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283 results for "driving".

Research summaries 260

Showing the best 200 of 260, 31–40, page 4 of 20. Filter these by subject, year and score in the research library →

  1. Improving quality of life for institutionalized individuals with advanced dementia: A pilot study on efficacy of a semi-immersive virtual reality driving simulator for individuals with advanced dementiaResearch summary

    Research summaries · alzhub.org/study/improving-quality-of-life-for-institutionalized-individuals-with-940f3080

    • A novel semi-immersive VR driving simulator (VRDS) for institutionalized older adults with advanced dementia. • The VRDS integrates realistic driving with a virtual environment to stimulate implicit memory and improve cognitive …

  2. Beyond the synucleinopathies: alpha synuclein as a driving force in neurodegenerative comorbiditiesResearch summary

    Research summaries · alzhub.org/study/beyond-the-synucleinopathies-alpha-synuclein-as-a-driving-force-in-31508228

    … be a key protein in driving the pathogenic processes in neurodegenerative comorbidities. In addition to reviewing the frequency of concomitant deposition of aSyn in the neurodegenerative proteinopathies, we also consider our …

  3. The Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat): Driving Multicentric Research and Implementation ScienceResearch summary

    Research summaries · alzhub.org/study/the-multi-partner-consortium-to-expand-dementia-research-in-latin-33776890

    … and economic factors driving the presentation of frontotemporal dementia and Alzheimer's disease in Latin America relative to the US. We describe ongoing ReDLat studies in various fields and ongoing research extensions. Then, we …

  4. The effects of driving cessation on the elderly with dementia and their caregiversResearch summary

    Research summaries · alzhub.org/study/the-effects-of-driving-cessation-on-the-elderly-with-dementia-and-11426682

    This research explores how the loss of driving privileges by impaired drivers affects households. The particular focus is on the travel behavior and preceptions of people living in households where an elderly driver has had his …

  5. Microglia-Derived Extracellular Vesicles from Alzheimer’s Disease Patients Carry miRNAs Driving a Neuroinflammatory ResponseResearch summary

    Research summaries · alzhub.org/study/microglia-derived-extracellular-vesicles-from-alzheimers-disease-41678018

    … these cells, thereby driving a neuroinflammatory response. Taken together, putatively microglia-derived EVs from the CSF of AD patients contain miRNAs, which are capable of activating hTLR8 and inducing an inflammatory response …

  6. Single-cell analysis reveals inflammatory interactions driving macular degenerationResearch summary

    Research summaries · alzhub.org/study/single-cell-analysis-reveals-inflammatory-interactions-driving-37147305

    Due to commonalities in pathophysiology, age-related macular degeneration (AMD) represents a uniquely accessible model to investigate therapies for neurodegenerative diseases, leading us to examine whether pathways of disease …

  7. Endo-lysosomal and autophagic dysfunction: a driving factor in Alzheimer's disease?Research summary

    Research summaries · alzhub.org/study/endo-lysosomal-and-autophagic-dysfunction-a-driving-factor-in-28027395

    Alzheimer's disease (AD) is the most common cause of dementia, and its prevalence will increase significantly in the coming decades. Although important progress has been made, fundamental pathogenic mechanisms as well as most …

  8. Oxidized cholesterol as the driving force behind the development of Alzheimer's diseaseResearch summary

    Research summaries · alzhub.org/study/oxidized-cholesterol-as-the-driving-force-behind-the-development-of-26150787

    Alzheimer's disease (AD), the most common neurodegenerative disorder associated with dementia, is typified by the pathological accumulation of amyloid Aβ peptides and neurofibrillary tangles (NFT) within the brain. Considerable …

  9. p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)Research summary

    Research summaries · alzhub.org/study/p53-is-a-central-regulator-driving-neurodegeneration-caused-by-33482083

    The most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) is a GGGGCC repeat expansion in the C9orf72 gene. We developed a platform to interrogate the chromatin accessibility landscape …

  10. Monomeric C-reactive protein--a key molecule driving development of Alzheimer's disease associated with brain ischaemia?Research summary

    Research summaries · alzhub.org/study/monomeric-c-reactive-protein-a-key-molecule-driving-development-of-26335098

    Alzheimer's disease (AD) increases dramatically in patients with ischaemic stroke. Monomeric C-reactive protein (mCRP) appears in the ECM of ischaemic tissue after stroke, associating with microvasculature, neurons and …

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