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Home › Research › What the research found › Every row

Every row of the evidence table

One row per finding: what was tested, which way the result went, and how the study was built. The answer by area, and where the studies disagree, are on the main page.

Every row

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Area All 382 Care, carers and services 140 Medicines 85 Genes (not modifiable) 35 All modifiable factors together 27 Diet and supplements 23 Exercise and activity 21 Sleep, mood and social life 19 Hearing and vision 8 Alcohol, tobacco and cannabis 6 Infection and vaccination 5 Heart and metabolic health 4 Injury, delirium and falls 4 Environment 3 Cognitive activity 2
Question Both Prevention 190 Treatment 192
Direction Any Benefit 144 Harm 105 No effect 38 Mixed 37 No direction reported 58
Design Any meta-analysis 57 randomised trial 44 phase 3 trial 15 systematic review 9 phase 2 trial 10 cohort study 136 phase 1 trial 2 cross-sectional study 31 case-control study 14 modelling study 20 regulatory decision 7 company announcement 1 coverage determination 1 None 35
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Showing 3 of 382 rows. One row per study per exposure: a study that tested two different things appears twice, once for each.

Scroll the table sideways to see every column.

Research and outcomes, 3 rows. Every row links to its source.
Exposure Question Direction Outcome measured Design People Effect size, as the source reported it Source
Anti-amyloid antibody Medicines Treatment No direction reported
why

Mechanistic multi-omic profiling of blood from three ARIA-positive patients and three matched controls on lecanemab. It describes a clonally expanded cytotoxic CD8+ T-cell signature and estimates no clinical effect.

 Peripheral CD8+ T-cell signature in lecanemab-associated ARIA case-control study 6 not established — pubmed abstract reports no numeric effect size. Nature Communications 2026
✓ Peer-reviewed PMID 41617706
Anticholinergic / benzodiazepine burden Medicines Treatment Harm 180-day mortality case-control study 139,103 180-day mortality HR 1.41 (95% CI 1.38-1.44) for benzodiazepines; HR 1.16 (95% CI 1.12-1.20) for antipsychotics JAMA Network Open 2025
✓ Peer-reviewed PMID 41085983
Antipsychotics (harms / discontinuation) Medicines Treatment Harm 180-day mortality case-control study 139,103 180-day mortality HR 1.41 (95% CI 1.38-1.44) for benzodiazepines; HR 1.16 (95% CI 1.12-1.20) for antipsychotics JAMA Network Open 2025
✓ Peer-reviewed PMID 41085983

How this table was built, and where it is weak →