% alzhub.org topic: tdp-43
% Source: https://alzhub.org/topic/tdp-43
% 1157 entries, in the order the page lists them. Built from alzhub.org's own records.
% 1 entries have no readable author in the source record and carry no author field.

@article{worrall2026-1bda82c8,
  author  = {Worrall, Bradford B. and Ratan, Rajiv R.},
  title   = {{What Do Sugar, Gila Monsters, and the Therapeutic Dance Have in Common With GLP-1RA, Stroke, and Dementia?}},
  journal = {Neurology Genetics},
  year    = {2026},
  doi     = {10.1212/nxg.0000000000200450},
  url     = {https://doi.org/10.1212/nxg.0000000000200450}
}

@article{tan2026-e830449b,
  author  = {Tan, S. Y. and Naessens, M. and Jones, P. S. and Todd, E. G. and Williams, R. S. and Rodgers, C. T. and Hughes, L. E. and Shapiro and others},
  title   = {{Myo-inositol as a spectroscopic marker of neuroinflammation in frontotemporal lobar degeneration}},
  journal = {medRxiv (preprint)},
  year    = {2026},
  doi     = {10.64898/2026.09.18.26363386},
  url     = {https://doi.org/10.64898/2026.09.18.26363386}
}

@article{rash2026-3d07c8bf,
  author  = {Rash, B. G. and Levitina, S. and Botbyl, J. and Conklin, C. and Ingalhalikar, M. and Hare, J. M.},
  title   = {{Laromestrocel preserves brain volume and cognitive function in Alzheimers disease by inhibiting neuroinflammation}},
  journal = {medRxiv (preprint)},
  year    = {2026},
  doi     = {10.64898/2026.09.16.26363132},
  url     = {https://doi.org/10.64898/2026.09.16.26363132}
}

@article{petralla2026-e6cc30a0,
  author  = {Petralla, Sabrina and Hyvärinen, Jooseppi and Gynther, Mikko and Afonin, Alexey and Lehtonen, Marko and Auriola, Seppo and Panayotova, Maria and Kanninen, Katja M. and others},
  title   = {{Altered Membrane Protein Abundance in the Cerebral Cortex of the JNPL3 Mouse Model of Tauopathy}},
  journal = {Journal of Proteome Research},
  year    = {2026},
  doi     = {10.1021/acs.jproteome.6c00679},
  url     = {https://doi.org/10.1021/acs.jproteome.6c00679}
}

@article{abdelrasol2026-42742907,
  author  = {Abdel-Rasol, Mohammed A.},
  title   = {{Pharmacological modulation of cGAS-STING-NLRP3 signaling by nano-immunomodulators in Alzheimer and Parkinson disease}},
  journal = {Inflammopharmacology},
  year    = {2026},
  doi     = {10.1007/s10787-026-02386-0},
  pmid    = {42742907},
  url     = {https://doi.org/10.1007/s10787-026-02386-0}
}

@article{yang2026-a81a35f6,
  author  = {Yang, D. and Bartolomeo, K. R. and Liu, S. and Gonzalez-Vicente, A. and Wheeler, N. R. and Benchek, P. and Zhu, X. and Haines and others},
  title   = {{The APOL1 protective M1 modifier occurs exclusively with the KIK protein haplotype to suppress channel conductance}},
  journal = {medRxiv (preprint)},
  year    = {2026},
  doi     = {10.64898/2026.09.14.26362999},
  url     = {https://doi.org/10.64898/2026.09.14.26362999}
}

@article{narasimhappagari2026-e38b6498,
  author  = {Narasimhappagari, Jagadeesh and Liu, Ling and Ayyadevara, Srinivas and Griffin, W. Sue T.},
  title   = {{Ibuprofen modulates inflammatory and autophagy-associated pathways linked to neurodegenerative pathology in APOE-context-dependent cellular models}},
  journal = {Journal of Neuroinflammation},
  year    = {2026},
  doi     = {10.1186/s12974-026-04038-0},
  url     = {https://doi.org/10.1186/s12974-026-04038-0}
}

@article{li2026-42769145,
  author  = {Li, Jun and Liu, Guanglin and Wang, Xiaotong and Song, Zheng and Chen, Huan and Hou, Hongwei and Hu, Qingyuan},
  title   = {{Adult-onset hippocampal α7 nicotinic acetylcholine receptor loss rapidly drives Alzheimer-like neuropathology in mice}},
  journal = {Frontiers in Pharmacology},
  year    = {2026},
  doi     = {10.3389/fphar.2026.1929468},
  pmid    = {42769145},
  url     = {https://doi.org/10.3389/fphar.2026.1929468}
}

@article{cao2026-517396ca,
  author  = {Cao, X. and Sun, H. and Feng, R. and Mazumder, R. and Najar, C. F. B. A. and Li, Y. I. and De Jager, P. L. and Bennett and others},
  title   = {{Integrative multi-omics QTL colocalization maps regulatory architecture in aging human brain}},
  journal = {medRxiv (preprint)},
  year    = {2026},
  doi     = {10.1101/2025.04.17.25326042},
  url     = {https://doi.org/10.1101/2025.04.17.25326042}
}

@article{silva2026-42616837,
  author  = {Silva, M. Catarina and Lindmeier, Hannah and Pigini, Paolo and Laughlin, J.S. and Yu, Yong and Morrill, Christie and Arnold, Michael A. and Barraza, Scott J. and others},
  title   = {{MAPT splicing modulators reduce 4R tau and rescue tauopathy phenotypes in human neurons and in a mouse model}},
  journal = {Science Translational Medicine},
  year    = {2026},
  doi     = {10.1126/scitranslmed.ady6759},
  pmid    = {42616837},
  url     = {https://doi.org/10.1126/scitranslmed.ady6759}
}

@article{bouchelit2026-371ff4d0,
  author  = {Bouchelit, Mohammed El Amin},
  title   = {{Stress-Specific Mitochondrial Reserve as a Candidate Modifier of Lipid-Driven Synaptic Failure in Alzheimer Disease}},
  journal = {Zenodo (CERN European Organization for Nuclear Research)},
  year    = {2026},
  doi     = {10.5281/zenodo.21854145},
  url     = {https://doi.org/10.5281/zenodo.21854145}
}

@article{bouchelit2026-8f7376fd,
  author  = {Bouchelit, Mohammed El Amin},
  title   = {{Stress-Specific Mitochondrial Reserve as a Candidate Modifier of Lipid-Driven Synaptic Failure in Alzheimer Disease}},
  journal = {Zenodo (CERN European Organization for Nuclear Research)},
  year    = {2026},
  doi     = {10.5281/zenodo.21854146},
  url     = {https://doi.org/10.5281/zenodo.21854146}
}

@article{gunasekaran2026-cddcbabb,
  author  = {Gunasekaran, T. I. and Reyes-Dumeyer, D. and Gu, Y. and Volpert, O. and Beauregard, D. and Albers, L. and Teich, A. and Honig, L. S. and others},
  title   = {{Antemortem α-Synuclein levels from neuron-derived extracellular vesicles identify Lewy Body pathology in Parkinson’s Disease and Alzheimer Disease}},
  journal = {medRxiv},
  year    = {2026},
  doi     = {10.64898/2026.08.03.26359636},
  url     = {https://doi.org/10.64898/2026.08.03.26359636}
}

@article{zheng2026-42562773,
  author  = {Zheng, Xiaojing and Zhang, Ning and Wang, Lixia and Zhao, Hongjuan and Liu, ChengGang and Wang, Jiayu and Zhao, Wanli and Zhao, Junli and others},
  title   = {{A phosphorylation‑independent monoclonal antibody improves detection of TDP‑43 pathology across frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and limbic predominant age related TDP‑43 encephalopathy neuropathological change}},
  journal = {Journal of Neuropathology \& Experimental Neurology},
  year    = {2026},
  doi     = {10.1093/jnen/nlag085},
  pmid    = {42562773},
  url     = {https://doi.org/10.1093/jnen/nlag085}
}

@article{sun2026-42411568,
  author  = {Sun, Xiaohuan and Ramakrishnan, Skandha and Ogbolu, Victor C. and Kanaan, Nicholas M. and Karch, Celeste M M. and Baas, Peter W. and Liang, Qiang},
  title   = {{Patient‐derived forebrain cortical organoids reveal biphasic tau–MAP6–microtubule axis dysfunction in tauopathy}},
  journal = {Alzheimer s \& Dementia},
  year    = {2026},
  doi     = {10.1002/alz.71565},
  pmid    = {42411568},
  url     = {https://doi.org/10.1002/alz.71565}
}

@article{tu2026-42434904,
  author  = {Tu, Huan and Sun, Rongzhen and Ma, Shengyao and Li, Chunxu and Lv, Mingti and Han, M H and Zhang, Han‐Ting},
  title   = {{PDE4A knockdown rescues alcohol-induced cognitive impairment and synaptic dysfunction via the cAMP/PKA/CREB pathway}},
  journal = {The International Journal of Neuropsychopharmacology},
  year    = {2026},
  doi     = {10.1093/ijnp/pyag031},
  pmid    = {42434904},
  url     = {https://doi.org/10.1093/ijnp/pyag031}
}

@article{cook2026-42264399,
  author  = {Cook, Anna K. and Lin, Benjamin and Song, Yumo and Greathouse, Kelsey M. and Kaplelach, Azariah K. and Love, Mackenzie L. and Davis, Skylar E. and Stoll, Anna C. and others},
  title   = {{Human TDP-43 expression worsens FTD-related phenotypes in progranulin-insufficient mice}},
  journal = {Neurobiology of Disease},
  year    = {2026},
  doi     = {10.1016/j.nbd.2026.107475},
  pmid    = {42264399},
  url     = {https://doi.org/10.1016/j.nbd.2026.107475}
}

@article{ball2026-42248860,
  author  = {Ball, Hannah E. and Woods, Abby C. and Wong, Yvette C.},
  title   = {{TDP-43 oxidation and PP1 crosstalk at RNA granule-mitochondria contact sites}},
  journal = {Nature Communications},
  year    = {2026},
  doi     = {10.1038/s41467-026-74009-9},
  pmid    = {42248860},
  url     = {https://doi.org/10.1038/s41467-026-74009-9}
}

@article{guo2026-40949955,
  author  = {Guo, Caiwei and Chen, Kuchuan and Vatsavayai, Sarat C. and Akiyama, Tetsuya and Liu, Chang and Zeng, Yi Bo and Sianto, Odilia and Yang, Edith and others},
  title   = {{Cryptic splicing in synaptic and membrane excitability genes links TDP-43 loss to neuronal dysfunction}},
  journal = {Science Translational Medicine},
  year    = {2026},
  doi     = {10.1126/scitranslmed.aeb8517},
  pmid    = {40949955},
  url     = {https://doi.org/10.1126/scitranslmed.aeb8517}
}

@article{villanueva2026-42226039,
  author  = {Villanueva, Erika B. and Zebec, Zala and Cisquella-Serra, Marina and Lundstrøm, Jon and Andersen, JB and Qvist, Filippa Liliendahl and Westi, Emil Winther and Marín, Andrea and others},
  title   = {{Distinct and combined interferon-ɑ/β-receptor-1 loss in neurons and astrocytes disrupt brain energy metabolism and drive Parkinsonian dementia}},
  journal = {Journal of Biomedical Science},
  year    = {2026},
  doi     = {10.1186/s12929-026-01257-8},
  pmid    = {42226039},
  url     = {https://doi.org/10.1186/s12929-026-01257-8}
}

@article{huang2026-42271186,
  author  = {Huang, Chunmei and Cai, Qin and Feng, Zeru and Chenze, Zhang and Luo, Zhiqiang and Cheng, Xingqun and Wu, H},
  title   = {{Porphyromonas gingivalis disrupts hippocampal circadian clock via PI3K/AKT pathway, exacerbating Alzheimer‐like pathology}},
  journal = {Alzheimer s \& Dementia},
  year    = {2026},
  doi     = {10.1002/alz.71543},
  pmid    = {42271186},
  url     = {https://doi.org/10.1002/alz.71543}
}

@article{malenchini2026-42278362,
  author  = {Malenchini, Marta and Beretti, Francesca and Gatti, Martina and Bertucci, Emma and Del Toro, Elena and Maraldi, Tullia},
  title   = {{Stem Cell-Derived Extracellular Vesicles Ameliorate the Neuron Mitochondrial Damage Induced by ROS-, LPS-Exposure: In Vitro Model of Neuron, Microglia, and Astrocyte Triple Co-Culture}},
  journal = {International Journal of Molecular Sciences},
  year    = {2026},
  doi     = {10.3390/ijms27114834},
  pmid    = {42278362},
  url     = {https://doi.org/10.3390/ijms27114834}
}

@article{nikodemova2026-1be8ffe0,
  author  = {Nikodémová, Mária and Byrne, Barry and Fuller, David},
  title   = {{Spinal microglia are dysregulated in a rat model of Pompe disease}},
  journal = {Physiology},
  year    = {2026},
  doi     = {10.1152/physiol.2026.41.s1.2299248},
  url     = {https://doi.org/10.1152/physiol.2026.41.s1.2299248}
}

@article{wang2026-42187024,
  author  = {Wang, Dongsheng and Ta, Vinh and Wang, Hongxia and Ju, Jerica and Wang, Chun and Chehadeh, Christine and Torreblanca-Zanca, Albertina and Magaña, Yessenia and others},
  title   = {{Systemic delivery of synapsin‐promoted caveolin‐1 overexpression ameliorates pathological TDP‐43–induced cognitive decline and neurodegenerative changes}},
  journal = {Alzheimer s \& Dementia},
  year    = {2026},
  doi     = {10.1002/alz.71450},
  pmid    = {42187024},
  url     = {https://doi.org/10.1002/alz.71450}
}

@article{kumar2026-781836ef,
  author  = {Kumar, Rika and Shinn, Grace and Lin, Jimmy and Li, Qingshun Quinn and Hong, Yiling},
  title   = {{Advanced Glycation End Products Induce Microglial Activation and Impair Neurodevelopment in Human iPSC-Derived Brain Organoids}},
  journal = {Organoids},
  year    = {2026},
  doi     = {10.3390/organoids5020012},
  url     = {https://doi.org/10.3390/organoids5020012}
}

@article{jiang2026-41984931,
  author  = {Jiang, Yixiang and Tetlow, Amber M. and Lin, Yan and Ji, Changyi and Ader, Jack and Laborc, Klaudia Flóra and Mar, Adam C. and Pan, Ruimin and others},
  title   = {{Autophagosome-targeting single-domain antibody clears tau in patient-derived neurons and improves motor function in tauopathy mice}},
  journal = {Science Translational Medicine},
  year    = {2026},
  doi     = {10.1126/scitranslmed.aea4205},
  pmid    = {41984931},
  url     = {https://doi.org/10.1126/scitranslmed.aea4205}
}

@article{dicaro2026-41943055,
  author  = {Di Caro, V. and Cho, E. and Thiel, J. and Lizama, B. N. and Koel-Simmelink, M. J. A. and Pandey, K. and Duong, D. and Seyfried, N. T. and others},
  title   = {{Impact of zervimesine on the neuroinflammatory biomarker GFAP and related proteomic molecular correlates in plasma of participants from a phase 2 clinical trial in Alzheimer's disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2026},
  doi     = {10.1186/s13195-026-02025-4},
  pmid    = {41943055},
  url     = {https://doi.org/10.1186/s13195-026-02025-4}
}

@article{shou2026-41935066,
  author  = {Shou, Rongshang and Wang, Ziyue and Han, Zige and Li, Anyao and Shang, Jiaxin and Lou, HaiYue and Zhang, Xiaotong and Zhan, Yingqi and others},
  title   = {{Dietary silver nanoparticle supplementation induces Alzheimer-like lesions through Bifidobacterium deficiency-dominated gut microbiota dysbiosis and neuroinflammation}},
  journal = {npj Science of Food},
  year    = {2026},
  doi     = {10.1038/s41538-026-00820-9},
  pmid    = {41935066},
  url     = {https://doi.org/10.1038/s41538-026-00820-9}
}

@article{timko2026-41931297,
  author  = {Timko, Noah J. and Wright, Mary Cooter and Reese, Melody A. and Boykin, Piper C. and Emerson, Jacqueline M. and Woldorff, Marty G. and Eleswarpu, Sarada and Herbert, J. Taylor and others},
  title   = {{Apolipoprotein E Mimetic Peptide CN-105 and Postoperative Delirium in Older Patients}},
  journal = {JAMA Network Open},
  year    = {2026},
  doi     = {10.1001/jamanetworkopen.2026.2289},
  pmid    = {41931297},
  url     = {https://doi.org/10.1001/jamanetworkopen.2026.2289}
}

@article{viola2026-41925203,
  author  = {Viola, Giovanna and Sperotto, Andrea and Palmioli, Alessandro and Tira, Roberto and Munari, Francesca and Assfalg, Michael and Airoldi, Cristina and D’Onofrio, Mariapina},
  title   = {{Cinnamon Bud Extract Is a Source of Biomolecules Active against the Aggregation and Condensation of Alzheimer′s-Associated Tau Protein}},
  journal = {Journal of Agricultural and Food Chemistry},
  year    = {2026},
  doi     = {10.1021/acs.jafc.5c17659},
  pmid    = {41925203},
  url     = {https://doi.org/10.1021/acs.jafc.5c17659}
}

@article{mendez2026-41920173,
  author  = {Mendez, Joel Sanchez and Queme, Bryan and Fu, Yubo and Morrison, John L. and Lewinger, Juan Pablo and Kawaguchi, Eric S. and Mi, Huaiyu and Obón‐Santacana, Mireia and others},
  title   = {{TGF-β Pathway–Based Polygenic Risk Score Modifies the Association between Red Meat Intake and Colorectal Cancer Risk: Application of a Novel Pathway-Based PRS Method}},
  journal = {Cancer Epidemiology Biomarkers \& Prevention},
  year    = {2026},
  doi     = {10.1158/1055-9965.epi-25-1754},
  pmid    = {41920173},
  url     = {https://doi.org/10.1158/1055-9965.epi-25-1754}
}

@article{jia2026-22fe2677,
  author  = {Jia, Yanli and Ren, Yanyan and Yu, Yunmei and Dong, Fangming and Geng, Minxia and Feng, Rongfang},
  title   = {{SHP2 in microglia attenuates neuroinflammation and cognitive deficits in vascular dementia by modulating the FAK/Src/PU. 1/IRF8 pathway}},
  journal = {European journal of medical research},
  year    = {2026},
  doi     = {10.1186/s40001-026-04317-9},
  url     = {https://doi.org/10.1186/s40001-026-04317-9}
}

@article{mamede2026-41875078,
  author  = {Mamede, Lohany Dias and Hu, Miwei and Vaquer-Alicea, Jaime III and Titus, Amanda R. and dos Passos, Patricia M. and Lantelme, Erica and French, Rachel L. and Kirschner, Paige A. and others},
  title   = {{A quantitative cell-based reporter links TDP-43 aggregation and dysfunction to define pathogenic mechanisms}},
  journal = {PLoS Biology},
  year    = {2026},
  doi     = {10.1371/journal.pbio.3003662},
  pmid    = {41875078},
  url     = {https://doi.org/10.1371/journal.pbio.3003662}
}

@article{ritsachel2026-31d8a212,
  author  = {Ritsachel, Glen Charles and Claude},
  title   = {{Single-Cell Transcriptomic Identification of SYK Kinase as a Therapeutic Target in Disease-Associated Microglia for Alzheimer's Disease Treatment}},
  journal = {Zenodo (CERN European Organization for Nuclear Research)},
  year    = {2026},
  doi     = {10.5281/zenodo.19194338},
  url     = {https://doi.org/10.5281/zenodo.19194338}
}

@article{ritsachel2026-eb49b3ac,
  author  = {Ritsachel, Glen Charles and Claude},
  title   = {{Single-Cell Transcriptomic Identification of SYK Kinase as a Therapeutic Target in Disease-Associated Microglia for Alzheimer's Disease Treatment}},
  journal = {Zenodo (CERN European Organization for Nuclear Research)},
  year    = {2026},
  doi     = {10.5281/zenodo.19194339},
  url     = {https://doi.org/10.5281/zenodo.19194339}
}

@article{perry2026-41813136,
  author  = {Perry, Cailyn M. and Martin, Dale D. O.},
  title   = {{ALS and Huntington Disease: Unraveling the Connections between TDP-43 and Huntingtin}},
  journal = {Journal of Neuroscience},
  year    = {2026},
  doi     = {10.1523/jneurosci.0263-25.2026},
  pmid    = {41813136},
  url     = {https://doi.org/10.1523/jneurosci.0263-25.2026}
}

@article{jamerlan2026-41900026,
  author  = {Jamerlan, Angelo and Hulme, John},
  title   = {{Chemical and Molecular Strategies in Restoring Autophagic Flux in TDP-43 Proteinopathy}},
  journal = {Molecules},
  year    = {2026},
  doi     = {10.3390/molecules31060924},
  pmid    = {41900026},
  url     = {https://doi.org/10.3390/molecules31060924}
}

@article{chakraborty2026-41807755,
  author  = {Chakraborty, Anirban and Mitra, Joy and Malojirao, Vikas H. and Kodavati, Manohar M. and Mandal, Santi M. and Gill, Satkarjeet K. and Sreenivasmurthy, Sravan Gopalkrishnashetty and Vasquez, Velmarini and others},
  title   = {{Fructose-2,6-bisphosphate restores TDP-43 pathology-driven genome repair deficiency in motor neuron diseases}},
  journal = {Communications Biology},
  year    = {2026},
  doi     = {10.1038/s42003-026-09787-5},
  pmid    = {41807755},
  url     = {https://doi.org/10.1038/s42003-026-09787-5}
}

@article{guo2026-41807703,
  author  = {Guo, Shenrui and Jin, Hongfu and Sun, Hui and Huang, Shuo and Chen, Yuanyuan and Chang, Yuge and Zhang, Yu and Ding, Lin and others},
  title   = {{TDP-43 pathology triggers neuroinflammation and cognitive impairment by inducing microglial necroptosis}},
  journal = {EMBO Molecular Medicine},
  year    = {2026},
  doi     = {10.1038/s44321-026-00394-9},
  pmid    = {41807703},
  url     = {https://doi.org/10.1038/s44321-026-00394-9}
}

@article{jagaraj2026-41804798,
  author  = {Jagaraj, Cyril Jones and Saravanabavan, Sayanthooran and Parakh, Sonam and Jayakumar, Mrithulabashini and Kashani, Sara Assar and Shadfar, Sina and Mehta, Prachi M. and Gautam, Shashi and others},
  title   = {{Cofilin hyperphosphorylation triggers TDP-43 pathology in sporadic amyotrophic lateral sclerosis}},
  journal = {Brain},
  year    = {2026},
  doi     = {10.1093/brain/awag096},
  pmid    = {41804798},
  url     = {https://doi.org/10.1093/brain/awag096}
}

@article{ye2026-41943580,
  author  = {Ye, Yingzhi and Zhang, Zhe and Xiao, Yu and Zhu, Chengzhang and Wright, Noelle and Asbury, Julie and Huang, Yongxin and Wang, Wei J. and others},
  title   = {{DCPS modulates TDP-43-linked neurodegeneration through P-body-mediated RNA decay}},
  journal = {Neuron},
  year    = {2026},
  doi     = {10.1016/j.neuron.2026.01.018},
  pmid    = {41943580},
  url     = {https://doi.org/10.1016/j.neuron.2026.01.018}
}

@article{rodriguez2026-0f626c1d,
  author  = {Rodriguez, Quentin and Payet, Floriane and Vargas-Baron, Karina and Borel, Eve and Lanté, Fabien and Boisseau, Sylvie and Blot, Béatrice and Girault, Jean‐Antoine and others},
  title   = {{Pyk2 plays a critical role in synaptic dysfunction during the early stages of Alzheimer’s disease}},
  journal = {Molecular Neurodegeneration Advances},
  year    = {2026},
  doi     = {10.1186/s44477-026-00021-4},
  url     = {https://doi.org/10.1186/s44477-026-00021-4}
}

@article{zhao2026-41796799,
  author  = {Zhao, Dorothy Yanling and Nabeel‐Shah, Syed and Ni, Zuyao and Pu, Shuye and Zhong, Guoqing and Schmitges, Frank W. and Braunschweig, Ulrich and Blencowe, Benjamin J. and others},
  title   = {{RNA-binding proteins TDP-43 and FUS promote R-loop resolution and regulate transcription termination}},
  journal = {Journal of Biological Chemistry},
  year    = {2026},
  doi     = {10.1016/j.jbc.2026.111348},
  pmid    = {41796799},
  url     = {https://doi.org/10.1016/j.jbc.2026.111348}
}

@article{chen2026-41785364,
  author  = {Chen, Yun and Liu, Yizhou A. and Nguyen, Khai M. and Wu, Junjie and Song, Sihui and Lin, Kent and Rodrigues, Patrick Fernandes and Du, Siling and others},
  title   = {{Targeting amyloid-β pathology by chimeric antigen receptor astrocyte (CAR-A) therapy}},
  journal = {Science},
  year    = {2026},
  doi     = {10.1126/science.ads3972},
  pmid    = {41785364},
  url     = {https://doi.org/10.1126/science.ads3972}
}

@article{brossaud2026-41786890,
  author  = {Brossaud, Rodrigue and Oullier, Thibauld and Bessard, Anne Claire Hardy and Aubert, P. and Brossard, Lisa and Mahé, Maxime M. and Caillaud, Martial and Delfino, Giada and others},
  title   = {{The short-chain fatty acid butyrate prevents gut-brain amyloid-β pathology and neuroinflammation in an Alzheimer mouse model}},
  journal = {Molecular Psychiatry},
  year    = {2026},
  doi     = {10.1038/s41380-026-03522-6},
  pmid    = {41786890},
  url     = {https://doi.org/10.1038/s41380-026-03522-6}
}

@article{wang2026-41688738,
  author  = {Wang, Shuai and Ponnusamy, Moorthi and Patel, Om and Hansen, Mitchell T. and Collier, Lisa A. and Collier, Shane and Thinakaran, Gopal},
  title   = {{Spatiotemporal transcriptomic profiling reveals upregulation of glycolysis pathway genes before overt tauopathy in the PS19 mouse model}},
  journal = {Experimental \& Molecular Medicine},
  year    = {2026},
  doi     = {10.1038/s12276-026-01652-z},
  pmid    = {41688738},
  url     = {https://doi.org/10.1038/s12276-026-01652-z}
}

@article{puech2026-41630648,
  author  = {Puech, Clémentine and Sadanand, Anjana and Coleman, Neil M. and Ikhane, Marilyn and Badran, Mohammad and Wang, Rong and Gozal, David and Parent, A.},
  title   = {{APP‐mediated intracellular signaling rescues sleep impairment and blood–brain barrier leakage in Alzheimer's disease mouse model}},
  journal = {Alzheimer s \& Dementia},
  year    = {2026},
  doi     = {10.1002/alz.71134},
  pmid    = {41630648},
  url     = {https://doi.org/10.1002/alz.71134}
}

@article{chen2026-41670794,
  author  = {Chen, Xiangting and Huang, Yueqing and Zhao, Chunhua and Huang, Min},
  title   = {{Association between leukocyte telomere length and neurodegenerative diseases: a prospective cohort in the UK Biobank}},
  journal = {Journal of Neurology},
  year    = {2026},
  doi     = {10.1007/s00415-025-13479-1},
  pmid    = {41670794},
  url     = {https://doi.org/10.1007/s00415-025-13479-1}
}

@article{johnson2026-41617706,
  author  = {Johnson, L. A. and Saito, K. and Pallerla, A. V. and Funnell, J. L. and Ezzo, A. R. and Song, C. M. and Harrison, D. A. and Norton, N. J. and Moore, L. C. and Van Eldik, L. J. and others},
  title   = {{Clonal expansion of cytotoxic CD8⁺ T cells in lecanemab-associated ARIA}},
  journal = {Nature Communications},
  year    = {2026},
  doi     = {10.1038/s41467-026-68921-3},
  pmid    = {41617706},
  url     = {https://doi.org/10.1038/s41467-026-68921-3}
}

@article{purvinsh2026-41609580,
  author  = {Purvinsh, Yana and Matveyenka, Mikhail and Kurouski, Dmitry},
  title   = {{Elucidation of Molecular Mechanisms of Lipid-Altered Cytotoxicity of TDP-43 Fibrils}},
  journal = {ACS Chemical Neuroscience},
  year    = {2026},
  doi     = {10.1021/acschemneuro.5c00934},
  pmid    = {41609580},
  url     = {https://doi.org/10.1021/acschemneuro.5c00934}
}

@article{qi2026-41604700,
  author  = {Qi, Zihe and Li, Qianyu and Cao, Juanjuan and Xu, Bufan and Jiang, Fan and Wang, Yanbo and Wu, Di and Li, Guoliang},
  title   = {{Chronic Exposure to Thermally Processed Food-Derived Carbon Polymers Accelerated Neuroinflammation in Alzheimer Disease Mice through Microbe–Gut–Brain Axis}},
  journal = {Journal of Agricultural and Food Chemistry},
  year    = {2026},
  doi     = {10.1021/acs.jafc.5c11423},
  pmid    = {41604700},
  url     = {https://doi.org/10.1021/acs.jafc.5c11423}
}

@article{weng2026-41676156,
  author  = {Weng, Ying and He, Ting and Li, Mengzhu and Zhou, Qiuzhi and Xie, Jiazhao and Wei, Linyu and Wang, Xin and Wang, Jian-Zhi and others},
  title   = {{Microglial histone H3K18 crotonylation promotes STAT1 expression and induces cognitive deficit in Alzheimer disease}},
  journal = {Frontiers in Immunology},
  year    = {2026},
  doi     = {10.3389/fimmu.2026.1744375},
  pmid    = {41676156},
  url     = {https://doi.org/10.3389/fimmu.2026.1744375}
}

@article{cruz2026-7762a1d1,
  author  = {Cruz, L. A. and Liu, S. and Miskimen, K. L. and Cooke Bailey, J. N. and Kinzy, T. and Song, Y. E. and Laux, R. A. and Miron, P. and others},
  title   = {{Evidence for reduced somatic T-cell receptor sequence diversity profiles among Midwestern Amish in an aging cohort study}},
  journal = {Annals of human genetics},
  year    = {2026},
  doi     = {10.64898/2026.01.25.26344754},
  url     = {https://doi.org/10.64898/2026.01.25.26344754}
}

@article{jamerlan2026-41683564,
  author  = {Jamerlan, Angelo and Hulme, John},
  title   = {{From Evasion to Collapse: The Kinetic Cascade of TDP-43 and the Failure of Proteostasis}},
  journal = {International Journal of Molecular Sciences},
  year    = {2026},
  doi     = {10.3390/ijms27031136},
  pmid    = {41683564},
  url     = {https://doi.org/10.3390/ijms27031136}
}

@article{li2026-41576952,
  author  = {Li, X. and Tang, X. and Zeng, J. and Duan, L. and Hou, Z. and Li, L. and Guo, Y. and Chai, C. and Liu, J. and Wang, Y. and Zhu, L. Q. and Li, H. and others},
  title   = {{Peripheral cancer attenuates amyloid pathology in Alzheimer's disease via cystatin-c activation of TREM2}},
  journal = {Cell},
  year    = {2026},
  doi     = {10.1016/j.cell.2025.12.020},
  pmid    = {41576952},
  url     = {https://doi.org/10.1016/j.cell.2025.12.020}
}

@article{song2026-41540503,
  author  = {Song, Chengcheng and Wu, Pau Yen and Huffman, William J. and David‐Bercholz, Jennifer and Bedolla, Alicia and Velagapudi, Ravikanth and Njoroge, Ann Wangechi and Rodriguiz, Ramona M. and others},
  title   = {{Electrical stimulation of the vagus nerve improves amyloid pathology in delirium superimposed on dementia}},
  journal = {Bioelectronic Medicine},
  year    = {2026},
  doi     = {10.1186/s42234-025-00194-5},
  pmid    = {41540503},
  url     = {https://doi.org/10.1186/s42234-025-00194-5}
}

@article{mir2026-41524247,
  author  = {Mir, Hayatte-Dounia and Giorgini, Giada and Santos‐García, Irene and Dumais, Elizabeth and Rodríguez‐Cueto, Carmen and de Lago, Eva and Silvestri, Cristoforo and Flamand, Nicolas and others},
  title   = {{Defining the Intestinal eCBome and Oxylipin Signaling Systems in a TDP‐43 Mouse Model of Frontotemporal Dementia}},
  journal = {The FASEB Journal},
  year    = {2026},
  doi     = {10.1096/fj.202502312rr},
  pmid    = {41524247},
  url     = {https://doi.org/10.1096/fj.202502312rr}
}

@article{draper2026-41525887,
  author  = {Draper, Derk and George, Anna E. and Veenendaal, Tineke and van Dijk, Suzanne M. and Soltani, Elly and Sanzà, Paolo and Verweij, Frederik J. and Klumperman, Judith and others},
  title   = {{HOPS disruption impairs APP trafficking and processing, promoting exosomal secretion of APP-CTFs}},
  journal = {Neurobiology of Disease},
  year    = {2026},
  doi     = {10.1016/j.nbd.2026.107269},
  pmid    = {41525887},
  url     = {https://doi.org/10.1016/j.nbd.2026.107269}
}

@article{ciervo2026-41499526,
  author  = {Ciervo, Yuri and Rigoni, Pietro and Bucciarelli, Linda and Lombi, Martina and Pratesi, Federico and Bologna, Nadia and Accardo, Massimo and Recchi, Chiara and others},
  title   = {{Restoration of progranulin by engineered hematopoietic stem cell–derived microglia corrects phenotypes of granulin knockout mice}},
  journal = {Science Translational Medicine},
  year    = {2026},
  doi     = {10.1126/scitranslmed.adw9930},
  pmid    = {41499526},
  url     = {https://doi.org/10.1126/scitranslmed.adw9930}
}

@article{silvallanes2026-41486173,
  author  = {Silva-Llanes, Ignacio and Smith, Lilia A. and Abdelkader-Guillén, Aaron and Jiménez-Villegas, José and Sarrió, David and Gema, Moreno-Bueno and Lastres‐Becker, Isabel},
  title   = {{GASDERMIN D-mediated pyroptosis as a therapeutic target in TAU-dependent frontotemporal dementia mouse model}},
  journal = {Journal of Biomedical Science},
  year    = {2026},
  doi     = {10.1186/s12929-025-01210-1},
  pmid    = {41486173},
  url     = {https://doi.org/10.1186/s12929-025-01210-1}
}

@article{bharathi2026-41490046,
  author  = {Bharathi, Vidhya and Zeng, Yi and Armour, Ellen M. and Yue, Mei and Citrano, Kathryn and Lovchykova, Anastasiia and Reeves, Madison M. and Rawlinson, Bailey D. and others},
  title   = {{TDP-43-mediated alternative polyadenylation is associated with a reduction in VPS35 and VPS29 expression in frontotemporal dementia}},
  journal = {PLoS Biology},
  year    = {2026},
  doi     = {10.1371/journal.pbio.3003573},
  pmid    = {41490046},
  url     = {https://doi.org/10.1371/journal.pbio.3003573}
}

@article{tsai2026-41516384,
  author  = {Tsai, Hui‐Yun and Qiu, Jing Yi and Liao, Han-Wei and Chang, Chi‐I and Chen, Yu-Hsiang and Ho, Chi‐Tang and Chen, Yu-Kuo and others},
  title   = {{Propyl Gallate Attenuates Methylglyoxal-Induced Alzheimer-like Cognitive Deficits and Neuroinflammation in Mice}},
  journal = {International Journal of Molecular Sciences},
  year    = {2026},
  doi     = {10.3390/ijms27010511},
  pmid    = {41516384},
  url     = {https://doi.org/10.3390/ijms27010511}
}

@article{ibrahim2026-41484454,
  author  = {Ibrahim, Mennatallah and Khalil, Asmaa M. and Attia, Heba and Alseekh, Saleh and Mohamed, Ahmed F. and El-Yamany, Mohammed F.},
  title   = {{Gut Microbiome–Sphingolipid Metabolism–Brain Axis Interactions: Neuroprotective Effects of Amitriptyline as Functional Inhibitor of Acid Sphingomyelinase in a Mouse Model of Tauopathy}},
  journal = {Journal of Neuroimmune Pharmacology},
  year    = {2026},
  doi     = {10.1007/s11481-025-10270-x},
  pmid    = {41484454},
  url     = {https://doi.org/10.1007/s11481-025-10270-x}
}

@article{chai2026-41884592,
  author  = {Chai, Yuek Ling and Hilal, Saima and Cai, Vera Yuan and Mok, Vincent C. T. and Chong, Joyce Ruifen and Liao, Yingqi and Tan, Boon Yeow and Venketasubramanian, Narayanaswamy and others},
  title   = {{Elevated serum inflammasome adaptor protein ASC is associated with white matter hyperintensities in vascular cognitive impairment}},
  journal = {Brain Communications},
  year    = {2026},
  doi     = {10.1093/braincomms/fcag068},
  pmid    = {41884592},
  url     = {https://doi.org/10.1093/braincomms/fcag068}
}

@article{chen2026-42411051,
  author  = {Chen, H B and Guo, Y P and Huang, Weiyuan and Hu, Anquan and Liu, Tao and Chen, Feng},
  title   = {{Glymphatic dysfunction associates with regional white matter hyperintensities and plasma amyloid-β burden across the Alzheimer’s disease continuum}},
  journal = {Psychological Medicine},
  year    = {2026},
  doi     = {10.1017/s0033291726105005},
  pmid    = {42411051},
  url     = {https://doi.org/10.1017/s0033291726105005}
}

@article{white2026-41546756,
  author  = {White, Matthew A. and Crowley, Leon and Massenzio, Francesca and Li, Xingli and Niblock, Michael and Milani, Sara and Coleman, Michael P. and Barmada, Sami J. and others},
  title   = {{Inhibiting Glycogen Synthase Kinase 3 Suppresses TDP-43-Mediated Neurotoxicity in a Caspase-Dependent Manner}},
  journal = {Molecular Neurobiology},
  year    = {2026},
  doi     = {10.1007/s12035-026-05675-5},
  pmid    = {41546756},
  url     = {https://doi.org/10.1007/s12035-026-05675-5}
}

@article{arbaciauskaite2026-41678018,
  author  = {Arbaciauskaite, Skaiste and Silvestri, Simona and Luo, Pingyan and Krüger, Christina and Mossmann, Zoé J. and Allelein, Susann and Scholz, Alexander and Löffler, Dennis and others},
  title   = {{Microglia-Derived Extracellular Vesicles from Alzheimer’s Disease Patients Carry miRNAs Driving a Neuroinflammatory Response}},
  journal = {Molecular Neurobiology},
  year    = {2026},
  doi     = {10.1007/s12035-026-05719-w},
  pmid    = {41678018},
  url     = {https://doi.org/10.1007/s12035-026-05719-w}
}

@article{shenouda2026-41549027,
  author  = {Shenouda, Marc and Shenouda, Sandra and Kartono, Bryan and Eid, Shehab and Cheng, Cheryl and Robertson, Janice},
  title   = {{Small molecule JRMS modulating importin-β1 chaperone activity as a therapeutic strategy reducing TDP-43 pathology}},
  journal = {Neurotherapeutics},
  year    = {2026},
  doi     = {10.1016/j.neurot.2026.e00834},
  pmid    = {41549027},
  url     = {https://doi.org/10.1016/j.neurot.2026.e00834}
}

@article{korada2025-41460923,
  author  = {Korada, Shreevidya and Tam, Oliver H. and Greco, Hunter C. and Hammell, Molly and Dubnau, Josh and Sher, Roger B.},
  title   = {{LINE-1 retrotransposition in a mouse TDP-43 model of neurodegeneration marks motor cortex neurons for cell-intrinsic and cell non-autonomous programmed cell death}},
  journal = {PLoS Genetics},
  year    = {2025},
  doi     = {10.1371/journal.pgen.1012007},
  pmid    = {41460923},
  url     = {https://doi.org/10.1371/journal.pgen.1012007}
}

@article{maruyama2025-41418776,
  author  = {Maruyama, Riki and Fukumori, Akio and Funamoto, Satoru and Okada, Ken and Akamine, Shoshin and Yanagida, Kanta and Shinohara, Mitsuru and Sato, Naoyuki and others},
  title   = {{γ-Secretase exosites as targets for substrate-selective lowering of Aβ generation}},
  journal = {Structure},
  year    = {2025},
  doi     = {10.1016/j.str.2025.11.010},
  pmid    = {41418776},
  url     = {https://doi.org/10.1016/j.str.2025.11.010}
}

@article{bhuiya2025-41411185,
  author  = {Bhuiya, Jubo and Shibly, Abu Zaffar and Sheikh, Abdullah Md. and Tabassum, Shatera and Abdullah, Fatema Binte and Fahmida, Jerin and Tamegai, Hiro and Aritake, Shun and others},
  title   = {{Deposition of aggregated cystatin C-amyloid-β complexes and reduced cathepsin B activity modulate cerebral amyloid angiopathy pathogenesis}},
  journal = {Journal of Neuropathology \& Experimental Neurology},
  year    = {2025},
  doi     = {10.1093/jnen/nlaf138},
  pmid    = {41411185},
  url     = {https://doi.org/10.1093/jnen/nlaf138}
}

@article{fekete2025-41470875,
  author  = {Fekete, Mónika and Jarecsny, Tamás and Lehoczki, Andrea and Major, Dávid and Fazekas‐Pongor, Vince and Csípő, Tamás and Lipécz, Ágnes and Szappanos, Ágnes and others},
  title   = {{Mediterranean Diet, Polyphenols, and Neuroprotection: Mechanistic Insights into Resveratrol and Oleuropein}},
  journal = {Nutrients},
  year    = {2025},
  doi     = {10.3390/nu17243929},
  pmid    = {41470875},
  url     = {https://doi.org/10.3390/nu17243929}
}

@article{xie2025-41376284,
  author  = {Xie, Xiao‐Yong and Wang, Lu and Xie, Shi-Qi and Zhou, Gui‐Feng and Wen, Qi‐Xin and Ma, Yuanlin and Zhang, Qi‐Lei and Yan, Xiao‐Xin and others},
  title   = {{Cerebral FURIN deficiency impairs astrocytic lipophagy through ITGAV maturation}},
  journal = {Autophagy},
  year    = {2025},
  doi     = {10.1080/15548627.2025.2601039},
  pmid    = {41376284},
  url     = {https://doi.org/10.1080/15548627.2025.2601039}
}

@article{tseng2025-41359407,
  author  = {Tseng, Ping‐Tao and Zeng, Bing‐Yan and Hsu, Chih‐Wei and Suen, Mein‐Woei and Hung, Chao‐Ming and Carvalho, Andre Ferrer and Stubbs, Brendon and Chen, Yen‐Wen and others},
  title   = {{The concentration-dependent protective effects by new generation hypoglycemic agents on delirium, depression, dementia and coma: evidence from a network meta-analysis}},
  journal = {Journal of the Royal Society of Medicine},
  year    = {2025},
  doi     = {10.1177/01410768251395877},
  pmid    = {41359407},
  url     = {https://doi.org/10.1177/01410768251395877}
}

@article{hogan2025-41331940,
  author  = {Hogan, Alison L. and Kane, Madison A. and Chiu, Patrick Ka‐Chun and Richter, G. Stefan and Maurel, Cindy and Wu, Sharlynn and Scherer, Natalie M. and Don, Emily K. and others},
  title   = {{Human TDP-43 overexpression in zebrafish motor neurons triggers MND-like phenotypes through gain-of-function mechanism}},
  journal = {Acta Neuropathologica Communications},
  year    = {2025},
  doi     = {10.1186/s40478-025-02159-w},
  pmid    = {41331940},
  url     = {https://doi.org/10.1186/s40478-025-02159-w}
}

@article{heimfarth2025-41439604,
  author  = {Heimfarth, Luana and Ribeiro, Felipe Campos and Fortuna, Juliana T S and Stelzer, Gustavo Trevizani and Ferreira, Sergio Teixeira},
  title   = {{Irisin attenuates astrocyte activation and rescues memory in Alzheimer model mice}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70855_104063},
  pmid    = {41439604},
  url     = {https://doi.org/10.1002/alz70855_104063}
}

@article{spyropoulos2025-41445252,
  author  = {Spyropoulos, Demetri D. and Jenkins, Dorea P. and Carroll, Steven Lewis},
  title   = {{Mice with pR927Q and pI712M Erbb4 Mutations Develop Features of Frontotemporal Dementia and ALS}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70855_106736},
  pmid    = {41445252},
  url     = {https://doi.org/10.1002/alz70855_106736}
}

@article{halder2025-41326481,
  author  = {Halder, Debojyoti and Banerjee, Suvankar and Biswas, Swati and Adhikari, Nilanjan and Ghosh, Balaram},
  title   = {{Molecular modeling to simulation: insights into Gaussian QSAR, molecular docking, and DFT for identification of HDAC3 inhibitors for neurocognitive vascular dementia}},
  journal = {Scientific Reports},
  year    = {2025},
  doi     = {10.1038/s41598-025-28304-y},
  pmid    = {41326481},
  url     = {https://doi.org/10.1038/s41598-025-28304-y}
}

@article{jaisaaad2025-41436365,
  author  = {Jaisa-aad, Methasit and Agüero, Cinthya and Rabaneda‐Lombarte, Neus and Bianco, Celia and Melloni, Alexandra N. and Hyman, Bradley T. and Gómez‐Isla, Teresa and Brugarolas, Pedro and others},
  title   = {{Monoamine Oxidase‐B (MAO‐B) Identifies Neurotoxic Reactive Astrocytes in Alzheimer's Disease and Related Dementias}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70855_102019},
  pmid    = {41436365},
  url     = {https://doi.org/10.1002/alz70855_102019}
}

@article{hong2025-41341968,
  author  = {Hong, Jihyun and An, Hyun‐Kyu and Nam, Hyeri and Choi, Jieun and Yu, Seong-Woon},
  title   = {{Presenilin 2 regulates corticosterone-induced autophagic death of adult hippocampal neural stem cells}},
  journal = {Animal Cells and Systems},
  year    = {2025},
  doi     = {10.1080/19768354.2025.2589558},
  pmid    = {41341968},
  url     = {https://doi.org/10.1080/19768354.2025.2589558}
}

@article{shenouda2025-41447225,
  author  = {Shenouda, Marc and Robertson, Janice},
  title   = {{Small Molecule Targeting of Chaperone IP Protein Prevents and Reverses TDP‐43 Aggregation In‐vitro and In‐vivo}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70859_099984},
  pmid    = {41447225},
  url     = {https://doi.org/10.1002/alz70859_099984}
}

@article{kartono2025-41436064,
  author  = {Kartono, Bryan and Attisano, Liliana and Robertson, Janice},
  title   = {{Targeting anaplastic lymphoma kinase (ALK) alleviates synaptic dysfunction associated with C9orf72 haploinsufficiency}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70855_099957},
  pmid    = {41436064},
  url     = {https://doi.org/10.1002/alz70855_099957}
}

@article{rizuan2025-41298366,
  author  = {Rizuan, Azamat and Shenoy, Jayakrishna and Mohanty, Priyesh and dos Passos, Patricia M. and Ortiz, José F. Mercado and Bai, Leanna and Viswanathan, Renjith and Zaborowksy, Julia and others},
  title   = {{Structural details of helix-mediated multimerization of the conserved region of TDP-43 C-terminal domain}},
  journal = {Nature Communications},
  year    = {2025},
  doi     = {10.1038/s41467-025-65546-w},
  pmid    = {41298366},
  url     = {https://doi.org/10.1038/s41467-025-65546-w}
}

@article{zhang2025-41291718,
  author  = {Zhang, Minjie and You, Tongyao and Guo, Min and Zhao, Yichen and Shen, Weiwei and Jiang, Yanfeng and others},
  title   = {{Activated microglial exosomes enhance α-Synuclein internalization and accelerate neurodegeneration in lewy body dementia}},
  journal = {Journal of Nanobiotechnology},
  year    = {2025},
  doi     = {10.1186/s12951-025-03838-5},
  pmid    = {41291718},
  url     = {https://doi.org/10.1186/s12951-025-03838-5}
}

@article{wang2025-41291751,
  author  = {Wang, Xinliang and Liu, Xiaoxi and Zhang, Wenyu and Qi, Shige and Li, Jinyan and Li, Ruiyu and Guo, Jingxin and Zhang, Yifan and others},
  title   = {{Acupuncture reduces neuroinflammation and apoptosis, regulates peripheral immunity, and modulates T-cell subset distribution in vascular dementia rats}},
  journal = {Chinese Medicine},
  year    = {2025},
  doi     = {10.1186/s13020-025-01243-6},
  pmid    = {41291751},
  url     = {https://doi.org/10.1186/s13020-025-01243-6}
}

@article{gouilly2025-41287056,
  author  = {Gouilly, D. and Da-Costa, A. and Vrillon, A. and Pistono, A. and Goubeaud, M. and Bertrand, E. and Germain, J. and Ainaoui, N. and others},
  title   = {{Inhibition of p38α MAPK increases short-term astrocyte reactivity: the exploratory VIP trial in early Alzheimer's disease}},
  journal = {Journal of neuroinflammation},
  year    = {2025},
  doi     = {10.1186/s12974-025-03625-x},
  pmid    = {41287056},
  url     = {https://doi.org/10.1186/s12974-025-03625-x}
}

@article{kiran2025-41373431,
  author  = {Kiran, Sonia and Thilanka, Uvindu and Xue, Yu and Sang, Qing‐Xiang Amy},
  title   = {{Polystyrene Micro- and Nanoplastic Exposure Triggers an Activation and Stress Response in Human Astrocytes}},
  journal = {International Journal of Molecular Sciences},
  year    = {2025},
  doi     = {10.3390/ijms262311273},
  pmid    = {41373431},
  url     = {https://doi.org/10.3390/ijms262311273}
}

@article{etani2025-41261421,
  author  = {Etani, Hayato and Takatori, Sho and Wang, Wenbo and Omi, Jumpei and Amiya, Yusuke and Akahori, Aika and Watanabe, Hirotaka and Sonn, Iki and others},
  title   = {{Selective agonism of GPR34 stimulates microglial uptake and clearance of amyloid β fibrils}},
  journal = {Alzheimer s Research \& Therapy},
  year    = {2025},
  doi     = {10.1186/s13195-025-01891-8},
  pmid    = {41261421},
  url     = {https://doi.org/10.1186/s13195-025-01891-8}
}

@article{min2025-41300248,
  author  = {Min, Young and Lee, Yoon-Seob and Lee, Juwon and Keum, Da-Young and Gwag, Joo-Young and Jeon, Soyeon and Jo, Heejin and Kang, Sung-Ung},
  title   = {{The cGAS–STING Pathway in Dementia: An Emerging Mechanism of Neuroinflammation}},
  journal = {Brain Sciences},
  year    = {2025},
  doi     = {10.3390/brainsci15111241},
  pmid    = {41300248},
  url     = {https://doi.org/10.3390/brainsci15111241}
}

@article{coles2025-41238048,
  author  = {Coles, Nathan P. and Elsheikh, Suzan and Gouda, Alaa and Quesnel, Agathe and Butler, Lucy and Achadu, Ojodomo J. and Islam, Meez and Kalesh, Karunakaran and others},
  title   = {{A modified α-synuclein seed amplification assay in Lewy body dementia using Raman spectroscopy and machine learning analysis}},
  journal = {Journal of Neuroscience Methods},
  year    = {2025},
  doi     = {10.1016/j.jneumeth.2025.110617},
  pmid    = {41238048},
  url     = {https://doi.org/10.1016/j.jneumeth.2025.110617}
}

@article{gbadamosi2025-41303511,
  author  = {Gbadamosi, Monsurat T. and Romano, Giulia and Simbula, Michela and Canarutto, Giulia and Ottoboni, Linda K. and Corti, Stefania Paola and Feiguin, Fabian M.},
  title   = {{TDP-43 Regulates Rab4 Levels to Support Synaptic Vesicle Recycling and Neuromuscular Connectivity in Drosophila and Human ALS Models}},
  journal = {International Journal of Molecular Sciences},
  year    = {2025},
  doi     = {10.3390/ijms262211030},
  pmid    = {41303511},
  url     = {https://doi.org/10.3390/ijms262211030}
}

@article{choe2025-41204331,
  author  = {Choe, Kyonghwan and Ahmad, Riaz and Kang, Min Hwa and Lee, Hyeon Jin and Ahmad, Sareer and Park, Tae Ju and Kim, Myeong Ok},
  title   = {{The novel sphingolipids cP1P and P1P attenuate neuroinflammation and enhance S1PR1/Akt/mTOR signaling to mitigate cognitive decline in an Alzheimer’s disease mouse model}},
  journal = {Cell Communication and Signaling},
  year    = {2025},
  doi     = {10.1186/s12964-025-02485-5},
  pmid    = {41204331},
  url     = {https://doi.org/10.1186/s12964-025-02485-5}
}

@article{zhao2025-41198459,
  author  = {Zhao, Huimin and Li, Fangjie and Xu, Sheng and Du, Yanan and Chen, Peipei and Wei, Jie and Hao, Kun and Liu, Xiaoquan and others},
  title   = {{Restoration neurite growth by removing the blockage of endosome trafficking in Alzheimer-like mice}},
  journal = {Neurotherapeutics},
  year    = {2025},
  doi     = {10.1016/j.neurot.2025.e00777},
  pmid    = {41198459},
  url     = {https://doi.org/10.1016/j.neurot.2025.e00777}
}

@article{shaw2025-41191004,
  author  = {Shaw, Benjamin C. F. and Kaiser, Kaitlin E. and Smith, Brandon C. and Timken, J Payton and Louveau, Antoine and Williams, Jessica Lynn},
  title   = {{Astrocytes upregulate interleukin-15 in response to neuroinflammation during Alzheimer's disease}},
  journal = {Journal of Alzheimer s Disease},
  year    = {2025},
  doi     = {10.1177/13872877251393275},
  pmid    = {41191004},
  url     = {https://doi.org/10.1177/13872877251393275}
}

@article{ayata2025-1378ad15,
  author  = {Ayata, P. and Crowley, J. M. and Challman, M. F. and Sahasrabuddhe, V. and Gratuze, M. and Werneburg, S. and others},
  title   = {{Lymphoid gene expression supports neuroprotective microglia function}},
  journal = {Nature},
  year    = {2025}
}

@article{barnett2025-41188644,
  author  = {BARNETT, DANIEL H. and Zimmer, Till S. and Booraem, Caroline and Palaguachi, Fernando and Meadows, Samantha M. and Xiao, Haopeng and Wong, Man Ying and Luo, Wenjie and others},
  title   = {{Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology}},
  journal = {Nature Metabolism},
  year    = {2025},
  doi     = {10.1038/s42255-025-01390-y},
  pmid    = {41188644},
  url     = {https://doi.org/10.1038/s42255-025-01390-y}
}

@article{zong2025-41185380,
  author  = {Zong, Xuemei and Huang, Zhihai and Kong, Fanfei and Feng, Yu and Zhang, Yulan and Zou, Peibin and Lin, Hung Wen and Hess, David C. and others},
  title   = {{Clemastine ameliorates cognitive deficits in an experimental rat model of chronic cerebral hypoperfusion}},
  journal = {Journal of Cerebral Blood Flow \& Metabolism},
  year    = {2025},
  doi     = {10.1177/0271678x251382874},
  pmid    = {41185380},
  url     = {https://doi.org/10.1177/0271678x251382874}
}

@article{godrich2025-41208712,
  author  = {Godrich, Dana and Pasteris, Jeremy and Martin, Eden R. and Kunkle, Brian W. and Naj, Adam Christian and Hamilton, Kara and Wang, Hui and Lee, Wan‐Ping and others},
  title   = {{Genome‐wide association studies of TDP‐43 proteinopathy and hippocampal sclerosis reveal shared genetic associations with APOE and TMEM106B}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70760},
  pmid    = {41208712},
  url     = {https://doi.org/10.1002/alz.70760}
}

@article{hella2025-41218946,
  author  = {Hella, Mathias Nikolai Petersen and Halaas, Nathalie Bodd and Soennesyn, Hogne and Bergland, Anne Katrine and Hetland, Hanne Brit and Blennow, Kaj and Zetterberg, Henrik and Vik‐Mo, Audun Osland and others},
  title   = {{Neurogranin in cerebrospinal fluid as a marker of synaptic dysfunction in hip fracture patients with delirium: a multicentre cross-sectional study}},
  journal = {BMJ Open},
  year    = {2025},
  doi     = {10.1136/bmjopen-2024-097579},
  pmid    = {41218946},
  url     = {https://doi.org/10.1136/bmjopen-2024-097579}
}

@article{pluta2025-41245147,
  author  = {Pluta, Ryszard M.},
  title   = {{Direct and indirect role of non-coding RNAs in company with amyloid and tau protein in promoting neuroinflammation in post-ischemic brain neurodegeneration}},
  journal = {Frontiers in Cellular Neuroscience},
  year    = {2025},
  doi     = {10.3389/fncel.2025.1670462},
  pmid    = {41245147},
  url     = {https://doi.org/10.3389/fncel.2025.1670462}
}

@article{joseph2025-41174170,
  author  = {Joseph, Brian J. and Marshall, Kelly A. and Harley, Peter and Mann, Jacob R. and Alessandrini, Francesco and Vanoye, Carlos G. and Chi, Wanhao and Prudencio, Mercedes and others},
  title   = {{TDP-43-dependent mis-splicing of KCNQ2 triggers intrinsic neuronal hyperexcitability in ALS/FTD}},
  journal = {Nature Neuroscience},
  year    = {2025},
  doi     = {10.1038/s41593-025-02096-w},
  pmid    = {41174170},
  url     = {https://doi.org/10.1038/s41593-025-02096-w}
}

@article{ulku2025-41144673,
  author  = {Ulku, Irem and El Ansari, Fatima and Hancock, Mark A. and Zhou, Hedi and Cagnone, Gaël and Joyal, Jean‐Sébastien and Fisher, Teddy A. J. and Kennedy, Timothy E. and others},
  title   = {{Characterization of endothelin-converting enzyme 1 as a key enzyme in the multienzyme Aβ degradation pathway}},
  journal = {Proceedings of the National Academy of Sciences},
  year    = {2025},
  doi     = {10.1073/pnas.2507450122},
  pmid    = {41144673},
  url     = {https://doi.org/10.1073/pnas.2507450122}
}

@article{xu2025-41138884,
  author  = {Xu, Yuan and Peng, Ya and Zhi, Feng and Yang, Yilin and Li, Jiahui and Fan, Ligang and Xia, Ying and Shao, Nan},
  title   = {{Delta-opioid receptor ameliorates microglia-induced synapse loss by regulating C1q in Alzheimer disease pathology}},
  journal = {Brain Behavior and Immunity},
  year    = {2025},
  doi     = {10.1016/j.bbi.2025.106149},
  pmid    = {41138884},
  url     = {https://doi.org/10.1016/j.bbi.2025.106149}
}

@article{koide2025-41121980,
  author  = {Koide, Shingo and Ikegami, Ichiko and Hanyu, Ryutaro and Koike, Yuka Mitsuhashi and Yamagishi, Takuma and Toyama, Genri and Washida, Aya and Tada, Mari and others},
  title   = {{Quantifying subpercent nuclear TDP ‐43 loss in cells and ALS cortex using junction‐specific cryptic exon RT ‐ qPCR}},
  journal = {FEBS Letters},
  year    = {2025},
  doi     = {10.1002/1873-3468.70198},
  pmid    = {41121980},
  url     = {https://doi.org/10.1002/1873-3468.70198}
}

@article{brycesmith2025-41120751,
  author  = {Bryce-Smith, Sam and Brown, Anna‐Leigh and Chien, Max Z. Y. J. and Dattilo, Dario and Mehta, Puja R. and Mattedi, Francesca and Barattucci, Simone and Mikheenko, Alla and others},
  title   = {{TDP-43 loss induces cryptic polyadenylation in ALS/FTD}},
  journal = {Nature Neuroscience},
  year    = {2025},
  doi     = {10.1038/s41593-025-02050-w},
  pmid    = {41120751},
  url     = {https://doi.org/10.1038/s41593-025-02050-w}
}

@article{zeng2025-41120750,
  author  = {Zeng, Yi and Lovchykova, Anastasiia and Akiyama, Tetsuya and Rayner, Stephanie L. and Jawahar, Vidhya Maheswari and Liu, Chang and Sianto, Odilia and Guo, Caiwei and others},
  title   = {{TDP-43 nuclear loss in FTD/ALS causes widespread alternative polyadenylation changes}},
  journal = {Nature Neuroscience},
  year    = {2025},
  doi     = {10.1038/s41593-025-02049-3},
  pmid    = {41120750},
  url     = {https://doi.org/10.1038/s41593-025-02049-3}
}

@article{davidson2026-41109840,
  author  = {Davidson, M. H. and Szarek, M. and Scheltens, P. and Vijverberg, E. and Hsieh, A. and Ditmarsch, M. and Kling, D. and Curcio, D. and others},
  title   = {{Effect of obicetrapib, a potent cholesteryl ester transfer protein inhibitor, on p-tau217 levels in patients with cardiovascular disease}},
  journal = {The journal of prevention of Alzheimer's disease},
  year    = {2026},
  doi     = {10.1016/j.tjpad.2025.100394},
  pmid    = {41109840},
  url     = {https://doi.org/10.1016/j.tjpad.2025.100394}
}

@article{thapa2025-41210976,
  author  = {Thapa, Rashmi and Adhikari, Navin and Gautam, Sishir and Sun, Mingming and McOmie, Sierra and Davydzenka, Viyaleta and SMITH, Derek Richard and Syring, Jack and others},
  title   = {{Single-nucleus RNA sequencing reveals GABAergic vulnerability and reactive gliosis driven by loss of TDP-43}},
  journal = {iScience},
  year    = {2025},
  doi     = {10.1016/j.isci.2025.113745},
  pmid    = {41210976},
  url     = {https://doi.org/10.1016/j.isci.2025.113745}
}

@article{greda2025-41102453,
  author  = {Gręda, A. and Gomes, Jemila P. and Schmidt, Vanessa and Żurawska-Płaksej, Ewa and Fritsche‐Guenther, Raphaela and Rudolph, Ina‐Maria and Telugu, Narasimha Swamy and Cömert, Cagla and others},
  title   = {{Interaction of sortilin with apolipoprotein E3 enables neurons to use long-chain fatty acids as alternative metabolic fuel}},
  journal = {Nature Metabolism},
  year    = {2025},
  doi     = {10.1038/s42255-025-01389-5},
  pmid    = {41102453},
  url     = {https://doi.org/10.1038/s42255-025-01389-5}
}

@article{barbosa2025-41141721,
  author  = {Barbosa, Deyse Brito and de Oliveira, Lucas Matheus Gonçalves and Mendes, Géssica Oliveira and Costa, David Bacelar and de Oliveira, Tiago Alves and da Silva, Michel Pires and Damázio, Laila Cristina Moreira and Maia, Eduardo Habib Bechelane and others},
  title   = {{Silodosin as a Novel Inhibitor of Acetylcholinesterase, Butyrylcholinesterase, and BETA-Secretase 1: In Vitro and In Silico Studies}},
  journal = {ACS Omega},
  year    = {2025},
  doi     = {10.1021/acsomega.5c07084},
  pmid    = {41141721},
  url     = {https://doi.org/10.1021/acsomega.5c07084}
}

@article{espejo2025-561ddaf5,
  author  = {Espejo, Nuria H. and Feito, Alejandro and Sanchez‐Burgos, Ignacio and Garaizar, Adiran and Conde, M. M. and Rey, Antonio and Pedraza, Eduardo and Castro, Alejandro and others},
  title   = {{Compositional Control of Aging Kinetics in TDP-43 Condensates}},
  journal = {PRX Life},
  year    = {2025},
  doi     = {10.1103/w7g3-6rsd},
  url     = {https://doi.org/10.1103/w7g3-6rsd}
}

@article{chu2025-41061808,
  author  = {Chu, Min and Yue, Ailing and Nan, Haitian and Ye, Hong and Qu, Miao and Wu, Liyong},
  title   = {{Glymphatic activity is linked to the synaptic vesicle cycle pathway in frontotemporal dementia: A metabolomics study}},
  journal = {Neurobiology of Disease},
  year    = {2025},
  doi     = {10.1016/j.nbd.2025.107135},
  pmid    = {41061808},
  url     = {https://doi.org/10.1016/j.nbd.2025.107135}
}

@article{kotambail2025-d09ab756,
  author  = {Kotambail, Ananthapadmanabha and Markandeya, Yogananda Shamamandri and Mahima, R and Sukrutha, Ramya and Nimonkar, Madhura Milind and Dash, Suravi Sasmita and Prasad, Chandrajit and Chetan, Ghati Kasturirangan and others},
  title   = {{SORL1 as a Putative Candidate Gene for a Novel Recessive Form of Complicated Hereditary Spastic Paraplegia: Insights from a Deep Functional Study}},
  journal = {Clinical and Translational Neuroscience},
  year    = {2025},
  doi     = {10.3390/ctn9040046},
  url     = {https://doi.org/10.3390/ctn9040046}
}

@article{lehrer2025-41025536,
  author  = {Lehrer, Steven P. and Rheinstein, Peter H.},
  title   = {{Structure-guided Docking of Benzene-1,3-Disulfonic Acid to the ApoE-HSPG Binding Site at Arginine 136 as a Christchurch-mimetic Therapeutic Strategy for Alzheimer Disease}},
  journal = {Clinical Neuropharmacology},
  year    = {2025},
  doi     = {10.1097/wnf.0000000000000649},
  pmid    = {41025536},
  url     = {https://doi.org/10.1097/wnf.0000000000000649}
}

@article{liu2025-41013506,
  author  = {Liu, Jiahui and Zaidi, Ali Hussainy and Pike, Christian J.},
  title   = {{Microglia/macrophage-specific deletion of TLR-4 protects against neural effects of diet-induced obesity in a sexually dimorphic manner}},
  journal = {Journal of Neuroinflammation},
  year    = {2025},
  doi     = {10.1186/s12974-025-03534-z},
  pmid    = {41013506},
  url     = {https://doi.org/10.1186/s12974-025-03534-z}
}

@article{vidyadhara2025-41006254,
  author  = {Vidyadhara, D. J. and Bäckström, David C. and Chakraborty, Risha and Ruan, Jiapeng and Park, Jae-Min and Mistry, Pramod Kumar and Chandra, Sreeganga S.},
  title   = {{Synaptic vesicle endocytosis deficits underlie cognitive dysfunction in mouse models of GBA-linked Parkinson’s disease and dementia with Lewy bodies}},
  journal = {Nature Communications},
  year    = {2025},
  doi     = {10.1038/s41467-025-63444-9},
  pmid    = {41006254},
  url     = {https://doi.org/10.1038/s41467-025-63444-9}
}

@article{terrabuio2025-40993111,
  author  = {Terrabuio, E. and Pietronigro, E. C. and Bani, A. and Della Bianca, V. and Laudanna, C. and Rossi, B. and Finotti, G. and Santos-Lima, B. and Zenaro, E. and Turano, E. and Tosadori, G. and Calgaro, M. and others},
  title   = {{CD103-CD8+ T cells promote neurotoxic inflammation in Alzheimer's disease via granzyme K-PAR-1 signaling}},
  journal = {Nature Communications},
  year    = {2025},
  doi     = {10.1038/s41467-025-62405-6},
  pmid    = {40993111},
  url     = {https://doi.org/10.1038/s41467-025-62405-6}
}

@article{heavener2025-40987420,
  author  = {Heavener, Kelsey S. and Tamucci, Kirstin A. and Lee, Annie and Kabra, Khushbu and Chatila, Zena K. and Yidenk, Maedot and Bennett, David and Vardarajan, Badri Narayan and others},
  title   = {{P2RX7 modulates the function of human microglia-like cells and mediates the association of IL18 with Alzheimer's disease traits}},
  journal = {Neurobiology of Disease},
  year    = {2025},
  doi     = {10.1016/j.nbd.2025.107106},
  pmid    = {40987420},
  url     = {https://doi.org/10.1016/j.nbd.2025.107106}
}

@article{acero2025-40906020,
  author  = {Acero, Gonzalo and Rodríguez-López, Adrián and Díaz, Georgina and Esteban, Daniel and Herrera-Ángeles, Mónica and Gevorkian, Goar},
  title   = {{Splenomegaly, Spleen Amyloidosis and Neutrophil Infiltration are Present in 3xTg-AD, but not Tg-SwDI Mice}},
  journal = {NeuroMolecular Medicine},
  year    = {2025},
  doi     = {10.1007/s12017-025-08884-8},
  pmid    = {40906020},
  url     = {https://doi.org/10.1007/s12017-025-08884-8}
}

@article{garciatoledo2025-40906043,
  author  = {García-Toledo, Irene and Godoy-Corchuelo, Juan Miguel and Fernández-Beltrán, Luis C. and Ali, Zeinab and Guindo-Arroyo, Ariadna and Jiménez-Coca, Irene and Jiménez-Rodríguez, Jesús and Javaloyes-García, Karen and others},
  title   = {{TDP-43 dysregulation impairs cholesterol metabolism linked with myelination defects}},
  journal = {Acta Neuropathologica},
  year    = {2025},
  doi     = {10.1007/s00401-025-02927-x},
  pmid    = {40906043},
  url     = {https://doi.org/10.1007/s00401-025-02927-x}
}

@article{peng2025-40905723,
  author  = {Peng, Christina Yi and Maiuri, Tamara and Truant, Ray},
  title   = {{Tipping the PARylation scale: Dysregulation of PAR signaling in Huntington and neurodegenerative diseases}},
  journal = {Journal of Huntington s Disease},
  year    = {2025},
  doi     = {10.1177/18796397251372667},
  pmid    = {40905723},
  url     = {https://doi.org/10.1177/18796397251372667}
}

@article{song2025-40902587,
  author  = {Song, Z. and Xie, X. and Chen, Y. and Zhang, B. and Li, X. and Yang, Y. and Mo, W. and Zhang, J. and Xu, D.},
  title   = {{Innate immune sensing of Z-nucleic acids by ZBP1-RIPK1 axis drives neuroinflammation in Alzheimer's disease}},
  journal = {Immunity},
  year    = {2025},
  doi     = {10.1016/j.immuni.2025.07.024},
  pmid    = {40902587},
  url     = {https://doi.org/10.1016/j.immuni.2025.07.024}
}

@article{pir2025-40891506,
  author  = {Pir, Ghulam Jeelani and Buddenkotte, Joerg and Alam, Majid Ali and Own, Ahmed M. and Eck, Randall J. and Kraemer, Brian C. and Mandelkow�, Eckhard and Steinhoff, Martin S.},
  title   = {{TDP ‐43 proteinopathies and neurodegeneration: insights from Caenorhabditis elegans models}},
  journal = {FEBS Journal},
  year    = {2025},
  doi     = {10.1111/febs.70239},
  pmid    = {40891506},
  url     = {https://doi.org/10.1111/febs.70239}
}

@article{mearelli2025-40888599,
  author  = {Mearelli, Marika and Hirschberg, Insa and Weissleder, Christin and Giachino, Carmela and Maria Jose Perez, J. and Dubroux, Malvina and Provenzano, Francesca and Rizzuti, Mafalda and others},
  title   = {{C9orf72 Repeat Expansion Induces Metabolic Dysfunction in Human iPSC ‐Derived Microglia and Modulates Glial‐Neuronal Crosstalk}},
  journal = {Glia},
  year    = {2025},
  doi     = {10.1002/glia.70080},
  pmid    = {40888599},
  url     = {https://doi.org/10.1002/glia.70080}
}

@article{zheng2025-40919134,
  author  = {Zheng, Kai and Huang, He‐Zhou and Liu, Dan and Brazhe, Nadezda A. and Chen, Jiajie and Zhu, Ling‐Qiang},
  title   = {{Targeting the miR‐96‐5p/Cathepsin B Pathway to Alleviate Neuron‐Derived Neuroinflammation in Alzheimer's Disease}},
  journal = {MedComm},
  year    = {2025},
  doi     = {10.1002/mco2.70368},
  pmid    = {40919134},
  url     = {https://doi.org/10.1002/mco2.70368}
}

@article{carnicerosenabre2025-40902316,
  author  = {Carnicero-Senabre, Daniel and Barata, Mariana Afonso and Jiménez-Villegas, José and Almeida, Cláudia Guimas and Cuadrado, Antonio and Rojo, Ana Isabel},
  title   = {{NRF2 deficiency is associated with synaptic alterations and ether-linked phospholipid imbalance in the hippocampus}},
  journal = {Redox Biology},
  year    = {2025},
  doi     = {10.1016/j.redox.2025.103853},
  pmid    = {40902316},
  url     = {https://doi.org/10.1016/j.redox.2025.103853}
}

@article{peng2025-40898457,
  author  = {Peng, Shijun and Ouyang, Jia and Liu, Yezu and Wang, Lepeng and Liu, Ruen},
  title   = {{Causal effect of infectious mononucleosis on neurodegenerative diseases: A Mendelian randomization study}},
  journal = {Medicine},
  year    = {2025},
  doi     = {10.1097/md.0000000000044145},
  pmid    = {40898457},
  url     = {https://doi.org/10.1097/md.0000000000044145}
}

@article{liu2025-40876538,
  author  = {Liu, X. and Sacks, F. M. and Beck, T. and Tangney, C. C. and Willett, W. C. and Yassine, H. and Dhana, K. and Aggarwal, N. T. and others},
  title   = {{Apolipoprotein E ε4-dependent associations between carotenoids and cognitive decline: Findings from the MIND (Mediterranean-DASH Intervention for Neurodegenerative delay) randomized controlled trial}},
  journal = {The American journal of clinical nutrition},
  year    = {2025},
  doi     = {10.1016/j.ajcnut.2025.08.012},
  pmid    = {40876538},
  url     = {https://doi.org/10.1016/j.ajcnut.2025.08.012}
}

@article{lenoel2025-40858618,
  author  = {Lenoël, Isadora and Ribon, Matthieu and Lorenc, Félicie and Diebold, Aurélien and Philibert, Clémentine Eva and Robaldo, David and Badsi, Manel and Perronnet, Julianne and others},
  title   = {{ALS/FTD-linked TBK1 deficiency in microglia induces an aged-like microglial signature and drives social recognition deficits in mice}},
  journal = {Nature Communications},
  year    = {2025},
  doi     = {10.1038/s41467-025-63211-w},
  pmid    = {40858618},
  url     = {https://doi.org/10.1038/s41467-025-63211-w}
}

@article{mahulmellier2025-40858624,
  author  = {Mahul‐Mellier, Anne‐Laure and Altay, Melek Firat and Maharjan, Niran and Ait‐Bouziad, Nadine and Chiki, Anass and Jagannath, Somanath and Limorenko, Galina and Novello, Salvatore and others},
  title   = {{Differential role of C-terminal truncations on alpha-synuclein pathology and Lewy body formation}},
  journal = {npj Parkinson s Disease},
  year    = {2025},
  doi     = {10.1038/s41531-025-01084-y},
  pmid    = {40858624},
  url     = {https://doi.org/10.1038/s41531-025-01084-y}
}

@article{munni2025-40918527,
  author  = {Munni, Yeasmin Akter and Tran, Khoa Nguyen and Jeon, Seon-min and Hwang, Meeyul and Yoon, Jong-Won and Song, Young‐Ha and Oh, Tae Woo and Gum, Sang Il and others},
  title   = {{2′-Fucosyllactose mitigates cognitive deficits in Alzheimer models: targeting amyloid pathology, oxidative stress, and synaptic plasticity}},
  journal = {Frontiers in Pharmacology},
  year    = {2025},
  doi     = {10.3389/fphar.2025.1598030},
  pmid    = {40918527},
  url     = {https://doi.org/10.3389/fphar.2025.1598030}
}

@article{chia2025-40826098,
  author  = {Chia, Sook‐Yoong and Li, Mengwei and Li, Zigang and Tu, Haitao and Lee, Jolene Wei Ling and Qiu, Lifeng and Ling, Jingjing and Reynolds, Richard J. and others},
  title   = {{Single-nucleus transcriptomics reveals a distinct microglial state and increased MSR1-mediated phagocytosis as common features across dementia subtypes}},
  journal = {Genome Medicine},
  year    = {2025},
  doi     = {10.1186/s13073-025-01519-4},
  pmid    = {40826098},
  url     = {https://doi.org/10.1186/s13073-025-01519-4}
}

@article{feneberg2025-40826370,
  author  = {Feneberg, Emily and Thompson, Alexander G. and Charles, Philip D. and Vendrell, Iolanda and Kessler, Benedikt M. and Fischer, Román and Ansorge, Olaf and Gray, Elizabeth E. and others},
  title   = {{TDP-43 pathology is associated with divergent protein profiles in ALS brain and spinal cord}},
  journal = {Acta Neuropathologica Communications},
  year    = {2025},
  doi     = {10.1186/s40478-025-02084-y},
  pmid    = {40826370},
  url     = {https://doi.org/10.1186/s40478-025-02084-y}
}

@article{weiss2025-40816764,
  author  = {Weiss, Blaine E. and Gant, John C. and Lin, Ruei‐Lung and Gollihue, Jenna L. and Rogers, Colin B. and Kraner, Susan D. and Rucker, Edmund B. and Katsumata, Yuriko and others},
  title   = {{Disrupted Calcium Dynamics in Reactive Astrocytes Occur with End Feet–Arteriole Decoupling in an Amyloid Mouse Model of Alzheimer's Disease}},
  journal = {Journal of Neuroscience},
  year    = {2025},
  doi     = {10.1523/jneurosci.0349-25.2025},
  pmid    = {40816764},
  url     = {https://doi.org/10.1523/jneurosci.0349-25.2025}
}

@article{calderongarciduenas2025-40803397,
  author  = {Calderón-Garcidueñas, Lilian and Cejudo, Rubén and González-Maciel, Angélica and Reynoso-Robles, Rafael and Ramos-Morales, Andrea and Pérez-Guillé, Beatríz and Soriano‐Rosales, Rosa Eugenia and Torres‐Jardón, Ricardo},
  title   = {{Cardiovascular damage, arrhythmogenesis and overlapping Alzheimer and Parkinson's diseases and TDP-43 pathology start in pediatric and young adult urban populations: Magnetic ultrafine particulate matter and industrial particles with motion behavior play a key role}},
  journal = {Environmental Research},
  year    = {2025},
  doi     = {10.1016/j.envres.2025.122558},
  pmid    = {40803397},
  url     = {https://doi.org/10.1016/j.envres.2025.122558}
}

@article{blake2025-1cd741dd,
  author  = {Blake, Steven Michael and Baroni, Luciana and Piboolnurak, Panida and Harding, Thomas H. and Harding, Maile and Blake, Catherine Peterson},
  title   = {{Reducing Neuroinflammation and Risk of Mild Cognitive Impairment and Alzheimer’s Disease by Reducing Dietary Lipopolysaccharides, Arachidonic Acid, and Advanced Glycation End Products}},
  journal = {Journal of dementia and Alzheimer's disease},
  year    = {2025},
  doi     = {10.3390/jdad2030027},
  url     = {https://doi.org/10.3390/jdad2030027}
}

@article{du2025-40783546,
  author  = {Du, Muzi and Akerman, Suleyman C. and Fare, Charlotte M. and Ruan, Linhao and Vidensky, Svetlana and Mamedova, Lyudmila and Koo, Katie K. and Lee, Joshua Y. and others},
  title   = {{Divergent and convergent TMEM106B pathology in murine models of neurodegeneration and human disease}},
  journal = {Acta Neuropathologica Communications},
  year    = {2025},
  doi     = {10.1186/s40478-025-02087-9},
  pmid    = {40783546},
  url     = {https://doi.org/10.1186/s40478-025-02087-9}
}

@article{cordella2025-40810332,
  author  = {Cordella, Federica and Mautone, Lorenza and Salerno, Debora and Tondo, Lucrezia and Ghirga, Silvia and D’Antoni, Chiara and Parente, Erika and Romeo, Maria Anele and others},
  title   = {{Bezafibrate treatment rescues neurodevelopmental and neurodegenerative defects in 3D cortical organoid model of MAPT frontotemporal dementia}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70419},
  pmid    = {40810332},
  url     = {https://doi.org/10.1002/alz.70419}
}

@article{mercado2025-1839cdb4,
  author  = {Mercado, Francisco and Kop, Michaela and Trinh, Michelle},
  title   = {{GLP-1 receptor agonists in delirium and encephalopathies: a neuroprotective scoping review}},
  journal = {Discover Medicine},
  year    = {2025},
  doi     = {10.1007/s44337-025-00428-0},
  url     = {https://doi.org/10.1007/s44337-025-00428-0}
}

@article{demunter2025-40801602,
  author  = {de Munter, Johannes and Chaprov, Kirill and Lang, Ekkehard and Sitdikova, Kseniia and Wolters, Erik Ch. and Svirin, Evgeniy P. and Kassenova, Aliya and Tsoy, Andrey and others},
  title   = {{Neuro-Cells Mitigate Amyloid Plaque Formation and Behavioral Deficits in the APPswe/PS1dE9 Model of Alzheimer Disease While Also Reducing IL-6 Production in Human Monocytes}},
  journal = {Cells},
  year    = {2025},
  doi     = {10.3390/cells14151168},
  pmid    = {40801602},
  url     = {https://doi.org/10.3390/cells14151168}
}

@article{yamamoto2025-40707862,
  author  = {Yamamoto, Y. and Kubota, Toshiki and Noguchi, Daisuke and Saido, Takaomi C. and Ohshima, Toshio},
  title   = {{Co-Expression of Mutant Tau and α-Synuclein in Neurons Promotes Tau Phosphorylation, Neuronal Loss, and Neuroinflammation in Mouse Brain}},
  journal = {Molecular Neurobiology},
  year    = {2025},
  doi     = {10.1007/s12035-025-05248-y},
  pmid    = {40707862},
  url     = {https://doi.org/10.1007/s12035-025-05248-y}
}

@article{tabassum2025-40860138,
  author  = {Tabassum, Nishat I and Selvaraji, Sharmelee and Fan, Yibo and Lim, Vernise J.T. and Cheng, Xiangru and Peng, Xiangyuan and Arora, Aayushi and Rajeev, Vismitha and others},
  title   = {{Intermittent fasting reprograms the brain proteome to prevent synaptic degeneration and cognitive impairment in vascular dementia}},
  journal = {Theranostics},
  year    = {2025},
  doi     = {10.7150/thno.119422},
  pmid    = {40860138},
  url     = {https://doi.org/10.7150/thno.119422}
}

@article{miedema2025-40713859,
  author  = {Miedema, Suzanne S. M. and Rajicic, Ana and Mol, Merel O. and Paliukhovich, Iryna and Klaassen, Remco V. and van Buuren, Renee and Li, Ka Wan and Koopmans, Frank and others},
  title   = {{Proteomics of the temporal cortex in semantic dementia reveals brain-region specific molecular pathology and regulation of the TDP-43-ANXA11 interactome}},
  journal = {Acta Neuropathologica Communications},
  year    = {2025},
  doi     = {10.1186/s40478-025-02077-x},
  pmid    = {40713859},
  url     = {https://doi.org/10.1186/s40478-025-02077-x}
}

@article{wu2025-41268317,
  author  = {Wu, Yuying and Zhang, Zhizhen and Lian, Xiao‐Yuan},
  title   = {{Ginsenoside Rc mitigates hippocampal neuronal damage and cognitive impairment in vascular dementia rats via the pY705-Stat3/Foxo3a and pS727-Stat3/GRIM-19 pathways}},
  journal = {Journal of Ginseng Research},
  year    = {2025},
  doi     = {10.1016/j.jgr.2025.07.003},
  pmid    = {41268317},
  url     = {https://doi.org/10.1016/j.jgr.2025.07.003}
}

@article{atwal2025-40772263,
  author  = {Atwal, Manpreet Singh and Nimac, Jerneja and Čerček, Urša and Goesch, Sarah Ricarda and Goesch, Hannah Rebecca and Tziortzouda, Paraskevi and Ercolani, Tiziana and Zatorska, Anna and others},
  title   = {{Accumulation of TDP-43 causes karyopherin-α4 pathology that characterises amyotrophic lateral sclerosis}},
  journal = {Frontiers in Neuroscience},
  year    = {2025},
  doi     = {10.3389/fnins.2025.1558227},
  pmid    = {40772263},
  url     = {https://doi.org/10.3389/fnins.2025.1558227}
}

@article{beharry2025-40794874,
  author  = {Beharry, Aruun and Ward, Cian and Moore, Henry and Hoffman, Kyle S. and Chan, Patricia P. and Lowe, Todd M. and O’Donoghue, Patrick},
  title   = {{High-fidelity and differential nonsense suppression in live cells and a frontotemporal dementia allele with human transfer RNAs}},
  journal = {Nucleic Acids Research},
  year    = {2025},
  doi     = {10.1093/nar/gkaf730},
  pmid    = {40794874},
  url     = {https://doi.org/10.1093/nar/gkaf730}
}

@article{masegosa2025-40671688,
  author  = {Masegosa, Vera M. and Fritz, Elsa and Corvalán, Daniela and Rojas, Fabiola and Garcés, Polett and Navarro, Xavier and Bloms‐Funke, Petra and van Zundert, Brigitte and others},
  title   = {{Novel Dual Mechanism GRT-X Agonist Acting on Kv7 Potassium Channel/Translocator Protein Receptor Prevents Motoneuron Degeneration Following Exposure to Mouse and Human Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Astrocyte-Conditioned Media}},
  journal = {ACS Chemical Neuroscience},
  year    = {2025},
  doi     = {10.1021/acschemneuro.5c00197},
  pmid    = {40671688},
  url     = {https://doi.org/10.1021/acschemneuro.5c00197}
}

@article{schrader2025-40683561,
  author  = {Schrader, Joseph M. and Xu, Feng and Zhu, Xiaoyue and Majchrzak, Mark J. and Davis, Judianne and Van Nostrand, William E.},
  title   = {{Parenchymal and Dyshoric Fibrillar Amyloid Pathology in the rTg-D Rat Model of Cerebral Amyloid Angiopathy Type-2}},
  journal = {American Journal Of Pathology},
  year    = {2025},
  doi     = {10.1016/j.ajpath.2025.06.008},
  pmid    = {40683561},
  url     = {https://doi.org/10.1016/j.ajpath.2025.06.008}
}

@article{radanovic2025-40709649,
  author  = {Radanovic, Márcia and Neto, Carlos Eduardo Borges Passos and Monteiro, L.H.A. and Forlenza, Orestes Vicente},
  title   = {{Transactive response DNA-binding protein 43 (TDP-43) proteinopathy: the complex biological and clinical findings in limbic-predominant age-related TDP-43 encephalopathy (LATE) neuropathological changes, limbic-predominant amnestic neurodegenerative syndrome, and other mixed age-related major neurocognitive disorders}},
  journal = {Current Opinion in Psychiatry},
  year    = {2025},
  doi     = {10.1097/yco.0000000000001025},
  pmid    = {40709649},
  url     = {https://doi.org/10.1097/yco.0000000000001025}
}

@article{lin2025-40663350,
  author  = {Lin, Huan-Tang and Tsai, Yung‐Fong and Liao, Pei‐Lun and Wei, James Cheng-Chung},
  title   = {{Neurodegeneration and Stroke After Semaglutide and Tirzepatide in Patients With Diabetes and Obesity}},
  journal = {JAMA Network Open},
  year    = {2025},
  doi     = {10.1001/jamanetworkopen.2025.21016},
  pmid    = {40663350},
  url     = {https://doi.org/10.1001/jamanetworkopen.2025.21016}
}

@article{zhang2025-40624693,
  author  = {Zhang, Xudong and Xu, Yuhao and Hu, Hai and Liao, Zhenhua and Lou, Changli and Zou, Xiang},
  title   = {{Multi-omics integration reveals the role of N6-methyladenosine in epilepsy, ischemic stroke, and vascular dementia}},
  journal = {Molecular Brain},
  year    = {2025},
  doi     = {10.1186/s13041-025-01228-4},
  pmid    = {40624693},
  url     = {https://doi.org/10.1186/s13041-025-01228-4}
}

@article{boyle2025-40633679,
  author  = {Boyle, Nicholas R. and Fox, Stephanie N. and Tadepalli, Aniketh S. and Seyfried, Nicholas T. and Kukar, Thomas L. and Ramos, Eliana Marisa and Nana, Alissa L. and Spina, Salvatore and others},
  title   = {{Reduction of sphingomyelinase activity associated with progranulin deficiency and frontotemporal dementia}},
  journal = {Neurobiology of Disease},
  year    = {2025},
  doi     = {10.1016/j.nbd.2025.107024},
  pmid    = {40633679},
  url     = {https://doi.org/10.1016/j.nbd.2025.107024}
}

@article{dematteis2025-40615914,
  author  = {Dematteis, Giulia and Gong, Chunmei and Malecka, Justyna and Tonelli, Elisa and Genazzani, Armando A. and Tapella, Laura and Eleuteri, Anna Maria and Lim, Dmitry and others},
  title   = {{Rescue of protein dyshomeostasis in hippocampal astrocytes from an Alzheimer’s disease mouse model by stabilizing ER-mitochondrial interactions at a 20 nm distance}},
  journal = {Alzheimer s Research \& Therapy},
  year    = {2025},
  doi     = {10.1186/s13195-025-01793-9},
  pmid    = {40615914},
  url     = {https://doi.org/10.1186/s13195-025-01793-9}
}

@article{chen2025-40588144,
  author  = {Chen, Dongmei and Li, Ruomeng and She, Fei and Chen, Jiawen and Cho, Sang Min and Yang, Bohyun and Tian, Yuan and Guan, Le and others},
  title   = {{Saikosaponin C ameliorates tau-related pathology by modulating oxidative stress and MAPK axis in Alzheimer's disease}},
  journal = {Journal of Ethnopharmacology},
  year    = {2025},
  doi     = {10.1016/j.jep.2025.120221},
  pmid    = {40588144},
  url     = {https://doi.org/10.1016/j.jep.2025.120221}
}

@article{su2025-40595567,
  author  = {Su, Yixun and Li, Hui and Zhang, Wenjie and Tao, Shi and Wang, Qi and Zhang, Xuan and Zhou, Mi and Huang, Xiaomin and others},
  title   = {{Connexin43 hemichannel blockade turns microglia neuroprotective and mitigates cognitive deficits in a mouse model of amyloidosis}},
  journal = {Nature Communications},
  year    = {2025},
  doi     = {10.1038/s41467-025-60746-w},
  pmid    = {40595567},
  url     = {https://doi.org/10.1038/s41467-025-60746-w}
}

@article{wu2025-40595564,
  author  = {Wu, C. C. and Tsantilas, K. A. and Park, J. and Plubell, D. and Sanders, J. A. and Naicker, P. and Govender, I. and Buthelezi, S. and others},
  title   = {{Enrichment of extracellular vesicles using Mag-Net for the analysis of the plasma proteome}},
  journal = {Nature communications},
  year    = {2025},
  doi     = {10.1038/s41467-025-60595-7},
  pmid    = {40595564},
  url     = {https://doi.org/10.1038/s41467-025-60595-7}
}

@article{choi2025-40592207,
  author  = {Choi, Jae-Won and Im, Joo Young and Balakrishnan, Rengasamy},
  title   = {{Paeoniflorin exercise-mimetic potential regulates the Nrf2/HO-1/BDNF/CREB and APP/BACE-1/NF-κB/MAPK signaling pathways to reduce cognitive impairments and neuroinflammation in amnesic mouse model}},
  journal = {Biomedicine \& Pharmacotherapy},
  year    = {2025},
  doi     = {10.1016/j.biopha.2025.118299},
  pmid    = {40592207},
  url     = {https://doi.org/10.1016/j.biopha.2025.118299}
}

@article{xiao2025-40581647,
  author  = {Xiao, Weiping and Yang, Yibing and Lu, Bai and Yang, Peixuan and Li, Runze and Yang, Daizhi and Li, Fanying and Quan, Lingzhi and others},
  title   = {{Exercise-induced irisin ameliorates cognitive impairment following chronic cerebral hypoperfusion by suppressing neuroinflammation and hippocampal neuronal apoptosis}},
  journal = {Journal of Neuroinflammation},
  year    = {2025},
  doi     = {10.1186/s12974-025-03493-5},
  pmid    = {40581647},
  url     = {https://doi.org/10.1186/s12974-025-03493-5}
}

@article{zou2025-40642384,
  author  = {Zou, Xin and Cai, Luo-yang and Zhang, Jin and Yuan, Ying Shu and Song, Jie Young and Hu, Zheng and Ruan, Xiao-feng and Peng, Rui and others},
  title   = {{Mechanism of heme oxygenase-1 regulation of ferroptosis in vascular dementia}},
  journal = {Frontiers in Molecular Neuroscience},
  year    = {2025},
  doi     = {10.3389/fnmol.2025.1585079},
  pmid    = {40642384},
  url     = {https://doi.org/10.3389/fnmol.2025.1585079}
}

@article{du2025-40539508,
  author  = {Du, Miaomiao and Wang, Yujia and Wang, Xinyuan and Liu, Yifei and Xiao, Fuchuan and Zhang, Jing and Meng, Xia and Ma, Kunhe and others},
  title   = {{Age‐Related Complement C3 Drives Memory Impairments and Associated Neuropathologies in a Mouse Model}},
  journal = {Aging Cell},
  year    = {2025},
  doi     = {10.1111/acel.70145},
  pmid    = {40539508},
  url     = {https://doi.org/10.1111/acel.70145}
}

@article{zhang2025-40537012,
  author  = {Zhang, Meiyan and Lan, Xiaoyan and Gao, Yue and Li, Shen and Qiao, Guanda and Liang, Yajie and Janowski, Mirosław and Walczak, Piotr and others},
  title   = {{MCC950 suppresses NLRP3-dependent neuroinflammation and ameliorates cognitive decline in a rat model of cerebral small vessel disease}},
  journal = {Neural Regeneration Research},
  year    = {2025},
  doi     = {10.4103/nrr.nrr-d-24-01055},
  pmid    = {40537012},
  url     = {https://doi.org/10.4103/nrr.nrr-d-24-01055}
}

@article{ochneva2025-40518820,
  author  = {Ochneva, Aleksandra and Zakurazhnaya, Valeriya and Zorkina, Yana and Abramova, Olga V. and Ushakova, Valeriya M. and Tsurina, Anna M. and Golubeva, Elizaveta and Gurina, Olga Ivanovna and others},
  title   = {{The increase in TDP-43 and neurogranin blood levels at different stages of cognitive impairment in the elderly people: A cross-sectional study}},
  journal = {Journal of Alzheimer s Disease},
  year    = {2025},
  doi     = {10.1177/13872877251350385},
  pmid    = {40518820},
  url     = {https://doi.org/10.1177/13872877251350385}
}

@article{delval2025-40518671,
  author  = {del Val, Greg and Gauye, Florence and Audrain, Mickaël and Menant, Sébastien and Ratnam, Monisha and Chevalier, Elodie and Ollier, Romain and Bhatia, Daisy and others},
  title   = {{A single dose of a vectorized mAb targeting TDP-43 potently inhibits the neuropathology in a model of ALS/FTD}},
  journal = {Molecular Therapy},
  year    = {2025},
  doi     = {10.1016/j.ymthe.2025.06.026},
  pmid    = {40518671},
  url     = {https://doi.org/10.1016/j.ymthe.2025.06.026}
}

@article{kimball2025-40499086,
  author  = {Kimball, Tamara N. and Prapiadou, Savvina and Tack, Reinier W. P. and Tan, Benjamin Yong‐Qiang and Senff, Jasper Rudolf and Kourkoulis, Christina E. and Singh, Sanjula and Rosand, Jonathan M. and others},
  title   = {{Association of Leucocyte Telomere Length With Stroke, Dementia, and Late-Life Depression}},
  journal = {Neurology},
  year    = {2025},
  doi     = {10.1212/wnl.0000000000213794},
  pmid    = {40499086},
  url     = {https://doi.org/10.1212/wnl.0000000000213794}
}

@article{dellar2025-40495245,
  author  = {Dellar, Elizabeth R. and Nikel, Lara and Fowler, Stephanie L. and Vahsen, Björn Friedhelm and Dafinca, Ruxandra and Feneberg, Emily and Talbot, Kevin and Turner, Martin R. and others},
  title   = {{Extracellular vesicles in TDP-43 proteinopathies: pathogenesis and biomarker potential}},
  journal = {Molecular Neurodegeneration},
  year    = {2025},
  doi     = {10.1186/s13024-025-00859-4},
  pmid    = {40495245},
  url     = {https://doi.org/10.1186/s13024-025-00859-4}
}

@article{kochen2025-40493571,
  author  = {Kochen, Noah Nathan and Murray, Marguerite and Zafari, Sophia and Vunnam, Nagamani and Liao, Elly E. and Chen, Lihsia and Braun, Anthony R. and Sachs, Jonathan N.},
  title   = {{Fluorescence Lifetime-Based FRET Biosensors for Monitoring N Terminal Domain-Dependent Interactions of TDP-43 in Living Cells: A Novel Approach for ALS and FTD Drug Discovery}},
  journal = {ACS Chemical Neuroscience},
  year    = {2025},
  doi     = {10.1021/acschemneuro.5c00266},
  pmid    = {40493571},
  url     = {https://doi.org/10.1021/acschemneuro.5c00266}
}

@article{rullmann2025-40494919,
  author  = {Rullmann, Michael and Meyer, Philipp and Schildan, Andreas and Hoffmann, Karl‐Titus and Sabri, Osama and Tiepolt, Solveig},
  title   = {{Impact of white matter hyperintensities on α4β2 nicotinic acetylcholine receptor binding in the human brain}},
  journal = {European Journal of Nuclear Medicine and Molecular Imaging},
  year    = {2025},
  doi     = {10.1007/s00259-025-07383-z},
  pmid    = {40494919},
  url     = {https://doi.org/10.1007/s00259-025-07383-z}
}

@article{akif2025-40462117,
  author  = {Akif, Adnan and Nguyen, T.T. and Liu, Langni and Xu, Xiaotian and Kulkarni, Amol A. and Jiang, Jianxiong and Zhang, Yang and Hao, Jiukuan},
  title   = {{Targeting NLRP3 signaling with a novel sulfonylurea compound for the treatment of vascular cognitive impairment and dementia}},
  journal = {Fluids and Barriers of the CNS},
  year    = {2025},
  doi     = {10.1186/s12987-025-00665-6},
  pmid    = {40462117},
  url     = {https://doi.org/10.1186/s12987-025-00665-6}
}

@article{liao2025-40455292,
  author  = {Liao, Fan and Calvo-Rodríguez, María and Chhaya, Meha and Sefrin, Julian P. and Charych, Erik I. and Mezler, Mario and Clausznitzer, Diana and McGlame, Emily J. and others},
  title   = {{Anti-pyroglutamate-3 Aβ immunotherapy engages microglia and inhibits amyloid accumulation in transgenic mouse models of Aβ amyloidosis}},
  journal = {Acta Neuropathologica},
  year    = {2025},
  doi     = {10.1007/s00401-025-02892-5},
  pmid    = {40455292},
  url     = {https://doi.org/10.1007/s00401-025-02892-5}
}

@article{reyes2025-40495448,
  author  = {Reyes, Fernanda S. Peralta and Sommerhage, Simon and Willbold, Dieter and Schröder, Gunnar F. and Gremer, Lothar},
  title   = {{Lecanemab Binds to Transgenic Mouse Model‐Derived Amyloid‐β Fibril Structures Resembling Alzheimer's Disease Type I, Type II and Arctic Folds}},
  journal = {Neuropathology and Applied Neurobiology},
  year    = {2025},
  doi     = {10.1111/nan.70022},
  pmid    = {40495448},
  url     = {https://doi.org/10.1111/nan.70022}
}

@article{arnold2025-40454469,
  author  = {Arnold, Frederick J. and Cui, Ya and Michels, Sebastian and Colwin, Michael R. and Stockford, Cameron M. and Ye, Wenbin and Bharathi, Vidhya and Jansen‐West, Karen R. and others},
  title   = {{TDP-43 dysregulation of polyadenylation site selection is a defining feature of RNA misprocessing in amyotrophic lateral sclerosis and frontotemporal dementia}},
  journal = {Journal of Clinical Investigation},
  year    = {2025},
  doi     = {10.1172/jci182088},
  pmid    = {40454469},
  url     = {https://doi.org/10.1172/jci182088}
}

@article{bergh2025-40426231,
  author  = {Bergh, Sofia and Casadei, Nicolas and Gabery, Sanaz and Simonsson, Oskar and Duarte, João M. N. and Kirik, Deniz and Nguyen, Huu Phuc and Petersén, Åsa},
  title   = {{TDP-43 overexpression in the hypothalamus drives neuropathology, dysregulates metabolism and impairs behavior in mice}},
  journal = {Acta Neuropathologica Communications},
  year    = {2025},
  doi     = {10.1186/s40478-025-02018-8},
  pmid    = {40426231},
  url     = {https://doi.org/10.1186/s40478-025-02018-8}
}

@article{kim2025-40431734,
  author  = {Kim, Dong‐Hwi and Kim, Dong-Hwi and Kim, Jae‐Hyeong and Jeon, Min‐Tae and Kim, Kyu‐Sung and Kim, Do-Geun and Choi, In-Soo},
  title   = {{The Role of TDP-43 in SARS-CoV-2-Related Neurodegenerative Changes}},
  journal = {Viruses},
  year    = {2025},
  doi     = {10.3390/v17050724},
  pmid    = {40431734},
  url     = {https://doi.org/10.3390/v17050724}
}

@article{tzekaki2025-40427737,
  author  = {Tzekaki, Elena E. and Katsipis, Georgios and Chatzikostopoulos, Athanasios and Koutoupa, Anna and Lavrentiadou, Sophia N. and Tsolaki, Magda and Pantazaki, Αnastasia A.},
  title   = {{Neuroprotective, Antioxidant and Anti-Inflammatory Effect of Greek Pomegranate Seed Oil on N2a Neuroblastoma Cells and Mild Cognitive Impairment Patients}},
  journal = {Biology},
  year    = {2025},
  doi     = {10.3390/biology14050548},
  pmid    = {40427737},
  url     = {https://doi.org/10.3390/biology14050548}
}

@article{galeotti2025-40438379,
  author  = {Galeotti, Alice Alessandra and Santucci, Lorenzo and Klimek, Jennifer and Kabbani, Mohamed Aghyad Al and Zempel, Hans and Raffa, Vittoria},
  title   = {{Mechanical stimulation prevents impairment of axon growth and overcompensates microtubule destabilization in cellular models of Alzheimer’s disease and related Tau pathologies}},
  journal = {Frontiers in Medicine},
  year    = {2025},
  doi     = {10.3389/fmed.2025.1519628},
  pmid    = {40438379},
  url     = {https://doi.org/10.3389/fmed.2025.1519628}
}

@article{kellett2025-40340943,
  author  = {Kellett, Elise A. and Bademosi, Adekunle T. and Walker, Adam K.},
  title   = {{Molecular mechanisms and consequences of TDP-43 phosphorylation in neurodegeneration}},
  journal = {Molecular Neurodegeneration},
  year    = {2025},
  doi     = {10.1186/s13024-025-00839-8},
  pmid    = {40340943},
  url     = {https://doi.org/10.1186/s13024-025-00839-8}
}

@article{verde2025-40422183,
  author  = {Verde, Enza Maria and Secco, Valentina and Ghezzi, Andrea and Mandrioli, Jessica and Carra, Serena},
  title   = {{Molecular Mechanisms of Protein Aggregation in ALS-FTD: Focus on TDP-43 and Cellular Protective Responses}},
  journal = {Cells},
  year    = {2025},
  doi     = {10.3390/cells14100680},
  pmid    = {40422183},
  url     = {https://doi.org/10.3390/cells14100680}
}

@article{mela2025-40335161,
  author  = {Mela, Virginia and Heras, Violeta and Iešmantaitė, Monika and García‐Martín, Maria Luisa and Bernal, Manuel and Posligua-García, Joel D. and Subiri-Verdugo, Alba and Martínez‐Montoro, José Ignacio and others},
  title   = {{Microbiota fasting-related changes ameliorate cognitive decline in obesity and boost ex vivo microglial function through the gut-brain axis}},
  journal = {Gut},
  year    = {2025},
  doi     = {10.1136/gutjnl-2025-335353},
  pmid    = {40335161},
  url     = {https://doi.org/10.1136/gutjnl-2025-335353}
}

@article{zhou2025-40339618,
  author  = {Zhou, Constance Q. and Hardin, Evelyn J. and Zimmer, Till S. and Jackvony, Stephanie and BARNETT, DANIEL H. and Khobrekar, Noopur V. and Giacomelli, Elisa and Studer, Lorenz and others},
  title   = {{Neuroimmune signaling mediates astrocytic nucleocytoplasmic disruptions and stress granule formation associated with TDP-43 pathology}},
  journal = {Neurobiology of Disease},
  year    = {2025},
  doi     = {10.1016/j.nbd.2025.106939},
  pmid    = {40339618},
  url     = {https://doi.org/10.1016/j.nbd.2025.106939}
}

@article{abdellah2025-40325262,
  author  = {Abdel-Lah, Ebtsam S and Sherkawy, Hoda S. and Mohamed, Wafaa H. and Fawy, Mariam A. and Hasan, Asmaa A. and Muhammed, Asmaa A. and Taha, Amira F. and Tony, Abeer A. and others},
  title   = {{Empagliflozin and memantine combination ameliorates cognitive impairment in scopolamine + heavy metal mixture-induced Alzheimer’s disease in rats: role of AMPK/mTOR, BDNF, BACE-1, neuroinflammation, and oxidative stress}},
  journal = {Inflammopharmacology},
  year    = {2025},
  doi     = {10.1007/s10787-025-01755-5},
  pmid    = {40325262},
  url     = {https://doi.org/10.1007/s10787-025-01755-5}
}

@article{du2025-40320714,
  author  = {Du, Fang Ling and Yu, Qing and Hu, Gang and Lin, Chyuan‐Sheng and Yan, Shirley ShiDu},
  title   = {{PINK1-dependent NFKB signaling contributes to amyloid pathology in Alzheimer disease}},
  journal = {Autophagy},
  year    = {2025},
  doi     = {10.1080/15548627.2025.2463322},
  pmid    = {40320714},
  url     = {https://doi.org/10.1080/15548627.2025.2463322}
}

@article{xu2025-40394891,
  author  = {Xu, Xiaomeng and Yang, Xinyuan and Zhang, Junfang and Wang, Yan and Selim, Magdy H. and Zheng, Yingting and Shen, Ruinan and Sun, Lipeng and others},
  title   = {{Choroid plexus free‐water correlates with glymphatic function in Alzheimer's disease}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70239},
  pmid    = {40394891},
  url     = {https://doi.org/10.1002/alz.70239}
}

@article{cokdinleyen2025-40430450,
  author  = {Cokdinleyen, Melis and Valdés, Alberto and Kara, Hüseyin and Ibáñez, Elena and Cifuentes, Alejandro},
  title   = {{Neuroprotective Potential of Tetraselmis chuii Compounds: Insights into Blood–Brain Barrier Permeability and Intestinal Transport}},
  journal = {Pharmaceuticals},
  year    = {2025},
  doi     = {10.3390/ph18050629},
  pmid    = {40430450},
  url     = {https://doi.org/10.3390/ph18050629}
}

@article{sun2025-40286338,
  author  = {Sun, Xuechun and Dai, Lijun and Yuan, Xin and Cheng, Lufeng and Wang, Jing and Tian, Ye and Zhou, Lingyan},
  title   = {{Presenilin 1 M139I mutation regulates the microRNA-34a-mediated neurogenic locus notch homolog protein 1 signaling pathway in an early-onset Alzheimer disease cell model}},
  journal = {Journal of Neuropathology \& Experimental Neurology},
  year    = {2025},
  doi     = {10.1093/jnen/nlaf044},
  pmid    = {40286338},
  url     = {https://doi.org/10.1093/jnen/nlaf044}
}

@article{vizziello2025-40287755,
  author  = {Vizziello, Maria and Dellarole, Ilaria Linda and Ciullini, Arianna and Pascuzzo, Riccardo and Lombardo, Annalisa and Bellandi, Floriana and Celauro, Luigi and Battipaglia, Claudia and others},
  title   = {{TDP-43 seeding activity in the olfactory mucosa of patients with amyotrophic lateral sclerosis}},
  journal = {Molecular Neurodegeneration},
  year    = {2025},
  doi     = {10.1186/s13024-025-00833-0},
  pmid    = {40287755},
  url     = {https://doi.org/10.1186/s13024-025-00833-0}
}

@article{miller2025-40279247,
  author  = {Miller, Cameron R. and Ealy, Alyssa and Gregory, Amanda and Janarthanam, Chelva and Albers, William G and Richardson, Gabriel and Jin, Huajun and Zenitsky, Gary D. and others},
  title   = {{Pathological α-synuclein dysregulates epitranscriptomic writer METTL3 to drive neuroinflammation in microglia}},
  journal = {Cell Reports},
  year    = {2025},
  doi     = {10.1016/j.celrep.2025.115618},
  pmid    = {40279247},
  url     = {https://doi.org/10.1016/j.celrep.2025.115618}
}

@article{fohner2025-40267298,
  author  = {Fohner, Alison E. and Sitlani, Colleen M. and Jayadev, Suman and Bis, Joshua C and Trittschuh, Emily H. and Lopez, Oscar L. and Tracy, Russell P. and Psaty, Bruce M. and others},
  title   = {{Plasma TAR DNA-binding protein 43 (TDP-43) levels in a population-based cohort of older adults: The cardiovascular health study}},
  journal = {Journal of Alzheimer s Disease},
  year    = {2025},
  doi     = {10.1177/13872877251334820},
  pmid    = {40267298},
  url     = {https://doi.org/10.1177/13872877251334820}
}

@article{ashok2025-40238886,
  author  = {Ashok, Cheemala and Kimble, Amy L. and Burrage, Emily Nicole and Helming, Stephen B. and Tyburski, Jordan D. and Leclair, Nathan K. and Omar, Omar M. and Zuberi, Aamir R. and others},
  title   = {{Amyotrophic lateral sclerosis and frontotemporal dementia mutation reduces endothelial TDP-43 and causes blood-brain barrier defects}},
  journal = {Science Advances},
  year    = {2025},
  doi     = {10.1126/sciadv.ads0505},
  pmid    = {40238886},
  url     = {https://doi.org/10.1126/sciadv.ads0505}
}

@article{han2025-40239644,
  author  = {Han, Xudong and Zhang, Yichi and Petrosky, Jillian N and Bald, Sarah and Sherva, Richard and Labadorf, Adam Thomas and Cherry, Jonathan D. and Chung, Jaeyoon and others},
  title   = {{A structural haplotype in the 17q21.31 MAPT region is associated with increased risk for chronic traumatic encephalopathy endophenotypes}},
  journal = {Cell Reports Medicine},
  year    = {2025},
  doi     = {10.1016/j.xcrm.2025.102084},
  pmid    = {40239644},
  url     = {https://doi.org/10.1016/j.xcrm.2025.102084}
}

@article{kaurani2025-40216778,
  author  = {Kaurani, Lalit and Pradhan, Ranjit and Schröder, Sophie and Burkhardt, Susanne and Schuetz, Anna-Lena and Krüger, Dennis Manfred and Centeno, Tonatiuh Peña and Heutink, Peter and others},
  title   = {{A role for astrocytic miR-129-5p in frontotemporal dementia}},
  journal = {Translational Psychiatry},
  year    = {2025},
  doi     = {10.1038/s41398-025-03338-y},
  pmid    = {40216778},
  url     = {https://doi.org/10.1038/s41398-025-03338-y}
}

@article{yoon2025-40277896,
  author  = {Yoon, Chi‐Su},
  title   = {{Natural Products in the Treatment of Neuroinflammation at Microglia: Recent Trend and Features}},
  journal = {Cells},
  year    = {2025},
  doi     = {10.3390/cells14080571},
  pmid    = {40277896},
  url     = {https://doi.org/10.3390/cells14080571}
}

@article{kimura2025-40205047,
  author  = {Kimura, K. and Subramanian, A. and Yin, Z. and Khalilnezhad, A. and Wu, Y. and He, D. and Dixon, K. O. and Chitta, U. K. and Ding, X. and Adhikari, N. and Guzchenko, I. and Zhang, X. and others},
  title   = {{Immune checkpoint TIM-3 regulates microglia and Alzheimer's disease}},
  journal = {Nature},
  year    = {2025},
  doi     = {10.1038/s41586-025-08852-z},
  pmid    = {40205047},
  url     = {https://doi.org/10.1038/s41586-025-08852-z}
}

@article{corucci2025-40198794,
  author  = {Corucci, Giacomo and Vadukul, Devkee M. and Paracini, Nicoló and Laux, Valérie and Batchu, Krishna Chaithanya and Aprile, Francesco A. and Pastore, Annalisa},
  title   = {{Membrane Charge Drives the Aggregation of TDP-43 Pathological Fragments}},
  journal = {Journal of the American Chemical Society},
  year    = {2025},
  doi     = {10.1021/jacs.5c00594},
  pmid    = {40198794},
  url     = {https://doi.org/10.1021/jacs.5c00594}
}

@article{dunacka2025-40283962,
  author  = {Dunacka, Joanna and Grembecka, Beata and Majkutewicz, Irena and Wrona, Danuta},
  title   = {{Central Insulin-like Growth Factor-1 Treatment Enhances Working and Reference Memory by Reducing Neuroinflammation and Amyloid Beta Deposition in a Rat Model of Sporadic Alzheimer’s Disease}},
  journal = {Pharmaceuticals},
  year    = {2025},
  doi     = {10.3390/ph18040527},
  pmid    = {40283962},
  url     = {https://doi.org/10.3390/ph18040527}
}

@article{kaur2025-ee8ba5eb,
  author  = {Kaur, Manpreet and Shivangi, Singh and Singh, Avikramjeet and Singh, Anish},
  title   = {{Mechanisms of action of formononetin, an extract from Astragalus membranaceus medicinal plant, in ameliorating Alzheimer’s disease}},
  journal = {Exploration of neuroscience},
  year    = {2025},
  doi     = {10.37349/en.2025.100682},
  url     = {https://doi.org/10.37349/en.2025.100682}
}

@article{hou2025-40309932,
  author  = {Hou, Xu and Heckman, Michael G. and Fiesel, Fabienne C. and Koga, Shunsuke and Soto‐Beasley, Alexandra I. and Watzlawik, Jens O. and Zhao, Jing and Valentino, Rebecca R. and others},
  title   = {{Genome‐wide association analysis identifies APOE as a mitophagy modifier in Lewy body disease}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70198},
  pmid    = {40309932},
  url     = {https://doi.org/10.1002/alz.70198}
}

@article{scialo2025-40157355,
  author  = {Scialò, Carlo and Zhong, Weijia and Jagannath, Somanath and Wilkins, Oscar G. and Caredio, Davide and Hruška-Plocháň, Marián and Lurati, Flavio and Peter, Martina and others},
  title   = {{Seeded aggregation of TDP-43 induces its loss of function and reveals early pathological signatures}},
  journal = {Neuron},
  year    = {2025},
  doi     = {10.1016/j.neuron.2025.03.008},
  pmid    = {40157355},
  url     = {https://doi.org/10.1016/j.neuron.2025.03.008}
}

@article{tseriotis2025-40244061,
  author  = {Tseriotis, Vasilis‐Spyridon and Liampas, Andreas and Lazaridou, Irene-Zacharo and Karachrysafi, Sofia and Vavougios, George D. and Hadjigeorgiou, Georgios M. and Papamitsou, Theodora and Kouvelas, Dimitrios and others},
  title   = {{Repulsive Guidance Molecule-A as a Therapeutic Target Across Neurological Disorders: An Update}},
  journal = {International Journal of Molecular Sciences},
  year    = {2025},
  doi     = {10.3390/ijms26073221},
  pmid    = {40244061},
  url     = {https://doi.org/10.3390/ijms26073221}
}

@article{suk2025-40149017,
  author  = {Suk, Terry R. and Part, Caroline E. and Zhang, Jenny L. and Nguyen, Trina T. and Heer, Meghan M. and Caballero-Gómez, Alejandro and Grybas, Veronica S. and McKeever, Paul M. and others},
  title   = {{A stress-dependent TDP-43 SUMOylation program preserves neuronal function}},
  journal = {Molecular Neurodegeneration},
  year    = {2025},
  doi     = {10.1186/s13024-025-00826-z},
  pmid    = {40149017},
  url     = {https://doi.org/10.1186/s13024-025-00826-z}
}

@article{zhai2025-40151913,
  author  = {Zhai, Yanyu and Lu, Kaili and Yuan, Yuan and Zhang, Ziyao and Xue, Lixia and Zhao, Fei and Xu, Xiaofeng and Wang, Hongmei},
  title   = {{Semaglutide improves cognitive function and neuroinflammation in APP/PS1 transgenic mice by activating AMPK and inhibiting TLR4/NF-κB pathway}},
  journal = {Journal of Alzheimer s Disease},
  year    = {2025},
  doi     = {10.1177/13872877251329439},
  pmid    = {40151913},
  url     = {https://doi.org/10.1177/13872877251329439}
}

@article{wu2025-40135197,
  author  = {Wu, Yanqing and Li, Ting and Jiang, Xingjun and Ling, Jianmin and Zhao, Zaihua and Zhu, Jiahui and Chen, Chongyang and Liu, Qian and others},
  title   = {{(−)‐Epicatechin Rescues Memory Deficits by Activation of Autophagy in a Mouse Model of Tauopathies}},
  journal = {MedComm},
  year    = {2025},
  doi     = {10.1002/mco2.70144},
  pmid    = {40135197},
  url     = {https://doi.org/10.1002/mco2.70144}
}

@article{downs2025-40122182,
  author  = {Downs, Anthony M. and Kmiec, Gracianne E. and Catavero, Christina M. and Wykoff, Luke A. and McElligott, Zoé A.},
  title   = {{Loss of excitatory inputs and decreased tonic and evoked activity of locus coeruleus neurons in aged P301S mice}},
  journal = {Neurobiology of Disease},
  year    = {2025},
  doi     = {10.1016/j.nbd.2025.106883},
  pmid    = {40122182},
  url     = {https://doi.org/10.1016/j.nbd.2025.106883}
}

@article{kour2025-40183098,
  author  = {Kour, Dilpreet and Khajuria, Parul and Sharma, Kuhu and Sharma, Alpa and Sharma, Ankita and Ali, Syed Mudassir and Wazir, Priya and Ramajayan, P. and others},
  title   = {{Isobavachalcone ameliorates Alzheimer disease pathology by autophagy-mediated clearance of amyloid beta and inhibition of NLRP3 inflammasome in primary astrocytes and 5x-FAD mice}},
  journal = {Frontiers in Pharmacology},
  year    = {2025},
  doi     = {10.3389/fphar.2025.1525364},
  pmid    = {40183098},
  url     = {https://doi.org/10.3389/fphar.2025.1525364}
}

@article{alami2025-40111935,
  author  = {Alami, Mehdi and Zerif, Echarki and Khalil, Abdelouahed and Hajji, Nabil and Ramassamy, Charles and Lacombe, Guy and Laurent, Benoît and Cohen, Alan A. and others},
  title   = {{Neuroprotective effects of SGLT2 inhibitors empagliflozin and dapagliflozin on Aβ 1–42 -induced neurotoxicity and neuroinflammation in cellular models of Alzheimer's disease}},
  journal = {Journal of Alzheimer s Disease},
  year    = {2025},
  doi     = {10.1177/13872877251329474},
  pmid    = {40111935},
  url     = {https://doi.org/10.1177/13872877251329474}
}

@article{chen2025-40141445,
  author  = {Chen, Danni and Fasina, Opeyemi B. and Lin, Jiahui and Zeng, Jiayuan and Manzoor, Majid and Ohno, Hiroshi and Xiang, Lan and Qi, Jianhua},
  title   = {{TBG096 Ameliorates Memory Deficiency in AD Mouse Model via Promoting Neurogenesis and Regulation of Hsc70/HK2/PKM2/LAMP2A Signaling Pathway}},
  journal = {International Journal of Molecular Sciences},
  year    = {2025},
  doi     = {10.3390/ijms26062804},
  pmid    = {40141445},
  url     = {https://doi.org/10.3390/ijms26062804}
}

@article{beckers2025-40395983,
  author  = {Beckers, Jimmy and Van Damme, Philip},
  title   = {{The role of autophagy in the pathogenesis and treatment of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)}},
  journal = {Autophagy Reports},
  year    = {2025},
  doi     = {10.1080/27694127.2025.2474796},
  pmid    = {40395983},
  url     = {https://doi.org/10.1080/27694127.2025.2474796}
}

@article{liu2025-40183082,
  author  = {Liu, Shu and Song, Xiaochen and Sun, Yuefeng and Sun, Ailin and Li, Yang and Li, Yuyu and Chen, Jing},
  title   = {{Kai-Xin-San ameliorates mild cognitive impairment in SAMP8 mice by inhibiting neuroinflammation and pyroptosis via NLRP3/Caspase-1 pathway modulation}},
  journal = {Frontiers in Pharmacology},
  year    = {2025},
  doi     = {10.3389/fphar.2025.1528011},
  pmid    = {40183082},
  url     = {https://doi.org/10.3389/fphar.2025.1528011}
}

@article{silvallanes2025-40081780,
  author  = {Silva-Llanes, Ignacio and Rodríguez-López, Silvia and González-Naranjo, Pedro and del Sastre, Eric and López, Manuela G. and Paez, Juan Antonio and Campillo, Nuria Eugenia and Lastres‐Becker, Isabel},
  title   = {{Targeting CB2 receptor with a novel antagonist reverses cognitive decline, neurodegeneration and pyroptosis in a TAU-dependent frontotemporal dementia mouse model}},
  journal = {Brain Behavior and Immunity},
  year    = {2025},
  doi     = {10.1016/j.bbi.2025.03.008},
  pmid    = {40081780},
  url     = {https://doi.org/10.1016/j.bbi.2025.03.008}
}

@article{ordonez2025-40056267,
  author  = {Ordoñez, Willian Orlando Castillo and Palomino, Nilza Velasco and Varela, Patricia Eugenia Vélez and Martinez, Indeara and Alves, Levy Bueno and Giuliatti, Silvana},
  title   = {{Alkaloids from Caliphruria subedentata (Amaryllidaceae) as Regulators of AChE, BuChE, NMDA and GSK3 Activity: An In Vitro and In Silico Approach for Mimicking Alzheimer´s Disease}},
  journal = {Neurochemical Research},
  year    = {2025},
  doi     = {10.1007/s11064-025-04354-6},
  pmid    = {40056267},
  url     = {https://doi.org/10.1007/s11064-025-04354-6}
}

@article{serpente2025-40064379,
  author  = {Serpente, María and Delvecchio, Giuseppe and Fenoglio, Chiara and Di Consoli, Lorena and De Giudici, Giovanni and Borracci, Vittoria and Rotondo, Emanuela and Arcaro, Marina and others},
  title   = {{Differential miRNA expression in neural-enriched extracellular vesicles as potential biomarker for frontotemporal dementia and bipolar disorder}},
  journal = {Neurobiology of Disease},
  year    = {2025},
  doi     = {10.1016/j.nbd.2025.106867},
  pmid    = {40064379},
  url     = {https://doi.org/10.1016/j.nbd.2025.106867}
}

@article{mitra2025-40057796,
  author  = {Mitra, Joy and Kodavati, Manohar M. and Dharmalingam, Prakash and Guerrero, Erika N. and Rao, K. S. Jagannatha and Garruto, Ralph M. and Hegde, Muralidhar L.},
  title   = {{Endogenous TDP-43 mislocalization in a novel knock-in mouse model reveals DNA repair impairment, inflammation, and neuronal senescence}},
  journal = {Acta Neuropathologica Communications},
  year    = {2025},
  doi     = {10.1186/s40478-025-01962-9},
  pmid    = {40057796},
  url     = {https://doi.org/10.1186/s40478-025-01962-9}
}

@article{simon2025-40134937,
  author  = {Simon, Christopher and Graves, Occam Kelly and Akeju, Oluwaseun and McKay, Tina B.},
  title   = {{Elevated TDP-43 serum levels associated with postoperative delirium following major cardiac surgery}},
  journal = {Brain Behavior \& Immunity - Health},
  year    = {2025},
  doi     = {10.1016/j.bbih.2025.100974},
  pmid    = {40134937},
  url     = {https://doi.org/10.1016/j.bbih.2025.100974}
}

@article{rinne2025-40042831,
  author  = {Rinne, Juha K. A. and Huhta, Heikki I. and Pinta, Tarja Maria and Turunen, Arto and Mattila, Anne K. and Tahkola, Kyösti and Helminen, Olli and Ohtonen, Pasi Petteri and others},
  title   = {{Indocyanine Green Fluorescence Imaging in Prevention of Colorectal Anastomotic Leakage}},
  journal = {JAMA Surgery},
  year    = {2025},
  doi     = {10.1001/jamasurg.2025.0006},
  pmid    = {40042831},
  url     = {https://doi.org/10.1001/jamasurg.2025.0006}
}

@article{yang2025-40045356,
  author  = {Yang, Qu and Chen, Qi and Zhang, Kai-Bing and Liu, Yu and Zheng, Jia-Cheng and Hu, Dong-Xia and Luo, Jun},
  title   = {{Sinomenine alleviates neuroinflammation in chronic cerebral hypoperfusion by promoting M2 microglial polarization and inhibiting neuronal pyroptosis via exosomal miRNA-223-3p}},
  journal = {Acta Neuropathologica Communications},
  year    = {2025},
  doi     = {10.1186/s40478-025-01950-z},
  pmid    = {40045356},
  url     = {https://doi.org/10.1186/s40478-025-01950-z}
}

@article{bosworth2025-40048429,
  author  = {Bosworth, Alexandra P and Contreras, Minerva and Sancho, Laura and Salas, Isabel H. and Paumier, Adrien and Novak, Sammy Weiser and Manor, Uri and Allen, Nicola J.},
  title   = {{Astrocyte glypican 5 regulates synapse maturation and stabilization}},
  journal = {Cell Reports},
  year    = {2025},
  doi     = {10.1016/j.celrep.2025.115374},
  pmid    = {40048429},
  url     = {https://doi.org/10.1016/j.celrep.2025.115374}
}

@article{salama2025-ba0980c1,
  author  = {Salama, Abeer and Mohasib, Rasha M.M. and Shalaby, Eman Samy},
  title   = {{Neuroprotective role of Origanum majorana essential oil loaded in mixed surfactants based nano emulsion against lipopolysaccharide-induced Alzheimer in mice}},
  journal = {Journal of Pharmaceutical Investigation},
  year    = {2025},
  doi     = {10.1007/s40005-024-00696-5},
  url     = {https://doi.org/10.1007/s40005-024-00696-5}
}

@article{pereira2025-40036368,
  author  = {Pereira, Pedro Ervilha and De Bleecker, Jan and Bogaert, Elke and Dermaut, Bart},
  title   = {{Myopathic aggregation-prone variants in the TDP-43 prion-like domain: genetics paving the way}},
  journal = {Brain},
  year    = {2025},
  doi     = {10.1093/brain/awaf076},
  pmid    = {40036368},
  url     = {https://doi.org/10.1093/brain/awaf076}
}

@article{ding2025-39936620,
  author  = {Ding, N. and Song, Y. and Zhang, Y. and Yu, W. and Li, X. and Li, W. and Li, L.},
  title   = {{Heat-shock chaperone HSPB1 mitigates poly-glycine-induced neurodegeneration via restoration of autophagic flux}},
  journal = {Autophagy},
  year    = {2025},
  doi     = {10.1080/15548627.2025.2466144},
  pmid    = {39936620},
  url     = {https://doi.org/10.1080/15548627.2025.2466144}
}

@article{graur2025-39992414,
  author  = {Graur, Alexandru and Erickson, Natalie and Sinclair, Patricia and Nusir, Aya and Kabbani, Nadine},
  title   = {{HIV-1 gp120 Interactions with Nicotine Modulate Mitochondrial Network Properties and Amyloid Release in Microglia}},
  journal = {Neurochemical Research},
  year    = {2025},
  doi     = {10.1007/s11064-025-04357-3},
  pmid    = {39992414},
  url     = {https://doi.org/10.1007/s11064-025-04357-3}
}

@article{verde2025-39982984,
  author  = {Verde, Enza Maria and Antoniani, Francesco and Mediani, Laura and Secco, Valentina and Crotti, Samuele and Ferrara, Maria Celidea and Vinet, Jonathan and Sergeeva, Aleksandra V. and others},
  title   = {{SUMO2/3 conjugation of TDP-43 protects against aggregation}},
  journal = {Science Advances},
  year    = {2025},
  doi     = {10.1126/sciadv.adq2475},
  pmid    = {39982984},
  url     = {https://doi.org/10.1126/sciadv.adq2475}
}

@article{nadtochy2025-40149527,
  author  = {Nadtochy, Julia A. and Medvedev, Sergey P. and Grigor’eva, Elena V. and Pavlova, Sophia V. and Minina, Julia M. and Chechushkov, Anton V. and Malakhova, Anastasia A. and Коваленко, Л. В. and others},
  title   = {{Transgenic iPSC Lines with Genetically Encoded MitoTimer to Study Mitochondrial Biogenesis in Dopaminergic Neurons with Tauopathy}},
  journal = {Biomedicines},
  year    = {2025},
  doi     = {10.3390/biomedicines13030550},
  pmid    = {40149527},
  url     = {https://doi.org/10.3390/biomedicines13030550}
}

@article{talaat2025-39966086,
  author  = {Talaat, Aya N. and Ibrahim, Nehal and Ayoub, Iriny M. and Labib, Rola Milad and Singab, Abdel Nasser B.},
  title   = {{Gas Chromatography‐Mass Spectrometry Profiling of Crateva magna Leaf Lipophilic Extract and Evaluation of Its Anti‐Alzheimer and Cytotoxic Properties}},
  journal = {Chemistry \& Biodiversity},
  year    = {2025},
  doi     = {10.1002/cbdv.202402770},
  pmid    = {39966086},
  url     = {https://doi.org/10.1002/cbdv.202402770}
}

@article{delima2025-39997749,
  author  = {de Lima, Enzo Pereira and Laurindo, Lucas Fornari and Catharin, Vitor Cavallari Strozze and Direito, Rosa and Tanaka, Masaru and German, Íris Jasmin Santos and Lamas, Caroline Barbalho and Guiguer, Élen Landgraf and others},
  title   = {{Polyphenols, Alkaloids, and Terpenoids Against Neurodegeneration: Evaluating the Neuroprotective Effects of Phytocompounds Through a Comprehensive Review of the Current Evidence}},
  journal = {Metabolites},
  year    = {2025},
  doi     = {10.3390/metabo15020124},
  pmid    = {39997749},
  url     = {https://doi.org/10.3390/metabo15020124}
}

@article{nordvall2025-40054389,
  author  = {Nordvall, Gunnar and Yan, Ping and Agholme, Lotta and Lundkvist, Johan and Sandin, Johan and Biverstål, Henrik and Winblad, Bengt G. and Zetterberg, Henrik and others},
  title   = {{γ-Secretase modulation inhibits amyloid plaque formation and growth and stimulates plaque regression in amyloid precursor protein/presenilin-1 mice}},
  journal = {Journal of Pharmacology and Experimental Therapeutics},
  year    = {2025},
  doi     = {10.1016/j.jpet.2025.103400},
  pmid    = {40054389},
  url     = {https://doi.org/10.1016/j.jpet.2025.103400}
}

@article{mengr2025-39932627,
  author  = {Mengr, Anna and Šmotková, Zuzana and Pačesová, Andrea and Železná, Blanka and Kuneš, Jaroslav and Maletı́nská, Lenka},
  title   = {{Reduction of Neuroinflammation as a Common Mechanism of Action of Anorexigenic and Orexigenic Peptide Analogues in the Triple Transgenic Mouse Model of Alzheimer´s Disease}},
  journal = {Journal of Neuroimmune Pharmacology},
  year    = {2025},
  doi     = {10.1007/s11481-025-10174-w},
  pmid    = {39932627},
  url     = {https://doi.org/10.1007/s11481-025-10174-w}
}

@article{huang2025-39923578,
  author  = {Huang, Ping and Sun, Hao and Chen, Yuang and Li, Jiacheng and Peng, Yuqin and Ge, Chaowen and Zhu, Kai and Zhou, Xian and others},
  title   = {{Muscone enhances synaptic function in vascular dementia through activating BDNF-TrkB-NP2 signaling pathway}},
  journal = {International Immunopharmacology},
  year    = {2025},
  doi     = {10.1016/j.intimp.2025.114232},
  pmid    = {39923578},
  url     = {https://doi.org/10.1016/j.intimp.2025.114232}
}

@article{zhang2025-39923958,
  author  = {Zhang, Han and Bi, F.H. Tra and Zhao, Peng and Cui, Herong and Tao, Xiaojun and Zhang, Jianghua and Li, Chang and Cao, Yang and others},
  title   = {{Longan Aril polysaccharides ameliorate cognitive impairment in AD mice via restoration of the immune phagocytosis of microglia}},
  journal = {Journal of Ethnopharmacology},
  year    = {2025},
  doi     = {10.1016/j.jep.2025.119464},
  pmid    = {39923958},
  url     = {https://doi.org/10.1016/j.jep.2025.119464}
}

@article{cantone2025-39918606,
  author  = {Cantone, Anna Flavia and Burgaletto, Chiara and Di Benedetto, Giulia and Gaudio, Gabriella and Giallongo, Cesarina and Caltabiano, Rosario and Broggi, Giuseppe and Bellanca, Carlo Maria and others},
  title   = {{Rebalancing Immune Interactions within the Brain-Spleen Axis Mitigates Neuroinflammation in an Aging Mouse Model of Alzheimer’s Disease}},
  journal = {Journal of Neuroimmune Pharmacology},
  year    = {2025},
  doi     = {10.1007/s11481-025-10177-7},
  pmid    = {39918606},
  url     = {https://doi.org/10.1007/s11481-025-10177-7}
}

@article{wolner2025-39912369,
  author  = {Wolner, Sofia Hjorth and Gleerup, Helena Sophia and Musaeus, Christian Sandøe and Høgh, Peter and Ashton, Nicholas J. and Brinkmalm, Ann and Nilsson, Johanna E. and Grötschel, Lana and others},
  title   = {{Synaptosomal‐Associated Protein 25 kDA (SNAP‐25) Levels in Cerebrospinal Fluid: Implications for Alzheimer's Disease Diagnosis and Monitoring}},
  journal = {Synapse},
  year    = {2025},
  doi     = {10.1002/syn.70010},
  pmid    = {39912369},
  url     = {https://doi.org/10.1002/syn.70010}
}

@article{xie2025-39941141,
  author  = {Xie, Haihua and Jiang, Jia‐Qian and Cao, Sihui and Xu, Xuan and Zhou, Jingyin and Zhang, Ruhan and Huang, Bo and Lu, Peicheng and others},
  title   = {{The Role of Gut Microbiota-Derived Trimethylamine N-Oxide in the Pathogenesis and Treatment of Mild Cognitive Impairment}},
  journal = {International Journal of Molecular Sciences},
  year    = {2025},
  doi     = {10.3390/ijms26031373},
  pmid    = {39941141},
  url     = {https://doi.org/10.3390/ijms26031373}
}

@article{li2025-39975842,
  author  = {Li, Darwin},
  title   = {{Identifying natural inhibitors against FUS protein in dementia through machine learning, molecular docking, and dynamics simulation}},
  journal = {Frontiers in Neuroinformatics},
  year    = {2025},
  doi     = {10.3389/fninf.2024.1439090},
  pmid    = {39975842},
  url     = {https://doi.org/10.3389/fninf.2024.1439090}
}

@article{counts2025-40008917,
  author  = {Counts, Scott and Beck, John Swanson and Maloney, Bryan J. and Malek‐Ahmadi, Michael H. and Ginsberg, Stephen D. and Mufson, Elliott Jay and Lahiri, Debomoy K.},
  title   = {{Posterior cingulate cortex microRNA dysregulation differentiates cognitive resilience, mild cognitive impairment, and Alzheimer's disease}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70019},
  pmid    = {40008917},
  url     = {https://doi.org/10.1002/alz.70019}
}

@article{babaei2025-39980585,
  author  = {Babaei, Farnaz Ghayour and Saburi, Ehsan and Forouzanfar, Fatemeh and Asgari, Mohadese and Keshavarzi, Zakieh and Hajali, Vahid},
  title   = {{Effect of epigallocatechin-3-gallate (EGCG) on cognitive functioning and the expression of APP and BDNF in the hippocampus of rats with streptozotocin -induced Alzheimer-like disease}},
  journal = {Biochemistry and Biophysics Reports},
  year    = {2025},
  doi     = {10.1016/j.bbrep.2025.101930},
  pmid    = {39980585},
  url     = {https://doi.org/10.1016/j.bbrep.2025.101930}
}

@article{aljarba2025-39892578,
  author  = {Aljarba, Nada Hamad and Al-Kuraishy, Hayder Mutter and Al-Gareeb, Ali Ismail and Shokr, Mustafa M and Papadakis, Marios and Alexiou, Athanasios T. and Alruwaili, Mubarak and Alrouji, Mohammed and others},
  title   = {{The possible therapeutic role of advanced glycation end-product inhibitors in ischemic stroke}},
  journal = {Brain Research Bulletin},
  year    = {2025},
  doi     = {10.1016/j.brainresbull.2025.111236},
  pmid    = {39892578},
  url     = {https://doi.org/10.1016/j.brainresbull.2025.111236}
}

@article{coles2025-39875340,
  author  = {Coles, Nathan P. and Elsheikh, Suzan and Quesnel, Agathe and Butler, Lucy and Jennings, Claire and Tarzi, Chaimaa and Achadu, Ojodomo J. and Islam, Meez and others},
  title   = {{Molecular Insights into α-Synuclein Fibrillation: A Raman Spectroscopy and Machine Learning Approach}},
  journal = {ACS Chemical Neuroscience},
  year    = {2025},
  doi     = {10.1021/acschemneuro.4c00726},
  pmid    = {39875340},
  url     = {https://doi.org/10.1021/acschemneuro.4c00726}
}

@article{anderson2025-39864404,
  author  = {Anderson, Ashley N. and Dopler, Matthew B and Arezoumandan, Sanaz and Osei‐KanKam, Damian and Davis, Stephani A. and Ajroud, Kaouther and Lilek, Jaclyn N and Bambakadis, Eva and others},
  title   = {{Cytoplasmic expression of trans-active response DNA-binding protein-43 in aged mice display hippocampal sclerosis-like degeneration and neuronal loss with reduced lifespan}},
  journal = {Journal of Neuropathology \& Experimental Neurology},
  year    = {2025},
  doi     = {10.1093/jnen/nlae137},
  pmid    = {39864404},
  url     = {https://doi.org/10.1093/jnen/nlae137}
}

@article{cartee2025-39864627,
  author  = {Cartee, Naw May Pearl and Lee, Soo Jung and Wu, Emily and Sukpraphrute, Richard and Sukpraphrute, Catherine and Greenbaum, Jolie and Wang, Michael M.},
  title   = {{Light-chain split luciferase assay implicates pathological NOTCH3 thiol reactivity in inherited cerebral small vessel disease}},
  journal = {Journal of Biological Chemistry},
  year    = {2025},
  doi     = {10.1016/j.jbc.2025.108224},
  pmid    = {39864627},
  url     = {https://doi.org/10.1016/j.jbc.2025.108224}
}

@article{jalouli2025-39981183,
  author  = {Jalouli, Maroua and Rahman, Md. Ataur and Biswas, Partha and Rahman, Hasanur and Harrath, Abdel Halim and Lee, In-Seon and Kang, Sojin and Choi, Jinwon and others},
  title   = {{Targeting natural antioxidant polyphenols to protect neuroinflammation and neurodegenerative diseases: a comprehensive review}},
  journal = {Frontiers in Pharmacology},
  year    = {2025},
  doi     = {10.3389/fphar.2025.1492517},
  pmid    = {39981183},
  url     = {https://doi.org/10.3389/fphar.2025.1492517}
}

@article{zhu2025-39842821,
  author  = {Zhu, Sanyong and Song, Zhenfeng and Tapayan, April Sweet and Singh, Kartikey and Wang, Kuang‐Wei and Hagar, Hsiao‐Tien Chien and Zhang, Jicheng and Kim, Hyunbae and others},
  title   = {{Effects of Heparan Sulfate Trisaccharide Containing Oleanolic Acid in Attenuating Hyperphosphorylated Tau-Induced Cell Dysfunction Associated with Alzheimer’s Disease}},
  journal = {Journal of Medicinal Chemistry},
  year    = {2025},
  doi     = {10.1021/acs.jmedchem.4c02563},
  pmid    = {39842821},
  url     = {https://doi.org/10.1021/acs.jmedchem.4c02563}
}

@article{wang2025-39911382,
  author  = {Wang, Xiaohang and Wang, Qianqian and Cai, Zhensheng and Ni, Chengming and Wang, Huan and Liu, Hui and Zhao, Yusong and Wang, Jinbang and others},
  title   = {{Knockdown of PDPN in astrocytes reduces hippocampal inflammation in T2DM mice}},
  journal = {Frontiers in Immunology},
  year    = {2025},
  doi     = {10.3389/fimmu.2025.1503807},
  pmid    = {39911382},
  url     = {https://doi.org/10.3389/fimmu.2025.1503807}
}

@article{mwale2025-39827337,
  author  = {Mwale, Pharaoh Fellow and Hsieh, Cheng-Ta and Yen, Ting‐Lin and Jan, Jing‐Shiun and Taliyan, Rajeev and Yang, Chih‐Hao and Yang, Wen‐Bin},
  title   = {{Chitinase-3-like-1: a multifaceted player in neuroinflammation and degenerative pathologies with therapeutic implications}},
  journal = {Molecular Neurodegeneration},
  year    = {2025},
  doi     = {10.1186/s13024-025-00801-8},
  pmid    = {39827337},
  url     = {https://doi.org/10.1186/s13024-025-00801-8}
}

@article{hornung2025-276be469,
  author  = {Hornung, Simon and Vogl, Dominik P. and Naltsas, Denise and Volta, Beatrice Dalla and Ballmann, Markus and Marcon, Beatrice and Syed, Muhammed Muazzam Kamil and Wu, Yiyang and others},
  title   = {{Multi‐Targeting Makrozyklische Peptide als Nanomolare Inhibitoren der Selbst‐ und Kreuznukleation der Amyloiden Selbstassemblierung von α‐Synuclein}},
  journal = {Angewandte Chemie},
  year    = {2025},
  doi     = {10.1002/ange.202422834},
  url     = {https://doi.org/10.1002/ange.202422834}
}

@article{brandao2025-39813317,
  author  = {Brandão, Wesley Nogueira and Jain, Nimansha and Yin, Zhuoran and Kleemann, Kilian L. and Carpenter, Madison and Bao, Xin and Serrano, Javier Remolina and Tycksen, Eric and others},
  title   = {{Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy}},
  journal = {Science Translational Medicine},
  year    = {2025},
  doi     = {10.1126/scitranslmed.adk3690},
  pmid    = {39813317},
  url     = {https://doi.org/10.1126/scitranslmed.adk3690}
}

@article{fine2025-39872995,
  author  = {Fine, Jared M. and Kosyakovsky, Jacob and Bowe, Tate T. and Faltesek, Katherine A. and STROEBEL, BENJAMIN M. and Abrahante, Juan E. and Kelly, Michael Robert and Thompson, Elizabeth A. and others},
  title   = {{Low-dose intranasal deferoxamine modulates memory, neuroinflammation, and the neuronal transcriptome in the streptozotocin rodent model of Alzheimer’s disease}},
  journal = {Frontiers in Neuroscience},
  year    = {2025},
  doi     = {10.3389/fnins.2024.1528374},
  pmid    = {39872995},
  url     = {https://doi.org/10.3389/fnins.2024.1528374}
}

@article{palumbo2025-39819868,
  author  = {Palumbo, Laura and Nuzzo, Domenico and Girgenti, Antonella and Picone, Pasquale},
  title   = {{Mitochondria-derived vesicles: New players in the game of neurodegeneration}},
  journal = {Neural Regeneration Research},
  year    = {2025},
  doi     = {10.4103/nrr.nrr-d-24-01220},
  pmid    = {39819868},
  url     = {https://doi.org/10.4103/nrr.nrr-d-24-01220}
}

@article{ye2025-39806423,
  author  = {Ye, Jinwang and Zhong, Suyue and Wan, Huali and Guo, Xing and Yao, Xuanbao and Liu, Qiong and Chen, Liming and Wang, Jian‐Zhi and others},
  title   = {{Upregulated astrocyte HDAC7 induces Alzheimer-like tau pathologies via deacetylating transcription factor-EB and inhibiting lysosome biogenesis}},
  journal = {Molecular Neurodegeneration},
  year    = {2025},
  doi     = {10.1186/s13024-025-00796-2},
  pmid    = {39806423},
  url     = {https://doi.org/10.1186/s13024-025-00796-2}
}

@article{liu2025-39794619,
  author  = {Liu, Qianshuo and Jiang, Meixi and Wang, Zening and Meng, Jihong and Jia, Hui and Li, Jing and Lin, Jing‐Jer and Guo, Libin and others},
  title   = {{SENP1 inhibits aerobic glycolysis in Aβ1-42-incubated astrocytes by promoting PUM2 deSUMOylation}},
  journal = {Cell Biology and Toxicology},
  year    = {2025},
  doi     = {10.1007/s10565-025-09986-6},
  pmid    = {39794619},
  url     = {https://doi.org/10.1007/s10565-025-09986-6}
}

@article{wan2025-39791204,
  author  = {Wan, Tianchi and Wang, Chunkai},
  title   = {{SMOC2 promotes microglia activity and neuroinflammation in Alzheimer's disease}},
  journal = {Journal of Alzheimer s Disease},
  year    = {2025},
  doi     = {10.1177/13872877241307337},
  pmid    = {39791204},
  url     = {https://doi.org/10.1177/13872877241307337}
}

@article{hauglund2025-39788123,
  author  = {Hauglund, N. L. and Andersen, M. and Tokarska, K. and Radovanovic, T. and Kjaerby, C. and Sørensen, F. L. and Bojarowska, Z. and Untiet, V. and Ballestero, S. B. and Kolmos, M. G. and Weikop, P. and Hirase, H. and others},
  title   = {{Norepinephrine-mediated slow vasomotion drives glymphatic clearance during sleep}},
  journal = {Cell},
  year    = {2025},
  doi     = {10.1016/j.cell.2024.11.027},
  pmid    = {39788123},
  url     = {https://doi.org/10.1016/j.cell.2024.11.027}
}

@article{lana2025-39835288,
  author  = {Lana, Daniele and Ugolini, Filippo and Iovino, Ludovica and Attorre, Selene and Giovannini, Maria Grazia},
  title   = {{Astrocytes phenomics as new druggable targets in healthy aging and Alzheimer’s disease progression}},
  journal = {Frontiers in Cellular Neuroscience},
  year    = {2025},
  doi     = {10.3389/fncel.2024.1512985},
  pmid    = {39835288},
  url     = {https://doi.org/10.3389/fncel.2024.1512985}
}

@article{chami2025-39778789,
  author  = {Chami, Anna A. and Gravel, Claude and Weng, Yuan Cheng and Križ, Jasna and Julien, Jean-Pierre},
  title   = {{Virus-mediated delivery of single-chain antibody targeting TDP-43 protects against neuropathology, cognitive impairment and motor deficit caused by chronic cerebral hypoperfusion}},
  journal = {Experimental Neurology},
  year    = {2025},
  doi     = {10.1016/j.expneurol.2025.115138},
  pmid    = {39778789},
  url     = {https://doi.org/10.1016/j.expneurol.2025.115138}
}

@article{yang2025-39834810,
  author  = {Yang, Chaokai and Zhao, Enlong and Zhang, Hu and Duan, Li-Qi and Han, Xinyue and Ding, Hongli and Cheng, Yan and Wang, Dengkun and others},
  title   = {{Xixin Decoction’s novel mechanism for alleviating Alzheimer’s disease cognitive dysfunction by modulating amyloid-β transport across the blood–brain barrier to reduce neuroinflammation}},
  journal = {Frontiers in Pharmacology},
  year    = {2025},
  doi     = {10.3389/fphar.2024.1508726},
  pmid    = {39834810},
  url     = {https://doi.org/10.3389/fphar.2024.1508726}
}

@article{wang2025-39755599,
  author  = {Wang, Jie and Zhang, Mengqing and Wei, Xiaomei and Yang, Cheng and Dai, Meng and Dou, Zulin and Wang, Yonghui},
  title   = {{Effects of intermittent theta burst stimulation on cognitive and swallowing function in patients with MCI and dysphagia risk: a randomized controlled trial}},
  journal = {BMC Geriatrics},
  year    = {2025},
  doi     = {10.1186/s12877-024-05625-7},
  pmid    = {39755599},
  url     = {https://doi.org/10.1186/s12877-024-05625-7}
}

@article{coles2025-40226383,
  author  = {Coles, Nathan P. and Elsheikh, Suzan and Quesnel, Agathe and Butler, Lucy and Achadu, Ojodomo J. and Islam, Meez and Kalesh, Karunakaran and Occhipinti, Annalisa and others},
  title   = {{Alpha-synuclein aggregation induces prominent cellular lipid changes as revealed by Raman spectroscopy and machine learning analysis}},
  journal = {Brain Communications},
  year    = {2025},
  doi     = {10.1093/braincomms/fcaf133},
  pmid    = {40226383},
  url     = {https://doi.org/10.1093/braincomms/fcaf133}
}

@article{coleman2025-39862881,
  author  = {Coleman, K. K. L. and Berry, S. and Cummings, J. and Hsiung, G. R. and Laforce, R. and Huey, E. and Ducharme, S. and Tartaglia, M. C. and Mendez, M. F. and Onyike, C. and others},
  title   = {{Intranasal oxytocin for apathy in people with frontotemporal dementia (FOXY): a multicentre, randomised, double-blind, placebo-controlled, adaptive, crossover, phase 2a/2b superiority trial}},
  journal = {The Lancet Neurology},
  year    = {2025},
  doi     = {10.1016/S1474-4422(24)00456-3},
  pmid    = {39862881},
  url     = {https://doi.org/10.1016/S1474-4422(24)00456-3}
}

@article{demeyer2025-40620474,
  author  = {De Meyer, Steffi and Alali, Soha and Laroy, Maarten and Casteele, Thomas Vande and Van Cauwenberge, Margot and Goossens, Julie and De Rocker, Charlotte and Vanbrabant, Jeroen and others},
  title   = {{Plasma vesicle-associated membrane protein 2 and glial fibrillary acidic protein associate with synaptic density in older adults without dementia}},
  journal = {Brain Communications},
  year    = {2025},
  doi     = {10.1093/braincomms/fcaf207},
  pmid    = {40620474},
  url     = {https://doi.org/10.1093/braincomms/fcaf207}
}

@article{hong2025-bfcd5fd0,
  author  = {Hong and Jihyun and An and Hyun-kyu and Nam and Hyeri and Choi and Jieun and others},
  title   = {{Presenilin 2 regulates corticosterone-induced autophagic death of adult hippocampal neural stem cells}},
  journal = {Figshare},
  year    = {2025},
  doi     = {10.6084/m9.figshare.30753007},
  url     = {https://doi.org/10.6084/m9.figshare.30753007}
}

@article{hong2025-da1417b6,
  author  = {Hong and Jihyun and An and Hyun-kyu and Nam and Hyeri and Choi and Jieun and others},
  title   = {{Presenilin 2 regulates corticosterone-induced autophagic death of adult hippocampal neural stem cells}},
  journal = {Figshare},
  year    = {2025},
  doi     = {10.6084/m9.figshare.30753007.v1},
  url     = {https://doi.org/10.6084/m9.figshare.30753007.v1}
}

@article{sisman2025-40476457,
  author  = {Şişman, Aysel Büşra and Merve, Savaş and Koral, Gizem and Bayar, Muhammet Duran and Yildiz, Oğuz and Mutlu, Aytül and Yılmaz, Vuslat and Tüzün, Erdem and others},
  title   = {{Treatment-resistant patients with focal epilepsy of unknown cause display reduced neurogranin levels: a preliminary study}},
  journal = {Ideggyógyászati Szemle},
  year    = {2025},
  doi     = {10.18071/isz.78.0163},
  pmid    = {40476457},
  url     = {https://doi.org/10.18071/isz.78.0163}
}

@article{peng2025-39731912,
  author  = {Peng, X. and Sun, B. and Tang, C. and Shi, C. and Xie, X. and Wang, X. and Jiang, D. and Li, S. and others},
  title   = {{HMOX1-LDHB interaction promotes ferroptosis by inducing mitochondrial dysfunction in foamy macrophages during advanced atherosclerosis}},
  journal = {Developmental cell},
  year    = {2025},
  doi     = {10.1016/j.devcel.2024.12.011},
  pmid    = {39731912},
  url     = {https://doi.org/10.1016/j.devcel.2024.12.011}
}

@article{zou2024-39545066,
  author  = {Zou, Y. and Wang, C. and Li, H. and Zhong, M. and Lin, J. and Hu, Y. and Chen, Z. and Gan, C. L.},
  title   = {{Epileptic seizures induced by pentylenetetrazole kindling accelerate Alzheimer-like neuropathology in 5×FAD mice}},
  journal = {Frontiers in pharmacology},
  year    = {2024},
  doi     = {10.3389/fphar.2024.1500105},
  pmid    = {39545066},
  url     = {https://doi.org/10.3389/fphar.2024.1500105}
}

@article{demoraes2024-39596576,
  author  = {de Moraes, Ruan Carlos Macêdo and Roth, Jonathan R. and Mao, Hailey and Crawley, Savannah R. and Xu, Brittney P. and Watson, John C. and Melkani, Girish C.},
  title   = {{Apolipoprotein E Induces Lipid Accumulation Through Dgat2 That Is Prevented with Time-Restricted Feeding in Drosophila}},
  journal = {Genes},
  year    = {2024},
  doi     = {10.3390/genes15111376},
  pmid    = {39596576},
  url     = {https://doi.org/10.3390/genes15111376}
}

@article{zhang2024-39448576,
  author  = {Zhang, R. and Ohshima, M. and Brodin, D. and Wang, Y. and Morancé, A. and Schultzberg, M. and Chen, G. and Johansson, J.},
  title   = {{Intravenous chaperone treatment of late-stage Alzheimer´s disease (AD) mouse model affects amyloid plaque load, reactive gliosis and AD-related genes}},
  journal = {Translational psychiatry},
  year    = {2024},
  doi     = {10.1038/s41398-024-03161-x},
  pmid    = {39448576},
  url     = {https://doi.org/10.1038/s41398-024-03161-x}
}

@article{zhang2025-39193909,
  author  = {Zhang, Z. and Chen, S. and Jun, S. and Xu, X. and Hong, Y. and Yang, X. and Zou, L. and Song, Y. Q. and others},
  title   = {{MLKL-USP7-UBA52 signaling is indispensable for autophagy in brain through maintaining ubiquitin homeostasis}},
  journal = {Autophagy},
  year    = {2025},
  doi     = {10.1080/15548627.2024.2395727},
  pmid    = {39193909},
  url     = {https://doi.org/10.1080/15548627.2024.2395727}
}

@article{park2024-39255397,
  author  = {Park, G. and Kadyan, S. and Hochuli, N. and Salazar, G. and Laitano, O. and Chakrabarty, P. and Efron, P. A. and Zafar, M. A. and others},
  title   = {{An Enteric Bacterial Infection Triggers Neuroinflammation and Neurobehavioral Impairment in 3xTg-AD Transgenic Mice}},
  journal = {The Journal of infectious diseases},
  year    = {2024},
  doi     = {10.1093/infdis/jiae165},
  pmid    = {39255397},
  url     = {https://doi.org/10.1093/infdis/jiae165}
}

@article{duggan2024-39143319,
  author  = {Duggan, M. R. and Peng, Z. and Sipilä, P. N. and Lindbohm, J. V. and Chen, J. and Lu, Y. and Davatzikos, C. and Erus, G. and others},
  title   = {{Proteomics identifies potential immunological drivers of postinfection brain atrophy and cognitive decline}},
  journal = {Nature aging},
  year    = {2024},
  doi     = {10.1038/s43587-024-00682-4},
  pmid    = {39143319},
  url     = {https://doi.org/10.1038/s43587-024-00682-4}
}

@article{scheiblich2024-39059388,
  author  = {Scheiblich, H. and Eikens, F. and Wischhof, L. and Opitz, S. and Jüngling, K. and Cserép, C. and Schmidt, S. V. and Lambertz, J. and others},
  title   = {{Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes}},
  journal = {Neuron},
  year    = {2024},
  doi     = {10.1016/j.neuron.2024.06.029},
  pmid    = {39059388},
  url     = {https://doi.org/10.1016/j.neuron.2024.06.029}
}

@article{wang2024-38942796,
  author  = {Wang, Y. and Chen, W. and Qiao, S. and Zou, H. and Yu, X. J. and Yang, Y. and Li, Z. and Wang, J. and others},
  title   = {{Lipid droplet accumulation mediates macrophage survival and Treg recruitment via the CCL20/CCR6 axis in human hepatocellular carcinoma}},
  journal = {Cellular \& molecular immunology},
  year    = {2024},
  doi     = {10.1038/s41423-024-01199-x},
  pmid    = {38942796},
  url     = {https://doi.org/10.1038/s41423-024-01199-x}
}

@article{driscoll2024-39030746,
  author  = {Driscoll, I. F. and Lose, S. and Ma, Y. and Bendlin, B. B. and Gallagher, C. and Johnson, S. C. and Asthana, S. and Hermann, B. and others},
  title   = {{KLOTHO KL-VS heterozygosity is associated with diminished age-related neuroinflammation, neurodegeneration, and synaptic dysfunction in older cognitively unimpaired adults}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2024},
  doi     = {10.1002/alz.13912},
  pmid    = {39030746},
  url     = {https://doi.org/10.1002/alz.13912}
}

@article{brennan2024-38865485,
  author  = {Brennan, F. H. and Swarts, E. A. and Kigerl, K. A. and Mifflin, K. A. and Guan, Z. and Noble, B. T. and Wang, Y. and Witcher, K. G. and others},
  title   = {{Microglia promote maladaptive plasticity in autonomic circuitry after spinal cord injury in mice}},
  journal = {Science translational medicine},
  year    = {2024},
  doi     = {10.1126/scitranslmed.adi3259},
  pmid    = {38865485},
  url     = {https://doi.org/10.1126/scitranslmed.adi3259}
}

@article{chen2024-38747498,
  author  = {Chen, X. Q. and Becker, A. and Albay, R. and Nguyen, P. D. and Karachentsev, D. and Roberts, A. J. and Rynearson, K. D. and Tanzi, R. E. and others},
  title   = {{γ-Secretase Modulator BPN15606 Reduced Aβ42 and Aβ40 and Countered Alzheimer-Related Pathologies in a Mouse Model of Down Syndrome}},
  journal = {Annals of neurology},
  year    = {2024},
  doi     = {10.1002/ana.26958},
  pmid    = {38747498},
  url     = {https://doi.org/10.1002/ana.26958}
}

@article{nameni2024-38700073,
  author  = {Nameni, G. and Jazayeri, S. and Fatahi, S. and Jamshidi, S. and Zaroudi, M.},
  title   = {{Soluble receptor of advanced glycation end product as a biomarker in neurocognitive and neuropsychiatric disorders: A meta-analysis of controlled studies}},
  journal = {European journal of clinical investigation},
  year    = {2024},
  doi     = {10.1111/eci.14232},
  pmid    = {38700073},
  url     = {https://doi.org/10.1111/eci.14232}
}

@article{jiang2024-38649866,
  author  = {Jiang, S. and Cai, G. and Yang, Z. and Shi, H. and Zeng, H. and Ye, Q. and Hu, Z. and Wang, Z.},
  title   = {{Biomimetic Nanovesicles as a Dual Gene Delivery System for the Synergistic Gene Therapy of Alzheimer's Disease}},
  journal = {ACS nano},
  year    = {2024},
  doi     = {10.1021/acsnano.3c13150},
  pmid    = {38649866},
  url     = {https://doi.org/10.1021/acsnano.3c13150}
}

@article{frye2024-38636565,
  author  = {Frye, B. M. and Negrey, J. D. and Johnson, C. S. C. and Kim, J. and Barcus, R. A. and Lockhart, S. N. and Whitlow, C. T. and Chiou, K. L. and others},
  title   = {{Mediterranean diet protects against a neuroinflammatory cortical transcriptome: Associations with brain volumetrics, peripheral inflammation, social isolation, and anxiety in nonhuman primates (Macaca fascicularis)}},
  journal = {Brain, behavior, and immunity},
  year    = {2024},
  doi     = {10.1016/j.bbi.2024.04.016},
  pmid    = {38636565},
  url     = {https://doi.org/10.1016/j.bbi.2024.04.016}
}

@article{yashaswini2024-38508241,
  author  = {Yashaswini, C. N. and Qin, T. and Bhattacharya, D. and Amor, C. and Lowe, S. and Lujambio, A. and Wang, S. and Friedman, S. L.},
  title   = {{Phenotypes and ontogeny of senescent hepatic stellate cells in metabolic dysfunction-associated steatohepatitis}},
  journal = {Journal of hepatology},
  year    = {2024},
  doi     = {10.1016/j.jhep.2024.03.014},
  pmid    = {38508241},
  url     = {https://doi.org/10.1016/j.jhep.2024.03.014}
}

@article{seddighi2024-38277467,
  author  = {Seddighi, S. and Qi, Y. A. and Brown, A. L. and Wilkins, O. G. and Bereda, C. and Belair, C. and Zhang, Y. J. and Prudencio, M. and others},
  title   = {{Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD}},
  journal = {Science translational medicine},
  year    = {2024},
  doi     = {10.1126/scitranslmed.adg7162},
  pmid    = {38277467},
  url     = {https://doi.org/10.1126/scitranslmed.adg7162}
}

@article{dzobo2024-38269588,
  author  = {Dzobo, K. E. and Cupido, A. J. and Mol, B. M. and Stiekema, L. C. A. and Versloot, M. and Winkelmeijer, M. and Peter, J. and Pennekamp, A. M. and others},
  title   = {{Diacylglycerols and Lysophosphatidic Acid, Enriched on Lipoprotein(a), Contribute to Monocyte Inflammation}},
  journal = {Arteriosclerosis, thrombosis, and vascular biology},
  year    = {2024},
  doi     = {10.1161/atvbaha.123.319937},
  pmid    = {38269588},
  url     = {https://doi.org/10.1161/atvbaha.123.319937}
}

@article{ali2024-36567300,
  author  = {Ali, M. U. and Anwar, L. and Ali, M. H. and Iqubal, M. K. and Iqubal, A. and Baboota, S. and Ali, J.},
  title   = {{Signalling Pathways Involved in Microglial Activation in Alzheimer's Disease and Potential Neuroprotective Role of Phytoconstituents}},
  journal = {CNS \& neurological disorders drug targets},
  year    = {2024},
  doi     = {10.2174/1871527322666221223091529},
  pmid    = {36567300},
  url     = {https://doi.org/10.2174/1871527322666221223091529}
}

@article{terzioglu2023-38017562,
  author  = {Terzioglu, G. and Young-Pearse, T. L.},
  title   = {{Microglial function, INPP5D/SHIP1 signaling, and NLRP3 inflammasome activation: implications for Alzheimer's disease}},
  journal = {Molecular neurodegeneration},
  year    = {2023},
  doi     = {10.1186/s13024-023-00674-9},
  pmid    = {38017562},
  url     = {https://doi.org/10.1186/s13024-023-00674-9}
}

@article{smart2023-37314125,
  author  = {Smart, C. D. and Fehrenbach, D. J. and Wassenaar, J. W. and Agrawal, V. and Fortune, N. L. and Dixon, D. D. and Cottam, M. A. and Hasty, A. H. and others},
  title   = {{Immune profiling of murine cardiac leukocytes identifies triggering receptor expressed on myeloid cells 2 as a novel mediator of hypertensive heart failure}},
  journal = {Cardiovascular research},
  year    = {2023},
  doi     = {10.1093/cvr/cvad093},
  pmid    = {37314125},
  url     = {https://doi.org/10.1093/cvr/cvad093}
}

@article{ocanas2023-37587511,
  author  = {Ocañas, SR. and Pham, K. D. and Cox, J. E. J. and Keck, A. W. and Ko, S. and Ampadu, F. A. and Porter, H. L. and Ansere, V. A. and others},
  title   = {{Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer's disease}},
  journal = {Journal of neuroinflammation},
  year    = {2023},
  doi     = {10.1186/s12974-023-02870-2},
  pmid    = {37587511},
  url     = {https://doi.org/10.1186/s12974-023-02870-2}
}

@article{demuynck2024-37535809,
  author  = {De Muynck, K. and Heyerick, L. and De Ponti, F. F. and Vanderborght, B. and Meese, T. and Van Campenhout, S. and Baudonck, L. and Gijbels, E. and others},
  title   = {{Osteopontin characterizes bile duct-associated macrophages and correlates with liver fibrosis severity in primary sclerosing cholangitis}},
  journal = {Hepatology (Baltimore, Md.)},
  year    = {2024},
  doi     = {10.1097/hep.0000000000000557},
  pmid    = {37535809},
  url     = {https://doi.org/10.1097/hep.0000000000000557}
}

@article{patani2023-37308616,
  author  = {Patani, R. and Hardingham, G. E. and Liddelow, S. A.},
  title   = {{Functional roles of reactive astrocytes in neuroinflammation and neurodegeneration}},
  journal = {Nature reviews. Neurology},
  year    = {2023},
  doi     = {10.1038/s41582-023-00822-1},
  pmid    = {37308616},
  url     = {https://doi.org/10.1038/s41582-023-00822-1}
}

@article{feng2023-37351177,
  author  = {Feng, S. and Wu, C. and Zou, P. and Deng, Q. and Chen, Z. and Li, M. and Zhu, L. and Li, F. and others},
  title   = {{High-intensity interval training ameliorates Alzheimer's disease-like pathology by regulating astrocyte phenotype-associated AQP4 polarization}},
  journal = {Theranostics},
  year    = {2023},
  doi     = {10.7150/thno.81951},
  pmid    = {37351177},
  url     = {https://doi.org/10.7150/thno.81951}
}

@article{udeochu2023-37095396,
  author  = {Udeochu, J. C. and Amin, S. and Huang, Y. and Fan, L. and Torres, E. R. S. and Carling, G. K. and Liu, B. and McGurran, H. and others},
  title   = {{Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience}},
  journal = {Nature neuroscience},
  year    = {2023},
  doi     = {10.1038/s41593-023-01315-6},
  pmid    = {37095396},
  url     = {https://doi.org/10.1038/s41593-023-01315-6}
}

@article{micheli2023-37049607,
  author  = {Micheli, L. and Bertini, L. and Bonato, A. and Villanova, N. and Caruso, C. and Caruso, M. and Bernini, R. and Tirone, F.},
  title   = {{Role of Hydroxytyrosol and Oleuropein in the Prevention of Aging and Related Disorders: Focus on Neurodegeneration, Skeletal Muscle Dysfunction and Gut Microbiota}},
  journal = {Nutrients},
  year    = {2023},
  doi     = {10.3390/nu15071767},
  pmid    = {37049607},
  url     = {https://doi.org/10.3390/nu15071767}
}

@article{zhou2023-36989373,
  author  = {Zhou, J. and Wade, S. D. and Graykowski, D. and Xiao, M. F. and Zhao, B. and Giannini, L. A. A. and Hanson, J. E. and van Swieten, J. C. and others},
  title   = {{The neuronal pentraxin Nptx2 regulates complement activity and restrains microglia-mediated synapse loss in neurodegeneration}},
  journal = {Science translational medicine},
  year    = {2023},
  doi     = {10.1126/scitranslmed.adf0141},
  pmid    = {36989373},
  url     = {https://doi.org/10.1126/scitranslmed.adf0141}
}

@article{hou2023-36952346,
  author  = {Hou, J. and Zhou, Y. and Cai, Z. and Terekhova, M. and Swain, A. and Andhey, P. S. and Guimaraes, R. M. and Ulezko Antonova, A. and others},
  title   = {{Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination}},
  journal = {Cell reports},
  year    = {2023},
  doi     = {10.1016/j.celrep.2023.112293},
  pmid    = {36952346},
  url     = {https://doi.org/10.1016/j.celrep.2023.112293}
}

@article{kamaruzzaman2023-36959856,
  author  = {Kamaruzzaman, M. A. and Romli, M. H. and Abas, R. and Vidyadaran, S. and Hidayat Baharuldin, M. T. and Nasaruddin, M. L. and Thirupathirao, V. and Sura, S. and others},
  title   = {{Regulatory role of the endocannabinoid system on glial cells toward cognitive function in Alzheimer's disease: A systematic review and meta-analysis of animal studies}},
  journal = {Frontiers in pharmacology},
  year    = {2023},
  doi     = {10.3389/fphar.2023.1053680},
  pmid    = {36959856},
  url     = {https://doi.org/10.3389/fphar.2023.1053680}
}

@article{bancaro2023-36868226,
  author  = {Bancaro, N. and Calì, B. and Troiani, M. and Elia, A. R. and Arzola, R. A. and Attanasio, G. and Lai, P. and Crespo, M. and others},
  title   = {{Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer}},
  journal = {Cancer cell},
  year    = {2023},
  doi     = {10.1016/j.ccell.2023.02.004},
  pmid    = {36868226},
  url     = {https://doi.org/10.1016/j.ccell.2023.02.004}
}

@article{greve2023-35348636,
  author  = {Greve, H. J. and Dunbar, A. L. and Lombo, C. G. and Ahmed, C. and Thang, M. and Messenger, E. J. and Mumaw, C. L. and Johnson, J. A. and others},
  title   = {{The bidirectional lung brain-axis of amyloid-β pathology: ozone dysregulates the peri-plaque microenvironment}},
  journal = {Brain : a journal of neurology},
  year    = {2023},
  doi     = {10.1093/brain/awac113},
  pmid    = {35348636},
  url     = {https://doi.org/10.1093/brain/awac113}
}

@article{giudici2023-36508390,
  author  = {Giudici, K. V. and de Souto Barreto, P. and Guyonnet, S. and Morley, J. E. and Nguyen, A. D. and Aggarwal, G. and Parini, A. and Li, Y. and others},
  title   = {{TNFR-1 and GDF-15 Are Associated With Plasma Neurofilament Light Chain and Progranulin Among Community-Dwelling Older Adults: A Secondary Analysis of the MAPT Study}},
  journal = {The journals of gerontology. Series A, Biological sciences and medical sciences},
  year    = {2023},
  doi     = {10.1093/gerona/glac244},
  pmid    = {36508390},
  url     = {https://doi.org/10.1093/gerona/glac244}
}

@article{church2022-36517889,
  author  = {Church, K. A. and Rodriguez, D. and Vanegas, D. and Gutierrez, I. L. and Cardona, S. M. and Madrigal, J. L. M. and Kaur, T. and Cardona, A. E.},
  title   = {{Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina}},
  journal = {Journal of neuroinflammation},
  year    = {2022},
  doi     = {10.1186/s12974-022-02659-9},
  pmid    = {36517889},
  url     = {https://doi.org/10.1186/s12974-022-02659-9}
}

@article{kalyan2022-36552802,
  author  = {Kalyan, M. and Tousif, A. H. and Sonali, S. and Vichitra, C. and Sunanda, T. and Praveenraj, S. S. and Ray, B. and Gorantla, V. R. and others},
  title   = {{Role of Endogenous Lipopolysaccharides in Neurological Disorders}},
  journal = {Cells},
  year    = {2022},
  doi     = {10.3390/cells11244038},
  pmid    = {36552802},
  url     = {https://doi.org/10.3390/cells11244038}
}

@article{saloner2022-36041868,
  author  = {Saloner, R. and Fonseca, C. and Paolillo, E. W. and Asken, B. M. and Djukic, N. A. and Lee, S. and Nilsson, J. and Brinkmalm, A. and others},
  title   = {{Combined Effects of Synaptic and Axonal Integrity on Longitudinal Gray Matter Atrophy in Cognitively Unimpaired Adults}},
  journal = {Neurology},
  year    = {2022},
  doi     = {10.1212/wnl.0000000000201165},
  pmid    = {36041868},
  url     = {https://doi.org/10.1212/wnl.0000000000201165}
}

@article{lu2022-36411661,
  author  = {Lu, Y. P. and Wu, H. W. and Zhu, T. and Li, X. T. and Zuo, J. and Hasan, A. A. and Reichetzeder, C. and Delic, D. and others},
  title   = {{Empagliflozin reduces kidney fibrosis and improves kidney function by alternative macrophage activation in rats with 5/6-nephrectomy}},
  journal = {Biomedicine \& pharmacotherapy = Biomedecine \& pharmacotherapie},
  year    = {2022},
  doi     = {10.1016/j.biopha.2022.113947},
  pmid    = {36411661},
  url     = {https://doi.org/10.1016/j.biopha.2022.113947}
}

@article{faridar2022-36180898,
  author  = {Faridar, A. and Vasquez, M. and Thome, A. D. and Yin, Z. and Xuan, H. and Wang, J. H. and Wen, S. and Li, X. and others},
  title   = {{Ex vivo expanded human regulatory T cells modify neuroinflammation in a preclinical model of Alzheimer's disease}},
  journal = {Acta neuropathologica communications},
  year    = {2022},
  doi     = {10.1186/s40478-022-01447-z},
  pmid    = {36180898},
  url     = {https://doi.org/10.1186/s40478-022-01447-z}
}

@article{dejanovic2022-37118504,
  author  = {Dejanovic, B. and Wu, T. and Tsai, M. C. and Graykowski, D. and Gandham, V. D. and Rose, C. M. and Bakalarski, C. E. and Ngu, H. and others},
  title   = {{Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse models}},
  journal = {Nature aging},
  year    = {2022},
  doi     = {10.1038/s43587-022-00281-1},
  pmid    = {37118504},
  url     = {https://doi.org/10.1038/s43587-022-00281-1}
}

@article{margeta2022-35977543,
  author  = {Margeta, M. A. and Yin, Z. and Madore, C. and Pitts, K. M. and Letcher, S. M. and Tang, J. and Jiang, S. and Gauthier, C. D. and others},
  title   = {{Apolipoprotein E4 impairs the response of neurodegenerative retinal microglia and prevents neuronal loss in glaucoma}},
  journal = {Immunity},
  year    = {2022},
  doi     = {10.1016/j.immuni.2022.07.014},
  pmid    = {35977543},
  url     = {https://doi.org/10.1016/j.immuni.2022.07.014}
}

@article{garciarevilla2022-35859075,
  author  = {García-Revilla, J. and Boza-Serrano, A. and Espinosa-Oliva, A. M. and Soto, M. S. and Deierborg, T. and Ruiz, R. and de Pablos, R. M. and Burguillos, M. A. and others},
  title   = {{Galectin-3, a rising star in modulating microglia activation under conditions of neurodegeneration}},
  journal = {Cell death \& disease},
  year    = {2022},
  doi     = {10.1038/s41419-022-05058-3},
  pmid    = {35859075},
  url     = {https://doi.org/10.1038/s41419-022-05058-3}
}

@article{zegarravaldivia2022-36636477,
  author  = {Zegarra-Valdivia, J. and Fernandez, A. M. and Martinez-Rachadell, L. and Herrero-Labrador, R. and Fernandes, J. and Torres Aleman, I.},
  title   = {{Insulin and insulin-like growth factor-I receptors in astrocytes exert different effects on behavior and Alzheimer´s-like pathology}},
  journal = {F1000Research},
  year    = {2022},
  doi     = {10.12688/f1000research.121901.3},
  pmid    = {36636477},
  url     = {https://doi.org/10.12688/f1000research.121901.3}
}

@article{xiong2022-35704147,
  author  = {Xiong, J. and Deng, I. and Kelliny, S. and Lin, L. and Bobrovskaya, L. and Zhou, X. F.},
  title   = {{Long term high fat diet induces metabolic disorders and aggravates behavioral disorders and cognitive deficits in MAPT P301L transgenic mice}},
  journal = {Metabolic brain disease},
  year    = {2022},
  doi     = {10.1007/s11011-022-01029-x},
  pmid    = {35704147},
  url     = {https://doi.org/10.1007/s11011-022-01029-x}
}

@article{liu2022-35712121,
  author  = {Liu, Z. and Gao, Z. and Li, B. and Li, J. and Ou, Y. and Yu, X. and Zhang, Z. and Liu, S. and others},
  title   = {{Lipid-associated macrophages in the tumor-adipose microenvironment facilitate breast cancer progression}},
  journal = {Oncoimmunology},
  year    = {2022},
  doi     = {10.1080/2162402x.2022.2085432},
  pmid    = {35712121},
  url     = {https://doi.org/10.1080/2162402x.2022.2085432}
}

@article{sanjay2022-35670898,
  author  = {Sanjay and Shin, J. H. and Park, M. and Lee, H. J.},
  title   = {{Cyanidin-3-O-Glucoside Regulates the M1/M2 Polarization of Microglia via PPARγ and Aβ42 Phagocytosis Through TREM2 in an Alzheimer's Disease Model}},
  journal = {Molecular neurobiology},
  year    = {2022},
  doi     = {10.1007/s12035-022-02873-9},
  pmid    = {35670898},
  url     = {https://doi.org/10.1007/s12035-022-02873-9}
}

@article{spurrier2022-35648810,
  author  = {Spurrier, J. and Nicholson, L. and Fang, X. T. and Stoner, A. J. and Toyonaga, T. and Holden, D. and Siegert, T. R. and Laird, W. and others},
  title   = {{Reversal of synapse loss in Alzheimer mouse models by targeting mGluR5 to prevent synaptic tagging by C1Q}},
  journal = {Science translational medicine},
  year    = {2022},
  doi     = {10.1126/scitranslmed.abi8593},
  pmid    = {35648810},
  url     = {https://doi.org/10.1126/scitranslmed.abi8593}
}

@article{endoumeda2022-35477277,
  author  = {Endo-Umeda, K. and Kim, E. and Thomas, D. G. and Liu, W. and Dou, H. and Yalcinkaya, M. and Abramowicz, S. and Xiao, T. and others},
  title   = {{Myeloid LXR (Liver X Receptor) Deficiency Induces Inflammatory Gene Expression in Foamy Macrophages and Accelerates Atherosclerosis}},
  journal = {Arteriosclerosis, thrombosis, and vascular biology},
  year    = {2022},
  doi     = {10.1161/atvbaha.122.317583},
  pmid    = {35477277},
  url     = {https://doi.org/10.1161/atvbaha.122.317583}
}

@article{simon2022-35473943,
  author  = {Simon, M. and Wang, M. X. and Ismail, O. and Braun, M. and Schindler, A. G. and Reemmer, J. and Wang, Z. and Haveliwala, M. A. and others},
  title   = {{Loss of perivascular aquaporin-4 localization impairs glymphatic exchange and promotes amyloid β plaque formation in mice}},
  journal = {Alzheimer's research \& therapy},
  year    = {2022},
  doi     = {10.1186/s13195-022-00999-5},
  pmid    = {35473943},
  url     = {https://doi.org/10.1186/s13195-022-00999-5}
}

@article{liu2022-35366241,
  author  = {Liu, H. and Jin, M. and Ji, M. and Zhang, W. and Liu, A. and Wang, T.},
  title   = {{Hypoxic pretreatment of adipose-derived stem cell exosomes improved cognition by delivery of circ-Epc1 and shifting microglial M1/M2 polarization in an Alzheimer's disease mice model}},
  journal = {Aging},
  year    = {2022},
  doi     = {10.18632/aging.203989},
  pmid    = {35366241},
  url     = {https://doi.org/10.18632/aging.203989}
}

@article{study2022-b8154517,
  title   = {{Retraction: High-Affinity Naloxone Binding to Filamin A Prevents Mu Opioid Receptor-Gs Coupling / Retraction: Naloxone's Pentapeptide Binding Site on Filamin A Blocks Mu Opioid Receptor-Gs Coupling (among five Wang-authored papers retracted)}},
  journal = {PLOS ONE},
  year    = {2022}
}

@article{brown2022-35197628,
  author  = {Brown, A. L. and Wilkins, O. G. and Keuss, M. J. and Kargbo-Hill, S. E. and Zanovello, M. and Lee, W. C. and Bampton, A. and Lee, F. C. Y. and others},
  title   = {{TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A}},
  journal = {Nature},
  year    = {2022},
  doi     = {10.1038/s41586-022-04436-3},
  pmid    = {35197628},
  url     = {https://doi.org/10.1038/s41586-022-04436-3}
}

@article{ma2022-35197626,
  author  = {Ma, X. R. and Prudencio, M. and Koike, Y. and Vatsavayai, S. C. and Kim, G. and Harbinski, F. and Briner, A. and Rodriguez, C. M. and others},
  title   = {{TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A}},
  journal = {Nature},
  year    = {2022},
  doi     = {10.1038/s41586-022-04424-7},
  pmid    = {35197626},
  url     = {https://doi.org/10.1038/s41586-022-04424-7}
}

@article{mann2022-35171651,
  author  = {Mann, C. N. and Devi, S. S. and Kersting, C. T. and Bleem, A. V. and Karch, C. M. and Holtzman, D. M. and Gallardo, G.},
  title   = {{Astrocytic α2-Na+/K+ ATPase inhibition suppresses astrocyte reactivity and reduces neurodegeneration in a tauopathy mouse model}},
  journal = {Science translational medicine},
  year    = {2022},
  doi     = {10.1126/scitranslmed.abm4107},
  pmid    = {35171651},
  url     = {https://doi.org/10.1126/scitranslmed.abm4107}
}

@article{markovinovic2022-35129196,
  author  = {Markovinovic, A. and Greig, J. and Martín-Guerrero, S. M. and Salam, S. and Paillusson, S.},
  title   = {{Endoplasmic reticulum-mitochondria signaling in neurons and neurodegenerative diseases}},
  journal = {Journal of cell science},
  year    = {2022},
  doi     = {10.1242/jcs.248534},
  pmid    = {35129196},
  url     = {https://doi.org/10.1242/jcs.248534}
}

@article{gruijsdasilva2022-35112738,
  author  = {Gruijs da Silva, L. A. and Simonetti, F. and Hutten, S. and Riemenschneider, H. and Sternburg, E. L. and Pietrek, L. M. and Gebel, J. and Dötsch, V. and others},
  title   = {{Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation}},
  journal = {The EMBO journal},
  year    = {2022},
  doi     = {10.15252/embj.2021108443},
  pmid    = {35112738},
  url     = {https://doi.org/10.15252/embj.2021108443}
}

@article{dodge2022-35105352,
  author  = {Dodge, J. C. and Tamsett, T. J. and Treleaven, C. M. and Taksir, T. V. and Piepenhagen, P. and Sardi, S. P. and Cheng, S. H. and Shihabuddin, L. S.},
  title   = {{Glucosylceramide synthase inhibition reduces ganglioside GM3 accumulation, alleviates amyloid neuropathology, and stabilizes remote contextual memory in a mouse model of Alzheimer's disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2022},
  doi     = {10.1186/s13195-022-00966-0},
  pmid    = {35105352},
  url     = {https://doi.org/10.1186/s13195-022-00966-0}
}

@article{fu2022-35091012,
  author  = {Fu, C. and Wu, Y. and Liu, S. and Luo, C. and Lu, Y. and Liu, M. and Wang, L. and Zhang, Y. and others},
  title   = {{Rehmannioside A improves cognitive impairment and alleviates ferroptosis via activating PI3K/AKT/Nrf2 and SLC7A11/GPX4 signaling pathway after ischemia}},
  journal = {Journal of ethnopharmacology},
  year    = {2022},
  doi     = {10.1016/j.jep.2022.115021},
  pmid    = {35091012},
  url     = {https://doi.org/10.1016/j.jep.2022.115021}
}

@article{korben2022-35075293,
  author  = {Korben, V. A. and Lyashchenko, A. K. and Blanco-Redondo, B. and Jafar-Nejad, P. and Shneider, N. A.},
  title   = {{Antisense oligonucleotide silencing of FUS expression as a therapeutic approach in amyotrophic lateral sclerosis}},
  journal = {Nature medicine},
  year    = {2022},
  doi     = {10.1038/s41591-021-01615-z},
  pmid    = {35075293},
  url     = {https://doi.org/10.1038/s41591-021-01615-z}
}

@article{saha2021-35126058,
  author  = {Saha, S. and Buttari, B. and Profumo, E. and Tucci, P. and Saso, L.},
  title   = {{A Perspective on Nrf2 Signaling Pathway for Neuroinflammation: A Potential Therapeutic Target in Alzheimer's and Parkinson's Diseases}},
  journal = {Frontiers in cellular neuroscience},
  year    = {2021},
  doi     = {10.3389/fncel.2021.787258},
  pmid    = {35126058},
  url     = {https://doi.org/10.3389/fncel.2021.787258}
}

@article{rhinn2022-35039149,
  author  = {Rhinn, H. and Tatton, N. and McCaughey, S. and Kurnellas, M. and Rosenthal, A.},
  title   = {{Progranulin as a therapeutic target in neurodegenerative diseases}},
  journal = {Trends in pharmacological sciences},
  year    = {2022},
  doi     = {10.1016/j.tips.2021.11.015},
  pmid    = {35039149},
  url     = {https://doi.org/10.1016/j.tips.2021.11.015}
}

@article{song2022-35017668,
  author  = {Song, S. and Yu, L. and Hasan, M. N. and Paruchuri, S. S. and Mullett, S. J. and Sullivan, M. L. G. and Fiesler, V. M. and Young, C. B. and others},
  title   = {{Elevated microglial oxidative phosphorylation and phagocytosis stimulate post-stroke brain remodeling and cognitive function recovery in mice}},
  journal = {Communications biology},
  year    = {2022},
  doi     = {10.1038/s42003-021-02984-4},
  pmid    = {35017668},
  url     = {https://doi.org/10.1038/s42003-021-02984-4}
}

@article{brosseron2022-34995486,
  author  = {Brosseron, F. and Maass, A. and Kleineidam, L. and Ravichandran, K. A. and González, P. G. and McManus, R. M. and Ising, C. and Santarelli, F. and others},
  title   = {{Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer's disease}},
  journal = {Neuron},
  year    = {2022},
  doi     = {10.1016/j.neuron.2021.12.016},
  pmid    = {34995486},
  url     = {https://doi.org/10.1016/j.neuron.2021.12.016}
}

@article{you2022-35029059,
  author  = {You, Y. and Muraoka, S. and Jedrychowski, M. P. and Hu, J. and McQuade, A. K. and Young-Pearse, T. and Aslebagh, R. and Shaffer, S. A. and others},
  title   = {{Human neural cell type-specific extracellular vesicle proteome defines disease-related molecules associated with activated astrocytes in Alzheimer's disease brain}},
  journal = {Journal of extracellular vesicles},
  year    = {2022},
  doi     = {10.1002/jev2.12183},
  pmid    = {35029059},
  url     = {https://doi.org/10.1002/jev2.12183}
}

@article{deleeuw2022-34919811,
  author  = {de Leeuw, S. M. and Kirschner, A. W. T. and Lindner, K. and Rust, R. and Budny, V. and Wolski, W. E. and Gavin, A. C. and Nitsch, R. M. and others},
  title   = {{APOE2, E3, and E4 differentially modulate cellular homeostasis, cholesterol metabolism, and inflammatory response in isogenic iPSC-derived astrocytes}},
  journal = {Stem cell reports},
  year    = {2022},
  doi     = {10.1016/j.stemcr.2021.11.007},
  pmid    = {34919811},
  url     = {https://doi.org/10.1016/j.stemcr.2021.11.007}
}

@article{eratne2022-35179048,
  author  = {Eratne, D. and Janelidze, S. and Malpas, C. B. and Loi, S. and Walterfang, M. and Merritt, A. and Diouf, I. and Blennow, K. and others},
  title   = {{Plasma neurofilament light chain protein is not increased in treatment-resistant schizophrenia and first-degree relatives}},
  journal = {The Australian and New Zealand journal of psychiatry},
  year    = {2022},
  doi     = {10.1177/00048674211058684},
  pmid    = {35179048},
  url     = {https://doi.org/10.1177/00048674211058684}
}

@article{soares2021-34831271,
  author  = {Soares, L. C. and Al-Dalahmah, O. and Hillis, J. and Young, C. C. and Asbed, I. and Sakaguchi, M. and O'Neill, E. and Szele, F. G.},
  title   = {{Novel Galectin-3 Roles in Neurogenesis, Inflammation and Neurological Diseases}},
  journal = {Cells},
  year    = {2021},
  doi     = {10.3390/cells10113047},
  pmid    = {34831271},
  url     = {https://doi.org/10.3390/cells10113047}
}

@article{barker2021-34731014,
  author  = {Barker, S. J. and Raju, R. M. and Milman, N. E. P. and Wang, J. and Davila-Velderrain, J. and Gunter-Rahman, F. and Parro, C. C. and Bozzelli, P. L. and others},
  title   = {{MEF2 is a key regulator of cognitive potential and confers resilience to neurodegeneration}},
  journal = {Science translational medicine},
  year    = {2021},
  doi     = {10.1126/scitranslmed.abd7695},
  pmid    = {34731014},
  url     = {https://doi.org/10.1126/scitranslmed.abd7695}
}

@article{xiang2021-34644146,
  author  = {Xiang, X. and Wind, K. and Wiedemann, T. and Blume, T. and Shi, Y. and Briel, N. and Beyer, L. and Biechele, G. and others},
  title   = {{Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases}},
  journal = {Science translational medicine},
  year    = {2021},
  doi     = {10.1126/scitranslmed.abe5640},
  pmid    = {34644146},
  url     = {https://doi.org/10.1126/scitranslmed.abe5640}
}

@article{malik2021-34626176,
  author  = {Malik, R. and Beaufort, N. and Frerich, S. and Gesierich, B. and Georgakis, M. K. and Rannikmäe, K. and Ferguson, A. C. and Haffner, C. and others},
  title   = {{Whole-exome sequencing reveals a role of HTRA1 and EGFL8 in brain white matter hyperintensities}},
  journal = {Brain : a journal of neurology},
  year    = {2021},
  doi     = {10.1093/brain/awab253},
  pmid    = {34626176},
  url     = {https://doi.org/10.1093/brain/awab253}
}

@article{zhao2021-34593014,
  author  = {Zhao, F. and Xu, Y. and Gao, S. and Qin, L. and Austria, Q. and Siedlak, S. L. and Pajdzik, K. and Dai, Q. and others},
  title   = {{METTL3-dependent RNA m6A dysregulation contributes to neurodegeneration in Alzheimer's disease through aberrant cell cycle events}},
  journal = {Molecular neurodegeneration},
  year    = {2021},
  doi     = {10.1186/s13024-021-00484-x},
  pmid    = {34593014},
  url     = {https://doi.org/10.1186/s13024-021-00484-x}
}

@article{zhao2021-34530866,
  author  = {Zhao, Y. and Zhang, J. and Zheng, Y. and Zhang, Y. and Zhang, X. J. and Wang, H. and Du, Y. and Guan, J. and others},
  title   = {{NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway}},
  journal = {Journal of neuroinflammation},
  year    = {2021},
  doi     = {10.1186/s12974-021-02250-8},
  pmid    = {34530866},
  url     = {https://doi.org/10.1186/s12974-021-02250-8}
}

@article{logan2021-34450028,
  author  = {Logan, T. and Simon, M. J. and Rana, A. and Cherf, G. M. and Srivastava, A. and Davis, S. S. and Low, R. L. Y. and Chiu, C. L. and others},
  title   = {{Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic}},
  journal = {Cell},
  year    = {2021},
  doi     = {10.1016/j.cell.2021.08.002},
  pmid    = {34450028},
  url     = {https://doi.org/10.1016/j.cell.2021.08.002}
}

@article{miglis2021-34302789,
  author  = {Miglis, M. G. and Adler, C. H. and Antelmi, E. and Arnaldi, D. and Baldelli, L. and Boeve, B. F. and Cesari, M. and Dall'Antonia, I. and others},
  title   = {{Biomarkers of conversion to α-synucleinopathy in isolated rapid-eye-movement sleep behaviour disorder}},
  journal = {The Lancet. Neurology},
  year    = {2021},
  doi     = {10.1016/s1474-4422(21)00176-9},
  pmid    = {34302789},
  url     = {https://doi.org/10.1016/s1474-4422(21)00176-9}
}

@article{picard2021-34343616,
  author  = {Picard, K. and Bisht, K. and Poggini, S. and Garofalo, S. and Golia, M. T. and Basilico, B. and Abdallah, F. and Ciano Albanese, N. and others},
  title   = {{Microglial-glucocorticoid receptor depletion alters the response of hippocampal microglia and neurons in a chronic unpredictable mild stress paradigm in female mice}},
  journal = {Brain, behavior, and immunity},
  year    = {2021},
  doi     = {10.1016/j.bbi.2021.07.022},
  pmid    = {34343616},
  url     = {https://doi.org/10.1016/j.bbi.2021.07.022}
}

@article{tong2022-34313551,
  author  = {Tong, B. C. and Wu, A. J. and Huang, A. S. and Dong, R. and Malampati, S. and Iyaswamy, A. and Krishnamoorthi, S. and Sreenivasmurthy, S. G. and others},
  title   = {{Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease}},
  journal = {Autophagy},
  year    = {2022},
  doi     = {10.1080/15548627.2021.1945220},
  pmid    = {34313551},
  url     = {https://doi.org/10.1080/15548627.2021.1945220}
}

@article{gaikwad2021-34289368,
  author  = {Gaikwad, S. and Puangmalai, N. and Bittar, A. and Montalbano, M. and Garcia, S. and McAllen, S. and Bhatt, N. and Sonawane, M. and others},
  title   = {{Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer's disease and frontotemporal dementia}},
  journal = {Cell reports},
  year    = {2021},
  doi     = {10.1016/j.celrep.2021.109419},
  pmid    = {34289368},
  url     = {https://doi.org/10.1016/j.celrep.2021.109419}
}

@article{mandour2021-34170456,
  author  = {Mandour, D. A. and Bendary, M. A. and Alsemeh, A. E.},
  title   = {{Histological and imunohistochemical alterations of hippocampus and prefrontal cortex in a rat model of Alzheimer like-disease with a preferential role of the flavonoid "hesperidin"}},
  journal = {Journal of molecular histology},
  year    = {2021},
  doi     = {10.1007/s10735-021-09998-6},
  pmid    = {34170456},
  url     = {https://doi.org/10.1007/s10735-021-09998-6}
}

@article{macdonald2021-34143756,
  author  = {MacDonald, L. and Alivernini, S. and Tolusso, B. and Elmesmari, A. and Somma, D. and Perniola, S. and Paglionico, A. and Petricca, L. and others},
  title   = {{COVID-19 and RA share an SPP1 myeloid pathway that drives PD-L1+ neutrophils and CD14+ monocytes}},
  journal = {JCI insight},
  year    = {2021},
  doi     = {10.1172/jci.insight.147413},
  pmid    = {34143756},
  url     = {https://doi.org/10.1172/jci.insight.147413}
}

@article{ardighieri2021-34220848,
  author  = {Ardighieri, L. and Missale, F. and Bugatti, M. and Gatta, L. B. and Pezzali, I. and Monti, M. and Gottardi, S. and Zanotti, L. and others},
  title   = {{Infiltration by CXCL10 Secreting Macrophages Is Associated With Antitumor Immunity and Response to Therapy in Ovarian Cancer Subtypes}},
  journal = {Frontiers in immunology},
  year    = {2021},
  doi     = {10.3389/fimmu.2021.690201},
  pmid    = {34220848},
  url     = {https://doi.org/10.3389/fimmu.2021.690201}
}

@article{lall2021-34133945,
  author  = {Lall, D. and Lorenzini, I. and Mota, T. A. and Bell, S. and Mahan, T. E. and Ulrich, J. D. and Davtyan, H. and Rexach, J. E. and others},
  title   = {{C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation}},
  journal = {Neuron},
  year    = {2021},
  doi     = {10.1016/j.neuron.2021.05.020},
  pmid    = {34133945},
  url     = {https://doi.org/10.1016/j.neuron.2021.05.020}
}

@article{desale2021-35006431,
  author  = {Desale, S. E. and Chidambaram, H. and Chinnathambi, S.},
  title   = {{G-protein coupled receptor, PI3K and Rho signaling pathways regulate the cascades of Tau and amyloid-β in Alzheimer's disease}},
  journal = {Molecular biomedicine},
  year    = {2021},
  doi     = {10.1186/s43556-021-00036-1},
  pmid    = {35006431},
  url     = {https://doi.org/10.1186/s43556-021-00036-1}
}

@article{gwon2021-34739333,
  author  = {Gwon, Y. and Maxwell, B. A. and Kolaitis, R. M. and Zhang, P. and Kim, H. J. and Taylor, J. P.},
  title   = {{Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner}},
  journal = {Science (New York, N.Y.)},
  year    = {2021},
  doi     = {10.1126/science.abf6548},
  pmid    = {34739333},
  url     = {https://doi.org/10.1126/science.abf6548}
}

@article{abdelfatah2021-34052296,
  author  = {Abd El-Fatah, I. M. and Abdelrazek, H. M. A. and Ibrahim, S. M. and Abdallah, D. M. and El-Abhar, H. S.},
  title   = {{Dimethyl fumarate abridged tauo-/amyloidopathy in a D-Galactose/ovariectomy-induced Alzheimer's-like disease: Modulation of AMPK/SIRT-1, AKT/CREB/BDNF, AKT/GSK-3β, adiponectin/Adipo1R, and NF-κB/IL-1β/ROS trajectories}},
  journal = {Neurochemistry international},
  year    = {2021},
  doi     = {10.1016/j.neuint.2021.105082},
  pmid    = {34052296},
  url     = {https://doi.org/10.1016/j.neuint.2021.105082}
}

@article{damesquita2021-33911285,
  author  = {Da Mesquita, S. and Papadopoulos, Z. and Dykstra, T. and Brase, L. and Farias, F. G. and Wall, M. and Jiang, H. and Kodira, C. D. and others},
  title   = {{Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy}},
  journal = {Nature},
  year    = {2021},
  doi     = {10.1038/s41586-021-03489-0},
  pmid    = {33911285},
  url     = {https://doi.org/10.1038/s41586-021-03489-0}
}

@article{park2021-33902708,
  author  = {Park, J. S. and Kam, T. I. and Lee, S. and Park, H. and Oh, Y. and Kwon, S. H. and Song, J. J. and Kim, D. and others},
  title   = {{Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer's disease}},
  journal = {Acta neuropathologica communications},
  year    = {2021},
  doi     = {10.1186/s40478-021-01180-z},
  pmid    = {33902708},
  url     = {https://doi.org/10.1186/s40478-021-01180-z}
}

@article{saviano2021-33845375,
  author  = {Saviano, A. and Casillo, G. M. and Raucci, F. and Pernice, A. and Santarcangelo, C. and Piccolo, M. and Ferraro, M. G. and Ciccone, M. and others},
  title   = {{Supplementation with ribonucleotide-based ingredient (Ribodiet®) lessens oxidative stress, brain inflammation, and amyloid pathology in a murine model of Alzheimer}},
  journal = {Biomedicine \& pharmacotherapy = Biomedecine \& pharmacotherapie},
  year    = {2021},
  doi     = {10.1016/j.biopha.2021.111579},
  pmid    = {33845375},
  url     = {https://doi.org/10.1016/j.biopha.2021.111579}
}

@article{kemp2021-33782087,
  author  = {Kemp, S. B. and Steele, N. G. and Carpenter, E. S. and Donahue, K. L. and Bushnell, G. G. and Morris, A. H. and The, S. and Orbach, S. M. and others},
  title   = {{Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages}},
  journal = {Life science alliance},
  year    = {2021},
  doi     = {10.26508/lsa.202000935},
  pmid    = {33782087},
  url     = {https://doi.org/10.26508/lsa.202000935}
}

@article{chen2021-33729626,
  author  = {Chen, M. J. and Ramesha, S. and Weinstock, L. D. and Gao, T. and Ping, L. and Xiao, H. and Dammer, E. B. and Duong, D. D. and others},
  title   = {{Extracellular signal-regulated kinase regulates microglial immune responses in Alzheimer's disease}},
  journal = {Journal of neuroscience research},
  year    = {2021},
  doi     = {10.1002/jnr.24829},
  pmid    = {33729626},
  url     = {https://doi.org/10.1002/jnr.24829}
}

@article{tziortzouda2021-33654312,
  author  = {Tziortzouda, P. and Van Den Bosch, L. and Hirth, F.},
  title   = {{Triad of TDP43 control in neurodegeneration: autoregulation, localization and aggregation}},
  journal = {Nature reviews. Neuroscience},
  year    = {2021},
  doi     = {10.1038/s41583-021-00431-1},
  pmid    = {33654312},
  url     = {https://doi.org/10.1038/s41583-021-00431-1}
}

@article{iranzo2021-33609478,
  author  = {Iranzo, A. and Fairfoul, G. and Ayudhaya, A. C. N. and Serradell, M. and Gelpi, E. and Vilaseca, I. and Sanchez-Valle, R. and Gaig, C. and others},
  title   = {{Detection of α-synuclein in CSF by RT-QuIC in patients with isolated rapid-eye-movement sleep behaviour disorder: a longitudinal observational study}},
  journal = {The Lancet. Neurology},
  year    = {2021},
  doi     = {10.1016/s1474-4422(20)30449-x},
  pmid    = {33609478},
  url     = {https://doi.org/10.1016/s1474-4422(20)30449-x}
}

@article{crews2021-33611821,
  author  = {Crews, F. T. and Zou, J. and Coleman, L. G.},
  title   = {{Extracellular microvesicles promote microglia-mediated pro-inflammatory responses to ethanol}},
  journal = {Journal of neuroscience research},
  year    = {2021},
  doi     = {10.1002/jnr.24813},
  pmid    = {33611821},
  url     = {https://doi.org/10.1002/jnr.24813}
}

@article{gonzalezmolina2021-33679370,
  author  = {González-Molina, L. A. and Villar-Vesga, J. and Henao-Restrepo, J. and Villegas, A. and Lopera, F. and Cardona-Gómez, G. P. and Posada-Duque, R.},
  title   = {{Extracellular Vesicles From 3xTg-AD Mouse and Alzheimer's Disease Patient Astrocytes Impair Neuroglial and Vascular Components}},
  journal = {Frontiers in aging neuroscience},
  year    = {2021},
  doi     = {10.3389/fnagi.2021.593927},
  pmid    = {33679370},
  url     = {https://doi.org/10.3389/fnagi.2021.593927}
}

@article{boschqueralt2021-33619376,
  author  = {Bosch-Queralt, M. and Cantuti-Castelvetri, L. and Damkou, A. and Schifferer, M. and Schlepckow, K. and Alexopoulos, I. and Lütjohann, D. and Klose, C. and others},
  title   = {{Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination}},
  journal = {Nature metabolism},
  year    = {2021},
  doi     = {10.1038/s42255-021-00341-7},
  pmid    = {33619376},
  url     = {https://doi.org/10.1038/s42255-021-00341-7}
}

@article{dong2021-33603230,
  author  = {Dong, Y. and D'Mello, C. and Pinsky, W. and Lozinski, B. M. and Kaushik, D. K. and Ghorbani, S. and Moezzi, D. and Brown, D. and others},
  title   = {{Oxidized phosphatidylcholines found in multiple sclerosis lesions mediate neurodegeneration and are neutralized by microglia}},
  journal = {Nature neuroscience},
  year    = {2021},
  doi     = {10.1038/s41593-021-00801-z},
  pmid    = {33603230},
  url     = {https://doi.org/10.1038/s41593-021-00801-z}
}

@article{zheng2021-33548579,
  author  = {Zheng, Y. and Zhang, J. and Zhao, Y. and Zhang, Y. and Zhang, X. and Guan, J. and Liu, Y. and Fu, J.},
  title   = {{Curcumin protects against cognitive impairments in a rat model of chronic cerebral hypoperfusion combined with diabetes mellitus by suppressing neuroinflammation, apoptosis, and pyroptosis}},
  journal = {International immunopharmacology},
  year    = {2021},
  doi     = {10.1016/j.intimp.2021.107422},
  pmid    = {33548579},
  url     = {https://doi.org/10.1016/j.intimp.2021.107422}
}

@article{trudler2021-33483428,
  author  = {Trudler, D. and Sanz-Blasco, S. and Eisele, Y. S. and Ghatak, S. and Bodhinathan, K. and Akhtar, M. W. and Lynch, W. P. and Piña-Crespo, J. C. and others},
  title   = {{α-Synuclein Oligomers Induce Glutamate Release from Astrocytes and Excessive Extrasynaptic NMDAR Activity in Neurons, Thus Contributing to Synapse Loss}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2021},
  doi     = {10.1523/jneurosci.1871-20.2020},
  pmid    = {33483428},
  url     = {https://doi.org/10.1523/jneurosci.1871-20.2020}
}

@article{maornof2021-33482083,
  author  = {Maor-Nof, M. and Shipony, Z. and Lopez-Gonzalez, R. and Nakayama, L. and Zhang, Y. J. and Couthouis, J. and Blum, J. A. and Castruita, P. A. and others},
  title   = {{p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)}},
  journal = {Cell},
  year    = {2021},
  doi     = {10.1016/j.cell.2020.12.025},
  pmid    = {33482083},
  url     = {https://doi.org/10.1016/j.cell.2020.12.025}
}

@article{wani2021-33404280,
  author  = {Wani, A. and Al Rihani, S. B. and Sharma, A. and Weadick, B. and Govindarajan, R. and Khan, S. U. and Sharma, P. R. and Dogra, A. and others},
  title   = {{Crocetin promotes clearance of amyloid-β by inducing autophagy via the STK11/LKB1-mediated AMPK pathway}},
  journal = {Autophagy},
  year    = {2021},
  doi     = {10.1080/15548627.2021.1872187},
  pmid    = {33404280},
  url     = {https://doi.org/10.1080/15548627.2021.1872187}
}

@article{daemen2021-33440159,
  author  = {Daemen, S. and Gainullina, A. and Kalugotla, G. and He, L. and Chan, M. M. and Beals, J. W. and Liss, K. H. and Klein, S. and others},
  title   = {{Dynamic Shifts in the Composition of Resident and Recruited Macrophages Influence Tissue Remodeling in NASH}},
  journal = {Cell reports},
  year    = {2021},
  doi     = {10.1016/j.celrep.2020.108626},
  pmid    = {33440159},
  url     = {https://doi.org/10.1016/j.celrep.2020.108626}
}

@article{mengr2021-34551697,
  author  = {Mengr, A. and Hrubá, L. and Exnerová, A. and Holubová, M. and Popelová, A. and Železná, B. and Kuneš, J. and Maletínská, L.},
  title   = {{Palmitoylated Prolactin-releasing Peptide Reduced Aβ Plaques and Microgliosis in the Cerebellum: APP/PS1 Mice Study}},
  journal = {Current Alzheimer research},
  year    = {2021},
  doi     = {10.2174/1567205018666210922110652},
  pmid    = {34551697},
  url     = {https://doi.org/10.2174/1567205018666210922110652}
}

@article{biechele2021-33385560,
  author  = {Biechele, G. and Wind, K. and Blume, T. and Sacher, C. and Beyer, L. and Eckenweber, F. and Franzmeier, N. and Ewers, M. and others},
  title   = {{Microglial activation in the right amygdala-entorhinal-hippocampal complex is associated with preserved spatial learning in AppNL-G-F mice}},
  journal = {NeuroImage},
  year    = {2021},
  doi     = {10.1016/j.neuroimage.2020.117707},
  pmid    = {33385560},
  url     = {https://doi.org/10.1016/j.neuroimage.2020.117707}
}

@article{noori2021-33347974,
  author  = {Noori, A. and Mezlini, A. M. and Hyman, B. T. and Serrano-Pozo, A. and Das, S.},
  title   = {{Systematic review and meta-analysis of human transcriptomics reveals neuroinflammation, deficient energy metabolism, and proteostasis failure across neurodegeneration}},
  journal = {Neurobiology of disease},
  year    = {2021},
  doi     = {10.1016/j.nbd.2020.105225},
  pmid    = {33347974},
  url     = {https://doi.org/10.1016/j.nbd.2020.105225}
}

@article{lananna2020-33328329,
  author  = {Lananna, B. V. and McKee, C. A. and King, M. W. and Del-Aguila, J. L. and Dimitry, J. M. and Farias, F. H. G. and Nadarajah, C. J. and Xiong, D. D. and others},
  title   = {{Chi3l1/YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer's disease pathogenesis}},
  journal = {Science translational medicine},
  year    = {2020},
  doi     = {10.1126/scitranslmed.aax3519},
  pmid    = {33328329},
  url     = {https://doi.org/10.1126/scitranslmed.aax3519}
}

@article{mota2020-33246465,
  author  = {Mota, M. and Porrini, V. and Parrella, E. and Benarese, M. and Bellucci, A. and Rhein, S. and Schwaninger, M. and Pizzi, M.},
  title   = {{Neuroprotective epi-drugs quench the inflammatory response and microglial/macrophage activation in a mouse model of permanent brain ischemia}},
  journal = {Journal of neuroinflammation},
  year    = {2020},
  doi     = {10.1186/s12974-020-02028-4},
  pmid    = {33246465},
  url     = {https://doi.org/10.1186/s12974-020-02028-4}
}

@article{lowry2020-33161065,
  author  = {Lowry, JR. and Marshall, N. and Wenzel, T. J. and Murray, T. E. and Klegeris, A.},
  title   = {{The dietary fatty acids α-linolenic acid (ALA) and linoleic acid (LA) selectively inhibit microglial nitric oxide production}},
  journal = {Molecular and cellular neurosciences},
  year    = {2020},
  doi     = {10.1016/j.mcn.2020.103569},
  pmid    = {33161065},
  url     = {https://doi.org/10.1016/j.mcn.2020.103569}
}

@article{ali2021-33159979,
  author  = {Ali, A. and Shah, S. A. and Zaman, N. and Uddin, M. N. and Khan, W. and Riaz, M. and Kamil, A.},
  title   = {{Vitamin D exerts neuroprotection via SIRT1/nrf-2/ NF-kB signaling pathways against D-galactose-induced memory impairment in adult mice}},
  journal = {Neurochemistry international},
  year    = {2021},
  doi     = {10.1016/j.neuint.2020.104893},
  pmid    = {33159979},
  url     = {https://doi.org/10.1016/j.neuint.2020.104893}
}

@article{prudencio2020-32790644,
  author  = {Prudencio, M. and Humphrey, J. and Pickles, S. and Brown, A. L. and Hill, S. E. and Kachergus, J. M. and Shi, J. and Heckman, M. G. and others},
  title   = {{Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia}},
  journal = {The Journal of clinical investigation},
  year    = {2020},
  doi     = {10.1172/jci139741},
  pmid    = {32790644},
  url     = {https://doi.org/10.1172/jci139741}
}

@article{wang2020-33081801,
  author  = {Wang, Y. and Shi, Y. and Huang, Y. and Liu, W. and Cai, G. and Huang, S. and Zeng, Y. and Ren, S. and others},
  title   = {{Resveratrol mediates mechanical allodynia through modulating inflammatory response via the TREM2-autophagy axis in SNI rat model}},
  journal = {Journal of neuroinflammation},
  year    = {2020},
  doi     = {10.1186/s12974-020-01991-2},
  pmid    = {33081801},
  url     = {https://doi.org/10.1186/s12974-020-01991-2}
}

@article{jo2020-33051572,
  author  = {Jo, M. and Lee, S. and Jeon, Y. M. and Kim, S. and Kwon, Y. and Kim, H. J.},
  title   = {{The role of TDP-43 propagation in neurodegenerative diseases: integrating insights from clinical and experimental studies}},
  journal = {Experimental \& molecular medicine},
  year    = {2020},
  doi     = {10.1038/s12276-020-00513-7},
  pmid    = {33051572},
  url     = {https://doi.org/10.1038/s12276-020-00513-7}
}

@article{buzhdygan2020-33053430,
  author  = {Buzhdygan, T. P. and DeOre, B. J. and Baldwin-Leclair, A. and Bullock, T. A. and McGary, H. M. and Khan, J. A. and Razmpour, R. and Hale, J. F. and others},
  title   = {{The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood-brain barrier}},
  journal = {Neurobiology of disease},
  year    = {2020},
  doi     = {10.1016/j.nbd.2020.105131},
  pmid    = {33053430},
  url     = {https://doi.org/10.1016/j.nbd.2020.105131}
}

@article{visioli2022-33023416,
  author  = {Visioli, F. and Rodríguez-Pérez, M. and Ó, Gómez-Torres and Pintado-Losa, C. and Burgos-Ramos, E.},
  title   = {{Hydroxytyrosol improves mitochondrial energetics of a cellular model of Alzheimer's disease}},
  journal = {Nutritional neuroscience},
  year    = {2022},
  doi     = {10.1080/1028415x.2020.1829344},
  pmid    = {33023416},
  url     = {https://doi.org/10.1080/1028415x.2020.1829344}
}

@article{huang2020-33028409,
  author  = {Huang, M. and Modeste, E. and Dammer, E. and Merino, P. and Taylor, G. and Duong, D. M. and Deng, Q. and Holler, C. J. and others},
  title   = {{Network analysis of the progranulin-deficient mouse brain proteome reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations}},
  journal = {Acta neuropathologica communications},
  year    = {2020},
  doi     = {10.1186/s40478-020-01037-x},
  pmid    = {33028409},
  url     = {https://doi.org/10.1186/s40478-020-01037-x}
}

@article{kim2020-33008094,
  author  = {Kim, R. E. and Shin, C. Y. and Han, S. H. and Kwon, K. J.},
  title   = {{Astaxanthin Suppresses PM2.5-Induced Neuroinflammation by Regulating Akt Phosphorylation in BV-2 Microglial Cells}},
  journal = {International journal of molecular sciences},
  year    = {2020},
  doi     = {10.3390/ijms21197227},
  pmid    = {33008094},
  url     = {https://doi.org/10.3390/ijms21197227}
}

@article{zhao2020-32964663,
  author  = {Zhao, Y. and Zeng, C. Y. and Li, X. H. and Yang, T. T. and Kuang, X. and Du, JR.},
  title   = {{Klotho overexpression improves amyloid-β clearance and cognition in the APP/PS1 mouse model of Alzheimer's disease}},
  journal = {Aging cell},
  year    = {2020},
  doi     = {10.1111/acel.13239},
  pmid    = {32964663},
  url     = {https://doi.org/10.1111/acel.13239}
}

@article{yang2020-32963694,
  author  = {Yang, W. and Liu, Y. and Xu, Q. Q. and Xian, Y. F. and Lin, Z. X.},
  title   = {{Sulforaphene Ameliorates Neuroinflammation and Hyperphosphorylated Tau Protein via Regulating the PI3K/Akt/GSK-3β Pathway in Experimental Models of Alzheimer's Disease}},
  journal = {Oxidative medicine and cellular longevity},
  year    = {2020},
  doi     = {10.1155/2020/4754195},
  pmid    = {32963694},
  url     = {https://doi.org/10.1155/2020/4754195}
}

@article{bordeleau2020-32891154,
  author  = {Bordeleau, M. and Lacabanne, C. and Fernández de Cossío, L. and Vernoux, N. and Savage, J. C. and González-Ibáñez, F. and MÈ, Tremblay},
  title   = {{Microglial and peripheral immune priming is partially sexually dimorphic in adolescent mouse offspring exposed to maternal high-fat diet}},
  journal = {Journal of neuroinflammation},
  year    = {2020},
  doi     = {10.1186/s12974-020-01914-1},
  pmid    = {32891154},
  url     = {https://doi.org/10.1186/s12974-020-01914-1}
}

@article{zhao2020-32887883,
  author  = {Zhao, L. and Li, Z. and Vong, J. S. L. and Chen, X. and Lai, H. M. and Yan, L. Y. C. and Huang, J. and Sy, S. K. H. and others},
  title   = {{Pharmacologically reversible zonation-dependent endothelial cell transcriptomic changes with neurodegenerative disease associations in the aged brain}},
  journal = {Nature communications},
  year    = {2020},
  doi     = {10.1038/s41467-020-18249-3},
  pmid    = {32887883},
  url     = {https://doi.org/10.1038/s41467-020-18249-3}
}

@article{hur2020-32879487,
  author  = {Hur, J. Y. and Frost, G. R. and Wu, X. and Crump, C. and Pan, S. J. and Wong, E. and Barros, M. and Li, T. and others},
  title   = {{The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer's disease}},
  journal = {Nature},
  year    = {2020},
  doi     = {10.1038/s41586-020-2681-2},
  pmid    = {32879487},
  url     = {https://doi.org/10.1038/s41586-020-2681-2}
}

@article{sheikh2020-33832896,
  author  = {Sheikh, H. K. and Arshad, T. and Mohammad, Z. S. and Moussa, I. K. and Usman, R. and Hasan, M. M.},
  title   = {{Derivatives of diisopropyl phenoxyphosphate with controlled reactivity for enhancement of Acetylcholine (ACh) neurotransmitter}},
  journal = {Pakistan journal of pharmaceutical sciences},
  year    = {2020},
  pmid    = {33832896}
}

@article{cook2020-32878979,
  author  = {Cook, C. N. and Wu, Y. and Odeh, H. M. and Gendron, T. F. and Jansen-West, K. and Del Rosso, G. and Yue, M. and Jiang, P. and others},
  title   = {{C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy}},
  journal = {Science translational medicine},
  year    = {2020},
  doi     = {10.1126/scitranslmed.abb3774},
  pmid    = {32878979},
  url     = {https://doi.org/10.1126/scitranslmed.abb3774}
}

@article{wei2020-32854771,
  author  = {Wei, W. and Wang, Y. and Liu, Y. and Dai, C. L. and Tung, Y. C. and Liu, F. and Iqbal, K.},
  title   = {{Prenatal to early postnatal neurotrophic treatment prevents Alzheimer-like behavior and pathology in mice}},
  journal = {Alzheimer's research \& therapy},
  year    = {2020},
  doi     = {10.1186/s13195-020-00666-7},
  pmid    = {32854771},
  url     = {https://doi.org/10.1186/s13195-020-00666-7}
}

@article{ruan2020-32811520,
  author  = {Ruan, Z. and Delpech, J. C. and Venkatesan Kalavai, S. and Van Enoo, A. A. and Hu, J. and Ikezu, S. and Ikezu, T.},
  title   = {{P2RX7 inhibitor suppresses exosome secretion and disease phenotype in P301S tau transgenic mice}},
  journal = {Molecular neurodegeneration},
  year    = {2020},
  doi     = {10.1186/s13024-020-00396-2},
  pmid    = {32811520},
  url     = {https://doi.org/10.1186/s13024-020-00396-2}
}

@article{scotthewitt2020-32657463,
  author  = {Scott-Hewitt, N. and Perrucci, F. and Morini, R. and Erreni, M. and Mahoney, M. and Witkowska, A. and Carey, A. and Faggiani, E. and others},
  title   = {{Local externalization of phosphatidylserine mediates developmental synaptic pruning by microglia}},
  journal = {The EMBO journal},
  year    = {2020},
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@article{hannan2020-32714148,
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  title   = {{Neuroprotection Against Oxidative Stress: Phytochemicals Targeting TrkB Signaling and the Nrf2-ARE Antioxidant System}},
  journal = {Frontiers in molecular neuroscience},
  year    = {2020},
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  pmid    = {32714148},
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@article{alivernini2020-32601335,
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  title   = {{Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis}},
  journal = {Nature medicine},
  year    = {2020},
  doi     = {10.1038/s41591-020-0939-8},
  pmid    = {32601335},
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@article{petersvanton2020-32592865,
  author  = {Peters van Ton, A. M. and Verbeek, M. M. and Alkema, W. and Pickkers, P. and Abdo, W. F.},
  title   = {{Downregulation of synapse-associated protein expression and loss of homeostatic microglial control in cerebrospinal fluid of infectious patients with delirium and patients with Alzheimer's disease}},
  journal = {Brain, behavior, and immunity},
  year    = {2020},
  doi     = {10.1016/j.bbi.2020.06.027},
  pmid    = {32592865},
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@article{riad2020-32572762,
  author  = {Riad, A. and Lengyel-Zhand, Z. and Zeng, C. and Weng, C. C. and Lee, V. M. and Trojanowski, J. Q. and Mach, R. H.},
  title   = {{The Sigma-2 Receptor/TMEM97, PGRMC1, and LDL Receptor Complex Are Responsible for the Cellular Uptake of Aβ42 and Its Protein Aggregates}},
  journal = {Molecular neurobiology},
  year    = {2020},
  doi     = {10.1007/s12035-020-01988-1},
  pmid    = {32572762},
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@article{jahangard2020-32625049,
  author  = {Jahangard, Y. and Monfared, H. and Moradi, A. and Zare, M. and Mirnajafi-Zadeh, J. and Mowla, S. J.},
  title   = {{Therapeutic Effects of Transplanted Exosomes Containing miR-29b to a Rat Model of Alzheimer's Disease}},
  journal = {Frontiers in neuroscience},
  year    = {2020},
  doi     = {10.3389/fnins.2020.00564},
  pmid    = {32625049},
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@article{puigdellivol2020-32581723,
  author  = {Puigdellívol, M. and Allendorf, D. H. and Brown, G. C.},
  title   = {{Sialylation and Galectin-3 in Microglia-Mediated Neuroinflammation and Neurodegeneration}},
  journal = {Frontiers in cellular neuroscience},
  year    = {2020},
  doi     = {10.3389/fncel.2020.00162},
  pmid    = {32581723},
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@article{wang2020-32493725,
  author  = {Wang, X. and Li, W. and Marcus, J. and Pearson, M. and Song, L. and Smith, K. and Terracina, G. and Lee, J. and others},
  title   = {{MK-8719, a Novel and Selective O-GlcNAcase Inhibitor That Reduces the Formation of Pathological Tau and Ameliorates Neurodegeneration in a Mouse Model of Tauopathy}},
  journal = {The Journal of pharmacology and experimental therapeutics},
  year    = {2020},
  doi     = {10.1124/jpet.120.266122},
  pmid    = {32493725},
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@article{burberry2020-32483373,
  author  = {Burberry, A. and Wells, M. F. and Limone, F. and Couto, A. and Smith, K. S. and Keaney, J. and Gillet, G. and van Gastel, N. and others},
  title   = {{C9orf72 suppresses systemic and neural inflammation induced by gut bacteria}},
  journal = {Nature},
  year    = {2020},
  doi     = {10.1038/s41586-020-2288-7},
  pmid    = {32483373},
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@article{guan2020-32413556,
  author  = {Guan, Y. F. and Huang, G. B. and Xu, M. D. and Gao, F. and Lin, S. and Huang, J. and Wang, J. and Li, Y. Q. and others},
  title   = {{Anti-depression effects of ketogenic diet are mediated via the restoration of microglial activation and neuronal excitability in the lateral habenula}},
  journal = {Brain, behavior, and immunity},
  year    = {2020},
  doi     = {10.1016/j.bbi.2020.05.032},
  pmid    = {32413556},
  url     = {https://doi.org/10.1016/j.bbi.2020.05.032}
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@article{seidman2020-32362324,
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  title   = {{Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis}},
  journal = {Immunity},
  year    = {2020},
  doi     = {10.1016/j.immuni.2020.04.001},
  pmid    = {32362324},
  url     = {https://doi.org/10.1016/j.immuni.2020.04.001}
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@article{rossi2020-32342188,
  author  = {Rossi, M. and Candelise, N. and Baiardi, S. and Capellari, S. and Giannini, G. and Orrù, C. D. and Antelmi, E. and Mammana, A. and others},
  title   = {{Ultrasensitive RT-QuIC assay with high sensitivity and specificity for Lewy body-associated synucleinopathies}},
  journal = {Acta neuropathologica},
  year    = {2020},
  doi     = {10.1007/s00401-020-02160-8},
  pmid    = {32342188},
  url     = {https://doi.org/10.1007/s00401-020-02160-8}
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@article{muller2020-32326586,
  author  = {Müller, P. and Duderstadt, Y. and Lessmann, V. and Müller, N. G.},
  title   = {{Lactate and BDNF: Key Mediators of Exercise Induced Neuroplasticity?}},
  journal = {Journal of clinical medicine},
  year    = {2020},
  doi     = {10.3390/jcm9041136},
  pmid    = {32326586},
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@article{derossi2020-32160554,
  author  = {De Rossi, P. and Nomura, T. and Andrew, R. J. and Masse, N. Y. and Sampathkumar, V. and Musial, T. F. and Sudwarts, A. and Recupero, A. J. and others},
  title   = {{Neuronal BIN1 Regulates Presynaptic Neurotransmitter Release and Memory Consolidation}},
  journal = {Cell reports},
  year    = {2020},
  doi     = {10.1016/j.celrep.2020.02.026},
  pmid    = {32160554},
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@article{acero2020-32114116,
  author  = {Acero, G. and Garay, C. and Venegas, D. and Ortega, E. and Gevorkian, G.},
  title   = {{Novel monoclonal antibody 3B8 specifically recognizes pyroglutamate-modified amyloid β 3-42 peptide in brain of AD patients and 3xTg-AD transgenic mice}},
  journal = {Neuroscience letters},
  year    = {2020},
  doi     = {10.1016/j.neulet.2020.134876},
  pmid    = {32114116},
  url     = {https://doi.org/10.1016/j.neulet.2020.134876}
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@article{yao2021-32048886,
  author  = {Yao, R. Q. and Ren, C. and Xia, Z. F. and Yao, Y. M.},
  title   = {{Organelle-specific autophagy in inflammatory diseases: a potential therapeutic target underlying the quality control of multiple organelles}},
  journal = {Autophagy},
  year    = {2021},
  doi     = {10.1080/15548627.2020.1725377},
  pmid    = {32048886},
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}

@article{han2020-32194838,
  author  = {Han, B. and Jiang, W. and Liu, H. and Wang, J. and Zheng, K. and Cui, P. and Feng, Y. and Dang, C. and others},
  title   = {{Upregulation of neuronal PGC-1α ameliorates cognitive impairment induced by chronic cerebral hypoperfusion}},
  journal = {Theranostics},
  year    = {2020},
  doi     = {10.7150/thno.37119},
  pmid    = {32194838},
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}

@article{tsai2020-31710340,
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  title   = {{Reactions to Multiple Ascending Doses of the Microtubule Stabilizer TPI-287 in Patients With Alzheimer Disease, Progressive Supranuclear Palsy, and Corticobasal Syndrome: A Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2020},
  doi     = {10.1001/jamaneurol.2019.3812},
  pmid    = {31710340},
  url     = {https://doi.org/10.1001/jamaneurol.2019.3812}
}

@article{jackson2020-32000838,
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  title   = {{Elevated methylation levels, reduced expression levels, and frequent contractions in a clinical cohort of C9orf72 expansion carriers}},
  journal = {Molecular neurodegeneration},
  year    = {2020},
  doi     = {10.1186/s13024-020-0359-8},
  pmid    = {32000838},
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}

@article{wang2020-31997558,
  author  = {Wang, F. and Zhang, Z. Z. and Cao, L. and Yang, Q. G. and Lu, Q. F. and Chen, G. H.},
  title   = {{Lipopolysaccharide exposure during late embryogenesis triggers and drives Alzheimer-like behavioral and neuropathological changes in CD-1 mice}},
  journal = {Brain and behavior},
  year    = {2020},
  doi     = {10.1002/brb3.1546},
  pmid    = {31997558},
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}

@article{vanveen2020-31996848,
  author  = {van Veen, S. and Martin, S. and Van den Haute, C. and Benoy, V. and Lyons, J. and Vanhoutte, R. and Kahler, J. P. and Decuypere, J. P. and others},
  title   = {{ATP13A2 deficiency disrupts lysosomal polyamine export}},
  journal = {Nature},
  year    = {2020},
  doi     = {10.1038/s41586-020-1968-7},
  pmid    = {31996848},
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@article{fang2019-32009956,
  author  = {Fang, K. and Li, H. R. and Chen, X. X. and Gao, X. R. and Huang, L. L. and Du, A. Q. and Jiang, C. and Li, H. and others},
  title   = {{Quercetin Alleviates LPS-Induced Depression-Like Behavior in Rats via Regulating BDNF-Related Imbalance of Copine 6 and TREM1/2 in the Hippocampus and PFC}},
  journal = {Frontiers in pharmacology},
  year    = {2019},
  doi     = {10.3389/fphar.2019.01544},
  pmid    = {32009956},
  url     = {https://doi.org/10.3389/fphar.2019.01544}
}

@article{heller2020-31937580,
  author  = {Heller, C. and Foiani, M. S. and Moore, K. and Convery, R. and Bocchetta, M. and Neason, M. and Cash, D. M. and Thomas, D. and others},
  title   = {{Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia}},
  journal = {Journal of neurology, neurosurgery, and psychiatry},
  year    = {2020},
  doi     = {10.1136/jnnp-2019-321954},
  pmid    = {31937580},
  url     = {https://doi.org/10.1136/jnnp-2019-321954}
}

@article{zhang2020-32000403,
  author  = {Zhang, B. and Li, R. and Zhang, Y. and Gao, X.},
  title   = {{Differential role of triggering receptors expressed on myeloid cells 2 R47H in 3 neurodegenerative diseases based on a systematic review and meta-analysis}},
  journal = {Medicine},
  year    = {2020},
  doi     = {10.1097/md.0000000000018921},
  pmid    = {32000403},
  url     = {https://doi.org/10.1097/md.0000000000018921}
}

@article{gallardofernandez2019-31906130,
  author  = {Gallardo-Fernández, M. and Hornedo-Ortega, R. and Alonso-Bellido, I. M. and Rodríguez-Gómez, J. A. and Troncoso, A. M. and García-Parrilla, M. C. and Venero, J. L. and Espinosa-Oliva, A. M. and others},
  title   = {{Hydroxytyrosol Decreases LPS- and α-Synuclein-Induced Microglial Activation In Vitro}},
  journal = {Antioxidants (Basel, Switzerland)},
  year    = {2019},
  doi     = {10.3390/antiox9010036},
  pmid    = {31906130},
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}

@article{henderson2020-31899072,
  author  = {Henderson, M. X. and Sedor, S. and McGeary, I. and Cornblath, E. J. and Peng, C. and Riddle, D. M. and Li, H. L. and Zhang, B. and others},
  title   = {{Glucocerebrosidase Activity Modulates Neuronal Susceptibility to Pathological α-Synuclein Insult}},
  journal = {Neuron},
  year    = {2020},
  doi     = {10.1016/j.neuron.2019.12.004},
  pmid    = {31899072},
  url     = {https://doi.org/10.1016/j.neuron.2019.12.004}
}

@article{banihani2020-31993180,
  author  = {Banihani, S. A. and Fashtaky, R. A. and Makahleh, S. M. and El-Akawi, Z. J. and Khabour, O. F. and Saadeh, N. A.},
  title   = {{Effect of fresh pomegranate juice on the level of melatonin, insulin, and fasting serum glucose in healthy individuals and people with impaired fasting glucose}},
  journal = {Food science \& nutrition},
  year    = {2020},
  doi     = {10.1002/fsn3.1344},
  pmid    = {31993180},
  url     = {https://doi.org/10.1002/fsn3.1344}
}

@article{zhou2019-31843022,
  author  = {Zhou, L. and Flores, J. and Noël, A. and Beauchet, O. and Sjöström, P. J. and LeBlanc, A. C.},
  title   = {{Methylene blue inhibits Caspase-6 activity, and reverses Caspase-6-induced cognitive impairment and neuroinflammation in aged mice}},
  journal = {Acta neuropathologica communications},
  year    = {2019},
  doi     = {10.1186/s40478-019-0856-6},
  pmid    = {31843022},
  url     = {https://doi.org/10.1186/s40478-019-0856-6}
}

@article{lee2020-31800167,
  author  = {Lee, J. and Kim, D. E. and Griffin, P. and Sheehan, P. W. and Kim, D. H. and Musiek, E. S. and Yoon, S. Y.},
  title   = {{Inhibition of REV-ERBs stimulates microglial amyloid-beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer's disease}},
  journal = {Aging cell},
  year    = {2020},
  doi     = {10.1111/acel.13078},
  pmid    = {31800167},
  url     = {https://doi.org/10.1111/acel.13078}
}

@article{bocchetta2020-31696638,
  author  = {Bocchetta, M. and Iglesias, J. E. and Neason, M. and Cash, D. M. and Warren, J. D. and Rohrer, J. D.},
  title   = {{Thalamic nuclei in frontotemporal dementia: Mediodorsal nucleus involvement is universal but pulvinar atrophy is unique to C9orf72}},
  journal = {Human brain mapping},
  year    = {2020},
  doi     = {10.1002/hbm.24856},
  pmid    = {31696638},
  url     = {https://doi.org/10.1002/hbm.24856}
}

@article{yamazaki2020-31665905,
  author  = {Yamazaki, Y. and Shinohara, M. and Yamazaki, A. and Ren, Y. and Asmann, Y. W. and Kanekiyo, T. and Bu, G.},
  title   = {{ApoE (Apolipoprotein E) in Brain Pericytes Regulates Endothelial Function in an Isoform-Dependent Manner by Modulating Basement Membrane Components}},
  journal = {Arteriosclerosis, thrombosis, and vascular biology},
  year    = {2020},
  doi     = {10.1161/atvbaha.119.313169},
  pmid    = {31665905},
  url     = {https://doi.org/10.1161/atvbaha.119.313169}
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@article{bruch2019-31663165,
  author  = {Bruch, R. and Baaske, J. and Chatelle, C. and Meirich, M. and Madlener, S. and Weber, W. and Dincer, C. and Urban, G. A.},
  title   = {{CRISPR/Cas13a-Powered Electrochemical Microfluidic Biosensor for Nucleic Acid Amplification-Free miRNA Diagnostics}},
  journal = {Advanced materials (Deerfield Beach, Fla.)},
  year    = {2019},
  doi     = {10.1002/adma.201905311},
  pmid    = {31663165},
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}

@article{zhang2019-31590042,
  author  = {Zhang, J. and Zheng, Y. and Luo, Y. and Du, Y. and Zhang, X. and Fu, J.},
  title   = {{Curcumin inhibits LPS-induced neuroinflammation by promoting microglial M2 polarization via TREM2/ TLR4/ NF-κB pathways in BV2 cells}},
  journal = {Molecular immunology},
  year    = {2019},
  doi     = {10.1016/j.molimm.2019.09.020},
  pmid    = {31590042},
  url     = {https://doi.org/10.1016/j.molimm.2019.09.020}
}

@article{ruegsegger2019-31534057,
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  title   = {{Exercise and metformin counteract altered mitochondrial function in the insulin-resistant brain}},
  journal = {JCI insight},
  year    = {2019},
  doi     = {10.1172/jci.insight.130681},
  pmid    = {31534057},
  url     = {https://doi.org/10.1172/jci.insight.130681}
}

@article{allen2019-31484829,
  author  = {Allen, M. D. and Springer, D. A. and Burg, M. B. and Boehm, M. and Dmitrieva, N. I.},
  title   = {{Suboptimal hydration remodels metabolism, promotes degenerative diseases, and shortens life}},
  journal = {JCI insight},
  year    = {2019},
  doi     = {10.1172/jci.insight.130949},
  pmid    = {31484829},
  url     = {https://doi.org/10.1172/jci.insight.130949}
}

@article{sun2019-31383855,
  author  = {Sun, J. and Xu, J. and Ling, Y. and Wang, F. and Gong, T. and Yang, C. and Ye, S. and Ye, K. and others},
  title   = {{Fecal microbiota transplantation alleviated Alzheimer's disease-like pathogenesis in APP/PS1 transgenic mice}},
  journal = {Translational psychiatry},
  year    = {2019},
  doi     = {10.1038/s41398-019-0525-3},
  pmid    = {31383855},
  url     = {https://doi.org/10.1038/s41398-019-0525-3}
}

@article{tejera2019-31359456,
  author  = {Tejera, D. and Mercan, D. and Sanchez-Caro, J. M. and Hanan, M. and Greenberg, D. and Soreq, H. and Latz, E. and Golenbock, D. and others},
  title   = {{Systemic inflammation impairs microglial Aβ clearance through NLRP3 inflammasome}},
  journal = {The EMBO journal},
  year    = {2019},
  doi     = {10.15252/embj.2018101064},
  pmid    = {31359456},
  url     = {https://doi.org/10.15252/embj.2018101064}
}

@article{gao2019-31301160,
  author  = {Gao, T. and Jernigan, J. and Raza, S. A. and Dammer, E. B. and Xiao, H. and Seyfried, N. T. and Levey, A. I. and Rangaraju, S.},
  title   = {{Transcriptional regulation of homeostatic and disease-associated-microglial genes by IRF1, LXRβ, and CEBPα}},
  journal = {Glia},
  year    = {2019},
  doi     = {10.1002/glia.23678},
  pmid    = {31301160},
  url     = {https://doi.org/10.1002/glia.23678}
}

@article{fang2019-31272829,
  author  = {Fang, M. Y. and Markmiller, S. and Vu, A. Q. and Javaherian, A. and Dowdle, W. E. and Jolivet, P. and Bushway, P. J. and Castello, N. A. and others},
  title   = {{Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD}},
  journal = {Neuron},
  year    = {2019},
  doi     = {10.1016/j.neuron.2019.05.048},
  pmid    = {31272829},
  url     = {https://doi.org/10.1016/j.neuron.2019.05.048}
}

@article{vanderlee2019-31131421,
  author  = {van der Lee, S. J. and Conway, O. J. and Jansen, I. and Carrasquillo, M. M. and Kleineidam, L. and van den Akker, E. and Hernández, I. and van Eijk, K. R. and others},
  title   = {{A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity}},
  journal = {Acta neuropathologica},
  year    = {2019},
  doi     = {10.1007/s00401-019-02026-8},
  pmid    = {31131421},
  url     = {https://doi.org/10.1007/s00401-019-02026-8}
}

@article{choi2019-31086314,
  author  = {Choi, S. Y. and Lopez-Gonzalez, R. and Krishnan, G. and Phillips, H. L. and Li, A. N. and Seeley, W. W. and Yao, W. D. and Almeida, S. and others},
  title   = {{C9ORF72-ALS/FTD-associated poly(GR) binds Atp5a1 and compromises mitochondrial function in vivo}},
  journal = {Nature neuroscience},
  year    = {2019},
  doi     = {10.1038/s41593-019-0397-0},
  pmid    = {31086314},
  url     = {https://doi.org/10.1038/s41593-019-0397-0}
}

@article{adaikkan2019-31076275,
  author  = {Adaikkan, C. and Middleton, S. J. and Marco, A. and Pao, P. C. and Mathys, H. and Kim, D. N. and Gao, F. and Young, J. Z. and others},
  title   = {{Gamma Entrainment Binds Higher-Order Brain Regions and Offers Neuroprotection}},
  journal = {Neuron},
  year    = {2019},
  doi     = {10.1016/j.neuron.2019.04.011},
  pmid    = {31076275},
  url     = {https://doi.org/10.1016/j.neuron.2019.04.011}
}

@article{anderson2019-31091440,
  author  = {Anderson, SR. and Roberts, J. M. and Zhang, J. and Steele, M. R. and Romero, C. O. and Bosco, A. and Vetter, M. L.},
  title   = {{Developmental Apoptosis Promotes a Disease-Related Gene Signature and Independence from CSF1R Signaling in Retinal Microglia}},
  journal = {Cell reports},
  year    = {2019},
  doi     = {10.1016/j.celrep.2019.04.062},
  pmid    = {31091440},
  url     = {https://doi.org/10.1016/j.celrep.2019.04.062}
}

@article{inoue2019-31036637,
  author  = {Inoue, T. and Saito, S. and Tanaka, M. and Yamakage, H. and Kusakabe, T. and Shimatsu, A. and Ihara, M. and Satoh-Asahara, N.},
  title   = {{Pleiotropic neuroprotective effects of taxifolin in cerebral amyloid angiopathy}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2019},
  doi     = {10.1073/pnas.1901659116},
  pmid    = {31036637},
  url     = {https://doi.org/10.1073/pnas.1901659116}
}

@article{zafeer2019-31029786,
  author  = {Zafeer, M. F. and Firdaus, F. and Anis, E. and Mobarak Hossain, M.},
  title   = {{Prolong treatment with Trans-ferulic acid mitigates bioenergetics loss and restores mitochondrial dynamics in streptozotocin-induced sporadic dementia of Alzheimer's type}},
  journal = {Neurotoxicology},
  year    = {2019},
  doi     = {10.1016/j.neuro.2019.04.006},
  pmid    = {31029786},
  url     = {https://doi.org/10.1016/j.neuro.2019.04.006}
}

@article{wani2019-30894052,
  author  = {Wani, A. and Gupta, M. and Ahmad, M. and Shah, A. M. and Ahsan, A. U. and Qazi, P. H. and Malik, F. and Singh, G. and others},
  title   = {{Alborixin clears amyloid-β by inducing autophagy through PTEN-mediated inhibition of the AKT pathway}},
  journal = {Autophagy},
  year    = {2019},
  doi     = {10.1080/15548627.2019.1596476},
  pmid    = {30894052},
  url     = {https://doi.org/10.1080/15548627.2019.1596476}
}

@article{chalatsa2019-30971876,
  author  = {Chalatsa, I. and Arvanitis, D. A. and Koulakiotis, N. S. and Giagini, A. and Skaltsounis, A. L. and Papadopoulou-Daifoti, Z. and Tsarbopoulos, A. and Sanoudou, D.},
  title   = {{The Crocus sativus Compounds trans-Crocin 4 and trans-Crocetin Modulate the Amyloidogenic Pathway and Tau Misprocessing in Alzheimer Disease Neuronal Cell Culture Models}},
  journal = {Frontiers in neuroscience},
  year    = {2019},
  doi     = {10.3389/fnins.2019.00249},
  pmid    = {30971876},
  url     = {https://doi.org/10.3389/fnins.2019.00249}
}

@article{muhammad2019-30884890,
  author  = {Muhammad, T. and Ikram, M. and Ullah, R. and Rehman, S. U. and Kim, M. O.},
  title   = {{RETRACTED: Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-κB Signaling}},
  journal = {Nutrients},
  year    = {2019},
  doi     = {10.3390/nu11030648},
  pmid    = {30884890},
  url     = {https://doi.org/10.3390/nu11030648}
}

@article{didomenico2019-30876754,
  author  = {Di Domenico, F. and Tramutola, A. and Barone, E. and Lanzillotta, C. and Defever, O. and Arena, A. and Zuliani, I. and Foppoli, C. and others},
  title   = {{Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome}},
  journal = {Redox biology},
  year    = {2019},
  doi     = {10.1016/j.redox.2019.101162},
  pmid    = {30876754},
  url     = {https://doi.org/10.1016/j.redox.2019.101162}
}

@article{gassetrosa2019-30853299,
  author  = {Gasset-Rosa, F. and Lu, S. and Yu, H. and Chen, C. and Melamed, Z. and Guo, L. and Shorter, J. and Da Cruz, S. and others},
  title   = {{Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death}},
  journal = {Neuron},
  year    = {2019},
  doi     = {10.1016/j.neuron.2019.02.038},
  pmid    = {30853299},
  url     = {https://doi.org/10.1016/j.neuron.2019.02.038}
}

@article{gomezsuaga2019-30841933,
  author  = {Gómez-Suaga, P. and Pérez-Nievas, B. G. and Glennon, E. B. and Lau, D. H. W. and Paillusson, S. and Mórotz, G. M. and Calì, T. and Pizzo, P. and others},
  title   = {{The VAPB-PTPIP51 endoplasmic reticulum-mitochondria tethering proteins are present in neuronal synapses and regulate synaptic activity}},
  journal = {Acta neuropathologica communications},
  year    = {2019},
  doi     = {10.1186/s40478-019-0688-4},
  pmid    = {30841933},
  url     = {https://doi.org/10.1186/s40478-019-0688-4}
}

@article{mathews2019-30832693,
  author  = {Mathews, S. and Branch Woods, A. and Katano, I. and Makarov, E. and Thomas, M. B. and Gendelman, H. E. and Poluektova, L. Y. and Ito, M. and others},
  title   = {{Human Interleukin-34 facilitates microglia-like cell differentiation and persistent HIV-1 infection in humanized mice}},
  journal = {Molecular neurodegeneration},
  year    = {2019},
  doi     = {10.1186/s13024-019-0311-y},
  pmid    = {30832693},
  url     = {https://doi.org/10.1186/s13024-019-0311-y}
}

@article{hernandez2019-30918111,
  author  = {Hernandez, I. and Luna, G. and Rauch, J. N. and Reis, S. A. and Giroux, M. and Karch, C. M. and Boctor, D. and Sibih, Y. E. and others},
  title   = {{A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy}},
  journal = {Science translational medicine},
  year    = {2019},
  doi     = {10.1126/scitranslmed.aat3005},
  pmid    = {30918111},
  url     = {https://doi.org/10.1126/scitranslmed.aat3005}
}

@article{mann2019-30826182,
  author  = {Mann, JR. and Gleixner, A. M. and Mauna, J. C. and Gomes, E. and DeChellis-Marks, M. R. and Needham, P. G. and Copley, K. E. and Hurtle, B. and others},
  title   = {{RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43}},
  journal = {Neuron},
  year    = {2019},
  doi     = {10.1016/j.neuron.2019.01.048},
  pmid    = {30826182},
  url     = {https://doi.org/10.1016/j.neuron.2019.01.048}
}

@article{babinchak2019-30814253,
  author  = {Babinchak, W. M. and Haider, R. and Dumm, B. K. and Sarkar, P. and Surewicz, K. and Choi, J. K. and Surewicz, W. K.},
  title   = {{The role of liquid-liquid phase separation in aggregation of the TDP-43 low-complexity domain}},
  journal = {The Journal of biological chemistry},
  year    = {2019},
  doi     = {10.1074/jbc.ra118.007222},
  pmid    = {30814253},
  url     = {https://doi.org/10.1074/jbc.ra118.007222}
}

@article{chew2019-30767771,
  author  = {Chew, J. and Cook, C. and Gendron, T. F. and Jansen-West, K. and Del Rosso, G. and Daughrity, L. M. and Castanedes-Casey, M. and Kurti, A. and others},
  title   = {{Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy}},
  journal = {Molecular neurodegeneration},
  year    = {2019},
  doi     = {10.1186/s13024-019-0310-z},
  pmid    = {30767771},
  url     = {https://doi.org/10.1186/s13024-019-0310-z}
}

@article{prasad2019-30837838,
  author  = {Prasad, A. and Bharathi, V. and Sivalingam, V. and Girdhar, A. and Patel, B. K.},
  title   = {{Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis}},
  journal = {Frontiers in molecular neuroscience},
  year    = {2019},
  doi     = {10.3389/fnmol.2019.00025},
  pmid    = {30837838},
  url     = {https://doi.org/10.3389/fnmol.2019.00025}
}

@article{duan2019-30728452,
  author  = {Duan, Y. and Du, A. and Gu, J. and Duan, G. and Wang, C. and Gui, X. and Ma, Z. and Qian, B. and others},
  title   = {{PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins}},
  journal = {Cell research},
  year    = {2019},
  doi     = {10.1038/s41422-019-0141-z},
  pmid    = {30728452},
  url     = {https://doi.org/10.1038/s41422-019-0141-z}
}

@article{depins2019-30700530,
  author  = {de Pins, B. and Cifuentes-Díaz, C. and Farah, A. T. and López-Molina, L. and Montalban, E. and Sancho-Balsells, A. and López, A. and Ginés, S. and others},
  title   = {{Conditional BDNF Delivery from Astrocytes Rescues Memory Deficits, Spine Density, and Synaptic Properties in the 5xFAD Mouse Model of Alzheimer Disease}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2019},
  doi     = {10.1523/jneurosci.2121-18.2019},
  pmid    = {30700530},
  url     = {https://doi.org/10.1523/jneurosci.2121-18.2019}
}

@article{rosenzweig2019-30692527,
  author  = {Rosenzweig, N. and Dvir-Szternfeld, R. and Tsitsou-Kampeli, A. and Keren-Shaul, H. and Ben-Yehuda, H. and Weill-Raynal, P. and Cahalon, L. and Kertser, A. and others},
  title   = {{PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model}},
  journal = {Nature communications},
  year    = {2019},
  doi     = {10.1038/s41467-019-08352-5},
  pmid    = {30692527},
  url     = {https://doi.org/10.1038/s41467-019-08352-5}
}

@article{nazmi2019-30680794,
  author  = {Nazmi, A. and Field, R. H. and Griffin, E. W. and Haugh, O. and Hennessy, E. and Cox, D. and Reis, R. and Tortorelli, L. and others},
  title   = {{Chronic neurodegeneration induces type I interferon synthesis via STING, shaping microglial phenotype and accelerating disease progression}},
  journal = {Glia},
  year    = {2019},
  doi     = {10.1002/glia.23592},
  pmid    = {30680794},
  url     = {https://doi.org/10.1002/glia.23592}
}

@article{melamed2019-30643298,
  author  = {Melamed, Z. and López-Erauskin, J. and Baughn, M. W. and Zhang, O. and Drenner, K. and Sun, Y. and Freyermuth, F. and McMahon, M. A. and others},
  title   = {{Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration}},
  journal = {Nature neuroscience},
  year    = {2019},
  doi     = {10.1038/s41593-018-0293-z},
  pmid    = {30643298},
  url     = {https://doi.org/10.1038/s41593-018-0293-z}
}

@article{yuan2019-30467385,
  author  = {Yuan, J. and Amin, P. and Ofengeim, D.},
  title   = {{Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases}},
  journal = {Nature reviews. Neuroscience},
  year    = {2019},
  doi     = {10.1038/s41583-018-0093-1},
  pmid    = {30467385},
  url     = {https://doi.org/10.1038/s41583-018-0093-1}
}

@article{jiang2018-30546007,
  author  = {Jiang, S. and Wen, N. and Li, Z. and Dube, U. and Del Aguila, J. and Budde, J. and Martinez, R. and Hsu, S. and others},
  title   = {{Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP}},
  journal = {Translational psychiatry},
  year    = {2018},
  doi     = {10.1038/s41398-018-0319-z},
  pmid    = {30546007},
  url     = {https://doi.org/10.1038/s41398-018-0319-z}
}

@article{kurisu2019-30523715,
  author  = {Kurisu, K. and Zheng, Z. and Kim, J. Y. and Shi, J. and Kanoke, A. and Liu, J. and Hsieh, C. L. and Yenari, M. A.},
  title   = {{Triggering receptor expressed on myeloid cells-2 expression in the brain is required for maximal phagocytic activity and improved neurological outcomes following experimental stroke}},
  journal = {Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year    = {2019},
  doi     = {10.1177/0271678x18817282},
  pmid    = {30523715},
  url     = {https://doi.org/10.1177/0271678x18817282}
}

@article{fleitas2018-30428894,
  author  = {Fleitas, C. and Piñol-Ripoll, G. and Marfull, P. and Rocandio, D. and Ferrer, I. and Rampon, C. and Egea, J. and Espinet, C.},
  title   = {{proBDNF is modified by advanced glycation end products in Alzheimer's disease and causes neuronal apoptosis by inducing p75 neurotrophin receptor processing}},
  journal = {Molecular brain},
  year    = {2018},
  doi     = {10.1186/s13041-018-0411-6},
  pmid    = {30428894},
  url     = {https://doi.org/10.1186/s13041-018-0411-6}
}

@article{wennberg2018-30422173,
  author  = {Wennberg, A. M. and Tosakulwong, N. and Lesnick, T. G. and Murray, M. E. and Whitwell, J. L. and Liesinger, A. M. and Petrucelli, L. and Boeve, B. F. and others},
  title   = {{Association of Apolipoprotein E ε4 With Transactive Response DNA-Binding Protein 43}},
  journal = {JAMA neurology},
  year    = {2018},
  doi     = {10.1001/jamaneurol.2018.3139},
  pmid    = {30422173},
  url     = {https://doi.org/10.1001/jamaneurol.2018.3139}
}

@article{lopezerauskin2018-30344044,
  author  = {López-Erauskin, J. and Tadokoro, T. and Baughn, M. W. and Myers, B. and McAlonis-Downes, M. and Chillon-Marinas, C. and Asiaban, J. N. and Artates, J. and others},
  title   = {{ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS}},
  journal = {Neuron},
  year    = {2018},
  doi     = {10.1016/j.neuron.2018.09.044},
  pmid    = {30344044},
  url     = {https://doi.org/10.1016/j.neuron.2018.09.044}
}

@article{audrain2019-30283031,
  author  = {Audrain, M. and Haure-Mirande, J. V. and Wang, M. and Kim, S. H. and Fanutza, T. and Chakrabarty, P. and Fraser, P. and St George-Hyslop, P. H. and others},
  title   = {{Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and state of phosphorylation of tau}},
  journal = {Molecular psychiatry},
  year    = {2019},
  doi     = {10.1038/s41380-018-0258-3},
  pmid    = {30283031},
  url     = {https://doi.org/10.1038/s41380-018-0258-3}
}

@article{yang2018-30273629,
  author  = {Yang, L. and Jin, P. and Wang, X. and Zhou, Q. and Lin, X. and Xi, S.},
  title   = {{Fluoride activates microglia, secretes inflammatory factors and influences synaptic neuron plasticity in the hippocampus of rats}},
  journal = {Neurotoxicology},
  year    = {2018},
  doi     = {10.1016/j.neuro.2018.09.006},
  pmid    = {30273629},
  url     = {https://doi.org/10.1016/j.neuro.2018.09.006}
}

@article{flores2018-30254377,
  author  = {Flores, J. and Noël, A. and Foveau, B. and Lynham, J. and Lecrux, C. and LeBlanc, A. C.},
  title   = {{Caspase-1 inhibition alleviates cognitive impairment and neuropathology in an Alzheimer's disease mouse model}},
  journal = {Nature communications},
  year    = {2018},
  doi     = {10.1038/s41467-018-06449-x},
  pmid    = {30254377},
  url     = {https://doi.org/10.1038/s41467-018-06449-x}
}

@article{xu2018-30146158,
  author  = {Xu, D. and Jin, T. and Zhu, H. and Chen, H. and Ofengeim, D. and Zou, C. and Mifflin, L. and Pan, L. and others},
  title   = {{TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging}},
  journal = {Cell},
  year    = {2018},
  doi     = {10.1016/j.cell.2018.07.041},
  pmid    = {30146158},
  url     = {https://doi.org/10.1016/j.cell.2018.07.041}
}

@article{zhang2018-30115118,
  author  = {Zhang, H. and Therriault, J. and Kang, M. S. and Ng, K. P. and Pascoal, T. A. and Rosa-Neto, P. and Gauthier, S. and {Alzheimer’s Disease Neuroimaging Initiative}},
  title   = {{Cerebrospinal fluid synaptosomal-associated protein 25 is a key player in synaptic degeneration in mild cognitive impairment and Alzheimer's disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2018},
  doi     = {10.1186/s13195-018-0407-6},
  pmid    = {30115118},
  url     = {https://doi.org/10.1186/s13195-018-0407-6}
}

@article{kim2018-30092810,
  author  = {Kim, C. and Spencer, B. and Rockenstein, E. and Yamakado, H. and Mante, M. and Adame, A. and Fields, J. A. and Masliah, D. and others},
  title   = {{Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation}},
  journal = {Molecular neurodegeneration},
  year    = {2018},
  doi     = {10.1186/s13024-018-0276-2},
  pmid    = {30092810},
  url     = {https://doi.org/10.1186/s13024-018-0276-2}
}

@article{mcgurk2018-30100264,
  author  = {McGurk, L. and Gomes, E. and Guo, L. and Mojsilovic-Petrovic, J. and Tran, V. and Kalb, R. G. and Shorter, J. and Bonini, N. M.},
  title   = {{Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization}},
  journal = {Molecular cell},
  year    = {2018},
  doi     = {10.1016/j.molcel.2018.07.002},
  pmid    = {30100264},
  url     = {https://doi.org/10.1016/j.molcel.2018.07.002}
}

@article{tapias2018-29860433,
  author  = {Tapias, V. and Jainuddin, S. and Ahuja, M. and Stack, C. and Elipenahli, C. and Vignisse, J. and Gerges, M. and Starkova, N. and others},
  title   = {{Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy}},
  journal = {Human molecular genetics},
  year    = {2018},
  doi     = {10.1093/hmg/ddy201},
  pmid    = {29860433},
  url     = {https://doi.org/10.1093/hmg/ddy201}
}

@article{diaz2018-30154946,
  author  = {Diaz, A. and Escobedo, C. and Treviño, S. and Chávez, R. and Lopez-Lopez, G. and Moran, C. and Guevara, J. and Venegas, B. and others},
  title   = {{Metabolic Syndrome Exacerbates the Recognition Memory Impairment and Oxidative-Inflammatory Response in Rats with an Intrahippocampal Injection of Amyloid Beta 1-42}},
  journal = {Oxidative medicine and cellular longevity},
  year    = {2018},
  doi     = {10.1155/2018/1358057},
  pmid    = {30154946},
  url     = {https://doi.org/10.1155/2018/1358057}
}

@article{seitz2018-29899084,
  author  = {Seitz, S. and Clarke, P. and Tyler, K. L.},
  title   = {{Pharmacologic Depletion of Microglia Increases Viral Load in the Brain and Enhances Mortality in Murine Models of Flavivirus-Induced Encephalitis}},
  journal = {Journal of virology},
  year    = {2018},
  doi     = {10.1128/jvi.00525-18},
  pmid    = {29899084},
  url     = {https://doi.org/10.1128/jvi.00525-18}
}

@article{hou2018-29947276,
  author  = {Hou, X. and Fiesel, F. C. and Truban, D. and Castanedes Casey, M. and Lin, W. L. and Soto, A. I. and Tacik, P. and Rousseau, L. G. and others},
  title   = {{Age- and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body disease}},
  journal = {Autophagy},
  year    = {2018},
  doi     = {10.1080/15548627.2018.1461294},
  pmid    = {29947276},
  url     = {https://doi.org/10.1080/15548627.2018.1461294}
}

@article{hoveizi2018-30025963,
  author  = {Hoveizi, E. and Mohammadi, T. and Moazedi, A. A. and Zamani, N. and Eskandary, A.},
  title   = {{Transplanted neural-like cells improve memory and Alzheimer-like pathology in a rat model}},
  journal = {Cytotherapy},
  year    = {2018},
  doi     = {10.1016/j.jcyt.2018.03.036},
  pmid    = {30025963},
  url     = {https://doi.org/10.1016/j.jcyt.2018.03.036}
}

@article{rojo2018-30029164,
  author  = {Rojo, A. I. and Pajares, M. and García-Yagüe, A. J. and Buendia, I. and Van Leuven, F. and Yamamoto, M. and López, M. G. and Cuadrado, A.},
  title   = {{Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathy}},
  journal = {Redox biology},
  year    = {2018},
  doi     = {10.1016/j.redox.2018.07.006},
  pmid    = {30029164},
  url     = {https://doi.org/10.1016/j.redox.2018.07.006}
}

@article{kim2018-29988049,
  author  = {Kim, D. and Yoo, J. M. and Hwang, H. and Lee, J. and Lee, S. H. and Yun, S. P. and Park, M. J. and Lee, M. and others},
  title   = {{Graphene quantum dots prevent α-synucleinopathy in Parkinson's disease}},
  journal = {Nature nanotechnology},
  year    = {2018},
  doi     = {10.1038/s41565-018-0179-y},
  pmid    = {29988049},
  url     = {https://doi.org/10.1038/s41565-018-0179-y}
}

@article{temidoferreira2020-29950682,
  author  = {Temido-Ferreira, M. and Ferreira, D. G. and Batalha, V. L. and Marques-Morgado, I. and Coelho, J. E. and Pereira, P. and Gomes, R. and Pinto, A. and others},
  title   = {{Age-related shift in LTD is dependent on neuronal adenosine A2A receptors interplay with mGluR5 and NMDA receptors}},
  journal = {Molecular psychiatry},
  year    = {2020},
  doi     = {10.1038/s41380-018-0110-9},
  pmid    = {29950682},
  url     = {https://doi.org/10.1038/s41380-018-0110-9}
}

@article{hartmann2018-30456350,
  author  = {Hartmann, H. and Hornburg, D. and Czuppa, M. and Bader, J. and Michaelsen, M. and Farny, D. and Arzberger, T. and Mann, M. and others},
  title   = {{Proteomics and C9orf72 neuropathology identify ribosomes as poly-GR/PR interactors driving toxicity}},
  journal = {Life science alliance},
  year    = {2018},
  doi     = {10.26508/lsa.201800070},
  pmid    = {30456350},
  url     = {https://doi.org/10.26508/lsa.201800070}
}

@article{li2018-29747637,
  author  = {Li, J. Q. and Yuan, X. Z. and Li, H. Y. and Cao, X. P. and Yu, J. T. and Tan, L. and Chen, W. A. and {Alzheimer’s Disease Neuroimaging Initiative}},
  title   = {{Genome-wide association study identifies two loci influencing plasma neurofilament light levels}},
  journal = {BMC medical genomics},
  year    = {2018},
  doi     = {10.1186/s12920-018-0364-8},
  pmid    = {29747637},
  url     = {https://doi.org/10.1186/s12920-018-0364-8}
}

@article{peng2018-29743672,
  author  = {Peng, C. and Gathagan, R. J. and Covell, D. J. and Medellin, C. and Stieber, A. and Robinson, J. L. and Zhang, B. and Pitkin, R. M. and others},
  title   = {{Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathies}},
  journal = {Nature},
  year    = {2018},
  doi     = {10.1038/s41586-018-0104-4},
  pmid    = {29743672},
  url     = {https://doi.org/10.1038/s41586-018-0104-4}
}

@article{vargasrestrepo2018-29809330,
  author  = {Vargas-Restrepo, F. and Sabogal-Guáqueta, A. M. and Cardona-Gómez, G. P.},
  title   = {{[Quercetin ameliorates inflammation in CA1 hippocampal region in aged triple transgenic Alzheimer´s disease mice model.]}},
  journal = {Biomedica : revista del Instituto Nacional de Salud},
  year    = {2018},
  doi     = {10.7705/biomedica.v38i0.3761},
  pmid    = {29809330},
  url     = {https://doi.org/10.7705/biomedica.v38i0.3761}
}

@article{zhang2018-29628143,
  author  = {Zhang, K. and Daigle, J. G. and Cunningham, K. M. and Coyne, A. N. and Ruan, K. and Grima, J. C. and Bowen, K. E. and Wadhwa, H. and others},
  title   = {{Stress Granule Assembly Disrupts Nucleocytoplasmic Transport}},
  journal = {Cell},
  year    = {2018},
  doi     = {10.1016/j.cell.2018.03.025},
  pmid    = {29628143},
  url     = {https://doi.org/10.1016/j.cell.2018.03.025}
}

@article{qamar2018-29677515,
  author  = {Qamar, S. and Wang, G. and Randle, S. J. and Ruggeri, F. S. and Varela, J. A. and Lin, J. Q. and Phillips, E. C. and Miyashita, A. and others},
  title   = {{FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions}},
  journal = {Cell},
  year    = {2018},
  doi     = {10.1016/j.cell.2018.03.056},
  pmid    = {29677515},
  url     = {https://doi.org/10.1016/j.cell.2018.03.056}
}

@article{hofweber2018-29677514,
  author  = {Hofweber, M. and Hutten, S. and Bourgeois, B. and Spreitzer, E. and Niedner-Boblenz, A. and Schifferer, M. and Ruepp, M. D. and Simons, M. and others},
  title   = {{Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation}},
  journal = {Cell},
  year    = {2018},
  doi     = {10.1016/j.cell.2018.03.004},
  pmid    = {29677514},
  url     = {https://doi.org/10.1016/j.cell.2018.03.004}
}

@article{white2018-29556029,
  author  = {White, M. A. and Kim, E. and Duffy, A. and Adalbert, R. and Phillips, B. U. and Peters, O. M. and Stephenson, J. and Yang, S. and others},
  title   = {{TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD}},
  journal = {Nature neuroscience},
  year    = {2018},
  doi     = {10.1038/s41593-018-0113-5},
  pmid    = {29556029},
  url     = {https://doi.org/10.1038/s41593-018-0113-5}
}

@article{cochain2018-29545365,
  author  = {Cochain, C. and Vafadarnejad, E. and Arampatzi, P. and Pelisek, J. and Winkels, H. and Ley, K. and Wolf, D. and Saliba, A. E. and others},
  title   = {{Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis}},
  journal = {Circulation research},
  year    = {2018},
  doi     = {10.1161/circresaha.117.312509},
  pmid    = {29545365},
  url     = {https://doi.org/10.1161/circresaha.117.312509}
}

@article{ma2018-29501530,
  author  = {Ma, Q. L. and Teng, E. and Zuo, X. and Jones, M. and Teter, B. and Zhao, E. Y. and Zhu, C. and Bilousova, T. and others},
  title   = {{Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer's disease}},
  journal = {Neurobiology of disease},
  year    = {2018},
  doi     = {10.1016/j.nbd.2018.02.014},
  pmid    = {29501530},
  url     = {https://doi.org/10.1016/j.nbd.2018.02.014}
}

@article{li2018-29511089,
  author  = {Li, H. R. and Chiang, W. C. and Chou, P. C. and Wang, W. J. and Huang, JR.},
  title   = {{TAR DNA-binding protein 43 (TDP-43) liquid-liquid phase separation is mediated by just a few aromatic residues}},
  journal = {The Journal of biological chemistry},
  year    = {2018},
  doi     = {10.1074/jbc.ac117.001037},
  pmid    = {29511089},
  url     = {https://doi.org/10.1074/jbc.ac117.001037}
}

@article{rangaraju2018-29552013,
  author  = {Rangaraju, S. and Raza, S. A. and Li, N. X. and Betarbet, R. and Dammer, E. B. and Duong, D. and Lah, J. J. and Seyfried, N. T. and others},
  title   = {{Differential Phagocytic Properties of CD45low Microglia and CD45high Brain Mononuclear Phagocytes-Activation and Age-Related Effects}},
  journal = {Frontiers in immunology},
  year    = {2018},
  doi     = {10.3389/fimmu.2018.00405},
  pmid    = {29552013},
  url     = {https://doi.org/10.3389/fimmu.2018.00405}
}

@article{beckmann2018-29448957,
  author  = {Beckmann, N. and Giorgetti, E. and Neuhaus, A. and Zurbruegg, S. and Accart, N. and Smith, P. and Perdoux, J. and Perrot, L. and others},
  title   = {{Brain region-specific enhancement of remyelination and prevention of demyelination by the CSF1R kinase inhibitor BLZ945}},
  journal = {Acta neuropathologica communications},
  year    = {2018},
  doi     = {10.1186/s40478-018-0510-8},
  pmid    = {29448957},
  url     = {https://doi.org/10.1186/s40478-018-0510-8}
}

@article{groveman2018-29422107,
  author  = {Groveman, B. R. and Orrù, C. D. and Hughson, A. G. and Raymond, L. D. and Zanusso, G. and Ghetti, B. and Campbell, K. J. and Safar, J. and others},
  title   = {{Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC}},
  journal = {Acta neuropathologica communications},
  year    = {2018},
  doi     = {10.1186/s40478-018-0508-2},
  pmid    = {29422107},
  url     = {https://doi.org/10.1186/s40478-018-0508-2}
}

@article{shi2018-29400714,
  author  = {Shi, Y. and Lin, S. and Staats, K. A. and Li, Y. and Chang, W. H. and Hung, S. T. and Hendricks, E. and Linares, G. R. and others},
  title   = {{Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons}},
  journal = {Nature medicine},
  year    = {2018},
  doi     = {10.1038/nm.4490},
  pmid    = {29400714},
  url     = {https://doi.org/10.1038/nm.4490}
}

@article{guo2018-29398115,
  author  = {Guo, Q. and Lehmer, C. and Martínez-Sánchez, A. and Rudack, T. and Beck, F. and Hartmann, H. and Pérez-Berlanga, M. and Frottin, F. and others},
  title   = {{In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment}},
  journal = {Cell},
  year    = {2018},
  doi     = {10.1016/j.cell.2017.12.030},
  pmid    = {29398115},
  url     = {https://doi.org/10.1016/j.cell.2017.12.030}
}

@article{scott2018-29272357,
  author  = {Scott, G. and Zetterberg, H. and Jolly, A. and Cole, J. H. and De Simoni, S. and Jenkins, P. O. and Feeney, C. and Owen, D. R. and others},
  title   = {{Minocycline reduces chronic microglial activation after brain trauma but increases neurodegeneration}},
  journal = {Brain : a journal of neurology},
  year    = {2018},
  doi     = {10.1093/brain/awx339},
  pmid    = {29272357},
  url     = {https://doi.org/10.1093/brain/awx339}
}

@article{arrant2018-29378861,
  author  = {Arrant, A. E. and Onyilo, V. C. and Unger, D. E. and Roberson, E. D.},
  title   = {{Progranulin Gene Therapy Improves Lysosomal Dysfunction and Microglial Pathology Associated with Frontotemporal Dementia and Neuronal Ceroid Lipofuscinosis}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2018},
  doi     = {10.1523/jneurosci.3081-17.2018},
  pmid    = {29378861},
  url     = {https://doi.org/10.1523/jneurosci.3081-17.2018}
}

@article{ryan2018-29358076,
  author  = {Ryan, V. H. and Dignon, G. L. and Zerze, G. H. and Chabata, C. V. and Silva, R. and Conicella, A. E. and Amaya, J. and Burke, K. A. and others},
  title   = {{Mechanistic View of hnRNPA2 Low-Complexity Domain Structure, Interactions, and Phase Separation Altered by Mutation and Arginine Methylation}},
  journal = {Molecular cell},
  year    = {2018},
  doi     = {10.1016/j.molcel.2017.12.022},
  pmid    = {29358076},
  url     = {https://doi.org/10.1016/j.molcel.2017.12.022}
}

@article{chou2018-29311743,
  author  = {Chou, C. C. and Zhang, Y. and Umoh, M. E. and Vaughan, S. W. and Lorenzini, I. and Liu, F. and Sayegh, M. and Donlin-Asp, P. G. and others},
  title   = {{TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD}},
  journal = {Nature neuroscience},
  year    = {2018},
  doi     = {10.1038/s41593-017-0047-3},
  pmid    = {29311743},
  url     = {https://doi.org/10.1038/s41593-017-0047-3}
}

@article{goldberg2018-29316249,
  author  = {Goldberg, J. and Currais, A. and Prior, M. and Fischer, W. and Chiruta, C. and Ratliff, E. and Daugherty, D. and Dargusch, R. and others},
  title   = {{The mitochondrial ATP synthase is a shared drug target for aging and dementia}},
  journal = {Aging cell},
  year    = {2018},
  doi     = {10.1111/acel.12715},
  pmid    = {29316249},
  url     = {https://doi.org/10.1111/acel.12715}
}

@article{cui2018-28970251,
  author  = {Cui, G. H. and Wu, J. and Mou, F. F. and Xie, W. H. and Wang, F. B. and Wang, Q. L. and Fang, J. and Xu, Y. W. and others},
  title   = {{Exosomes derived from hypoxia-preconditioned mesenchymal stromal cells ameliorate cognitive decline by rescuing synaptic dysfunction and regulating inflammatory responses in APP/PS1 mice}},
  journal = {FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year    = {2018},
  doi     = {10.1096/fj.201700600r},
  pmid    = {28970251},
  url     = {https://doi.org/10.1096/fj.201700600r}
}

@article{simone2018-29113975,
  author  = {Simone, R. and Balendra, R. and Moens, T. G. and Preza, E. and Wilson, K. M. and Heslegrave, A. and Woodling, N. S. and Niccoli, T. and others},
  title   = {{G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo}},
  journal = {EMBO molecular medicine},
  year    = {2018},
  doi     = {10.15252/emmm.201707850},
  pmid    = {29113975},
  url     = {https://doi.org/10.15252/emmm.201707850}
}

@article{vicente2018-30124447,
  author  = {Vicente, M. C. and Almeida, M. C. and Bícego, K. C. and Carrettiero, D. C. and Gargaglioni, L. H.},
  title   = {{Hypercapnic and Hypoxic Respiratory Response During Wakefulness and Sleep in a Streptozotocin Model of Alzheimer's Disease in Rats}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2018},
  doi     = {10.3233/jad-180397},
  pmid    = {30124447},
  url     = {https://doi.org/10.3233/jad-180397}
}

@article{koch2018-29277405,
  author  = {Koch, G. and Bonnì, S. and Pellicciari, M. C. and Casula, E. P. and Mancini, M. and Esposito, R. and Ponzo, V. and Picazio, S. and others},
  title   = {{Transcranial magnetic stimulation of the precuneus enhances memory and neural activity in prodromal Alzheimer's disease}},
  journal = {NeuroImage},
  year    = {2018},
  doi     = {10.1016/j.neuroimage.2017.12.048},
  pmid    = {29277405},
  url     = {https://doi.org/10.1016/j.neuroimage.2017.12.048}
}

@article{rorabaugh2017-29053824,
  author  = {Rorabaugh, J. M. and Chalermpalanupap, T. and Botz-Zapp, C. A. and Fu, V. M. and Lembeck, N. A. and Cohen, R. M. and Weinshenker, D.},
  title   = {{Chemogenetic locus coeruleus activation restores reversal learning in a rat model of Alzheimer's disease}},
  journal = {Brain : a journal of neurology},
  year    = {2017},
  doi     = {10.1093/brain/awx232},
  pmid    = {29053824},
  url     = {https://doi.org/10.1093/brain/awx232}
}

@article{boros2017-28921611,
  author  = {Boros, B. D. and Greathouse, K. M. and Gentry, E. G. and Curtis, K. A. and Birchall, E. L. and Gearing, M. and Herskowitz, J. H.},
  title   = {{Dendritic spines provide cognitive resilience against Alzheimer's disease}},
  journal = {Annals of neurology},
  year    = {2017},
  doi     = {10.1002/ana.25049},
  pmid    = {28921611},
  url     = {https://doi.org/10.1002/ana.25049}
}

@article{tai2018-29050859,
  author  = {Tai, J. and Liu, W. and Li, Y. and Li, L. and Hölscher, C.},
  title   = {{Neuroprotective effects of a triple GLP-1/GIP/glucagon receptor agonist in the APP/PS1 transgenic mouse model of Alzheimer's disease}},
  journal = {Brain research},
  year    = {2018},
  doi     = {10.1016/j.brainres.2017.10.012},
  pmid    = {29050859},
  url     = {https://doi.org/10.1016/j.brainres.2017.10.012}
}

@article{ferreira2017-28945221,
  author  = {Ferreira, D. G. and Temido-Ferreira, M. and Vicente Miranda, H. and Batalha, V. L. and Coelho, J. E. and ÉM, Szegö and Marques-Morgado, I. and Vaz, S. H. and others},
  title   = {{α-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B}},
  journal = {Nature neuroscience},
  year    = {2017},
  doi     = {10.1038/nn.4648},
  pmid    = {28945221},
  url     = {https://doi.org/10.1038/nn.4648}
}

@article{casaletto2017-28939668,
  author  = {Casaletto, K. B. and Elahi, F. M. and Bettcher, B. M. and Neuhaus, J. and Bendlin, B. B. and Asthana, S. and Johnson, S. C. and Yaffe, K. and others},
  title   = {{Neurogranin, a synaptic protein, is associated with memory independent of Alzheimer biomarkers}},
  journal = {Neurology},
  year    = {2017},
  doi     = {10.1212/wnl.0000000000004569},
  pmid    = {28939668},
  url     = {https://doi.org/10.1212/wnl.0000000000004569}
}

@article{seo2017-28912154,
  author  = {Seo, J. and Kritskiy, O. and Watson, L. A. and Barker, S. J. and Dey, D. and Raja, W. K. and Lin, Y. T. and Ko, T. and others},
  title   = {{Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2017},
  doi     = {10.1523/jneurosci.0621-17.2017},
  pmid    = {28912154},
  url     = {https://doi.org/10.1523/jneurosci.0621-17.2017}
}

@article{spagnuolo2018-28923363,
  author  = {Spagnuolo, C. and Moccia, S. and Russo, G. L.},
  title   = {{Anti-inflammatory effects of flavonoids in neurodegenerative disorders}},
  journal = {European journal of medicinal chemistry},
  year    = {2018},
  doi     = {10.1016/j.ejmech.2017.09.001},
  pmid    = {28923363},
  url     = {https://doi.org/10.1016/j.ejmech.2017.09.001}
}

@article{karimi2017-28855224,
  author  = {Karimi, M. and Vedin, I. and Freund Levi, Y. and Basun, H. and Faxén Irving, G. and Eriksdotter, M. and Wahlund, L. O. and Schultzberg, M. and others},
  title   = {{DHA-rich n-3 fatty acid supplementation decreases DNA methylation in blood leukocytes: the OmegAD study}},
  journal = {The American journal of clinical nutrition},
  year    = {2017},
  doi     = {10.3945/ajcn.117.155648},
  pmid    = {28855224},
  url     = {https://doi.org/10.3945/ajcn.117.155648}
}

@article{monahan2017-28790177,
  author  = {Monahan, Z. and Ryan, V. H. and Janke, A. M. and Burke, K. A. and Rhoads, S. N. and Zerze, G. H. and O'Meally, R. and Dignon, G. L. and others},
  title   = {{Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity}},
  journal = {The EMBO journal},
  year    = {2017},
  doi     = {10.15252/embj.201696394},
  pmid    = {28790177},
  url     = {https://doi.org/10.15252/embj.201696394}
}

@article{choi2018-28775201,
  author  = {Choi, J. Y. and Cho, H. and Ahn, S. J. and Lee, J. H. and Ryu, Y. H. and Lee, M. S. and Lyoo, C. H.},
  title   = {{Off-Target 18F-AV-1451 Binding in the Basal Ganglia Correlates with Age-Related Iron Accumulation}},
  journal = {Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year    = {2018},
  doi     = {10.2967/jnumed.117.195248},
  pmid    = {28775201},
  url     = {https://doi.org/10.2967/jnumed.117.195248}
}

@article{mackenzie2017-28817800,
  author  = {Mackenzie, I. R. and Nicholson, A. M. and Sarkar, M. and Messing, J. and Purice, M. D. and Pottier, C. and Annu, K. and Baker, M. and others},
  title   = {{TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics}},
  journal = {Neuron},
  year    = {2017},
  doi     = {10.1016/j.neuron.2017.07.025},
  pmid    = {28817800},
  url     = {https://doi.org/10.1016/j.neuron.2017.07.025}
}

@article{lall2017-28737506,
  author  = {Lall, D. and Baloh, R. H.},
  title   = {{Microglia and C9orf72 in neuroinflammation and ALS and frontotemporal dementia}},
  journal = {The Journal of clinical investigation},
  year    = {2017},
  doi     = {10.1172/jci90607},
  pmid    = {28737506},
  url     = {https://doi.org/10.1172/jci90607}
}

@article{wang2018-28712011,
  author  = {Wang, Q. and Yuan, J. and Yu, Z. and Lin, L. and Jiang, Y. and Cao, Z. and Zhuang, P. and Whalen, M. J. and others},
  title   = {{FGF21 Attenuates High-Fat Diet-Induced Cognitive Impairment via Metabolic Regulation and Anti-inflammation of Obese Mice}},
  journal = {Molecular neurobiology},
  year    = {2018},
  doi     = {10.1007/s12035-017-0663-7},
  pmid    = {28712011},
  url     = {https://doi.org/10.1007/s12035-017-0663-7}
}

@article{afroz2017-28663553,
  author  = {Afroz, T. and Hock, E. M. and Ernst, P. and Foglieni, C. and Jambeau, M. and Gilhespy, L. A. B. and Laferriere, F. and Maniecka, Z. and others},
  title   = {{Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation}},
  journal = {Nature communications},
  year    = {2017},
  doi     = {10.1038/s41467-017-00062-0},
  pmid    = {28663553},
  url     = {https://doi.org/10.1038/s41467-017-00062-0}
}

@article{ladenbauer2017-28637840,
  author  = {Ladenbauer, J. and Külzow, N. and de Boor, R. and Avramova, E. and Grittner, U. and Flöel, A.},
  title   = {{Promoting Sleep Oscillations and Their Functional Coupling by Transcranial Stimulation Enhances Memory Consolidation in Mild Cognitive Impairment}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2017},
  doi     = {10.1523/jneurosci.0260-17.2017},
  pmid    = {28637840},
  url     = {https://doi.org/10.1523/jneurosci.0260-17.2017}
}

@article{alcolea2017-28592456,
  author  = {Alcolea, D. and Vilaplana, E. and Suárez-Calvet, M. and Illán-Gala, I. and Blesa, R. and Clarimón, J. and Lladó, A. and Sánchez-Valle, R. and others},
  title   = {{CSF sAPPβ, YKL-40, and neurofilament light in frontotemporal lobar degeneration}},
  journal = {Neurology},
  year    = {2017},
  doi     = {10.1212/wnl.0000000000004088},
  pmid    = {28592456},
  url     = {https://doi.org/10.1212/wnl.0000000000004088}
}

@article{wyatt2017-28601603,
  author  = {Wyatt, S. K. and Witt, T. and Barbaro, N. M. and Cohen-Gadol, A. A. and Brewster, A. L.},
  title   = {{Enhanced classical complement pathway activation and altered phagocytosis signaling molecules in human epilepsy}},
  journal = {Experimental neurology},
  year    = {2017},
  doi     = {10.1016/j.expneurol.2017.06.009},
  pmid    = {28601603},
  url     = {https://doi.org/10.1016/j.expneurol.2017.06.009}
}

@article{woo2017-28585542,
  author  = {Woo, J. A. and Liu, T. and Trotter, C. and Fang, C. C. and De Narvaez, E. and LePochat, P. and Maslar, D. and Bukhari, A. and others},
  title   = {{Loss of function CHCHD10 mutations in cytoplasmic TDP-43 accumulation and synaptic integrity}},
  journal = {Nature communications},
  year    = {2017},
  doi     = {10.1038/ncomms15558},
  pmid    = {28585542},
  url     = {https://doi.org/10.1038/ncomms15558}
}

@article{kim2017-28581123,
  author  = {Kim, J. H. and Ko, P. W. and Lee, H. W. and Jeong, J. Y. and Lee, M. G. and Lee, W. H. and Yu, R. and others},
  title   = {{Astrocyte-derived lipocalin-2 mediates hippocampal damage and cognitive deficits in experimental models of vascular dementia}},
  journal = {Glia},
  year    = {2017},
  doi     = {10.1002/glia.23174},
  pmid    = {28581123},
  url     = {https://doi.org/10.1002/glia.23174}
}

@article{halliday2017-28430857,
  author  = {Halliday, M. and Radford, H. and Zents, K. A. M. and Molloy, C. and Moreno, J. A. and Verity, N. C. and Smith, E. and Ortori, C. A. and others},
  title   = {{Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice}},
  journal = {Brain : a journal of neurology},
  year    = {2017},
  doi     = {10.1093/brain/awx074},
  pmid    = {28430857},
  url     = {https://doi.org/10.1093/brain/awx074}
}

@article{sompol2017-28559377,
  author  = {Sompol, P. and Furman, J. L. and Pleiss, M. M. and Kraner, S. D. and Artiushin, I. A. and Batten, SR. and Quintero, J. E. and Simmerman, L. A. and others},
  title   = {{Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2017},
  doi     = {10.1523/jneurosci.0877-17.2017},
  pmid    = {28559377},
  url     = {https://doi.org/10.1523/jneurosci.0877-17.2017}
}

@article{he2017-28579942,
  author  = {He, X. F. and Liu, D. X. and Zhang, Q. and Liang, F. Y. and Dai, G. Y. and Zeng, J. S. and Pei, Z. and Xu, G. Q. and others},
  title   = {{Voluntary Exercise Promotes Glymphatic Clearance of Amyloid Beta and Reduces the Activation of Astrocytes and Microglia in Aged Mice}},
  journal = {Frontiers in molecular neuroscience},
  year    = {2017},
  doi     = {10.3389/fnmol.2017.00144},
  pmid    = {28579942},
  url     = {https://doi.org/10.3389/fnmol.2017.00144}
}

@article{pinto2017-28567000,
  author  = {Pinto, S. and Cunha, C. and Barbosa, M. and Vaz, A. R. and Brites, D.},
  title   = {{Exosomes from NSC-34 Cells Transfected with hSOD1-G93A Are Enriched in miR-124 and Drive Alterations in Microglia Phenotype}},
  journal = {Frontiers in neuroscience},
  year    = {2017},
  doi     = {10.3389/fnins.2017.00273},
  pmid    = {28567000},
  url     = {https://doi.org/10.3389/fnins.2017.00273}
}

@article{kirkley2017-28476157,
  author  = {Kirkley, K. S. and Popichak, K. A. and Afzali, M. F. and Legare, M. E. and Tjalkens, R. B.},
  title   = {{Microglia amplify inflammatory activation of astrocytes in manganese neurotoxicity}},
  journal = {Journal of neuroinflammation},
  year    = {2017},
  doi     = {10.1186/s12974-017-0871-0},
  pmid    = {28476157},
  url     = {https://doi.org/10.1186/s12974-017-0871-0}
}

@article{becker2017-28405022,
  author  = {Becker, L. A. and Huang, B. and Bieri, G. and Ma, R. and Knowles, D. A. and Jafar-Nejad, P. and Messing, J. and Kim, H. J. and others},
  title   = {{Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice}},
  journal = {Nature},
  year    = {2017},
  doi     = {10.1038/nature22038},
  pmid    = {28405022},
  url     = {https://doi.org/10.1038/nature22038}
}

@article{errichelli2017-28358055,
  author  = {Errichelli, L. and Dini Modigliani, S. and Laneve, P. and Colantoni, A. and Legnini, I. and Capauto, D. and Rosa, A. and De Santis, R. and others},
  title   = {{FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons}},
  journal = {Nature communications},
  year    = {2017},
  doi     = {10.1038/ncomms14741},
  pmid    = {28358055},
  url     = {https://doi.org/10.1038/ncomms14741}
}

@article{shi2017-28342971,
  author  = {Shi, L. and Zhang, Z. and Li, L. and Hölscher, C.},
  title   = {{A novel dual GLP-1/GIP receptor agonist alleviates cognitive decline by re-sensitizing insulin signaling in the Alzheimer icv. STZ rat model}},
  journal = {Behavioural brain research},
  year    = {2017},
  doi     = {10.1016/j.bbr.2017.03.032},
  pmid    = {28342971},
  url     = {https://doi.org/10.1016/j.bbr.2017.03.032}
}

@article{zheng2017-28366226,
  author  = {Zheng, J. Y. and Sun, J. and Ji, C. M. and Shen, L. and Chen, Z. J. and Xie, P. and Sun, Y. Z. and Yu, R. T.},
  title   = {{Selective deletion of apolipoprotein E in astrocytes ameliorates the spatial learning and memory deficits in Alzheimer's disease (APP/PS1) mice by inhibiting TGF-β/Smad2/STAT3 signaling}},
  journal = {Neurobiology of aging},
  year    = {2017},
  doi     = {10.1016/j.neurobiolaging.2017.03.002},
  pmid    = {28366226},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2017.03.002}
}

@article{akiguchi2017-28261874,
  author  = {Akiguchi, I. and Pallàs, M. and Budka, H. and Akiyama, H. and Ueno, M. and Han, J. and Yagi, H. and Nishikawa, T. and others},
  title   = {{SAMP8 mice as a neuropathological model of accelerated brain aging and dementia: Toshio Takeda's legacy and future directions}},
  journal = {Neuropathology : official journal of the Japanese Society of Neuropathology},
  year    = {2017},
  doi     = {10.1111/neup.12373},
  pmid    = {28261874},
  url     = {https://doi.org/10.1111/neup.12373}
}

@article{wang2017-28318352,
  author  = {Wang, D. and Zhang, J. and Jiang, W. and Cao, Z. and Zhao, F. and Cai, T. and Aschner, M. and Luo, W.},
  title   = {{The role of NLRP3-CASP1 in inflammasome-mediated neuroinflammation and autophagy dysfunction in manganese-induced, hippocampal-dependent impairment of learning and memory ability}},
  journal = {Autophagy},
  year    = {2017},
  doi     = {10.1080/15548627.2017.1293766},
  pmid    = {28318352},
  url     = {https://doi.org/10.1080/15548627.2017.1293766}
}

@article{liu2017-28202389,
  author  = {Liu, D. and Tang, H. and Li, X. Y. and Deng, M. F. and Wei, N. and Wang, X. and Zhou, Y. F. and Wang, D. Q. and others},
  title   = {{Targeting the HDAC2/HNF-4A/miR-101b/AMPK Pathway Rescues Tauopathy and Dendritic Abnormalities in Alzheimer's Disease}},
  journal = {Molecular therapy : the journal of the American Society of Gene Therapy},
  year    = {2017},
  doi     = {10.1016/j.ymthe.2017.01.018},
  pmid    = {28202389},
  url     = {https://doi.org/10.1016/j.ymthe.2017.01.018}
}

@article{wang2017-28188218,
  author  = {Wang, M. and Ding, F. and Deng, S. and Guo, X. and Wang, W. and Iliff, J. J. and Nedergaard, M.},
  title   = {{Focal Solute Trapping and Global Glymphatic Pathway Impairment in a Murine Model of Multiple Microinfarcts}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2017},
  doi     = {10.1523/jneurosci.2112-16.2017},
  pmid    = {28188218},
  url     = {https://doi.org/10.1523/jneurosci.2112-16.2017}
}

@article{wong2017-28170377,
  author  = {Wong, Y. C. and Krainc, D.},
  title   = {{α-synuclein toxicity in neurodegeneration: mechanism and therapeutic strategies}},
  journal = {Nature medicine},
  year    = {2017},
  doi     = {10.1038/nm.4269},
  pmid    = {28170377},
  url     = {https://doi.org/10.1038/nm.4269}
}

@article{takahashi2017-28070672,
  author  = {Takahashi, H. and Klein, Z. A. and Bhagat, S. M. and Kaufman, A. C. and Kostylev, M. A. and Ikezu, T. and Strittmatter, S. M. and {Alzheimer’s Disease Neuroimaging Initiative}},
  title   = {{Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network}},
  journal = {Acta neuropathologica},
  year    = {2017},
  doi     = {10.1007/s00401-017-1668-z},
  pmid    = {28070672},
  url     = {https://doi.org/10.1007/s00401-017-1668-z}
}

@article{elhachem2017-28508374,
  author  = {El-Hachem, N. and Haibe-Kains, B. and Khalil, A. and Kobeissy, F. H. and Nemer, G.},
  title   = {{AutoDock and AutoDockTools for Protein-Ligand Docking: Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1(BACE1) as a Case Study}},
  journal = {Methods in molecular biology (Clifton, N.J.)},
  year    = {2017},
  doi     = {10.1007/978-1-4939-6952-4_20},
  pmid    = {28508374},
  url     = {https://doi.org/10.1007/978-1-4939-6952-4_20}
}

@article{liddelow2017-28099414,
  author  = {Liddelow, Shane A. and Guttenplan, Kevin A. and Clarke, Laura E. and Bennett, F. Chris and Bohlen, Christopher J. and Schirmer, Lucas and Bennett, Mariko L. and Münch, Alexandra E. and others},
  title   = {{Neurotoxic reactive astrocytes are induced by activated microglia}},
  journal = {Nature},
  year    = {2017},
  doi     = {10.1038/nature21029},
  pmid    = {28099414},
  url     = {https://doi.org/10.1038/nature21029}
}

@article{liu2017-28123022,
  author  = {Liu, Y. and Zhou, L. J. and Wang, J. and Li, D. and Ren, W. J. and Peng, J. and Wei, X. and others},
  title   = {{TNF-α Differentially Regulates Synaptic Plasticity in the Hippocampus and Spinal Cord by Microglia-Dependent Mechanisms after Peripheral Nerve Injury}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2017},
  doi     = {10.1523/jneurosci.2235-16.2016},
  pmid    = {28123022},
  url     = {https://doi.org/10.1523/jneurosci.2235-16.2016}
}

@article{liu2017-28003341,
  author  = {Liu, Q. and Chen, Y. and Shen, C. and Xiao, Y. and Wang, Y. and Liu, Z. and Liu, X.},
  title   = {{Chicoric acid supplementation prevents systemic inflammation-induced memory impairment and amyloidogenesis via inhibition of NF-κB}},
  journal = {FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year    = {2017},
  doi     = {10.1096/fj.201601071r},
  pmid    = {28003341},
  url     = {https://doi.org/10.1096/fj.201601071r}
}

@article{laurent2017-27818384,
  author  = {Laurent, C. and Dorothée, G. and Hunot, S. and Martin, E. and Monnet, Y. and Duchamp, M. and Dong, Y. and Légeron, F. P. and others},
  title   = {{Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy}},
  journal = {Brain : a journal of neurology},
  year    = {2017},
  doi     = {10.1093/brain/aww270},
  pmid    = {27818384},
  url     = {https://doi.org/10.1093/brain/aww270}
}

@article{bordi2016-27813694,
  author  = {Bordi, M. and Berg, M. J. and Mohan, P. S. and Peterhoff, C. M. and Alldred, M. J. and Che, S. and Ginsberg, S. D. and Nixon, R. A.},
  title   = {{Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy}},
  journal = {Autophagy},
  year    = {2016},
  doi     = {10.1080/15548627.2016.1239003},
  pmid    = {27813694},
  url     = {https://doi.org/10.1080/15548627.2016.1239003}
}

@article{kempf2016-27708245,
  author  = {Kempf, S. J. and Janik, D. and Barjaktarovic, Z. and Braga-Tanaka, I. and Tanaka, S. and Neff, F. and Saran, A. and Larsen, M. R. and others},
  title   = {{Chronic low-dose-rate ionising radiation affects the hippocampal phosphoproteome in the ApoE-/- Alzheimer's mouse model}},
  journal = {Oncotarget},
  year    = {2016},
  doi     = {10.18632/oncotarget.12376},
  pmid    = {27708245},
  url     = {https://doi.org/10.18632/oncotarget.12376}
}

@article{lorenzini2016-27775040,
  author  = {Lorenzini, L. and Giuliani, A. and Sivilia, S. and Baldassarro and Fernandez, M. and Lotti Margotti, M. and Giardino, L. and Fontani, V. and others},
  title   = {{REAC technology modifies pathological neuroinflammation and motor behaviour in an Alzheimer's disease mouse model}},
  journal = {Scientific reports},
  year    = {2016},
  doi     = {10.1038/srep35719},
  pmid    = {27775040},
  url     = {https://doi.org/10.1038/srep35719}
}

@article{imamura2016-27721502,
  author  = {Imamura, K. and Sahara, N. and Kanaan, N. M. and Tsukita, K. and Kondo, T. and Kutoku, Y. and Ohsawa, Y. and Sunada, Y. and others},
  title   = {{Calcium dysregulation contributes to neurodegeneration in FTLD patient iPSC-derived neurons}},
  journal = {Scientific reports},
  year    = {2016},
  doi     = {10.1038/srep34904},
  pmid    = {27721502},
  url     = {https://doi.org/10.1038/srep34904}
}

@article{ohrfelt2016-27716408,
  author  = {Öhrfelt, A. and Brinkmalm, A. and Dumurgier, J. and Brinkmalm, G. and Hansson, O. and Zetterberg, H. and Bouaziz-Amar, E. and Hugon, J. and others},
  title   = {{The pre-synaptic vesicle protein synaptotagmin is a novel biomarker for Alzheimer's disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2016},
  doi     = {10.1186/s13195-016-0208-8},
  pmid    = {27716408},
  url     = {https://doi.org/10.1186/s13195-016-0208-8}
}

@article{lee2016-27768896,
  author  = {Lee, K. H. and Zhang, P. and Kim, H. J. and Mitrea, D. M. and Sarkar, M. and Freibaum, B. D. and Cika, J. and Coughlin, M. and others},
  title   = {{C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles}},
  journal = {Cell},
  year    = {2016},
  doi     = {10.1016/j.cell.2016.10.002},
  pmid    = {27768896},
  url     = {https://doi.org/10.1016/j.cell.2016.10.002}
}

@article{lanedonovan2016-27683909,
  author  = {Lane-Donovan, C. and Wong, W. M. and Durakoglugil, M. S. and Wasser, C. R. and Jiang, S. and Xian, X. and Herz, J.},
  title   = {{Genetic Restoration of Plasma ApoE Improves Cognition and Partially Restores Synaptic Defects in ApoE-Deficient Mice}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2016},
  doi     = {10.1523/jneurosci.1054-16.2016},
  pmid    = {27683909},
  url     = {https://doi.org/10.1523/jneurosci.1054-16.2016}
}

@article{iguchi2016-27679482,
  author  = {Iguchi, Y. and Eid, L. and Parent, M. and Soucy, G. and Bareil, C. and Riku, Y. and Kawai, K. and Takagi, S. and others},
  title   = {{Exosome secretion is a key pathway for clearance of pathological TDP-43}},
  journal = {Brain : a journal of neurology},
  year    = {2016},
  doi     = {10.1093/brain/aww237},
  pmid    = {27679482},
  url     = {https://doi.org/10.1093/brain/aww237}
}

@article{goetzl2016-27601437,
  author  = {Goetzl, E. J. and Kapogiannis, D. and Schwartz, J. B. and Lobach, IV. and Goetzl, L. and Abner, E. L. and Jicha, G. A. and Karydas, A. M. and others},
  title   = {{Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer's disease}},
  journal = {FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year    = {2016},
  doi     = {10.1096/fj.201600816r},
  pmid    = {27601437},
  url     = {https://doi.org/10.1096/fj.201600816r}
}

@article{festoff2016-27553758,
  author  = {Festoff, B. W. and Sajja, R. K. and van Dreden, P. and Cucullo, L.},
  title   = {{HMGB1 and thrombin mediate the blood-brain barrier dysfunction acting as biomarkers of neuroinflammation and progression to neurodegeneration in Alzheimer's disease}},
  journal = {Journal of neuroinflammation},
  year    = {2016},
  doi     = {10.1186/s12974-016-0670-z},
  pmid    = {27553758},
  url     = {https://doi.org/10.1186/s12974-016-0670-z}
}

@article{lovelace2016-27540379,
  author  = {Lovelace, M. D. and Varney, B. and Sundaram, G. and Franco, N. F. and Ng, M. L. and Pai, S. and Lim, C. K. and Guillemin, G. J. and others},
  title   = {{Current Evidence for a Role of the Kynurenine Pathway of Tryptophan Metabolism in Multiple Sclerosis}},
  journal = {Frontiers in immunology},
  year    = {2016},
  doi     = {10.3389/fimmu.2016.00246},
  pmid    = {27540379},
  url     = {https://doi.org/10.3389/fimmu.2016.00246}
}

@article{kazim2016-27400746,
  author  = {Kazim, S. F. and Iqbal, K.},
  title   = {{Neurotrophic factor small-molecule mimetics mediated neuroregeneration and synaptic repair: emerging therapeutic modality for Alzheimer's disease}},
  journal = {Molecular neurodegeneration},
  year    = {2016},
  doi     = {10.1186/s13024-016-0119-y},
  pmid    = {27400746},
  url     = {https://doi.org/10.1186/s13024-016-0119-y}
}

@article{tavakol2017-27389777,
  author  = {Tavakol, S. and Musavi, S. M. M. and Tavakol, B. and Hoveizi, E. and Ai, J. and Rezayat, S. M.},
  title   = {{Noggin Along with a Self-Assembling Peptide Nanofiber Containing Long Motif of Laminin Induces Tyrosine Hydroxylase Gene Expression}},
  journal = {Molecular neurobiology},
  year    = {2017},
  doi     = {10.1007/s12035-016-0006-0},
  pmid    = {27389777},
  url     = {https://doi.org/10.1007/s12035-016-0006-0}
}

@article{henderson2016-27246255,
  author  = {Henderson, B. W. and Gentry, E. G. and Rush, T. and Troncoso, J. C. and Thambisetty, M. and Montine, T. J. and Herskowitz, J. H.},
  title   = {{Rho-associated protein kinase 1 (ROCK1) is increased in Alzheimer's disease and ROCK1 depletion reduces amyloid-β levels in brain}},
  journal = {Journal of neurochemistry},
  year    = {2016},
  doi     = {10.1111/jnc.13688},
  pmid    = {27246255},
  url     = {https://doi.org/10.1111/jnc.13688}
}

@article{tsai2016-27318702,
  author  = {Tsai, H. C. and Han, M. H.},
  title   = {{Sphingosine-1-Phosphate (S1P) and S1P Signaling Pathway: Therapeutic Targets in Autoimmunity and Inflammation}},
  journal = {Drugs},
  year    = {2016},
  doi     = {10.1007/s40265-016-0603-2},
  pmid    = {27318702},
  url     = {https://doi.org/10.1007/s40265-016-0603-2}
}

@article{wang2016-27348499,
  author  = {Wang, W. and Wang, L. and Lu, J. and Siedlak, S. L. and Fujioka, H. and Liang, J. and Jiang, S. and Ma, X. and others},
  title   = {{The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity}},
  journal = {Nature medicine},
  year    = {2016},
  doi     = {10.1038/nm.4130},
  pmid    = {27348499},
  url     = {https://doi.org/10.1038/nm.4130}
}

@article{dorard2016-27460148,
  author  = {Dorard, E. and Gorisse-Hussonnois, L. and Guihenneuc-Jouyaux, C. and Albac, C. and Potier, M. C. and Allinquant, B.},
  title   = {{Increases of SET level and translocation are correlated with tau hyperphosphorylation at ser202/thr205 in CA1 of Ts65Dn mice}},
  journal = {Neurobiology of aging},
  year    = {2016},
  doi     = {10.1016/j.neurobiolaging.2016.06.010},
  pmid    = {27460148},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2016.06.010}
}

@article{webster2016-27334615,
  author  = {Webster, C. P. and Smith, E. F. and Bauer, C. S. and Moller, A. and Hautbergue, G. M. and Ferraiuolo, L. and Myszczynska, M. A. and Higginbottom, A. and others},
  title   = {{The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy}},
  journal = {The EMBO journal},
  year    = {2016},
  doi     = {10.15252/embj.201694401},
  pmid    = {27334615},
  url     = {https://doi.org/10.15252/embj.201694401}
}

@article{ratti2016-27015757,
  author  = {Ratti, A. and Buratti, E.},
  title   = {{Physiological functions and pathobiology of TDP-43 and FUS/TLS proteins}},
  journal = {Journal of neurochemistry},
  year    = {2016},
  doi     = {10.1111/jnc.13625},
  pmid    = {27015757},
  url     = {https://doi.org/10.1111/jnc.13625}
}

@article{ahmad2016-27211305,
  author  = {Ahmad, L. and Zhang, S. Y. and Casanova, J. L. and Sancho-Shimizu, V.},
  title   = {{Human TBK1: A Gatekeeper of Neuroinflammation}},
  journal = {Trends in molecular medicine},
  year    = {2016},
  doi     = {10.1016/j.molmed.2016.04.006},
  pmid    = {27211305},
  url     = {https://doi.org/10.1016/j.molmed.2016.04.006}
}

@article{osorio2016-26951396,
  author  = {Osorio, R. S. and Ducca, E. L. and Wohlleber, M. E. and Tanzi, E. B. and Gumb, T. and Twumasi, A. and Tweardy, S. and Lewis, C. and others},
  title   = {{Orexin-A is Associated with Increases in Cerebrospinal Fluid Phosphorylated-Tau in Cognitively Normal Elderly Subjects}},
  journal = {Sleep},
  year    = {2016},
  doi     = {10.5665/sleep.5846},
  pmid    = {26951396},
  url     = {https://doi.org/10.5665/sleep.5846}
}

@article{beckmann2016-27459925,
  author  = {Beckmann, N. and Doelemeyer, A. and Zurbruegg, S. and Bigot, K. and Theil, D. and Frieauff, W. and Kolly, C. and Moulin, P. and others},
  title   = {{Longitudinal noninvasive magnetic resonance imaging of brain microhemorrhages in BACE inhibitor-treated APP transgenic mice}},
  journal = {Neurobiology of aging},
  year    = {2016},
  doi     = {10.1016/j.neurobiolaging.2016.05.009},
  pmid    = {27459925},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2016.05.009}
}

@article{miyagawa2016-27179792,
  author  = {Miyagawa, T. and Ebinuma, I. and Morohashi, Y. and Hori, Y. and Young Chang, M. and Hattori, H. and Maehara, T. and Yokoshima, S. and others},
  title   = {{BIN1 regulates BACE1 intracellular trafficking and amyloid-β production}},
  journal = {Human molecular genetics},
  year    = {2016},
  doi     = {10.1093/hmg/ddw146},
  pmid    = {27179792},
  url     = {https://doi.org/10.1093/hmg/ddw146}
}

@article{saber2017-26976047,
  author  = {Saber, M. and Kokiko-Cochran, O. and Puntambekar, S. S. and Lathia, J. D. and Lamb, B. T.},
  title   = {{Triggering Receptor Expressed on Myeloid Cells 2 Deficiency Alters Acute Macrophage Distribution and Improves Recovery after Traumatic Brain Injury}},
  journal = {Journal of neurotrauma},
  year    = {2017},
  doi     = {10.1089/neu.2016.4401},
  pmid    = {26976047},
  url     = {https://doi.org/10.1089/neu.2016.4401}
}

@article{nakano2016-27102354,
  author  = {Nakano, M. and Nagaishi, K. and Konari, N. and Saito, Y. and Chikenji, T. and Mizue, Y. and Fujimiya, M.},
  title   = {{Bone marrow-derived mesenchymal stem cells improve diabetes-induced cognitive impairment by exosome transfer into damaged neurons and astrocytes}},
  journal = {Scientific reports},
  year    = {2016},
  doi     = {10.1038/srep24805},
  pmid    = {27102354},
  url     = {https://doi.org/10.1038/srep24805}
}

@article{jiang2016-27112497,
  author  = {Jiang, J. and Zhu, Q. and Gendron, T. F. and Saberi, S. and McAlonis-Downes, M. and Seelman, A. and Stauffer, J. E. and Jafar-Nejad, P. and others},
  title   = {{Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs}},
  journal = {Neuron},
  year    = {2016},
  doi     = {10.1016/j.neuron.2016.04.006},
  pmid    = {27112497},
  url     = {https://doi.org/10.1016/j.neuron.2016.04.006}
}

@article{sellier2016-27103069,
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  title   = {{Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death}},
  journal = {The EMBO journal},
  year    = {2016},
  doi     = {10.15252/embj.201593350},
  pmid    = {27103069},
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}

@article{lui2016-27114033,
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  title   = {{Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation}},
  journal = {Cell},
  year    = {2016},
  doi     = {10.1016/j.cell.2016.04.001},
  pmid    = {27114033},
  url     = {https://doi.org/10.1016/j.cell.2016.04.001}
}

@article{daschil2016-27092076,
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  title   = {{Green-Fluorescent Protein(+) Astrocytes Attach to Beta-Amyloid Plaques in an Alzheimer Mouse Model and Are Sensitive for Clasmatodendrosis}},
  journal = {Frontiers in aging neuroscience},
  year    = {2016},
  doi     = {10.3389/fnagi.2016.00075},
  pmid    = {27092076},
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}

@article{lineback2016-a0ddd430,
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  title   = {{Dopa-responsive akinesia: Homozygous GCH1 mutation (P5.150)}},
  journal = {Neurology},
  year    = {2016},
  doi     = {10.1212/wnl.86.16_supplement.p5.150},
  url     = {https://doi.org/10.1212/wnl.86.16_supplement.p5.150}
}

@article{hong2016-27033548,
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  title   = {{Complement and microglia mediate early synapse loss in Alzheimer mouse models}},
  journal = {Science (New York, N.Y.)},
  year    = {2016},
  doi     = {10.1126/science.aad8373},
  pmid    = {27033548},
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}

@article{zhang2016-26998601,
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  title   = {{C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins}},
  journal = {Nature neuroscience},
  year    = {2016},
  doi     = {10.1038/nn.4272},
  pmid    = {26998601},
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}

@article{mohle2016-26984535,
  author  = {Möhle, L. and Israel, N. and Paarmann, K. and Krohn, M. and Pietkiewicz, S. and Müller, A. and Lavrik, I. N. and Buguliskis, J. S. and others},
  title   = {{Chronic Toxoplasma gondii infection enhances β-amyloid phagocytosis and clearance by recruited monocytes}},
  journal = {Acta neuropathologica communications},
  year    = {2016},
  doi     = {10.1186/s40478-016-0293-8},
  pmid    = {26984535},
  url     = {https://doi.org/10.1186/s40478-016-0293-8}
}

@article{lovelace2017-26995730,
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  title   = {{Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases}},
  journal = {Neuropharmacology},
  year    = {2017},
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  pmid    = {26995730},
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}

@article{orourke2016-26989253,
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  title   = {{C9orf72 is required for proper macrophage and microglial function in mice}},
  journal = {Science (New York, N.Y.)},
  year    = {2016},
  doi     = {10.1126/science.aaf1064},
  pmid    = {26989253},
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}

@article{hwang2016-26910914,
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  title   = {{CCR5 deficiency accelerates lipopolysaccharide-induced astrogliosis, amyloid-beta deposit and impaired memory function}},
  journal = {Oncotarget},
  year    = {2016},
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  pmid    = {26910914},
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}

@article{lesage2016-26942284,
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  title   = {{Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy}},
  journal = {American journal of human genetics},
  year    = {2016},
  doi     = {10.1016/j.ajhg.2016.01.014},
  pmid    = {26942284},
  url     = {https://doi.org/10.1016/j.ajhg.2016.01.014}
}

@article{sydow2016-26916334,
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  title   = {{Age-dependent neuroinflammation and cognitive decline in a novel Ala152Thr-Tau transgenic mouse model of PSP and AD}},
  journal = {Acta neuropathologica communications},
  year    = {2016},
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  pmid    = {26916334},
  url     = {https://doi.org/10.1186/s40478-016-0281-z}
}

@article{graham2016-26888450,
  author  = {Graham, L. C. and Harder, J. M. and Soto, I. and de Vries, W. N. and John, S. W. and Howell, G. R.},
  title   = {{Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer's disease}},
  journal = {Scientific reports},
  year    = {2016},
  doi     = {10.1038/srep21568},
  pmid    = {26888450},
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}

@article{brendel2016-26912428,
  author  = {Brendel, M. and Probst, F. and Jaworska, A. and Overhoff, F. and Korzhova, V. and Albert, N. L. and Beck, R. and Lindner, S. and others},
  title   = {{Glial Activation and Glucose Metabolism in a Transgenic Amyloid Mouse Model: A Triple-Tracer PET Study}},
  journal = {Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year    = {2016},
  doi     = {10.2967/jnumed.115.167858},
  pmid    = {26912428},
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}

@article{barini2016-26858121,
  author  = {Barini, E. and Antico, O. and Zhao, Y. and Asta, F. and Tucci, V. and Catelani, T. and Marotta, R. and Xu, H. and others},
  title   = {{Metformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathy}},
  journal = {Molecular neurodegeneration},
  year    = {2016},
  doi     = {10.1186/s13024-016-0082-7},
  pmid    = {26858121},
  url     = {https://doi.org/10.1186/s13024-016-0082-7}
}

@article{booth2016-26758828,
  author  = {Booth, C. A. and Witton, J. and Nowacki, J. and Tsaneva-Atanasova, K. and Jones, M. W. and Randall, A. D. and Brown, J. T.},
  title   = {{Altered Intrinsic Pyramidal Neuron Properties and Pathway-Specific Synaptic Dysfunction Underlie Aberrant Hippocampal Network Function in a Mouse Model of Tauopathy}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2016},
  doi     = {10.1523/jneurosci.2151-15.2016},
  pmid    = {26758828},
  url     = {https://doi.org/10.1523/jneurosci.2151-15.2016}
}

@article{leszek2016-26831258,
  author  = {Leszek, J. and Barreto, G. E. and Gąsiorowski, K. and Koutsouraki, E. and Ávila-Rodrigues, M. and Aliev, G.},
  title   = {{Inflammatory Mechanisms and Oxidative Stress as Key Factors Responsible for Progression of Neurodegeneration: Role of Brain Innate Immune System}},
  journal = {CNS \& neurological disorders drug targets},
  year    = {2016},
  doi     = {10.2174/1871527315666160202125914},
  pmid    = {26831258},
  url     = {https://doi.org/10.2174/1871527315666160202125914}
}

@article{catorce2016-26639457,
  author  = {Catorce, M. N. and Gevorkian, G.},
  title   = {{LPS-induced Murine Neuroinflammation Model: Main Features and Suitability for Pre-clinical Assessment of Nutraceuticals}},
  journal = {Current neuropharmacology},
  year    = {2016},
  doi     = {10.2174/1570159x14666151204122017},
  pmid    = {26639457},
  url     = {https://doi.org/10.2174/1570159x14666151204122017}
}

@article{hellwig2015-26698298,
  author  = {Hellwig, K. and Kvartsberg, H. and Portelius, E. and Andreasson, U. and Oberstein, T. J. and Lewczuk, P. and Blennow, K. and Kornhuber, J. and others},
  title   = {{Neurogranin and YKL-40: independent markers of synaptic degeneration and neuroinflammation in Alzheimer's disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2015},
  doi     = {10.1186/s13195-015-0161-y},
  pmid    = {26698298},
  url     = {https://doi.org/10.1186/s13195-015-0161-y}
}

@article{walter2016-26694609,
  author  = {Walter, J.},
  title   = {{The Triggering Receptor Expressed on Myeloid Cells 2: A Molecular Link of Neuroinflammation and Neurodegenerative Diseases}},
  journal = {The Journal of biological chemistry},
  year    = {2016},
  doi     = {10.1074/jbc.r115.704981},
  pmid    = {26694609},
  url     = {https://doi.org/10.1074/jbc.r115.704981}
}

@article{zempel2015-26691836,
  author  = {Zempel, H. and Mandelkow, E. M.},
  title   = {{Tau missorting and spastin-induced microtubule disruption in neurodegeneration: Alzheimer Disease and Hereditary Spastic Paraplegia}},
  journal = {Molecular neurodegeneration},
  year    = {2015},
  doi     = {10.1186/s13024-015-0064-1},
  pmid    = {26691836},
  url     = {https://doi.org/10.1186/s13024-015-0064-1}
}

@article{schnoder2016-26663083,
  author  = {Schnöder, L. and Hao, W. and Qin, Y. and Liu, S. and Tomic, I. and Liu, X. and Fassbender, K. and Liu, Y.},
  title   = {{Deficiency of Neuronal p38α MAPK Attenuates Amyloid Pathology in Alzheimer Disease Mouse and Cell Models through Facilitating Lysosomal Degradation of BACE1}},
  journal = {The Journal of biological chemistry},
  year    = {2016},
  doi     = {10.1074/jbc.m115.695916},
  pmid    = {26663083},
  url     = {https://doi.org/10.1074/jbc.m115.695916}
}

@article{schmidburgk2016-26553871,
  author  = {Schmid-Burgk, J. L. and Chauhan, D. and Schmidt, T. and Ebert, T. S. and Reinhardt, J. and Endl, E. and Hornung, V.},
  title   = {{A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation}},
  journal = {The Journal of biological chemistry},
  year    = {2016},
  doi     = {10.1074/jbc.c115.700492},
  pmid    = {26553871},
  url     = {https://doi.org/10.1074/jbc.c115.700492}
}

@article{siman2015-26540269,
  author  = {Siman, R. and Cocca, R. and Dong, Y.},
  title   = {{The mTOR Inhibitor Rapamycin Mitigates Perforant Pathway Neurodegeneration and Synapse Loss in a Mouse Model of Early-Stage Alzheimer-Type Tauopathy}},
  journal = {PloS one},
  year    = {2015},
  doi     = {10.1371/journal.pone.0142340},
  pmid    = {26540269},
  url     = {https://doi.org/10.1371/journal.pone.0142340}
}

@article{saftig2015-26522965,
  author  = {Saftig, P. and Lichtenthaler, S. F.},
  title   = {{The alpha secretase ADAM10: A metalloprotease with multiple functions in the brain}},
  journal = {Progress in neurobiology},
  year    = {2015},
  doi     = {10.1016/j.pneurobio.2015.10.003},
  pmid    = {26522965},
  url     = {https://doi.org/10.1016/j.pneurobio.2015.10.003}
}

@article{aulas2015-26557057,
  author  = {Aulas, A. and Vande Velde, C.},
  title   = {{Alterations in stress granule dynamics driven by TDP-43 and FUS: a link to pathological inclusions in ALS?}},
  journal = {Frontiers in cellular neuroscience},
  year    = {2015},
  doi     = {10.3389/fncel.2015.00423},
  pmid    = {26557057},
  url     = {https://doi.org/10.3389/fncel.2015.00423}
}

@article{morgan2015-26483679,
  author  = {Morgan, T. E. and Finch, C. E.},
  title   = {{Astrocytic estrogen receptors and impaired neurotrophic responses in a rat model of perimenopause}},
  journal = {Frontiers in aging neuroscience},
  year    = {2015},
  doi     = {10.3389/fnagi.2015.00179},
  pmid    = {26483679},
  url     = {https://doi.org/10.3389/fnagi.2015.00179}
}

@article{bailey2015-26374897,
  author  = {Bailey, C. C. and DeVaux, L. B. and Farzan, M.},
  title   = {{The Triggering Receptor Expressed on Myeloid Cells 2 Binds Apolipoprotein E}},
  journal = {The Journal of biological chemistry},
  year    = {2015},
  doi     = {10.1074/jbc.m115.677286},
  pmid    = {26374897},
  url     = {https://doi.org/10.1074/jbc.m115.677286}
}

@article{slevin2015-26335098,
  author  = {Slevin, M. and Matou, S. and Zeinolabediny, Y. and Corpas, R. and Weston, R. and Liu, D. and Boras, E. and Di Napoli, M. and others},
  title   = {{Monomeric C-reactive protein--a key molecule driving development of Alzheimer's disease associated with brain ischaemia?}},
  journal = {Scientific reports},
  year    = {2015},
  doi     = {10.1038/srep13281},
  pmid    = {26335098},
  url     = {https://doi.org/10.1038/srep13281}
}

@article{jovicic2015-26308983,
  author  = {Jovičić, A. and Mertens, J. and Boeynaems, S. and Bogaert, E. and Chai, N. and Yamada, S. B. and Paul, J. W. and Sun, S. and others},
  title   = {{Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS}},
  journal = {Nature neuroscience},
  year    = {2015},
  doi     = {10.1038/nn.4085},
  pmid    = {26308983},
  url     = {https://doi.org/10.1038/nn.4085}
}

@article{molliex2015-26406374,
  author  = {Molliex, A. and Temirov, J. and Lee, J. and Coughlin, M. and Kanagaraj, A. P. and Kim, H. J. and Mittag, T. and Taylor, J. P.},
  title   = {{Phase separation by low complexity domains promotes stress granule assembly and drives pathological fibrillization}},
  journal = {Cell},
  year    = {2015},
  doi     = {10.1016/j.cell.2015.09.015},
  pmid    = {26406374},
  url     = {https://doi.org/10.1016/j.cell.2015.09.015}
}

@article{lucassen2015-26330520,
  author  = {Lucassen, P. J. and Oomen, C. A. and Naninck, E. F. and Fitzsimons, C. P. and van Dam, A. M. and Czeh, B. and Korosi, A.},
  title   = {{Regulation of Adult Neurogenesis and Plasticity by (Early) Stress, Glucocorticoids, and Inflammation}},
  journal = {Cold Spring Harbor perspectives in biology},
  year    = {2015},
  doi     = {10.1101/cshperspect.a021303},
  pmid    = {26330520},
  url     = {https://doi.org/10.1101/cshperspect.a021303}
}

@article{willem2015-26322584,
  author  = {Willem, M. and Tahirovic, S. and Busche, M. A. and Ovsepian, S. V. and Chafai, M. and Kootar, S. and Hornburg, D. and Evans, L. D. and others},
  title   = {{η-Secretase processing of APP inhibits neuronal activity in the hippocampus}},
  journal = {Nature},
  year    = {2015},
  doi     = {10.1038/nature14864},
  pmid    = {26322584},
  url     = {https://doi.org/10.1038/nature14864}
}

@article{freibaum2015-26308899,
  author  = {Freibaum, B. D. and Lu, Y. and Lopez-Gonzalez, R. and Kim, N. C. and Almeida, S. and Lee, K. H. and Badders, N. and Valentine, M. and others},
  title   = {{GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport}},
  journal = {Nature},
  year    = {2015},
  doi     = {10.1038/nature14974},
  pmid    = {26308899},
  url     = {https://doi.org/10.1038/nature14974}
}

@article{zhang2015-26308891,
  author  = {Zhang, K. and Donnelly, C. J. and Haeusler, A. R. and Grima, J. C. and Machamer, J. B. and Steinwald, P. and Daley, E. L. and Miller, S. J. and others},
  title   = {{The C9orf72 repeat expansion disrupts nucleocytoplasmic transport}},
  journal = {Nature},
  year    = {2015},
  doi     = {10.1038/nature14973},
  pmid    = {26308891},
  url     = {https://doi.org/10.1038/nature14973}
}

@article{ling2015-26250685,
  author  = {Ling, J. P. and Pletnikova, O. and Troncoso, J. C. and Wong, P. C.},
  title   = {{TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD}},
  journal = {Science (New York, N.Y.)},
  year    = {2015},
  doi     = {10.1126/science.aab0983},
  pmid    = {26250685},
  url     = {https://doi.org/10.1126/science.aab0983}
}

@article{egea2015-26232730,
  author  = {Egea, J. and Buendia, I. and Parada, E. and Navarro, E. and León, R. and Lopez, M. G.},
  title   = {{Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection}},
  journal = {Biochemical pharmacology},
  year    = {2015},
  doi     = {10.1016/j.bcp.2015.07.032},
  pmid    = {26232730},
  url     = {https://doi.org/10.1016/j.bcp.2015.07.032}
}

@article{rocha2015-26094487,
  author  = {Rocha, E. M. and Smith, G. A. and Park, E. and Cao, H. and Graham, A. R. and Brown, E. and McLean, JR. and Hayes, M. A. and others},
  title   = {{Sustained Systemic Glucocerebrosidase Inhibition Induces Brain α-Synuclein Aggregation, Microglia and Complement C1q Activation in Mice}},
  journal = {Antioxidants \& redox signaling},
  year    = {2015},
  doi     = {10.1089/ars.2015.6307},
  pmid    = {26094487},
  url     = {https://doi.org/10.1089/ars.2015.6307}
}

@article{kim2015-29854930,
  author  = {Kim, H. J. and Seo, S. W. and Chang, J. W. and Lee, J. I. and Kim, C. H. and Chin, J. and Choi, S. J. and Kwon, H. and others},
  title   = {{Stereotactic brain injection of human umbilical cord blood mesenchymal stem cells in patients with Alzheimer's disease dementia: A phase 1 clinical trial}},
  journal = {Alzheimer's \& dementia (New York, N. Y.)},
  year    = {2015},
  doi     = {10.1016/j.trci.2015.06.007},
  pmid    = {29854930},
  url     = {https://doi.org/10.1016/j.trci.2015.06.007}
}

@article{skerrett2015-26163517,
  author  = {Skerrett, R. and Pellegrino, M. P. and Casali, B. T. and Taraboanta, L. and Landreth, G. E.},
  title   = {{Combined Liver X Receptor/Peroxisome Proliferator-activated Receptor γ Agonist Treatment Reduces Amyloid β Levels and Improves Behavior in Amyloid Precursor Protein/Presenilin 1 Mice}},
  journal = {The Journal of biological chemistry},
  year    = {2015},
  doi     = {10.1074/jbc.m115.652008},
  pmid    = {26163517},
  url     = {https://doi.org/10.1074/jbc.m115.652008}
}

@article{birnbaum2015-26086964,
  author  = {Birnbaum, J. H. and Bali, J. and Rajendran, L. and Nitsch, R. M. and Tackenberg, C.},
  title   = {{Calcium flux-independent NMDA receptor activity is required for Aβ oligomer-induced synaptic loss}},
  journal = {Cell death \& disease},
  year    = {2015},
  doi     = {10.1038/cddis.2015.160},
  pmid    = {26086964},
  url     = {https://doi.org/10.1038/cddis.2015.160}
}

@article{paumier2015-26093169,
  author  = {Paumier, K. L. and Luk, K. C. and Manfredsson, F. P. and Kanaan, N. M. and Lipton, J. W. and Collier, T. J. and Steece-Collier, K. and Kemp, C. J. and others},
  title   = {{Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration}},
  journal = {Neurobiology of disease},
  year    = {2015},
  doi     = {10.1016/j.nbd.2015.06.003},
  pmid    = {26093169},
  url     = {https://doi.org/10.1016/j.nbd.2015.06.003}
}

@article{sephton2015-26047658,
  author  = {Sephton, C. F. and Yu, G.},
  title   = {{The function of RNA-binding proteins at the synapse: implications for neurodegeneration}},
  journal = {Cellular and molecular life sciences : CMLS},
  year    = {2015},
  doi     = {10.1007/s00018-015-1943-x},
  pmid    = {26047658},
  url     = {https://doi.org/10.1007/s00018-015-1943-x}
}

@article{calderongarciduenas2015-26037109,
  author  = {Calderón-Garcidueñas, L. and Franco-Lira, M. and D'Angiulli, A. and Rodríguez-Díaz, J. and Blaurock-Busch, E. and Busch, Y. and Chao, C. K. and Thompson, C. and others},
  title   = {{Mexico City normal weight children exposed to high concentrations of ambient PM2.5 show high blood leptin and endothelin-1, vitamin D deficiency, and food reward hormone dysregulation versus low pollution controls. Relevance for obesity and Alzheimer disease}},
  journal = {Environmental research},
  year    = {2015},
  doi     = {10.1016/j.envres.2015.05.012},
  pmid    = {26037109},
  url     = {https://doi.org/10.1016/j.envres.2015.05.012}
}

@article{chew2015-25977373,
  author  = {Chew, J. and Gendron, T. F. and Prudencio, M. and Sasaguri, H. and Zhang, Y. J. and Castanedes-Casey, M. and Lee, C. W. and Jansen-West, K. and others},
  title   = {{Neurodegeneration. C9ORF72 repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits}},
  journal = {Science (New York, N.Y.)},
  year    = {2015},
  doi     = {10.1126/science.aaa9344},
  pmid    = {25977373},
  url     = {https://doi.org/10.1126/science.aaa9344}
}

@article{michailidou2015-25727254,
  author  = {Michailidou, I. and Willems, J. G. and Kooi, E. J. and van Eden, C. and Gold, S. M. and Geurts, J. J. and Baas, F. and Huitinga, I. and others},
  title   = {{Complement C1q-C3-associated synaptic changes in multiple sclerosis hippocampus}},
  journal = {Annals of neurology},
  year    = {2015},
  doi     = {10.1002/ana.24398},
  pmid    = {25727254},
  url     = {https://doi.org/10.1002/ana.24398}
}

@article{jin2015-25918155,
  author  = {Jin, N. and Yin, X. and Gu, J. and Zhang, X. and Shi, J. and Qian, W. and Ji, Y. and Cao, M. and others},
  title   = {{Truncation and Activation of Dual Specificity Tyrosine Phosphorylation-regulated Kinase 1A by Calpain I: A MOLECULAR MECHANISM LINKED TO TAU PATHOLOGY IN ALZHEIMER DISEASE}},
  journal = {The Journal of biological chemistry},
  year    = {2015},
  doi     = {10.1074/jbc.m115.645507},
  pmid    = {25918155},
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}

@article{fan2015-25840980,
  author  = {Fan, Z. and Harold, D. and Pasqualetti, G. and Williams, J. and Brooks, D. J. and Edison, P.},
  title   = {{Can Studies of Neuroinflammation in a TSPO Genetic Subgroup (HAB or MAB) Be Applied to the Entire AD Cohort?}},
  journal = {Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year    = {2015},
  doi     = {10.2967/jnumed.114.149443},
  pmid    = {25840980},
  url     = {https://doi.org/10.2967/jnumed.114.149443}
}

@article{scotter2015-25652699,
  author  = {Scotter, E. L. and Chen, H. J. and Shaw, C. E.},
  title   = {{TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets}},
  journal = {Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics},
  year    = {2015},
  doi     = {10.1007/s13311-015-0338-x},
  pmid    = {25652699},
  url     = {https://doi.org/10.1007/s13311-015-0338-x}
}

@article{kaufman2015-25707991,
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  title   = {{Fyn inhibition rescues established memory and synapse loss in Alzheimer mice}},
  journal = {Annals of neurology},
  year    = {2015},
  doi     = {10.1002/ana.24394},
  pmid    = {25707991},
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@article{kaushal2015-25744023,
  author  = {Kaushal, V. and Dye, R. and Pakavathkumar, P. and Foveau, B. and Flores, J. and Hyman, B. and Ghetti, B. and Koller, B. H. and others},
  title   = {{Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation}},
  journal = {Cell death and differentiation},
  year    = {2015},
  doi     = {10.1038/cdd.2015.16},
  pmid    = {25744023},
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@article{hu2015-25871773,
  author  = {Hu, J. and Liu, C. C. and Chen, X. F. and Zhang, Y. W. and Xu, H. and Bu, G.},
  title   = {{Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice}},
  journal = {Molecular neurodegeneration},
  year    = {2015},
  doi     = {10.1186/s13024-015-0001-3},
  pmid    = {25871773},
  url     = {https://doi.org/10.1186/s13024-015-0001-3}
}

@article{zhou2015-25611954,
  author  = {Zhou, Q. and Wang, M. and Du, Y. and Zhang, W. and Bai, M. and Zhang, Z. and Li, Z. and Miao, J.},
  title   = {{Inhibition of c-Jun N-terminal kinase activation reverses Alzheimer disease phenotypes in APPswe/PS1dE9 mice}},
  journal = {Annals of neurology},
  year    = {2015},
  doi     = {10.1002/ana.24361},
  pmid    = {25611954},
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}

@article{xu2015-25479064,
  author  = {Xu, W. and Yang, Y. and Yuan, G. and Zhu, W. and Ma, D. and Hu, S.},
  title   = {{Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces Alzheimer disease-associated tau hyperphosphorylation in the hippocampus of rats with type 2 diabetes}},
  journal = {Journal of investigative medicine : the official publication of the American Federation for Clinical Research},
  year    = {2015},
  doi     = {10.1097/jim.0000000000000129},
  pmid    = {25479064},
  url     = {https://doi.org/10.1097/jim.0000000000000129}
}

@article{dubal2015-25673831,
  author  = {Dubal, D. B. and Zhu, L. and Sanchez, P. E. and Worden, K. and Broestl, L. and Johnson, E. and Ho, K. and Yu, G. Q. and others},
  title   = {{Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2015},
  doi     = {10.1523/jneurosci.5791-12.2015},
  pmid    = {25673831},
  url     = {https://doi.org/10.1523/jneurosci.5791-12.2015}
}

@article{condello2015-25630253,
  author  = {Condello, Carlo and Yuan, Peng and Schain, Aaron J. and Grutzendler, Jaime},
  title   = {{Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques}},
  journal = {Nature Communications},
  year    = {2015},
  doi     = {10.1038/ncomms7176},
  pmid    = {25630253},
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}

@article{coutadeur2015-25556849,
  author  = {Coutadeur, S. and Benyamine, H. and Delalonde, L. and de Oliveira, C. and Leblond, B. and Foucourt, A. and Besson, T. and Casagrande, A. S. and others},
  title   = {{A novel DYRK1A (dual specificity tyrosine phosphorylation-regulated kinase 1A) inhibitor for the treatment of Alzheimer's disease: effect on Tau and amyloid pathologies in vitro}},
  journal = {Journal of neurochemistry},
  year    = {2015},
  doi     = {10.1111/jnc.13018},
  pmid    = {25556849},
  url     = {https://doi.org/10.1111/jnc.13018}
}

@article{peretti2015-25607368,
  author  = {Peretti, D. and Bastide, A. and Radford, H. and Verity, N. and Molloy, C. and Martin, M. G. and Moreno, J. A. and Steinert, JR. and others},
  title   = {{RBM3 mediates structural plasticity and protective effects of cooling in neurodegeneration}},
  journal = {Nature},
  year    = {2015},
  doi     = {10.1038/nature14142},
  pmid    = {25607368},
  url     = {https://doi.org/10.1038/nature14142}
}

@article{cohen2015-25556531,
  author  = {Cohen, T. J. and Hwang, A. W. and Restrepo, C. R. and Yuan, C. X. and Trojanowski, J. Q. and Lee, V. M.},
  title   = {{An acetylation switch controls TDP-43 function and aggregation propensity}},
  journal = {Nature communications},
  year    = {2015},
  doi     = {10.1038/ncomms6845},
  pmid    = {25556531},
  url     = {https://doi.org/10.1038/ncomms6845}
}

@article{wang2015-25079798,
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  title   = {{Helicobacter pylori filtrate induces Alzheimer-like tau hyperphosphorylation by activating glycogen synthase kinase-3β}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2015},
  doi     = {10.3233/jad-140198},
  pmid    = {25079798},
  url     = {https://doi.org/10.3233/jad-140198}
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@article{wilkins2015-25537010,
  author  = {Wilkins, H. M. and Carl, S. M. and Weber, S. G. and Ramanujan, S. A. and Festoff, B. W. and Linseman, D. A. and Swerdlow, R. H.},
  title   = {{Mitochondrial lysates induce inflammation and Alzheimer's disease-relevant changes in microglial and neuronal cells}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2015},
  doi     = {10.3233/jad-142334},
  pmid    = {25537010},
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}

@article{lysenko2014-25474204,
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  title   = {{Monoacylglycerol lipase inhibitor JZL184 improves behavior and neural properties in Ts65Dn mice, a model of down syndrome}},
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  pmid    = {25474204},
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@article{yang2015-25483398,
  author  = {Yang, S. and Cacquevel, M. and Saksida, L. M. and Bussey, T. J. and Schneider, B. L. and Aebischer, P. and Melani, R. and others},
  title   = {{Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology}},
  journal = {Experimental neurology},
  year    = {2015},
  doi     = {10.1016/j.expneurol.2014.11.013},
  pmid    = {25483398},
  url     = {https://doi.org/10.1016/j.expneurol.2014.11.013}
}

@article{wen2014-25521377,
  author  = {Wen, X. and Tan, W. and Westergard, T. and Krishnamurthy, K. and Markandaiah, S. S. and Shi, Y. and Lin, S. and Shneider, N. A. and others},
  title   = {{Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death}},
  journal = {Neuron},
  year    = {2014},
  doi     = {10.1016/j.neuron.2014.12.010},
  pmid    = {25521377},
  url     = {https://doi.org/10.1016/j.neuron.2014.12.010}
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@article{parr2015-25384422,
  author  = {Parr, C. and Mirzaei, N. and Christian, M. and Sastre, M.},
  title   = {{Activation of the Wnt/β-catenin pathway represses the transcription of the β-amyloid precursor protein cleaving enzyme (BACE1) via binding of T-cell factor-4 to BACE1 promoter}},
  journal = {FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year    = {2015},
  doi     = {10.1096/fj.14-253211},
  pmid    = {25384422},
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@article{yuzwa2014-25344697,
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  title   = {{Pharmacological inhibition of O-GlcNAcase (OGA) prevents cognitive decline and amyloid plaque formation in bigenic tau/APP mutant mice}},
  journal = {Molecular neurodegeneration},
  year    = {2014},
  doi     = {10.1186/1750-1326-9-42},
  pmid    = {25344697},
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}

@article{lv2015-25261783,
  author  = {Lv, C. and Wang, L. and Liu, X. and Yan, S. and Yan, S. S. and Wang, Y. and Zhang, W.},
  title   = {{Multi-faced neuroprotective effects of geniposide depending on the RAGE-mediated signaling in an Alzheimer mouse model}},
  journal = {Neuropharmacology},
  year    = {2015},
  doi     = {10.1016/j.neuropharm.2014.09.019},
  pmid    = {25261783},
  url     = {https://doi.org/10.1016/j.neuropharm.2014.09.019}
}

@article{gorrie2014-25246588,
  author  = {Gorrie, G. H. and Fecto, F. and Radzicki, D. and Weiss, C. and Shi, Y. and Dong, H. and Zhai, H. and Fu, R. and others},
  title   = {{Dendritic spinopathy in transgenic mice expressing ALS/dementia-linked mutant UBQLN2}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2014},
  doi     = {10.1073/pnas.1405741111},
  pmid    = {25246588},
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}

@article{liu2014-25242217,
  author  = {Liu, C. C. and Tsai, C. W. and Deak, F. and Rogers, J. and Penuliar, M. and Sung, Y. M. and Maher, J. N. and Fu, Y. and others},
  title   = {{Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease}},
  journal = {Neuron},
  year    = {2014},
  doi     = {10.1016/j.neuron.2014.08.048},
  pmid    = {25242217},
  url     = {https://doi.org/10.1016/j.neuron.2014.08.048}
}

@article{pisanu2014-25134730,
  author  = {Pisanu, A. and Lecca, D. and Mulas, G. and Wardas, J. and Simbula, G. and Spiga, S. and Carta, A. R.},
  title   = {{Dynamic changes in pro- and anti-inflammatory cytokines in microglia after PPAR-γ agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease}},
  journal = {Neurobiology of disease},
  year    = {2014},
  doi     = {10.1016/j.nbd.2014.08.011},
  pmid    = {25134730},
  url     = {https://doi.org/10.1016/j.nbd.2014.08.011}
}

@article{volpicellidaley2014-25122523,
  author  = {Volpicelli-Daley, L. A. and Luk, K. C. and Lee, V. M.},
  title   = {{Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite-like aggregates}},
  journal = {Nature protocols},
  year    = {2014},
  doi     = {10.1038/nprot.2014.143},
  pmid    = {25122523},
  url     = {https://doi.org/10.1038/nprot.2014.143}
}

@article{liu2014-25119742,
  author  = {Liu, C. G. and Song, J. and Zhang, Y. Q. and Wang, P. C.},
  title   = {{MicroRNA-193b is a regulator of amyloid precursor protein in the blood and cerebrospinal fluid derived exosomal microRNA-193b is a biomarker of Alzheimer's disease}},
  journal = {Molecular medicine reports},
  year    = {2014},
  doi     = {10.3892/mmr.2014.2484},
  pmid    = {25119742},
  url     = {https://doi.org/10.3892/mmr.2014.2484}
}

@article{mizielinska2014-25103406,
  author  = {Mizielinska, S. and Grönke, S. and Niccoli, T. and Ridler, C. E. and Clayton, E. L. and Devoy, A. and Moens, T. and Norona, F. E. and others},
  title   = {{C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins}},
  journal = {Science (New York, N.Y.)},
  year    = {2014},
  doi     = {10.1126/science.1256800},
  pmid    = {25103406},
  url     = {https://doi.org/10.1126/science.1256800}
}

@article{li2014-24977637,
  author  = {Li, C. and Liu, S. and Xing, Y. and Tao, F.},
  title   = {{The role of hippocampal tau protein phosphorylation in isoflurane-induced cognitive dysfunction in transgenic APP695 mice}},
  journal = {Anesthesia and analgesia},
  year    = {2014},
  doi     = {10.1213/ane.0000000000000315},
  pmid    = {24977637},
  url     = {https://doi.org/10.1213/ane.0000000000000315}
}

@article{cho2014-25126727,
  author  = {Cho, M. H. and Cho, K. and Kang, H. J. and Jeon, E. Y. and Kim, H. S. and Kwon, H. J. and Kim, H. M. and Kim, D. H. and others},
  title   = {{Autophagy in microglia degrades extracellular β-amyloid fibrils and regulates the NLRP3 inflammasome}},
  journal = {Autophagy},
  year    = {2014},
  doi     = {10.4161/auto.29647},
  pmid    = {25126727},
  url     = {https://doi.org/10.4161/auto.29647}
}

@article{brucekeller2015-25173628,
  author  = {Bruce-Keller, A. J. and Salbaum, J. M. and Luo, M. and Blanchard, E. and Taylor, C. M. and Welsh, D. A. and Berthoud, H. R.},
  title   = {{Obese-type gut microbiota induce neurobehavioral changes in the absence of obesity}},
  journal = {Biological psychiatry},
  year    = {2015},
  doi     = {10.1016/j.biopsych.2014.07.012},
  pmid    = {25173628},
  url     = {https://doi.org/10.1016/j.biopsych.2014.07.012}
}

@article{barmada2014-24974230,
  author  = {Barmada, S. J. and Serio, A. and Arjun, A. and Bilican, B. and Daub, A. and Ando, D. M. and Tsvetkov, A. and Pleiss, M. and others},
  title   = {{Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models}},
  journal = {Nature chemical biology},
  year    = {2014},
  doi     = {10.1038/nchembio.1563},
  pmid    = {24974230},
  url     = {https://doi.org/10.1038/nchembio.1563}
}

@article{bannwarth2014-24934289,
  author  = {Bannwarth, S. and Ait-El-Mkadem, S. and Chaussenot, A. and Genin, E. C. and Lacas-Gervais, S. and Fragaki, K. and Berg-Alonso, L. and Kageyama, Y. and others},
  title   = {{A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement}},
  journal = {Brain : a journal of neurology},
  year    = {2014},
  doi     = {10.1093/brain/awu138},
  pmid    = {24934289},
  url     = {https://doi.org/10.1093/brain/awu138}
}

@article{liang2014-24906968,
  author  = {Liang, P. and Wang, Z. and Qian, T. and Li, K.},
  title   = {{Acupuncture stimulation of Taichong (Liv3) and Hegu (LI4) modulates the default mode network activity in Alzheimer's disease}},
  journal = {American journal of Alzheimer's disease and other dementias},
  year    = {2014},
  doi     = {10.1177/1533317514536600},
  pmid    = {24906968},
  url     = {https://doi.org/10.1177/1533317514536600}
}

@article{stoica2014-24893131,
  author  = {Stoica, R. and De Vos, K. J. and Paillusson, S. and Mueller, S. and Sancho, R. M. and Lau, K. F. and Vizcay-Barrena, G. and Lin, W. L. and others},
  title   = {{ER-mitochondria associations are regulated by the VAPB-PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43}},
  journal = {Nature communications},
  year    = {2014},
  doi     = {10.1038/ncomms4996},
  pmid    = {24893131},
  url     = {https://doi.org/10.1038/ncomms4996}
}

@article{barberocamps2014-24815354,
  author  = {Barbero-Camps, E. and Fernández, A. and Baulies, A. and Martinez, L. and Fernández-Checa, J. C. and Colell, A.},
  title   = {{Endoplasmic reticulum stress mediates amyloid β neurotoxicity via mitochondrial cholesterol trafficking}},
  journal = {The American journal of pathology},
  year    = {2014},
  doi     = {10.1016/j.ajpath.2014.03.014},
  pmid    = {24815354},
  url     = {https://doi.org/10.1016/j.ajpath.2014.03.014}
}

@article{vasconcelos2014-24886300,
  author  = {Vasconcelos, A. R. and Yshii, L. M. and Viel, T. A. and Buck, H. S. and Mattson, M. P. and Scavone, C. and Kawamoto, E. M.},
  title   = {{Intermittent fasting attenuates lipopolysaccharide-induced neuroinflammation and memory impairment}},
  journal = {Journal of neuroinflammation},
  year    = {2014},
  doi     = {10.1186/1742-2094-11-85},
  pmid    = {24886300},
  url     = {https://doi.org/10.1186/1742-2094-11-85}
}

@article{blurtonjones2014-25022790,
  author  = {Blurton-Jones, M. and Spencer, B. and Michael, S. and Castello, N. A. and Agazaryan, A. A. and Davis, J. L. and Müller, F. J. and Loring, J. F. and others},
  title   = {{Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models}},
  journal = {Stem cell research \& therapy},
  year    = {2014},
  doi     = {10.1186/scrt440},
  pmid    = {25022790},
  url     = {https://doi.org/10.1186/scrt440}
}

@article{liu2014-24667364,
  author  = {Liu, Y. and Fu, X. and Lan, N. and Li, S. and Zhang, J. and Wang, S. and Li, C. and Shang, Y. and others},
  title   = {{Luteolin protects against high fat diet-induced cognitive deficits in obesity mice}},
  journal = {Behavioural brain research},
  year    = {2014},
  doi     = {10.1016/j.bbr.2014.02.040},
  pmid    = {24667364},
  url     = {https://doi.org/10.1016/j.bbr.2014.02.040}
}

@article{vargas2014-24658113,
  author  = {Vargas, L. M. and Leal, N. and Estrada, L. D. and González, A. and Serrano, F. and Araya, K. and Gysling, K. and Inestrosa, N. C. and others},
  title   = {{EphA4 activation of c-Abl mediates synaptic loss and LTP blockade caused by amyloid-β oligomers}},
  journal = {PloS one},
  year    = {2014},
  doi     = {10.1371/journal.pone.0092309},
  pmid    = {24658113},
  url     = {https://doi.org/10.1371/journal.pone.0092309}
}

@article{williams2014-24651765,
  author  = {Williams, SR. and Yang, Q. and Chen, F. and Liu, X. and Keene, K. L. and Jacques, P. and Chen, W. M. and Weinstein, G. and others},
  title   = {{Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke}},
  journal = {PLoS genetics},
  year    = {2014},
  doi     = {10.1371/journal.pgen.1004214},
  pmid    = {24651765},
  url     = {https://doi.org/10.1371/journal.pgen.1004214}
}

@article{haeusler2014-24598541,
  author  = {Haeusler, A. R. and Donnelly, C. J. and Periz, G. and Simko, E. A. and Shaw, P. G. and Kim, M. S. and Maragakis, N. J. and Troncoso, J. C. and others},
  title   = {{C9orf72 nucleotide repeat structures initiate molecular cascades of disease}},
  journal = {Nature},
  year    = {2014},
  doi     = {10.1038/nature13124},
  pmid    = {24598541},
  url     = {https://doi.org/10.1038/nature13124}
}

@article{selenica2014-24576665,
  author  = {Selenica, M. L. and Benner, L. and Housley, S. B. and Manchec, B. and Lee, D. C. and Nash, K. R. and Kalin, J. and Bergman, J. A. and others},
  title   = {{Histone deacetylase 6 inhibition improves memory and reduces total tau levels in a mouse model of tau deposition}},
  journal = {Alzheimer's research \& therapy},
  year    = {2014},
  doi     = {10.1186/alzrt241},
  pmid    = {24576665},
  url     = {https://doi.org/10.1186/alzrt241}
}

@article{farg2014-24549040,
  author  = {Farg, M. A. and Sundaramoorthy, V. and Sultana, J. M. and Yang, S. and Atkinson, R. A. and Levina, V. and Halloran, M. A. and Gleeson, P. A. and others},
  title   = {{C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking}},
  journal = {Human molecular genetics},
  year    = {2014},
  doi     = {10.1093/hmg/ddu068},
  pmid    = {24549040},
  url     = {https://doi.org/10.1093/hmg/ddu068}
}

@article{gao2014-24329968,
  author  = {Gao, C. and Liu, Y. and Jiang, Y. and Ding, J. and Li, L.},
  title   = {{Geniposide ameliorates learning memory deficits, reduces tau phosphorylation and decreases apoptosis via GSK3β pathway in streptozotocin-induced alzheimer rat model}},
  journal = {Brain pathology (Zurich, Switzerland)},
  year    = {2014},
  doi     = {10.1111/bpa.12116},
  pmid    = {24329968},
  url     = {https://doi.org/10.1111/bpa.12116}
}

@article{alami2014-24507191,
  author  = {Alami, N. H. and Smith, R. B. and Carrasco, M. A. and Williams, L. A. and Winborn, C. S. and Han, S. S. W. and Kiskinis, E. and Winborn, B. and others},
  title   = {{Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations}},
  journal = {Neuron},
  year    = {2014},
  doi     = {10.1016/j.neuron.2013.12.018},
  pmid    = {24507191},
  url     = {https://doi.org/10.1016/j.neuron.2013.12.018}
}

@article{sclip2014-24457963,
  author  = {Sclip, A. and Tozzi, A. and Abaza, A. and Cardinetti, D. and Colombo, I. and Calabresi, P. and Salmona, M. and Welker, E. and others},
  title   = {{c-Jun N-terminal kinase has a key role in Alzheimer disease synaptic dysfunction in vivo}},
  journal = {Cell death \& disease},
  year    = {2014},
  doi     = {10.1038/cddis.2013.559},
  pmid    = {24457963},
  url     = {https://doi.org/10.1038/cddis.2013.559}
}

@article{scotter2014-24424030,
  author  = {Scotter, E. L. and Vance, C. and Nishimura, A. L. and Lee, Y. B. and Chen, H. J. and Urwin, H. and Sardone, V. and Mitchell, J. C. and others},
  title   = {{Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species}},
  journal = {Journal of cell science},
  year    = {2014},
  doi     = {10.1242/jcs.140087},
  pmid    = {24424030},
  url     = {https://doi.org/10.1242/jcs.140087}
}

@article{trudler2014-24355073,
  author  = {Trudler, D. and Weinreb, O. and Mandel, S. A. and Youdim, M. B. and Frenkel, D.},
  title   = {{DJ-1 deficiency triggers microglia sensitivity to dopamine toward a pro-inflammatory phenotype that is attenuated by rasagiline}},
  journal = {Journal of neurochemistry},
  year    = {2014},
  doi     = {10.1111/jnc.12633},
  pmid    = {24355073},
  url     = {https://doi.org/10.1111/jnc.12633}
}

@article{matsumura2014-24375443,
  author  = {Matsumura, N. and Takami, M. and Okochi, M. and Wada-Kakuda, S. and Fujiwara, H. and Tagami, S. and Funamoto, S. and Ihara, Y. and others},
  title   = {{γ-Secretase associated with lipid rafts: multiple interactive pathways in the stepwise processing of β-carboxyl-terminal fragment}},
  journal = {The Journal of biological chemistry},
  year    = {2014},
  doi     = {10.1074/jbc.m113.510131},
  pmid    = {24375443},
  url     = {https://doi.org/10.1074/jbc.m113.510131}
}

@article{asuni2014-24366862,
  author  = {Asuni, A. A. and Gray, B. and Bailey, J. and Skipp, P. and Perry, V. H. and O'Connor, V.},
  title   = {{Analysis of the hippocampal proteome in ME7 prion disease reveals a predominant astrocytic signature and highlights the brain-restricted production of clusterin in chronic neurodegeneration}},
  journal = {The Journal of biological chemistry},
  year    = {2014},
  doi     = {10.1074/jbc.m113.502690},
  pmid    = {24366862},
  url     = {https://doi.org/10.1074/jbc.m113.502690}
}

@article{currais2014-24341874,
  author  = {Currais, A. and Prior, M. and Dargusch, R. and Armando, A. and Ehren, J. and Schubert, D. and Quehenberger, O. and Maher, P.},
  title   = {{Modulation of p25 and inflammatory pathways by fisetin maintains cognitive function in Alzheimer's disease transgenic mice}},
  journal = {Aging cell},
  year    = {2014},
  doi     = {10.1111/acel.12185},
  pmid    = {24341874},
  url     = {https://doi.org/10.1111/acel.12185}
}

@article{jiang2014-24368090,
  author  = {Jiang, T. and Yu, J. T. and Zhu, X. C. and Tan, M. S. and Gu, L. Z. and Zhang, Y. D. and Tan, L.},
  title   = {{Triggering receptor expressed on myeloid cells 2 knockdown exacerbates aging-related neuroinflammation and cognitive deficiency in senescence-accelerated mouse prone 8 mice}},
  journal = {Neurobiology of aging},
  year    = {2014},
  doi     = {10.1016/j.neurobiolaging.2013.11.026},
  pmid    = {24368090},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2013.11.026}
}

@article{miller2013-24315443,
  author  = {Miller, J. D. and Ganat, Y. M. and Kishinevsky, S. and Bowman, R. L. and Liu, B. and Tu, E. Y. and Mandal, P. K. and Vera, E. and others},
  title   = {{Human iPSC-based modeling of late-onset disease via progerin-induced aging}},
  journal = {Cell stem cell},
  year    = {2013},
  doi     = {10.1016/j.stem.2013.11.006},
  pmid    = {24315443},
  url     = {https://doi.org/10.1016/j.stem.2013.11.006}
}

@article{kanekiyo2013-24305823,
  author  = {Kanekiyo, T. and Cirrito, JR. and Liu, C. C. and Shinohara, M. and Li, J. and Schuler, D. R. and Holtzman, D. M. and others},
  title   = {{Neuronal clearance of amyloid-β by endocytic receptor LRP1}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2013},
  doi     = {10.1523/jneurosci.3487-13.2013},
  pmid    = {24305823},
  url     = {https://doi.org/10.1523/jneurosci.3487-13.2013}
}

@article{herskowitz2013-24305806,
  author  = {Herskowitz, J. H. and Feng, Y. and Mattheyses, A. L. and Hales, C. M. and Higginbotham, L. A. and Duong, D. M. and Montine, T. J. and Troncoso, J. C. and others},
  title   = {{Pharmacologic inhibition of ROCK2 suppresses amyloid-β production in an Alzheimer's disease mouse model}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2013},
  doi     = {10.1523/jneurosci.2508-13.2013},
  pmid    = {24305806},
  url     = {https://doi.org/10.1523/jneurosci.2508-13.2013}
}

@article{mendelsohn2013-24199995,
  author  = {Mendelsohn, A. R. and Larrick, J. W.},
  title   = {{Sleep facilitates clearance of metabolites from the brain: glymphatic function in aging and neurodegenerative diseases}},
  journal = {Rejuvenation research},
  year    = {2013},
  doi     = {10.1089/rej.2013.1530},
  pmid    = {24199995},
  url     = {https://doi.org/10.1089/rej.2013.1530}
}

@article{lee2013-24290757,
  author  = {Lee, Y. B. and Chen, H. J. and Peres, J. N. and Gomez-Deza, J. and Attig, J. and Stalekar, M. and Troakes, C. and Nishimura, A. L. and others},
  title   = {{Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic}},
  journal = {Cell reports},
  year    = {2013},
  doi     = {10.1016/j.celrep.2013.10.049},
  pmid    = {24290757},
  url     = {https://doi.org/10.1016/j.celrep.2013.10.049}
}

@article{tomioka2014-24265310,
  author  = {Tomioka, T. and Shimazaki, T. and Yamauchi, T. and Oki, T. and Ohgoh, M. and Okano, H.},
  title   = {{LIM homeobox 8 (Lhx8) is a key regulator of the cholinergic neuronal function via a tropomyosin receptor kinase A (TrkA)-mediated positive feedback loop}},
  journal = {The Journal of biological chemistry},
  year    = {2014},
  doi     = {10.1074/jbc.m113.494385},
  pmid    = {24265310},
  url     = {https://doi.org/10.1074/jbc.m113.494385}
}

@article{zu2013-24248382,
  author  = {Zu, T. and Liu, Y. and Bañez-Coronel, M. and Reid, T. and Pletnikova, O. and Lewis, J. and Miller, T. M. and Harms, M. B. and others},
  title   = {{RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2013},
  doi     = {10.1073/pnas.1315438110},
  pmid    = {24248382},
  url     = {https://doi.org/10.1073/pnas.1315438110}
}

@article{watts2013-24218576,
  author  = {Watts, J. C. and Giles, K. and Oehler, A. and Middleton, L. and Dexter, D. T. and Gentleman, S. M. and DeArmond, S. J. and Prusiner, S. B.},
  title   = {{Transmission of multiple system atrophy prions to transgenic mice}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2013},
  doi     = {10.1073/pnas.1318268110},
  pmid    = {24218576},
  url     = {https://doi.org/10.1073/pnas.1318268110}
}

@article{lagiertourenne2013-24170860,
  author  = {Lagier-Tourenne, C. and Baughn, M. and Rigo, F. and Sun, S. and Liu, P. and Li, H. R. and Jiang, J. and Watt, A. T. and others},
  title   = {{Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2013},
  doi     = {10.1073/pnas.1318835110},
  pmid    = {24170860},
  url     = {https://doi.org/10.1073/pnas.1318835110}
}

@article{mori2013-24132570,
  author  = {Mori, K. and Arzberger, T. and Grässer, F. A. and Gijselinck, I. and May, S. and Rentzsch, K. and Weng, S. M. and Schludi, M. H. and others},
  title   = {{Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins}},
  journal = {Acta neuropathologica},
  year    = {2013},
  doi     = {10.1007/s00401-013-1189-3},
  pmid    = {24132570},
  url     = {https://doi.org/10.1007/s00401-013-1189-3}
}

@article{gendron2013-24129584,
  author  = {Gendron, T. F. and Bieniek, K. F. and Zhang, Y. J. and Jansen-West, K. and Ash, P. E. and Caulfield, T. and Daughrity, L. and Dunmore, J. H. and others},
  title   = {{Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS}},
  journal = {Acta neuropathologica},
  year    = {2013},
  doi     = {10.1007/s00401-013-1192-8},
  pmid    = {24129584},
  url     = {https://doi.org/10.1007/s00401-013-1192-8}
}

@article{neher2013-24101459,
  author  = {Neher, J. J. and Emmrich, J. V. and Fricker, M. and Mander, P. K. and Théry, C. and Brown, G. C.},
  title   = {{Phagocytosis executes delayed neuronal death after focal brain ischemia}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2013},
  doi     = {10.1073/pnas.1308679110},
  pmid    = {24101459},
  url     = {https://doi.org/10.1073/pnas.1308679110}
}

@article{mackenzie2013-24096617,
  author  = {Mackenzie, I. R. and Arzberger, T. and Kremmer, E. and Troost, D. and Lorenzl, S. and Mori, K. and Weng, S. M. and Haass, C. and others},
  title   = {{Dipeptide repeat protein pathology in C9ORF72 mutation cases: clinico-pathological correlations}},
  journal = {Acta neuropathologica},
  year    = {2013},
  doi     = {10.1007/s00401-013-1181-y},
  pmid    = {24096617},
  url     = {https://doi.org/10.1007/s00401-013-1181-y}
}

@article{donnelly2013-24139042,
  author  = {Donnelly, C. J. and Zhang, P. W. and Pham, J. T. and Haeusler, A. R. and Mistry, N. A. and Vidensky, S. and Daley, E. L. and Poth, E. M. and others},
  title   = {{RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention}},
  journal = {Neuron},
  year    = {2013},
  doi     = {10.1016/j.neuron.2013.10.015},
  pmid    = {24139042},
  url     = {https://doi.org/10.1016/j.neuron.2013.10.015}
}

@article{sareen2013-24154603,
  author  = {Sareen, D. and O'Rourke, J. G. and Meera, P. and Muhammad, A. K. and Grant, S. and Simpkinson, M. and Bell, S. and Carmona, S. and others},
  title   = {{Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion}},
  journal = {Science translational medicine},
  year    = {2013},
  doi     = {10.1126/scitranslmed.3007529},
  pmid    = {24154603},
  url     = {https://doi.org/10.1126/scitranslmed.3007529}
}

@article{wang2013-24036913,
  author  = {Wang, W. Y. and Pan, L. and Su, S. C. and Quinn, E. J. and Sasaki, M. and Jimenez, J. C. and Mackenzie, I. R. and Huang, E. J. and others},
  title   = {{Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons}},
  journal = {Nature neuroscience},
  year    = {2013},
  doi     = {10.1038/nn.3514},
  pmid    = {24036913},
  url     = {https://doi.org/10.1038/nn.3514}
}

@article{ross2013-23968157,
  author  = {Ross, J. and Sharma, S. and Winston, J. and Nunez, M. and Bottini, G. and Franceschi, M. and Scarpini, E. and Frigerio, E. and others},
  title   = {{CHF5074 reduces biomarkers of neuroinflammation in patients with mild cognitive impairment: a 12-week, double-blind, placebo-controlled study}},
  journal = {Current Alzheimer research},
  year    = {2013},
  doi     = {10.2174/13892037113149990144},
  pmid    = {23968157},
  url     = {https://doi.org/10.2174/13892037113149990144}
}

@article{ew2013-24048854,
  author  = {ÉW, Griffin and Skelly, D. T. and Murray, C. L. and Cunningham, C.},
  title   = {{Cyclooxygenase-1-dependent prostaglandins mediate susceptibility to systemic inflammation-induced acute cognitive dysfunction}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2013},
  doi     = {10.1523/jneurosci.6361-11.2013},
  pmid    = {24048854},
  url     = {https://doi.org/10.1523/jneurosci.6361-11.2013}
}

@article{lucin2013-24012002,
  author  = {Lucin, K. M. and O'Brien, C. E. and Bieri, G. and Czirr, E. and Mosher, K. I. and Abbey, R. J. and Mastroeni, D. F. and Rogers, J. and others},
  title   = {{Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease}},
  journal = {Neuron},
  year    = {2013},
  doi     = {10.1016/j.neuron.2013.06.046},
  pmid    = {24012002},
  url     = {https://doi.org/10.1016/j.neuron.2013.06.046}
}

@article{chen2014-23996345,
  author  = {Chen, Y. and Liang, Z. and Tian, Z. and Blanchard, J. and Dai, C. L. and Chalbot, S. and Iqbal, K. and Liu, F. and others},
  title   = {{Intracerebroventricular streptozotocin exacerbates Alzheimer-like changes of 3xTg-AD mice}},
  journal = {Molecular neurobiology},
  year    = {2014},
  doi     = {10.1007/s12035-013-8539-y},
  pmid    = {23996345},
  url     = {https://doi.org/10.1007/s12035-013-8539-y}
}

@article{peng2013-23962980,
  author  = {Peng, Q. and Long, C. L. and Malhotra, S. and Humphrey, M. B.},
  title   = {{A physical interaction between the adaptor proteins DOK3 and DAP12 is required to inhibit lipopolysaccharide signaling in macrophages}},
  journal = {Science signaling},
  year    = {2013},
  doi     = {10.1126/scisignal.2003801},
  pmid    = {23962980},
  url     = {https://doi.org/10.1126/scisignal.2003801}
}

@article{grossi2013-23951225,
  author  = {Grossi, C. and Rigacci, S. and Ambrosini, S. and Ed Dami, T. and Luccarini, I. and Traini, C. and Failli, P. and Berti, A. and others},
  title   = {{The polyphenol oleuropein aglycone protects TgCRND8 mice against Aß plaque pathology}},
  journal = {PloS one},
  year    = {2013},
  doi     = {10.1371/journal.pone.0071702},
  pmid    = {23951225},
  url     = {https://doi.org/10.1371/journal.pone.0071702}
}

@article{ling2013-23931993,
  author  = {Ling, S. C. and Polymenidou, M. and Cleveland, D. W.},
  title   = {{Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis}},
  journal = {Neuron},
  year    = {2013},
  doi     = {10.1016/j.neuron.2013.07.033},
  pmid    = {23931993},
  url     = {https://doi.org/10.1016/j.neuron.2013.07.033}
}

@article{friedman2013-23689947,
  author  = {Friedman, S. D. and Baker, L. D. and Borson, S. and Jensen, J. E. and Barsness, S. M. and Craft, S. and Merriam, G. R. and Otto, R. K. and others},
  title   = {{Growth hormone-releasing hormone effects on brain γ-aminobutyric acid levels in mild cognitive impairment and healthy aging}},
  journal = {JAMA neurology},
  year    = {2013},
  doi     = {10.1001/jamaneurol.2013.1425},
  pmid    = {23689947},
  url     = {https://doi.org/10.1001/jamaneurol.2013.1425}
}

@article{willnow2013-23813966,
  author  = {Willnow, T. E. and Andersen, O. M.},
  title   = {{Sorting receptor SORLA--a trafficking path to avoid Alzheimer disease}},
  journal = {Journal of cell science},
  year    = {2013},
  doi     = {10.1242/jcs.125393},
  pmid    = {23813966},
  url     = {https://doi.org/10.1242/jcs.125393}
}

@article{silvaalvarez2013-23805073,
  author  = {Silva-Alvarez, C. and Arrázola, M. S. and Godoy, J. A. and Ordenes, D. and Inestrosa, N. C.},
  title   = {{Canonical Wnt signaling protects hippocampal neurons from Aβ oligomers: role of non-canonical Wnt-5a/Ca(2+) in mitochondrial dynamics}},
  journal = {Frontiers in cellular neuroscience},
  year    = {2013},
  doi     = {10.3389/fncel.2013.00097},
  pmid    = {23805073},
  url     = {https://doi.org/10.3389/fncel.2013.00097}
}

@article{buchan2013-23791177,
  author  = {Buchan, JR. and Kolaitis, R. M. and Taylor, J. P. and Parker, R.},
  title   = {{Eukaryotic stress granules are cleared by autophagy and Cdc48/VCP function}},
  journal = {Cell},
  year    = {2013},
  doi     = {10.1016/j.cell.2013.05.037},
  pmid    = {23791177},
  url     = {https://doi.org/10.1016/j.cell.2013.05.037}
}

@article{balu2013-23729812,
  author  = {Balu, D. T. and Li, Y. and Puhl, M. D. and Benneyworth, M. A. and Basu, A. C. and Takagi, S. and Bolshakov, V. Y. and Coyle, J. T.},
  title   = {{Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2013},
  doi     = {10.1073/pnas.1304308110},
  pmid    = {23729812},
  url     = {https://doi.org/10.1073/pnas.1304308110}
}

@article{ando2013-23589030,
  author  = {Ando, K. and Brion, J. P. and Stygelbout, V. and Suain, V. and Authelet, M. and Dedecker, R. and Chanut, A. and Lacor, P. and others},
  title   = {{Clathrin adaptor CALM/PICALM is associated with neurofibrillary tangles and is cleaved in Alzheimer's brains}},
  journal = {Acta neuropathologica},
  year    = {2013},
  doi     = {10.1007/s00401-013-1111-z},
  pmid    = {23589030},
  url     = {https://doi.org/10.1007/s00401-013-1111-z}
}

@article{giraldo2013-23582655,
  author  = {Giraldo, M. and Lopera, F. and Siniard, A. L. and Corneveaux, J. J. and Schrauwen, I. and Carvajal, J. and Muñoz, C. and Ramirez-Restrepo, M. and others},
  title   = {{Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease}},
  journal = {Neurobiology of aging},
  year    = {2013},
  doi     = {10.1016/j.neurobiolaging.2013.02.016},
  pmid    = {23582655},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2013.02.016}
}

@article{sahm2013-23548271,
  author  = {Sahm, F. and Oezen, I. and Opitz, C. A. and Radlwimmer, B. and von Deimling, A. and Ahrendt, T. and Adams, S. and Bode, H. B. and others},
  title   = {{The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress}},
  journal = {Cancer research},
  year    = {2013},
  doi     = {10.1158/0008-5472.can-12-3831},
  pmid    = {23548271},
  url     = {https://doi.org/10.1158/0008-5472.can-12-3831}
}

@article{kuszczyk2013-23499462,
  author  = {Kuszczyk, M. A. and Sanchez, S. and Pankiewicz, J. and Kim, J. and Duszczyk, M. and Guridi, M. and Asuni, A. A. and Sullivan, P. M. and others},
  title   = {{Blocking the interaction between apolipoprotein E and Aβ reduces intraneuronal accumulation of Aβ and inhibits synaptic degeneration}},
  journal = {The American journal of pathology},
  year    = {2013},
  doi     = {10.1016/j.ajpath.2013.01.034},
  pmid    = {23499462},
  url     = {https://doi.org/10.1016/j.ajpath.2013.01.034}
}

@article{rojanathammanee2013-23468550,
  author  = {Rojanathammanee, L. and Puig, K. L. and Combs, C. K.},
  title   = {{Pomegranate polyphenols and extract inhibit nuclear factor of activated T-cell activity and microglial activation in vitro and in a transgenic mouse model of Alzheimer disease}},
  journal = {The Journal of nutrition},
  year    = {2013},
  doi     = {10.3945/jn.112.169516},
  pmid    = {23468550},
  url     = {https://doi.org/10.3945/jn.112.169516}
}

@article{oneill2013-23470275,
  author  = {O' Neill, C.},
  title   = {{PI3-kinase/Akt/mTOR signaling: impaired on/off switches in aging, cognitive decline and Alzheimer's disease}},
  journal = {Experimental gerontology},
  year    = {2013},
  doi     = {10.1016/j.exger.2013.02.025},
  pmid    = {23470275},
  url     = {https://doi.org/10.1016/j.exger.2013.02.025}
}

@article{shimizu2013-23428182,
  author  = {Shimizu, F. and Sano, Y. and Tominaga, O. and Maeda, T. and Abe, M. A. and Kanda, T.},
  title   = {{Advanced glycation end-products disrupt the blood-brain barrier by stimulating the release of transforming growth factor-β by pericytes and vascular endothelial growth factor and matrix metalloproteinase-2 by endothelial cells in vitro}},
  journal = {Neurobiology of aging},
  year    = {2013},
  doi     = {10.1016/j.neurobiolaging.2013.01.012},
  pmid    = {23428182},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2013.01.012}
}

@article{ash2013-23415312,
  author  = {Ash, P. E. and Bieniek, K. F. and Gendron, T. F. and Caulfield, T. and Lin, W. L. and Dejesus-Hernandez, M. and van Blitterswijk, M. M. and Jansen-West, K. and others},
  title   = {{Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS}},
  journal = {Neuron},
  year    = {2013},
  doi     = {10.1016/j.neuron.2013.02.004},
  pmid    = {23415312},
  url     = {https://doi.org/10.1016/j.neuron.2013.02.004}
}

@article{serio2013-23401527,
  author  = {Serio, A. and Bilican, B. and Barmada, S. J. and Ando, D. M. and Zhao, C. and Siller, R. and Burr, K. and Haghi, G. and others},
  title   = {{Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2013},
  doi     = {10.1073/pnas.1300398110},
  pmid    = {23401527},
  url     = {https://doi.org/10.1073/pnas.1300398110}
}

@article{mori2013-23409038,
  author  = {Mori, T. and Koyama, N. and Guillot-Sestier, M. V. and Tan, J. and Town, T.},
  title   = {{Ferulic acid is a nutraceutical β-secretase modulator that improves behavioral impairment and alzheimer-like pathology in transgenic mice}},
  journal = {PloS one},
  year    = {2013},
  doi     = {10.1371/journal.pone.0055774},
  pmid    = {23409038},
  url     = {https://doi.org/10.1371/journal.pone.0055774}
}

@article{pozdnyakov2013-23396974,
  author  = {Pozdnyakov, N. and Murrey, H. E. and Crump, C. J. and Pettersson, M. and Ballard, T. E. and Am Ende, C. W. and Ahn, K. and Li, Y. M. and others},
  title   = {{γ-Secretase modulator (GSM) photoaffinity probes reveal distinct allosteric binding sites on presenilin}},
  journal = {The Journal of biological chemistry},
  year    = {2013},
  doi     = {10.1074/jbc.m112.398602},
  pmid    = {23396974},
  url     = {https://doi.org/10.1074/jbc.m112.398602}
}

@article{mori2013-23393093,
  author  = {Mori, K. and Weng, S. M. and Arzberger, T. and May, S. and Rentzsch, K. and Kremmer, E. and Schmid, B. and Kretzschmar, H. A. and others},
  title   = {{The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS}},
  journal = {Science (New York, N.Y.)},
  year    = {2013},
  doi     = {10.1126/science.1232927},
  pmid    = {23393093},
  url     = {https://doi.org/10.1126/science.1232927}
}

@article{rushworth2013-23386614,
  author  = {Rushworth, J. V. and Griffiths, H. H. and Watt, N. T. and Hooper, N. M.},
  title   = {{Prion protein-mediated toxicity of amyloid-β oligomers requires lipid rafts and the transmembrane LRP1}},
  journal = {The Journal of biological chemistry},
  year    = {2013},
  doi     = {10.1074/jbc.m112.400358},
  pmid    = {23386614},
  url     = {https://doi.org/10.1074/jbc.m112.400358}
}

@article{arnold2013-23382207,
  author  = {Arnold, E. S. and Ling, S. C. and Huelga, S. C. and Lagier-Tourenne, C. and Polymenidou, M. and Ditsworth, D. and Kordasiewicz, H. B. and McAlonis-Downes, M. and others},
  title   = {{ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2013},
  doi     = {10.1073/pnas.1222809110},
  pmid    = {23382207},
  url     = {https://doi.org/10.1073/pnas.1222809110}
}

@article{ermak2013-23369757,
  author  = {Ermak, G. and Davies, K. J. A.},
  title   = {{Chronic high levels of the RCAN1-1 protein may promote neurodegeneration and Alzheimer disease}},
  journal = {Free radical biology \& medicine},
  year    = {2013},
  doi     = {10.1016/j.freeradbiomed.2013.01.016},
  pmid    = {23369757},
  url     = {https://doi.org/10.1016/j.freeradbiomed.2013.01.016}
}

@article{fluharty2013-23362282,
  author  = {Fluharty, B. R. and Biasini, E. and Stravalaci, M. and Sclip, A. and Diomede, L. and Balducci, C. and La Vitola, P. and Messa, M. and others},
  title   = {{An N-terminal fragment of the prion protein binds to amyloid-β oligomers and inhibits their neurotoxicity in vivo}},
  journal = {The Journal of biological chemistry},
  year    = {2013},
  doi     = {10.1074/jbc.m112.423954},
  pmid    = {23362282},
  url     = {https://doi.org/10.1074/jbc.m112.423954}
}

@article{michaud2013-23322736,
  author  = {Michaud, J. P. and Hallé, M. and Lampron, A. and Thériault, P. and Préfontaine, P. and Filali, M. and Tribout-Jover, P. and Lanteigne, A. M. and others},
  title   = {{Toll-like receptor 4 stimulation with the detoxified ligand monophosphoryl lipid A improves Alzheimer's disease-related pathology}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2013},
  doi     = {10.1073/pnas.1215165110},
  pmid    = {23322736},
  url     = {https://doi.org/10.1073/pnas.1215165110}
}

@article{smith2013-23297359,
  author  = {Smith, K. R. and Dahl, H. H. and Canafoglia, L. and Andermann, E. and Damiano, J. and Morbin, M. and Bruni, A. C. and Giaccone, G. and others},
  title   = {{Cathepsin F mutations cause Type B Kufs disease, an adult-onset neuronal ceroid lipofuscinosis}},
  journal = {Human molecular genetics},
  year    = {2013},
  doi     = {10.1093/hmg/dds558},
  pmid    = {23297359},
  url     = {https://doi.org/10.1093/hmg/dds558}
}

@article{casarejos2013-23478312,
  author  = {Casarejos, M. J. and Perucho, J. and Gomez, A. and Muñoz, M. P. and Fernandez-Estevez, M. and Sagredo, O. and Fernandez Ruiz, J. and Guzman, M. and others},
  title   = {{Natural cannabinoids improve dopamine neurotransmission and tau and amyloid pathology in a mouse model of tauopathy}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2013},
  doi     = {10.3233/jad-130050},
  pmid    = {23478312},
  url     = {https://doi.org/10.3233/jad-130050}
}

@article{guo2013-23262393,
  author  = {Guo, C. and Wang, P. and Zhong, M. L. and Wang, T. and Huang, X. S. and Li, J. Y. and Wang, Z. Y.},
  title   = {{Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain}},
  journal = {Neurochemistry international},
  year    = {2013},
  doi     = {10.1016/j.neuint.2012.12.005},
  pmid    = {23262393},
  url     = {https://doi.org/10.1016/j.neuint.2012.12.005}
}

@article{avrahami2013-23155049,
  author  = {Avrahami, L. and Farfara, D. and Shaham-Kol, M. and Vassar, R. and Frenkel, D. and Eldar-Finkelman, H.},
  title   = {{Inhibition of glycogen synthase kinase-3 ameliorates β-amyloid pathology and restores lysosomal acidification and mammalian target of rapamycin activity in the Alzheimer disease mouse model: in vivo and in vitro studies}},
  journal = {The Journal of biological chemistry},
  year    = {2013},
  doi     = {10.1074/jbc.m112.409250},
  pmid    = {23155049},
  url     = {https://doi.org/10.1074/jbc.m112.409250}
}

@article{martens2012-23041626,
  author  = {Martens, L. H. and Zhang, J. and Barmada, S. J. and Zhou, P. and Kamiya, S. and Sun, B. and Min, S. W. and Gan, L. and others},
  title   = {{Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury}},
  journal = {The Journal of clinical investigation},
  year    = {2012},
  doi     = {10.1172/jci63113},
  pmid    = {23041626},
  url     = {https://doi.org/10.1172/jci63113}
}

@article{imaizumi2012-23039195,
  author  = {Imaizumi, Y. and Okada, Y. and Akamatsu, W. and Koike, M. and Kuzumaki, N. and Hayakawa, H. and Nihira, T. and Kobayashi, T. and others},
  title   = {{Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue}},
  journal = {Molecular brain},
  year    = {2012},
  doi     = {10.1186/1756-6606-5-35},
  pmid    = {23039195},
  url     = {https://doi.org/10.1186/1756-6606-5-35}
}

@article{haining2012-23035126,
  author  = {Haining, E. J. and Yang, J. and Bailey, R. L. and Khan, K. and Collier, R. and Tsai, S. and Watson, S. P. and Frampton, J. and others},
  title   = {{The TspanC8 subgroup of tetraspanins interacts with A disintegrin and metalloprotease 10 (ADAM10) and regulates its maturation and cell surface expression}},
  journal = {The Journal of biological chemistry},
  year    = {2012},
  doi     = {10.1074/jbc.m112.416503},
  pmid    = {23035126},
  url     = {https://doi.org/10.1074/jbc.m112.416503}
}

@article{lagiertourenne2012-23023293,
  author  = {Lagier-Tourenne, C. and Polymenidou, M. and Hutt, K. R. and Vu, A. Q. and Baughn, M. and Huelga, S. C. and Clutario, K. M. and Ling, S. C. and others},
  title   = {{Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs}},
  journal = {Nature neuroscience},
  year    = {2012},
  doi     = {10.1038/nn.3230},
  pmid    = {23023293},
  url     = {https://doi.org/10.1038/nn.3230}
}

@article{perez2012-23071869,
  author  = {Perez, S. E. and Nadeem, M. and Sadleir, K. R. and Matras, J. and Kelley, C. M. and Counts, S. E. and Vassar, R. and Mufson, E. J.},
  title   = {{Dimebon alters hippocampal amyloid pathology in 3xTg-AD mice}},
  journal = {International journal of physiology, pathophysiology and pharmacology},
  year    = {2012},
  pmid    = {23071869}
}

@article{liu2012-22989295,
  author  = {Liu, R. and Wu, C. X. and Zhou, D. and Yang, F. and Tian, S. and Zhang, L. and Zhang, T. T. and Du, G. H.},
  title   = {{Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulating mitochondrion-mediated apoptosis}},
  journal = {BMC medicine},
  year    = {2012},
  doi     = {10.1186/1741-7015-10-105},
  pmid    = {22989295},
  url     = {https://doi.org/10.1186/1741-7015-10-105}
}

@article{hitt2012-22988240,
  author  = {Hitt, B. and Riordan, S. M. and Kukreja, L. and Eimer, W. A. and Rajapaksha, T. W. and Vassar, R.},
  title   = {{β-Site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1)-deficient mice exhibit a close homolog of L1 (CHL1) loss-of-function phenotype involving axon guidance defects}},
  journal = {The Journal of biological chemistry},
  year    = {2012},
  doi     = {10.1074/jbc.m112.415505},
  pmid    = {22988240},
  url     = {https://doi.org/10.1074/jbc.m112.415505}
}

@article{bae2012-23015436,
  author  = {Bae, E. J. and Lee, H. J. and Rockenstein, E. and Ho, D. H. and Park, E. B. and Yang, N. Y. and Desplats, P. and Masliah, E. and others},
  title   = {{Antibody-aided clearance of extracellular α-synuclein prevents cell-to-cell aggregate transmission}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2012},
  doi     = {10.1523/jneurosci.1292-12.2012},
  pmid    = {23015436},
  url     = {https://doi.org/10.1523/jneurosci.1292-12.2012}
}

@article{wang2012-22932872,
  author  = {Wang, I. F. and Guo, B. S. and Liu, Y. C. and Wu, C. C. and Yang, C. H. and Tsai, K. J. and Shen, C. K.},
  title   = {{Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2012},
  doi     = {10.1073/pnas.1206362109},
  pmid    = {22932872},
  url     = {https://doi.org/10.1073/pnas.1206362109}
}

@article{tokutake2012-22910909,
  author  = {Tokutake, T. and Kasuga, K. and Yajima, R. and Sekine, Y. and Tezuka, T. and Nishizawa, M. and Ikeuchi, T.},
  title   = {{Hyperphosphorylation of Tau induced by naturally secreted amyloid-β at nanomolar concentrations is modulated by insulin-dependent Akt-GSK3β signaling pathway}},
  journal = {The Journal of biological chemistry},
  year    = {2012},
  doi     = {10.1074/jbc.m112.348300},
  pmid    = {22910909},
  url     = {https://doi.org/10.1074/jbc.m112.348300}
}

@article{russell2012-22905234,
  author  = {Russell, C. L. and Semerdjieva, S. and Empson, R. M. and Austen, B. M. and Beesley, P. W. and Alifragis, P.},
  title   = {{Amyloid-β acts as a regulator of neurotransmitter release disrupting the interaction between synaptophysin and VAMP2}},
  journal = {PloS one},
  year    = {2012},
  doi     = {10.1371/journal.pone.0043201},
  pmid    = {22905234},
  url     = {https://doi.org/10.1371/journal.pone.0043201}
}

@article{kamphuis2012-22912745,
  author  = {Kamphuis, W. and Mamber, C. and Moeton, M. and Kooijman, L. and Sluijs, J. A. and Jansen, A. H. and Verveer, M. and de Groot, L. R. and others},
  title   = {{GFAP isoforms in adult mouse brain with a focus on neurogenic astrocytes and reactive astrogliosis in mouse models of Alzheimer disease}},
  journal = {PloS one},
  year    = {2012},
  doi     = {10.1371/journal.pone.0042823},
  pmid    = {22912745},
  url     = {https://doi.org/10.1371/journal.pone.0042823}
}

@article{schaeffer2012-22874558,
  author  = {Schaeffer, V. and Goedert, M.},
  title   = {{Stimulation of autophagy is neuroprotective in a mouse model of human tauopathy}},
  journal = {Autophagy},
  year    = {2012},
  doi     = {10.4161/auto.21488},
  pmid    = {22874558},
  url     = {https://doi.org/10.4161/auto.21488}
}

@article{bien2012-22879596,
  author  = {Bien, J. and Jefferson, T. and Causević, M. and Jumpertz, T. and Munter, L. and Multhaup, G. and Weggen, S. and Becker-Pauly, C. and others},
  title   = {{The metalloprotease meprin β generates amino terminal-truncated amyloid β peptide species}},
  journal = {The Journal of biological chemistry},
  year    = {2012},
  doi     = {10.1074/jbc.m112.395608},
  pmid    = {22879596},
  url     = {https://doi.org/10.1074/jbc.m112.395608}
}

@article{samieri2012-22855869,
  author  = {Samieri, C. and Maillard, P. and Crivello, F. and Proust-Lima, C. and Peuchant, E. and Helmer, C. and Amieva, H. and Allard, M. and others},
  title   = {{Plasma long-chain omega-3 fatty acids and atrophy of the medial temporal lobe}},
  journal = {Neurology},
  year    = {2012},
  doi     = {10.1212/wnl.0b013e318264e394},
  pmid    = {22855869},
  url     = {https://doi.org/10.1212/wnl.0b013e318264e394}
}

@article{chenplotkin2012-22895706,
  author  = {Chen-Plotkin, A. S. and Unger, T. L. and Gallagher, M. D. and Bill, E. and Kwong, L. K. and Volpicelli-Daley, L. and Busch, J. I. and Akle, S. and others},
  title   = {{TMEM106B, the risk gene for frontotemporal dementia, is regulated by the microRNA-132/212 cluster and affects progranulin pathways}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2012},
  doi     = {10.1523/jneurosci.0521-12.2012},
  pmid    = {22895706},
  url     = {https://doi.org/10.1523/jneurosci.0521-12.2012}
}

@article{hannestad2012-22776451,
  author  = {Hannestad, J. and Gallezot, J. D. and Schafbauer, T. and Lim, K. and Kloczynski, T. and Morris, E. D. and Carson, R. E. and Ding, Y. S. and others},
  title   = {{Endotoxin-induced systemic inflammation activates microglia: [¹¹C]PBR28 positron emission tomography in nonhuman primates}},
  journal = {NeuroImage},
  year    = {2012},
  doi     = {10.1016/j.neuroimage.2012.06.055},
  pmid    = {22776451},
  url     = {https://doi.org/10.1016/j.neuroimage.2012.06.055}
}

@article{zhou2012-22692213,
  author  = {Zhou, L. and Barão, S. and Laga, M. and Bockstael, K. and Borgers, M. and Gijsen, H. and Annaert, W. and Moechars, D. and others},
  title   = {{The neural cell adhesion molecules L1 and CHL1 are cleaved by BACE1 protease in vivo}},
  journal = {The Journal of biological chemistry},
  year    = {2012},
  doi     = {10.1074/jbc.m112.377465},
  pmid    = {22692213},
  url     = {https://doi.org/10.1074/jbc.m112.377465}
}

@article{wahlberg2012-22655593,
  author  = {Wahlberg, L. U. and Lind, G. and Almqvist, P. M. and Kusk, P. and Tornøe, J. and Juliusson, B. and Söderman, M. and Selldén, E. and others},
  title   = {{Targeted delivery of nerve growth factor via encapsulated cell biodelivery in Alzheimer disease: a technology platform for restorative neurosurgery}},
  journal = {Journal of neurosurgery},
  year    = {2012},
  doi     = {10.3171/2012.2.jns11714},
  pmid    = {22655593},
  url     = {https://doi.org/10.3171/2012.2.jns11714}
}

@article{chami2012-22654105,
  author  = {Chami, L. and Buggia-Prévot, V. and Duplan, E. and Del Prete, D. and Chami, M. and Peyron, J. F. and Checler, F.},
  title   = {{Nuclear factor-κB regulates βAPP and β- and γ-secretases differently at physiological and supraphysiological Aβ concentrations}},
  journal = {The Journal of biological chemistry},
  year    = {2012},
  doi     = {10.1074/jbc.m111.333054},
  pmid    = {22654105},
  url     = {https://doi.org/10.1074/jbc.m111.333054}
}

@article{tweedie2012-22642825,
  author  = {Tweedie, D. and Ferguson, R. A. and Fishman, K. and Frankola, K. A. and Van Praag, H. and Holloway, H. W. and Luo, W. and Li, Y. and others},
  title   = {{Tumor necrosis factor-α synthesis inhibitor 3,6'-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer's disease}},
  journal = {Journal of neuroinflammation},
  year    = {2012},
  doi     = {10.1186/1742-2094-9-106},
  pmid    = {22642825},
  url     = {https://doi.org/10.1186/1742-2094-9-106}
}

@article{linnartz2013-22615186,
  author  = {Linnartz, B. and Neumann, H.},
  title   = {{Microglial activatory (immunoreceptor tyrosine-based activation motif)- and inhibitory (immunoreceptor tyrosine-based inhibition motif)-signaling receptors for recognition of the neuronal glycocalyx}},
  journal = {Glia},
  year    = {2013},
  doi     = {10.1002/glia.22359},
  pmid    = {22615186},
  url     = {https://doi.org/10.1002/glia.22359}
}

@article{bell2012-22622580,
  author  = {Bell, R. D. and Winkler, E. A. and Singh, I. and Sagare, A. P. and Deane, R. and Wu, Z. and Holtzman, D. M. and Betsholtz, C. and others},
  title   = {{Apolipoprotein E controls cerebrovascular integrity via cyclophilin A}},
  journal = {Nature},
  year    = {2012},
  doi     = {10.1038/nature11087},
  pmid    = {22622580},
  url     = {https://doi.org/10.1038/nature11087}
}

@article{xu2012-22537779,
  author  = {Xu, G. and Green, C. C. and Fromholt, S. E. and Borchelt, D. R.},
  title   = {{Reduction of low-density lipoprotein receptor-related protein (LRP1) in hippocampal neurons does not proportionately reduce, or otherwise alter, amyloid deposition in APPswe/PS1dE9 transgenic mice}},
  journal = {Alzheimer's research \& therapy},
  year    = {2012},
  doi     = {10.1186/alzrt110},
  pmid    = {22537779},
  url     = {https://doi.org/10.1186/alzrt110}
}

@article{xiao2012-22539346,
  author  = {Xiao, Q. and Gil, S. C. and Yan, P. and Wang, Y. and Han, S. and Gonzales, E. and Perez, R. and Cirrito, JR. and others},
  title   = {{Role of phosphatidylinositol clathrin assembly lymphoid-myeloid leukemia (PICALM) in intracellular amyloid precursor protein (APP) processing and amyloid plaque pathogenesis}},
  journal = {The Journal of biological chemistry},
  year    = {2012},
  doi     = {10.1074/jbc.m111.338376},
  pmid    = {22539346},
  url     = {https://doi.org/10.1074/jbc.m111.338376}
}

@article{vedin2012-22545106,
  author  = {Vedin, I. and Cederholm, T. and Freund-Levi, Y. and Basun, H. and Garlind, A. and Irving, G. F. and Eriksdotter-Jönhagen, M. and Wahlund, L. O. and others},
  title   = {{Effects of DHA-rich n-3 fatty acid supplementation on gene expression in blood mononuclear leukocytes: the OmegAD study}},
  journal = {PloS one},
  year    = {2012},
  doi     = {10.1371/journal.pone.0035425},
  pmid    = {22545106},
  url     = {https://doi.org/10.1371/journal.pone.0035425}
}

@article{gao2012-22503440,
  author  = {Gao, H. M. and Zhou, H. and Hong, J. S.},
  title   = {{NADPH oxidases: novel therapeutic targets for neurodegenerative diseases}},
  journal = {Trends in pharmacological sciences},
  year    = {2012},
  doi     = {10.1016/j.tips.2012.03.008},
  pmid    = {22503440},
  url     = {https://doi.org/10.1016/j.tips.2012.03.008}
}

@article{peng2012-22516463,
  author  = {Peng, J. and Liang, G. and Inan, S. and Wu, Z. and Joseph, D. J. and Meng, Q. and Peng, Y. and Eckenhoff, M. F. and others},
  title   = {{Dantrolene ameliorates cognitive decline and neuropathology in Alzheimer triple transgenic mice}},
  journal = {Neuroscience letters},
  year    = {2012},
  doi     = {10.1016/j.neulet.2012.04.008},
  pmid    = {22516463},
  url     = {https://doi.org/10.1016/j.neulet.2012.04.008}
}

@article{congdon2012-22361619,
  author  = {Congdon, E. E. and Wu, J. W. and Myeku, N. and Figueroa, Y. H. and Herman, M. and Marinec, P. S. and Gestwicki, J. E. and Dickey, C. A. and others},
  title   = {{Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo}},
  journal = {Autophagy},
  year    = {2012},
  doi     = {10.4161/auto.19048},
  pmid    = {22361619},
  url     = {https://doi.org/10.4161/auto.19048}
}

@article{colombrita2012-22427648,
  author  = {Colombrita, C. and Onesto, E. and Megiorni, F. and Pizzuti, A. and Baralle, F. E. and Buratti, E. and Silani, V. and Ratti, A.},
  title   = {{TDP-43 and FUS RNA-binding proteins bind distinct sets of cytoplasmic messenger RNAs and differently regulate their post-transcriptional fate in motoneuron-like cells}},
  journal = {The Journal of biological chemistry},
  year    = {2012},
  doi     = {10.1074/jbc.m111.333450},
  pmid    = {22427648},
  url     = {https://doi.org/10.1074/jbc.m111.333450}
}

@article{fisette2012-22303960,
  author  = {Fisette, J. F. and Montagna, D. R. and Mihailescu, M. R. and Wolfe, M. S.},
  title   = {{A G-rich element forms a G-quadruplex and regulates BACE1 mRNA alternative splicing}},
  journal = {Journal of neurochemistry},
  year    = {2012},
  doi     = {10.1111/j.1471-4159.2012.07680.x},
  pmid    = {22303960},
  url     = {https://doi.org/10.1111/j.1471-4159.2012.07680.x}
}

@article{frodl2012-22832853,
  author  = {Frodl, T. and Carballedo, A. and Hughes, M. M. and Saleh, K. and Fagan, A. and Skokauskas, N. and McLoughlin, D. M. and Meaney, J. and others},
  title   = {{Reduced expression of glucocorticoid-inducible genes GILZ and SGK-1: high IL-6 levels are associated with reduced hippocampal volumes in major depressive disorder}},
  journal = {Translational psychiatry},
  year    = {2012},
  doi     = {10.1038/tp.2012.14},
  pmid    = {22832853},
  url     = {https://doi.org/10.1038/tp.2012.14}
}

@article{majounie2012-22406228,
  author  = {Majounie, E. and Renton, A. E. and Mok, K. and Dopper, E. G. and Waite, A. and Rollinson, S. and Chiò, A. and Restagno, G. and others},
  title   = {{Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study}},
  journal = {The Lancet. Neurology},
  year    = {2012},
  doi     = {10.1016/s1474-4422(12)70043-1},
  pmid    = {22406228},
  url     = {https://doi.org/10.1016/s1474-4422(12)70043-1}
}

@article{javed2012-22441036,
  author  = {Javed, H. and Khan, M. M. and Ahmad, A. and Vaibhav, K. and Ahmad, M. E. and Khan, A. and Ashafaq, M. and Islam, F. and others},
  title   = {{Rutin prevents cognitive impairments by ameliorating oxidative stress and neuroinflammation in rat model of sporadic dementia of Alzheimer type}},
  journal = {Neuroscience},
  year    = {2012},
  doi     = {10.1016/j.neuroscience.2012.02.046},
  pmid    = {22441036},
  url     = {https://doi.org/10.1016/j.neuroscience.2012.02.046}
}

@article{ono2012-22393064,
  author  = {Ono, K. and Li, L. and Takamura, Y. and Yoshiike, Y. and Zhu, L. and Han, F. and Mao, X. and Ikeda, T. and others},
  title   = {{Phenolic compounds prevent amyloid β-protein oligomerization and synaptic dysfunction by site-specific binding}},
  journal = {The Journal of biological chemistry},
  year    = {2012},
  doi     = {10.1074/jbc.m111.325456},
  pmid    = {22393064},
  url     = {https://doi.org/10.1074/jbc.m111.325456}
}

@article{basak2012-22383525,
  author  = {Basak, J. M. and Verghese, P. B. and Yoon, H. and Kim, J. and Holtzman, D. M.},
  title   = {{Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Aβ uptake and degradation by astrocytes}},
  journal = {The Journal of biological chemistry},
  year    = {2012},
  doi     = {10.1074/jbc.m111.288746},
  pmid    = {22383525},
  url     = {https://doi.org/10.1074/jbc.m111.288746}
}

@article{lee2012-22339795,
  author  = {Lee, Y. J. and Choi, D. Y. and Choi, I. S. and Kim, K. H. and Kim, Y. H. and Kim, H. M. and Lee, K. and Cho, W. G. and others},
  title   = {{Inhibitory effect of 4-O-methylhonokiol on lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment via inhibition of nuclear factor-kappaB in vitro and in vivo models}},
  journal = {Journal of neuroinflammation},
  year    = {2012},
  doi     = {10.1186/1742-2094-9-35},
  pmid    = {22339795},
  url     = {https://doi.org/10.1186/1742-2094-9-35}
}

@article{winkelmann2012-22328086,
  author  = {Winkelmann, J. and Lin, L. and Schormair, B. and Kornum, B. R. and Faraco, J. and Plazzi, G. and Melberg, A. and Cornelio, F. and others},
  title   = {{Mutations in DNMT1 cause autosomal dominant cerebellar ataxia, deafness and narcolepsy}},
  journal = {Human molecular genetics},
  year    = {2012},
  doi     = {10.1093/hmg/dds035},
  pmid    = {22328086},
  url     = {https://doi.org/10.1093/hmg/dds035}
}

@article{kawahara2012-22323604,
  author  = {Kawahara, Y. and Mieda-Sato, A.},
  title   = {{TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2012},
  doi     = {10.1073/pnas.1112427109},
  pmid    = {22323604},
  url     = {https://doi.org/10.1073/pnas.1112427109}
}

@article{yuyama2012-22303002,
  author  = {Yuyama, K. and Sun, H. and Mitsutake, S. and Igarashi, Y.},
  title   = {{Sphingolipid-modulated exosome secretion promotes clearance of amyloid-β by microglia}},
  journal = {The Journal of biological chemistry},
  year    = {2012},
  doi     = {10.1074/jbc.m111.324616},
  pmid    = {22303002},
  url     = {https://doi.org/10.1074/jbc.m111.324616}
}

@article{tran2012-22249463,
  author  = {Tran, H. T. and Sanchez, L. and Brody, D. L.},
  title   = {{Inhibition of JNK by a peptide inhibitor reduces traumatic brain injury-induced tauopathy in transgenic mice}},
  journal = {Journal of neuropathology and experimental neurology},
  year    = {2012},
  doi     = {10.1097/nen.0b013e3182456aed},
  pmid    = {22249463},
  url     = {https://doi.org/10.1097/nen.0b013e3182456aed}
}

@article{parker2012-22306778,
  author  = {Parker, S. J. and Meyerowitz, J. and James, J. L. and Liddell, JR. and Crouch, P. J. and Kanninen, K. M. and White, A. R.},
  title   = {{Endogenous TDP-43 localized to stress granules can subsequently form protein aggregates}},
  journal = {Neurochemistry international},
  year    = {2012},
  doi     = {10.1016/j.neuint.2012.01.019},
  pmid    = {22306778},
  url     = {https://doi.org/10.1016/j.neuint.2012.01.019}
}

@article{king2012-22445064,
  author  = {King, O. D. and Gitler, A. D. and Shorter, J.},
  title   = {{The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease}},
  journal = {Brain research},
  year    = {2012},
  doi     = {10.1016/j.brainres.2012.01.016},
  pmid    = {22445064},
  url     = {https://doi.org/10.1016/j.brainres.2012.01.016}
}

@article{fuso2012-22221883,
  author  = {Fuso, A. and Nicolia, V. and Ricceri, L. and Cavallaro, R. A. and Isopi, E. and Mangia, F. and Fiorenza, M. T. and Scarpa, S.},
  title   = {{S-adenosylmethionine reduces the progress of the Alzheimer-like features induced by B-vitamin deficiency in mice}},
  journal = {Neurobiology of aging},
  year    = {2012},
  doi     = {10.1016/j.neurobiolaging.2011.12.013},
  pmid    = {22221883},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2011.12.013}
}

@article{mori2012-22219198,
  author  = {Mori, T. and Rezai-Zadeh, K. and Koyama, N. and Arendash, G. W. and Yamaguchi, H. and Kakuda, N. and Horikoshi-Sakuraba, Y. and Tan, J. and others},
  title   = {{Tannic acid is a natural β-secretase inhibitor that prevents cognitive impairment and mitigates Alzheimer-like pathology in transgenic mice}},
  journal = {The Journal of biological chemistry},
  year    = {2012},
  doi     = {10.1074/jbc.m111.294025},
  pmid    = {22219198},
  url     = {https://doi.org/10.1074/jbc.m111.294025}
}

@article{choi2012-22354138,
  author  = {Choi, SR. and Schneider, J. A. and Bennett, D. A. and Beach, T. G. and Bedell, B. J. and Zehntner, S. P. and Krautkramer, M. J. and Kung, H. F. and others},
  title   = {{Correlation of amyloid PET ligand florbetapir F 18 binding with Aβ aggregation and neuritic plaque deposition in postmortem brain tissue}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2012},
  doi     = {10.1097/wad.0b013e31821300bc},
  pmid    = {22354138},
  url     = {https://doi.org/10.1097/wad.0b013e31821300bc}
}

@article{carter2012-22213821,
  author  = {Carter, S. F. and Schöll, M. and Almkvist, O. and Wall, A. and Engler, H. and Långström, B. and Nordberg, A.},
  title   = {{Evidence for astrocytosis in prodromal Alzheimer disease provided by 11C-deuterium-L-deprenyl: a multitracer PET paradigm combining 11C-Pittsburgh compound B and 18F-FDG}},
  journal = {Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year    = {2012},
  doi     = {10.2967/jnumed.110.087031},
  pmid    = {22213821},
  url     = {https://doi.org/10.2967/jnumed.110.087031}
}

@article{brettschneider2012-22210083,
  author  = {Brettschneider, J. and Libon, D. J. and Toledo, J. B. and Xie, S. X. and McCluskey, L. and Elman, L. and Geser, F. and Lee, V. M. and others},
  title   = {{Microglial activation and TDP-43 pathology correlate with executive dysfunction in amyotrophic lateral sclerosis}},
  journal = {Acta neuropathologica},
  year    = {2012},
  doi     = {10.1007/s00401-011-0932-x},
  pmid    = {22210083},
  url     = {https://doi.org/10.1007/s00401-011-0932-x}
}

@article{poli2012-22453180,
  author  = {Poli, G. and Corda, E. and Lucchini, B. and Puricelli, M. and Martino, P. A. and Dall'ara, P. and Villetti, G. and Bareggi, SR. and others},
  title   = {{Therapeutic effect of CHF5074, a new γ-secretase modulator, in a mouse model of scrapie}},
  journal = {Prion},
  year    = {2012},
  doi     = {10.4161/pri.6.1.18317},
  pmid    = {22453180},
  url     = {https://doi.org/10.4161/pri.6.1.18317}
}

@article{yu2012-22156579,
  author  = {Yu, W. and Polepalli, J. and Wagh, D. and Rajadas, J. and Malenka, R. and Lu, B.},
  title   = {{A critical role for the PAR-1/MARK-tau axis in mediating the toxic effects of Aβ on synapses and dendritic spines}},
  journal = {Human molecular genetics},
  year    = {2012},
  doi     = {10.1093/hmg/ddr576},
  pmid    = {22156579},
  url     = {https://doi.org/10.1093/hmg/ddr576}
}

@article{young2012-22155432,
  author  = {Young, F. B. and Butland, S. L. and Sanders, S. S. and Sutton, L. M. and Hayden, M. R.},
  title   = {{Putting proteins in their place: palmitoylation in Huntington disease and other neuropsychiatric diseases}},
  journal = {Progress in neurobiology},
  year    = {2012},
  doi     = {10.1016/j.pneurobio.2011.11.002},
  pmid    = {22155432},
  url     = {https://doi.org/10.1016/j.pneurobio.2011.11.002}
}

@article{murray2011-22083254,
  author  = {Murray, M. E. and DeJesus-Hernandez, M. and Rutherford, N. J. and Baker, M. and Duara, R. and Graff-Radford, N. R. and Wszolek, Z. K. and Ferman, T. J. and others},
  title   = {{Clinical and neuropathologic heterogeneity of c9FTD/ALS associated with hexanucleotide repeat expansion in C9ORF72}},
  journal = {Acta neuropathologica},
  year    = {2011},
  doi     = {10.1007/s00401-011-0907-y},
  pmid    = {22083254},
  url     = {https://doi.org/10.1007/s00401-011-0907-y}
}

@article{li2012-22115895,
  author  = {Li, L. and Zhang, Z. F. and Holscher, C. and Gao, C. and Jiang, Y. H. and Liu, Y. Z.},
  title   = {{(Val⁸) glucagon-like peptide-1 prevents tau hyperphosphorylation, impairment of spatial learning and ultra-structural cellular damage induced by streptozotocin in rat brains}},
  journal = {European journal of pharmacology},
  year    = {2012},
  doi     = {10.1016/j.ejphar.2011.11.005},
  pmid    = {22115895},
  url     = {https://doi.org/10.1016/j.ejphar.2011.11.005}
}

@article{murakami2011-22072713,
  author  = {Murakami, K. and Murata, N. and Noda, Y. and Tahara, S. and Kaneko, T. and Kinoshita, N. and Hatsuta, H. and Murayama, S. and others},
  title   = {{SOD1 (copper/zinc superoxide dismutase) deficiency drives amyloid β protein oligomerization and memory loss in mouse model of Alzheimer disease}},
  journal = {The Journal of biological chemistry},
  year    = {2011},
  doi     = {10.1074/jbc.m111.279208},
  pmid    = {22072713},
  url     = {https://doi.org/10.1074/jbc.m111.279208}
}

@article{sclip2011-22033930,
  author  = {Sclip, A. and Antoniou, X. and Colombo, A. and Camici, G. G. and Pozzi, L. and Cardinetti, D. and Feligioni, M. and Veglianese, P. and others},
  title   = {{c-Jun N-terminal kinase regulates soluble Aβ oligomers and cognitive impairment in AD mouse model}},
  journal = {The Journal of biological chemistry},
  year    = {2011},
  doi     = {10.1074/jbc.m111.297515},
  pmid    = {22033930},
  url     = {https://doi.org/10.1074/jbc.m111.297515}
}

@article{ljungberg2012-22027994,
  author  = {Ljungberg, M. C. and Ali, Y. O. and Zhu, J. and Wu, C. S. and Oka, K. and Zhai, R. G. and Lu, H. C.},
  title   = {{CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy}},
  journal = {Human molecular genetics},
  year    = {2012},
  doi     = {10.1093/hmg/ddr492},
  pmid    = {22027994},
  url     = {https://doi.org/10.1093/hmg/ddr492}
}

@article{petkau2012-22062772,
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  title   = {{Synaptic dysfunction in progranulin-deficient mice}},
  journal = {Neurobiology of disease},
  year    = {2012},
  doi     = {10.1016/j.nbd.2011.10.016},
  pmid    = {22062772},
  url     = {https://doi.org/10.1016/j.nbd.2011.10.016}
}

@article{volpicellidaley2011-21982369,
  author  = {Volpicelli-Daley, L. A. and Luk, K. C. and Patel, T. P. and Tanik, S. A. and Riddle, D. M. and Stieber, A. and Meaney, D. F. and Trojanowski, J. Q. and others},
  title   = {{Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death}},
  journal = {Neuron},
  year    = {2011},
  doi     = {10.1016/j.neuron.2011.08.033},
  pmid    = {21982369},
  url     = {https://doi.org/10.1016/j.neuron.2011.08.033}
}

@article{ali2012-21965302,
  author  = {Ali, Y. O. and Ruan, K. and Zhai, R. G.},
  title   = {{NMNAT suppresses tau-induced neurodegeneration by promoting clearance of hyperphosphorylated tau oligomers in a Drosophila model of tauopathy}},
  journal = {Human molecular genetics},
  year    = {2012},
  doi     = {10.1093/hmg/ddr449},
  pmid    = {21965302},
  url     = {https://doi.org/10.1093/hmg/ddr449}
}

@article{jung2011-21965663,
  author  = {Jung, M. S. and Park, J. H. and Ryu, Y. S. and Choi, S. H. and Yoon, S. H. and Kwen, M. Y. and Oh, J. Y. and Song, W. J. and others},
  title   = {{Regulation of RCAN1 protein activity by Dyrk1A protein-mediated phosphorylation}},
  journal = {The Journal of biological chemistry},
  year    = {2011},
  doi     = {10.1074/jbc.m111.253971},
  pmid    = {21965663},
  url     = {https://doi.org/10.1074/jbc.m111.253971}
}

@article{reese2011-21883216,
  author  = {Reese, L. C. and Laezza, F. and Woltjer, R. and Taglialatela, G.},
  title   = {{Dysregulated phosphorylation of Ca(2+) /calmodulin-dependent protein kinase II-α in the hippocampus of subjects with mild cognitive impairment and Alzheimer's disease}},
  journal = {Journal of neurochemistry},
  year    = {2011},
  doi     = {10.1111/j.1471-4159.2011.07447.x},
  pmid    = {21883216},
  url     = {https://doi.org/10.1111/j.1471-4159.2011.07447.x}
}

@article{renton2011-21944779,
  author  = {Renton, A. E. and Majounie, E. and Waite, A. and Simón-Sánchez, J. and Rollinson, S. and Gibbs, JR. and Schymick, J. C. and Laaksovirta, H. and others},
  title   = {{A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD}},
  journal = {Neuron},
  year    = {2011},
  doi     = {10.1016/j.neuron.2011.09.010},
  pmid    = {21944779},
  url     = {https://doi.org/10.1016/j.neuron.2011.09.010}
}

@article{dejesushernandez2011-21944778,
  author  = {DeJesus-Hernandez, M. and Mackenzie, I. R. and Boeve, B. F. and Boxer, A. L. and Baker, M. and Rutherford, N. J. and Nicholson, A. M. and Finch, N. A. and others},
  title   = {{Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS}},
  journal = {Neuron},
  year    = {2011},
  doi     = {10.1016/j.neuron.2011.09.011},
  pmid    = {21944778},
  url     = {https://doi.org/10.1016/j.neuron.2011.09.011}
}

@article{neniskyte2011-21903584,
  author  = {Neniskyte, U. and Neher, J. J. and Brown, G. C.},
  title   = {{Neuronal death induced by nanomolar amyloid β is mediated by primary phagocytosis of neurons by microglia}},
  journal = {The Journal of biological chemistry},
  year    = {2011},
  doi     = {10.1074/jbc.m111.267583},
  pmid    = {21903584},
  url     = {https://doi.org/10.1074/jbc.m111.267583}
}

@article{dacruz2011-21813273,
  author  = {Da Cruz, S. and Cleveland, D. W.},
  title   = {{Understanding the role of TDP-43 and FUS/TLS in ALS and beyond}},
  journal = {Current opinion in neurobiology},
  year    = {2011},
  doi     = {10.1016/j.conb.2011.05.029},
  pmid    = {21813273},
  url     = {https://doi.org/10.1016/j.conb.2011.05.029}
}

@article{stlaurentthibault2011-21605049,
  author  = {St-Laurent-Thibault, C. and Arseneault, M. and Longpré, F. and Ramassamy, C.},
  title   = {{Tyrosol and hydroxytyrosol, two main components of olive oil, protect N2a cells against amyloid-β-induced toxicity. Involvement of the NF-κB signaling}},
  journal = {Current Alzheimer research},
  year    = {2011},
  doi     = {10.2174/156720511796391845},
  pmid    = {21605049},
  url     = {https://doi.org/10.2174/156720511796391845}
}

@article{paolicelli2011-21778362,
  author  = {Paolicelli, Rosa Chiara and Bolasco, Giulia and Pagani, Francesca and Maggi, Laura and Scianni, Maria and Panzanelli, Patrizia and Giustetto, Maurizio and Ferreira, Tiago and Guiducci, Eva and Dumas, Laura and Ragozzino, Davide and Gross, Cornelius Thilo},
  title   = {{Synaptic Pruning by Microglia Is Necessary for Normal Brain Development}},
  journal = {Science},
  year    = {2011},
  doi     = {10.1126/science.1202529},
  pmid    = {21778362},
  url     = {https://doi.org/10.1126/science.1202529}
}

@article{cho2011-21771791,
  author  = {Cho, S. H. and Sun, B. and Zhou, Y. and Kauppinen, T. M. and Halabisky, B. and Wes, P. and Ransohoff, R. M. and Gan, L.},
  title   = {{CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease}},
  journal = {The Journal of biological chemistry},
  year    = {2011},
  doi     = {10.1074/jbc.m111.254268},
  pmid    = {21771791},
  url     = {https://doi.org/10.1074/jbc.m111.254268}
}

@article{kobayashi2011-21683323,
  author  = {Kobayashi, H. and Abe, K. and Matsuura, T. and Ikeda, Y. and Hitomi, T. and Akechi, Y. and Habu, T. and Liu, W. and others},
  title   = {{Expansion of intronic GGCCTG hexanucleotide repeat in NOP56 causes SCA36, a type of spinocerebellar ataxia accompanied by motor neuron involvement}},
  journal = {American journal of human genetics},
  year    = {2011},
  doi     = {10.1016/j.ajhg.2011.05.015},
  pmid    = {21683323},
  url     = {https://doi.org/10.1016/j.ajhg.2011.05.015}
}

@article{ginsberg2011-21669283,
  author  = {Ginsberg, S. D. and Mufson, E. J. and Alldred, M. J. and Counts, S. E. and Wuu, J. and Nixon, R. A. and Che, S.},
  title   = {{Upregulation of select rab GTPases in cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease}},
  journal = {Journal of chemical neuroanatomy},
  year    = {2011},
  doi     = {10.1016/j.jchemneu.2011.05.012},
  pmid    = {21669283},
  url     = {https://doi.org/10.1016/j.jchemneu.2011.05.012}
}

@article{minanomolina2011-21665950,
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  title   = {{Soluble oligomers of amyloid-β peptide disrupt membrane trafficking of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor contributing to early synapse dysfunction}},
  journal = {The Journal of biological chemistry},
  year    = {2011},
  doi     = {10.1074/jbc.m111.227504},
  pmid    = {21665950},
  url     = {https://doi.org/10.1074/jbc.m111.227504}
}

@article{masliah2011-21559417,
  author  = {Masliah, E. and Rockenstein, E. and Mante, M. and Crews, L. and Spencer, B. and Adame, A. and Patrick, C. and Trejo, M. and others},
  title   = {{Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease}},
  journal = {PloS one},
  year    = {2011},
  doi     = {10.1371/journal.pone.0019338},
  pmid    = {21559417},
  url     = {https://doi.org/10.1371/journal.pone.0019338}
}

@article{weyer2011-21522131,
  author  = {Weyer, S. W. and Klevanski, M. and Delekate, A. and Voikar, V. and Aydin, D. and Hick, M. and Filippov, M. and Drost, N. and others},
  title   = {{APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP}},
  journal = {The EMBO journal},
  year    = {2011},
  doi     = {10.1038/emboj.2011.119},
  pmid    = {21522131},
  url     = {https://doi.org/10.1038/emboj.2011.119}
}

@article{sun2011-21541367,
  author  = {Sun, Z. and Diaz, Z. and Fang, X. and Hart, M. P. and Chesi, A. and Shorter, J. and Gitler, A. D.},
  title   = {{Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS}},
  journal = {PLoS biology},
  year    = {2011},
  doi     = {10.1371/journal.pbio.1000614},
  pmid    = {21541367},
  url     = {https://doi.org/10.1371/journal.pbio.1000614}
}

@article{nishitsuji2011-21471207,
  author  = {Nishitsuji, K. and Hosono, T. and Nakamura, T. and Bu, G. and Michikawa, M.},
  title   = {{Apolipoprotein E regulates the integrity of tight junctions in an isoform-dependent manner in an in vitro blood-brain barrier model}},
  journal = {The Journal of biological chemistry},
  year    = {2011},
  doi     = {10.1074/jbc.m111.225532},
  pmid    = {21471207},
  url     = {https://doi.org/10.1074/jbc.m111.225532}
}

@article{kohli2011-21521612,
  author  = {Kohli, M. A. and Lucae, S. and Saemann, P. G. and Schmidt, M. V. and Demirkan, A. and Hek, K. and Czamara, D. and Alexander, M. and others},
  title   = {{The neuronal transporter gene SLC6A15 confers risk to major depression}},
  journal = {Neuron},
  year    = {2011},
  doi     = {10.1016/j.neuron.2011.04.005},
  pmid    = {21521612},
  url     = {https://doi.org/10.1016/j.neuron.2011.04.005}
}

@article{brodbeck2011-21454574,
  author  = {Brodbeck, J. and McGuire, J. and Liu, Z. and Meyer-Franke, A. and Balestra, M. E. and Jeong, D. E. and Pleiss, M. and McComas, C. and others},
  title   = {{Structure-dependent impairment of intracellular apolipoprotein E4 trafficking and its detrimental effects are rescued by small-molecule structure correctors}},
  journal = {The Journal of biological chemistry},
  year    = {2011},
  doi     = {10.1074/jbc.m110.217380},
  pmid    = {21454574},
  url     = {https://doi.org/10.1074/jbc.m110.217380}
}

@article{tollervey2011-21358640,
  author  = {Tollervey, JR. and Curk, T. and Rogelj, B. and Briese, M. and Cereda, M. and Kayikci, M. and König, J. and Hortobágyi, T. and others},
  title   = {{Characterizing the RNA targets and position-dependent splicing regulation by TDP-43}},
  journal = {Nature neuroscience},
  year    = {2011},
  doi     = {10.1038/nn.2778},
  pmid    = {21358640},
  url     = {https://doi.org/10.1038/nn.2778}
}

@article{polymenidou2011-21358643,
  author  = {Polymenidou, Magdalini and Lagier‐Tourenne, Clotilde and Hutt, Kasey R. and Huelga, Stephanie C. and Moran, Jacqueline and Liang, Tiffany Y and Ling, Shuo‐Chien and Sun, Eveline and Wancewicz, Edward V. and Mazur, Curt and Kordasiewicz, Holly B. and Sedaghat, Yalda and Donohue, John Paul and Shiue, Lily and Bennett, C. Frank and Yeo, Gene Wei-Ming and Cleveland, Don W.},
  title   = {{Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43}},
  journal = {Nature Neuroscience},
  year    = {2011},
  doi     = {10.1038/nn.2779},
  pmid    = {21358643},
  url     = {https://doi.org/10.1038/nn.2779}
}

@article{schjeide2011-21300948,
  author  = {Schjeide, B. M. and Schnack, C. and Lambert, J. C. and Lill, C. M. and Kirchheiner, J. and Tumani, H. and Otto, M. and Tanzi, R. E. and others},
  title   = {{The role of clusterin, complement receptor 1, and phosphatidylinositol binding clathrin assembly protein in Alzheimer disease risk and cerebrospinal fluid biomarker levels}},
  journal = {Archives of general psychiatry},
  year    = {2011},
  doi     = {10.1001/archgenpsychiatry.2010.196},
  pmid    = {21300948},
  url     = {https://doi.org/10.1001/archgenpsychiatry.2010.196}
}

@article{pabon2011-21266082,
  author  = {Pabon, M. M. and Bachstetter, A. D. and Hudson, C. E. and Gemma, C. and Bickford, P. C.},
  title   = {{CX3CL1 reduces neurotoxicity and microglial activation in a rat model of Parkinson's disease}},
  journal = {Journal of neuroinflammation},
  year    = {2011},
  doi     = {10.1186/1742-2094-8-9},
  pmid    = {21266082},
  url     = {https://doi.org/10.1186/1742-2094-8-9}
}

@article{caccamo2011-21266573,
  author  = {Caccamo, A. and Maldonado, M. A. and Majumder, S. and Medina, D. X. and Holbein, W. and Magrí, A. and Oddo, S.},
  title   = {{Naturally secreted amyloid-beta increases mammalian target of rapamycin (mTOR) activity via a PRAS40-mediated mechanism}},
  journal = {The Journal of biological chemistry},
  year    = {2011},
  doi     = {10.1074/jbc.m110.180638},
  pmid    = {21266573},
  url     = {https://doi.org/10.1074/jbc.m110.180638}
}

@article{lu2011-21252229,
  author  = {Lu, M. and Zheng, L. and Han, B. and Wang, L. and Wang, P. and Liu, H. and Sun, X.},
  title   = {{REST regulates DYRK1A transcription in a negative feedback loop}},
  journal = {The Journal of biological chemistry},
  year    = {2011},
  doi     = {10.1074/jbc.m110.174540},
  pmid    = {21252229},
  url     = {https://doi.org/10.1074/jbc.m110.174540}
}

@article{sun2011-21216952,
  author  = {Sun, X. and Wu, Y. and Chen, B. and Zhang, Z. and Zhou, W. and Tong, Y. and Yuan, J. and Xia, K. and others},
  title   = {{Regulator of calcineurin 1 (RCAN1) facilitates neuronal apoptosis through caspase-3 activation}},
  journal = {The Journal of biological chemistry},
  year    = {2011},
  doi     = {10.1074/jbc.m110.177519},
  pmid    = {21216952},
  url     = {https://doi.org/10.1074/jbc.m110.177519}
}

@article{igaz2011-21206091,
  author  = {Igaz, L. M. and Kwong, L. K. and Lee, E. B. and Chen-Plotkin, A. and Swanson, E. and Unger, T. and Malunda, J. and Xu, Y. and others},
  title   = {{Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice}},
  journal = {The Journal of clinical investigation},
  year    = {2011},
  doi     = {10.1172/jci44867},
  pmid    = {21206091},
  url     = {https://doi.org/10.1172/jci44867}
}

@article{hongpaisan2011-21228172,
  author  = {Hongpaisan, J. and Sun, M. K. and Alkon, D. L.},
  title   = {{PKC ε activation prevents synaptic loss, Aβ elevation, and cognitive deficits in Alzheimer's disease transgenic mice}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2011},
  doi     = {10.1523/jneurosci.5209-10.2011},
  pmid    = {21228172},
  url     = {https://doi.org/10.1523/jneurosci.5209-10.2011}
}

@article{mandel2011-21368374,
  author  = {Mandel, S. A. and Amit, T. and Weinreb, O. and Youdim, M. B.},
  title   = {{Understanding the broad-spectrum neuroprotective action profile of green tea polyphenols in aging and neurodegenerative diseases}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2011},
  doi     = {10.3233/jad-2011-101803},
  pmid    = {21368374},
  url     = {https://doi.org/10.3233/jad-2011-101803}
}

@article{murakami2011-21558647,
  author  = {Murakami, K. and Murata, N. and Ozawa, Y. and Kinoshita, N. and Irie, K. and Shirasawa, T. and Shimizu, T.},
  title   = {{Vitamin C restores behavioral deficits and amyloid-β oligomerization without affecting plaque formation in a mouse model of Alzheimer's disease}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2011},
  doi     = {10.3233/jad-2011-101971},
  pmid    = {21558647},
  url     = {https://doi.org/10.3233/jad-2011-101971}
}

@article{dewey2011-21173160,
  author  = {Dewey, C. M. and Cenik, B. and Sephton, C. F. and Dries, D. R. and Mayer, P. and Good, S. K. and Johnson, B. A. and Herz, J. and others},
  title   = {{TDP-43 is directed to stress granules by sorbitol, a novel physiological osmotic and oxidative stressor}},
  journal = {Molecular and cellular biology},
  year    = {2011},
  doi     = {10.1128/mcb.01279-10},
  pmid    = {21173160},
  url     = {https://doi.org/10.1128/mcb.01279-10}
}

@article{damelio2011-21151119,
  author  = {D'Amelio, M. and Cavallucci, V. and Middei, S. and Marchetti, C. and Pacioni, S. and Ferri, A. and Diamantini, A. and De Zio, D. and others},
  title   = {{Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease}},
  journal = {Nature neuroscience},
  year    = {2011},
  doi     = {10.1038/nn.2709},
  pmid    = {21151119},
  url     = {https://doi.org/10.1038/nn.2709}
}

@article{ayala2011-21131904,
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  title   = {{TDP-43 regulates its mRNA levels through a negative feedback loop}},
  journal = {The EMBO journal},
  year    = {2011},
  doi     = {10.1038/emboj.2010.310},
  pmid    = {21131904},
  url     = {https://doi.org/10.1038/emboj.2010.310}
}

@article{austin2010-21127294,
  author  = {Austin, S. A. and Santhanam, A. V. and Katusic, Z. S.},
  title   = {{Endothelial nitric oxide modulates expression and processing of amyloid precursor protein}},
  journal = {Circulation research},
  year    = {2010},
  doi     = {10.1161/circresaha.110.233080},
  pmid    = {21127294},
  url     = {https://doi.org/10.1161/circresaha.110.233080}
}

@article{bot2011-21084300,
  author  = {Bot, N. and Schweizer, C. and Ben Halima, S. and Fraering, P. C.},
  title   = {{Processing of the synaptic cell adhesion molecule neurexin-3beta by Alzheimer disease alpha- and gamma-secretases}},
  journal = {The Journal of biological chemistry},
  year    = {2011},
  doi     = {10.1074/jbc.m110.142521},
  pmid    = {21084300},
  url     = {https://doi.org/10.1074/jbc.m110.142521}
}

@article{delarasse2011-21081501,
  author  = {Delarasse, C. and Auger, R. and Gonnord, P. and Fontaine, B. and Kanellopoulos, J. M.},
  title   = {{The purinergic receptor P2X7 triggers alpha-secretase-dependent processing of the amyloid precursor protein}},
  journal = {The Journal of biological chemistry},
  year    = {2011},
  doi     = {10.1074/jbc.m110.200618},
  pmid    = {21081501},
  url     = {https://doi.org/10.1074/jbc.m110.200618}
}

@article{thanopoulou2010-21076037,
  author  = {Thanopoulou, K. and Fragkouli, A. and Stylianopoulou, F. and Georgopoulos, S.},
  title   = {{Scavenger receptor class B type I (SR-BI) regulates perivascular macrophages and modifies amyloid pathology in an Alzheimer mouse model}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2010},
  doi     = {10.1073/pnas.1005888107},
  pmid    = {21076037},
  url     = {https://doi.org/10.1073/pnas.1005888107}
}

@article{ricobaraza2012-21069780,
  author  = {Ricobaraza, A. and Cuadrado-Tejedor, M. and Marco, S. and Pérez-Otaño, I. and García-Osta, A.},
  title   = {{Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease}},
  journal = {Hippocampus},
  year    = {2012},
  doi     = {10.1002/hipo.20883},
  pmid    = {21069780},
  url     = {https://doi.org/10.1002/hipo.20883}
}

@article{oleary2010-21040568,
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  title   = {{Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden}},
  journal = {Molecular neurodegeneration},
  year    = {2010},
  doi     = {10.1186/1750-1326-5-45},
  pmid    = {21040568},
  url     = {https://doi.org/10.1186/1750-1326-5-45}
}

@article{hu2010-21092856,
  author  = {Hu, F. and Padukkavidana, T. and Vægter, C. B. and Brady, O. A. and Zheng, Y. and Mackenzie, I. R. and Feldman, H. H. and Nykjaer, A. and others},
  title   = {{Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin}},
  journal = {Neuron},
  year    = {2010},
  doi     = {10.1016/j.neuron.2010.09.034},
  pmid    = {21092856},
  url     = {https://doi.org/10.1016/j.neuron.2010.09.034}
}

@article{maezawa2011-20971854,
  author  = {Maezawa, I. and Zimin, P. I. and Wulff, H. and Jin, L. W.},
  title   = {{Amyloid-beta protein oligomer at low nanomolar concentrations activates microglia and induces microglial neurotoxicity}},
  journal = {The Journal of biological chemistry},
  year    = {2011},
  doi     = {10.1074/jbc.m110.135244},
  pmid    = {20971854},
  url     = {https://doi.org/10.1074/jbc.m110.135244}
}

@article{takata2010-20947502,
  author  = {Takata, K. and Kitamura, Y. and Saeki, M. and Terada, M. and Kagitani, S. and Kitamura, R. and Fujikawa, Y. and Maelicke, A. and others},
  title   = {{Galantamine-induced amyloid-beta clearance mediated via stimulation of microglial nicotinic acetylcholine receptors}},
  journal = {The Journal of biological chemistry},
  year    = {2010},
  doi     = {10.1074/jbc.m110.142356},
  pmid    = {20947502},
  url     = {https://doi.org/10.1074/jbc.m110.142356}
}

@article{liuyesucevitz2010-20948999,
  author  = {Liu-Yesucevitz, L. and Bilgutay, A. and Zhang, Y. J. and Vanderweyde, T. and Citro, A. and Mehta, T. and Zaarur, N. and McKee, A. and others},
  title   = {{Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue}},
  journal = {PloS one},
  year    = {2010},
  doi     = {10.1371/journal.pone.0013250},
  pmid    = {20948999},
  url     = {https://doi.org/10.1371/journal.pone.0013250}
}

@article{mackenzie2010-20864052,
  author  = {Mackenzie, I. R. and Rademakers, R. and Neumann, M.},
  title   = {{TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia}},
  journal = {The Lancet. Neurology},
  year    = {2010},
  doi     = {10.1016/s1474-4422(10)70195-2},
  pmid    = {20864052},
  url     = {https://doi.org/10.1016/s1474-4422(10)70195-2}
}

@article{tamboli2010-20876579,
  author  = {Tamboli, I. Y. and Barth, E. and Christian, L. and Siepmann, M. and Kumar, S. and Singh, S. and Tolksdorf, K. and Heneka, M. T. and others},
  title   = {{Statins promote the degradation of extracellular amyloid beta-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion}},
  journal = {The Journal of biological chemistry},
  year    = {2010},
  doi     = {10.1074/jbc.m110.149468},
  pmid    = {20876579},
  url     = {https://doi.org/10.1074/jbc.m110.149468}
}

@article{iranzo2010-20846908,
  author  = {Iranzo, A. and Lomeña, F. and Stockner, H. and Valldeoriola, F. and Vilaseca, I. and Salamero, M. and Molinuevo, J. L. and Serradell, M. and others},
  title   = {{Decreased striatal dopamine transporter uptake and substantia nigra hyperechogenicity as risk markers of synucleinopathy in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a prospective study [corrected]}},
  journal = {The Lancet. Neurology},
  year    = {2010},
  doi     = {10.1016/s1474-4422(10)70216-7},
  pmid    = {20846908},
  url     = {https://doi.org/10.1016/s1474-4422(10)70216-7}
}

@article{inoue2010-20832055,
  author  = {Inoue, H. and Yamasue, H. and Tochigi, M. and Abe, O. and Liu, X. and Kawamura, Y. and Takei, K. and Suga, M. and others},
  title   = {{Association between the oxytocin receptor gene and amygdalar volume in healthy adults}},
  journal = {Biological psychiatry},
  year    = {2010},
  doi     = {10.1016/j.biopsych.2010.07.019},
  pmid    = {20832055},
  url     = {https://doi.org/10.1016/j.biopsych.2010.07.019}
}

@article{mei2010-20813165,
  author  = {Mei, X. and Ezan, P. and Giaume, C. and Koulakoff, A.},
  title   = {{Astroglial connexin immunoreactivity is specifically altered at β-amyloid plaques in β-amyloid precursor protein/presenilin1 mice}},
  journal = {Neuroscience},
  year    = {2010},
  doi     = {10.1016/j.neuroscience.2010.08.001},
  pmid    = {20813165},
  url     = {https://doi.org/10.1016/j.neuroscience.2010.08.001}
}

@article{mckee2010-20720505,
  author  = {McKee, A. C. and Gavett, B. E. and Stern, R. A. and Nowinski, C. J. and Cantu, R. C. and Kowall, N. W. and Perl, D. P. and Hedley-Whyte, E. T. and others},
  title   = {{TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy}},
  journal = {Journal of neuropathology and experimental neurology},
  year    = {2010},
  doi     = {10.1097/nen.0b013e3181ee7d85},
  pmid    = {20720505},
  url     = {https://doi.org/10.1097/nen.0b013e3181ee7d85}
}

@article{donkin2010-20739291,
  author  = {Donkin, J. J. and Stukas, S. and Hirsch-Reinshagen, V. and Namjoshi, D. and Wilkinson, A. and May, S. and Chan, J. and Fan, J. and others},
  title   = {{ATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein/presenilin 1 mice}},
  journal = {The Journal of biological chemistry},
  year    = {2010},
  doi     = {10.1074/jbc.m110.108100},
  pmid    = {20739291},
  url     = {https://doi.org/10.1074/jbc.m110.108100}
}

@article{xu2010-20702714,
  author  = {Xu, Y. F. and Gendron, T. F. and Zhang, Y. J. and Lin, W. L. and D'Alton, S. and Sheng, H. and Casey, M. C. and Tong, J. and others},
  title   = {{Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2010},
  doi     = {10.1523/jneurosci.1630-10.2010},
  pmid    = {20702714},
  url     = {https://doi.org/10.1523/jneurosci.1630-10.2010}
}

@article{yin2010-20667979,
  author  = {Yin, F. and Dumont, M. and Banerjee, R. and Ma, Y. and Li, H. and Lin, M. T. and Beal, M. F. and Nathan, C. and others},
  title   = {{Behavioral deficits and progressive neuropathology in progranulin-deficient mice: a mouse model of frontotemporal dementia}},
  journal = {FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year    = {2010},
  doi     = {10.1096/fj.10-161471},
  pmid    = {20667979},
  url     = {https://doi.org/10.1096/fj.10-161471}
}

@article{park2010-20670674,
  author  = {Park, H. R. and Park, M. and Choi, J. and Park, K. Y. and Chung, H. Y. and Lee, J.},
  title   = {{A high-fat diet impairs neurogenesis: involvement of lipid peroxidation and brain-derived neurotrophic factor}},
  journal = {Neuroscience letters},
  year    = {2010},
  doi     = {10.1016/j.neulet.2010.07.046},
  pmid    = {20670674},
  url     = {https://doi.org/10.1016/j.neulet.2010.07.046}
}

@article{guglielmotto2012-20638753,
  author  = {Guglielmotto, M. and Aragno, M. and Tamagno, E. and Vercellinatto, I. and Visentin, S. and Medana, C. and Catalano, M. G. and Smith, M. A. and others},
  title   = {{AGEs/RAGE complex upregulates BACE1 via NF-κB pathway activation}},
  journal = {Neurobiology of aging},
  year    = {2012},
  doi     = {10.1016/j.neurobiolaging.2010.05.026},
  pmid    = {20638753},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2010.05.026}
}

@article{dormann2010-20606625,
  author  = {Dormann, D. and Rodde, R. and Edbauer, D. and Bentmann, E. and Fischer, I. and Hruscha, A. and Than, M. E. and Mackenzie, I. R. and others},
  title   = {{ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import}},
  journal = {The EMBO journal},
  year    = {2010},
  doi     = {10.1038/emboj.2010.143},
  pmid    = {20606625},
  url     = {https://doi.org/10.1038/emboj.2010.143}
}

@article{lee2010-20972375,
  author  = {Lee, H. J. and Kim, C. and Lee, S. J.},
  title   = {{Alpha-synuclein stimulation of astrocytes: Potential role for neuroinflammation and neuroprotection}},
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  year    = {2010},
  doi     = {10.4161/oxim.3.4.12809},
  pmid    = {20972375},
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}

@article{liang2010-20595388,
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  title   = {{Calpain activation promotes BACE1 expression, amyloid precursor protein processing, and amyloid plaque formation in a transgenic mouse model of Alzheimer disease}},
  journal = {The Journal of biological chemistry},
  year    = {2010},
  doi     = {10.1074/jbc.m110.117960},
  pmid    = {20595388},
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}

@article{linnartz2010-20721346,
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  title   = {{Microglial immunoreceptor tyrosine-based activation and inhibition motif signaling in neuroinflammation}},
  journal = {International journal of Alzheimer's disease},
  year    = {2010},
  doi     = {10.4061/2010/587463},
  pmid    = {20721346},
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}

@article{ash2010-20530643,
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  title   = {{Neurotoxic effects of TDP-43 overexpression in C. elegans}},
  journal = {Human molecular genetics},
  year    = {2010},
  doi     = {10.1093/hmg/ddq230},
  pmid    = {20530643},
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}

@article{lu2010-20460993,
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  title   = {{Anesthetic sevoflurane causes neurotoxicity differently in neonatal naïve and Alzheimer disease transgenic mice}},
  journal = {Anesthesiology},
  year    = {2010},
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  pmid    = {20460993},
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@article{ritson2010-20519548,
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  title   = {{TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2010},
  doi     = {10.1523/jneurosci.5894-09.2010},
  pmid    = {20519548},
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@article{yokota2010-20512649,
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  title   = {{Phosphorylated TDP-43 pathology and hippocampal sclerosis in progressive supranuclear palsy}},
  journal = {Acta neuropathologica},
  year    = {2010},
  doi     = {10.1007/s00401-010-0702-1},
  pmid    = {20512649},
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@article{rodrigueznavarro2010-20546895,
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  title   = {{Trehalose ameliorates dopaminergic and tau pathology in parkin deleted/tau overexpressing mice through autophagy activation}},
  journal = {Neurobiology of disease},
  year    = {2010},
  doi     = {10.1016/j.nbd.2010.05.014},
  pmid    = {20546895},
  url     = {https://doi.org/10.1016/j.nbd.2010.05.014}
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@article{zong2010-20504772,
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  title   = {{Homodimerization is essential for the receptor for advanced glycation end products (RAGE)-mediated signal transduction}},
  journal = {The Journal of biological chemistry},
  year    = {2010},
  doi     = {10.1074/jbc.m110.133827},
  pmid    = {20504772},
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@article{kang2010-20484053,
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  title   = {{Ubiquitin regulates GGA3-mediated degradation of BACE1}},
  journal = {The Journal of biological chemistry},
  year    = {2010},
  doi     = {10.1074/jbc.m109.092742},
  pmid    = {20484053},
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@article{shinohara2010-20472556,
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  title   = {{Reduction of brain beta-amyloid (Abeta) by fluvastatin, a hydroxymethylglutaryl-CoA reductase inhibitor, through increase in degradation of amyloid precursor protein C-terminal fragments (APP-CTFs) and Abeta clearance}},
  journal = {The Journal of biological chemistry},
  year    = {2010},
  doi     = {10.1074/jbc.m110.102277},
  pmid    = {20472556},
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@article{persengiev2011-20451302,
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  title   = {{Genome-wide analysis of miRNA expression reveals a potential role for miR-144 in brain aging and spinocerebellar ataxia pathogenesis}},
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@article{mcallister2010-20505099,
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  title   = {{Genetic targeting aromatase in male amyloid precursor protein transgenic mice down-regulates beta-secretase (BACE1) and prevents Alzheimer-like pathology and cognitive impairment}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2010},
  doi     = {10.1523/jneurosci.1180-10.2010},
  pmid    = {20505099},
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@article{gu2010-20409326,
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  title   = {{Astrocytic expression of Parkinson's disease-related A53T alpha-synuclein causes neurodegeneration in mice}},
  journal = {Molecular brain},
  year    = {2010},
  doi     = {10.1186/1756-6606-3-12},
  pmid    = {20409326},
  url     = {https://doi.org/10.1186/1756-6606-3-12}
}

@article{vilardo2010-20395292,
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  title   = {{MicroRNA-101 regulates amyloid precursor protein expression in hippocampal neurons}},
  journal = {The Journal of biological chemistry},
  year    = {2010},
  doi     = {10.1074/jbc.m110.112664},
  pmid    = {20395292},
  url     = {https://doi.org/10.1074/jbc.m110.112664}
}

@article{lagiertourenne2010-20400460,
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  title   = {{TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration}},
  journal = {Human molecular genetics},
  year    = {2010},
  doi     = {10.1093/hmg/ddq137},
  pmid    = {20400460},
  url     = {https://doi.org/10.1093/hmg/ddq137}
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@article{decalignon2010-20357768,
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  title   = {{Caspase activation precedes and leads to tangles}},
  journal = {Nature},
  year    = {2010},
  doi     = {10.1038/nature08890},
  pmid    = {20357768},
  url     = {https://doi.org/10.1038/nature08890}
}

@article{butterworth2010-20350577,
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  title   = {{Altered glial-neuronal crosstalk: cornerstone in the pathogenesis of hepatic encephalopathy}},
  journal = {Neurochemistry international},
  year    = {2010},
  doi     = {10.1016/j.neuint.2010.03.012},
  pmid    = {20350577},
  url     = {https://doi.org/10.1016/j.neuint.2010.03.012}
}

@article{chenplotkin2010-20234357,
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  title   = {{TAR DNA-binding protein 43 in neurodegenerative disease}},
  journal = {Nature reviews. Neurology},
  year    = {2010},
  doi     = {10.1038/nrneurol.2010.18},
  pmid    = {20234357},
  url     = {https://doi.org/10.1038/nrneurol.2010.18}
}

@article{lee2010-20228251,
  author  = {Lee, M. and Cho, T. and Jantaratnotai, N. and Wang, Y. T. and McGeer, E. and McGeer, P. L.},
  title   = {{Depletion of GSH in glial cells induces neurotoxicity: relevance to aging and degenerative neurological diseases}},
  journal = {FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year    = {2010},
  doi     = {10.1096/fj.09-149997},
  pmid    = {20228251},
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@article{brandt2010-20224659,
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  title   = {{The role of exercise-induced myokines in muscle homeostasis and the defense against chronic diseases}},
  journal = {Journal of biomedicine \& biotechnology},
  year    = {2010},
  doi     = {10.1155/2010/520258},
  pmid    = {20224659},
  url     = {https://doi.org/10.1155/2010/520258}
}

@article{tresse2010-20104022,
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  title   = {{VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD}},
  journal = {Autophagy},
  year    = {2010},
  doi     = {10.4161/auto.6.2.11014},
  pmid    = {20104022},
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@article{crews2010-20174468,
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  title   = {{Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alpha-synucleinopathy}},
  journal = {PloS one},
  year    = {2010},
  doi     = {10.1371/journal.pone.0009313},
  pmid    = {20174468},
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@article{venkataramani2010-20145244,
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  title   = {{Histone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the alzheimer amyloid precursor protein}},
  journal = {The Journal of biological chemistry},
  year    = {2010},
  doi     = {10.1074/jbc.m109.057836},
  pmid    = {20145244},
  url     = {https://doi.org/10.1074/jbc.m109.057836}
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@article{wils2010-20133711,
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  title   = {{TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2010},
  doi     = {10.1073/pnas.0912417107},
  pmid    = {20133711},
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@article{freibaum2010-20020773,
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  title   = {{Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery}},
  journal = {Journal of proteome research},
  year    = {2010},
  doi     = {10.1021/pr901076y},
  pmid    = {20020773},
  url     = {https://doi.org/10.1021/pr901076y}
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@article{mori2010-19705461,
  author  = {Mori, T. and Koyama, N. and Arendash, G. W. and Horikoshi-Sakuraba, Y. and Tan, J. and Town, T.},
  title   = {{Overexpression of human S100B exacerbates cerebral amyloidosis and gliosis in the Tg2576 mouse model of Alzheimer's disease}},
  journal = {Glia},
  year    = {2010},
  doi     = {10.1002/glia.20924},
  pmid    = {19705461},
  url     = {https://doi.org/10.1002/glia.20924}
}

@article{li2010-20133767,
  author  = {Li, Y. and Ray, P. and Rao, E. J. and Shi, C. and Guo, W. and Chen, X. and Woodruff, E. A. and Fushimi, K. and others},
  title   = {{A Drosophila model for TDP-43 proteinopathy}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2010},
  doi     = {10.1073/pnas.0913602107},
  pmid    = {20133767},
  url     = {https://doi.org/10.1073/pnas.0913602107}
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@article{barmada2010-20071528,
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  title   = {{Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2010},
  doi     = {10.1523/jneurosci.4988-09.2010},
  pmid    = {20071528},
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@article{plaschke2010-20110613,
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  title   = {{Insulin-resistant brain state after intracerebroventricular streptozotocin injection exacerbates Alzheimer-like changes in Tg2576 AbetaPP-overexpressing mice}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2010},
  doi     = {10.3233/jad-2010-1270},
  pmid    = {20110613},
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@article{sephton2010-20040602,
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  title   = {{TDP-43 is a developmentally regulated protein essential for early embryonic development}},
  journal = {The Journal of biological chemistry},
  year    = {2010},
  doi     = {10.1074/jbc.m109.061846},
  pmid    = {20040602},
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@article{zhao2010-20032460,
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  title   = {{Inhibition of calcineurin-mediated endocytosis and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors prevents amyloid beta oligomer-induced synaptic disruption}},
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  year    = {2010},
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  pmid    = {20032460},
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@article{yin2010-20026663,
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  title   = {{Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice}},
  journal = {The Journal of experimental medicine},
  year    = {2010},
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  pmid    = {20026663},
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@article{kabashi2010-19959528,
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  title   = {{Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo}},
  journal = {Human molecular genetics},
  year    = {2010},
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  pmid    = {19959528},
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@article{ju2009-20008565,
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  title   = {{Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease}},
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  year    = {2009},
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  pmid    = {20008565},
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@article{fiesel2010-19910924,
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  title   = {{Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6}},
  journal = {The EMBO journal},
  year    = {2010},
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  pmid    = {19910924},
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@article{varvel2009-19907078,
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  title   = {{NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease}},
  journal = {The Journal of clinical investigation},
  year    = {2009},
  doi     = {10.1172/jci39716},
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@article{luk2009-19892735,
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  title   = {{Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells}},
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  year    = {2009},
  doi     = {10.1073/pnas.0908005106},
  pmid    = {19892735},
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@article{choi2009-19837759,
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  title   = {{Preclinical properties of 18F-AV-45: a PET agent for Abeta plaques in the brain}},
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  year    = {2009},
  doi     = {10.2967/jnumed.109.065284},
  pmid    = {19837759},
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@article{wegorzewska2009-19833869,
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  title   = {{TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2009},
  doi     = {10.1073/pnas.0908767106},
  pmid    = {19833869},
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@article{whiteman2009-19828813,
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  title   = {{Activated actin-depolymerizing factor/cofilin sequesters phosphorylated microtubule-associated protein during the assembly of alzheimer-like neuritic cytoskeletal striations}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2009},
  doi     = {10.1523/jneurosci.3531-09.2009},
  pmid    = {19828813},
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@article{spencer2009-19864570,
  author  = {Spencer, B. and Potkar, R. and Trejo, M. and Rockenstein, E. and Patrick, C. and Gindi, R. and Adame, A. and Wyss-Coray, T. and others},
  title   = {{Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2009},
  doi     = {10.1523/jneurosci.4390-09.2009},
  pmid    = {19864570},
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@article{colombrita2009-19765185,
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  title   = {{TDP-43 is recruited to stress granules in conditions of oxidative insult}},
  journal = {Journal of neurochemistry},
  year    = {2009},
  doi     = {10.1111/j.1471-4159.2009.06383.x},
  pmid    = {19765185},
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@article{durakoglugil2009-19805234,
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  title   = {{Reelin signaling antagonizes beta-amyloid at the synapse}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2009},
  doi     = {10.1073/pnas.0908176106},
  pmid    = {19805234},
  url     = {https://doi.org/10.1073/pnas.0908176106}
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@article{mouton2009-19699265,
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  title   = {{Caloric restriction attenuates amyloid deposition in middle-aged dtg APP/PS1 mice}},
  journal = {Neuroscience letters},
  year    = {2009},
  doi     = {10.1016/j.neulet.2009.08.038},
  pmid    = {19699265},
  url     = {https://doi.org/10.1016/j.neulet.2009.08.038}
}

@article{desplats2009-19651612,
  author  = {Desplats, P. and Lee, H. J. and Bae, E. J. and Patrick, C. and Rockenstein, E. and Crews, L. and Spencer, B. and Masliah, E. and others},
  title   = {{Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein}},
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  year    = {2009},
  doi     = {10.1073/pnas.0903691106},
  pmid    = {19651612},
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@article{blurtonjones2009-19633196,
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  title   = {{Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2009},
  doi     = {10.1073/pnas.0901402106},
  pmid    = {19633196},
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@article{lee2009-19631409,
  author  = {Lee, M. and Schwab, C. and Yu, S. and McGeer, E. and McGeer, P. L.},
  title   = {{Astrocytes produce the antiinflammatory and neuroprotective agent hydrogen sulfide}},
  journal = {Neurobiology of aging},
  year    = {2009},
  doi     = {10.1016/j.neurobiolaging.2009.06.001},
  pmid    = {19631409},
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}

@article{johnson2009-19465477,
  author  = {Johnson, B. S. and Snead, D. and Lee, J. J. and McCaffery, J. M. and Shorter, J. and Gitler, A. D.},
  title   = {{TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity}},
  journal = {The Journal of biological chemistry},
  year    = {2009},
  doi     = {10.1074/jbc.m109.010264},
  pmid    = {19465477},
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}

@article{sugata2009-19414059,
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  title   = {{A peptidyl-prolyl isomerase, FKBP12, accumulates in Alzheimer neurofibrillary tangles}},
  journal = {Neuroscience letters},
  year    = {2009},
  doi     = {10.1016/j.neulet.2009.04.062},
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@article{li2009-19380826,
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  title   = {{Amyloid beta interaction with receptor for advanced glycation end products up-regulates brain endothelial CCR5 expression and promotes T cells crossing the blood-brain barrier}},
  journal = {Journal of immunology (Baltimore, Md. : 1950)},
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@article{schmid2009-19393017,
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  title   = {{Differential gene expression in LPS/IFNgamma activated microglia and macrophages: in vitro versus in vivo}},
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  year    = {2009},
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@article{dong2009-19433662,
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  title   = {{The common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels}},
  journal = {Archives of neurology},
  year    = {2009},
  doi     = {10.1001/archneurol.2009.48},
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@article{zhao2009-19406747,
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  title   = {{Insulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric abeta}},
  journal = {The Journal of biological chemistry},
  year    = {2009},
  doi     = {10.1074/jbc.m109.011015},
  pmid    = {19406747},
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@article{lee2009-19394434,
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  title   = {{CCR5 deficiency induces astrocyte activation, Abeta deposit and impaired memory function}},
  journal = {Neurobiology of learning and memory},
  year    = {2009},
  doi     = {10.1016/j.nlm.2009.04.003},
  pmid    = {19394434},
  url     = {https://doi.org/10.1016/j.nlm.2009.04.003}
}

@article{zhang2009-19383787,
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  title   = {{Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2009},
  doi     = {10.1073/pnas.0900688106},
  pmid    = {19383787},
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@article{du2011-19362755,
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  title   = {{Cyclophilin D deficiency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model}},
  journal = {Neurobiology of aging},
  year    = {2011},
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  pmid    = {19362755},
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}

@article{sanz2009-19299738,
  author  = {Sanz, J. M. and Chiozzi, P. and Ferrari, D. and Colaianna, M. and Idzko, M. and Falzoni, S. and Fellin, R. and Trabace, L. and others},
  title   = {{Activation of microglia by amyloid beta requires P2X7 receptor expression}},
  journal = {Journal of immunology (Baltimore, Md. : 1950)},
  year    = {2009},
  doi     = {10.4049/jimmunol.0803612},
  pmid    = {19299738},
  url     = {https://doi.org/10.4049/jimmunol.0803612}
}

@article{yu2009-19339601,
  author  = {Yu, H. and Wang, Y. and Pattwell, S. and Jing, D. and Liu, T. and Zhang, Y. and Bath, K. G. and Lee, F. S. and others},
  title   = {{Variant BDNF Val66Met polymorphism affects extinction of conditioned aversive memory}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2009},
  doi     = {10.1523/jneurosci.5539-08.2009},
  pmid    = {19339601},
  url     = {https://doi.org/10.1523/jneurosci.5539-08.2009}
}

@article{zensi2009-19285109,
  author  = {Zensi, A. and Begley, D. and Pontikis, C. and Legros, C. and Mihoreanu, L. and Wagner, S. and Büchel, C. and von Briesen, H. and others},
  title   = {{Albumin nanoparticles targeted with Apo E enter the CNS by transcytosis and are delivered to neurones}},
  journal = {Journal of controlled release : official journal of the Controlled Release Society},
  year    = {2009},
  doi     = {10.1016/j.jconrel.2009.03.002},
  pmid    = {19285109},
  url     = {https://doi.org/10.1016/j.jconrel.2009.03.002}
}

@article{zhang2009-19264913,
  author  = {Zhang, C. E. and Wei, W. and Liu, Y. H. and Peng, J. H. and Tian, Q. and Liu, G. P. and Zhang, Y. and Wang, J. Z.},
  title   = {{Hyperhomocysteinemia increases beta-amyloid by enhancing expression of gamma-secretase and phosphorylation of amyloid precursor protein in rat brain}},
  journal = {The American journal of pathology},
  year    = {2009},
  doi     = {10.2353/ajpath.2009.081036},
  pmid    = {19264913},
  url     = {https://doi.org/10.2353/ajpath.2009.081036}
}

@article{terni2010-19298596,
  author  = {Terni, B. and Boada, J. and Portero-Otin, M. and Pamplona, R. and Ferrer, I.},
  title   = {{Mitochondrial ATP-synthase in the entorhinal cortex is a target of oxidative stress at stages I/II of Alzheimer's disease pathology}},
  journal = {Brain pathology (Zurich, Switzerland)},
  year    = {2010},
  doi     = {10.1111/j.1750-3639.2009.00266.x},
  pmid    = {19298596},
  url     = {https://doi.org/10.1111/j.1750-3639.2009.00266.x}
}

@article{vance2009-19251628,
  author  = {Vance, Caroline A. and Rogelj, Boris and Hortobágyi, Tibor and De Vos, Kurt J. and Nishimura, Agnes Lumi and Sreedharan, Jemeen and Hu, Xun and Smith, Bradley N. and Ruddy, Deborah and Wright, Paul D. and Ganesalingam, Jeban and Williams, Kelly L. and Tripathi, Vineeta and Al‐Saraj, Safa and Al‐Chalabi, Ammar and Leigh, P. Nigel and Blair, Ian P. and Nicholson, Garth A. and de Belleroche, Jackie and Gallo, Jean‐Marc and Miller, Christopher C.J. and Shaw, Christopher E.},
  title   = {{Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6}},
  journal = {Science},
  year    = {2009},
  doi     = {10.1126/science.1165942},
  pmid    = {19251628},
  url     = {https://doi.org/10.1126/science.1165942}
}

@article{gu2009-19240035,
  author  = {Gu, Z. and Liu, W. and Yan, Z.},
  title   = {{beta-Amyloid impairs AMPA receptor trafficking and function by reducing Ca2+/calmodulin-dependent protein kinase II synaptic distribution}},
  journal = {The Journal of biological chemistry},
  year    = {2009},
  doi     = {10.1074/jbc.m806508200},
  pmid    = {19240035},
  url     = {https://doi.org/10.1074/jbc.m806508200}
}

@article{gitler2009-19182805,
  author  = {Gitler, A. D. and Chesi, A. and Geddie, M. L. and Strathearn, K. E. and Hamamichi, S. and Hill, K. J. and Caldwell, K. A. and Caldwell, G. A. and others},
  title   = {{Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity}},
  journal = {Nature genetics},
  year    = {2009},
  doi     = {10.1038/ng.300},
  pmid    = {19182805},
  url     = {https://doi.org/10.1038/ng.300}
}

@article{kuchibhotla2009-19251629,
  author  = {Kuchibhotla, K. V. and Lattarulo, C. R. and Hyman, B. T. and Bacskai, B. J.},
  title   = {{Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice}},
  journal = {Science (New York, N.Y.)},
  year    = {2009},
  doi     = {10.1126/science.1169096},
  pmid    = {19251629},
  url     = {https://doi.org/10.1126/science.1169096}
}

@article{igaz2009-19164285,
  author  = {Igaz, L. M. and Kwong, L. K. and Chen-Plotkin, A. and Winton, M. J. and Unger, T. L. and Xu, Y. and Neumann, M. and Trojanowski, J. Q. and others},
  title   = {{Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies}},
  journal = {The Journal of biological chemistry},
  year    = {2009},
  doi     = {10.1074/jbc.m809462200},
  pmid    = {19164285},
  url     = {https://doi.org/10.1074/jbc.m809462200}
}

@article{lourenco2009-19148186,
  author  = {Lourenço, F. C. and Galvan, V. and Fombonne, J. and Corset, V. and Llambi, F. and Müller, U. and Bredesen, D. E. and Mehlen, P.},
  title   = {{Netrin-1 interacts with amyloid precursor protein and regulates amyloid-beta production}},
  journal = {Cell death and differentiation},
  year    = {2009},
  doi     = {10.1038/cdd.2008.191},
  pmid    = {19148186},
  url     = {https://doi.org/10.1038/cdd.2008.191}
}

@article{tchantchou2009-19661619,
  author  = {Tchantchou, F. and Lacor, P. N. and Cao, Z. and Lao, L. and Hou, Y. and Cui, C. and Klein, W. L. and Luo, Y.},
  title   = {{Stimulation of neurogenesis and synaptogenesis by bilobalide and quercetin via common final pathway in hippocampal neurons}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2009},
  doi     = {10.3233/jad-2009-1189},
  pmid    = {19661619},
  url     = {https://doi.org/10.3233/jad-2009-1189}
}

@article{schwab2008-19018245,
  author  = {Schwab, C. and Arai, T. and Hasegawa, M. and Yu, S. and McGeer, P. L.},
  title   = {{Colocalization of transactivation-responsive DNA-binding protein 43 and huntingtin in inclusions of Huntington disease}},
  journal = {Journal of neuropathology and experimental neurology},
  year    = {2008},
  doi     = {10.1097/nen.0b013e31818e8951},
  pmid    = {19018245},
  url     = {https://doi.org/10.1097/nen.0b013e31818e8951}
}

@article{ko2009-19011241,
  author  = {Ko, M. H. and Puglielli, L.},
  title   = {{Two endoplasmic reticulum (ER)/ER Golgi intermediate compartment-based lysine acetyltransferases post-translationally regulate BACE1 levels}},
  journal = {The Journal of biological chemistry},
  year    = {2009},
  doi     = {10.1074/jbc.m804901200},
  pmid    = {19011241},
  url     = {https://doi.org/10.1074/jbc.m804901200}
}

@article{ayala2008-18957508,
  author  = {Ayala, Y. M. and Zago, P. and D'Ambrogio, A. and Xu, Y. F. and Petrucelli, L. and Buratti, E. and Baralle, F. E.},
  title   = {{Structural determinants of the cellular localization and shuttling of TDP-43}},
  journal = {Journal of cell science},
  year    = {2008},
  doi     = {10.1242/jcs.038950},
  pmid    = {18957508},
  url     = {https://doi.org/10.1242/jcs.038950}
}

@article{zhang2008-18952609,
  author  = {Zhang, L. and Bukulin, M. and Kojro, E. and Roth, A. and Metz, V. V. and Fahrenholz, F. and Nawroth, P. P. and Bierhaus, A. and others},
  title   = {{Receptor for advanced glycation end products is subjected to protein ectodomain shedding by metalloproteinases}},
  journal = {The Journal of biological chemistry},
  year    = {2008},
  doi     = {10.1074/jbc.m806948200},
  pmid    = {18952609},
  url     = {https://doi.org/10.1074/jbc.m806948200}
}

@article{weihl2008-18796596,
  author  = {Weihl, C. C. and Temiz, P. and Miller, S. E. and Watts, G. and Smith, C. and Forman, M. and Hanson, P. I. and Kimonis, V. and others},
  title   = {{TDP-43 accumulation in inclusion body myopathy muscle suggests a common pathogenic mechanism with frontotemporal dementia}},
  journal = {Journal of neurology, neurosurgery, and psychiatry},
  year    = {2008},
  doi     = {10.1136/jnnp.2007.131334},
  pmid    = {18796596},
  url     = {https://doi.org/10.1136/jnnp.2007.131334}
}

@article{schilling2008-18836460,
  author  = {Schilling, S. and Zeitschel, U. and Hoffmann, T. and Heiser, U. and Francke, M. and Kehlen, A. and Holzer, M. and Hutter-Paier, B. and others},
  title   = {{Glutaminyl cyclase inhibition attenuates pyroglutamate Abeta and Alzheimer's disease-like pathology}},
  journal = {Nature medicine},
  year    = {2008},
  doi     = {10.1038/nm.1872},
  pmid    = {18836460},
  url     = {https://doi.org/10.1038/nm.1872}
}

@article{matos2008-18790019,
  author  = {Matos, M. and Augusto, E. and Oliveira, C. R. and Agostinho, P.},
  title   = {{Amyloid-beta peptide decreases glutamate uptake in cultured astrocytes: involvement of oxidative stress and mitogen-activated protein kinase cascades}},
  journal = {Neuroscience},
  year    = {2008},
  doi     = {10.1016/j.neuroscience.2008.08.022},
  pmid    = {18790019},
  url     = {https://doi.org/10.1016/j.neuroscience.2008.08.022}
}

@article{rademakers2008-18723524,
  author  = {Rademakers, R. and Eriksen, J. L. and Baker, M. and Robinson, T. and Ahmed, Z. and Lincoln, S. J. and Finch, N. and Rutherford, N. J. and others},
  title   = {{Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia}},
  journal = {Human molecular genetics},
  year    = {2008},
  doi     = {10.1093/hmg/ddn257},
  pmid    = {18723524},
  url     = {https://doi.org/10.1093/hmg/ddn257}
}

@article{jonas2008-18660751,
  author  = {Jonas, M. C. and Costantini, C. and Puglielli, L.},
  title   = {{PCSK9 is required for the disposal of non-acetylated intermediates of the nascent membrane protein BACE1}},
  journal = {EMBO reports},
  year    = {2008},
  doi     = {10.1038/embor.2008.132},
  pmid    = {18660751},
  url     = {https://doi.org/10.1038/embor.2008.132}
}

@article{roumier2008-18612411,
  author  = {Roumier, A. and Pascual, O. and Béchade, C. and Wakselman, S. and Poncer, J. C. and Réal, E. and Triller, A. and Bessis, A.},
  title   = {{Prenatal activation of microglia induces delayed impairment of glutamatergic synaptic function}},
  journal = {PloS one},
  year    = {2008},
  doi     = {10.1371/journal.pone.0002595},
  pmid    = {18612411},
  url     = {https://doi.org/10.1371/journal.pone.0002595}
}

@article{marcade2008-18397369,
  author  = {Marcade, M. and Bourdin, J. and Loiseau, N. and Peillon, H. and Rayer, A. and Drouin, D. and Schweighoffer, F. and Désiré, L.},
  title   = {{Etazolate, a neuroprotective drug linking GABA(A) receptor pharmacology to amyloid precursor protein processing}},
  journal = {Journal of neurochemistry},
  year    = {2008},
  doi     = {10.1111/j.1471-4159.2008.05396.x},
  pmid    = {18397369},
  url     = {https://doi.org/10.1111/j.1471-4159.2008.05396.x}
}

@article{thirumangalakudi2008-18410513,
  author  = {Thirumangalakudi, L. and Prakasam, A. and Zhang, R. and Bimonte-Nelson, H. and Sambamurti, K. and Kindy, M. S. and Bhat, N. R.},
  title   = {{High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice}},
  journal = {Journal of neurochemistry},
  year    = {2008},
  doi     = {10.1111/j.1471-4159.2008.05415.x},
  pmid    = {18410513},
  url     = {https://doi.org/10.1111/j.1471-4159.2008.05415.x}
}

@article{hasegawa2008-18546284,
  author  = {Hasegawa, M. and Arai, T. and Nonaka, T. and Kametani, F. and Yoshida, M. and Hashizume, Y. and Beach, T. G. and Buratti, E. and others},
  title   = {{Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis}},
  journal = {Annals of neurology},
  year    = {2008},
  doi     = {10.1002/ana.21425},
  pmid    = {18546284},
  url     = {https://doi.org/10.1002/ana.21425}
}

@article{hwang2008-18639562,
  author  = {Hwang, J. and Zheng, L. T. and Ock, J. and Lee, M. G. and Kim, S. H. and Lee, H. W. and Lee, W. H. and Park, H. C. and others},
  title   = {{Inhibition of glial inflammatory activation and neurotoxicity by tricyclic antidepressants}},
  journal = {Neuropharmacology},
  year    = {2008},
  doi     = {10.1016/j.neuropharm.2008.06.045},
  pmid    = {18639562},
  url     = {https://doi.org/10.1016/j.neuropharm.2008.06.045}
}

@article{ancuta2008-18575590,
  author  = {Ancuta, P. and Kamat, A. and Kunstman, K. J. and Kim, E. Y. and Autissier, P. and Wurcel, A. and Zaman, T. and Stone, D. and others},
  title   = {{Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients}},
  journal = {PloS one},
  year    = {2008},
  doi     = {10.1371/journal.pone.0002516},
  pmid    = {18575590},
  url     = {https://doi.org/10.1371/journal.pone.0002516}
}

@article{igaz2008-18535185,
  author  = {Igaz, L. M. and Kwong, L. K. and Xu, Y. and Truax, A. C. and Uryu, K. and Neumann, M. and Clark, C. M. and Elman, L. B. and others},
  title   = {{Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis}},
  journal = {The American journal of pathology},
  year    = {2008},
  doi     = {10.2353/ajpath.2008.080003},
  pmid    = {18535185},
  url     = {https://doi.org/10.2353/ajpath.2008.080003}
}

@article{vedin2008-18541548,
  author  = {Vedin, I. and Cederholm, T. and Freund Levi, Y. and Basun, H. and Garlind, A. and Faxén Irving, G. and Jönhagen, M. E. and Vessby, B. and others},
  title   = {{Effects of docosahexaenoic acid-rich n-3 fatty acid supplementation on cytokine release from blood mononuclear leukocytes: the OmegAD study}},
  journal = {The American journal of clinical nutrition},
  year    = {2008},
  doi     = {10.1093/ajcn/87.6.1616},
  pmid    = {18541548},
  url     = {https://doi.org/10.1093/ajcn/87.6.1616}
}

@article{lee2008-18492487,
  author  = {Lee, H. J. and Suk, J. E. and Bae, E. J. and Lee, S. J.},
  title   = {{Clearance and deposition of extracellular alpha-synuclein aggregates in microglia}},
  journal = {Biochemical and biophysical research communications},
  year    = {2008},
  doi     = {10.1016/j.bbrc.2008.05.045},
  pmid    = {18492487},
  url     = {https://doi.org/10.1016/j.bbrc.2008.05.045}
}

@article{gu2008-18539391,
  author  = {Gu, F. and Zhu, M. and Shi, J. and Hu, Y. and Zhao, Z.},
  title   = {{Enhanced oxidative stress is an early event during development of Alzheimer-like pathologies in presenilin conditional knock-out mice}},
  journal = {Neuroscience letters},
  year    = {2008},
  doi     = {10.1016/j.neulet.2008.05.050},
  pmid    = {18539391},
  url     = {https://doi.org/10.1016/j.neulet.2008.05.050}
}

@article{jin2008-18483410,
  author  = {Jin, S. and Hansson, E. M. and Tikka, S. and Lanner, F. and Sahlgren, C. and Farnebo, F. and Baumann, M. and Kalimo, H. and others},
  title   = {{Notch signaling regulates platelet-derived growth factor receptor-beta expression in vascular smooth muscle cells}},
  journal = {Circulation research},
  year    = {2008},
  doi     = {10.1161/circresaha.107.167965},
  pmid    = {18483410},
  url     = {https://doi.org/10.1161/circresaha.107.167965}
}

@article{shen2008-18436531,
  author  = {Shen, C. and Chen, Y. and Liu, H. and Zhang, K. and Zhang, T. and Lin, A. and Jing, N.},
  title   = {{Hydrogen peroxide promotes Abeta production through JNK-dependent activation of gamma-secretase}},
  journal = {The Journal of biological chemistry},
  year    = {2008},
  doi     = {10.1074/jbc.m800013200},
  pmid    = {18436531},
  url     = {https://doi.org/10.1074/jbc.m800013200}
}

@article{josephs2008-18401022,
  author  = {Josephs, K. A. and Whitwell, J. L. and Knopman, D. S. and Hu, W. T. and Stroh, D. A. and Baker, M. and Rademakers, R. and Boeve, B. F. and others},
  title   = {{Abnormal TDP-43 immunoreactivity in AD modifies clinicopathologic and radiologic phenotype}},
  journal = {Neurology},
  year    = {2008},
  doi     = {10.1212/01.wnl.0000304041.09418.b1},
  pmid    = {18401022},
  url     = {https://doi.org/10.1212/01.wnl.0000304041.09418.b1}
}

@article{rezaizadeh2008-18457818,
  author  = {Rezai-Zadeh, K. and Arendash, G. W. and Hou, H. and Fernandez, F. and Jensen, M. and Runfeldt, M. and Shytle, R. D. and Tan, J.},
  title   = {{Green tea epigallocatechin-3-gallate (EGCG) reduces beta-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice}},
  journal = {Brain research},
  year    = {2008},
  doi     = {10.1016/j.brainres.2008.02.107},
  pmid    = {18457818},
  url     = {https://doi.org/10.1016/j.brainres.2008.02.107}
}

@article{vandamme2008-18378771,
  author  = {Van Damme, P. and Van Hoecke, A. and Lambrechts, D. and Vanacker, P. and Bogaert, E. and van Swieten, J. and Carmeliet, P. and Van Den Bosch, L. and others},
  title   = {{Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival}},
  journal = {The Journal of cell biology},
  year    = {2008},
  doi     = {10.1083/jcb.200712039},
  pmid    = {18378771},
  url     = {https://doi.org/10.1083/jcb.200712039}
}

@article{lee2008-18326497,
  author  = {Lee, S. G. and Su, Z. Z. and Emdad, L. and Gupta, P. and Sarkar, D. and Borjabad, A. and Volsky, D. J. and Fisher, P. B.},
  title   = {{Mechanism of ceftriaxone induction of excitatory amino acid transporter-2 expression and glutamate uptake in primary human astrocytes}},
  journal = {The Journal of biological chemistry},
  year    = {2008},
  doi     = {10.1074/jbc.m707697200},
  pmid    = {18326497},
  url     = {https://doi.org/10.1074/jbc.m707697200}
}

@article{sreedharan2008-18309045,
  author  = {Sreedharan, Jemeen and Blair, Ian P. and Tripathi, Vineeta B. and Hu, Xun and Vance, Caroline A. and Rogelj, Boris and Ackerley, Steven and Durnall, Jennifer C. and others},
  title   = {{TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis}},
  journal = {Science},
  year    = {2008},
  doi     = {10.1126/science.1154584},
  pmid    = {18309045},
  url     = {https://doi.org/10.1126/science.1154584}
}

@article{winton2008-18305110,
  author  = {Winton, M. J. and Igaz, L. M. and Wong, M. M. and Kwong, L. K. and Trojanowski, J. Q. and Lee, V. M.},
  title   = {{Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation}},
  journal = {The Journal of biological chemistry},
  year    = {2008},
  doi     = {10.1074/jbc.m800342200},
  pmid    = {18305110},
  url     = {https://doi.org/10.1074/jbc.m800342200}
}

@article{gratchev2008-19578492,
  author  = {Gratchev, A. and Schmuttermaier, C. and Mamidi, S. and Gooi, L. and Goerdt, S. and Kzhyshkowska, J.},
  title   = {{Expression of Osteoarthritis Marker YKL-39 is Stimulated by Transforming Growth Factor Beta (TGF-beta) and IL-4 in Differentiating Macrophages}},
  journal = {Biomarker insights},
  year    = {2008},
  pmid    = {19578492}
}

@article{lee2008-18276590,
  author  = {Lee, J. and Retamal, C. and Cuitiño, L. and Caruano-Yzermans, A. and Shin, J. E. and van Kerkhof, P. and Marzolo, M. P. and Bu, G.},
  title   = {{Adaptor protein sorting nexin 17 regulates amyloid precursor protein trafficking and processing in the early endosomes}},
  journal = {The Journal of biological chemistry},
  year    = {2008},
  doi     = {10.1074/jbc.m800642200},
  pmid    = {18276590},
  url     = {https://doi.org/10.1074/jbc.m800642200}
}

@article{buggiaprevot2008-18263584,
  author  = {Buggia-Prevot, V. and Sevalle, J. and Rossner, S. and Checler, F.},
  title   = {{NFkappaB-dependent control of BACE1 promoter transactivation by Abeta42}},
  journal = {The Journal of biological chemistry},
  year    = {2008},
  doi     = {10.1074/jbc.m706579200},
  pmid    = {18263584},
  url     = {https://doi.org/10.1074/jbc.m706579200}
}

@article{zheng2008-18279803,
  author  = {Zheng, L. T. and Ock, J. and Kwon, B. M. and Suk, K.},
  title   = {{Suppressive effects of flavonoid fisetin on lipopolysaccharide-induced microglial activation and neurotoxicity}},
  journal = {International immunopharmacology},
  year    = {2008},
  doi     = {10.1016/j.intimp.2007.12.012},
  pmid    = {18279803},
  url     = {https://doi.org/10.1016/j.intimp.2007.12.012}
}

@article{hook2008-18184658,
  author  = {Hook, V. Y. and Kindy, M. and Hook, G.},
  title   = {{Inhibitors of cathepsin B improve memory and reduce beta-amyloid in transgenic Alzheimer disease mice expressing the wild-type, but not the Swedish mutant, beta-secretase site of the amyloid precursor protein}},
  journal = {The Journal of biological chemistry},
  year    = {2008},
  doi     = {10.1074/jbc.m708362200},
  pmid    = {18184658},
  url     = {https://doi.org/10.1074/jbc.m708362200}
}

@article{parachikova2008-18258444,
  author  = {Parachikova, A. and Nichol, K. E. and Cotman, C. W.},
  title   = {{Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition}},
  journal = {Neurobiology of disease},
  year    = {2008},
  doi     = {10.1016/j.nbd.2007.12.008},
  pmid    = {18258444},
  url     = {https://doi.org/10.1016/j.nbd.2007.12.008}
}

@article{donnelly2008-18086681,
  author  = {Donnelly, P. S. and Caragounis, A. and Du, T. and Laughton, K. M. and Volitakis, I. and Cherny, R. A. and Sharples, R. A. and Hill, A. F. and others},
  title   = {{Selective intracellular release of copper and zinc ions from bis(thiosemicarbazonato) complexes reduces levels of Alzheimer disease amyloid-beta peptide}},
  journal = {The Journal of biological chemistry},
  year    = {2008},
  doi     = {10.1074/jbc.m705957200},
  pmid    = {18086681},
  url     = {https://doi.org/10.1074/jbc.m705957200}
}

@article{orimo2008-18079166,
  author  = {Orimo, S. and Uchihara, T. and Nakamura, A. and Mori, F. and Kakita, A. and Wakabayashi, K. and Takahashi, H.},
  title   = {{Axonal alpha-synuclein aggregates herald centripetal degeneration of cardiac sympathetic nerve in Parkinson's disease}},
  journal = {Brain : a journal of neurology},
  year    = {2008},
  doi     = {10.1093/brain/awm302},
  pmid    = {18079166},
  url     = {https://doi.org/10.1093/brain/awm302}
}

@article{verwer2007-18055496,
  author  = {Verwer, R. W. and Sluiter, A. A. and Balesar, R. A. and Baayen, J. C. and Noske, D. P. and Dirven, C. M. and Wouda, J. and van Dam, A. M. and others},
  title   = {{Mature astrocytes in the adult human neocortex express the early neuronal marker doublecortin}},
  journal = {Brain : a journal of neurology},
  year    = {2007},
  doi     = {10.1093/brain/awm264},
  pmid    = {18055496},
  url     = {https://doi.org/10.1093/brain/awm264}
}

@article{stevens2007-18083105,
  author  = {Stevens, Beth A. and Allen, Nicola J. and Vazquez, Luis E and Howell, Gareth R. and Christopherson, Karen S. and Nouri, Navid and Micheva, Kristina D. and Mehalow, Adrienne K. and Huberman, Andrew D. and Stafford, Benjamin K. and Sher, Alexander and Litke, Alan M and Lambris, John D. and Smith, Stephen J and John, Simon W. M. and Barres, Ben A.},
  title   = {{The Classical Complement Cascade Mediates CNS Synapse Elimination}},
  journal = {Cell},
  year    = {2007},
  doi     = {10.1016/j.cell.2007.10.036},
  pmid    = {18083105},
  url     = {https://doi.org/10.1016/j.cell.2007.10.036}
}

@article{mensah2007-18047653,
  author  = {Mensah, A. and Mulligan, C. and Linehan, J. and Ruf, S. and O'Doherty, A. and Grygalewicz, B. and Shipley, J. and Groet, J. and others},
  title   = {{An additional human chromosome 21 causes suppression of neural fate of pluripotent mouse embryonic stem cells in a teratoma model}},
  journal = {BMC developmental biology},
  year    = {2007},
  doi     = {10.1186/1471-213x-7-131},
  pmid    = {18047653},
  url     = {https://doi.org/10.1186/1471-213x-7-131}
}

@article{chaudhuri2008-18003888,
  author  = {Chaudhuri, A. and Yang, B. and Gendelman, H. E. and Persidsky, Y. and Kanmogne, G. D.},
  title   = {{STAT1 signaling modulates HIV-1-induced inflammatory responses and leukocyte transmigration across the blood-brain barrier}},
  journal = {Blood},
  year    = {2008},
  doi     = {10.1182/blood-2007-05-091207},
  pmid    = {18003888},
  url     = {https://doi.org/10.1182/blood-2007-05-091207}
}

@article{filimonenko2007-17984323,
  author  = {Filimonenko, M. and Stuffers, S. and Raiborg, C. and Yamamoto, A. and Malerød, L. and Fisher, E. M. and Isaacs, A. and Brech, A. and others},
  title   = {{Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease}},
  journal = {The Journal of cell biology},
  year    = {2007},
  doi     = {10.1083/jcb.200702115},
  pmid    = {17984323},
  url     = {https://doi.org/10.1083/jcb.200702115}
}

@article{milnerwood2007-17947312,
  author  = {Milnerwood, A. J. and Raymond, L. A.},
  title   = {{Corticostriatal synaptic function in mouse models of Huntington's disease: early effects of huntingtin repeat length and protein load}},
  journal = {The Journal of physiology},
  year    = {2007},
  doi     = {10.1113/jphysiol.2007.142448},
  pmid    = {17947312},
  url     = {https://doi.org/10.1113/jphysiol.2007.142448}
}

@article{cao2007-17942401,
  author  = {Cao, D. and Lu, H. and Lewis, T. L. and Li, L.},
  title   = {{Intake of sucrose-sweetened water induces insulin resistance and exacerbates memory deficits and amyloidosis in a transgenic mouse model of Alzheimer disease}},
  journal = {The Journal of biological chemistry},
  year    = {2007},
  doi     = {10.1074/jbc.m703561200},
  pmid    = {17942401},
  url     = {https://doi.org/10.1074/jbc.m703561200}
}

@article{bell2007-17913914,
  author  = {Bell, K. F. and Bennett, D. A. and Cuello, A. C.},
  title   = {{Paradoxical upregulation of glutamatergic presynaptic boutons during mild cognitive impairment}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2007},
  doi     = {10.1523/jneurosci.3269-07.2007},
  pmid    = {17913914},
  url     = {https://doi.org/10.1523/jneurosci.3269-07.2007}
}

@article{chen2007-18023959,
  author  = {Chen, J. F. and Sonsalla, P. K. and Pedata, F. and Melani, A. and Domenici, M. R. and Popoli, P. and Geiger, J. and Lopes, L. V. and others},
  title   = {{Adenosine A2A receptors and brain injury: broad spectrum of neuroprotection, multifaceted actions and "fine tuning" modulation}},
  journal = {Progress in neurobiology},
  year    = {2007},
  doi     = {10.1016/j.pneurobio.2007.09.002},
  pmid    = {18023959},
  url     = {https://doi.org/10.1016/j.pneurobio.2007.09.002}
}

@article{becker2008-17893702,
  author  = {Becker, C. and Zeau, B. and Rivat, C. and Blugeot, A. and Hamon, M. and Benoliel, J. J.},
  title   = {{Repeated social defeat-induced depression-like behavioral and biological alterations in rats: involvement of cholecystokinin}},
  journal = {Molecular psychiatry},
  year    = {2008},
  doi     = {10.1038/sj.mp.4002097},
  pmid    = {17893702},
  url     = {https://doi.org/10.1038/sj.mp.4002097}
}

@article{schmidt2007-17855360,
  author  = {Schmidt, V. and Sporbert, A. and Rohe, M. and Reimer, T. and Rehm, A. and Andersen, O. M. and Willnow, T. E.},
  title   = {{SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1}},
  journal = {The Journal of biological chemistry},
  year    = {2007},
  doi     = {10.1074/jbc.m705073200},
  pmid    = {17855360},
  url     = {https://doi.org/10.1074/jbc.m705073200}
}

@article{zhang2007-17898224,
  author  = {Zhang, Y. J. and Xu, Y. F. and Dickey, C. A. and Buratti, E. and Baralle, F. and Bailey, R. and Pickering-Brown, S. and Dickson, D. and others},
  title   = {{Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2007},
  doi     = {10.1523/jneurosci.3421-07.2007},
  pmid    = {17898224},
  url     = {https://doi.org/10.1523/jneurosci.3421-07.2007}
}

@article{lee2007-17683935,
  author  = {Lee, J. A. and Beigneux, A. and Ahmad, S. T. and Young, S. G. and Gao, F. B.},
  title   = {{ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration}},
  journal = {Current biology : CB},
  year    = {2007},
  doi     = {10.1016/j.cub.2007.07.029},
  pmid    = {17683935},
  url     = {https://doi.org/10.1016/j.cub.2007.07.029}
}

@article{asuni2007-17715348,
  author  = {Asuni, A. A. and Boutajangout, A. and Quartermain, D. and Sigurdsson, E. M.},
  title   = {{Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2007},
  doi     = {10.1523/jneurosci.2361-07.2007},
  pmid    = {17715348},
  url     = {https://doi.org/10.1523/jneurosci.2361-07.2007}
}

@article{ostrowski2007-17646164,
  author  = {Ostrowski, S. M. and Wilkinson, B. L. and Golde, T. E. and Landreth, G.},
  title   = {{Statins reduce amyloid-beta production through inhibition of protein isoprenylation}},
  journal = {The Journal of biological chemistry},
  year    = {2007},
  doi     = {10.1074/jbc.m702640200},
  pmid    = {17646164},
  url     = {https://doi.org/10.1074/jbc.m702640200}
}

@article{cairns2007-17591968,
  author  = {Cairns, N. J. and Neumann, M. and Bigio, E. H. and Holm, I. E. and Troost, D. and Hatanpaa, K. J. and Foong, C. and White, C. L. and others},
  title   = {{TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions}},
  journal = {The American journal of pathology},
  year    = {2007},
  doi     = {10.2353/ajpath.2007.070182},
  pmid    = {17591968},
  url     = {https://doi.org/10.2353/ajpath.2007.070182}
}

@article{rosenkranz2007-17582512,
  author  = {Rosenkranz, D. and Weyer, S. and Tolosa, E. and Gaenslen, A. and Berg, D. and Leyhe, T. and Gasser, T. and Stoltze, L.},
  title   = {{Higher frequency of regulatory T cells in the elderly and increased suppressive activity in neurodegeneration}},
  journal = {Journal of neuroimmunology},
  year    = {2007},
  doi     = {10.1016/j.jneuroim.2007.05.011},
  pmid    = {17582512},
  url     = {https://doi.org/10.1016/j.jneuroim.2007.05.011}
}

@article{sikk2007-17511846,
  author  = {Sikk, K. and Taba, P. and Haldre, S. and Bergquist, J. and Nyholm, D. and Zjablov, G. and Asser, T. and Aquilonius, S. M.},
  title   = {{Irreversible motor impairment in young addicts--ephedrone, manganism or both?}},
  journal = {Acta neurologica Scandinavica},
  year    = {2007},
  doi     = {10.1111/j.1600-0404.2007.00818.x},
  pmid    = {17511846},
  url     = {https://doi.org/10.1111/j.1600-0404.2007.00818.x}
}

@article{shaftel2007-17549256,
  author  = {Shaftel, S. S. and Kyrkanides, S. and Olschowka, J. A. and Miller, J. N. and Johnson, R. E. and O'Banion, M. K.},
  title   = {{Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology}},
  journal = {The Journal of clinical investigation},
  year    = {2007},
  doi     = {10.1172/jci31450},
  pmid    = {17549256},
  url     = {https://doi.org/10.1172/jci31450}
}

@article{rae2007-17597598,
  author  = {Rae, F. and Woods, K. and Sasmono, T. and Campanale, N. and Taylor, D. and Ovchinnikov, D. A. and Grimmond, S. M. and Hume, D. A. and others},
  title   = {{Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporter}},
  journal = {Developmental biology},
  year    = {2007},
  doi     = {10.1016/j.ydbio.2007.05.027},
  pmid    = {17597598},
  url     = {https://doi.org/10.1016/j.ydbio.2007.05.027}
}

@article{amadorortiz2007-17469117,
  author  = {Amador-Ortiz, C. and Lin, W. L. and Ahmed, Z. and Personett, D. and Davies, P. and Duara, R. and Graff-Radford, N. R. and Hutton, M. L. and others},
  title   = {{TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease}},
  journal = {Annals of neurology},
  year    = {2007},
  doi     = {10.1002/ana.21154},
  pmid    = {17469117},
  url     = {https://doi.org/10.1002/ana.21154}
}

@article{tampellini2007-17468102,
  author  = {Tampellini, D. and Magrané, J. and Takahashi, R. H. and Li, F. and Lin, M. T. and Almeida, C. G. and Gouras, G. K.},
  title   = {{Internalized antibodies to the Abeta domain of APP reduce neuronal Abeta and protect against synaptic alterations}},
  journal = {The Journal of biological chemistry},
  year    = {2007},
  doi     = {10.1074/jbc.m700373200},
  pmid    = {17468102},
  url     = {https://doi.org/10.1074/jbc.m700373200}
}

@article{green2007-17442823,
  author  = {Green, K. N. and Martinez-Coria, H. and Khashwji, H. and Hall, E. B. and Yurko-Mauro, K. A. and Ellis, L. and LaFerla, F. M.},
  title   = {{Dietary docosahexaenoic acid and docosapentaenoic acid ameliorate amyloid-beta and tau pathology via a mechanism involving presenilin 1 levels}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2007},
  doi     = {10.1523/jneurosci.0055-07.2007},
  pmid    = {17442823},
  url     = {https://doi.org/10.1523/jneurosci.0055-07.2007}
}

@article{hashimoto2007-17387318,
  author  = {Hashimoto, R. and Hashimoto, H. and Shintani, N. and Chiba, S. and Hattori, S. and Okada, T. and Nakajima, M. and Tanaka, K. and others},
  title   = {{Pituitary adenylate cyclase-activating polypeptide is associated with schizophrenia}},
  journal = {Molecular psychiatry},
  year    = {2007},
  doi     = {10.1038/sj.mp.4001982},
  pmid    = {17387318},
  url     = {https://doi.org/10.1038/sj.mp.4001982}
}

@article{westmark2007-17298186,
  author  = {Westmark, C. J. and Malter, J. S.},
  title   = {{FMRP mediates mGluR5-dependent translation of amyloid precursor protein}},
  journal = {PLoS biology},
  year    = {2007},
  doi     = {10.1371/journal.pbio.0050052},
  pmid    = {17298186},
  url     = {https://doi.org/10.1371/journal.pbio.0050052}
}

@article{garzon2007-17344400,
  author  = {Garzon, D. J. and Fahnestock, M.},
  title   = {{Oligomeric amyloid decreases basal levels of brain-derived neurotrophic factor (BDNF) mRNA via specific downregulation of BDNF transcripts IV and V in differentiated human neuroblastoma cells}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2007},
  doi     = {10.1523/jneurosci.5053-06.2007},
  pmid    = {17344400},
  url     = {https://doi.org/10.1523/jneurosci.5053-06.2007}
}

@article{medhurst2007-17327487,
  author  = {Medhurst, A. D. and Atkins, A. R. and Beresford, I. J. and Brackenborough, K. and Briggs, M. A. and Calver, A. R. and Cilia, J. and Cluderay, J. E. and others},
  title   = {{GSK189254, a novel H3 receptor antagonist that binds to histamine H3 receptors in Alzheimer's disease brain and improves cognitive performance in preclinical models}},
  journal = {The Journal of pharmacology and experimental therapeutics},
  year    = {2007},
  doi     = {10.1124/jpet.107.120311},
  pmid    = {17327487},
  url     = {https://doi.org/10.1124/jpet.107.120311}
}

@article{blard2007-17309878,
  author  = {Blard, O. and Feuillette, S. and Bou, J. and Chaumette, B. and Frébourg, T. and Campion, D. and Lecourtois, M.},
  title   = {{Cytoskeleton proteins are modulators of mutant tau-induced neurodegeneration in Drosophila}},
  journal = {Human molecular genetics},
  year    = {2007},
  doi     = {10.1093/hmg/ddm011},
  pmid    = {17309878},
  url     = {https://doi.org/10.1093/hmg/ddm011}
}

@article{kuhn2007-17307738,
  author  = {Kuhn, P. H. and Marjaux, E. and Imhof, A. and De Strooper, B. and Haass, C. and Lichtenthaler, S. F.},
  title   = {{Regulated intramembrane proteolysis of the interleukin-1 receptor II by alpha-, beta-, and gamma-secretase}},
  journal = {The Journal of biological chemistry},
  year    = {2007},
  doi     = {10.1074/jbc.m700356200},
  pmid    = {17307738},
  url     = {https://doi.org/10.1074/jbc.m700356200}
}

@article{zhang2007-17303576,
  author  = {Zhang, X. and Zhou, K. and Wang, R. and Cui, J. and Lipton, S. A. and Liao, F. F. and Xu, H. and Zhang, Y. W.},
  title   = {{Hypoxia-inducible factor 1alpha (HIF-1alpha)-mediated hypoxia increases BACE1 expression and beta-amyloid generation}},
  journal = {The Journal of biological chemistry},
  year    = {2007},
  doi     = {10.1074/jbc.m608856200},
  pmid    = {17303576},
  url     = {https://doi.org/10.1074/jbc.m608856200}
}

@article{yoshiyama2007-17270732,
  author  = {Yoshiyama, Yasumasa and Higuchi, Makoto and Zhang, Bin and Huang, Shu-Ming and Iwata, Nobuhisa and Saido, Takaomi C. and Maeda, Jun and Suhara, Tetsuya and Trojanowski, John Q. and Lee, Virginia M.‐Y.},
  title   = {{Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model}},
  journal = {Neuron},
  year    = {2007},
  doi     = {10.1016/j.neuron.2007.01.010},
  pmid    = {17270732},
  url     = {https://doi.org/10.1016/j.neuron.2007.01.010}
}

@article{neumann2007-17279000,
  author  = {Neumann, M. and Mackenzie, I. R. and Cairns, N. J. and Boyer, P. J. and Markesbery, W. R. and Smith, C. D. and Taylor, J. P. and Kretzschmar, H. A. and others},
  title   = {{TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations}},
  journal = {Journal of neuropathology and experimental neurology},
  year    = {2007},
  doi     = {10.1097/nen.0b013e31803020b9},
  pmid    = {17279000},
  url     = {https://doi.org/10.1097/nen.0b013e31803020b9}
}

@article{davidson2007-17219193,
  author  = {Davidson, Y. and Kelley, T. and Mackenzie, I. R. and Pickering-Brown, S. and Du Plessis, D. and Neary, D. and Snowden, J. S. and Mann, D. M.},
  title   = {{Ubiquitinated pathological lesions in frontotemporal lobar degeneration contain the TAR DNA-binding protein, TDP-43}},
  journal = {Acta neuropathologica},
  year    = {2007},
  doi     = {10.1007/s00401-006-0189-y},
  pmid    = {17219193},
  url     = {https://doi.org/10.1007/s00401-006-0189-y}
}

@article{dani2007-17009926,
  author  = {Dani, J. A. and Bertrand, D.},
  title   = {{Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system}},
  journal = {Annual review of pharmacology and toxicology},
  year    = {2007},
  doi     = {10.1146/annurev.pharmtox.47.120505.105214},
  pmid    = {17009926},
  url     = {https://doi.org/10.1146/annurev.pharmtox.47.120505.105214}
}

@article{carlson2007-17546681,
  author  = {Carlson, E. S. and Stead, J. D. and Neal, C. R. and Petryk, A. and Georgieff, M. K.},
  title   = {{Perinatal iron deficiency results in altered developmental expression of genes mediating energy metabolism and neuronal morphogenesis in hippocampus}},
  journal = {Hippocampus},
  year    = {2007},
  doi     = {10.1002/hipo.20307},
  pmid    = {17546681},
  url     = {https://doi.org/10.1002/hipo.20307}
}

@article{venneti2006-17156911,
  author  = {Venneti, S. and Lopresti, B. J. and Wiley, C. A.},
  title   = {{The peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: from pathology to imaging}},
  journal = {Progress in neurobiology},
  year    = {2006},
  doi     = {10.1016/j.pneurobio.2006.10.002},
  pmid    = {17156911},
  url     = {https://doi.org/10.1016/j.pneurobio.2006.10.002}
}

@article{xie2006-17234824,
  author  = {Xie, Z. and Dong, Y. and Maeda, U. and Moir, R. and Inouye, S. K. and Culley, D. J. and Crosby, G. and Tanzi, R. E.},
  title   = {{Isoflurane-induced apoptosis: a potential pathogenic link between delirium and dementia}},
  journal = {The journals of gerontology. Series A, Biological sciences and medical sciences},
  year    = {2006},
  doi     = {10.1093/gerona/61.12.1300},
  pmid    = {17234824},
  url     = {https://doi.org/10.1093/gerona/61.12.1300}
}

@article{ni2006-17115048,
  author  = {Ni, Y. and Zhao, X. and Bao, G. and Zou, L. and Teng, L. and Wang, Z. and Song, M. and Xiong, J. and others},
  title   = {{Activation of beta2-adrenergic receptor stimulates gamma-secretase activity and accelerates amyloid plaque formation}},
  journal = {Nature medicine},
  year    = {2006},
  doi     = {10.1038/nm1485},
  pmid    = {17115048},
  url     = {https://doi.org/10.1038/nm1485}
}

@article{mclarnon2006-17086106,
  author  = {McLarnon, J. G. and Ryu, J. K. and Walker, D. G. and Choi, H. B.},
  title   = {{Upregulated expression of purinergic P2X(7) receptor in Alzheimer disease and amyloid-beta peptide-treated microglia and in peptide-injected rat hippocampus}},
  journal = {Journal of neuropathology and experimental neurology},
  year    = {2006},
  doi     = {10.1097/01.jnen.0000240470.97295.d3},
  pmid    = {17086106},
  url     = {https://doi.org/10.1097/01.jnen.0000240470.97295.d3}
}

@article{arai2006-17084815,
  author  = {Arai, T. and Hasegawa, M. and Akiyama, H. and Ikeda, K. and Nonaka, T. and Mori, H. and Mann, D. and Tsuchiya, K. and others},
  title   = {{TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis}},
  journal = {Biochemical and biophysical research communications},
  year    = {2006},
  doi     = {10.1016/j.bbrc.2006.10.093},
  pmid    = {17084815},
  url     = {https://doi.org/10.1016/j.bbrc.2006.10.093}
}

@article{engel2006-17059563,
  author  = {Engel, T. and Goñi-Oliver, P. and Lucas, J. J. and Avila, J. and Hernández, F.},
  title   = {{Chronic lithium administration to FTDP-17 tau and GSK-3beta overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre-formed neurofibrillary tangles do not revert}},
  journal = {Journal of neurochemistry},
  year    = {2006},
  doi     = {10.1111/j.1471-4159.2006.04139.x},
  pmid    = {17059563},
  url     = {https://doi.org/10.1111/j.1471-4159.2006.04139.x}
}

@article{oddo2006-17056594,
  author  = {Oddo, S. and Vasilevko, V. and Caccamo, A. and Kitazawa, M. and Cribbs, D. H. and LaFerla, F. M.},
  title   = {{Reduction of soluble Abeta and tau, but not soluble Abeta alone, ameliorates cognitive decline in transgenic mice with plaques and tangles}},
  journal = {The Journal of biological chemistry},
  year    = {2006},
  doi     = {10.1074/jbc.m608485200},
  pmid    = {17056594},
  url     = {https://doi.org/10.1074/jbc.m608485200}
}

@article{wen2007-17113760,
  author  = {Wen, Y. and Yang, S. H. and Liu, R. and Perez, E. J. and Brun-Zinkernagel, A. M. and Koulen, P. and Simpkins, J. W.},
  title   = {{Cdk5 is involved in NFT-like tauopathy induced by transient cerebral ischemia in female rats}},
  journal = {Biochimica et biophysica acta},
  year    = {2007},
  doi     = {10.1016/j.bbadis.2006.10.011},
  pmid    = {17113760},
  url     = {https://doi.org/10.1016/j.bbadis.2006.10.011}
}

@article{dunfee2006-17015824,
  author  = {Dunfee, R. L. and Thomas, E. R. and Gorry, P. R. and Wang, J. and Taylor, J. and Kunstman, K. and Wolinsky, S. M. and Gabuzda, D.},
  title   = {{The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2006},
  doi     = {10.1073/pnas.0605513103},
  pmid    = {17015824},
  url     = {https://doi.org/10.1073/pnas.0605513103}
}

@article{neumann2006-17023659,
  author  = {Neumann, M. and Sampathu, D. M. and Kwong, L. K. and Truax, A. C. and Micsenyi, M. C. and Chou, T. T. and Bruce, J. and Schuck, T. and others},
  title   = {{Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis}},
  journal = {Science (New York, N.Y.)},
  year    = {2006},
  doi     = {10.1126/science.1134108},
  pmid    = {17023659},
  url     = {https://doi.org/10.1126/science.1134108}
}

@article{zerbinatti2006-17012232,
  author  = {Zerbinatti, C. V. and Wahrle, S. E. and Kim, H. and Cam, J. A. and Bales, K. and Paul, S. M. and Holtzman, D. M. and Bu, G.},
  title   = {{Apolipoprotein E and low density lipoprotein receptor-related protein facilitate intraneuronal Abeta42 accumulation in amyloid model mice}},
  journal = {The Journal of biological chemistry},
  year    = {2006},
  doi     = {10.1074/jbc.m604436200},
  pmid    = {17012232},
  url     = {https://doi.org/10.1074/jbc.m604436200}
}

@article{colton2006-17005052,
  author  = {Colton, C. A. and Mott, R. T. and Sharpe, H. and Xu, Q. and Van Nostrand, W. E. and Vitek, M. P.},
  title   = {{Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD}},
  journal = {Journal of neuroinflammation},
  year    = {2006},
  doi     = {10.1186/1742-2094-3-27},
  pmid    = {17005052},
  url     = {https://doi.org/10.1186/1742-2094-3-27}
}

@article{kim2006-16959772,
  author  = {Kim, E. J. and Sung, J. Y. and Lee, H. J. and Rhim, H. and Hasegawa, M. and Iwatsubo, T. and Min do, S. and Kim, J. and others},
  title   = {{Dyrk1A phosphorylates alpha-synuclein and enhances intracellular inclusion formation}},
  journal = {The Journal of biological chemistry},
  year    = {2006},
  doi     = {10.1074/jbc.m606147200},
  pmid    = {16959772},
  url     = {https://doi.org/10.1074/jbc.m606147200}
}

@article{gass2006-16950801,
  author  = {Gass, J. and Cannon, A. and Mackenzie, I. R. and Boeve, B. and Baker, M. and Adamson, J. and Crook, R. and Melquist, S. and others},
  title   = {{Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration}},
  journal = {Human molecular genetics},
  year    = {2006},
  doi     = {10.1093/hmg/ddl241},
  pmid    = {16950801},
  url     = {https://doi.org/10.1093/hmg/ddl241}
}

@article{veereshwarayya2006-16887805,
  author  = {Veereshwarayya, V. and Kumar, P. and Rosen, K. M. and Mestril, R. and Querfurth, H. W.},
  title   = {{Differential effects of mitochondrial heat shock protein 60 and related molecular chaperones to prevent intracellular beta-amyloid-induced inhibition of complex IV and limit apoptosis}},
  journal = {The Journal of biological chemistry},
  year    = {2006},
  doi     = {10.1074/jbc.m602533200},
  pmid    = {16887805},
  url     = {https://doi.org/10.1074/jbc.m602533200}
}

@article{kelly2006-16864575,
  author  = {Kelly, B. L. and Ferreira, A.},
  title   = {{beta-Amyloid-induced dynamin 1 degradation is mediated by N-methyl-D-aspartate receptors in hippocampal neurons}},
  journal = {The Journal of biological chemistry},
  year    = {2006},
  doi     = {10.1074/jbc.m605081200},
  pmid    = {16864575},
  url     = {https://doi.org/10.1074/jbc.m605081200}
}

@article{anderson2006-16847063,
  author  = {Anderson, J. P. and Walker, D. E. and Goldstein, J. M. and de Laat, R. and Banducci, K. and Caccavello, R. J. and Barbour, R. and Huang, J. and others},
  title   = {{Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease}},
  journal = {The Journal of biological chemistry},
  year    = {2006},
  doi     = {10.1074/jbc.m600933200},
  pmid    = {16847063},
  url     = {https://doi.org/10.1074/jbc.m600933200}
}

@article{cruts2006-16862115,
  author  = {Cruts, M. and Gijselinck, I. and van der Zee, J. and Engelborghs, S. and Wils, H. and Pirici, D. and Rademakers, R. and others},
  title   = {{Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21}},
  journal = {Nature},
  year    = {2006},
  doi     = {10.1038/nature05017},
  pmid    = {16862115},
  url     = {https://doi.org/10.1038/nature05017}
}

@article{tolia2006-16844686,
  author  = {Tolia, A. and Chávez-Gutiérrez, L. and De Strooper, B.},
  title   = {{Contribution of presenilin transmembrane domains 6 and 7 to a water-containing cavity in the gamma-secretase complex}},
  journal = {The Journal of biological chemistry},
  year    = {2006},
  doi     = {10.1074/jbc.m604997200},
  pmid    = {16844686},
  url     = {https://doi.org/10.1074/jbc.m604997200}
}

@article{cenciarelli2006-16808880,
  author  = {Cenciarelli, C. and Budoni, M. and Mercanti, D. and Fernandez, E. and Pallini, R. and Aloe, L. and Cimino, V. and Maira, G. and others},
  title   = {{In vitro analysis of mouse neural stem cells genetically modified to stably express human NGF by a novel multigenic viral expression system}},
  journal = {Neurological research},
  year    = {2006},
  doi     = {10.1179/016164106x115161},
  pmid    = {16808880},
  url     = {https://doi.org/10.1179/016164106x115161}
}

@article{culbert2006-16774924,
  author  = {Culbert, A. A. and Skaper, S. D. and Howlett, D. R. and Evans, N. A. and Facci, L. and Soden, P. E. and Seymour, Z. M. and Guillot, F. and others},
  title   = {{MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease}},
  journal = {The Journal of biological chemistry},
  year    = {2006},
  doi     = {10.1074/jbc.m513646200},
  pmid    = {16774924},
  url     = {https://doi.org/10.1074/jbc.m513646200}
}

@article{takeuchi2006-16720574,
  author  = {Takeuchi, H. and Jin, S. and Wang, J. and Zhang, G. and Kawanokuchi, J. and Kuno, R. and Sonobe, Y. and Mizuno, T. and others},
  title   = {{Tumor necrosis factor-alpha induces neurotoxicity via glutamate release from hemichannels of activated microglia in an autocrine manner}},
  journal = {The Journal of biological chemistry},
  year    = {2006},
  doi     = {10.1074/jbc.m600504200},
  pmid    = {16720574},
  url     = {https://doi.org/10.1074/jbc.m600504200}
}

@article{chong2006-16714296,
  author  = {Chong, Y. H. and Shin, Y. J. and Lee, E. O. and Kayed, R. and Glabe, C. G. and Tenner, A. J.},
  title   = {{ERK1/2 activation mediates Abeta oligomer-induced neurotoxicity via caspase-3 activation and tau cleavage in rat organotypic hippocampal slice cultures}},
  journal = {The Journal of biological chemistry},
  year    = {2006},
  doi     = {10.1074/jbc.m601016200},
  pmid    = {16714296},
  url     = {https://doi.org/10.1074/jbc.m601016200}
}

@article{saha2006-16771683,
  author  = {Saha, R. N. and Pahan, K.},
  title   = {{Regulation of inducible nitric oxide synthase gene in glial cells}},
  journal = {Antioxidants \& redox signaling},
  year    = {2006},
  doi     = {10.1089/ars.2006.8.929},
  pmid    = {16771683},
  url     = {https://doi.org/10.1089/ars.2006.8.929}
}

@article{xie2006-16645451,
  author  = {Xie, Z. and Dong, Y. and Maeda, U. and Alfille, P. and Culley, D. J. and Crosby, G. and Tanzi, R. E.},
  title   = {{The common inhalation anesthetic isoflurane induces apoptosis and increases amyloid beta protein levels}},
  journal = {Anesthesiology},
  year    = {2006},
  doi     = {10.1097/00000542-200605000-00015},
  pmid    = {16645451},
  url     = {https://doi.org/10.1097/00000542-200605000-00015}
}

@article{wang2006-16645044,
  author  = {Wang, R. and Zhang, Y. W. and Zhang, X. and Liu, R. and Hong, S. and Xia, K. and Xia, J. and others},
  title   = {{Transcriptional regulation of APH-1A and increased gamma-secretase cleavage of APP and Notch by HIF-1 and hypoxia}},
  journal = {FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year    = {2006},
  doi     = {10.1096/fj.06-5839fje},
  pmid    = {16645044},
  url     = {https://doi.org/10.1096/fj.06-5839fje}
}

@article{huang2006-16636059,
  author  = {Huang, S. M. and Mouri, A. and Kokubo, H. and Nakajima, R. and Suemoto, T. and Higuchi, M. and Staufenbiel, M. and Noda, Y. and others},
  title   = {{Neprilysin-sensitive synapse-associated amyloid-beta peptide oligomers impair neuronal plasticity and cognitive function}},
  journal = {The Journal of biological chemistry},
  year    = {2006},
  doi     = {10.1074/jbc.m601372200},
  pmid    = {16636059},
  url     = {https://doi.org/10.1074/jbc.m601372200}
}

@article{obregon2006-16624814,
  author  = {Obregon, D. F. and Rezai-Zadeh, K. and Bai, Y. and Sun, N. and Hou, H. and Ehrhart, J. and Zeng, J. and Mori, T. and others},
  title   = {{ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein}},
  journal = {The Journal of biological chemistry},
  year    = {2006},
  doi     = {10.1074/jbc.m600617200},
  pmid    = {16624814},
  url     = {https://doi.org/10.1074/jbc.m600617200}
}

@article{galimberti2006-16606766,
  author  = {Galimberti, D. and Schoonenboom, N. and Scheltens, P. and Fenoglio, C. and Bouwman, F. and Venturelli, E. and Guidi, I. and Blankenstein, M. A. and others},
  title   = {{Intrathecal chemokine synthesis in mild cognitive impairment and Alzheimer disease}},
  journal = {Archives of neurology},
  year    = {2006},
  doi     = {10.1001/archneur.63.4.538},
  pmid    = {16606766},
  url     = {https://doi.org/10.1001/archneur.63.4.538}
}

@article{ginsberg2006-16539663,
  author  = {Ginsberg, S. D. and Che, S. and Wuu, J. and Counts, S. E. and Mufson, E. J.},
  title   = {{Down regulation of trk but not p75NTR gene expression in single cholinergic basal forebrain neurons mark the progression of Alzheimer's disease}},
  journal = {Journal of neurochemistry},
  year    = {2006},
  doi     = {10.1111/j.1471-4159.2006.03764.x},
  pmid    = {16539663},
  url     = {https://doi.org/10.1111/j.1471-4159.2006.03764.x}
}

@article{abildayeva2006-16524875,
  author  = {Abildayeva, K. and Jansen, P. J. and Hirsch-Reinshagen, V. and Bloks, V. W. and Bakker, A. H. and Ramaekers, F. C. and de Vente, J. and Groen, A. K. and others},
  title   = {{24(S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux}},
  journal = {The Journal of biological chemistry},
  year    = {2006},
  doi     = {10.1074/jbc.m601019200},
  pmid    = {16524875},
  url     = {https://doi.org/10.1074/jbc.m601019200}
}

@article{butterfield2006-16413966,
  author  = {Butterfield, D. A. and Reed, T. and Perluigi, M. and De Marco, C. and Coccia, R. and Cini, C. and Sultana, R.},
  title   = {{Elevated protein-bound levels of the lipid peroxidation product, 4-hydroxy-2-nonenal, in brain from persons with mild cognitive impairment}},
  journal = {Neuroscience letters},
  year    = {2006},
  doi     = {10.1016/j.neulet.2005.12.017},
  pmid    = {16413966},
  url     = {https://doi.org/10.1016/j.neulet.2005.12.017}
}

@article{williams2006-17118264,
  author  = {Williams, A. and Jahreiss, L. and Sarkar, S. and Saiki, S. and Menzies, F. M. and Ravikumar, B. and Rubinsztein, D. C.},
  title   = {{Aggregate-prone proteins are cleared from the cytosol by autophagy: therapeutic implications}},
  journal = {Current topics in developmental biology},
  year    = {2006},
  doi     = {10.1016/s0070-2153(06)76003-3},
  pmid    = {17118264},
  url     = {https://doi.org/10.1016/s0070-2153(06)76003-3}
}

@article{eugenin2006-16436595,
  author  = {Eugenin, E. A. and Osiecki, K. and Lopez, L. and Goldstein, H. and Calderon, T. M. and Berman, J. W.},
  title   = {{CCL2/monocyte chemoattractant protein-1 mediates enhanced transmigration of human immunodeficiency virus (HIV)-infected leukocytes across the blood-brain barrier: a potential mechanism of HIV-CNS invasion and NeuroAIDS}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2006},
  doi     = {10.1523/jneurosci.3863-05.2006},
  pmid    = {16436595},
  url     = {https://doi.org/10.1523/jneurosci.3863-05.2006}
}

@article{berger2006-16368705,
  author  = {Berger, Z. and Ravikumar, B. and Menzies, F. M. and Oroz, L. G. and Underwood, B. R. and Pangalos, M. N. and Schmitt, I. and Wullner, U. and others},
  title   = {{Rapamycin alleviates toxicity of different aggregate-prone proteins}},
  journal = {Human molecular genetics},
  year    = {2006},
  doi     = {10.1093/hmg/ddi458},
  pmid    = {16368705},
  url     = {https://doi.org/10.1093/hmg/ddi458}
}

@article{cirrito2005-16364896,
  author  = {Cirrito, John R. and Yamada, Kelvin A. and Finn, Mary Beth and Sloviter, Robert S. and Bales, Kelly R. and May, Patrick C. and Schoepp, Darryle D. and Paul, Steven M. and Mennerick, Steven J. and Holtzman, David M.},
  title   = {{Synaptic Activity Regulates Interstitial Fluid Amyloid-β Levels In Vivo}},
  journal = {Neuron},
  year    = {2005},
  doi     = {10.1016/j.neuron.2005.10.028},
  pmid    = {16364896},
  url     = {https://doi.org/10.1016/j.neuron.2005.10.028}
}

@article{greig2005-16275899,
  author  = {Greig, N. H. and Utsuki, T. and Ingram, D. K. and Wang, Y. and Pepeu, G. and Scali, C. and Yu, Q. S. and Mamczarz, J. and others},
  title   = {{Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2005},
  doi     = {10.1073/pnas.0508575102},
  pmid    = {16275899},
  url     = {https://doi.org/10.1073/pnas.0508575102}
}

@article{zatta2005-16308479,
  author  = {Zatta, P. and Zambenedetti, P. and Musicco, M. and Adorni, F.},
  title   = {{Metallothionein-I-II and GFAP positivity in the brains from frontotemporal dementia patients}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2005},
  doi     = {10.3233/jad-2005-8203},
  pmid    = {16308479},
  url     = {https://doi.org/10.3233/jad-2005-8203}
}

@article{cao2006-16236385,
  author  = {Cao, D. and Fukuchi, K. and Wan, H. and Kim, H. and Li, L.},
  title   = {{Lack of LDL receptor aggravates learning deficits and amyloid deposits in Alzheimer transgenic mice}},
  journal = {Neurobiology of aging},
  year    = {2006},
  doi     = {10.1016/j.neurobiolaging.2005.09.011},
  pmid    = {16236385},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2005.09.011}
}

@article{lukiw2005-16151530,
  author  = {Lukiw, W. J. and Cui, J. G. and Marcheselli, V. L. and Bodker, M. and Botkjaer, A. and Gotlinger, K. and Serhan, C. N. and Bazan, N. G.},
  title   = {{A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease}},
  journal = {The Journal of clinical investigation},
  year    = {2005},
  doi     = {10.1172/jci25420},
  pmid    = {16151530},
  url     = {https://doi.org/10.1172/jci25420}
}

@article{yoshiyama2005-16238489,
  author  = {Yoshiyama, Y. and Uryu, K. and Higuchi, M. and Longhi, L. and Hoover, R. and Fujimoto, S. and McIntosh, T. and Lee, V. M. and others},
  title   = {{Enhanced neurofibrillary tangle formation, cerebral atrophy, and cognitive deficits induced by repetitive mild brain injury in a transgenic tauopathy mouse model}},
  journal = {Journal of neurotrauma},
  year    = {2005},
  doi     = {10.1089/neu.2005.22.1134},
  pmid    = {16238489},
  url     = {https://doi.org/10.1089/neu.2005.22.1134}
}

@article{fishel2005-16216936,
  author  = {Fishel, M. A. and Watson, G. S. and Montine, T. J. and Wang, Q. and Green, P. S. and Kulstad, J. J. and Cook, D. G. and Peskind, E. R. and others},
  title   = {{Hyperinsulinemia provokes synchronous increases in central inflammation and beta-amyloid in normal adults}},
  journal = {Archives of neurology},
  year    = {2005},
  doi     = {10.1001/archneur.62.10.noc50112},
  pmid    = {16216936},
  url     = {https://doi.org/10.1001/archneur.62.10.noc50112}
}

@article{chen2005-16183991,
  author  = {Chen, J. and Zhou, Y. and Mueller-Steiner, S. and Chen, L. F. and Kwon, H. and Yi, S. and Mucke, L. and Gan, L.},
  title   = {{SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling}},
  journal = {The Journal of biological chemistry},
  year    = {2005},
  doi     = {10.1074/jbc.m509329200},
  pmid    = {16183991},
  url     = {https://doi.org/10.1074/jbc.m509329200}
}

@article{desire2005-16150730,
  author  = {Désiré, L. and Bourdin, J. and Loiseau, N. and Peillon, H. and Picard, V. and De Oliveira, C. and Bachelot, F. and Leblond, B. and others},
  title   = {{RAC1 inhibition targets amyloid precursor protein processing by gamma-secretase and decreases Abeta production in vitro and in vivo}},
  journal = {The Journal of biological chemistry},
  year    = {2005},
  doi     = {10.1074/jbc.m507913200},
  pmid    = {16150730},
  url     = {https://doi.org/10.1074/jbc.m507913200}
}

@article{rezaizadeh2005-16177050,
  author  = {Rezai-Zadeh, K. and Shytle, D. and Sun, N. and Mori, T. and Hou, H. and Jeanniton, D. and Ehrhart, J. and Townsend, K. and others},
  title   = {{Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2005},
  doi     = {10.1523/jneurosci.1521-05.2005},
  pmid    = {16177050},
  url     = {https://doi.org/10.1523/jneurosci.1521-05.2005}
}

@article{cordle2005-16085653,
  author  = {Cordle, A. and Koenigsknecht-Talboo, J. and Wilkinson, B. and Limpert, A. and Landreth, G.},
  title   = {{Mechanisms of statin-mediated inhibition of small G-protein function}},
  journal = {The Journal of biological chemistry},
  year    = {2005},
  doi     = {10.1074/jbc.m505268200},
  pmid    = {16085653},
  url     = {https://doi.org/10.1074/jbc.m505268200}
}

@article{miravalle2005-16086583,
  author  = {Miravalle, L. and Calero, M. and Takao, M. and Roher, A. E. and Ghetti, B. and Vidal, R.},
  title   = {{Amino-terminally truncated Abeta peptide species are the main component of cotton wool plaques}},
  journal = {Biochemistry},
  year    = {2005},
  doi     = {10.1021/bi0508237},
  pmid    = {16086583},
  url     = {https://doi.org/10.1021/bi0508237}
}

@article{miao2005-16049335,
  author  = {Miao, J. and Xu, F. and Davis, J. and Otte-Höller, I. and Verbeek, M. M. and Van Nostrand, W. E.},
  title   = {{Cerebral microvascular amyloid beta protein deposition induces vascular degeneration and neuroinflammation in transgenic mice expressing human vasculotropic mutant amyloid beta precursor protein}},
  journal = {The American journal of pathology},
  year    = {2005},
  doi     = {10.1016/s0002-9440(10)62993-8},
  pmid    = {16049335},
  url     = {https://doi.org/10.1016/s0002-9440(10)62993-8}
}

@article{skibinski2005-16041373,
  author  = {Skibinski, G. and Parkinson, N. J. and Brown, J. M. and Chakrabarti, L. and Lloyd, S. L. and Hummerich, H. and Nielsen, J. E. and Hodges, JR. and others},
  title   = {{Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia}},
  journal = {Nature genetics},
  year    = {2005},
  doi     = {10.1038/ng1609},
  pmid    = {16041373},
  url     = {https://doi.org/10.1038/ng1609}
}

@article{kang2005-15927426,
  author  = {Kang, D. C. and Su, Z. Z. and Sarkar, D. and Emdad, L. and Volsky, D. J. and Fisher, P. B.},
  title   = {{Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1}},
  journal = {Gene},
  year    = {2005},
  doi     = {10.1016/j.gene.2005.04.006},
  pmid    = {15927426},
  url     = {https://doi.org/10.1016/j.gene.2005.04.006}
}

@article{masliah2005-15953415,
  author  = {Masliah, E. and Rockenstein, E. and Adame, A. and Alford, M. and Crews, L. and Hashimoto, M. and Seubert, P. and Lee, M. and others},
  title   = {{Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease}},
  journal = {Neuron},
  year    = {2005},
  doi     = {10.1016/j.neuron.2005.05.010},
  pmid    = {15953415},
  url     = {https://doi.org/10.1016/j.neuron.2005.05.010}
}

@article{tamboli2005-15923191,
  author  = {Tamboli, I. Y. and Prager, K. and Barth, E. and Heneka, M. and Sandhoff, K. and Walter, J.},
  title   = {{Inhibition of glycosphingolipid biosynthesis reduces secretion of the beta-amyloid precursor protein and amyloid beta-peptide}},
  journal = {The Journal of biological chemistry},
  year    = {2005},
  doi     = {10.1074/jbc.m414525200},
  pmid    = {15923191},
  url     = {https://doi.org/10.1074/jbc.m414525200}
}

@article{fryer2005-15888448,
  author  = {Fryer, J. D. and Demattos, R. B. and McCormick, L. M. and O'Dell, M. A. and Spinner, M. L. and Bales, K. R. and Paul, S. M. and Sullivan, P. M. and others},
  title   = {{The low density lipoprotein receptor regulates the level of central nervous system human and murine apolipoprotein E but does not modify amyloid plaque pathology in PDAPP mice}},
  journal = {The Journal of biological chemistry},
  year    = {2005},
  doi     = {10.1074/jbc.m502143200},
  pmid    = {15888448},
  url     = {https://doi.org/10.1074/jbc.m502143200}
}

@article{wong2005-15824102,
  author  = {Wong, H. K. and Sakurai, T. and Oyama, F. and Kaneko, K. and Wada, K. and Miyazaki, H. and Kurosawa, M. and De Strooper, B. and others},
  title   = {{beta Subunits of voltage-gated sodium channels are novel substrates of beta-site amyloid precursor protein-cleaving enzyme (BACE1) and gamma-secretase}},
  journal = {The Journal of biological chemistry},
  year    = {2005},
  doi     = {10.1074/jbc.m414648200},
  pmid    = {15824102},
  url     = {https://doi.org/10.1074/jbc.m414648200}
}

@article{lunamedina2005-15817469,
  author  = {Luna-Medina, R. and Cortes-Canteli, M. and Alonso, M. and Santos, A. and Martínez, A. and Perez-Castillo, A.},
  title   = {{Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator-activated receptor gamma activation}},
  journal = {The Journal of biological chemistry},
  year    = {2005},
  doi     = {10.1074/jbc.m414390200},
  pmid    = {15817469},
  url     = {https://doi.org/10.1074/jbc.m414390200}
}

@article{saito2005-15778722,
  author  = {Saito, T. and Iwata, N. and Tsubuki, S. and Takaki, Y. and Takano, J. and Huang, S. M. and Suemoto, T. and Higuchi, M. and others},
  title   = {{Somatostatin regulates brain amyloid beta peptide Abeta42 through modulation of proteolytic degradation}},
  journal = {Nature medicine},
  year    = {2005},
  doi     = {10.1038/nm1206},
  pmid    = {15778722},
  url     = {https://doi.org/10.1038/nm1206}
}

@article{camden2005-15778502,
  author  = {Camden, J. M. and Schrader, A. M. and Camden, R. E. and González, F. A. and Erb, L. and Seye, C. I. and Weisman, G. A.},
  title   = {{P2Y2 nucleotide receptors enhance alpha-secretase-dependent amyloid precursor protein processing}},
  journal = {The Journal of biological chemistry},
  year    = {2005},
  doi     = {10.1074/jbc.m500219200},
  pmid    = {15778502},
  url     = {https://doi.org/10.1074/jbc.m500219200}
}

@article{vonarnim2005-15749709,
  author  = {von Arnim, C. A. and Kinoshita, A. and Peltan, I. D. and Tangredi, M. M. and Herl, L. and Lee, B. M. and Spoelgen, R. and Hshieh, T. T. and others},
  title   = {{The low density lipoprotein receptor-related protein (LRP) is a novel beta-secretase (BACE1) substrate}},
  journal = {The Journal of biological chemistry},
  year    = {2005},
  doi     = {10.1074/jbc.m414248200},
  pmid    = {15749709},
  url     = {https://doi.org/10.1074/jbc.m414248200}
}

@article{angeletti2005-15722349,
  author  = {Angeletti, B. and Waldron, K. J. and Freeman, K. B. and Bawagan, H. and Hussain, I. and Miller, C. C. and Lau, K. F. and Tennant, M. E. and others},
  title   = {{BACE1 cytoplasmic domain interacts with the copper chaperone for superoxide dismutase-1 and binds copper}},
  journal = {The Journal of biological chemistry},
  year    = {2005},
  doi     = {10.1074/jbc.m412034200},
  pmid    = {15722349},
  url     = {https://doi.org/10.1074/jbc.m412034200}
}

@article{cole2005-15718241,
  author  = {Cole, S. L. and Grudzien, A. and Manhart, I. O. and Kelly, B. L. and Oakley, H. and Vassar, R.},
  title   = {{Statins cause intracellular accumulation of amyloid precursor protein, beta-secretase-cleaved fragments, and amyloid beta-peptide via an isoprenoid-dependent mechanism}},
  journal = {The Journal of biological chemistry},
  year    = {2005},
  doi     = {10.1074/jbc.m413895200},
  pmid    = {15718241},
  url     = {https://doi.org/10.1074/jbc.m413895200}
}

@article{zhang2005-15711015,
  author  = {Zhang, Y. W. and Luo, W. J. and Wang, H. and Lin, P. and Vetrivel, K. S. and Liao, F. and Li, F. and Wong, P. C. and others},
  title   = {{Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components}},
  journal = {The Journal of biological chemistry},
  year    = {2005},
  doi     = {10.1074/jbc.m409467200},
  pmid    = {15711015},
  url     = {https://doi.org/10.1074/jbc.m409467200}
}

@article{brendza2005-15668737,
  author  = {Brendza, R. P. and Bacskai, B. J. and Cirrito, JR. and Simmons, K. A. and Skoch, J. M. and Klunk, W. E. and Mathis, C. A. and Bales, K. R. and others},
  title   = {{Anti-Abeta antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice}},
  journal = {The Journal of clinical investigation},
  year    = {2005},
  doi     = {10.1172/jci23269},
  pmid    = {15668737},
  url     = {https://doi.org/10.1172/jci23269}
}

@article{cartier2005-15708626,
  author  = {Cartier, L. and Hartley, O. and Dubois-Dauphin, M. and Krause, K. H.},
  title   = {{Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases}},
  journal = {Brain research. Brain research reviews},
  year    = {2005},
  doi     = {10.1016/j.brainresrev.2004.07.021},
  pmid    = {15708626},
  url     = {https://doi.org/10.1016/j.brainresrev.2004.07.021}
}

@article{takahashi2005-15728241,
  author  = {Takahashi, K. and Rochford, C. D. and Neumann, H.},
  title   = {{Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2}},
  journal = {The Journal of experimental medicine},
  year    = {2005},
  doi     = {10.1084/jem.20041611},
  pmid    = {15728241},
  url     = {https://doi.org/10.1084/jem.20041611}
}

@article{zhang2005-15649487,
  author  = {Zhang, X. and Dong, F. and Ren, J. and Driscoll, M. J. and Culver, B.},
  title   = {{High dietary fat induces NADPH oxidase-associated oxidative stress and inflammation in rat cerebral cortex}},
  journal = {Experimental neurology},
  year    = {2005},
  doi     = {10.1016/j.expneurol.2004.10.011},
  pmid    = {15649487},
  url     = {https://doi.org/10.1016/j.expneurol.2004.10.011}
}

@article{lim2005-15728840,
  author  = {Lim, K. L. and Chew, K. C. and Tan, J. M. and Wang, C. and Chung, K. K. and Zhang, Y. and Tanaka, Y. and Smith, W. and others},
  title   = {{Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2005},
  doi     = {10.1523/jneurosci.4474-04.2005},
  pmid    = {15728840},
  url     = {https://doi.org/10.1523/jneurosci.4474-04.2005}
}

@article{takeuchi2005-15640150,
  author  = {Takeuchi, H. and Mizuno, T. and Zhang, G. and Wang, J. and Kawanokuchi, J. and Kuno, R. and Suzumura, A.},
  title   = {{Neuritic beading induced by activated microglia is an early feature of neuronal dysfunction toward neuronal death by inhibition of mitochondrial respiration and axonal transport}},
  journal = {The Journal of biological chemistry},
  year    = {2005},
  doi     = {10.1074/jbc.m413863200},
  pmid    = {15640150},
  url     = {https://doi.org/10.1074/jbc.m413863200}
}

@article{youdim2005-15573406,
  author  = {Youdim, M. B. and Bar Am, O. and Yogev-Falach, M. and Weinreb, O. and Maruyama, W. and Naoi, M. and Amit, T.},
  title   = {{Rasagiline: neurodegeneration, neuroprotection, and mitochondrial permeability transition}},
  journal = {Journal of neuroscience research},
  year    = {2005},
  doi     = {10.1002/jnr.20350},
  pmid    = {15573406},
  url     = {https://doi.org/10.1002/jnr.20350}
}

@article{fuso2005-15607954,
  author  = {Fuso, A. and Seminara, L. and Cavallaro, R. A. and D'Anselmi, F. and Scarpa, S.},
  title   = {{S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and beta-amyloid production}},
  journal = {Molecular and cellular neurosciences},
  year    = {2005},
  doi     = {10.1016/j.mcn.2004.09.007},
  pmid    = {15607954},
  url     = {https://doi.org/10.1016/j.mcn.2004.09.007}
}

@article{chiesa2005-15618403,
  author  = {Chiesa, R. and Piccardo, P. and Dossena, S. and Nowoslawski, L. and Roth, K. A. and Ghetti, B. and Harris, D. A.},
  title   = {{Bax deletion prevents neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2005},
  doi     = {10.1073/pnas.0406173102},
  pmid    = {15618403},
  url     = {https://doi.org/10.1073/pnas.0406173102}
}

@article{he2005-15615712,
  author  = {He, X. and Li, F. and Chang, W. P. and Tang, J.},
  title   = {{GGA proteins mediate the recycling pathway of memapsin 2 (BACE)}},
  journal = {The Journal of biological chemistry},
  year    = {2005},
  doi     = {10.1074/jbc.m411296200},
  pmid    = {15615712},
  url     = {https://doi.org/10.1074/jbc.m411296200}
}

@article{wilcock2004-15588287,
  author  = {Wilcock, D. M. and Rojiani, A. and Rosenthal, A. and Subbarao, S. and Freeman, M. J. and Gordon, M. N. and Morgan, D.},
  title   = {{Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage}},
  journal = {Journal of neuroinflammation},
  year    = {2004},
  doi     = {10.1186/1742-2094-1-24},
  pmid    = {15588287},
  url     = {https://doi.org/10.1186/1742-2094-1-24}
}

@article{trommer2004-15570172,
  author  = {Trommer, B. L. and Shah, C. and Yun, S. H. and Gamkrelidze, G. and Pasternak, E. S. and Ye, G. L. and Sotak, M. and Sullivan, P. M. and others},
  title   = {{ApoE isoform affects LTP in human targeted replacement mice}},
  journal = {Neuroreport},
  year    = {2004},
  doi     = {10.1097/00001756-200412030-00020},
  pmid    = {15570172},
  url     = {https://doi.org/10.1097/00001756-200412030-00020}
}

@article{roumier2004-15601948,
  author  = {Roumier, A. and Béchade, C. and Poncer, J. C. and Smalla, K. H. and Tomasello, E. and Vivier, E. and Gundelfinger, E. D. and Triller, A. and others},
  title   = {{Impaired synaptic function in the microglial KARAP/DAP12-deficient mouse}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2004},
  doi     = {10.1523/jneurosci.2251-04.2004},
  pmid    = {15601948},
  url     = {https://doi.org/10.1523/jneurosci.2251-04.2004}
}

@article{vanmarle2004-15518810,
  author  = {van Marle, G. and Henry, S. and Todoruk, T. and Sullivan, A. and Silva, C. and Rourke, S. B. and Holden, J. and McArthur, J. C. and others},
  title   = {{Human immunodeficiency virus type 1 Nef protein mediates neural cell death: a neurotoxic role for IP-10}},
  journal = {Virology},
  year    = {2004},
  doi     = {10.1016/j.virol.2004.08.024},
  pmid    = {15518810},
  url     = {https://doi.org/10.1016/j.virol.2004.08.024}
}

@article{zhao2004-15485850,
  author  = {Zhao, G. and Mao, G. and Tan, J. and Dong, Y. and Cui, M. Z. and Kim, S. H. and Xu, X.},
  title   = {{Identification of a new presenilin-dependent zeta-cleavage site within the transmembrane domain of amyloid precursor protein}},
  journal = {The Journal of biological chemistry},
  year    = {2004},
  doi     = {10.1074/jbc.c400473200},
  pmid    = {15485850},
  url     = {https://doi.org/10.1074/jbc.c400473200}
}

@article{counts2004-15455399,
  author  = {Counts, S. E. and Nadeem, M. and Wuu, J. and Ginsberg, S. D. and Saragovi, H. U. and Mufson, E. J.},
  title   = {{Reduction of cortical TrkA but not p75(NTR) protein in early-stage Alzheimer's disease}},
  journal = {Annals of neurology},
  year    = {2004},
  doi     = {10.1002/ana.20233},
  pmid    = {15455399},
  url     = {https://doi.org/10.1002/ana.20233}
}

@article{hatakeyama2004-15447663,
  author  = {Hatakeyama, S. and Matsumoto, M. and Kamura, T. and Murayama, M. and Chui, D. H. and Planel, E. and Takahashi, R. and Nakayama, K. I. and others},
  title   = {{U-box protein carboxyl terminus of Hsc70-interacting protein (CHIP) mediates poly-ubiquitylation preferentially on four-repeat Tau and is involved in neurodegeneration of tauopathy}},
  journal = {Journal of neurochemistry},
  year    = {2004},
  doi     = {10.1111/j.1471-4159.2004.02713.x},
  pmid    = {15447663},
  url     = {https://doi.org/10.1111/j.1471-4159.2004.02713.x}
}

@article{deane2004-15459432,
  author  = {Deane, R. and Wu, Z. and Zlokovic, B. V.},
  title   = {{RAGE (yin) versus LRP (yang) balance regulates alzheimer amyloid beta-peptide clearance through transport across the blood-brain barrier}},
  journal = {Stroke},
  year    = {2004},
  doi     = {10.1161/01.str.0000143452.85382.d1},
  pmid    = {15459432},
  url     = {https://doi.org/10.1161/01.str.0000143452.85382.d1}
}

@article{minghetti2004-15453089,
  author  = {Minghetti, L.},
  title   = {{Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases}},
  journal = {Journal of neuropathology and experimental neurology},
  year    = {2004},
  doi     = {10.1093/jnen/63.9.901},
  pmid    = {15453089},
  url     = {https://doi.org/10.1093/jnen/63.9.901}
}

@article{herzig2004-15311281,
  author  = {Herzig, M. C. and Winkler, D. T. and Burgermeister, P. and Pfeifer, M. and Kohler, E. and Schmidt, S. D. and Danner, S. and Abramowski, D. and others},
  title   = {{Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis}},
  journal = {Nature neuroscience},
  year    = {2004},
  doi     = {10.1038/nn1302},
  pmid    = {15311281},
  url     = {https://doi.org/10.1038/nn1302}
}

@article{postina2004-15146243,
  author  = {Postina, R. and Schroeder, A. and Dewachter, I. and Bohl, J. and Schmitt, U. and Kojro, E. and Prinzen, C. and Endres, K. and others},
  title   = {{A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model}},
  journal = {The Journal of clinical investigation},
  year    = {2004},
  doi     = {10.1172/jci20864},
  pmid    = {15146243},
  url     = {https://doi.org/10.1172/jci20864}
}

@article{chung2004-15105460,
  author  = {Chung, K. K. and Thomas, B. and Li, X. and Pletnikova, O. and Troncoso, J. C. and Marsh, L. and Dawson, V. L. and Dawson, T. M.},
  title   = {{S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function}},
  journal = {Science (New York, N.Y.)},
  year    = {2004},
  doi     = {10.1126/science.1093891},
  pmid    = {15105460},
  url     = {https://doi.org/10.1126/science.1093891}
}

@article{wu2004-15285800,
  author  = {Wu, S. Z. and Bodles, A. M. and Porter, M. M. and Griffin, W. S. and Basile, A. S. and Barger, S. W.},
  title   = {{Induction of serine racemase expression and D-serine release from microglia by amyloid beta-peptide}},
  journal = {Journal of neuroinflammation},
  year    = {2004},
  doi     = {10.1186/1742-2094-1-2},
  pmid    = {15285800},
  url     = {https://doi.org/10.1186/1742-2094-1-2}
}

@article{saito2004-15099022,
  author  = {Saito, Y. and Suzuki, K. and Hulette, C. M. and Murayama, S.},
  title   = {{Aberrant phosphorylation of alpha-synuclein in human Niemann-Pick type C1 disease}},
  journal = {Journal of neuropathology and experimental neurology},
  year    = {2004},
  doi     = {10.1093/jnen/63.4.323},
  pmid    = {15099022},
  url     = {https://doi.org/10.1093/jnen/63.4.323}
}

@article{watts2004-15034582,
  author  = {Watts, G. D. and Wymer, J. and Kovach, M. J. and Mehta, S. G. and Mumm, S. and Darvish, D. and Pestronk, A. and Whyte, M. P. and others},
  title   = {{Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein}},
  journal = {Nature genetics},
  year    = {2004},
  doi     = {10.1038/ng1332},
  pmid    = {15034582},
  url     = {https://doi.org/10.1038/ng1332}
}

@article{mizuno2004-14975696,
  author  = {Mizuno, T. and Kurotani, T. and Komatsu, Y. and Kawanokuchi, J. and Kato, H. and Mitsuma, N. and Suzumura, A.},
  title   = {{Neuroprotective role of phosphodiesterase inhibitor ibudilast on neuronal cell death induced by activated microglia}},
  journal = {Neuropharmacology},
  year    = {2004},
  doi     = {10.1016/j.neuropharm.2003.09.009},
  pmid    = {14975696},
  url     = {https://doi.org/10.1016/j.neuropharm.2003.09.009}
}

@article{wen2004-14982935,
  author  = {Wen, Y. and Yang, S. and Liu, R. and Brun-Zinkernagel, A. M. and Koulen, P. and Simpkins, J. W.},
  title   = {{Transient cerebral ischemia induces aberrant neuronal cell cycle re-entry and Alzheimer's disease-like tauopathy in female rats}},
  journal = {The Journal of biological chemistry},
  year    = {2004},
  doi     = {10.1074/jbc.m311768200},
  pmid    = {14982935},
  url     = {https://doi.org/10.1074/jbc.m311768200}
}

@article{lee2004-14985429,
  author  = {Lee, H. J. and Khoshaghideh, F. and Patel, S. and Lee, S. J.},
  title   = {{Clearance of alpha-synuclein oligomeric intermediates via the lysosomal degradation pathway}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2004},
  doi     = {10.1523/jneurosci.3809-03.2004},
  pmid    = {14985429},
  url     = {https://doi.org/10.1523/jneurosci.3809-03.2004}
}

@article{wong2004-14709552,
  author  = {Wong, G. T. and Manfra, D. and Poulet, F. M. and Zhang, Q. and Josien, H. and Bara, T. and Engstrom, L. and Pinzon-Ortiz, M. and others},
  title   = {{Chronic treatment with the gamma-secretase inhibitor LY-411,575 inhibits beta-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation}},
  journal = {The Journal of biological chemistry},
  year    = {2004},
  doi     = {10.1074/jbc.m311652200},
  pmid    = {14709552},
  url     = {https://doi.org/10.1074/jbc.m311652200}
}

@article{dong2004-15283960,
  author  = {Dong, H. and Goico, B. and Martin, M. and Csernansky, C. A. and Bertchume, A. and Csernansky, J. G.},
  title   = {{Modulation of hippocampal cell proliferation, memory, and amyloid plaque deposition in APPsw (Tg2576) mutant mice by isolation stress}},
  journal = {Neuroscience},
  year    = {2004},
  doi     = {10.1016/j.neuroscience.2004.05.040},
  pmid    = {15283960},
  url     = {https://doi.org/10.1016/j.neuroscience.2004.05.040}
}

@article{humphrey2004-14969392,
  author  = {Humphrey, M. B. and Ogasawara, K. and Yao, W. and Spusta, S. C. and Daws, M. R. and Lane, N. E. and Lanier, L. L. and Nakamura, M. C.},
  title   = {{The signaling adapter protein DAP12 regulates multinucleation during osteoclast development}},
  journal = {Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year    = {2004},
  doi     = {10.1359/jbmr.0301234},
  pmid    = {14969392},
  url     = {https://doi.org/10.1359/jbmr.0301234}
}

@article{tanaka2004-14627698,
  author  = {Tanaka, M. and Kim, Y. M. and Lee, G. and Junn, E. and Iwatsubo, T. and Mouradian, M. M.},
  title   = {{Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective}},
  journal = {The Journal of biological chemistry},
  year    = {2004},
  doi     = {10.1074/jbc.m310994200},
  pmid    = {14627698},
  url     = {https://doi.org/10.1074/jbc.m310994200}
}

@article{cox2003-14612559,
  author  = {Cox, P. A. and Banack, S. A. and Murch, S. J.},
  title   = {{Biomagnification of cyanobacterial neurotoxins and neurodegenerative disease among the Chamorro people of Guam}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2003},
  doi     = {10.1073/pnas.2235808100},
  pmid    = {14612559},
  url     = {https://doi.org/10.1073/pnas.2235808100}
}

@article{gorry2003-15049431,
  author  = {Gorry, P. R. and Ong, C. and Thorpe, J. and Bannwarth, S. and Thompson, K. A. and Gatignol, A. and Vesselingh, S. L. and Purcell, D. F.},
  title   = {{Astrocyte infection by HIV-1: mechanisms of restricted virus replication, and role in the pathogenesis of HIV-1-associated dementia}},
  journal = {Current HIV research},
  year    = {2003},
  doi     = {10.2174/1570162033485122},
  pmid    = {15049431},
  url     = {https://doi.org/10.2174/1570162033485122}
}

@article{schlueter2003-14580673,
  author  = {Schlueter, C. and Hauke, S. and Flohr, A. M. and Rogalla, P. and Bullerdiek, J.},
  title   = {{Tissue-specific expression patterns of the RAGE receptor and its soluble forms--a result of regulated alternative splicing?}},
  journal = {Biochimica et biophysica acta},
  year    = {2003},
  doi     = {10.1016/j.bbaexp.2003.08.008},
  pmid    = {14580673},
  url     = {https://doi.org/10.1016/j.bbaexp.2003.08.008}
}

@article{brucekeller2003-12968004,
  author  = {Bruce-Keller, A. J. and Chauhan, A. and Dimayuga, F. O. and Gee, J. and Keller, J. N. and Nath, A.},
  title   = {{Synaptic transport of human immunodeficiency virus-Tat protein causes neurotoxicity and gliosis in rat brain}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2003},
  doi     = {10.1523/jneurosci.23-23-08417.2003},
  pmid    = {12968004},
  url     = {https://doi.org/10.1523/jneurosci.23-23-08417.2003}
}

@article{kinoshita2003-12888553,
  author  = {Kinoshita, A. and Shah, T. and Tangredi, M. M. and Strickland, D. K. and Hyman, B. T.},
  title   = {{The intracellular domain of the low density lipoprotein receptor-related protein modulates transactivation mediated by amyloid precursor protein and Fe65}},
  journal = {The Journal of biological chemistry},
  year    = {2003},
  doi     = {10.1074/jbc.m306403200},
  pmid    = {12888553},
  url     = {https://doi.org/10.1074/jbc.m306403200}
}

@article{deane2003-12808450,
  author  = {Deane, R. and Du Yan, S. and Submamaryan, R. K. and LaRue, B. and Jovanovic, S. and Hogg, E. and Welch, D. and Manness, L. and others},
  title   = {{RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain}},
  journal = {Nature medicine},
  year    = {2003},
  doi     = {10.1038/nm890},
  pmid    = {12808450},
  url     = {https://doi.org/10.1038/nm890}
}

@article{sabo2003-12843239,
  author  = {Sabo, S. L. and Ikin, A. F. and Buxbaum, J. D. and Greengard, P.},
  title   = {{The amyloid precursor protein and its regulatory protein, FE65, in growth cones and synapses in vitro and in vivo}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2003},
  doi     = {10.1523/jneurosci.23-13-05407.2003},
  pmid    = {12843239},
  url     = {https://doi.org/10.1523/jneurosci.23-13-05407.2003}
}

@article{lee2003-12655043,
  author  = {Lee, J. and Ryu, H. and Ferrante, R. J. and Morris, S. M. and Ratan, R. R.},
  title   = {{Translational control of inducible nitric oxide synthase expression by arginine can explain the arginine paradox}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2003},
  doi     = {10.1073/pnas.0735876100},
  pmid    = {12655043},
  url     = {https://doi.org/10.1073/pnas.0735876100}
}

@article{farris2003-12634421,
  author  = {Farris, Wesley and Mansourian, Stefan and Chang, Yang and Lindsley, Loren D. and Eckman, Elizabeth A. and Frosch, Matthew P. and Eckman, Christopher B. and Tanzi, Rudolph E. and Selkoe, Dennis J. and Guénette, Suzanne Y.},
  title   = {{Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain in vivo}},
  journal = {Proceedings of the National Academy of Sciences},
  year    = {2003},
  doi     = {10.1073/pnas.0230450100},
  pmid    = {12634421},
  url     = {https://doi.org/10.1073/pnas.0230450100}
}

@article{wysscoray2003-12612547,
  author  = {Wyss‐Coray, Tony and Loike, John D. and Brionne, Thomas C. and Lu, Emily and Anankov, Roman and Yan, Fengrong and Silverstein, Samuel C. and Husemann, Jens},
  title   = {{Adult mouse astrocytes degrade amyloid-β in vitro and in situ}},
  journal = {Nature Medicine},
  year    = {2003},
  doi     = {10.1038/nm838},
  pmid    = {12612547},
  url     = {https://doi.org/10.1038/nm838}
}

@article{li2003-12629164,
  author  = {Li, Y. and Liu, L. and Barger, S. W. and Griffin, W. S.},
  title   = {{Interleukin-1 mediates pathological effects of microglia on tau phosphorylation and on synaptophysin synthesis in cortical neurons through a p38-MAPK pathway}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2003},
  doi     = {10.1523/jneurosci.23-05-01605.2003},
  pmid    = {12629164},
  url     = {https://doi.org/10.1523/jneurosci.23-05-01605.2003}
}

@article{guillemin2003-12555204,
  author  = {Guillemin, G. J. and Croitoru-Lamoury, J. and Dormont, D. and Armati, P. J. and Brew, B. J.},
  title   = {{Quinolinic acid upregulates chemokine production and chemokine receptor expression in astrocytes}},
  journal = {Glia},
  year    = {2003},
  doi     = {10.1002/glia.10175},
  pmid    = {12555204},
  url     = {https://doi.org/10.1002/glia.10175}
}

@article{su2003-12578975,
  author  = {Su, Z. Z. and Leszczyniecka, M. and Kang, D. C. and Sarkar, D. and Chao, W. and Volsky, D. J. and Fisher, P. B.},
  title   = {{Insights into glutamate transport regulation in human astrocytes: cloning of the promoter for excitatory amino acid transporter 2 (EAAT2)}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2003},
  doi     = {10.1073/pnas.0136555100},
  pmid    = {12578975},
  url     = {https://doi.org/10.1073/pnas.0136555100}
}

@article{chauhan2003-12551932,
  author  = {Chauhan, A. and Turchan, J. and Pocernich, C. and Bruce-Keller, A. and Roth, S. and Butterfield, D. A. and Major, E. O. and Nath, A.},
  title   = {{Intracellular human immunodeficiency virus Tat expression in astrocytes promotes astrocyte survival but induces potent neurotoxicity at distant sites via axonal transport}},
  journal = {The Journal of biological chemistry},
  year    = {2003},
  doi     = {10.1074/jbc.m209381200},
  pmid    = {12551932},
  url     = {https://doi.org/10.1074/jbc.m209381200}
}

@article{chaudhury2003-12528817,
  author  = {Chaudhury, A. R. and Gerecke, K. M. and Wyss, J. M. and Morgan, D. G. and Gordon, M. N. and Carroll, S. L.},
  title   = {{Neuregulin-1 and erbB4 immunoreactivity is associated with neuritic plaques in Alzheimer disease brain and in a transgenic model of Alzheimer disease}},
  journal = {Journal of neuropathology and experimental neurology},
  year    = {2003},
  doi     = {10.1093/jnen/62.1.42},
  pmid    = {12528817},
  url     = {https://doi.org/10.1093/jnen/62.1.42}
}

@article{tschape2002-12456644,
  author  = {Tschäpe, J. A. and Hammerschmied, C. and Mühlig-Versen, M. and Athenstaedt, K. and Daum, G. and Kretzschmar, D.},
  title   = {{The neurodegeneration mutant löchrig interferes with cholesterol homeostasis and Appl processing}},
  journal = {The EMBO journal},
  year    = {2002},
  doi     = {10.1093/emboj/cdf636},
  pmid    = {12456644},
  url     = {https://doi.org/10.1093/emboj/cdf636}
}

@article{banisadr2002-12431218,
  author  = {Banisadr, G. and Fontanges, P. and Haour, F. and Kitabgi, P. and Rostène, W. and Mélik Parsadaniantz, S.},
  title   = {{Neuroanatomical distribution of CXCR4 in adult rat brain and its localization in cholinergic and dopaminergic neurons}},
  journal = {The European journal of neuroscience},
  year    = {2002},
  doi     = {10.1046/j.1460-9568.2002.02237.x},
  pmid    = {12431218},
  url     = {https://doi.org/10.1046/j.1460-9568.2002.02237.x}
}

@article{cosenza2002-12408230,
  author  = {Cosenza, M. A. and Zhao, M. L. and Si, Q. and Lee, S. C.},
  title   = {{Human brain parenchymal microglia express CD14 and CD45 and are productively infected by HIV-1 in HIV-1 encephalitis}},
  journal = {Brain pathology (Zurich, Switzerland)},
  year    = {2002},
  doi     = {10.1111/j.1750-3639.2002.tb00461.x},
  pmid    = {12408230},
  url     = {https://doi.org/10.1111/j.1750-3639.2002.tb00461.x}
}

@article{apelt2002-12384234,
  author  = {Apelt, J. and Kumar, A. and Schliebs, R.},
  title   = {{Impairment of cholinergic neurotransmission in adult and aged transgenic Tg2576 mouse brain expressing the Swedish mutation of human beta-amyloid precursor protein}},
  journal = {Brain research},
  year    = {2002},
  doi     = {10.1016/s0006-8993(02)03262-6},
  pmid    = {12384234},
  url     = {https://doi.org/10.1016/s0006-8993(02)03262-6}
}

@article{minagar2002-12220687,
  author  = {Minagar, A. and Shapshak, P. and Fujimura, R. and Ownby, R. and Heyes, M. and Eisdorfer, C.},
  title   = {{The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis}},
  journal = {Journal of the neurological sciences},
  year    = {2002},
  doi     = {10.1016/s0022-510x(02)00207-1},
  pmid    = {12220687},
  url     = {https://doi.org/10.1016/s0022-510x(02)00207-1}
}

@article{klunk2002-12230326,
  author  = {Klunk, W. E. and Bacskai, B. J. and Mathis, C. A. and Kajdasz, S. T. and McLellan, M. E. and Frosch, M. P. and Debnath, M. L. and Holt, D. P. and others},
  title   = {{Imaging Abeta plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative}},
  journal = {Journal of neuropathology and experimental neurology},
  year    = {2002},
  doi     = {10.1093/jnen/61.9.797},
  pmid    = {12230326},
  url     = {https://doi.org/10.1093/jnen/61.9.797}
}

@article{weeber2002-12167620,
  author  = {Weeber, E. J. and Beffert, U. and Jones, C. and Christian, J. M. and Forster, E. and Sweatt, J. D. and Herz, J.},
  title   = {{Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning}},
  journal = {The Journal of biological chemistry},
  year    = {2002},
  doi     = {10.1074/jbc.m205147200},
  pmid    = {12167620},
  url     = {https://doi.org/10.1074/jbc.m205147200}
}

@article{fiscus2002-12393944,
  author  = {Fiscus, R. R.},
  title   = {{Involvement of cyclic GMP and protein kinase G in the regulation of apoptosis and survival in neural cells}},
  journal = {Neuro-Signals},
  year    = {2002},
  doi     = {10.1159/000065431},
  pmid    = {12393944},
  url     = {https://doi.org/10.1159/000065431}
}

@article{rockenstein2002-12111846,
  author  = {Rockenstein, E. and Mallory, M. and Hashimoto, M. and Song, D. and Shults, C. W. and Lang, I. and Masliah, E.},
  title   = {{Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters}},
  journal = {Journal of neuroscience research},
  year    = {2002},
  doi     = {10.1002/jnr.10231},
  pmid    = {12111846},
  url     = {https://doi.org/10.1002/jnr.10231}
}

@article{ermak2002-12039863,
  author  = {Ermak, G. and Harris, C. D. and Davies, K. J.},
  title   = {{The DSCR1 (Adapt78) isoform 1 protein calcipressin 1 inhibits calcineurin and protects against acute calcium-mediated stress damage, including transient oxidative stress}},
  journal = {FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year    = {2002},
  doi     = {10.1096/fj.01-0846com},
  pmid    = {12039863},
  url     = {https://doi.org/10.1096/fj.01-0846com}
}

@article{su2002-12032861,
  author  = {Su, Z. Z. and Kang, D. C. and Chen, Y. and Pekarskaya, O. and Chao, W. and Volsky, D. J. and Fisher, P. B.},
  title   = {{Identification and cloning of human astrocyte genes displaying elevated expression after infection with HIV-1 or exposure to HIV-1 envelope glycoprotein by rapid subtraction hybridization, RaSH}},
  journal = {Oncogene},
  year    = {2002},
  doi     = {10.1038/sj.onc.1205445},
  pmid    = {12032861},
  url     = {https://doi.org/10.1038/sj.onc.1205445}
}

@article{liu2002-12076984,
  author  = {Liu, B. and Gao, H. M. and Wang, J. Y. and Jeohn, G. H. and Cooper, C. L. and Hong, J. S.},
  title   = {{Role of nitric oxide in inflammation-mediated neurodegeneration}},
  journal = {Annals of the New York Academy of Sciences},
  year    = {2002},
  doi     = {10.1111/j.1749-6632.2002.tb04077.x},
  pmid    = {12076984},
  url     = {https://doi.org/10.1111/j.1749-6632.2002.tb04077.x}
}

@article{walsh2002-11932745,
  author  = {Walsh, Dominic M. and Klyubin, Igor V. and Fadeeva, Julia V. and Cullen, William K. and Anwyl, Roger and Wolfe, Michael S. and Rowan, Michael J. and Selkoe, Dennis J.},
  title   = {{Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo}},
  journal = {Nature},
  year    = {2002},
  doi     = {10.1038/416535a},
  pmid    = {11932745},
  url     = {https://doi.org/10.1038/416535a}
}

@article{jantzen2002-11896164,
  author  = {Jantzen, P. T. and Connor, K. E. and DiCarlo, G. and Wenk, G. L. and Wallace, J. L. and Rojiani, A. M. and Coppola, D. and Morgan, D. and others},
  title   = {{Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2002},
  doi     = {10.1523/jneurosci.22-06-02246.2002},
  pmid    = {11896164},
  url     = {https://doi.org/10.1523/jneurosci.22-06-02246.2002}
}

@article{vanderhart2002-12399945,
  author  = {van der Hart, M. G. and Czéh, B. and de Biurrun, G. and Michaelis, T. and Watanabe, T. and Natt, O. and Frahm, J. and Fuchs, E.},
  title   = {{Substance P receptor antagonist and clomipramine prevent stress-induced alterations in cerebral metabolites, cytogenesis in the dentate gyrus and hippocampal volume}},
  journal = {Molecular psychiatry},
  year    = {2002},
  doi     = {10.1038/sj.mp.4001130},
  pmid    = {12399945},
  url     = {https://doi.org/10.1038/sj.mp.4001130}
}

@article{fischersmith2001-11704885,
  author  = {Fischer-Smith, T. and Croul, S. and Sverstiuk, A. E. and Capini, C. and L'Heureux, D. and Régulier, E. G. and Richardson, M. W. and Amini, S. and others},
  title   = {{CNS invasion by CD14+/CD16+ peripheral blood-derived monocytes in HIV dementia: perivascular accumulation and reservoir of HIV infection}},
  journal = {Journal of neurovirology},
  year    = {2001},
  doi     = {10.1080/135502801753248114},
  pmid    = {11704885},
  url     = {https://doi.org/10.1080/135502801753248114}
}

@article{youdim2001-12043833,
  author  = {Youdim, M. B. and Weinstock, M.},
  title   = {{Molecular basis of neuroprotective activities of rasagiline and the anti-Alzheimer drug TV3326 [(N-propargyl-(3R)aminoindan-5-YL)-ethyl methyl carbamate]}},
  journal = {Cellular and molecular neurobiology},
  year    = {2001},
  doi     = {10.1023/a:1015131516649},
  pmid    = {12043833},
  url     = {https://doi.org/10.1023/a:1015131516649}
}

@article{gorry2001-11581376,
  author  = {Gorry, P. R. and Bristol, G. and Zack, J. A. and Ritola, K. and Swanstrom, R. and Birch, C. J. and Bell, J. E. and Bannert, N. and others},
  title   = {{Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity}},
  journal = {Journal of virology},
  year    = {2001},
  doi     = {10.1128/jvi.75.21.10073-10089.2001},
  pmid    = {11581376},
  url     = {https://doi.org/10.1128/jvi.75.21.10073-10089.2001}
}

@article{lim2001-11606625,
  author  = {Lim, G. P. and Chu, T. and Yang, F. and Beech, W. and Frautschy, S. A. and Cole, G. M.},
  title   = {{The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2001},
  doi     = {10.1523/jneurosci.21-21-08370.2001},
  pmid    = {11606625},
  url     = {https://doi.org/10.1523/jneurosci.21-21-08370.2001}
}

@article{bouchon2001-11602640,
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  title   = {{A DAP12-mediated pathway regulates expression of CC chemokine receptor 7 and maturation of human dendritic cells}},
  journal = {The Journal of experimental medicine},
  year    = {2001},
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  pmid    = {11602640},
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}

@article{rosso2001-11571213,
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  title   = {{Familial frontotemporal dementia with ubiquitin-positive inclusions is linked to chromosome 17q21-22}},
  journal = {Brain : a journal of neurology},
  year    = {2001},
  doi     = {10.1093/brain/124.10.1948},
  pmid    = {11571213},
  url     = {https://doi.org/10.1093/brain/124.10.1948}
}

@article{chung2001-11590439,
  author  = {Chung, K. K. and Zhang, Y. and Lim, K. L. and Tanaka, Y. and Huang, H. and Gao, J. and Ross, C. A. and Dawson, V. L. and others},
  title   = {{Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease}},
  journal = {Nature medicine},
  year    = {2001},
  doi     = {10.1038/nm1001-1144},
  pmid    = {11590439},
  url     = {https://doi.org/10.1038/nm1001-1144}
}

@article{masliah2001-11572944,
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  title   = {{beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2001},
  doi     = {10.1073/pnas.211412398},
  pmid    = {11572944},
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}

@article{heneka2001-11556547,
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  title   = {{Neuronal and glial coexpression of argininosuccinate synthetase and inducible nitric oxide synthase in Alzheimer disease}},
  journal = {Journal of neuropathology and experimental neurology},
  year    = {2001},
  doi     = {10.1093/jnen/60.9.906},
  pmid    = {11556547},
  url     = {https://doi.org/10.1093/jnen/60.9.906}
}

@article{gotz2001-11520988,
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  title   = {{Formation of Neurofibrillary Tangles in P301L Tau Transgenic Mice Induced by Aβ42 Fibrils}},
  journal = {Science},
  year    = {2001},
  doi     = {10.1126/science.1062097},
  pmid    = {11520988},
  url     = {https://doi.org/10.1126/science.1062097}
}

@article{guillemin2001-11520905,
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  title   = {{Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection}},
  journal = {Journal of neurochemistry},
  year    = {2001},
  doi     = {10.1046/j.1471-4159.2001.00498.x},
  pmid    = {11520905},
  url     = {https://doi.org/10.1046/j.1471-4159.2001.00498.x}
}

@article{volles2001-11425308,
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  title   = {{Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease}},
  journal = {Biochemistry},
  year    = {2001},
  doi     = {10.1021/bi0102398},
  pmid    = {11425308},
  url     = {https://doi.org/10.1021/bi0102398}
}

@article{schuller2001-11441917,
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  title   = {{Brain t-complex polypeptide 1 (TCP- 1) related to its natural substrate beta1 tubulin is decreased in Alzheimer's disease}},
  journal = {Life sciences},
  year    = {2001},
  doi     = {10.1016/s0024-3205(01)01126-2},
  pmid    = {11441917},
  url     = {https://doi.org/10.1016/s0024-3205(01)01126-2}
}

@article{krugel2001-11337195,
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  title   = {{Deafferentation of the septo-hippocampal pathway in rats as a model of the metabolic events in Alzheimer's disease}},
  journal = {International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience},
  year    = {2001},
  doi     = {10.1016/s0736-5748(01)00010-7},
  pmid    = {11337195},
  url     = {https://doi.org/10.1016/s0736-5748(01)00010-7}
}

@article{wysscoray2001-11329064,
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  title   = {{TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice}},
  journal = {Nature medicine},
  year    = {2001},
  doi     = {10.1038/87945},
  pmid    = {11329064},
  url     = {https://doi.org/10.1038/87945}
}

@article{gurwell2001-11226693,
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  title   = {{Synergistic neurotoxicity of opioids and human immunodeficiency virus-1 Tat protein in striatal neurons in vitro}},
  journal = {Neuroscience},
  year    = {2001},
  doi     = {10.1016/s0306-4522(00)00461-9},
  pmid    = {11226693},
  url     = {https://doi.org/10.1016/s0306-4522(00)00461-9}
}

@article{takeuchi2000-11138929,
  author  = {Takeuchi, M. and Bucala, R. and Suzuki, T. and Ohkubo, T. and Yamazaki, M. and Koike, T. and Kameda, Y. and Makita, Z.},
  title   = {{Neurotoxicity of advanced glycation end-products for cultured cortical neurons}},
  journal = {Journal of neuropathology and experimental neurology},
  year    = {2000},
  doi     = {10.1093/jnen/59.12.1094},
  pmid    = {11138929},
  url     = {https://doi.org/10.1093/jnen/59.12.1094}
}

@article{mufson2000-11042589,
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  title   = {{Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease}},
  journal = {The Journal of comparative neurology},
  year    = {2000},
  doi     = {10.1002/1096-9861(20001106)427:1<19::aid-cne2>3.0.co;2-a},
  pmid    = {11042589},
  url     = {https://doi.org/10.1002/1096-9861(20001106)427:1<19::aid-cne2>3.0.co;2-a}
}

@article{tulliopelet2000-11062474,
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  title   = {{Mutant WD-repeat protein in triple-A syndrome}},
  journal = {Nature genetics},
  year    = {2000},
  doi     = {10.1038/81642},
  pmid    = {11062474},
  url     = {https://doi.org/10.1038/81642}
}

@article{giasson2000-11062131,
  author  = {Giasson, B. I. and Duda, J. E. and Murray, IV. and Chen, Q. and Souza, J. M. and Hurtig, H. I. and Ischiropoulos, H. and Trojanowski, J. Q. and others},
  title   = {{Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions}},
  journal = {Science (New York, N.Y.)},
  year    = {2000},
  doi     = {10.1126/science.290.5493.985},
  pmid    = {11062131},
  url     = {https://doi.org/10.1126/science.290.5493.985}
}

@article{stone2000-10964484,
  author  = {Stone, D. J. and Rozovsky, I. and Morgan, T. E. and Anderson, C. P. and Lopez, L. M. and Shick, J. and Finch, C. E.},
  title   = {{Effects of age on gene expression during estrogen-induced synaptic sprouting in the female rat}},
  journal = {Experimental neurology},
  year    = {2000},
  doi     = {10.1006/exnr.2000.7455},
  pmid    = {10964484},
  url     = {https://doi.org/10.1006/exnr.2000.7455}
}

@article{lewis2000-10932182,
  author  = {Lewis, J. and McGowan, E. and Rockwood, J. and Melrose, H. and Nacharaju, P. and Van Slegtenhorst, M. and Gwinn-Hardy, K. and Paul Murphy, M. and others},
  title   = {{Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein}},
  journal = {Nature genetics},
  year    = {2000},
  doi     = {10.1038/78078},
  pmid    = {10932182},
  url     = {https://doi.org/10.1038/78078}
}

@article{ostrerovagolts2000-10934254,
  author  = {Ostrerova-Golts, N. and Petrucelli, L. and Hardy, J. and Lee, J. M. and Farer, M. and Wolozin, B.},
  title   = {{The A53T alpha-synuclein mutation increases iron-dependent aggregation and toxicity}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2000},
  doi     = {10.1523/jneurosci.20-16-06048.2000},
  pmid    = {10934254},
  url     = {https://doi.org/10.1523/jneurosci.20-16-06048.2000}
}

@article{paloneva2000-10888890,
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  title   = {{Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts}},
  journal = {Nature genetics},
  year    = {2000},
  doi     = {10.1038/77153},
  pmid    = {10888890},
  url     = {https://doi.org/10.1038/77153}
}

@article{mucke2000-10818140,
  author  = {Mucke, Lennart and Masliah, Eliezer and Yu, Gui-Qiu and Mallory, Margaret E. and Rockenstein, Edward M. and Tatsuno, Gwen P. and Hu, Kang and Kholodenko, Dora and Johnson‐Wood, Kelly and McConlogue, Lisa},
  title   = {{High-Level Neuronal Expression of Aβ1–42in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation}},
  journal = {Journal of Neuroscience},
  year    = {2000},
  doi     = {10.1523/jneurosci.20-11-04050.2000},
  pmid    = {10818140},
  url     = {https://doi.org/10.1523/jneurosci.20-11-04050.2000}
}

@article{monzonmayor2000-10821927,
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  title   = {{Long-term evolution of local, proximal and remote astrocyte responses after diverse nucleus basalis lesioning (an experimental Alzheimer model): GFAP immunocytochemical study}},
  journal = {Brain research},
  year    = {2000},
  doi     = {10.1016/s0006-8993(00)02231-9},
  pmid    = {10821927},
  url     = {https://doi.org/10.1016/s0006-8993(00)02231-9}
}

@article{borchardt1999-10567229,
  author  = {Borchardt, T. and Camakaris, J. and Cappai, R. and Masters, C. L. and Beyreuther, K. and Multhaup, G.},
  title   = {{Copper inhibits beta-amyloid production and stimulates the non-amyloidogenic pathway of amyloid-precursor-protein secretion}},
  journal = {The Biochemical journal},
  year    = {1999},
  doi     = {10.1042/bj3440461},
  pmid    = {10567229},
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}

@article{persidsky1999-10550317,
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  title   = {{Microglial and astrocyte chemokines regulate monocyte migration through the blood-brain barrier in human immunodeficiency virus-1 encephalitis}},
  journal = {The American journal of pathology},
  year    = {1999},
  doi     = {10.1016/s0002-9440(10)65476-4},
  pmid    = {10550317},
  url     = {https://doi.org/10.1016/s0002-9440(10)65476-4}
}

@article{schipper1999-12835114,
  author  = {Schipper, H. M.},
  title   = {{Glial HO-1 expression, iron deposition and oxidative stress in neurodegenerative diseases}},
  journal = {Neurotoxicity research},
  year    = {1999},
  doi     = {10.1007/bf03033339},
  pmid    = {12835114},
  url     = {https://doi.org/10.1007/bf03033339}
}

@article{weiss1999-10453044,
  author  = {Weiss, J. M. and Nath, A. and Major, E. O. and Berman, J. W.},
  title   = {{HIV-1 Tat induces monocyte chemoattractant protein-1-mediated monocyte transmigration across a model of the human blood-brain barrier and up-regulates CCR5 expression on human monocytes}},
  journal = {Journal of immunology (Baltimore, Md. : 1950)},
  year    = {1999},
  doi     = {10.4049/jimmunol.163.5.2953},
  pmid    = {10453044},
  url     = {https://doi.org/10.4049/jimmunol.163.5.2953}
}

@article{kaul1999-10393974,
  author  = {Kaul, M. and Lipton, S. A.},
  title   = {{Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {1999},
  doi     = {10.1073/pnas.96.14.8212},
  pmid    = {10393974},
  url     = {https://doi.org/10.1073/pnas.96.14.8212}
}

@article{perry1999-10354606,
  author  = {Perry, E. and Walker, M. and Grace, J. and Perry, R.},
  title   = {{Acetylcholine in mind: a neurotransmitter correlate of consciousness?}},
  journal = {Trends in neurosciences},
  year    = {1999},
  doi     = {10.1016/s0166-2236(98)01361-7},
  pmid    = {10354606},
  url     = {https://doi.org/10.1016/s0166-2236(98)01361-7}
}

@article{wolfe1999-10206644,
  author  = {Wolfe, Michael S. and Xia, Weiming and Ostaszewski, Beth L. and Diehl, Thekla S. and Kimberly, William Taylor and Selkoe, Dennis J.},
  title   = {{Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity}},
  journal = {Nature},
  year    = {1999},
  doi     = {10.1038/19077},
  pmid    = {10206644},
  url     = {https://doi.org/10.1038/19077}
}

@article{schmidt1999-10082470,
  author  = {Schmidt, A. M. and Yan, S. D. and Wautier, J. L. and Stern, D.},
  title   = {{Activation of receptor for advanced glycation end products: a mechanism for chronic vascular dysfunction in diabetic vasculopathy and atherosclerosis}},
  journal = {Circulation research},
  year    = {1999},
  doi     = {10.1161/01.res.84.5.489},
  pmid    = {10082470},
  url     = {https://doi.org/10.1161/01.res.84.5.489}
}

@article{johnstone1999-10378882,
  author  = {Johnstone, M. and Gearing, A. J. and Miller, K. M.},
  title   = {{A central role for astrocytes in the inflammatory response to beta-amyloid; chemokines, cytokines and reactive oxygen species are produced}},
  journal = {Journal of neuroimmunology},
  year    = {1999},
  doi     = {10.1016/s0165-5728(98)00226-4},
  pmid    = {10378882},
  url     = {https://doi.org/10.1016/s0165-5728(98)00226-4}
}

@article{albright1999-9847323,
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  title   = {{Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates}},
  journal = {Journal of virology},
  year    = {1999},
  doi     = {10.1128/jvi.73.1.205-213.1999},
  pmid    = {9847323},
  url     = {https://doi.org/10.1128/jvi.73.1.205-213.1999}
}

@article{schwab1998-9862635,
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  title   = {{Extracellular neurofibrillary tangles are immunopositive for the 40 carboxy-terminal sequence of beta-amyloid protein}},
  journal = {Journal of neuropathology and experimental neurology},
  year    = {1998},
  doi     = {10.1097/00005072-199812000-00004},
  pmid    = {9862635},
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}

@article{jensen1998-9756856,
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  title   = {{Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation}},
  journal = {The Journal of biological chemistry},
  year    = {1998},
  doi     = {10.1074/jbc.273.41.26292},
  pmid    = {9756856},
  url     = {https://doi.org/10.1074/jbc.273.41.26292}
}

@article{haug1998-9761455,
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  title   = {{Intracerebroventricular administration of quinolinic acid induces a selective decrease of inositol(1,4,5)-trisphosphate receptor in rat brain}},
  journal = {Neurochemistry international},
  year    = {1998},
  doi     = {10.1016/s0197-0186(98)00021-7},
  pmid    = {9761455},
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}

@article{yu1998-9632714,
  author  = {Yu, G. and Chen, F. and Levesque, G. and Nishimura, M. and Zhang, D. M. and Levesque, L. and Rogaeva, E. and Xu, D. and others},
  title   = {{The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin}},
  journal = {The Journal of biological chemistry},
  year    = {1998},
  doi     = {10.1074/jbc.273.26.16470},
  pmid    = {9632714},
  url     = {https://doi.org/10.1074/jbc.273.26.16470}
}

@article{simons1998-9600988,
  author  = {Simons, Mikael and Keller, Patrick and De Strooper, Bart and Beyreuther, Konrad T. and Dotti, Carlos G. and Simons, Kai},
  title   = {{Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons}},
  journal = {Proceedings of the National Academy of Sciences},
  year    = {1998},
  doi     = {10.1073/pnas.95.11.6460},
  pmid    = {9600988},
  url     = {https://doi.org/10.1073/pnas.95.11.6460}
}

@article{lambert1998-9600986,
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  title   = {{Diffusible, nonfibrillar ligands derived from Aβ 1–42 are potent central nervous system neurotoxins}},
  journal = {Proceedings of the National Academy of Sciences},
  year    = {1998},
  doi     = {10.1073/pnas.95.11.6448},
  pmid    = {9600986},
  url     = {https://doi.org/10.1073/pnas.95.11.6448}
}

@article{minn1998-9517566,
  author  = {Minn, A. and Schubert, M. and Neiss, W. F. and Müller-Hill, B.},
  title   = {{Enhanced GFAP expression in astrocytes of transgenic mice expressing the human brain-specific trypsinogen IV}},
  journal = {Glia},
  year    = {1998},
  doi     = {10.1002/(sici)1098-1136(199804)22:4<338::aid-glia3>3.0.co;2-#},
  pmid    = {9517566},
  url     = {https://doi.org/10.1002/(sici)1098-1136(199804)22:4<338::aid-glia3>3.0.co;2-#}
}

@article{sheng1998-9542587,
  author  = {Sheng, J. G. and Mrak, R. E. and Griffin, W. S.},
  title   = {{Enlarged and phagocytic, but not primed, interleukin-1 alpha-immunoreactive microglia increase with age in normal human brain}},
  journal = {Acta neuropathologica},
  year    = {1998},
  doi     = {10.1007/s004010050792},
  pmid    = {9542587},
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@article{ermekova1997-9407065,
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  title   = {{The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled}},
  journal = {The Journal of biological chemistry},
  year    = {1997},
  doi     = {10.1074/jbc.272.52.32869},
  pmid    = {9407065},
  url     = {https://doi.org/10.1074/jbc.272.52.32869}
}

@article{lavi1997-9327737,
  author  = {Lavi, E. and Strizki, J. M. and Ulrich, A. M. and Zhang, W. and Fu, L. and Wang, Q. and O'Connor, M. and Hoxie, J. A. and others},
  title   = {{CXCR-4 (Fusin), a co-receptor for the type 1 human immunodeficiency virus (HIV-1), is expressed in the human brain in a variety of cell types, including microglia and neurons}},
  journal = {The American journal of pathology},
  year    = {1997},
  pmid    = {9327737}
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@article{jordan1997-9214529,
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  pmid    = {9214529},
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}

@article{seilhean1997-9144590,
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  title   = {{Tumor necrosis factor-alpha, microglia and astrocytes in AIDS dementia complex}},
  journal = {Acta neuropathologica},
  year    = {1997},
  doi     = {10.1007/s004010050646},
  pmid    = {9144590},
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@article{mcdonald1997-9065490,
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  title   = {{Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {1997},
  doi     = {10.1523/jneurosci.17-07-02284.1997},
  pmid    = {9065490},
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@article{he1997-9024664,
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  title   = {{CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia}},
  journal = {Nature},
  year    = {1997},
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  pmid    = {9024664},
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@article{ostergranite1996-8824314,
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  title   = {{Age-dependent neuronal and synaptic degeneration in mice transgenic for the C terminus of the amyloid precursor protein}},
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  year    = {1996},
  doi     = {10.1523/jneurosci.16-21-06732.1996},
  pmid    = {8824314},
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@article{joutel1996-8878478,
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  title   = {{Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia}},
  journal = {Nature},
  year    = {1996},
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  pmid    = {8878478},
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@article{hsich1996-8782499,
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  title   = {{The 14-3-3 brain protein in cerebrospinal fluid as a marker for transmissible spongiform encephalopathies}},
  journal = {The New England journal of medicine},
  year    = {1996},
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  pmid    = {8782499},
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}

@article{bagasra1996-8780811,
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  title   = {{Cellular reservoirs of HIV-1 in the central nervous system of infected individuals: identification by the combination of in situ polymerase chain reaction and immunohistochemistry}},
  journal = {AIDS (London, England)},
  year    = {1996},
  doi     = {10.1097/00002030-199606000-00002},
  pmid    = {8780811},
  url     = {https://doi.org/10.1097/00002030-199606000-00002}
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@article{fine1996-8663435,
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  title   = {{Tumor necrosis factor alpha inhibits glutamate uptake by primary human astrocytes. Implications for pathogenesis of HIV-1 dementia}},
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@article{ali1996-8737665,
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  title   = {{Induction of apolipoprotein E mRNA in the hippocampus of the gerbil after transient global ischemia}},
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  year    = {1996},
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@article{christie1996-8786409,
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  title   = {{Expression of the very low-density lipoprotein receptor (VLDL-r), an apolipoprotein-E receptor, in the central nervous system and in Alzheimer's disease}},
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  year    = {1996},
  doi     = {10.1097/00005072-199604000-00012},
  pmid    = {8786409},
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@article{tu1996-8610185,
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  title   = {{Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {1996},
  doi     = {10.1073/pnas.93.7.3155},
  pmid    = {8610185},
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@article{james1996-8744404,
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  title   = {{Neurodegenerative changes including altered tau phosphorylation and neurofilament immunoreactivity in mice transgenic for the serine/threonine kinase Mos}},
  journal = {Neurobiology of aging},
  year    = {1996},
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  pmid    = {8744404},
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@article{askanas1996-8577761,
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  title   = {{Transfer of beta-amyloid precursor protein gene using adenovirus vector causes mitochondrial abnormalities in cultured normal human muscle}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {1996},
  doi     = {10.1073/pnas.93.3.1314},
  pmid    = {8577761},
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@article{pasinetti1996-8980020,
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  title   = {{Hereditary deficiencies in complement C5 are associated with intensified neurodegenerative responses that implicate new roles for the C-system in neuronal and astrocytic functions}},
  journal = {Neurobiology of disease},
  year    = {1996},
  doi     = {10.1006/nbdi.1996.0020},
  pmid    = {8980020},
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@article{schmidtmayerova1996-8570619,
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  title   = {{Human immunodeficiency virus type 1 infection alters chemokine beta peptide expression in human monocytes: implications for recruitment of leukocytes into brain and lymph nodes}},
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  year    = {1996},
  doi     = {10.1073/pnas.93.2.700},
  pmid    = {8570619},
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}

@article{yao1995-8846093,
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  title   = {{Chronic elevation of S100 beta protein does not alter APP mRNA expression or promote beta-amyloid deposition in the brains of aging transgenic mice}},
  journal = {Brain research},
  year    = {1995},
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  pmid    = {8846093},
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@article{gitter1995-7479875,
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  title   = {{Amyloid beta peptide potentiates cytokine secretion by interleukin-1 beta-activated human astrocytoma cells}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {1995},
  doi     = {10.1073/pnas.92.23.10738},
  pmid    = {7479875},
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}

@article{holtzman1995-7568158,
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  title   = {{Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line}},
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  year    = {1995},
  doi     = {10.1073/pnas.92.21.9480},
  pmid    = {7568158},
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@article{ranki1995-8527071,
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  title   = {{Abundant expression of HIV Nef and Rev proteins in brain astrocytes in vivo is associated with dementia}},
  journal = {AIDS (London, England)},
  year    = {1995},
  doi     = {10.1097/00002030-199509000-00004},
  pmid    = {8527071},
  url     = {https://doi.org/10.1097/00002030-199509000-00004}
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  title   = {{Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors}},
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  year    = {1995},
  doi     = {10.1073/pnas.92.17.8083},
  pmid    = {7644542},
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@article{giulian1995-7655344,
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  title   = {{Senile plaques stimulate microglia to release a neurotoxin found in Alzheimer brain}},
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  year    = {1995},
  doi     = {10.1016/0197-0186(95)00067-i},
  pmid    = {7655344},
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  title   = {{Loss of synaptophysin-like immunoreactivity in the hippocampal formation is an early phenomenon in Alzheimer's disease}},
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  year    = {1995},
  doi     = {10.1016/0306-4522(94)00422-2},
  pmid    = {7700527},
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  title   = {{Secreted beta-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {1994},
  doi     = {10.1073/pnas.91.15.7104},
  pmid    = {8041753},
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  title   = {{Human neurons derived from a teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular beta-amyloid or A4 peptides}},
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  year    = {1993},
  doi     = {10.1073/pnas.90.20.9513},
  pmid    = {8415732},
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  title   = {{Chloroquine inhibits intracellular degradation but not secretion of Alzheimer beta/A4 amyloid precursor protein}},
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  year    = {1992},
  doi     = {10.1073/pnas.89.6.2252},
  pmid    = {1549591},
  url     = {https://doi.org/10.1073/pnas.89.6.2252}
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  title   = {{Reactive microglia/macrophages phagocytose amyloid precursor protein produced by neurons following neural damage}},
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  year    = {1992},
  doi     = {10.1002/jnr.490310306},
  pmid    = {1640496},
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  pmid    = {2121800},
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  year    = {1990},
  doi     = {10.1097/00005072-199007000-00004},
  pmid    = {2163437},
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  title   = {{Astrocytic pathology of methionine sulfoximine-induced encephalopathy}},
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  year    = {1989},
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  pmid    = {2565645},
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  title   = {{Nerve growth factor increases mRNA levels for the prion protein and the beta-amyloid protein precursor in developing hamster brain}},
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  year    = {1988},
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  pmid    = {2904679},
  url     = {https://doi.org/10.1073/pnas.85.24.9811}
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@article{mcgeer1988-3399080,
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  title   = {{Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains}},
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  year    = {1988},
  doi     = {10.1212/wnl.38.8.1285},
  pmid    = {3399080},
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  year    = {1987},
  doi     = {10.1007/bf02833599},
  pmid    = {3306480},
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@article{kimura1986-3727931,
  author  = {Kimura, T. and Budka, H.},
  title   = {{Glial fibrillary acidic protein and S-100 protein in human hepatic encephalopathy: immunocytochemical demonstration of dissociation of two glia-associated proteins}},
  journal = {Acta neuropathologica},
  year    = {1986},
  doi     = {10.1007/bf00689509},
  pmid    = {3727931},
  url     = {https://doi.org/10.1007/bf00689509}
}