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199 results for "antipsychotic".

Research summaries 180

Showing 31–40, page 4 of 18. Filter these by subject, year and score in the research library →

1. Efficacy and comparative effectiveness of atypical antipsychotic medications for off-label uses in adults: a systematic review and meta-analysisResearch summary

   Research summaries · alzhub.org/study/efficacy-and-comparative-effectiveness-of-atypical-antipsychotic-21954480

   Among 14 placebo-controlled trials of elderly patients with dementia reporting a total global outcome score that includes symptoms such as psychosis, mood alterations, and aggression, small but statistically significant effects …

2. Antipsychotic therapy and short-term serious events in older adults with dementiaResearch summary

   Research summaries · alzhub.org/study/antipsychotic-therapy-and-short-term-serious-events-in-older-adults-18504337

   Background Antipsychotic therapy is widely used to treat behavioral problems in older adults with dementia. Cohort studies evaluating the safety of antipsychotic therapy generally focus on a single adverse event. We compared the …

3. Rural and urban differences in quality of dementia care of persons with dementia and caregivers across all domains: a systematic reviewResearch summary

   Research summaries · alzhub.org/study/rural-and-urban-differences-in-quality-of-dementia-care-of-persons-36721162

   … (Integration), higher antipsychotic medications (Safety), lower use of home care services and higher use of nursing home (Patient-Centered Care) compared to urban persons with dementia. Conclusions This comprehensive portrait of …

4. Cost-benefit analysis of second-generation antipsychotics and placebo in a randomized trial of the treatment of psychosis and aggression in Alzheimer diseaseResearch summary

   Research summaries · alzhub.org/study/cost-benefit-analysis-of-second-generation-antipsychotics-and-placebo-17984395

   Context Second-generation antipsychotics (SGAs) are prescribed for psychosis, aggression, and agitation in Alzheimer disease (AD). Objective To conduct a cost-benefit analysis of SGAs and placebo (taken to represent a "watchful …

5. Second-Generation Antipsychotics and Tardive Syndromes in Affective Illness: A Public Health Problem With Neuropsychiatric ConsequencesResearch summary

   Research summaries · alzhub.org/study/second-generation-antipsychotics-and-tardive-syndromes-in-affective-e319eb2f

   … for second-generation antipsychotics in affective illness. Package inserts label tardive syndromes “potentially reversible” while uniformly omitting patient counseling for long-term neurodegenerative side effects. I found that …

6. Use of antipsychotics among elderly nursing home residents with dementia in the US: an analysis of National Survey DataResearch summary

   Research summaries · alzhub.org/study/use-of-antipsychotics-among-elderly-nursing-home-residents-with-19591523

   … examine utilization of antipsychotic medications and the factors associated with use of atypical antipsychotics among elderly nursing home residents with dementia. Multiple logistic regression analysis within the conceptual …

7. The dementia antipsychotic withdrawal trial (DART-AD): long-term follow-up of a randomised placebo-controlled trialResearch summary

   Research summaries · alzhub.org/study/the-dementia-antipsychotic-withdrawal-trial-dart-ad-long-term-follow-19138567

   We aimed to assess whether continued treatment with antipsychotics in people with AD is associated with an increased risk of mortality. There was a reduction in survival in the patients who continued to receive antipsychotics …

8. Behavioral and Psychological Symptoms of Dementia: How Long Does Every Behavior Last, and Are Particular Behaviors Associated With PRN Antipsychotic Agent Use?Research summary

   Research summaries · alzhub.org/study/behavioral-and-psychological-symptoms-of-dementia-how-long-does-every-f2ae00d2

   … Associated With PRN Antipsychotic Agent Use?” found on pages 22–37, carefully noting any tables and other illustrative materials that are included to enhance your knowledge and understanding of the content. Identify which BPSD …

9. Reducing antipsychotic drug use in nursing homes. A controlled trial of provider educationResearch summary

   Research summaries · alzhub.org/study/reducing-antipsychotic-drug-use-in-nursing-homes-a-controlled-trial-8447709

   … home residents receive antipsychotic drugs, primarily for the behavioral manifestations of dementia. This high level of use of drugs with substantial toxicity has engendered a strong and persistent controversy and recently has …

10. Atypical antipsychotic use in patients with dementia: managing safety concernsResearch summary

    Research summaries · alzhub.org/study/atypical-antipsychotic-use-in-patients-with-dementia-managing-safety-22952071

    … strongest for atypical antipsychotics, but these agents must be used with great caution. Adverse effects in patients with dementia include an increased risk of mortality and cerebrovascular events, as well as metabolic effects, …

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