimer pathogenesisResearch summary
Research summaries · alzhub.org/study/in-vivo-and-in-vitro-evidence-supporting-a-role-for-the-inflammatory-8892349
Interleukin-1 (IL-1), an inflammatory cytokine overexpressed in the neuritic plaques of Alzheimer's disease, activates astrocytes and enhances production and processing of beta-amyloid precursor protein (beta-APP). Activated …
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Drivers with dementia: Forecasting the futureResearch summary
Research summaries · alzhub.org/study/drivers-with-dementia-forecasting-the-future-40462620
BackgroundA decline in driving skills is well documented in people with dementia.ObjectiveTo provide a current estimate and future forecast of drivers with dementia in Ontario, Canada, taking into account sex differences and …
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A longitudinal study of drivers with Alzheimer diseaseResearch summary
Research summaries · alzhub.org/study/a-longitudinal-study-of-drivers-with-alzheimer-disease-18216302
… natural progression of driving impairment in persons who initially have very mild to mild dementia. Methods We studied 128 older drivers, including 84 with early Alzheimer disease (AD) and 44 age-matched control subjects without …
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Motor vehicle crashes in dementia of the Alzheimer typeResearch summary
Research summaries · alzhub.org/study/motor-vehicle-crashes-in-dementia-of-the-alzheimer-type-3207361
… crash while they were driving, whereas only 10% of the control subjects had had a crash in the previous 5 years. The odds ratio for crashes in the DAT group was 7.9 (p less than 0.01). Moreover, in 77% of DAT patients, a …
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Reliability of the Washington University Road Test. A performance-based assessment for drivers with dementia of the Alzheimer typeResearch summary
Research summaries · alzhub.org/study/reliability-of-the-washington-university-road-test-a-performance-9193205
… controls in which subjects' driving performance was evaluated by several raters in an initial and a follow-up road test. Setting Urban medical school and urban highways and streets. Subjects A convenience sample of 58 controls, …
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The older adult driver with cognitive impairment: "It's a very frustrating life"Research summary
Research summaries · alzhub.org/study/the-older-adult-driver-with-cognitive-impairment-it-s-a-very-20424254
… severity in relation to driving, no consensus on the assessment of older drivers with cognitive impairment, and no gold standard for determining driving fitness. Yet clinicians are called on by patients, their families, other …
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Identifying and Predicting Cognitive Decline Using Multi-Modal Sensor Data and Machine Learning ApproachResearch summary
Research summaries · alzhub.org/study/identifying-and-predicting-cognitive-decline-using-multi-modal-sensor-40585273
… incorporating demographics and driving features, and prediction performance (accuracy = 70.48%; precision = 71.88%; F1-score = 74.80%, recall = 77.97%). Our results demonstrate that the multi-modal classifier achieved strong …
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Simulated car crashes and crash predictors in drivers with Alzheimer diseaseResearch summary
Research summaries · alzhub.org/study/simulated-car-crashes-and-crash-predictors-in-drivers-with-alzheimer-9152111
… crucial to the task of driving. Rational decisions about whether such impaired individuals should continue to drive require objective assessments of driver performance. Objective To measure relevant performance factors using …
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The Cochrane Database of Systematic Reviews – Issue 4 2008Research summary
Research summaries · alzhub.org/study/the-cochrane-database-of-systematic-reviews-issue-4-2008-36b8f4be
… preventing alcohol-impaired driving and an updated review comparing the effects of a policy of ‘hospital at home’ versus inpatient care. More than 3500 Cochrane Reviews are now available in full, including information on the …
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omicSynth: An open multi-omic community resource for identifying druggable targets across neurodegenerative diseasesResearch summary
Research summaries · alzhub.org/study/omicsynth-an-open-multi-omic-community-resource-for-identifying-38181731
… biological mechanisms in driving discovery and creating disease modifying therapies. The global population is aging, driving an urgent need for therapeutics that stop disease progression and eliminate symptoms. In this study, we …
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