Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Every row

Showing 1 of 382 rows. One row per study per exposure: a study that tested two different things appears twice, once for each.

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Research and outcomes, 1 row. Every row links to its source.
Exposure Question Direction Outcome measured Design People Effect size, as the source reported it Source
Physical activity (general / dose) Exercise and activity Prevention No effect
why

No difference between aerobic training and stretching/balance. Cognition was stable in both arms, but with no non-exercising control the trial cannot say whether either arm helped.

ADAS-Cog-Exec 12-month cognitive trajectory phase 3 trial 296 Between-group cognitive difference -0.078 (SE 0.074, p=0.3); 12-month hippocampal volume loss 0.51% in both arms Alzheimer's & Dementia 2025
✓ Peer-reviewed PMID 40271888

How this table was built, and where it is weak →