% alzhub.org topic: proteostasis
% Source: https://alzhub.org/topic/proteostasis
% 240 entries, in the order the page lists them. Built from alzhub.org's own records.
% 0 entries have no readable author in the source record and carry no author field.

@article{qureshi2026-118c9caa,
  author  = {Qureshi, Y. H. and Guo, J. and Rinald, J. H. and Li, Z. and Soni, R. K. and Govindarajan, A. and Tortora, E. and Uzunova, G. and others},
  title   = {{Disrupting SORL1-retromer endosomal recycling in mice drives the age-dependent neurodegenerative signature of Alzheimer's disease}},
  journal = {bioRxiv},
  year    = {2026},
  doi     = {10.64898/2026.10.26.761980},
  url     = {https://doi.org/10.64898/2026.10.26.761980}
}

@article{riordan2026-da5e172b,
  author  = {Riordan, R. and Saxton, A. and Han, M. and Parrot, K. and Kraemer, B.},
  title   = {{TMEM106B C-Terminal fragment aggregation exacerbates α-synuclein and TDP-43 proteinopathy phenotypes}},
  journal = {bioRxiv},
  year    = {2026},
  doi     = {10.64898/2026.10.29.762961},
  url     = {https://doi.org/10.64898/2026.10.29.762961}
}

@article{fluegge2026-da7070f6,
  author  = {Fluegge, K.},
  title   = {{The Filamin A Proteomic Switch: Solubility States and Cytoskeletal Dynamics Explain the Inverse Epidemiological Relationship Between Cancer and Alzheimer’s Disease}},
  journal = {Preprints.org},
  year    = {2026},
  doi     = {10.20944/preprints202609.0194.v5},
  url     = {https://doi.org/10.20944/preprints202609.0194.v5}
}

@article{roy2026-9b2290e4,
  author  = {Roy, B. and Contu, V. R. and Jeziorek, M. and Friedman, W. J. and Wong, C.},
  title   = {{TMEM55B downregulation promotes neurodegeneration in Alzheimer’s disease models}},
  journal = {bioRxiv},
  year    = {2026},
  doi     = {10.64898/2026.10.21.760809},
  url     = {https://doi.org/10.64898/2026.10.21.760809}
}

@article{heuer2026-8adbb044,
  author  = {Heuer, S. E. and Ahsan, F. M. and Terzioglu, G. and Misra, A. and Duong, D. and Katkar, C. and Giera, M. and van der Kant, R. and others},
  title   = {{The Alzheimer’s disease risk gene ABCA7 regulates microglial lysosomal and lipid homeostasis and promotes phagocytosis to maintain neuronal health}},
  journal = {bioRxiv},
  year    = {2026},
  doi     = {10.64898/2026.10.16.759681},
  url     = {https://doi.org/10.64898/2026.10.16.759681}
}

@article{bagade2026-5a084b25,
  author  = {Bagade, A. V. and Miller, R. and Dearborn, J. T. and Basore, K. and Summers, B. and Readnour, B. and Koelling, M. and O’Shea, J. and others},
  title   = {{Intrastriatal injection of amplified Lewy body dementia (LBD) fibrils in mice results in accumulation of fibrils with LBD structure and neurodegeneration}},
  journal = {bioRxiv},
  year    = {2026},
  doi     = {10.64898/2026.10.06.757103},
  url     = {https://doi.org/10.64898/2026.10.06.757103}
}

@article{maita2026-e1e796ab,
  author  = {Maita, N. and Kim, S. and Kajino, Y. and Kato, M.},
  title   = {{ALS-associated mutations reveal a conserved C-terminal self-assembly module in the TDP-43 low-complexity domain}},
  journal = {bioRxiv},
  year    = {2026},
  doi     = {10.64898/2026.10.09.756561},
  url     = {https://doi.org/10.64898/2026.10.09.756561}
}

@article{jimenezsanchez2026-0a11e557,
  author  = {Jimenez-Sanchez, M. and Lobo, P. B. and Yang, F. and Power, C. and Böken, D. and Verlin, L. and Guzman-Hernandez, R. and Cantallops-Jimenez, S. and others},
  title   = {{An astrocyte-neuron HSPB1 axis preserves lysosomal integrity and protects from tau pathology}},
  journal = {Research Square},
  year    = {2026},
  doi     = {10.21203/rs.3.rs-11192311/v1},
  url     = {https://doi.org/10.21203/rs.3.rs-11192311/v1}
}

@article{yarlagadda2026-02a60d50,
  author  = {Yarlagadda, B. and Kumar, V.},
  title   = {{Genetically distinct neurodegenerative proteinopathies engage overlapping proteostasis components}},
  journal = {bioRxiv},
  year    = {2026},
  doi     = {10.64898/2026.09.28.753000},
  url     = {https://doi.org/10.64898/2026.09.28.753000}
}

@article{bridges2026-2036feab,
  author  = {Bridges, L. R.},
  title   = {{Repetitive RNA Is Present in Prion-Infected Mouse Brains}},
  journal = {Preprints.org},
  year    = {2026},
  doi     = {10.20944/preprints202610.0105.v1},
  url     = {https://doi.org/10.20944/preprints202610.0105.v1}
}

@article{murthygowda2026-8155c39b,
  author  = {MurthyGowda, S. and Huyghue, K. and Castillo, B. and Gugala, F. and Li, W. and Dubnau, J.},
  title   = {{Early life social isolation primes flies for more rapid TDP-43 dependent neurodegeneration later in life}},
  journal = {bioRxiv},
  year    = {2026},
  doi     = {10.64898/2026.09.23.753732},
  url     = {https://doi.org/10.64898/2026.09.23.753732}
}

@article{cording2026-f93c5f98,
  author  = {Cording, A. and Verma, B. and Arous, A. and Rice, S. and Vine, H. and Blincowe, L. and Wainwright, S. M. and Singh, P. J. and others},
  title   = {{Rab11-exosome biogenesis regulators mediate Aβ-induced intercellular propagation of endolysosomal trafficking defects and neurodegeneration}},
  journal = {bioRxiv},
  year    = {2026},
  doi     = {10.64898/2026.09.17.752336},
  url     = {https://doi.org/10.64898/2026.09.17.752336}
}

@article{estellergauxax2026-42255968,
  author  = {Esteller-Gauxax, Diana and Guillén, Núria and Falgàs, Neus and Bosch, Beatriz and Tort-Merino, Adrià and Borrego-Écija, Sergi and Puey, Roger and Ruiz-Garcia, Raquel and others},
  title   = {{Atrophy signature for alpha-synuclein copathology in Alzheimer's disease}},
  journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)},
  year    = {2026},
  doi     = {10.1002/dad2.70347},
  pmid    = {42255968},
  url     = {https://doi.org/10.1002/dad2.70347}
}

@article{pittonrissardo2025-7b94959b,
  author  = {Pitton Rissardo, J. and Fornari Caprara, A. L.},
  title   = {{A Biophysical Framework for Neurodegeneration: Prioritizing Protein Homeostasis Over Aggregate Toxicity}},
  journal = {Preprints.org},
  year    = {2025},
  doi     = {10.20944/preprints202512.2722.v1},
  url     = {https://doi.org/10.20944/preprints202512.2722.v1}
}

@article{ai2026-41313318,
  author  = {Ai, Ruixue and Fang, Evandro F},
  title   = {{NAD+ restores proteostasis through splicing-dependent autophagy}},
  journal = {Autophagy},
  year    = {2026},
  doi     = {10.1080/15548627.2025.2596679},
  pmid    = {41313318},
  url     = {https://doi.org/10.1080/15548627.2025.2596679}
}

@article{jiang2025-40488453,
  author  = {Jiang, Shan and Srikanth, Malavika and Serpe, Rossana and Yavari, Shadi and Gaur, Pallavi and Collins, Galen Andrew and Soni, Rajesh and Menon, Vilas and others},
  title   = {{Early proteasome downregulation and dysfunction drive proteostasis failure in Alzheimer's disease}},
  journal = {Brain : a journal of neurology},
  year    = {2025},
  doi     = {10.1093/brain/awaf222},
  pmid    = {40488453},
  url     = {https://doi.org/10.1093/brain/awaf222}
}

@article{hayat2025-41877687,
  author  = {Hayat, Bushra and Alone, Debasmita Pankaj},
  title   = {{Unfolded proteins and aggregates: The role of proteostasis in pseudoexfoliation pathology}},
  journal = {Molecular vision},
  year    = {2025},
  pmid    = {41877687}
}

@article{holec2025-41206373,
  author  = {Holec, Sara A M and Khedmatgozar, Chase R and Schure, Shelbe J and Bartz, Jason C and Woerman, Amanda L},
  title   = {{Co-infection with two α-synuclein strains reveals novel synergistic interactions}},
  journal = {Acta neuropathologica},
  year    = {2025},
  doi     = {10.1007/s00401-025-02957-5},
  pmid    = {41206373},
  url     = {https://doi.org/10.1007/s00401-025-02957-5}
}

@article{zhang2025-41203507,
  author  = {Zhang, Yu P and Kedia, Shekhar and Klenerman, David},
  title   = {{Rethinking neurodegeneration through a co-proteinopathy lens}},
  journal = {Trends in neurosciences},
  year    = {2025},
  doi     = {10.1016/j.tins.2025.10.006},
  pmid    = {41203507},
  url     = {https://doi.org/10.1016/j.tins.2025.10.006}
}

@article{nasir2025-41229731,
  author  = {Nasir, Abdul R and Nouh, Claire Delpirou},
  title   = {{TDP-43-proteinopathy at the crossroads of tauopathy: on copathology and current and prospective biomarkers}},
  journal = {Frontiers in cellular neuroscience},
  year    = {2025},
  doi     = {10.3389/fncel.2025.1671419},
  pmid    = {41229731},
  url     = {https://doi.org/10.3389/fncel.2025.1671419}
}

@article{jamwal2025-41309196,
  author  = {Jamwal, Rajeshwer Singh and Sharma, Bhawani and Minerva and Gupta, Agamya and Misri, Swati and Shankaryan, Raju and Shah, Ruchi and Kumar, Rakesh},
  title   = {{Protein misfolding and its dual role in neurodegeneration and cancer progression}},
  journal = {Advances in protein chemistry and structural biology},
  year    = {2025},
  doi     = {10.1016/bs.apcsb.2025.10.001},
  pmid    = {41309196},
  url     = {https://doi.org/10.1016/bs.apcsb.2025.10.001}
}

@article{buck2025-41128923,
  author  = {Buck, Silas A and Malankhanova, Tuyana and Strader, Samuel and Ma, Eileen B and Yim, Sarah and Pratt, Harrison W and Ervin, John and Lee, Edward B and others},
  title   = {{LRRK2 kinase-mediated accumulation of lysosome-associated phospho-Rabs in tauopathies and synucleinopathies}},
  journal = {Acta neuropathologica},
  year    = {2025},
  doi     = {10.1007/s00401-025-02951-x},
  pmid    = {41128923},
  url     = {https://doi.org/10.1007/s00401-025-02951-x}
}

@article{augur2025-41085772,
  author  = {Augur, Zachary M and Fogo, Garrett M and Arbery, Mason R and Hsieh, Yi-Chen and Rao, Nalini R and Goyal, Kritika and Dexter, Emily and Bennett, David A and others},
  title   = {{Genetic and proteomic analysis identifies BAG3 as an amyloid-responsive regulator of neuronal proteostasis}},
  journal = {Acta neuropathologica},
  year    = {2025},
  doi     = {10.1007/s00401-025-02947-7},
  pmid    = {41085772},
  url     = {https://doi.org/10.1007/s00401-025-02947-7}
}

@article{salcedotacuma2025-41071871,
  author  = {Salcedo-Tacuma, David and Asad, Nadeem and Islam, Md Qamrul and Anderson, Raymond and Smith, David M},
  title   = {{Hyperactive 20S proteasome enhances proteostasis and ERAD in C. elegans via degradation of intrinsically disordered proteins}},
  journal = {Science advances},
  year    = {2025},
  doi     = {10.1126/sciadv.adx3014},
  pmid    = {41071871},
  url     = {https://doi.org/10.1126/sciadv.adx3014}
}

@article{augur2025-40898372,
  author  = {Augur, Zachary M and Fogo, Garrett M and Arbery, Mason R and Stern, Andrew M and Benoit, Courtney R and Hsieh, Yi-Chen and Young-Pearse, Tracy L},
  title   = {{Optineurin deficiency disrupts phosphorylated tau proteostasis and clusterin expression in human neurons}},
  journal = {Acta neuropathologica communications},
  year    = {2025},
  doi     = {10.1186/s40478-025-02103-y},
  pmid    = {40898372},
  url     = {https://doi.org/10.1186/s40478-025-02103-y}
}

@article{gao2025-40990068,
  author  = {Gao, Tong-Yao and Wang, Xu-Zheng and Xie, Yu-Han and Wang, Tong and Lu, Yun-Bi and Huang, Lu-Long and Chen, Cong and Zhang, Ming and others},
  title   = {{PINK1 deficiency permits the development of Lewy body dementia with coexisting Aβ pathology}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2025},
  doi     = {10.1002/alz.70730},
  pmid    = {40990068},
  url     = {https://doi.org/10.1002/alz.70730}
}

@article{palacios2025-40760071,
  author  = {Palacios, Adrián G and Zhang, Sarah X and Acosta, Mónica L},
  title   = {{Diabetic retinopathy and Alzheimer's disease: Convergence of the unfolded protein response in neurodegeneration}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2025},
  doi     = {10.1002/alz.70497},
  pmid    = {40760071},
  url     = {https://doi.org/10.1002/alz.70497}
}

@article{hein2025-40558538,
  author  = {Hein, Zaw Myo and Vishnumukkala, Thirupathirao and Karikalan, Barani and Alkatiri, Aisyah and Hussan, Farida and Jagadeesan, Saravanan and Kamaruzzaman, Mohd Amir and Ramli, Muhammad Danial Che and others},
  title   = {{Autophagy and Alzheimer's Disease: Mechanisms and Impact Beyond the Brain}},
  journal = {Cells},
  year    = {2025},
  doi     = {10.3390/cells14120911},
  pmid    = {40558538},
  url     = {https://doi.org/10.3390/cells14120911}
}

@article{li2025-40414310,
  author  = {Li, Lili and Li, Shiyin and Cai, Lei and Yang, Xiaofeng and Feng, Yifeng and Zhang, Liying and He, Xiaofei and Li, Mingyue},
  title   = {{Physical exercise mitigates the cognitive impairments by promoting ER-phagy in mice model of Alzheimer's disease}},
  journal = {Behavioural brain research},
  year    = {2025},
  doi     = {10.1016/j.bbr.2025.115650},
  pmid    = {40414310},
  url     = {https://doi.org/10.1016/j.bbr.2025.115650}
}

@article{tang2025-39988732,
  author  = {Tang, Qiyu and Tang, Keyi and Markby, Greg R and Parys, Maciej and Phadwal, Kanchan and MacRae, Vicky E and Corcoran, Brendan M},
  title   = {{Autophagy regulates cellular senescence by mediating the degradation of CDKN1A/p21 and CDKN2A/p16 through SQSTM1/p62-mediated selective autophagy in myxomatous mitral valve degeneration}},
  journal = {Autophagy},
  year    = {2025},
  doi     = {10.1080/15548627.2025.2469315},
  pmid    = {39988732},
  url     = {https://doi.org/10.1080/15548627.2025.2469315}
}

@article{khawaja2025-39910244,
  author  = {Khawaja, Rabia R and Martín-Segura, Adrián and Santiago-Fernández, Olaya and Sereda, Rebecca and Lindenau, Kristen and McCabe, Mericka and Macho-González, Adrián and Jafari, Maryam and others},
  title   = {{Sex-specific and cell-type-specific changes in chaperone-mediated autophagy across tissues during aging}},
  journal = {Nature aging},
  year    = {2025},
  doi     = {10.1038/s43587-024-00799-6},
  pmid    = {39910244},
  url     = {https://doi.org/10.1038/s43587-024-00799-6}
}

@article{chiu2025-39743215,
  author  = {Chiu, Yuanpu and Xia, Shangzhou and Qiao, Haowen and Zhao, Zhen},
  title   = {{Genetically Engineered Mouse Models for Alzheimer Disease and Frontotemporal Dementia: New Insights from Single-Cell and Spatial Transcriptomics}},
  journal = {The American journal of pathology},
  year    = {2025},
  doi     = {10.1016/j.ajpath.2024.11.006},
  pmid    = {39743215},
  url     = {https://doi.org/10.1016/j.ajpath.2024.11.006}
}

@article{endicott2024-39687864,
  author  = {Endicott, S Joseph},
  title   = {{Chaperone-mediated autophagy as a modulator of aging and longevity}},
  journal = {Frontiers in aging},
  year    = {2024},
  doi     = {10.3389/fragi.2024.1509400},
  pmid    = {39687864},
  url     = {https://doi.org/10.3389/fragi.2024.1509400}
}

@article{perdok2024-39613768,
  author  = {Perdok, Anika and Van Acker, Zoë P and Vrancx, Céline and Sannerud, Ragna and Vorsters, Inge and Verrengia, Assunta and Callaerts-Végh, Zsuzsanna and Creemers, Eline and others},
  title   = {{Altered expression of Presenilin2 impacts endolysosomal homeostasis and synapse function in Alzheimer's disease-relevant brain circuits}},
  journal = {Nature communications},
  year    = {2024},
  doi     = {10.1038/s41467-024-54777-y},
  pmid    = {39613768},
  url     = {https://doi.org/10.1038/s41467-024-54777-y}
}

@article{miyazaki2024-39251226,
  author  = {Miyazaki, Takehiro and Higashi, Shinji and Arai, Tetsuaki},
  title   = {{[Disease-modifying Drugs for non-Alzheimer Dementias]}},
  journal = {Brain and nerve = Shinkei kenkyu no shinpo},
  year    = {2024},
  doi     = {10.11477/mf.1416202733},
  pmid    = {39251226},
  url     = {https://doi.org/10.11477/mf.1416202733}
}

@article{lin2024-39281281,
  author  = {Lin, Hongru and Zhang, Chen and Gao, Yehui and Zhou, Yi and Ma, Botian and Jiang, Jinyun and Long, Xue and Yimamu, Nuerziya and others},
  title   = {{HLH-30/TFEB modulates autophagy to improve proteostasis in Aβ transgenic Caenorhabditis elegans}},
  journal = {Frontiers in pharmacology},
  year    = {2024},
  doi     = {10.3389/fphar.2024.1433030},
  pmid    = {39281281},
  url     = {https://doi.org/10.3389/fphar.2024.1433030}
}

@article{thapa2024-39216694,
  author  = {Thapa, Riya and Bhat, Asif Ahmad and Shahwan, Moyad and Ali, Haider and PadmaPriya, G and Bansal, Pooja and Rajotiya, Sumit and Barwal, Amit and others},
  title   = {{Proteostasis disruption and senescence in Alzheimer's disease pathways to neurodegeneration}},
  journal = {Brain research},
  year    = {2024},
  doi     = {10.1016/j.brainres.2024.149202},
  pmid    = {39216694},
  url     = {https://doi.org/10.1016/j.brainres.2024.149202}
}

@article{ye2024-38869076,
  author  = {Ye, Yu and Jia, Penghui and Miao, Jiafan and Wang, Yicheng and Li, Zibo and Lin, Yuxin and He, Miao and Liu, Shurui and others},
  title   = {{CCDC50 mediates the clearance of protein aggregates to prevent cellular proteotoxicity}},
  journal = {Autophagy},
  year    = {2024},
  doi     = {10.1080/15548627.2024.2367183},
  pmid    = {38869076},
  url     = {https://doi.org/10.1080/15548627.2024.2367183}
}

@article{robinson2024-38896345,
  author  = {Robinson, John L and Suh, EunRan and Xu, Yan and Hurtig, Howard I and Elman, Lauren and McMillan, Corey T and Irwin, David J and Porta, Sílvia and others},
  title   = {{Annexin A11 aggregation in FTLD-TDP type C and related neurodegenerative disease proteinopathies}},
  journal = {Acta neuropathologica},
  year    = {2024},
  doi     = {10.1007/s00401-024-02753-7},
  pmid    = {38896345},
  url     = {https://doi.org/10.1007/s00401-024-02753-7}
}

@article{ferrari2024-38865459,
  author  = {Ferrari, Luca and Bauer, Bernd and Qiu, Yue and Schuschnig, Martina and Klotz, Sigrid and Anrather, Dorothea and Juretschke, Thomas and Beli, Petra and others},
  title   = {{Tau fibrils evade autophagy by excessive p62 coating and TAX1BP1 exclusion}},
  journal = {Science advances},
  year    = {2024},
  doi     = {10.1126/sciadv.adm8449},
  pmid    = {38865459},
  url     = {https://doi.org/10.1126/sciadv.adm8449}
}

@article{kinger2024-38797543,
  author  = {Kinger, Sumit and Jagtap, Yuvraj Anandrao and Kumar, Prashant and Choudhary, Akash and Prasad, Amit and Prajapati, Vijay Kumar and Kumar, Amit and Mehta, Gunjan and others},
  title   = {{Proteostasis in neurodegenerative diseases}},
  journal = {Advances in clinical chemistry},
  year    = {2024},
  doi     = {10.1016/bs.acc.2024.04.002},
  pmid    = {38797543},
  url     = {https://doi.org/10.1016/bs.acc.2024.04.002}
}

@article{dasilva2024-38615035,
  author  = {da Silva, Marina I Oliveira and Santejo, Miguel and Babcock, Isaac W and Magalhães, Ana and Minamide, Laurie S and Won, Seok-Joon and Castillo, Erika and Gerhardt, Ellen and others},
  title   = {{α-Synuclein triggers cofilin pathology and dendritic spine impairment via a PrPC-CCR5 dependent pathway}},
  journal = {Cell death \& disease},
  year    = {2024},
  doi     = {10.1038/s41419-024-06630-9},
  pmid    = {38615035},
  url     = {https://doi.org/10.1038/s41419-024-06630-9}
}

@article{panwar2024-38570333,
  author  = {Panwar, Surbhi and Uniyal, Prerna and Kukreti, Neelima and Hashmi, Afreen and Verma, Shivani and Arya, Aanchal and Joshi, Gaurav},
  title   = {{Role of autophagy and proteostasis in neurodegenerative diseases: Exploring the therapeutic interventions}},
  journal = {Chemical biology \& drug design},
  year    = {2024},
  doi     = {10.1111/cbdd.14515},
  pmid    = {38570333},
  url     = {https://doi.org/10.1111/cbdd.14515}
}

@article{schuster2024-38429929,
  author  = {Schuster, Kristen H and Zalon, Annie J and DiFranco, Danielle M and Putka, Alexandra F and Stec, Nicholas R and Jarrah, Sabrina I and Naeem, Arsal and Haque, Zaid and others},
  title   = {{ASOs are an effective treatment for disease-associated oligodendrocyte signatures in premanifest and symptomatic SCA3 mice}},
  journal = {Molecular therapy : the journal of the American Society of Gene Therapy},
  year    = {2024},
  doi     = {10.1016/j.ymthe.2024.02.033},
  pmid    = {38429929},
  url     = {https://doi.org/10.1016/j.ymthe.2024.02.033}
}

@article{mintoo2024-38174740,
  author  = {Mintoo, Mubashir and Rajagopalan, Vinodh and O'Bryan, John P},
  title   = {{Intersectin - many facets of a scaffold protein}},
  journal = {Biochemical Society transactions},
  year    = {2024},
  doi     = {10.1042/bst20211241},
  pmid    = {38174740},
  url     = {https://doi.org/10.1042/bst20211241}
}

@article{almeida2024-38417436,
  author  = {Almeida, Maria Camila and Eger, Sarah J and He, Caroline and Audouard, Morgane and Nikitina, Arina and Glasauer, Stella M K and Han, Dasol and Mejía-Cupajita, Barbara and others},
  title   = {{Single-nucleus RNA sequencing demonstrates an autosomal dominant Alzheimer's disease profile and possible mechanisms of disease protection}},
  journal = {Neuron},
  year    = {2024},
  doi     = {10.1016/j.neuron.2024.02.009},
  pmid    = {38417436},
  url     = {https://doi.org/10.1016/j.neuron.2024.02.009}
}

@article{irwin2024-38278991,
  author  = {Irwin, K. E. and Jasin, P. and Braunstein, K. E. and Sinha, I. R. and Garret, M. A. and Bowden, K. D. and Chang, K. and Troncoso, J. C. and others},
  title   = {{A fluid biomarker reveals loss of TDP-43 splicing repression in presymptomatic ALS-FTD}},
  journal = {Nature medicine},
  year    = {2024},
  doi     = {10.1038/s41591-023-02788-5},
  pmid    = {38278991},
  url     = {https://doi.org/10.1038/s41591-023-02788-5}
}

@article{ryan2024-38101818,
  author  = {Ryan, Laura and Rubinsztein, David C},
  title   = {{The autophagy of stress granules}},
  journal = {FEBS letters},
  year    = {2024},
  doi     = {10.1002/1873-3468.14787},
  pmid    = {38101818},
  url     = {https://doi.org/10.1002/1873-3468.14787}
}

@article{gallrein2023-38100354,
  author  = {Gallrein, Christian and Williams, Ashley B and Meyer, David H and Messling, Jan-Erik and Garcia, Antonio and Schumacher, Björn},
  title   = {{baz-2 enhances systemic proteostasis in vivo by regulating acetylcholine metabolism}},
  journal = {Cell reports},
  year    = {2023},
  doi     = {10.1016/j.celrep.2023.113577},
  pmid    = {38100354},
  url     = {https://doi.org/10.1016/j.celrep.2023.113577}
}

@article{makeeva2023-38069121,
  author  = {Makeeva, Vladlena S and Dyrkheeva, Nadezhda S and Lavrik, Olga I and Zakian, Suren M and Malakhova, Anastasia A},
  title   = {{Mutant-Huntingtin Molecular Pathways Elucidate New Targets for Drug Repurposing}},
  journal = {International journal of molecular sciences},
  year    = {2023},
  doi     = {10.3390/ijms242316798},
  pmid    = {38069121},
  url     = {https://doi.org/10.3390/ijms242316798}
}

@article{sita2023-38003389,
  author  = {Sita, Giulia and Graziosi, Agnese and Corrieri, Camilla and Ghelli, Luca and Angelini, Sabrina and Cortelli, Pietro and Hrelia, Patrizia and Morroni, Fabiana},
  title   = {{The Unfolded Protein Response in a Murine Model of Alzheimer's Disease: Looking for Predictors}},
  journal = {International journal of molecular sciences},
  year    = {2023},
  doi     = {10.3390/ijms242216200},
  pmid    = {38003389},
  url     = {https://doi.org/10.3390/ijms242216200}
}

@article{barmaki2023-38020769,
  author  = {Barmaki, Haleh and Nourazarian, Alireza and Khaki-Khatibi, Fatemeh},
  title   = {{Proteostasis and neurodegeneration: a closer look at autophagy in Alzheimer's disease}},
  journal = {Frontiers in aging neuroscience},
  year    = {2023},
  doi     = {10.3389/fnagi.2023.1281338},
  pmid    = {38020769},
  url     = {https://doi.org/10.3389/fnagi.2023.1281338}
}

@article{li2024-38486986,
  author  = {Li, Yixian and Yang, Peng and Meng, Ran and Xu, Shuting and Zhou, Lingling and Qian, Kang and Wang, Pengzhen and Cheng, Yunlong and others},
  title   = {{Multidimensional autophagy nano-regulator boosts Alzheimer's disease treatment by improving both extra/intraneuronal homeostasis}},
  journal = {Acta pharmaceutica Sinica. B},
  year    = {2024},
  doi     = {10.1016/j.apsb.2023.10.009},
  pmid    = {38486986},
  url     = {https://doi.org/10.1016/j.apsb.2023.10.009}
}

@article{mariner2024-37749371,
  author  = {Mariner, Blaise L and Rodriguez, Antonio S and Heath, Olivia C and McCormick, Mark A},
  title   = {{Induction of proteasomal activity in mammalian cells by lifespan-extending tRNA synthetase inhibitors}},
  journal = {GeroScience},
  year    = {2024},
  doi     = {10.1007/s11357-023-00938-8},
  pmid    = {37749371},
  url     = {https://doi.org/10.1007/s11357-023-00938-8}
}

@article{sanghai2023-37759540,
  author  = {Sanghai, Nitesh and Tranmer, Geoffrey K},
  title   = {{Biochemical and Molecular Pathways in Neurodegenerative Diseases: An Integrated View}},
  journal = {Cells},
  year    = {2023},
  doi     = {10.3390/cells12182318},
  pmid    = {37759540},
  url     = {https://doi.org/10.3390/cells12182318}
}

@article{deruyter2023-37640753,
  author  = {de Ruyter, Frederique J Hart and Morrema, Tjado H J and den Haan, Jurre and Gase, Gina and Twisk, Jos W R and de Boer, Johannes F and Scheltens, Philip and Bouwman, Femke H and others},
  title   = {{α-Synuclein pathology in post-mortem retina and optic nerve is specific for α-synucleinopathies}},
  journal = {NPJ Parkinson's disease},
  year    = {2023},
  doi     = {10.1038/s41531-023-00570-5},
  pmid    = {37640753},
  url     = {https://doi.org/10.1038/s41531-023-00570-5}
}

@article{chen2023-37674720,
  author  = {Chen, Sheng and Puri, Anuradhika and Bell, Braxton and Fritsche, Joseph and Palacios, Hector and Balch, Maurie and Sprunger, Macy and Howard, Matthew and others},
  title   = {{HtrA1 prevents and reverses α-synuclein aggregation, rendering it non-toxic and seeding incompetent}},
  journal = {Nature communications},
  year    = {2023},
  doi     = {10.21203/rs.3.rs-2570571/v1},
  pmid    = {37674720},
  url     = {https://doi.org/10.21203/rs.3.rs-2570571/v1}
}

@article{mehrabipour2023-37626864,
  author  = {Mehrabipour, Mehrnaz and Jasemi, Neda S Kazemein and Dvorsky, Radovan and Ahmadian, Mohammad R},
  title   = {{A Systematic Compilation of Human SH3 Domains: A Versatile Superfamily in Cellular Signaling}},
  journal = {Cells},
  year    = {2023},
  doi     = {10.3390/cells12162054},
  pmid    = {37626864},
  url     = {https://doi.org/10.3390/cells12162054}
}

@article{daly2023-37248224,
  author  = {Daly, James L and Danson, Chris M and Lewis, Philip A and Zhao, Lu and Riccardo, Sara and Di Filippo, Lucio and Cacchiarelli, Davide and Lee, Daehoon and others},
  title   = {{Multi-omic approach characterises the neuroprotective role of retromer in regulating lysosomal health}},
  journal = {Nature communications},
  year    = {2023},
  doi     = {10.1038/s41467-023-38719-8},
  pmid    = {37248224},
  url     = {https://doi.org/10.1038/s41467-023-38719-8}
}

@article{pilotto2023-37102457,
  author  = {Pilotto, Andrea and Bongianni, Matilde and Tirloni, Clara and Galli, Alice and Padovani, Alessandro and Zanusso, Gianluigi},
  title   = {{CSF alpha-synuclein aggregates by seed amplification and clinical presentation of AD}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2023},
  doi     = {10.1002/alz.13109},
  pmid    = {37102457},
  url     = {https://doi.org/10.1002/alz.13109}
}

@article{tsoi2023-36834792,
  author  = {Tsoi, Phoebe S and Quan, My Diem and Ferreon, Josephine C and Ferreon, Allan Chris M},
  title   = {{Aggregation of Disordered Proteins Associated with Neurodegeneration}},
  journal = {International journal of molecular sciences},
  year    = {2023},
  doi     = {10.3390/ijms24043380},
  pmid    = {36834792},
  url     = {https://doi.org/10.3390/ijms24043380}
}

@article{cozachenco2023-36693451,
  author  = {Cozachenco, Danielle and Ribeiro, Felipe C and Ferreira, Sergio T},
  title   = {{Defective proteostasis in Alzheimer's disease}},
  journal = {Ageing research reviews},
  year    = {2023},
  doi     = {10.1016/j.arr.2023.101862},
  pmid    = {36693451},
  url     = {https://doi.org/10.1016/j.arr.2023.101862}
}

@article{elia2023-36712069,
  author  = {Elia, Lisa and Herting, Bianca and Alijagic, Amela and Buselli, Christina and Wong, Leela and Morrison, Grace and Prado, Miguel A and Paulo, Joao A and others},
  title   = {{Frontotemporal Dementia Patient Neurons With Progranulin Deficiency Display Protein Dyshomeostasis}},
  journal = {bioRxiv : the preprint server for biology},
  year    = {2023},
  doi     = {10.1101/2023.01.18.524611},
  pmid    = {36712069},
  url     = {https://doi.org/10.1101/2023.01.18.524611}
}

@article{chu2023-36633448,
  author  = {Chu, Yuan-Ping and Ho, Pei-Chuan and Tsai, Kuen-Jer},
  title   = {{TTR (transthyretin) leads the autophagy disaster relief team against TARDBP/TDP-43 proteinopathy}},
  journal = {Autophagy},
  year    = {2023},
  doi     = {10.1080/15548627.2023.2167690},
  pmid    = {36633448},
  url     = {https://doi.org/10.1080/15548627.2023.2167690}
}

@article{makhdoomi2023-36208459,
  author  = {Makhdoomi, Sajjad and Ariafar, Saba and Mirzaei, Fatemeh and Mohammadi, Mojdeh},
  title   = {{Aluminum neurotoxicity and autophagy: a mechanistic view}},
  journal = {Neurological research},
  year    = {2023},
  doi     = {10.1080/01616412.2022.2132727},
  pmid    = {36208459},
  url     = {https://doi.org/10.1080/01616412.2022.2132727}
}

@article{lu2022-36262883,
  author  = {Lu, Ranran and Zhang, Lijie and Yang, Xinling},
  title   = {{Interaction between autophagy and the NLRP3 inflammasome in Alzheimer's and Parkinson's disease}},
  journal = {Frontiers in aging neuroscience},
  year    = {2022},
  doi     = {10.3389/fnagi.2022.1018848},
  pmid    = {36262883},
  url     = {https://doi.org/10.3389/fnagi.2022.1018848}
}

@article{dhakal2022-36116552,
  author  = {Dhakal, Shailendra and Robang, Alicia S and Bhatt, Nemil and Puangmalai, Nicha and Fung, Leiana and Kayed, Rakez and Paravastu, Anant K and Rangachari, Vijayaraghavan},
  title   = {{Distinct neurotoxic TDP-43 fibril polymorphs are generated by heterotypic interactions with α-Synuclein}},
  journal = {The Journal of biological chemistry},
  year    = {2022},
  doi     = {10.1016/j.jbc.2022.102498},
  pmid    = {36116552},
  url     = {https://doi.org/10.1016/j.jbc.2022.102498}
}

@article{susjanleite2022-35979366,
  author  = {Sušjan-Leite, Petra and Ramuta, Taja Železnik and Boršić, Elvira and Orehek, Sara and Hafner-Bratkovič, Iva},
  title   = {{Supramolecular organizing centers at the interface of inflammation and neurodegeneration}},
  journal = {Frontiers in immunology},
  year    = {2022},
  doi     = {10.3389/fimmu.2022.940969},
  pmid    = {35979366},
  url     = {https://doi.org/10.3389/fimmu.2022.940969}
}

@article{lee2022-35654956,
  author  = {Lee, J. H. and Yang, D. S. and Goulbourne, C. N. and Im, E. and Stavrides, P. and Pensalfini, A. and Chan, H. and Bouchet-Marquis, C. and others},
  title   = {{Faulty autolysosome acidification in Alzheimer's disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques}},
  journal = {Nature neuroscience},
  year    = {2022},
  doi     = {10.1038/s41593-022-01084-8},
  pmid    = {35654956},
  url     = {https://doi.org/10.1038/s41593-022-01084-8}
}

@article{ntsapi2022-40396009,
  author  = {Ntsapi, Claudia M and du Toit, Andre and Loos, Ben},
  title   = {{Favorably against the odds - autophagy control despite advanced amyloid- ß toxicity}},
  journal = {Autophagy reports},
  year    = {2022},
  doi     = {10.1080/27694127.2022.2082631},
  pmid    = {40396009},
  url     = {https://doi.org/10.1080/27694127.2022.2082631}
}

@article{jiang2022-35489321,
  author  = {Jiang, Li and Qin, Yan and Zhao, Yu-Wen and Zeng, Qian and Pan, Hong-Xu and Liu, Zhen-Hua and Sun, Qi-Ying and Xu, Qian and others},
  title   = {{PSEN1 G417S mutation in a Chinese pedigree causing early-onset parkinsonism with cognitive impairment}},
  journal = {Neurobiology of aging},
  year    = {2022},
  doi     = {10.1016/j.neurobiolaging.2022.03.016},
  pmid    = {35489321},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2022.03.016}
}

@article{liu2022-35395400,
  author  = {Liu, Wei and Wang, Gang and Wang, Zhiwen and Wang, Guan and Huang, Jianping and Liu, Bo},
  title   = {{Repurposing small-molecule drugs for modulating toxic protein aggregates in neurodegenerative diseases}},
  journal = {Drug discovery today},
  year    = {2022},
  doi     = {10.1016/j.drudis.2022.04.003},
  pmid    = {35395400},
  url     = {https://doi.org/10.1016/j.drudis.2022.04.003}
}

@article{tan2022-35454096,
  author  = {Tan, Li Yang and Tang, Kwan Hou and Lim, Lynette Yu You and Ong, Jia Xin and Park, Hyokeun and Jung, Sangyong},
  title   = {{α-Synuclein at the Presynaptic Axon Terminal as a Double-Edged Sword}},
  journal = {Biomolecules},
  year    = {2022},
  doi     = {10.3390/biom12040507},
  pmid    = {35454096},
  url     = {https://doi.org/10.3390/biom12040507}
}

@article{eshraghi2022-35304223,
  author  = {Eshraghi, Mehdi and Ahmadi, Mazaher and Afshar, Saeid and Lorzadeh, Shahrokh and Adlimoghaddam, Aida and Jalal, Nahid Rezvani and West, Ryan and Dastghaib, Sanaz and others},
  title   = {{Enhancing autophagy in Alzheimer's disease through drug repositioning}},
  journal = {Pharmacology \& therapeutics},
  year    = {2022},
  doi     = {10.1016/j.pharmthera.2022.108171},
  pmid    = {35304223},
  url     = {https://doi.org/10.1016/j.pharmthera.2022.108171}
}

@article{munari2022-35107860,
  author  = {Munari, Francesca and Mollica, Luca and Valente, Carlo and Parolini, Francesca and Kachoie, Elham Ataie and Arrigoni, Giorgio and D'Onofrio, Mariapina and Capaldi, Stefano and others},
  title   = {{Structural Basis for Chaperone-Independent Ubiquitination of Tau Protein by Its E3 Ligase CHIP}},
  journal = {Angewandte Chemie (International ed. in English)},
  year    = {2022},
  doi     = {10.1002/anie.202112374},
  pmid    = {35107860},
  url     = {https://doi.org/10.1002/anie.202112374}
}

@article{krogsaeter2022-35144097,
  author  = {Krogsaeter, Einar and Rosato, Anna Scotto and Grimm, Christian},
  title   = {{TRPMLs and TPCs: Targets for lysosomal storage and neurodegenerative disease therapy?}},
  journal = {Cell calcium},
  year    = {2022},
  doi     = {10.1016/j.ceca.2022.102553},
  pmid    = {35144097},
  url     = {https://doi.org/10.1016/j.ceca.2022.102553}
}

@article{tecalcocruz2022-35083609,
  author  = {Tecalco-Cruz, Angeles C and Pedraza-Chaverri, José and Briones-Herrera, Alfredo and Cruz-Ramos, Eduardo and López-Canovas, Lilia and Zepeda-Cervantes, Jesús},
  title   = {{Protein degradation-associated mechanisms that are affected in Alzheimer´s disease}},
  journal = {Molecular and cellular biochemistry},
  year    = {2022},
  doi     = {10.1007/s11010-021-04334-8},
  pmid    = {35083609},
  url     = {https://doi.org/10.1007/s11010-021-04334-8}
}

@article{inuzuka2022-35237768,
  author  = {Inuzuka, Hiroyuki and Liu, Jing and Wei, Wenyi and Rezaeian, Abdol-Hossein},
  title   = {{PROTACs technology for treatment of Alzheimer's disease: Advances and perspectives}},
  journal = {Acta materia medica},
  year    = {2022},
  doi     = {10.15212/amm-2021-0001},
  pmid    = {35237768},
  url     = {https://doi.org/10.15212/amm-2021-0001}
}

@article{berdynski2022-36031890,
  author  = {Berdyński, Mariusz and Ludwiczak, Jan and Barczak, Anna and Barcikowska-Kotowicz, Maria and Kuźma-Kozakiewicz, Magdalena and Dunin-Horkawicz, Stanisław and Żekanowski, Cezary and Borzemska, Beata},
  title   = {{TREM2 Gene Compound Heterozygosity in Neurodegenerative Disorders}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2022},
  doi     = {10.3233/jad-220210},
  pmid    = {36031890},
  url     = {https://doi.org/10.3233/jad-220210}
}

@article{tran2022-34949835,
  author  = {Tran, H. and Moazami, M. P. and Yang, H. and McKenna-Yasek, D. and Douthwright, C. L. and Pinto, C. and Metterville, J. and Shin, M. and others},
  title   = {{Suppression of mutant C9orf72 expression by a potent mixed backbone antisense oligonucleotide}},
  journal = {Nature medicine},
  year    = {2022},
  doi     = {10.1038/s41591-021-01557-6},
  pmid    = {34949835},
  url     = {https://doi.org/10.1038/s41591-021-01557-6}
}

@article{simon2021-34798911,
  author  = {Simon, Christopher and Soga, Tomoko and Okano, Hirotaka James and Parhar, Ishwar},
  title   = {{α-Synuclein-mediated neurodegeneration in Dementia with Lewy bodies: the pathobiology of a paradox}},
  journal = {Cell \& bioscience},
  year    = {2021},
  doi     = {10.1186/s13578-021-00709-y},
  pmid    = {34798911},
  url     = {https://doi.org/10.1186/s13578-021-00709-y}
}

@article{hommen2022-34689261,
  author  = {Hommen, Franziska and Bilican, Saygın and Vilchez, David},
  title   = {{Protein clearance strategies for disease intervention}},
  journal = {Journal of neural transmission (Vienna, Austria : 1996)},
  year    = {2022},
  doi     = {10.1007/s00702-021-02431-y},
  pmid    = {34689261},
  url     = {https://doi.org/10.1007/s00702-021-02431-y}
}

@article{lloyd2021-34503546,
  author  = {Lloyd, Grace M and Dhillon, Jess-Karan S and Gorion, Kimberly-Marie M and Riffe, Cara and Fromholt, Susan E and Xia, Yuxing and Giasson, Benoit I and Borchelt, David R},
  title   = {{Collusion of α-Synuclein and Aβ aggravating co-morbidities in a novel prion-type mouse model}},
  journal = {Molecular neurodegeneration},
  year    = {2021},
  doi     = {10.1186/s13024-021-00486-9},
  pmid    = {34503546},
  url     = {https://doi.org/10.1186/s13024-021-00486-9}
}

@article{uddin2021-34339860,
  author  = {Uddin, Md Sahab and Yu, Wing Shan and Lim, Lee Wei},
  title   = {{Exploring ER stress response in cellular aging and neuroinflammation in Alzheimer's disease}},
  journal = {Ageing research reviews},
  year    = {2021},
  doi     = {10.1016/j.arr.2021.101417},
  pmid    = {34339860},
  url     = {https://doi.org/10.1016/j.arr.2021.101417}
}

@article{xu2021-34291435,
  author  = {Xu, X. and Sun, Y. and Cen, X. and Shan, B. and Zhao, Q. and Xie, T. and Wang, Z. and Hou, T. and others},
  title   = {{Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model}},
  journal = {Protein \& cell},
  year    = {2021},
  doi     = {10.1007/s13238-021-00858-3},
  pmid    = {34291435},
  url     = {https://doi.org/10.1007/s13238-021-00858-3}
}

@article{nakamura2021-34224817,
  author  = {Nakamura, Tomohiro and Oh, Chang-Ki and Zhang, Xu and Lipton, Stuart A},
  title   = {{Protein S-nitrosylation and oxidation contribute to protein misfolding in neurodegeneration}},
  journal = {Free radical biology \& medicine},
  year    = {2021},
  doi     = {10.1016/j.freeradbiomed.2021.07.002},
  pmid    = {34224817},
  url     = {https://doi.org/10.1016/j.freeradbiomed.2021.07.002}
}

@article{hyun2021-34202541,
  author  = {Hyun, Soonsil and Shin, Dongyun},
  title   = {{Chemical-Mediated Targeted Protein Degradation in Neurodegenerative Diseases}},
  journal = {Life (Basel, Switzerland)},
  year    = {2021},
  doi     = {10.3390/life11070607},
  pmid    = {34202541},
  url     = {https://doi.org/10.3390/life11070607}
}

@article{bourdenx2021-34110247,
  author  = {Bourdenx, Mathieu and Gavathiotis, Evripidis and Cuervo, Ana Maria},
  title   = {{Chaperone-mediated autophagy: a gatekeeper of neuronal proteostasis}},
  journal = {Autophagy},
  year    = {2021},
  doi     = {10.1080/15548627.2021.1935007},
  pmid    = {34110247},
  url     = {https://doi.org/10.1080/15548627.2021.1935007}
}

@article{moujalled2021-34099897,
  author  = {Moujalled, D. and Strasser, A. and Liddell, JR.},
  title   = {{Molecular mechanisms of cell death in neurological diseases}},
  journal = {Cell death and differentiation},
  year    = {2021},
  doi     = {10.1038/s41418-021-00814-y},
  pmid    = {34099897},
  url     = {https://doi.org/10.1038/s41418-021-00814-y}
}

@article{hung2021-34133918,
  author  = {Hung, C. and Tuck, E. and Stubbs, V. and van der Lee, S. J. and Aalfs, C. and van Spaendonk, R. and Scheltens, P. and Hardy, J. and others},
  title   = {{SORL1 deficiency in human excitatory neurons causes APP-dependent defects in the endolysosome-autophagy network}},
  journal = {Cell reports},
  year    = {2021},
  doi     = {10.1016/j.celrep.2021.109259},
  pmid    = {34133918},
  url     = {https://doi.org/10.1016/j.celrep.2021.109259}
}

@article{chua2022-34057020,
  author  = {Chua, Jason P and De Calbiac, Hortense and Kabashi, Edor and Barmada, Sami J},
  title   = {{Autophagy and ALS: mechanistic insights and therapeutic implications}},
  journal = {Autophagy},
  year    = {2022},
  doi     = {10.1080/15548627.2021.1926656},
  pmid    = {34057020},
  url     = {https://doi.org/10.1080/15548627.2021.1926656}
}

@article{bluhm2021-34064208,
  author  = {Bluhm, Alexandra and Schrempel, Sarah and von Hörsten, Stephan and Schulze, Anja and Roßner, Steffen},
  title   = {{Proteolytic α-Synuclein Cleavage in Health and Disease}},
  journal = {International journal of molecular sciences},
  year    = {2021},
  doi     = {10.3390/ijms22115450},
  pmid    = {34064208},
  url     = {https://doi.org/10.3390/ijms22115450}
}

@article{li2021-34016162,
  author  = {Li, D. and McIntosh, C. S. and Mastaglia, F. L. and Wilton, S. D. and Aung-Htut, M. T.},
  title   = {{Neurodegenerative diseases: a hotbed for splicing defects and the potential therapies}},
  journal = {Translational neurodegeneration},
  year    = {2021},
  doi     = {10.1186/s40035-021-00240-7},
  pmid    = {34016162},
  url     = {https://doi.org/10.1186/s40035-021-00240-7}
}

@article{park2021-33924878,
  author  = {Park, Hyungsun and Kim, Jongyoon and Shin, Chihoon and Lee, Seongju},
  title   = {{Intersection between Redox Homeostasis and Autophagy: Valuable Insights into Neurodegeneration}},
  journal = {Antioxidants (Basel, Switzerland)},
  year    = {2021},
  doi     = {10.3390/antiox10050694},
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}

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  title   = {{Dementia with Lewy bodies: emerging drug targets and therapeutics}},
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}

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  title   = {{Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome}},
  journal = {Cell},
  year    = {2021},
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  pmid    = {33891876},
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@article{beckers2021-33632058,
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  title   = {{C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels}},
  journal = {Autophagy},
  year    = {2021},
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@article{franic2021-33406777,
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  title   = {{Nuclear Ubiquitin-Proteasome Pathways in Proteostasis Maintenance}},
  journal = {Biomolecules},
  year    = {2021},
  doi     = {10.3390/biom11010054},
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@article{mendell2021-33309881,
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  title   = {{Current Clinical Applications of In Vivo Gene Therapy with AAVs}},
  journal = {Molecular therapy : the journal of the American Society of Gene Therapy},
  year    = {2021},
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@article{omer2020-33049246,
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  title   = {{Autophagy and heat-shock response impair stress granule assembly during cellular senescence}},
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@article{almeida2020-32739009,
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@article{shen2020-32531261,
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  title   = {{TDP-1/TDP-43 potentiates human α-Synuclein (HASN) neurodegeneration in Caenorhabditis elegans}},
  journal = {Biochimica et biophysica acta. Molecular basis of disease},
  year    = {2020},
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@article{schweighauser2020-32461689,
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  title   = {{Structures of α-synuclein filaments from multiple system atrophy}},
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@article{iwasaki2020-32363728,
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  year    = {2020},
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@article{hohn2020-32308803,
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  title   = {{Proteostasis Failure in Neurodegenerative Diseases: Focus on Oxidative Stress}},
  journal = {Oxidative medicine and cellular longevity},
  year    = {2020},
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}

@article{bharadwaj2020-31962153,
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  title   = {{Autophagy modulates Aβ accumulation and formation of aggregates in yeast}},
  journal = {Molecular and cellular neurosciences},
  year    = {2020},
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@article{zhang2019-31992981,
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  title   = {{TDP-43 and Limbic-Predominant Age-Related TDP-43 Encephalopathy}},
  journal = {Frontiers in aging neuroscience},
  year    = {2019},
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@article{fanning2020-31909184,
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  year    = {2020},
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@article{sathyaprakash2020-32865792,
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  title   = {{Development of LNA Gapmer Oligonucleotide-Based Therapy for ALS/FTD Caused by the C9orf72 Repeat Expansion}},
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  year    = {2020},
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@article{harris2020-32274758,
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  title   = {{The Ubiquitin System in Alzheimer's Disease}},
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  year    = {2020},
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}

@article{hwang2019-31634675,
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  title   = {{Autophagy and synaptic plasticity: epigenetic regulation}},
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  year    = {2019},
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@article{jiang2019-31667754,
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  title   = {{Pathogenic Mechanisms and Therapy Development for C9orf72 Amyotrophic Lateral Sclerosis/Frontotemporal Dementia}},
  journal = {Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics},
  year    = {2019},
  doi     = {10.1007/s13311-019-00797-2},
  pmid    = {31667754},
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@article{chung2019-31556259,
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  title   = {{Modeling α-Synuclein Propagation with Preformed Fibril Injections}},
  journal = {Journal of movement disorders},
  year    = {2019},
  doi     = {10.14802/jmd.19046},
  pmid    = {31556259},
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@article{pulst2019-31165208,
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  title   = {{[Antisense therapies for neurological diseases]}},
  journal = {Der Nervenarzt},
  year    = {2019},
  doi     = {10.1007/s00115-019-0724-4},
  pmid    = {31165208},
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}

@article{meade2019-31331359,
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  title   = {{Alpha-synuclein structure and Parkinson's disease - lessons and emerging principles}},
  journal = {Molecular neurodegeneration},
  year    = {2019},
  doi     = {10.1186/s13024-019-0329-1},
  pmid    = {31331359},
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}

@article{hipp2019-30733602,
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  title   = {{The proteostasis network and its decline in ageing}},
  journal = {Nature reviews. Molecular cell biology},
  year    = {2019},
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  pmid    = {30733602},
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}

@article{strohm2020-31132469,
  author  = {Strohm, Laura and Behrends, Christian},
  title   = {{Glia-specific autophagy dysfunction in ALS}},
  journal = {Seminars in cell \& developmental biology},
  year    = {2020},
  doi     = {10.1016/j.semcdb.2019.05.024},
  pmid    = {31132469},
  url     = {https://doi.org/10.1016/j.semcdb.2019.05.024}
}

@article{dimeco2020-31262433,
  author  = {Di Meco, Antonio and Curtis, Mary Elizabeth and Lauretti, Elisabetta and Praticò, Domenico},
  title   = {{Autophagy Dysfunction in Alzheimer's Disease: Mechanistic Insights and New Therapeutic Opportunities}},
  journal = {Biological psychiatry},
  year    = {2020},
  doi     = {10.1016/j.biopsych.2019.05.008},
  pmid    = {31262433},
  url     = {https://doi.org/10.1016/j.biopsych.2019.05.008}
}

@article{senturk2019-31032688,
  author  = {Şentürk, Mümine and Mao, Dongxue and Bellen, Hugo J},
  title   = {{Loss of proteins associated with amyotrophic lateral sclerosis affects lysosomal acidification via different routes}},
  journal = {Autophagy},
  year    = {2019},
  doi     = {10.1080/15548627.2019.1609863},
  pmid    = {31032688},
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}

@article{doria2019-31004752,
  author  = {Doria, Margaux and Nury, Thomas and Delmas, Dominique and Moreau, Thibault and Lizard, Gérard and Vejux, Anne},
  title   = {{Protective function of autophagy during VLCFA-induced cytotoxicity in a neurodegenerative cell model}},
  journal = {Free radical biology \& medicine},
  year    = {2019},
  doi     = {10.1016/j.freeradbiomed.2019.04.016},
  pmid    = {31004752},
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@article{scoles2019-31119194,
  author  = {Scoles, D. R. and Minikel, E. V. and Pulst, S. M.},
  title   = {{Antisense oligonucleotides: A primer}},
  journal = {Neurology. Genetics},
  year    = {2019},
  doi     = {10.1212/nxg.0000000000000323},
  pmid    = {31119194},
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}

@article{cao2019-30890471,
  author  = {Cao, Jiqing and Zhong, Margaret B and Toro, Carlos A and Zhang, Larry and Cai, Dongming},
  title   = {{Endo-lysosomal pathway and ubiquitin-proteasome system dysfunction in Alzheimer's disease pathogenesis}},
  journal = {Neuroscience letters},
  year    = {2019},
  doi     = {10.1016/j.neulet.2019.03.016},
  pmid    = {30890471},
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}

@article{mondal2019-30844238,
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  title   = {{Protein Arginine Deiminases (PADs): Biochemistry and Chemical Biology of Protein Citrullination}},
  journal = {Accounts of Chemical Research},
  year    = {2019},
  doi     = {10.1021/acs.accounts.9b00024},
  pmid    = {30844238},
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}

@article{oikawa2019-30823664,
  author  = {Oikawa, Naoto and Walter, Jochen},
  title   = {{Presenilins and γ-Secretase in Membrane Proteostasis}},
  journal = {Cells},
  year    = {2019},
  doi     = {10.3390/cells8030209},
  pmid    = {30823664},
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}

@article{dong2018-30577555,
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  title   = {{The Autophagy-Lysosomal Pathways and Their Emerging Roles in Modulating Proteostasis in Tumors}},
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  pmid    = {30577555},
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@article{laskowska2019-30529741,
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  title   = {{Proteomic analysis of protein homeostasis and aggregation}},
  journal = {Journal of proteomics},
  year    = {2019},
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  pmid    = {30529741},
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@article{silva2019-30442948,
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  title   = {{Dysregulation of autophagy and stress granule-related proteins in stress-driven Tau pathology}},
  journal = {Cell death and differentiation},
  year    = {2019},
  doi     = {10.1038/s41418-018-0217-1},
  pmid    = {30442948},
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@article{samant2018-30429547,
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  title   = {{Distinct proteostasis circuits cooperate in nuclear and cytoplasmic protein quality control}},
  journal = {Nature},
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@article{devi2018-30374284,
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  title   = {{Fighting the Cause of Alzheimer's and GNE Myopathy}},
  journal = {Frontiers in neuroscience},
  year    = {2018},
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@article{kurtishi2019-30182337,
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  year    = {2019},
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@article{lichtenthaler2018-29976761,
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@article{stoffel2018-29725009,
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  title   = {{SMPD3 deficiency perturbs neuronal proteostasis and causes progressive cognitive impairment}},
  journal = {Cell death \& disease},
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@article{fricker2018-29488822,
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@article{press2019-29580826,
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  title   = {{Protein aggregates and proteostasis in aging: Amylin and β-cell function}},
  journal = {Mechanisms of ageing and development},
  year    = {2019},
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  pmid    = {29580826},
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@article{nguyen2018-29511098,
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  title   = {{Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay}},
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  year    = {2018},
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  pmid    = {29511098},
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@article{luna2018-29502200,
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  title   = {{Differential α-synuclein expression contributes to selective vulnerability of hippocampal neuron subpopulations to fibril-induced toxicity}},
  journal = {Acta neuropathologica},
  year    = {2018},
  doi     = {10.1007/s00401-018-1829-8},
  pmid    = {29502200},
  url     = {https://doi.org/10.1007/s00401-018-1829-8}
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@article{nonaka2018-28108532,
  author  = {Nonaka, Takashi and Hasegawa, Masato},
  title   = {{TDP-43 Prions}},
  journal = {Cold Spring Harbor perspectives in medicine},
  year    = {2018},
  doi     = {10.1101/cshperspect.a024463},
  pmid    = {28108532},
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@article{tehran2018-29316491,
  author  = {Tehran, Domenico Azarnia and Kuijpers, Marijn and Haucke, Volker},
  title   = {{Presynaptic endocytic factors in autophagy and neurodegeneration}},
  journal = {Current opinion in neurobiology},
  year    = {2018},
  doi     = {10.1016/j.conb.2017.12.018},
  pmid    = {29316491},
  url     = {https://doi.org/10.1016/j.conb.2017.12.018}
}

@article{mochizuki2018-29305061,
  author  = {Mochizuki, Hideki and Choong, Chi-Jing and Masliah, Eliezer},
  title   = {{A refined concept: α-synuclein dysregulation disease}},
  journal = {Neurochemistry international},
  year    = {2018},
  doi     = {10.1016/j.neuint.2017.12.011},
  pmid    = {29305061},
  url     = {https://doi.org/10.1016/j.neuint.2017.12.011}
}

@article{klaips2018-29127110,
  author  = {Klaips, C. L. and Jayaraj, G. G. and Hartl, F. U.},
  title   = {{Pathways of cellular proteostasis in aging and disease}},
  journal = {The Journal of cell biology},
  year    = {2018},
  doi     = {10.1083/jcb.201709072},
  pmid    = {29127110},
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}

@article{spillantini2018-29119326,
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  title   = {{Neurodegeneration and the ordered assembly of α-synuclein}},
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  year    = {2018},
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  pmid    = {29119326},
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@article{miguelezrodriguez2018-29097599,
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  title   = {{Brains with sporadic Creutzfeldt-Jakob disease and copathology showed a prolonged end-stage of disease}},
  journal = {Journal of clinical pathology},
  year    = {2018},
  doi     = {10.1136/jclinpath-2017-204794},
  pmid    = {29097599},
  url     = {https://doi.org/10.1136/jclinpath-2017-204794}
}

@article{penke2017-28994715,
  author  = {Penke, Botond and Bogár, Ferenc and Fülöp, Lívia},
  title   = {{β-Amyloid and the Pathomechanisms of Alzheimer's Disease: A Comprehensive View}},
  journal = {Molecules (Basel, Switzerland)},
  year    = {2017},
  doi     = {10.3390/molecules22101692},
  pmid    = {28994715},
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}

@article{feng2017-28796567,
  author  = {Feng, Yuchen and Klionsky, Daniel J},
  title   = {{Receptors make the pathway choice for protein degradation}},
  journal = {Autophagy},
  year    = {2017},
  doi     = {10.1080/15548627.2017.1356553},
  pmid    = {28796567},
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}

@article{rodolfo2018-28797885,
  author  = {Rodolfo, Carlo and Campello, Silvia and Cecconi, Francesco},
  title   = {{Mitophagy in neurodegenerative diseases}},
  journal = {Neurochemistry international},
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