Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Every row

Showing 1 of 382 rows. One row per study per exposure: a study that tested two different things appears twice, once for each.

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Research and outcomes, 1 row. Every row links to its source.
Exposure Question Direction Outcome measured Design People Effect size, as the source reported it Source
Cannabinoid (THC/CBD) for agitation in severe dementia Medicines Treatment No effect
why

No difference from placebo on the primary agitation outcome or other main behavioural outcomes. As-needed psychotropic use was lower during the active period, and no serious drug-related adverse events occurred.

Agitation on the Cohen-Mansfield Agitation Inventory (primary); as-needed psychotropic use; safety randomised trial 25 not established — pubmed abstract results: "no significant difference was observed between active treatment and placebo for the cmai and other main behavioural… Age and ageing 2026
✓ Peer-reviewed PMID 42613673

How this table was built, and where it is weak →