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315 results for "driving".

Research summaries 292

Showing the best 200 of 292, 91–100, page 10 of 20. Filter these by subject, year and score in the research library →

1. Finding the falsification threshold of the toxic proteinopathy hypothesis in neurodegenerationResearch summary

   Research summaries · alzhub.org/study/finding-the-falsification-threshold-of-the-toxic-proteinopathy-36796939

   … trials as falsifying the driving hypotheses, in particular if the desirable change in surrogate endpoints has been achieved. We propose four steps to refute a hypothesis in future-negative surrogate-backed trials and argue that …

2. Genetic and epigenetic targets of natural dietary compounds as anti-Alzheimer's agentsResearch summary

   Research summaries · alzhub.org/study/genetic-and-epigenetic-targets-of-natural-dietary-compounds-as-anti-37843220

   … pathophysiological mechanisms driving Alzheimer's disease are interfaced with epigenetic dysregulation. However, the dynamic nature of epigenetics seems to open up new avenues and hope in regenerative neurogenesis to improve …

3. Gut microbiome-targeted therapies for Alzheimer's diseaseResearch summary

   Research summaries · alzhub.org/study/gut-microbiome-targeted-therapies-for-alzheimer-s-disease-37934614

   … of gut microbiota in driving AD progression, and the successes and challenges of implementing available gut microbiome-targeted therapies (including probiotics, prebiotics, synbiotics, postbiotics, and fecal microbiota …

4. In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome RecruitmentResearch summary

   Research summaries · alzhub.org/study/in-situ-structure-of-neuronal-c9orf72-poly-ga-aggregates-reveals-29398115

   … neuronal proteostasis by driving the accumulation and functional impairment of a large fraction of cellular proteasomes. Using cryo-electron tomography in intact neurons, this study found that poly-GA aggregates from the C9orf72 …

5. LiveDrive AI: A Pilot Study of a Machine Learning-Powered Diagnostic System for Real-Time, Non-Invasive Detection of Mild Cognitive ImpairmentResearch summary

   Research summaries · alzhub.org/study/livedrive-ai-a-pilot-study-of-a-machine-learning-powered-diagnostic-39851360

   … these gaps by exploring driving performance as a novel, non-invasive biomarker for MCI detection. Using the LiveDrive AI system, equipped with multimodal sensing (MMS) technology and a driving performance assessment strategy, the …

6. Parkinson's Disease: The Epidemiology, Risk Factors, Molecular Pathogenesis, Prevention, and TherapyResearch summary

   Research summaries · alzhub.org/study/parkinson-s-disease-the-epidemiology-risk-factors-molecular-41394959

   … understanding of the mechanisms driving α‑synuclein aggregation and disease progression. This review provides an integrated overview of PD across epidemiological, etiological, pathophysiological, and clinical dimensions. It …

7. Acceptable standards for clinic‐based digital cognitive assessments: Recommendations from the Global CEO Initiative on Alzheimer's DiseaseResearch summary

   Research summaries · alzhub.org/study/acceptable-standards-for-clinicbased-digital-cognitive-assessments-41405443

   … persistent underdiagnosis, is driving an increased need for scalable cognitive assessment tools. Digital cognitive assessments (DCAs) offer a promising solution by addressing longstanding barriers to routine cognitive testing and …

8. Aging and Hearing Health: The Life-course ApproachResearch summary

   Research summaries · alzhub.org/study/aging-and-hearing-health-the-life-course-approach-26994265

   … of autonomy, impaired driving ability, and financial decline. Furthermore, the onset of hearing loss is gradual and subtle, first affecting the detection of high-pitched sounds and with difficulty understanding speech in noisy …

9. Artificial Intelligence in the Diagnostic Use of Transcranial Doppler and Sonography: A Scoping Review of Current Applications and Future DirectionsResearch summary

   Research summaries · alzhub.org/study/artificial-intelligence-in-the-diagnostic-use-of-transcranial-doppler-40722373

   … diagnostic imaging, driving advancements in personalized medicine and improving patient outcomes. This review highlights the critical role of interdisciplinary collaboration in achieving these goals, exploring the current …

10. Associations of Longitudinal Changes in Blood Biomarkers of Dementia With the Proportion of Genetically Inferred African AncestryResearch summary

    Research summaries · alzhub.org/study/associations-of-longitudinal-changes-in-blood-biomarkers-of-dementia-40779734

    … across ancestry and the driving biological or sociocultural factors. In this African American cohort, a higher proportion of genetically inferred African ancestry was suggestively linked to a slower rise in blood p-Tau181 over …

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