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315 results for "driving".

Research summaries 292

Showing the best 200 of 292, 21–30, page 3 of 20. Filter these by subject, year and score in the research library →

  1. The drive-wise project: driving simulator training increases real driving performance in healthy older driversResearch summary

    Research summaries · alzhub.org/study/the-drive-wise-project-driving-simulator-training-increases-real-24860497

    … associated with unsafe driving behavior. We hypothesized that 10 active training sessions in a driving simulator increase cognitive and on-road driving performance. In addition, driving simulator training should outperform …

  2. Depression and Alzheimer's Disease Biomarkers Predict Driving DeclineResearch summary

    Research summaries · alzhub.org/study/depression-and-alzheimer-s-disease-biomarkers-predict-driving-decline-30400098

    … were associated with driving performance on the road test (p≤0.05, HR = 2.51-3.15). In the CSF ptau181 model, depression diagnosis (p = 0.031, HR = 2.51) and antidepressant use (p = 0.037, HR = 2.50) were statistically …

  3. Practice parameter: risk of driving and Alzheimer's disease (an evidence-based review) [RETIRED]: report of the quality standards subcommittee of the American Academy of NeurologyResearch summary

    Research summaries · alzhub.org/study/practice-parameter-risk-of-driving-and-alzheimer-s-disease-an-10881240

    … parameter regarding driving and AD the authors performed a systematic review of the literature. The authors identified well-designed, controlled studies of driving and AD using the National Library of Medicine's MEDLINE database. …

  4. Amyloid Imaging, Cerebrospinal Fluid Biomarkers Predict Driving Performance Among Cognitively Normal IndividualsResearch summary

    Research summaries · alzhub.org/study/amyloid-imaging-cerebrospinal-fluid-biomarkers-predict-driving-27128959

    … biomarkers are related to driving performance among cognitively normal older adults. Individuals with normal cognition, aged 65+ years, and driving at least once per week, were recruited. Participants (N=129) took part in …

  5. Beyond the synucleinopathies: alpha synuclein as a driving force in neurodegenerative comorbiditiesResearch summary

    Research summaries · alzhub.org/study/beyond-the-synucleinopathies-alpha-synuclein-as-a-driving-force-in-31508228

    … be a key protein in driving the pathogenic processes in neurodegenerative comorbidities. In addition to reviewing the frequency of concomitant deposition of aSyn in the neurodegenerative proteinopathies, we also consider our …

  6. Oxidized cholesterol as the driving force behind the development of Alzheimer's diseaseResearch summary

    Research summaries · alzhub.org/study/oxidized-cholesterol-as-the-driving-force-behind-the-development-of-26150787

    Alzheimer's disease (AD), the most common neurodegenerative disorder associated with dementia, is typified by the pathological accumulation of amyloid Aβ peptides and neurofibrillary tangles (NFT) within the brain. Considerable …

  7. Vasomotion as a Driving Force for Paravascular Clearance in the Awake Mouse BrainResearch summary

    Research summaries · alzhub.org/study/vasomotion-as-a-driving-force-for-paravascular-clearance-in-the-awake-31810839

    … (CAA). However, the major driving force for clearance remains largely unknown. Here we used in vivo two-photon microscopy in awake head-fixed mice to assess the role of spontaneous vasomotion in paravascular clearance. Vasomotion …

  8. Proteomics and <i>C9orf72</i> neuropathology identify ribosomes as poly-GR/PR interactors driving toxicityResearch summary

    Research summaries · alzhub.org/study/proteomics-and-i-c9orf72-i-neuropathology-identify-ribosomes-as-poly-30456350

    … ribosome biogenesis may be driving the acute toxicity observed in vitro. In patients, only ribosomes and STAU2 co-aggregated with poly-GR/PR. Partial sequestration of ribosomes may chronically impair protein synthesis even in the …

  9. Single-cell analysis reveals inflammatory interactions driving macular degenerationResearch summary

    Research summaries · alzhub.org/study/single-cell-analysis-reveals-inflammatory-interactions-driving-37147305

    Due to commonalities in pathophysiology, age-related macular degeneration (AMD) represents a uniquely accessible model to investigate therapies for neurodegenerative diseases, leading us to examine whether pathways of disease …

  10. Inflammation and cerebral small vessel disease: A systematic reviewResearch summary

    Research summaries · alzhub.org/study/inflammation-and-cerebral-small-vessel-disease-a-systematic-review-31181331

    … blood-brain barrier may be a driving force behind SVD. Conversely, cross-sectional findings on systemic inflammation were mixed, although longitudinal investigations demonstrated that elevated levels of systemic inflammatory …

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