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Home › Research › What the research found › Every row

Every row of the evidence table

One row per finding: what was tested, which way the result went, and how the study was built. The answer by area, and where the studies disagree, are on the main page.

Every row

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Area All 382 Care, carers and services 140 Medicines 85 Genes (not modifiable) 35 All modifiable factors together 27 Diet and supplements 23 Exercise and activity 21 Sleep, mood and social life 19 Hearing and vision 8 Alcohol, tobacco and cannabis 6 Infection and vaccination 5 Heart and metabolic health 4 Injury, delirium and falls 4 Environment 3 Cognitive activity 2
Question Both Prevention 190 Treatment 192
Direction Any Benefit 144 Harm 105 No effect 38 Mixed 37 No direction reported 58
Design Any meta-analysis 57 randomised trial 44 phase 3 trial 15 systematic review 9 phase 2 trial 10 cohort study 136 phase 1 trial 2 cross-sectional study 31 case-control study 14 modelling study 20 regulatory decision 7 company announcement 1 coverage determination 1 None 35
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Showing 1 of 382 rows for MRI amygdalar atrophy scale (marker of LATE). One row per study per exposure: a study that tested two different things appears twice, once for each.

Scroll the table sideways to see every column.

Research and outcomes, 1 row. Every row links to its source.
Exposure Question Direction Outcome measured Design People Effect size, as the source reported it Source
MRI amygdalar atrophy scale (marker of LATE) Care, carers and services Treatment No direction reported
why

A classification-validation study without a neuropathological reference standard, so accuracy cannot be judged. The groups behaved as expected: patients labelled LATE had mild amnestic impairment, limbic atrophy and stable MMSE over 30 months, while AD and AD/LATE groups declined.

 Clinical, imaging and 30-month cognitive profiles of memory-clinic patients classified as LATE, AD, AD/LATE or neither by the amygdalar atrophy scale plus AD biomarkers cohort study 469 the LATE group maintained cognitive stability as the No-AD/No-LATE group (β = -0.010, 95% CI -0.096 to 0.075, p = 0.813), whereas both AD (β = -0.136, 95% CI -0.184 to -0.088, p < 0.001) and AD/LATE (β = -0.139, 95% CI -0.196 to -0.082, p < 0.001) groups showed faster decline over time Neurology 2026
✓ Peer-reviewed PMID 41428981

How this table was built, and where it is weak →