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292 results for "driving".

Research summaries 269

Showing the best 200 of 269, 181–190, page 19 of 20. Filter these by subject, year and score in the research library →

1. Epidemiology of dementias and Alzheimer's diseaseResearch summary

   Research summaries · alzhub.org/study/epidemiology-of-dementias-and-alzheimer-s-disease-23159715

   … consequences. It is driving the current epidemic of dementia, both in terms of its extent and global distribution. The aim of the study was to summarize recent findings relevant to the epidemiological knowledge of dementia and …

2. Haptoglobin interacts with apolipoprotein E and beta-amyloid and influences their crosstalkResearch summary

   Research summaries · alzhub.org/study/haptoglobin-interacts-with-apolipoprotein-e-and-beta-amyloid-and-25058565

   Beta-amyloid accumulation in brain is a driving force for Alzheimer's disease pathogenesis. Apolipoprotein E (ApoE) represents a critical player in beta-amyloid homeostasis, but its role in disease progression is controversial. …

3. Health Care Costs Associated With Hospice Use For People With Dementia In The USResearch summary

   Research summaries · alzhub.org/study/health-care-costs-associated-with-hospice-use-for-people-with-37669483

   … people with dementia is driving up costs. Yet this perspective fails to incorporate potential cost savings associated with hospice. We estimated the association between hospice use by people with dementia and health care costs, …

4. Hemispheric asymmetry of tau pathology is related to asymmetric amyloid deposition in Alzheimer's DiseaseResearch summary

   Research summaries · alzhub.org/study/hemispheric-asymmetry-of-tau-pathology-is-related-to-asymmetric-40913038

   … However, the factors driving this asymmetry remain poorly understood. Here we explore whether tau asymmetry is linked to i) reduced inter-hemispheric brain connectivity (potentially restricting tau spread), or ii) asymmetry in …

5. Increased Use of an Expensive, Elective Procedure: Total Hip Replacements in the 1980sResearch summary

   Research summaries · alzhub.org/study/increased-use-of-an-expensive-elective-procedure-total-hip-8326773

   … of the major forces driving national health care costs. This study assumes that treatment choices are made by (or for) each patient to maximize expected net benefits. Within this framework, the use of THR might have increased …

6. Increased dosage of Dyrk1A alters alternative splicing factor (ASF)-regulated alternative splicing of tau in Down syndromeResearch summary

   Research summaries · alzhub.org/study/increased-dosage-of-dyrk1a-alters-alternative-splicing-factor-asf-18658135

   … Ser-234, and Ser-238, driving it into nuclear speckles and preventing it from facilitating tau exon 10 inclusion. The increased dosage of Dyrk1A in DS brain due to trisomy of chromosome 21 correlates to an increase in 3R-tau …

7. Inflammation in Neurological Disorders: The Thin Boundary Between Brain and PeripheryResearch summary

   Research summaries · alzhub.org/study/inflammation-in-neurological-disorders-the-thin-boundary-between-32143546

   … phenomenon sparking and driving the neuropathological processes. However, the upstream/downstream relationship between inflammatory events and neurological pathology is still unclear. Recent Advances: Solid recent evidence …

8. Interplay among gut microbiota, intestinal mucosal barrier and enteric neuro-immune system: a common path to neurodegenerative diseases?Research summary

   Research summaries · alzhub.org/study/interplay-among-gut-microbiota-intestinal-mucosal-barrier-and-enteric-29797112

   … represent a common path driving the onset of the main neurodegenerative diseases, even though each disease displays its own distinct clinical features. Neurological diseases, such as Parkinson's disease, Alzheimer's disease, …

9. Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's diseaseResearch summary

   Research summaries · alzhub.org/study/lipopolysaccharide-induced-inflammation-exacerbates-tau-pathology-by-16192374

   … a pivotal role as a driving force that can modulate the neuropathology. Here, we characterized the time course of microglia activation in the brains of a transgenic model of AD (3xTg-AD) and discerned its relationship to the …

10. Local delivery of protease-resistant stromal cell derived factor-1 for stem cell recruitment after myocardial infarctionResearch summary

    Research summaries · alzhub.org/study/local-delivery-of-protease-resistant-stromal-cell-derived-factor-1-17875967

    … data demonstrate that driving chemotaxis of stem cells by local chemokine delivery is a promising new strategy for tissue regeneration. Methods and results We designed a new chemokine called S-SDF-1(S4V) that is resistant to …

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