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Every row of the evidence table
One row per finding: what was tested, which way the result went, and how the study was built. The answer by area, and where the studies disagree, are on the main page.
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Showing 2 of 382 rows. One row per study per exposure: a study that tested two different things appears twice, once for each.
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| Exposure | Question | Direction | Outcome measured | Design | People | Effect size, as the source reported it | Source |
|---|---|---|---|---|---|---|---|
| Health-system and payment model Care, carers and services | Treatment |
No direction reported
whyA single-programme implementation report with no comparison group. It counts enrolment and service use and estimates no effect. |
Enrolment, respite use and disenrolment in the first year of one GUIDE programme | cohort study | 158 | Over 35% of eligible beneficiaries have utilized respite services. Approximately 9% have disenrolled, the majority (64%) expired/hospice |
Innovation in Aging (GSA 2025 conference abstract)
2025 ⚠ Conference abstract — not peer-reviewed DOI 10.1093/geroni/igaf122.3561 |
| MRI amygdalar atrophy scale (marker of LATE) Care, carers and services | Treatment |
No direction reported
whyA classification-validation study without a neuropathological reference standard, so accuracy cannot be judged. The groups behaved as expected: patients labelled LATE had mild amnestic impairment, limbic atrophy and stable MMSE over 30 months, while AD and AD/LATE groups declined. |
Clinical, imaging and 30-month cognitive profiles of memory-clinic patients classified as LATE, AD, AD/LATE or neither by the amygdalar atrophy scale plus AD biomarkers | cohort study | 469 | the LATE group maintained cognitive stability as the No-AD/No-LATE group (β = -0.010, 95% CI -0.096 to 0.075, p = 0.813), whereas both AD (β = -0.136, 95% CI -0.184 to -0.088, p < 0.001) and AD/LATE (β = -0.139, 95% CI -0.196 to -0.082, p < 0.001) groups showed faster decline over time |
Neurology
2026 ✓ Peer-reviewed PMID 41428981 |