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290 results for "driving".

Research summaries 267

Showing the best 200 of 267, 151–160, page 16 of 20. Filter these by subject, year and score in the research library →

1. Out of Pocket Costs for People with Dementia: A Comparison Across Insurance TypesResearch summary

   Research summaries · alzhub.org/study/out-of-pocket-costs-for-people-with-dementia-a-comparison-across-51811bdb

   … types of healthcare driving out-of-pocket costs for people with dementia. We conducted a cohort study of PWD age 65+ in the Medicare Current Beneficiary Survey, 2002-2022. We categorized PWD based on 12 months of TM, MA, partial …

2. Single-nucleus multi-omics identifies shared and distinct pathways in Pick's and Alzheimer's diseaseResearch summary

   Research summaries · alzhub.org/study/single-nucleus-multi-omics-identifies-shared-and-distinct-pathways-in-41223260

   … critical regulatory changes driving disease progression, revealing potential therapeutic targets. Our comparative analyses uncovered disease-enriched noncoding regions and genome-wide transcription factor (TF) binding …

3. Structural and social determinants of dementia risk among adults racialized as Black: Results from a community‐based system dynamics approachResearch summary

   Research summaries · alzhub.org/study/structural-and-social-determinants-of-dementia-risk-among-adults-40684246

   … and mental healthcare, driving dementia risk. Those from more deprived areas highlighted the need for improved health education, public transportation, healthcare access, and job opportunities. Addressing dementia disparities …

4. TREM2 promotes lung fibrosis via controlling alveolar macrophage survival and pro-fibrotic activityResearch summary

   Research summaries · alzhub.org/study/trem2-promotes-lung-fibrosis-via-controlling-alveolar-macrophage-39971937

   … alveolar macrophages driving disease progression. However, the mechanisms regulating their pro-fibrotic behavior and survival remain unclear, and effective therapeutic strategies are lacking. Here we show that triggering …

5. The Effectiveness of Vitamin E Treatment in Alzheimer's DiseaseResearch summary

   Research summaries · alzhub.org/study/the-effectiveness-of-vitamin-e-treatment-in-alzheimer-s-disease-30781638

   … hypocholesterolemic properties, driving to its importance for brain health. Moreover, the levels of vitamin E in Alzheimer's disease patients are lower than in non-demented controls. Thus, vitamin E could be a good candidate to …

6. The burden of disease in older people and implications for health policy and practiceResearch summary

   Research summaries · alzhub.org/study/the-burden-of-disease-in-older-people-and-implications-for-health-25468153

   … population ageing is driving the worldwide epidemic of chronic diseases, substantial untapped potential exists to modify the relation between chronological age and health. This objective is especially important for the most …

7. The role of NLRP3-CASP1 in inflammasome-mediated neuroinflammation and autophagy dysfunction in manganese-induced, hippocampal-dependent impairment of learning and memory abilityResearch summary

   Research summaries · alzhub.org/study/the-role-of-nlrp3-casp1-in-inflammasome-mediated-neuroinflammation-28318352

   … However, the mechanism driving these phenomena remains poorly understood. We demonstrate that Mn activates the NLRP3-CASP1 inflammasome pathway in the hippocampus of mice and BV2 cells by triggering autophagy-lysosomal …

8. There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALSResearch summary

   Research summaries · alzhub.org/study/there-has-been-an-awakening-emerging-mechanisms-of-c9orf72-mutations-27059391

   … are most important for driving disease and therefore most critical for considering during the development of therapeutic interventions. This article is part of a Special Issue entitled SI:RNA Metabolism in Disease. Three major …

9. Towards Combinatorial Approaches for Preserving Cognitive Fitness in AgingResearch summary

   Research summaries · alzhub.org/study/towards-combinatorial-approaches-for-preserving-cognitive-fitness-in-30343822

   … ultimately converge in driving neurotrophic signaling. Considering recent technological advances, several interventions apart from cognitive enhancing drugs, including noninvasive brain stimulation, physical exercise/vascular …

10. APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloidResearch summary

    Research summaries · alzhub.org/study/apoe4-exacerbates-synuclein-pathology-and-related-toxicity-32024798

    … Alzheimer's disease mainly by driving amyloid-β pathology. Recently, APOE4 has also been found to be a genetic risk factor for Lewy body dementia (LBD), which includes dementia with Lewy bodies and Parkinson's disease dementia. …

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