% alzhub.org topic: placebo-controlled
% Source: https://alzhub.org/topic/placebo-controlled
% 804 entries, in the order the page lists them. Built from alzhub.org's own records.
% 8 entries have no readable author in the source record and carry no author field.

@article{fleisher2026-42441396,
  author  = {Fleisher, Adam S and Munsie, Leanne and Mancini, Michele and Cheng, Yun-Ju and Guo, Jiaying and Nuthall, Hugh and Otero, Diana Svaldi and Kotari, Vikas and others},
  title   = {{Ceperognastat in Early Symptomatic Alzheimer Disease: A Randomized Clinical Trial}},
  journal = {JAMA},
  year    = {2026},
  doi     = {10.1001/jama.2026.12768},
  pmid    = {42441396},
  url     = {https://doi.org/10.1001/jama.2026.12768}
}

@article{ma2026-a6a56bb0,
  author  = {Ma, P. and Zhou, J. and Cheng, Y. and McGeary, J. E. and Taveira, T. H. and Ahmed, A. and Wu, W.-C. and Zamrini and others},
  title   = {{Varenicline as a Repurposable Drug Candidate for ADRD Prevention}},
  journal = {medRxiv (preprint)},
  year    = {2026},
  doi     = {10.64898/2026.09.17.26363232},
  url     = {https://doi.org/10.64898/2026.09.17.26363232}
}

@article{tiwari2026-334d2e2d,
  author  = {Tiwari, A. and Chen, R. and Tan, Y. and Yan, Y. and Wen, Z. and Wei, W.-Q. and Zhong, X. and Li and others},
  title   = {{Antihypertensive Medication Class and Incident Alzheimers Disease and Related Dementias: External Replication Across Two Independent Healthcare Data Sources-the Vanderbilt EHR Synthetic Derivative and US Medicare Claims}},
  journal = {medRxiv (preprint)},
  year    = {2026},
  doi     = {10.64898/2026.09.11.26362859},
  url     = {https://doi.org/10.64898/2026.09.11.26362859}
}

@article{lopezlarraz2026-5e962d7a,
  author  = {Lopez-Larraz, E. and Oriol, D. and Fierro, G. and Jubera-Garcia, E. and Klinzing, J. G. and Sierra-Torralba, M. and Horna-Prat, E. and Escolano and others},
  title   = {{One night of closed-loop auditory stimulation during sleep enhances memory consolidation in patients with Alzheimer's Disease}},
  journal = {medRxiv (preprint)},
  year    = {2026},
  doi     = {10.64898/2026.09.14.26360893},
  url     = {https://doi.org/10.64898/2026.09.14.26360893}
}

@article{rotela2026-cf778e0b,
  author  = {Rotela, Lorena Guadalupe Delvalle and Olmedo, Katherinne Ailen Sanchez},
  title   = {{Eficacia del lecanemab en el tratamiento de la Enfermedad de Alzheimer: revisión de la literatura (2015-2025)}},
  journal = {Zenodo (CERN European Organization for Nuclear Research)},
  year    = {2026},
  doi     = {10.5281/zenodo.22756412},
  url     = {https://doi.org/10.5281/zenodo.22756412}
}

@article{rafieirezvani2026-50b7bf22,
  author  = {Rafiei Rezvani, F. and Azimi, D. and Nekouei, A. H. and Kim, H. and Sauer, C. C. and Wharton, W. and Qiu, D. and Goldstein and others},
  title   = {{Feasibility, Safety, and Preliminary Efficacy of Partnered Rhythmic Rehabilitation in Prodromal Alzheimer's Disease: A 12-Month Pilot Randomized Controlled Trial}},
  journal = {medRxiv (preprint)},
  year    = {2026},
  doi     = {10.64898/2026.09.11.26362767},
  url     = {https://doi.org/10.64898/2026.09.11.26362767}
}

@article{demr2026-42784125,
  author  = {Demır, Ülkü Figen and Dilbaz, Fatmanur Karakuş},
  title   = {{Anti-Amyloid Monoclonal Antibodies in Early Alzheimer Disease: Lecanemab and Donanemab}},
  journal = {Neurology International},
  year    = {2026},
  doi     = {10.3390/neurolint18090171},
  pmid    = {42784125},
  url     = {https://doi.org/10.3390/neurolint18090171}
}

@article{kuik2026-fb8d9249,
  author  = {Kuik, E. J. and Baena-Tan, C. and Moriguchi, S. and Braga, J. and Miler, L. and Rusjan, P. and Bagby, M. and Husain and others},
  title   = {{Effects of sex, treatment resistance, and antidepressant treatment on monoamine oxidase B total distribution volume}},
  journal = {medRxiv (preprint)},
  year    = {2026},
  doi     = {10.64898/2026.09.08.26362462},
  url     = {https://doi.org/10.64898/2026.09.08.26362462}
}

@article{bombonalban2026-7db0e4e9,
  author  = {Bombón-Albán, Paulina Elizabeth},
  title   = {{Terapia anti β-amiloide y enfermedad cerebrovascular: nuevos retos para la neurología vascular}},
  journal = {Acta neurológica colombiana},
  year    = {2026},
  doi     = {10.22379/anc.2188},
  url     = {https://doi.org/10.22379/anc.2188}
}

@article{wang2026-de659fd9,
  author  = {Wang, C. and Woods, C. and Nguyen, T. and Liu, J. and Lin, A.-L. and Cheng, J.},
  title   = {{Multimodal Transformer Modeling of Rapamycin Treatment in Alzheimer's Disease via Random Forest Feature Filtering}},
  journal = {medRxiv (preprint)},
  year    = {2026},
  doi     = {10.64898/2026.08.22.26361114},
  url     = {https://doi.org/10.64898/2026.08.22.26361114}
}

@article{taylor2026-9c23dcf2,
  author  = {Taylor, J. and Alam, J. J. and Gomperts, S. N. and Honig, L. S. and Prins, N. D. and Koubiyr, I. and Chu, H. and Gardner, A. and others},
  title   = {{A Phase 2b randomized clinical trial of the oral p38α inhibitor neflamapimod in dementia with Lewy bodies (DLB)}},
  journal = {Research Square},
  year    = {2026},
  doi     = {10.21203/rs.3.rs-10623740/v1},
  url     = {https://doi.org/10.21203/rs.3.rs-10623740/v1}
}

@article{liu2026-42746606,
  author  = {Liu, Andy and Moghadam, Alexander A. and Alam, Mohammad Samsul and Lutz, Michael William and Navarra, Amber and Luo, Sheng and Wang, Li and Petrella, Jeffrey R. and others},
  title   = {{Clinical Practice Outcomes With Lecanemab for Alzheimer Disease}},
  journal = {Neurology Open Access},
  year    = {2026},
  doi     = {10.1212/wn9.0000000000000121},
  pmid    = {42746606},
  url     = {https://doi.org/10.1212/wn9.0000000000000121}
}

@article{bianchi2026-42613673,
  author  = {Bianchi, Federica and Broers, Barbara and Desmeules, Jules Alexandre and Langlois, Angeline and Wampfler, James and Curtin, François and Pautex, Sophie},
  title   = {{A randomised, double-blind, placebo-controlled crossover trial on cannabinoid-based medication for behavioural disorders in old patients with severe dementia: the study results}},
  journal = {Age and ageing},
  year    = {2026},
  doi     = {10.1093/ageing/afag239},
  pmid    = {42613673},
  url     = {https://doi.org/10.1093/ageing/afag239}
}

@article{paliwal2026-42522305,
  author  = {Paliwal, Deepika and Thakur, Aman},
  title   = {{Exploring the Therapeutic Potential of Chalcones in Alzheimer’s Disease: Mechanistic Insights and SAR Perspectives}},
  journal = {Mini-Reviews in Medicinal Chemistry},
  year    = {2026},
  doi     = {10.2174/0113895575457432260717112508},
  pmid    = {42522305},
  url     = {https://doi.org/10.2174/0113895575457432260717112508}
}

@article{hyemin2026-42449395,
  author  = {Hyemin, Jang and Woo, Kim Jae and Won, Hwang Jung and Da Woon, Jeong and Jeongeun, Ka and Da Min, Kang and Hyun, Suh Chong and Yangsean, Choi and others},
  title   = {{Real-world safety and implementation challenges of lecanemab therapy for Alzheimer's disease in South Korea: a single-center experience}},
  journal = {Alzheimer's research \& therapy},
  year    = {2026},
  doi     = {10.1186/s13195-026-02141-1},
  pmid    = {42449395},
  url     = {https://doi.org/10.1186/s13195-026-02141-1}
}

@article{noh2026-42676462,
  author  = {Noh, M. Y. and Sung, W. and Kim, H. and Son, B. and Kim, Y. E. and Choi, Y. Y. and Holtzman, D. M. and Kim, S. H.},
  title   = {{Lecanemab in symptomatic PSEN1 p.Met233Val early-onset Alzheimer's disease: Neuroimaging safety, regional amyloid-PET dynamics, and longitudinal plasma biomarkers}},
  journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)},
  year    = {2026},
  doi     = {10.1002/dad2.70468},
  pmid    = {42676462},
  url     = {https://doi.org/10.1002/dad2.70468}
}

@article{chauhan2026-a7800f34,
  author  = {Chauhan, Ankush and Paliwal, Deepika and Thakur, Aman and Kaushik, Niranjan and Sahu, Rakesh and Jha, Avinash and Chaudhary, Hashim},
  title   = {{Triazole Hybrids for Alzheimer's Disease: Multitarget Potential and SAR Insights}},
  journal = {ChemistrySelect},
  year    = {2026},
  doi     = {10.1002/slct.73763},
  url     = {https://doi.org/10.1002/slct.73763}
}

@article{bhati2026-0a449f11,
  author  = {Bhati, Sampat Singh and Tanwar, Sampat Singh},
  title   = {{Therapeutic monoclonal antibodies targeting amyloid beta in Alzheimer disease current evidence clinical outcomes limitations and future directions}},
  journal = {Discover Neuroscience},
  year    = {2026},
  doi     = {10.1186/s13064-026-00295-0},
  url     = {https://doi.org/10.1186/s13064-026-00295-0}
}

@article{weiss2026-42373113,
  author  = {Weiss, Sophie M. and Watt, Jennifer A. and Ewa, Vivian and Straus, Sharon Elizabeth},
  title   = {{Lecanemab use for early Alzheimer disease in Canada}},
  journal = {Canadian Medical Association Journal},
  year    = {2026},
  doi     = {10.1503/cmaj.260193},
  pmid    = {42373113},
  url     = {https://doi.org/10.1503/cmaj.260193}
}

@article{bertram2026-42286243,
  author  = {Bertram, David and Ophey, Anja and Röttgen, Sinah and Kufer, Konstantin and Merten, Nele and Fink, Gereon R. and Kalbe, Elke and Hansen, Clint and others},
  title   = {{ActiTect: a generalizable machine learning pipeline for REM sleep behavior disorder screening through standardized actigraphy}},
  journal = {npj Digital Medicine},
  year    = {2026},
  doi     = {10.1038/s41746-026-02738-8},
  pmid    = {42286243},
  url     = {https://doi.org/10.1038/s41746-026-02738-8}
}

@article{sha2026-42368154,
  author  = {Sha, Jiaojiao and Geng, Zijin and Qi, Shanyu and Du, Liangjia and Hu, Qianqian and Cai, Minqi and Chen, Dezhu and Chen, Yuehua and others},
  title   = {{Characterization of the Anti-Alzheimer Drug Lecanemab by Mass Spectrometry}},
  journal = {ACS Omega},
  year    = {2026},
  doi     = {10.1021/acsomega.6c02666},
  pmid    = {42368154},
  url     = {https://doi.org/10.1021/acsomega.6c02666}
}

@article{kordi2026-42634764,
  author  = {Kordi, Mohammad Reza and Kooshan, Amir Reza and Jafari-Hokmabadi, Seyed Pouya and Gaeini, Abbas Ali and Zobeydi, Amir Mohammad},
  title   = {{Combating cognitive decline in a rat model of Alzheimer’s disease: The role of high-intensity interval training and cannabidiol administration in modulating microRNA-124, BACE1, and nestin}},
  journal = {Current Journal of Neurology},
  year    = {2026},
  doi     = {10.18502/cjn.v24i3.21601},
  pmid    = {42634764},
  url     = {https://doi.org/10.18502/cjn.v24i3.21601}
}

@article{ruthirakuhan2026-42178577,
  author  = {Ruthirakuhan, M. and Mills, M. and Rosenberg, P. and Haughey, N. and Mintzer, J. and Brawman-Mintzer, O. and Craft, S. and Herrmann, N. and others},
  title   = {{Uncovering lipid biomarkers linked to methylphenidate efficacy in treating apathy in Alzheimer's disease: insights from the ADMET 2 trial}},
  journal = {Alzheimer's research \& therapy},
  year    = {2026},
  doi     = {10.1186/s13195-026-02055-y},
  pmid    = {42178577},
  url     = {https://doi.org/10.1186/s13195-026-02055-y}
}

@article{atri2026-42128444,
  author  = {Atri, A. and Apostolova, L. G. and Iwata, A. and Wessels, A. M. and Atkins, A. and Lu, M. and Ye, W. and Ryan, S. and Doty, E. G.},
  title   = {{Clinical Meaningfulness of Donanemab in Early Symptomatic Alzheimer Disease: Data From the Randomized Phase 3 TRAILBLAZER-ALZ 2 Trial}},
  journal = {Neurology: Clinical Practice},
  year    = {2026},
  doi     = {10.1212/CPJ.0000000000200621},
  pmid    = {42128444},
  url     = {https://doi.org/10.1212/CPJ.0000000000200621}
}

@article{igarashi2026-42108615,
  author  = {Igarashi, A. and Azuma-Kasai, M. and Tani, M. and Utsumi, T. and Shibahara, H. and Inoue, S. and Rothwell, S. and Kamanaka, G. and Sakata, Y. and Hiyoshi, H. and Tomita, K.},
  title   = {{The social value of lecanemab for patients with early Alzheimer's disease in Japan}},
  journal = {Journal of Alzheimer's Disease},
  year    = {2026},
  doi     = {10.1177/13872877261447312},
  pmid    = {42108615},
  url     = {https://doi.org/10.1177/13872877261447312}
}

@article{hafez2026-42084750,
  author  = {Hafez, Mohamed Mahmoud and Abbas, Haidy A. and Shoman, Nabil A. and Soubh, Ayman A. and Aly, Omnia and Sallam, Mohamed F. and Seliem, Mahmoud A. and Malaak, Fady A.},
  title   = {{A new era in neuropharmacology: assessing the efficacy and safety of novel anti-amyloid and non-amyloid drug targets for Alzheimer's disease}},
  journal = {Journal of Neurology},
  year    = {2026},
  doi     = {10.1007/s00415-026-13829-7},
  pmid    = {42084750},
  url     = {https://doi.org/10.1007/s00415-026-13829-7}
}

@article{hopkinson2026-42302797,
  author  = {Hopkinson, Olivia K and Chobanov, Jan and Goordeen, Darshna and Man, Kenneth K C and Wong, Ian C K and Reeve, Emily and Bell, J Simon and Wei, Li and others},
  title   = {{Abrupt discontinuation and tapering of antipsychotics in older adults with dementia: a target trial emulation study}},
  journal = {The lancet. Healthy longevity},
  year    = {2026},
  doi     = {10.1016/j.lanhl.2026.100852},
  pmid    = {42302797},
  url     = {https://doi.org/10.1016/j.lanhl.2026.100852}
}

@article{meng2026-42108759,
  author  = {Meng, Qingfu and Li, Jianning and Xu, Gaungxu and Zhang, Wei and Cao, Rong and Cai, Keshu},
  title   = {{Ginsenoside Rh2 Alleviates Alzheimer Disease Models via Effects on Ferroptosis‐Related Neuroinflammation}},
  journal = {Journal of Biochemical and Molecular Toxicology},
  year    = {2026},
  doi     = {10.1002/jbt.70860},
  pmid    = {42108759},
  url     = {https://doi.org/10.1002/jbt.70860}
}

@article{rahbek2026-42050692,
  author  = {Rahbek, Martin Torp and Kildegaard, Helene and Hallas, Jesper and Ernst, Martin and Lund, Lars Christian},
  title   = {{Acetylcholinesterase inhibitors and the risk of delirium – a Danish nationwide register-based cohort study}},
  journal = {Alzheimer s Research \& Therapy},
  year    = {2026},
  doi     = {10.1186/s13195-026-02060-1},
  pmid    = {42050692},
  url     = {https://doi.org/10.1186/s13195-026-02060-1}
}

@article{asano2026-42033242,
  author  = {Asano, Tomoaki and Izumi, Kana and Ishikawa, Takashi},
  title   = {{Large-Screen Group Digital Reminiscence Therapy Reduces BPSD in Dementia: Findings from a Crossover Comparative Study}},
  journal = {Clinical Gerontologist},
  year    = {2026},
  doi     = {10.1080/07317115.2026.2664051},
  pmid    = {42033242},
  url     = {https://doi.org/10.1080/07317115.2026.2664051}
}

@article{nonino2026-41985900,
  author  = {Nonino, F. and Minozzi, S. and Sambati, L. and Del Giovane, C. and Baldin, E. and Bassi, M. C. and others},
  title   = {{Amyloid-beta-targeting monoclonal antibodies for people with mild cognitive impairment or mild dementia due to Alzheimer's disease (Cochrane review)}},
  journal = {Cochrane Database of Systematic Reviews},
  year    = {2026},
  doi     = {10.1002/14651858.CD016297},
  pmid    = {41985900},
  url     = {https://doi.org/10.1002/14651858.CD016297}
}

@article{study2026-b85e6325,
  title   = {{Bildgebungsanomalien bei Alzheimer-Therapie mit Lecanemab}},
  journal = {Neuroradiologie Scan},
  year    = {2026},
  doi     = {10.1055/a-2788-0873},
  url     = {https://doi.org/10.1055/a-2788-0873}
}

@article{gao2026-42015793,
  author  = {Gao, Lan and Watson, Rosie and Yassi, Nawaf},
  title   = {{Cost-Effectiveness of Donanemab for Early Alzheimer Disease in Australia}},
  journal = {The Medical journal of Australia},
  year    = {2026},
  doi     = {10.5694/mja2.70186},
  pmid    = {42015793},
  url     = {https://doi.org/10.5694/mja2.70186}
}

@article{gao2026-91bcd677,
  author  = {Gao, Lan and Watson, R and Yassi, Nawaf},
  title   = {{Cost-Effectiveness of Donanemab for Early Alzheimer Disease in Australia}},
  journal = {Deakin Research Online (Deakin University)},
  year    = {2026},
  doi     = {10.26187/deakin.32142121},
  url     = {https://doi.org/10.26187/deakin.32142121}
}

@article{cummings2026-41865758,
  author  = {Cummings, Jeffrey L and Atri, Alireza and Sano, Mary and Zetterberg, Henrik and Scheltens, Philip and Knop, Filip K and Johannsen, Peter and Wichmann, Christian Ahmad and others},
  title   = {{Efficacy and safety of oral semaglutide 14 mg (flexible dose) in early-stage symptomatic Alzheimer's disease (evoke and evoke+): two phase 3, randomised, placebo-controlled trials}},
  journal = {The Lancet},
  year    = {2026},
  doi     = {10.1016/s0140-6736(26)00459-9},
  pmid    = {41865758},
  url     = {https://doi.org/10.1016/s0140-6736(26)00459-9}
}

@article{qu2026-41907844,
  author  = {Qu, G. and Bi, Y. and Wang, L. and Xu, L. and Zhang, Y. and Ma, Y. and Tian, C. and Zhang, Z.},
  title   = {{Efficacy of Dang Gui Shao Yao San in treating vascular dementia in animal models: a systematic review and meta-analysis}},
  journal = {Frontiers in aging neuroscience},
  year    = {2026},
  doi     = {10.3389/fnagi.2026.1701536},
  pmid    = {41907844},
  url     = {https://doi.org/10.3389/fnagi.2026.1701536}
}

@article{dwivedi2026-41740144,
  author  = {Dwivedi, A. and Anjali, A. and Narzari, H. and Kumar, Y. and Sharma, H. P. and Dubey, A. and Nilima, N. and Rajan, R. and others},
  title   = {{Efficacy of Bacopa monnieri (Linn.) on Cognitive Function and Alterations in Blood Metabolites in Patients With Amnestic Mild Cognitive Impairment and Early Alzheimer Disease: Protocol for an Exploratory Double-Blind, Randomized, Placebo-Controlled Trial}},
  journal = {JMIR research protocols},
  year    = {2026},
  doi     = {10.2196/82891},
  pmid    = {41740144},
  url     = {https://doi.org/10.2196/82891}
}

@article{simon2026-41732331,
  author  = {Simon, Lecerf and Octave, Guinebretiere and Raphaël, Bentegeac and Victoria, Gauthier and Estelle, Aymes and Chaymae, Mekkaoui and Julien, Dumurgier and Philippe, Amouyel and others},
  title   = {{Long-term effect of discontinuing anticholinesterase treatment on cognitive decline and mortality in Alzheimer's disease in France: a quasi-experiment and target trial emulation study}},
  journal = {The Lancet regional health. Europe},
  year    = {2026},
  doi     = {10.1016/j.lanepe.2026.101607},
  pmid    = {41732331},
  url     = {https://doi.org/10.1016/j.lanepe.2026.101607}
}

@article{stroud2026-41689409,
  author  = {Stroud, Jared and Cummings, Jeffrey L. and Chumki, Sanjeda R and Such, Pedro and Wang, David and Palma, Anton M. and Zhang, Z. and Grossberg, George Thomas},
  title   = {{Brexpiprazole for treating agitation in different groups of people with Alzheimer’s dementia: a plain language summary}},
  journal = {Neurodegenerative Disease Management},
  year    = {2026},
  doi     = {10.1080/17582024.2026.2623968},
  pmid    = {41689409},
  url     = {https://doi.org/10.1080/17582024.2026.2623968}
}

@article{lee2026-41697144,
  author  = {Lee, Wen-Teng and Jing Tong, W. A. N. G. and Tsai, Ming‐Hsien and Fang, Yu‐Wei},
  title   = {{GLP-1 receptor agonists reduce dementia and Alzheimer disease risk in diabetic patients with CKD}},
  journal = {Nephrology Dialysis Transplantation},
  year    = {2026},
  doi     = {10.1093/ndt/gfag032},
  pmid    = {41697144},
  url     = {https://doi.org/10.1093/ndt/gfag032}
}

@article{pol2026-af9354a9,
  author  = {Pol, Rahul P. and Purane, Laxmikant Maruti and Kane, S. R. and Misal, A. A. and Yadav, Akshay R. and Chopade, Atul R. and Sarvagod, S.M. and Jadhav, P. D.},
  title   = {{Multifunctional Tannins from Phyllanthus amarus Exhibit Disease-Modifying Activities Against Alzheimer's Pathogenesis: An In Vitro and In Vivo Investigation}},
  journal = {IJPAR JOURNAL},
  year    = {2026},
  doi     = {10.61096/ijpar.v15.iss1.2026.80-94},
  url     = {https://doi.org/10.61096/ijpar.v15.iss1.2026.80-94}
}

@article{devanand2026-41405855,
  author  = {Devanand, D P and Wisniewski, Thomas and Razlighi, Qolamreza and Qian, Min and Wei, Renjie and Andrews, Howard F and Acosta, Edward P and Bell, Karen L and others},
  title   = {{Valacyclovir Treatment of Early Symptomatic Alzheimer Disease: The VALAD Randomized Clinical Trial}},
  journal = {JAMA},
  year    = {2026},
  doi     = {10.1001/jama.2025.21738},
  pmid    = {41405855},
  url     = {https://doi.org/10.1001/jama.2025.21738}
}

@article{vanderlip2026-41653883,
  author  = {Vanderlip, C. R. and Gillen, D. L. and Grill, J. D. and Stark, C. E. L.},
  title   = {{Digital memory assessments and plasma pTau217 enable efficient preclinical Alzheimer's trials}},
  journal = {The journal of prevention of Alzheimer's disease},
  year    = {2026},
  doi     = {10.1016/j.tjpad.2026.100503},
  pmid    = {41653883},
  url     = {https://doi.org/10.1016/j.tjpad.2026.100503}
}

@article{wieland2026-41641880,
  author  = {Wieland, Lisa S and Ludeman, Emilie and Chi, Yuan and Feinberg, Termeh M and Chen, I-Hui and Chen, Kee-Hsin and Zhu, Yanan and Wolverson, Emma and others},
  title   = {{Ginkgo biloba for cognitive impairment and dementia}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2026},
  doi     = {10.1002/14651858.CD013661.pub2},
  pmid    = {41641880},
  url     = {https://doi.org/10.1002/14651858.CD013661.pub2}
}

@article{sarwade2026-69c35085,
  author  = {Sarwade1, Prakash and Gaisamudre*2, Kavita and Sonwani3, Kalpana and Jasra4, Khushboo and Rawat5, Khushi and Saha6, Purabi and Kumar7, Roshan},
  title   = {{Aldehyde-Mediated Neurotoxicity and Lutein Intervention: A Novel Therapeutic Strategy for Alzheimer's Disease}},
  journal = {Zenodo (CERN European Organization for Nuclear Research)},
  year    = {2026},
  doi     = {10.5281/zenodo.18298037},
  url     = {https://doi.org/10.5281/zenodo.18298037}
}

@article{sarwade2026-9ce011bf,
  author  = {Sarwade1, Prakash and Gaisamudre*2, Kavita and Sonwani3, Kalpana and Jasra4, Khushboo and Rawat5, Khushi and Saha6, Purabi and Kumar7, Roshan},
  title   = {{Aldehyde-Mediated Neurotoxicity and Lutein Intervention: A Novel Therapeutic Strategy for Alzheimer's Disease}},
  journal = {Zenodo (CERN European Organization for Nuclear Research)},
  year    = {2026},
  doi     = {10.5281/zenodo.18298036},
  url     = {https://doi.org/10.5281/zenodo.18298036}
}

@article{heo2026-41527747,
  author  = {Heo, Rachel J. and Negida, Ahmed and Barrett, Matthew J. and Chrenka, Ella A. B. and Bayram, Ece and Kane, Joseph P. M. and Werner, Ann M. and Rossom, Rebecca C. and others},
  title   = {{Cholinesterase inhibitors for patients with dementia: Patterns of prescribing and disparities in treatment}},
  journal = {Journal of Alzheimer s Disease},
  year    = {2026},
  doi     = {10.1177/13872877251411418},
  pmid    = {41527747},
  url     = {https://doi.org/10.1177/13872877251411418}
}

@article{kanika2026-329f85f8,
  author  = {Kanika, Pasrija and Patel, Alka and Tripathy, Bichitrananda},
  title   = {{Curcuma longa-Derived Curcumin Nanoparticles in Experimental Models of Alzheimer’s Disease: A Formulation-Based Approach}},
  journal = {Probecell Science},
  year    = {2026},
  doi     = {10.65807/prob.sci.2025.2.2.4},
  url     = {https://doi.org/10.65807/prob.sci.2025.2.2.4}
}

@article{mao2026-41520099,
  author  = {Mao, Chenhui and Wang, Wenjun and Huang, Xinying and Wu, Meiqi and Wang, Yifei and Wang, Tianyi and Qiu, Yuyue and Chu, Shanshan and others},
  title   = {{Real world clinical practice of lecanemab at PUMCH dementia cohort: focus on dynamic imaging and biomarker evolution}},
  journal = {Alzheimer s Research \& Therapy},
  year    = {2026},
  doi     = {10.1186/s13195-025-01943-z},
  pmid    = {41520099},
  url     = {https://doi.org/10.1186/s13195-025-01943-z}
}

@article{tyagi2026-41510854,
  author  = {Tyagi, S. and Murali, N. and Singh, S. K. and Babtiwale, SR. and Padhi, B. K. and Lakshmi, N. R. A. and Gandhi, A. P.},
  title   = {{A Systematic Review to Evaluate the Effect of Neflamapimod on Cognitive Function and Progression of Dementia}},
  journal = {Neurology India},
  year    = {2026},
  doi     = {10.4103/neurol-india.neurol-india-d-25-00227},
  pmid    = {41510854},
  url     = {https://doi.org/10.4103/neurol-india.neurol-india-d-25-00227}
}

@article{vangils2026-41508135,
  author  = {van Gils, Veerle and Waterink, Lisa and Wimmers, S. C. P. M. and Jelsma, J.G.M. and de Vugt, Marjolein Elizabeth and Handels, Ron L. H. and Sikkes, Sietske A.M. and van der Flier, Wiesje M. and others},
  title   = {{The Lifestyle Intervention in memory clinics of General and academic Hospitals Trial (LIGHT): Rationale and study design of a randomized controlled trial to reduce modifiable dementia risk}},
  journal = {Alzheimer s Research \& Therapy},
  year    = {2026},
  doi     = {10.1186/s13195-025-01947-9},
  pmid    = {41508135},
  url     = {https://doi.org/10.1186/s13195-025-01947-9}
}

@article{kupiec2026-41500915,
  author  = {Kupiec, J. W. and Porsteinsson, A. P. and Turner, R. S. and Hendrix, S. and Mallinckrodt, C. and Khan, A. and Cohen, I. and Liss, J. and others},
  title   = {{Phase 3 randomized clinical trials of simufilam in mild-to-moderate Alzheimer's disease}},
  journal = {The journal of prevention of Alzheimer's disease},
  year    = {2026},
  doi     = {10.1016/j.tjpad.2025.100469},
  pmid    = {41500915},
  url     = {https://doi.org/10.1016/j.tjpad.2025.100469}
}

@article{kalita2026-41482856,
  author  = {Kalita, Rupsikha and Sarma, Anupam and Baruah, Himakshi and Zaman, Asifa and Goswami, Deepjyoti},
  title   = {{Nose to Brain Delivery of Curcumin Loaded Therapeutic Nanostructures for Neurodegenerative Diseases}},
  journal = {Biopharmaceutics \& Drug Disposition},
  year    = {2026},
  doi     = {10.1002/bdd.70021},
  pmid    = {41482856},
  url     = {https://doi.org/10.1002/bdd.70021}
}

@article{cummings2026-c800c391,
  author  = {Cummings, J. L. and Atri, A. and Scheltens, P. and others},
  title   = {{Efficacy and safety of oral semaglutide 14 mg (flexible dose) in early-stage symptomatic Alzheimer's disease (EVOKE and EVOKE+): two phase 3, randomised, placebo-controlled trials}},
  journal = {The Lancet},
  year    = {2026},
  doi     = {10.1016/s0140-6736(26)00459-9},
  pmid    = {41865758},
  url     = {https://doi.org/10.1016/s0140-6736(26)00459-9}
}

@article{dinnerstein2026-41773886,
  author  = {Dinnerstein, Eric},
  title   = {{Lecanemab and Donanemab Combination Therapy for Alzheimer’s Disease-The Cocktail May Work Even Better Together}},
  journal = {Alzheimer Disease \& Associated Disorders},
  year    = {2026},
  doi     = {10.1097/wad.0000000000000711},
  pmid    = {41773886},
  url     = {https://doi.org/10.1097/wad.0000000000000711}
}

@article{sankhe2026-41521126,
  author  = {Sankhe, Krushnaa and Ruthirakuhan, Myuri T. and Andreazza, Ana C. and Brawman‐Mintzer, Olga and Craft, Suzanne and Herrmann, Nathan and Ismail, Zahinoor and Lerner, Alan J. and others},
  title   = {{Peripheral biomarkers associated with apathy and predicting response to methylphenidate: Secondary analysis of the Apathy in Dementia Methylphenidate Trial 2 (ADMET2) study}},
  journal = {International Psychogeriatrics},
  year    = {2026},
  doi     = {10.1016/j.inpsyc.2025.100181},
  pmid    = {41521126},
  url     = {https://doi.org/10.1016/j.inpsyc.2025.100181}
}

@article{bellversanchis2026-41445192,
  author  = {Bellver-Sanchis, A. and Valle-Garcia, D. and Barbaraci, C. and Romero-Becerra, F. and Singh, R. K. and Jarne-Ferrer, J. and Vasilopoulou, F. and Irisarri, A. and others},
  title   = {{First-in-class SAM-competitive G9a inhibitor FLAV-27 as a disease-modifying therapy for Alzheimer disease}},
  journal = {Molecular therapy : the journal of the American Society of Gene Therapy},
  year    = {2026},
  doi     = {10.1016/j.ymthe.2025.12.038},
  pmid    = {41445192},
  url     = {https://doi.org/10.1016/j.ymthe.2025.12.038}
}

@article{wu2025-41420258,
  author  = {Wu, C. Y. and Alkabbani, W. and Shah, B. R. and Kapral, M. K. and Edwards, J. D. and Maxwell, C. J. and others},
  title   = {{Comparative dementia risk with GLP1 receptor agonists, SGLT2 inhibitors, or DPP4 inhibitors: a population-based cohort study}},
  journal = {Alzheimer's Research \& Therapy},
  year    = {2025},
  doi     = {10.1186/s13195-025-01929-x},
  pmid    = {41420258},
  url     = {https://doi.org/10.1186/s13195-025-01929-x}
}

@article{zuliani2025-41396413,
  author  = {Zuliani, Giovanni and Brombo, Gloria and Romagnoli, Tommaso and Polastri, Michele and Dario, Francesco di Paola and Zuin, Marco},
  title   = {{Effectiveness of acetylcholinesterase inhibitors and memantine in patients affected by severe dementia}},
  journal = {GeroScience},
  year    = {2025},
  doi     = {10.1007/s11357-025-02052-3},
  pmid    = {41396413},
  url     = {https://doi.org/10.1007/s11357-025-02052-3}
}

@article{vandyck2025-41355080,
  author  = {van Dyck, C. H. and Sperling, R. and Johnson, K. and Dhadda, S. and Kanekiyo, M. and Li, D. and Gee, M. and Hersch, S. and Irizarry, M. and Kramer, L.},
  title   = {{Long-term safety and efficacy of lecanemab in early Alzheimer's disease: Results from the Clarity AD open-label extension study}},
  journal = {Alzheimer's \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70905},
  pmid    = {41355080},
  url     = {https://doi.org/10.1002/alz.70905}
}

@article{odonnell2025-42667001,
  author  = {O'Donnell, Alison J and Handler, Steven M and Faieta, Julie and Jump, Robin},
  title   = {{Can Telehealth Improve Access to Amyloid-Targeting Therapies for Veterans Living With Alzheimer Disease?}},
  journal = {Federal Practitioner},
  year    = {2025},
  doi     = {10.12788/fp.0656},
  pmid    = {42667001},
  url     = {https://doi.org/10.12788/fp.0656}
}

@article{shamrok2025-41434629,
  author  = {Shamrok, Hanadi and Davidy, Tal and Yore, Iscka and Niv, Tal and Yaffe, Tali C and Ravona‐Springer, Ramit and Livny, Abigail and Lesman‐Segev, Orit H. and others},
  title   = {{Combination of Intranasal insulin and oral semaglutide for cognition in older adults with metabolic syndrome at high dementia risk}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70860_102127},
  pmid    = {41434629},
  url     = {https://doi.org/10.1002/alz70860_102127}
}

@article{zhou2025-41448821,
  author  = {Zhou, Hedi and Shobo, Adeola and Hancock, Mark A. and El Ansari, Fatima and Touj, Sara and Malvankar, Medhinee M. and Wu, Pei You and Masson, Louis-Charles and others},
  title   = {{Development of a novel anti‐amyloid therapeutic: an orally administrable anti‐abeta‐oligomer compound in early preventative intervention}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70859_101967},
  pmid    = {41448821},
  url     = {https://doi.org/10.1002/alz70859_101967}
}

@article{zimmer2025-41330788,
  author  = {Zimmer, Jennifer A. and Sims, John R. and Evans, Cynthia Duggan and Nery, Emel Serap Monkul and Wang, Hong and Wessels, Alette M. and Tronchin, Giulia and Sato, Shoichiro and others},
  title   = {{Donanemab in early symptomatic Alzheimer’s disease: results from the TRAILBLAZER-ALZ 2 long-term extension}},
  journal = {The Journal of Prevention of Alzheimer s Disease},
  year    = {2025},
  doi     = {10.1016/j.tjpad.2025.100446},
  pmid    = {41330788},
  url     = {https://doi.org/10.1016/j.tjpad.2025.100446}
}

@article{cantoni2025-41359335,
  author  = {Cantoni, V. and Casula, E. P. and Tarantino, B. and Cupidi, C. and Huber, N. and Altomare, D. and Premi, E. and Zummo, E. and others},
  title   = {{Home-Based Gamma Transcranial Alternating Current Stimulation in Patients With Alzheimer Disease: A Randomized Clinical Trial}},
  journal = {JAMA network open},
  year    = {2025},
  doi     = {10.1001/jamanetworkopen.2025.46556},
  pmid    = {41359335},
  url     = {https://doi.org/10.1001/jamanetworkopen.2025.46556}
}

@article{monfared2025-41433980,
  author  = {Monfared, Amir Abbas Tahami and Zhang, Raymond J. and Zhang, Quanwu and Gao, Ran and Haji, Babak},
  title   = {{Lecanemab adoption and geographic variation among patients with diagnosis of mild cognitive impairment or Alzheimer's dementia in Medicare fee‐for‐service beneficiaries}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70860_106870},
  pmid    = {41433980},
  url     = {https://doi.org/10.1002/alz70860_106870}
}

@article{stern2025-41435407,
  author  = {Stern, Andrew M. and Francis, Anna G. and Meunier, Angela L. and Anderson, Amirah K. and Hennessey, Elizabeth L. and Miller, Michael B. and Lemere, Cynthia Ann and Selkoe, Dennis J.},
  title   = {{Lecanemab, aducanumab, and donanemab bind the same human Alzheimer disease Aβ aggregates at different epitopes}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70855_099914},
  pmid    = {41435407},
  url     = {https://doi.org/10.1002/alz70855_099914}
}

@article{wildsmith2025-41447716,
  author  = {Wildsmith, Kristin R. and Charil, Arnaud and Benzinger, Tammie L.S. and Gordon, Brian Andrew and Bhagunde, Pratik R. and Li, David and Wang, Guoqiao and Reyderman, Larisa and others},
  title   = {{Lecanemab in DIAD: 6‐Month Amyloid PET Results from the DIAN‐TU‐001 Trial}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70859_105303},
  pmid    = {41447716},
  url     = {https://doi.org/10.1002/alz70859_105303}
}

@article{edison2025-41326666,
  author  = {Edison, P. and Femminella, G. D. and Ritchie, C. and Nowell, J. and Holmes, C. and Walker, Z. and Ridha, B. and Raza, S. and Livingston, N. R. and Frangou, E. and others},
  title   = {{Liraglutide in mild to moderate Alzheimer's disease: a phase 2b clinical trial}},
  journal = {Nature Medicine},
  year    = {2025},
  doi     = {10.1038/s41591-025-04106-7},
  pmid    = {41326666},
  url     = {https://doi.org/10.1038/s41591-025-04106-7}
}

@article{trushin2025-41450141,
  author  = {Trushin, Sergey A. and Ostroot, Mark A. and Trushina, Eugenia V.},
  title   = {{Partial Mitochondrial Complex I Inhibitors as a Therapy for Alzheimer Disease}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70859_105252},
  pmid    = {41450141},
  url     = {https://doi.org/10.1002/alz70859_105252}
}

@article{galvin2025-41416579,
  author  = {Galvin, James E. and Tolea, Magdalena I. and Scharre, Douglas W. and Hamby, Mary E. and Iaci, Jennifer F. and Grundman, Michael and Caggiano, Anthony O.},
  title   = {{Phase 2 study of zervimesine (CT1812) in participants with mild‐to‐moderate dementia with Lewy bodies (DLB)}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.71004},
  pmid    = {41416579},
  url     = {https://doi.org/10.1002/alz.71004}
}

@article{lu2025-41082199,
  author  = {Lu, M. and Kim, M. J. and Collins, E. C. and Shcherbinin, S. and Ellinwood, A. K. and Yokoi, Y. and Brooks, D. A. and Hansson, O. and others},
  title   = {{Posttreatment Amyloid Levels and Clinical Outcomes Following Donanemab for Early Symptomatic Alzheimer Disease: A Secondary Analysis of the TRAILBLAZER-ALZ 2 Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2025},
  doi     = {10.1001/jamaneurol.2025.3869},
  pmid    = {41082199},
  url     = {https://doi.org/10.1001/jamaneurol.2025.3869}
}

@article{zhou2025-41447712,
  author  = {Zhou, Jin and Andreozzi, Erica M. and Llibre‐Guerra, Jorge J. and Clifford, David B. and Li, David and Wang, Guoqiao and Schneider, Lon S. S. and McDade, Eric and others},
  title   = {{Safety of Lecanemab After 6‐Month Treatment in the DIAN‐TU‐001 Trial}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70859_105304},
  pmid    = {41447712},
  url     = {https://doi.org/10.1002/alz70859_105304}
}

@article{njamnshi2025-41395729,
  author  = {Njamnshi, Wepnyu Yembe and Chiotis, Konstantinos and Tsoy, Elena and Blazhenets, Ganna and Maiti, Piyush and Zhang, Jiaxiuxiu and Allen, Isabel Elaine and Rocha, Salma and others},
  title   = {{Tablet‐based Cognitive Assessment Tool (TabCAT) in a multisite study of early‐onset Alzheimer's disease}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.71012},
  pmid    = {41395729},
  url     = {https://doi.org/10.1002/alz.71012}
}

@article{torresyaghi2025-41286676,
  author  = {Torres-Yaghi, Y. and Chrones, L. and Abler, V. and Brunson, G.},
  title   = {{Safety and efficacy of pimavanserin in patients with Lewy body dementia experiencing dementia-related psychosis in the HARMONY study}},
  journal = {BMC Neurology},
  year    = {2025},
  doi     = {10.1186/s12883-025-04496-8},
  pmid    = {41286676},
  url     = {https://doi.org/10.1186/s12883-025-04496-8}
}

@article{albertini2026-41286448,
  author  = {Albertini, G. and Zielonka, M. and Cuypers, M. L. and Snellinx, A. and Xu, C. and Poovathingal, S. and Wojno, M. and Davie, K. and van Lieshout, V. and Craessaerts, K. and Wolfs, L. and Pasciuto, E. and others},
  title   = {{The Alzheimer's therapeutic Lecanemab attenuates Aβ pathology by inducing an amyloid-clearing program in microglia}},
  journal = {Nature Neuroscience},
  year    = {2026},
  doi     = {10.1038/s41593-025-02125-8},
  pmid    = {41286448},
  url     = {https://doi.org/10.1038/s41593-025-02125-8}
}

@article{roach2025-41275266,
  author  = {Roach, Jared C. and Glusman, Gwênlyn and Rapozo, Molly K. and Merrill, David A. and Bramen, Jennifer E. and Hodes, John F. and Siddarth, Prabha and Meysami, Somayeh and others},
  title   = {{Multidomain therapy for Alzheimer’s disease: a scoping review of cognitive decline trials}},
  journal = {Molecular Neurodegeneration},
  year    = {2025},
  doi     = {10.1186/s13024-025-00912-2},
  pmid    = {41275266},
  url     = {https://doi.org/10.1186/s13024-025-00912-2}
}

@article{xing2025-41322351,
  author  = {Xing, Hang and Hu, Wen-Long and Bao, Sheng-yong},
  title   = {{Acupuncture modulates the microbiota-gut-brain axis: a novel therapeutic strategy for amnestic mild cognitive impairment}},
  journal = {Frontiers in Neuroscience},
  year    = {2025},
  doi     = {10.3389/fnins.2025.1710066},
  pmid    = {41322351},
  url     = {https://doi.org/10.3389/fnins.2025.1710066}
}

@article{rosenberg2025-41350162,
  author  = {Rosenberg, P. B. and Amjad, H. and Burhanullah, H. and Nowrangi, M. and Vandrey, R. and Pierre, M. J. and Outen, J. D. and Schultz, M. and Marano, C. and Agronin, M. and others},
  title   = {{A Randomized Controlled Trial of the Safety and Efficacy of Dronabinol for Agitation in Alzheimer's Disease}},
  journal = {The American Journal of Geriatric Psychiatry},
  year    = {2025},
  doi     = {10.1016/j.jagp.2025.10.011},
  pmid    = {41350162},
  url     = {https://doi.org/10.1016/j.jagp.2025.10.011}
}

@article{li2025-41292493,
  author  = {Li, Yan and Liu, Wenying and Wang, Xuechu and Qin, Wei and Liu, Zhaojun and Lyu, Diyang and Li, Ying and Li, Bingqiu and others},
  title   = {{Effect of SSRIs on clinical progression in amnestic mild cognitive impairment stratified by Alzheimer's disease pathology}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70946},
  pmid    = {41292493},
  url     = {https://doi.org/10.1002/alz.70946}
}

@article{boon2025-41109234,
  author  = {Boon, B. D. C. and Piura, Y. D. and Moloney, C. M. and Chalk, J. L. and Lincoln, S. J. and Rutledge, M. H. and Rothberg, D. M. and Kouri, N. and others},
  title   = {{Neuropathological changes and amyloid-related imaging abnormalities in Alzheimer's disease treated with aducanumab versus untreated: a retrospective case-control study}},
  journal = {The Lancet. Neurology},
  year    = {2025},
  doi     = {10.1016/s1474-4422(25)00313-8},
  pmid    = {41109234},
  url     = {https://doi.org/10.1016/s1474-4422(25)00313-8}
}

@article{sharma2025-08ace6f7,
  author  = {Sharma, Geetika},
  title   = {{Lecanemab, Donanemab, and Emerging Disease Modifying Therapies for Alzheimer Disease: Clinical Evidence and Primary Care Implications in Canada}},
  journal = {International Journal of Science and Research Archive},
  year    = {2025},
  doi     = {10.5281/zenodo.17615266},
  url     = {https://doi.org/10.5281/zenodo.17615266}
}

@article{sharma2025-1b2f6657,
  author  = {Sharma, Geetika},
  title   = {{Lecanemab, Donanemab, and Emerging Disease Modifying Therapies for Alzheimer Disease: Clinical Evidence and Primary Care Implications in Canada}},
  journal = {International Journal of Science and Research Archive},
  year    = {2025},
  doi     = {10.30574/ijsra.2025.17.1.2929},
  url     = {https://doi.org/10.30574/ijsra.2025.17.1.2929}
}

@article{sharma2025-d453d052,
  author  = {Sharma, Geetika},
  title   = {{Lecanemab, Donanemab, and Emerging Disease Modifying Therapies for Alzheimer Disease: Clinical Evidence and Primary Care Implications in Canada}},
  journal = {International Journal of Science and Research Archive},
  year    = {2025},
  doi     = {10.5281/zenodo.17615265},
  url     = {https://doi.org/10.5281/zenodo.17615265}
}

@article{xiaojuan2025-41139687,
  author  = {Xiaojuan, Li and Sonal, Singh and Andrea, DeVries and Gurwitz Jerry, H.},
  title   = {{Lecanemab Therapy Use Patterns for Alzheimer's Disease Among Early Initiators in a Large National Health Plan}},
  journal = {Journal of the American Geriatrics Society},
  year    = {2025},
  doi     = {10.1111/jgs.70010},
  pmid    = {41139687},
  url     = {https://doi.org/10.1111/jgs.70010}
}

@article{todkar2025-44a6f0db,
  author  = {Todkar, Rohit R. and Shirote, Pramodkumar J. and Mohite, Shrinivas Krishna},
  title   = {{In Silico Screening and DFT Analysis of Nelumbo nucifera Phytochemicals as Potential BACE-1 Inhibitors for Alzheimer’s disease}},
  journal = {Prospects in Pharmaceutical Sciences},
  year    = {2025},
  doi     = {10.56782/pps.379},
  url     = {https://doi.org/10.56782/pps.379}
}

@article{kang2025-41069006,
  author  = {Kang, Wenyan and Gao, Chao and Li, Xiaoyan and Wang, Xiaoxue and Zhong, Huizhu and Wei, Qiao and Tang, Yonghua and Huang, Peijian and others},
  title   = {{Safety and effectiveness of lecanemab in Chinese patients with early Alzheimer’s disease: Evidence from a multidimensional real-world study}},
  journal = {Chinese Medical Journal},
  year    = {2025},
  doi     = {10.1097/cm9.0000000000003888},
  pmid    = {41069006},
  url     = {https://doi.org/10.1097/cm9.0000000000003888}
}

@article{james2025-41061670,
  author  = {James, Rebecca E. and Bekier, Michael E. and Lee, P. and Schroeder, Frederick A. and Evans, Lauren Jayne and Wagner, Florence F. and Hickman, Dean and Richardson, Tom and others},
  title   = {{A next-generation HDAC6 inhibitor for amyotrophic lateral sclerosis and frontotemporal dementia}},
  journal = {Brain},
  year    = {2025},
  doi     = {10.1093/brain/awaf380},
  pmid    = {41061670},
  url     = {https://doi.org/10.1093/brain/awaf380}
}

@article{hansen2025-41052542,
  author  = {Hansen, Niels and Wiltfang, Jens},
  title   = {{Krankheitsmodifizierende Therapie mit Lecanemab bei früher Alzheimer-Demenz}},
  journal = {Fortschritte der Neurologie · Psychiatrie},
  year    = {2025},
  doi     = {10.1055/a-2681-4558},
  pmid    = {41052542},
  url     = {https://doi.org/10.1055/a-2681-4558}
}

@article{zoatier2025-41047159,
  author  = {Zoatier, Bayan and Yildiztekin, Gizem and Alagöz, Mehmet Abdullah and Hepokur, Ceylan and Dilek, Esra and Algül, Öztekin},
  title   = {{Benzoxazole Derivatives as Dual p38α Mitogen‐Activated Protein Kinase and Acetylcholinesterase Inhibitors: Design, Synthesis, and Evaluation for Alzheimer's Disease and Cancer Therapy}},
  journal = {ChemMedChem},
  year    = {2025},
  doi     = {10.1002/cmdc.202500669},
  pmid    = {41047159},
  url     = {https://doi.org/10.1002/cmdc.202500669}
}

@article{lee2025-01baa622,
  author  = {Lee, Wen-Teng},
  title   = {{GLP-1 Receptor Agonists Reduce Dementia and Alzheimer Disease Risk in Patients with Diabetes and Advanced CKD: Real-World Evidence from TriNetX}},
  journal = {Journal of the American Society of Nephrology},
  year    = {2025},
  doi     = {10.1681/asn.2025rdy8v05v},
  url     = {https://doi.org/10.1681/asn.2025rdy8v05v}
}

@article{abushakra2025-41015981,
  author  = {Abushakra, Susan R. and Power, Aidan and Watson, David and Porsteinsson, Anton P. and Sabbagh, Marwan and MacSweeney, Emer and Cohen, Sharon and Boada, Merçé and others},
  title   = {{Clinical Efficacy, Safety and Imaging Effects of Oral Valiltramiprosate in APOEε4/ε4 Homozygotes with Early Alzheimer’s Disease: Results of the Phase III, Randomized, Double-Blind, Placebo-Controlled, 78-Week APOLLOE4 Trial}},
  journal = {Drugs},
  year    = {2025},
  doi     = {10.1007/s40265-025-02250-5},
  pmid    = {41015981},
  url     = {https://doi.org/10.1007/s40265-025-02250-5}
}

@article{shami2026-40990233,
  author  = {Shami, R. and El Majzoub, R. and Ismail, A. and Kotaich, J. and Kassem, M. and Safadieh, G. and Fayyad-Kazan, M. and Chahine, B.},
  title   = {{Effects of triptolide herb on the progression of Alzheimer's disease preclinical models: a systematic review}},
  journal = {Neurodegenerative disease management},
  year    = {2026},
  doi     = {10.1080/17582024.2025.2562776},
  pmid    = {40990233},
  url     = {https://doi.org/10.1080/17582024.2025.2562776}
}

@article{pagan2025-40939527,
  author  = {Pagán, Fernando and Torres-Yaghi, Yasar A. and Hebron, Michaeline L. and Wilmarth, Barbara and Liu, Xiaoguang and Ahn, Jaeil and Moussa, Charbel},
  title   = {{Safety, tolerability and potential biomarkers of vodobatinib in patients with dementia with Lewy bodies}},
  journal = {Parkinsonism \& Related Disorders},
  year    = {2025},
  doi     = {10.1016/j.parkreldis.2025.108020},
  pmid    = {40939527},
  url     = {https://doi.org/10.1016/j.parkreldis.2025.108020}
}

@article{mamas2025-40980721,
  author  = {Mamas, Mamas A. and Bays, Harold Edward and Li, Runjia and Upadhyay, Navneet and Irani, Tanya and Şenyücel, Çağrı and Dunn, Julia P. and Liu‐Seifert, Hong},
  title   = {{Tirzepatide compared with semaglutide and 10-year cardiovascular disease risk reduction in obesity: post-hoc analysis of the SURMOUNT-5 trial}},
  journal = {European Heart Journal Open},
  year    = {2025},
  doi     = {10.1093/ehjopen/oeaf117},
  pmid    = {40980721},
  url     = {https://doi.org/10.1093/ehjopen/oeaf117}
}

@article{rubin2025-40844810,
  author  = {Rubin, Rita},
  title   = {{Treating Alzheimer Disease With Antiamyloid Therapies—The Real-World Experience Grows}},
  journal = {JAMA},
  year    = {2025},
  doi     = {10.1001/jama.2025.14180},
  pmid    = {40844810},
  url     = {https://doi.org/10.1001/jama.2025.14180}
}

@article{gibizov2025-51978b36,
  author  = {Gibizov, Yuriy A. and Вагапова, Л. Ш. and Aguzarova, Alina O. and Nazarova, Julia V. and Zotkina, Yana A. and Atamanyuk, Ekaterina A. and Rodikova, Mariia M. and Timergaleev, Rafael N. and others},
  title   = {{Physical Activity and the Myokine Irisin in Non-pharmacological Treatment of Alzheimer Disease}},
  journal = {Russian Journal of Physiotherapy Balneology and Rehabilitation},
  year    = {2025},
  doi     = {10.17816/rjpbr677844},
  url     = {https://doi.org/10.17816/rjpbr677844}
}

@article{allevi2025-40774851,
  author  = {Allevi, Dario and Luchicchi, Antonio and Orefice, Nicola Salvatore},
  title   = {{Nanocarrier-based drug delivery for mild cognitive impairment: Extracellular vesicles and carbon nanotubes as emerging therapeutic tools}},
  journal = {Biomedicine \& Pharmacotherapy},
  year    = {2025},
  doi     = {10.1016/j.biopha.2025.118381},
  pmid    = {40774851},
  url     = {https://doi.org/10.1016/j.biopha.2025.118381}
}

@article{koch2025-40809903,
  author  = {Koch, G. and Assogna, M. and Gadola, Y. and Alberici, A. and Di Lorenzo, F. and Bonnì, S. and Borghi, I. and Cerulli Irelli, E. and others},
  title   = {{Safety and efficacy of rotigotine in patients with frontotemporal dementia: a phase 2, double-blind, randomized, placebo-controlled, multicenter trial}},
  journal = {The Lancet regional health. Europe},
  year    = {2025},
  doi     = {10.1016/j.lanepe.2025.101409},
  pmid    = {40809903},
  url     = {https://doi.org/10.1016/j.lanepe.2025.101409}
}

@article{yu2025-40840993,
  author  = {Yu, Congcong and Yang, Huijie and Zhang, Bing and Chen, Shihua and Yang, Sijue and Li, Fangyi and Zhu, Wenhui and Zhai, Beibei and others},
  title   = {{Evaluating the effects of liraglutide, empagliflozin and linagliptin on mild cognitive impairment remission in patients with type 2 diabetes (LIGHT-MCI): study protocol for a multicentre, randomised controlled trial with an extension phase}},
  journal = {BMJ Open},
  year    = {2025},
  doi     = {10.1136/bmjopen-2024-095382},
  pmid    = {40840993},
  url     = {https://doi.org/10.1136/bmjopen-2024-095382}
}

@article{jacobson2025-40844772,
  author  = {Jacobson, M. and Molina-Henry, D. and Chang, T. Y. and Jimenez-Maggiora, G. A. and Pramanik, R. and Shah, S. B. and Aisen, P. S.},
  title   = {{Financial Incentives to Increase Diversity of Older Participants in a Memory Concerns Registry: A Randomized Clinical Trial}},
  journal = {JAMA health forum},
  year    = {2025},
  doi     = {10.1001/jamahealthforum.2025.2273},
  pmid    = {40844772},
  url     = {https://doi.org/10.1001/jamahealthforum.2025.2273}
}

@article{xia2025-40730714,
  author  = {Xia, X. and Aye, S. and Frisell, O. and Aho, E. and Handels, R. and Li, Y. and Wimo, A. and Winblad, B. and Eriksdotter, M. and Skillbäck, T. B. and Kern, S. and Zetterberg, H. and others},
  title   = {{The Cost-Effective Price of Lecanemab for Patients with Early Alzheimer's Disease in Sweden}},
  journal = {PharmacoEconomics},
  year    = {2025},
  doi     = {10.1007/s40273-025-01527-7},
  pmid    = {40730714},
  url     = {https://doi.org/10.1007/s40273-025-01527-7}
}

@article{yeon2025-40696527,
  author  = {Yeon, Jeon So and Sheng-Min, Wang and Woong, Roh Hyun and You, Kim Keun and Young, Chang Yoon and Eosu, Kim and Jae-Nam, Bae and Seung-Ho, Ryu},
  title   = {{Practical Guide of the Korean Association for Geriatric Psychiatry to Anti-Amyloid Monoclonal Antibody Therapy for Alzheimer's Disease: Focused on Lecanemab}},
  journal = {Journal of Korean medical science},
  year    = {2025},
  doi     = {10.3346/jkms.2025.40.e215},
  pmid    = {40696527},
  url     = {https://doi.org/10.3346/jkms.2025.40.e215}
}

@article{kehinde2025-40725274,
  author  = {Kehinde, S. A. and Lin, W. P. and Lay, B. B. and Phyo, K. Y. and San, M. M. and Pattanayaiying, R. and Chusri, S.},
  title   = {{Curcumin and Dementia: A Systematic Review of Its Effects on Oxidative Stress and Cognitive Outcomes in Animal Models}},
  journal = {International journal of molecular sciences},
  year    = {2025},
  doi     = {10.3390/ijms26147026},
  pmid    = {40725274},
  url     = {https://doi.org/10.3390/ijms26147026}
}

@article{forcano2025-40664536,
  author  = {Forcano, L. and Soldevila-Domenech, N. and Boronat, A. and Sánchez-Benavides, G. and Puig-Pijoan, A. and Lorenzo, T. and Aldea-Perona, A. and Suárez-Calvet, M. and others},
  title   = {{A multimodal lifestyle intervention complemented with epigallocatechin gallate to prevent cognitive decline in APOE- ɛ4 carriers with Subjective Cognitive Decline: a randomized, double-blinded clinical trial (PENSA study)}},
  journal = {The journal of prevention of Alzheimer's disease},
  year    = {2025},
  doi     = {10.1016/j.tjpad.2025.100271},
  pmid    = {40664536},
  url     = {https://doi.org/10.1016/j.tjpad.2025.100271}
}

@article{jessen2025-40640062,
  author  = {Jessen, Frank and Arbizu, Javier and Boada, Merçé and Balasa, Mircea and Bennys, Karim and Boban, Marina and Bürger, Katharina and Chincarini, A. and others},
  title   = {{Comment by European Alzheimer’s Disease Consortium (EADC) investigators on the negative recommendation of the CHMP on the marketing authorization of donanemab for early Alzheimer’ s disease}},
  journal = {The Journal of Prevention of Alzheimer s Disease},
  year    = {2025},
  doi     = {10.1016/j.tjpad.2025.100259},
  pmid    = {40640062},
  url     = {https://doi.org/10.1016/j.tjpad.2025.100259}
}

@article{sekikawa2025-40838083,
  author  = {Sekikawa, A. and Wharton, W. and Murray-Krezan, C. and Wu, M. and Chang, Y. and Snitz, B. E. and Coccari, M. and Yang, S. and others},
  title   = {{ACE trial design: Equol targeting estrogen receptor-β in vascular and cognitive aging}},
  journal = {Alzheimer's \& dementia (New York, N. Y.)},
  year    = {2025},
  doi     = {10.1002/trc2.70144},
  pmid    = {40838083},
  url     = {https://doi.org/10.1002/trc2.70144}
}

@article{huventgrelle2025-972a008a,
  author  = {Huvent‐Grelle, Dominique and HABIB, Nicolas and Puisieux, François L.},
  title   = {{Anti-amyloid immunotherapies for Alzheimer’s disease old people: eligibility and real life in a geriatric memory clinic in Lille (France)}},
  journal = {La Revue de gériatrie},
  year    = {2025},
  doi     = {10.62581/revgeri.21682},
  url     = {https://doi.org/10.62581/revgeri.21682}
}

@article{sun2025-40695613,
  author  = {Sun, Mingyang and Wang, Xiaoling and Lu, Zhongyuan and Yang, Yi and Lv, Shuang and Miao, Mengrong and Chen, Wanming and Wu, Szu‐Yuan and others},
  title   = {{Evaluating GLP-1 receptor agonists versus metformin as first-line therapy for reducing dementia risk in type 2 diabetes}},
  journal = {BMJ Open Diabetes Research \& Care},
  year    = {2025},
  doi     = {10.1136/bmjdrc-2025-004902},
  pmid    = {40695613},
  url     = {https://doi.org/10.1136/bmjdrc-2025-004902}
}

@article{nonino2025-40637522,
  author  = {Nonino, Francesco and Colosimo, Carlo and Massacesi, Luca},
  title   = {{Lecanemab e la malattia di Alzheimer-Perusini: tra speranze terapeutiche e sfide regolatorie}},
  journal = {Recenti Progressi in Medicina},
  year    = {2025},
  doi     = {10.1701/4530.45309},
  pmid    = {40637522},
  url     = {https://doi.org/10.1701/4530.45309}
}

@article{paczynski2025-40354064,
  author  = {Paczynski, M. and Hofmann, A. and Posey, Z. and Gregersen, M. and Rudman, M. and Ellington, D. and Aldinger, M. and Musiek, E. S. and Holtzman, D. M. and Bateman, R. J. and others},
  title   = {{Lecanemab Treatment in a Specialty Memory Clinic}},
  journal = {JAMA Neurology},
  year    = {2025},
  doi     = {10.1001/jamaneurol.2025.1232},
  pmid    = {40354064},
  url     = {https://doi.org/10.1001/jamaneurol.2025.1232}
}

@article{silveira2025-40587145,
  author  = {Silveira, C. R. A. and Coleman, K. K. L. and Borron, K. and Tirona, R. G. and Rupar, C. A. and Zou, G. and Hegele, R. A. and Wellington, C. and others},
  title   = {{Ambroxol as a Treatment for Parkinson Disease Dementia: A Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2025},
  doi     = {10.1001/jamaneurol.2025.1687},
  pmid    = {40587145},
  url     = {https://doi.org/10.1001/jamaneurol.2025.1687}
}

@article{akter2025-40649239,
  author  = {Akter, Sharmin and Tohge, Takayuki and Ananda, Sahithya Hulimane and Kuragano, Masahiro and Tokuraku, Kiyotaka and Uwai, Koji},
  title   = {{Anti-Amyloid Aggregation Effects of Gobaishi (Galla chinensis) and Its Active Constituents}},
  journal = {Molecules},
  year    = {2025},
  doi     = {10.3390/molecules30132720},
  pmid    = {40649239},
  url     = {https://doi.org/10.3390/molecules30132720}
}

@article{wang2025-40552638,
  author  = {Wang, William and Davis, Pamela B. and Qi, Xin and Gurney, Mark E. and Perry, George and Volkow, Nora D. and Kaelber, David C. and Xu, Rong},
  title   = {{Associations of semaglutide with Alzheimer's disease-related dementias in patients with type 2 diabetes: A real-world target trial emulation study}},
  journal = {Journal of Alzheimer s Disease},
  year    = {2025},
  doi     = {10.1177/13872877251351329},
  pmid    = {40552638},
  url     = {https://doi.org/10.1177/13872877251351329}
}

@article{schwartz2025-40584633,
  author  = {Schwartz, Nicholas U. and Dietz, Connor D. and Araújo, Igor Prufer and Villanueva-Meyer, Javier E. and Chiong, Winston and Lane‐Donovan, Courtney and VandeVrede, Lawren A. and Ljubenkov, Peter Alexander and others},
  title   = {{Changes of a Cerebral Cavernous Malformation Associated With Lecanemab Therapy in a Patient With Alzheimer Disease}},
  journal = {Neurology Clinical Practice},
  year    = {2025},
  doi     = {10.1212/cpj.0000000000200508},
  pmid    = {40584633},
  url     = {https://doi.org/10.1212/cpj.0000000000200508}
}

@article{knupflemacher2025-3c483de3,
  author  = {Knupflemacher, Daniel Sánchez and García, Xavier Antonio Sánchez and Salgado, Celina Nicole Angulo and Loyola, Paula Robert and Arce, Joel Santiago and Bautista, Ángel Gabriel Pérez},
  title   = {{Terapias emergentes para la enfermedad de Alzheimer: revisión sistemática de anticuerpos anti-amiloide y mecanismos alternativos}},
  journal = {Revista Científica de Salud y Desarrollo Humano},
  year    = {2025},
  doi     = {10.61368/r.s.d.h.v6i2.661},
  url     = {https://doi.org/10.61368/r.s.d.h.v6i2.661}
}

@article{xie2025-40709010,
  author  = {Xie, Qingping and Pak, Changsik John and Kwon, Jin Geun and Chao, Sung‐Chuan and Hong, Joon Pio},
  title   = {{Potential Role of Lymphovenous Bypass in Mitigating Alzheimer's Disease Dementia}},
  journal = {Archives of Plastic Surgery},
  year    = {2025},
  doi     = {10.1055/a-2627-9243},
  pmid    = {40709010},
  url     = {https://doi.org/10.1055/a-2627-9243}
}

@article{nordestgaard2025-40504878,
  author  = {Nordestgaard, Ask Tybjærg and Nordestgaard, Børge Grønne},
  title   = {{Remnant cholesterol lowering in cardiovascular disease risk reduction in statin, ezetimibe, and PCSK9 inhibitor trials: meta-regression analyses}},
  journal = {European Journal of Preventive Cardiology},
  year    = {2025},
  doi     = {10.1093/eurjpc/zwaf337},
  pmid    = {40504878},
  url     = {https://doi.org/10.1093/eurjpc/zwaf337}
}

@article{flicker2025-40511512,
  author  = {Flicker, L.},
  title   = {{Antiamyloid treatment for dementia: concerns outweigh hopes}},
  journal = {Current opinion in psychiatry},
  year    = {2025},
  doi     = {10.1097/yco.0000000000001021},
  pmid    = {40511512},
  url     = {https://doi.org/10.1097/yco.0000000000001021}
}

@article{bingke2025-40489822,
  author  = {Bingke, Xing and Jingran, Yang and Hui, Hua and Rong, Jiang},
  title   = {{Rapid health technology assessment of galantamine for the treatment of Alzheimer's disease: A review}},
  journal = {Medicine},
  year    = {2025},
  doi     = {10.1097/MD.0000000000042744},
  pmid    = {40489822},
  url     = {https://doi.org/10.1097/MD.0000000000042744}
}

@article{chen2025-40459787,
  author  = {Chen, Charles D. and Franklin, Erin E. and Li, Yan and Joseph‐Mathurin, Nelly and Burns, Aime and Hobbs, Diana A. and McCullough, Austin A. and Schultz, Stephanie A. and others},
  title   = {{Immunohistochemical evaluation of a trial of gantenerumab or solanezumab in dominantly inherited Alzheimer disease}},
  journal = {Acta Neuropathologica},
  year    = {2025},
  doi     = {10.1007/s00401-025-02890-7},
  pmid    = {40459787},
  url     = {https://doi.org/10.1007/s00401-025-02890-7}
}

@article{katsoulaki2025-40573227,
  author  = {Katsoulaki, Eleftheria-Emmanouela and Dimopoulos, Dimitrios and Hadjipavlou‐Litina, Dimitra},
  title   = {{Multitarget Compounds Designed for Alzheimer, Parkinson, and Huntington Neurodegeneration Diseases}},
  journal = {Pharmaceuticals},
  year    = {2025},
  doi     = {10.3390/ph18060831},
  pmid    = {40573227},
  url     = {https://doi.org/10.3390/ph18060831}
}

@article{albertyn2025-40479610,
  author  = {Albertyn, C. P. and Guu, T. W. and Chu, P. and Creese, B. and Young, A. and Velayudhan, L. and Bhattacharyya, S. and Jafari, H. and Kaur, S. and Kandangwa, P. and others},
  title   = {{Sativex (nabiximols) for the treatment of Agitation \& Aggression in Alzheimer's dementia in UK nursing homes: a randomised, double-blind, placebo-controlled feasibility trial}},
  journal = {Age and Ageing},
  year    = {2025},
  doi     = {10.1093/ageing/afaf149},
  pmid    = {40479610},
  url     = {https://doi.org/10.1093/ageing/afaf149}
}

@article{zhang2025-40521199,
  author  = {Zhang, Yueqi and Jiang, Lixian and Wu, Rongrong and Gao, Wei and Zhang, Xiaojie and Liu, Lan and Zhang, Yaxuan and others},
  title   = {{An AIM2 inflammasome biomimetic mineralization inhibitor for vascular dementia therapy}},
  journal = {Theranostics},
  year    = {2025},
  doi     = {10.7150/thno.110389},
  pmid    = {40521199},
  url     = {https://doi.org/10.7150/thno.110389}
}

@article{liu2025-40507855,
  author  = {Liu, X. and Baxley, S. and Hebron, M. and Turner, R. S. and Moussa, C.},
  title   = {{Resveratrol Attenuates CSF Markers of Neurodegeneration and Neuroinflammation in Individuals with Alzheimer's Disease}},
  journal = {International journal of molecular sciences},
  year    = {2025},
  doi     = {10.3390/ijms26115044},
  pmid    = {40507855},
  url     = {https://doi.org/10.3390/ijms26115044}
}

@article{lin2025-40405827,
  author  = {Lin, C. H. and Wang, S. H. and Lane, H. Y.},
  title   = {{Sodium benzoate, a D-amino acid oxidase inhibitor, improved short-term memory in patients with mild cognitive impairment in a randomized, double-blind, placebo-controlled clinical trial}},
  journal = {Psychiatry and clinical neurosciences},
  year    = {2025},
  doi     = {10.1111/pcn.13841},
  pmid    = {40405827},
  url     = {https://doi.org/10.1111/pcn.13841}
}

@article{bhogal2025-40404684,
  author  = {Bhogal, Inderjeet and Pankaj, Vaishali and Roy, Sudeep},
  title   = {{Identifying RAGE inhibitors as potential therapeutics for Alzheimer’s disease via integrated in-silico approaches}},
  journal = {Scientific Reports},
  year    = {2025},
  doi     = {10.1038/s41598-025-01271-0},
  pmid    = {40404684},
  url     = {https://doi.org/10.1038/s41598-025-01271-0}
}

@article{singhal2025-40359013,
  author  = {Singhal, Tarun and Cicero, Steven and Gale, Seth A. and Horan, Nicolas and Dubey, Shipra and Marshall, Gad A. and Weiner, Howard L.},
  title   = {{Dampening of Microglial Activation With Nasal Foralumab Administration in Moderate Alzheimer’s Disease Dementia}},
  journal = {Clinical Nuclear Medicine},
  year    = {2025},
  doi     = {10.1097/rlu.0000000000005955},
  pmid    = {40359013},
  url     = {https://doi.org/10.1097/rlu.0000000000005955}
}

@article{ameen2025-2abd646d,
  author  = {Ameen, Taha Basit and Ali, Umair and Salma, Omme and Samee, Muhammad Abdul and Abbas, Syed Muhammad Iraj and Kashif, Syeda Naveera and Arifi, Muhammad Arif and Ali, Mashooque and others},
  title   = {{Amyloid solutions: lecanemab, gantenerumab, and donanemab in the treatment of Alzheimer's disease}},
  journal = {The Egyptian Journal of Neurology Psychiatry and Neurosurgery},
  year    = {2025},
  doi     = {10.1186/s41983-025-00968-3},
  url     = {https://doi.org/10.1186/s41983-025-00968-3}
}

@article{zimmer2025-40063015,
  author  = {Zimmer, J. A. and Ardayfio, P. and Wang, H. and Khanna, R. and Evans, C. D. and Lu, M. and Sparks, J. and Andersen, S. and Lauzon, S. and Nery, E. S. M. and others},
  title   = {{Amyloid-Related Imaging Abnormalities With Donanemab in Early Symptomatic Alzheimer Disease: Secondary Analysis of the TRAILBLAZER-ALZ and ALZ 2 Randomized Clinical Trials}},
  journal = {JAMA Neurology},
  year    = {2025},
  doi     = {10.1001/jamaneurol.2025.0065},
  pmid    = {40063015},
  url     = {https://doi.org/10.1001/jamaneurol.2025.0065}
}

@article{salehiabargouei2025-40356047,
  author  = {Salehi‐Abargouei, Amin and Muka, Taulant and Collet, Tinh‐Hai and Kepp, Kasper P. and Chatelan, Angéline},
  title   = {{Comment on “Associations of semaglutide with first‐time diagnosis of Alzheimer's disease in patients with type 2 diabetes: Target trial emulation using nationwide real‐world data in the US”}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70035},
  pmid    = {40356047},
  url     = {https://doi.org/10.1002/alz.70035}
}

@article{qiu2025-40530730,
  author  = {Qiu, Yuyue and Shang, Li and Wang, Tianyi and Jiang, Yuhan and Bao, Jialu and Wang, Wenjun and Li, Bo and Huang, Yixuan and others},
  title   = {{Efficacy of Sodium Valproate in Behavioral and Psychological Symptoms of Dementia: A Retrospective Observational Study from PUMCH Dementia Cohort}},
  journal = {Current Alzheimer Research},
  year    = {2025},
  doi     = {10.2174/0115672050383192250610115920},
  pmid    = {40530730},
  url     = {https://doi.org/10.2174/0115672050383192250610115920}
}

@article{liu2025-41568736,
  author  = {Liu, Wenying and Li, Yan and Qin, Wei and Wang, Xuechu and Li, Wenwen and Li, Ying and {Alzheimer's Disease Neuroimaging Initiative} and Jia, Jianping},
  title   = {{The impact of cholinesterase inhibitors on cognitive trajectories in mild cognitive impairment patients based on amyloid beta status}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70193},
  pmid    = {41568736},
  url     = {https://doi.org/10.1002/alz.70193}
}

@article{temnik2025-40274975,
  author  = {Temnik, Max and Rudyk, Mariia P. and Балакин, А. А. and Gurin, Sergey and Dovbynchuk, Taisa and Byshovets, Roman and Dziubenko, Natalia and Tolstanova, Ganna M. and others},
  title   = {{Anti-inflammatory effects of 64Zn-aspartate is accompanied by cognitive improvements in rats with Aβ1-40-induced alzheimer disease}},
  journal = {Scientific Reports},
  year    = {2025},
  doi     = {10.1038/s41598-025-97830-6},
  pmid    = {40274975},
  url     = {https://doi.org/10.1038/s41598-025-97830-6}
}

@article{bu2025-40337511,
  author  = {Bu, Yifan and Li, Songzhe and Ye, Ting and Wang, Yuqing and Song, Mingrong and Chen, Jing},
  title   = {{Volatile oil of Acori tatarinowii rhizoma: potential candidate drugs for mitigating dementia}},
  journal = {Frontiers in Pharmacology},
  year    = {2025},
  doi     = {10.3389/fphar.2025.1552801},
  pmid    = {40337511},
  url     = {https://doi.org/10.3389/fphar.2025.1552801}
}

@article{bianchini2025-40231522,
  author  = {Bianchini, Matheus Chimelo and Franscescon, Francini and Soares, Adinei Abadio and Ansolin, Vinicius and Pretto, Kailane Paula and da Cunha, Marcelo Lemos Vieira and Silva, Débora Tavares de Resende e},
  title   = {{Potential Benefits of Quercetin through P2X7 Modulation against Neuroinflammation in Alzheimer's Disease}},
  journal = {Current Neuropharmacology},
  year    = {2025},
  doi     = {10.2174/011570159x355614250130100132},
  pmid    = {40231522},
  url     = {https://doi.org/10.2174/011570159x355614250130100132}
}

@article{felbecker2025-40222353,
  author  = {Felbecker, Ansgar and Rouaud, Olivier and Lathuilière, Aurélien and Allali, Gilles and Sollberger, Marc A. and Meyer-Heim, Tatjana and Monsch, Andreas Urs and Lövblad, Karl‐Olof and others},
  title   = {{Anti-Amyloid Monoclonal Antibodies for the Treatment of Alzheimer Disease: Intersocietal Recommendations for Their Appropriate Use in Switzerland}},
  journal = {Neurodegenerative Diseases},
  year    = {2025},
  doi     = {10.1159/000545799},
  pmid    = {40222353},
  url     = {https://doi.org/10.1159/000545799}
}

@article{donati2025-40217276,
  author  = {Donati, Monia and Boccia, Angelo Sabato and De Ponti, Fabrizio and Poluzzi, Elisabetta and Raschi, Emanuel},
  title   = {{Long-term surveillance of the anti-amyloid monoclonal antibody lecanemab: rights and duties of pharmacovigilance}},
  journal = {Alzheimer s Research \& Therapy},
  year    = {2025},
  doi     = {10.1186/s13195-025-01699-6},
  pmid    = {40217276},
  url     = {https://doi.org/10.1186/s13195-025-01699-6}
}

@article{bombonalban2025-ab04d0ab,
  author  = {Bombón-Albán, Paulina Elizabeth and Salazar, Johanna Vanessa Suárez and León, Lennyn Albán},
  title   = {{Lecanemab en la enfermedad de Alzheimer}},
  journal = {Acta neurológica colombiana},
  year    = {2025},
  doi     = {10.22379/anc.v41i2.1938},
  url     = {https://doi.org/10.22379/anc.v41i2.1938}
}

@article{jeremic2025-40194268,
  author  = {Jeremic, D. and Navarro-Lopez, J. D. and Jimenez-Diaz, L.},
  title   = {{Clinical Benefits and Risks of Antiamyloid Antibodies in Sporadic Alzheimer Disease: Systematic Review and Network Meta-Analysis With a Web Application}},
  journal = {Journal of medical Internet research},
  year    = {2025},
  doi     = {10.2196/68454},
  pmid    = {40194268},
  url     = {https://doi.org/10.2196/68454}
}

@article{tang2025-40193118,
  author  = {Tang, Huilin and Donahoo, William Troy and DeKosky, Steven T. and Lee, Yao An and Kotecha, Pareeta and Svensson, Mikael A. and Bian, Jiang and Guo, Jingchuan Serena},
  title   = {{GLP-1RA and SGLT2i Medications for Type 2 Diabetes and Alzheimer Disease and Related Dementias}},
  journal = {JAMA Neurology},
  year    = {2025},
  doi     = {10.1001/jamaneurol.2025.0353},
  pmid    = {40193118},
  url     = {https://doi.org/10.1001/jamaneurol.2025.0353}
}

@article{chen2025-40189473,
  author  = {Chen, Christopher and Katayama, Sadao and Lee, Jae Hong and Lee, Jun-Young and Nakagawa, Masaki and Torii, Kentaro and Ogawa, Tomoo and Dash, Amitabh and others},
  title   = {{Clarity AD: Asian regional analysis of a phase III trial of lecanemab in early Alzheimer's disease}},
  journal = {The Journal of Prevention of Alzheimer s Disease},
  year    = {2025},
  doi     = {10.1016/j.tjpad.2025.100160},
  pmid    = {40189473},
  url     = {https://doi.org/10.1016/j.tjpad.2025.100160}
}

@article{koch2025-40176122,
  author  = {Koch, Giacomo and Casula, Elias Paolo and Bonnı̀, Sonia and Borghi, Ilaria and Assogna, Martina and Di Lorenzo, Francesco and Esposito, Romina and Maiella, Michele and others},
  title   = {{Effects of 52 weeks of precuneus rTMS in Alzheimer’s disease patients: a randomized trial}},
  journal = {Alzheimer s Research \& Therapy},
  year    = {2025},
  doi     = {10.1186/s13195-025-01709-7},
  pmid    = {40176122},
  url     = {https://doi.org/10.1186/s13195-025-01709-7}
}

@article{wang2025-40172303,
  author  = {Wang, H. and Serap Monkul Nery, E. and Ardayfio, P. and Khanna, R. and Otero Svaldi, D. and Gueorguieva, I. and Shcherbinin, S. and Andersen, S. W. and Hauck, P. M. and Engle, S. E. and others},
  title   = {{Modified titration of donanemab reduces ARIA risk and maintains amyloid reduction}},
  journal = {Alzheimer's \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70062},
  pmid    = {40172303},
  url     = {https://doi.org/10.1002/alz.70062}
}

@article{richards2025-39909068,
  author  = {Richards, Kathy Culpepper and Fry, Liam and Lozano, Alicia J and Ji, Wenyan and Morrison, Janet and Britt, Katherine Carroll and Bliwise, Donald L. and Gooneratne, Nalaka Sudheera and others},
  title   = {{Treatment of Restless Legs Syndrome Improves Agitation and Sleep in Persons with Dementia: A Randomized Trial}},
  journal = {Journal of the American Medical Directors Association},
  year    = {2025},
  doi     = {10.1016/j.jamda.2025.105485},
  pmid    = {39909068},
  url     = {https://doi.org/10.1016/j.jamda.2025.105485}
}

@article{luchsinger2025-40434891,
  author  = {Luchsinger, J. A. and Devanand, D. and Goldberg, T. E. and Cammack, S. and Hernández-Santiago, G. and Oishi, K. and Jagust, W. and Baker, S. and others},
  title   = {{Protocol for a Randomized Phase II/III Double-Blind Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Extended-Release Metformin in Amnestic Mild Cognitive Impairment: Metformin in Alzheimer Dementia Prevention (MAP)}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2025},
  doi     = {10.1097/wad.0000000000000677},
  pmid    = {40434891},
  url     = {https://doi.org/10.1097/wad.0000000000000677}
}

@article{scheuermann2025-40306986,
  author  = {Scheuermann, Julia-Sophia and Scheerbaum, Petra and Liu, Yu and Ding, Yaping and Lu, Jianwen and Zhong, Ming and Su, Jian and Gefeller, Olaf and others},
  title   = {{SinoMAKS—protocol of a randomised controlled trial to evaluate the Chinese version of the non-pharmacological, multimodal MAKS intervention for people with mild to moderate dementia in Chinese nursing homes}},
  journal = {BMJ Open},
  year    = {2025},
  doi     = {10.1136/bmjopen-2024-093618},
  pmid    = {40306986},
  url     = {https://doi.org/10.1136/bmjopen-2024-093618}
}

@article{han2025-40159989,
  author  = {Han, X. and Gong, S. and Gong, J. and Wang, P. and Li, R. and Chen, R. and Xu, C. and Sun, W. and others},
  title   = {{Structural and metabolic topological alterations associated with butylphthalide treatment in mild cognitive impairment: Data from a randomized, double-blind, placebo-controlled trial}},
  journal = {Psychiatry and clinical neurosciences},
  year    = {2025},
  doi     = {10.1111/pcn.13812},
  pmid    = {40159989},
  url     = {https://doi.org/10.1111/pcn.13812}
}

@article{wright2025-40146982,
  author  = {Wright, K. D. and Richards Adams, I. K. and Helsabeck, N. P. and Rose, K. M. and Moss, K. O. and Nemati, D. and Palmer, N. and Kim, B. and others},
  title   = {{Stress and Hypertension Among African American Female Family Caregivers of Persons Living With Alzheimer Disease and Related Dementias: Protocol for a Pilot Internet-Based Randomized Controlled Trial}},
  journal = {JMIR research protocols},
  year    = {2025},
  doi     = {10.2196/66975},
  pmid    = {40146982},
  url     = {https://doi.org/10.2196/66975}
}

@article{rajji2025-40133524,
  author  = {Rajji, T. K. and Baksh, S. N. and Shade, D. M. and Ismail, Z. and Burhan, A. M. and Okhravi, H. R. and Padala, P. R. and Rosenberg, P. B. and Schneider, L. S. and Porsteinsson, A. P. and others},
  title   = {{Escitalopram for agitation in Alzheimer's dementia: a randomized controlled phase 3 trial}},
  journal = {Nature Medicine},
  year    = {2025},
  doi     = {10.1038/s41591-025-03569-y},
  pmid    = {40133524},
  url     = {https://doi.org/10.1038/s41591-025-03569-y}
}

@article{hunt2025-40126467,
  author  = {Hunt, Lauren J. and Gan, Siqi and Boscardin, W. John and Harrison, Krista Lyn and Growdon, Matthew E. and Muench, Ulrike and Gerlach, Lauren B. and Smith, Alexander Kingsbury and others},
  title   = {{Continued Use of Cholinesterase Inhibitors and Memantine in Hospice}},
  journal = {JAMA Internal Medicine},
  year    = {2025},
  doi     = {10.1001/jamainternmed.2024.8579},
  pmid    = {40126467},
  url     = {https://doi.org/10.1001/jamainternmed.2024.8579}
}

@article{rivasi2025-40067602,
  author  = {Rivasi, Giulia and Capacci, Marco and Del Re, Lorenzo Maria and Ambrosino, Ilaria and Ceolin, Ludovica and Liccardo, Alessandra and Bisignano, Maria Francesca and D’Ambrosio, Giuseppe and others},
  title   = {{Trazodone and Risk of Orthostatic Hypotension, Syncope and Falls in Geriatric Outpatients with Hypertension}},
  journal = {Drugs \& Aging},
  year    = {2025},
  doi     = {10.1007/s40266-025-01196-3},
  pmid    = {40067602},
  url     = {https://doi.org/10.1007/s40266-025-01196-3}
}

@article{sanz2025-d2104574,
  author  = {Sanz, Mercedes},
  title   = {{Lecanemab autorizado para tratamiento del Alzhéimer en pacientes que tienen una o ninguna copia de ApoE4: una reacción adversa grave limita su uso}},
  journal = {Panorama actual del medicamento},
  year    = {2025},
  doi     = {10.63105/pam8},
  url     = {https://doi.org/10.63105/pam8}
}

@article{tandoro2025-39939643,
  author  = {Tandoro, Yohanes and Chiu, Hui‐Fang and Tan, Chei-Ling and Hsieh, Ming‐Hong and Huang, Yi‐Wen and Yu, Jianhua and Wang, Li‐Shu and Chan, Chi‐Ho and others},
  title   = {{Black raspberry supplementation on overweight and Helicobacter pylori infected mild dementia patients a pilot study}},
  journal = {npj Science of Food},
  year    = {2025},
  doi     = {10.1038/s41538-024-00356-w},
  pmid    = {39939643},
  url     = {https://doi.org/10.1038/s41538-024-00356-w}
}

@article{khartabil2025-39998021,
  author  = {Khartabil, N. and Awaness, A.},
  title   = {{Targeting Amyloid Pathology in Early Alzheimer's: The Promise of Donanemab-Azbt}},
  journal = {Pharmacy (Basel, Switzerland)},
  year    = {2025},
  doi     = {10.3390/pharmacy13010023},
  pmid    = {39998021},
  url     = {https://doi.org/10.3390/pharmacy13010023}
}

@article{michaelian2025-39912236,
  author  = {Michaelian, Johannes C. and Rowe, Christopher C. and Kurrle, Susan E and Pond, Constance Dimity and Woodward, Michael and Naismith, Sharon Linda},
  title   = {{Is Australia ready for the rollout of amyloid‐targeting therapies for Alzheimer disease? Results from a national survey characterising current infrastructure capability, workforce and training needs of memory and cognition clinics}},
  journal = {Internal Medicine Journal},
  year    = {2025},
  doi     = {10.1111/imj.16637},
  pmid    = {39912236},
  url     = {https://doi.org/10.1111/imj.16637}
}

@article{matt2025-40009384,
  author  = {Matt, E. and Mitterwallner, M. and Radjenovic, S. and Grigoryeva, D. and Weber, A. and Stögmann, E. and Domitner, A. and Zettl, A. and others},
  title   = {{Ultrasound Neuromodulation With Transcranial Pulse Stimulation in Alzheimer Disease: A Randomized Clinical Trial}},
  journal = {JAMA network open},
  year    = {2025},
  doi     = {10.1001/jamanetworkopen.2024.59170},
  pmid    = {40009384},
  url     = {https://doi.org/10.1001/jamanetworkopen.2024.59170}
}

@article{dutta2025-39980415,
  author  = {Dutta, Sharmistha and Prabha, M. and Kiran, R.R. Siva and Ashoka, Hadagali},
  title   = {{Enhanced in silico QSAR-based screening of butyrylcholinesterase inhibitors using multi-feature selection and machine learning}},
  journal = {SAR and QSAR in environmental research},
  year    = {2025},
  doi     = {10.1080/1062936x.2025.2466020},
  pmid    = {39980415},
  url     = {https://doi.org/10.1080/1062936x.2025.2466020}
}

@article{liu2025-40137847,
  author  = {Liu, Haiyan and Zhou, J and Yang, W W},
  title   = {{Etomidate ameliorates Alzheimer-like neuropathology and cognitive impairment in APP/PS1 mice}},
  journal = {Journal of physiology and pharmacology : an official journal of the Polish Physiological Society},
  year    = {2025},
  doi     = {10.26402/jpp.2025.1.04},
  pmid    = {40137847},
  url     = {https://doi.org/10.26402/jpp.2025.1.04}
}

@article{titare2025-4e2f63cd,
  author  = {Titare, Vaishnavi Pravin and Salve, Mrs. Sneha K. and Kitukale, M. D.},
  title   = {{Novel Monoclonal Antibodies for the Treatment of Alzheimers Disease using KISUNLA Drug}},
  journal = {International Journal of Advanced Research in Science Communication and Technology},
  year    = {2025},
  doi     = {10.48175/ijarsct-23077},
  url     = {https://doi.org/10.48175/ijarsct-23077}
}

@article{ikemoto2025-e8a83631,
  author  = {Ikemoto, Keiko},
  title   = {{“D-Neuron Protection / Activation (DPA) Therapy”: New Strategy for Treatment of Neuropsychiatric Illnesses}},
  journal = {Advances in Bioengineering and Biomedical Science Research},
  year    = {2025},
  doi     = {10.33140/abbsr.08.01.01},
  url     = {https://doi.org/10.33140/abbsr.08.01.01}
}

@article{cummings2025-39780249,
  author  = {Cummings, J. L. and Atri, A. and Feldman, H. H. and Hansson, O. and Sano, M. and Knop, F. K. and Johannsen, P. and León, T. and others},
  title   = {{evoke and evoke+: design of two large-scale, double-blind, placebo-controlled, phase 3 studies evaluating efficacy, safety, and tolerability of semaglutide in early-stage symptomatic Alzheimer's disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2025},
  doi     = {10.1186/s13195-024-01666-7},
  pmid    = {39780249},
  url     = {https://doi.org/10.1186/s13195-024-01666-7}
}

@article{jeon2025-991821a1,
  author  = {Jeon, Heesu J. and Hinz, Lisa D.},
  title   = {{Enhancing Cognitive Functioning in Dementia Through Art Therapy: A Randomized Trial Based on the Expressive Therapies Continuum (ETC) Framework (Améliorer le fonctionnement cognitif chez les personnes atteintes de démence par l’art-thérapie : Un essai randomisé fondé sur le Continuum des thérapies expressives [CTE])}},
  journal = {Canadian Journal of Art Therapy},
  year    = {2025},
  doi     = {10.1080/26907240.2024.2446104},
  url     = {https://doi.org/10.1080/26907240.2024.2446104}
}

@article{crouzet2025-ff920d55,
  author  = {Crouzet, Christian and Liu, Jihua and Choi, Bernard and Cribbs, David H},
  title   = {{A Novel Mouse Model for Investigating ARIAs in Response to Anti-Abeta Immunotherapy}},
  journal = {Cerebral Circulation - Cognition and Behavior},
  year    = {2025},
  doi     = {10.1016/j.cccb.2025.100475},
  url     = {https://doi.org/10.1016/j.cccb.2025.100475}
}

@article{salloway2025-39556389,
  author  = {Salloway, S. and Wojtowicz, J. and Voyle, N. and Lane, C. A. and Klein, G. and Lyons, M. and Rossomanno, S. and Mazzo, F. and others},
  title   = {{Amyloid-Related Imaging Abnormalities (ARIA) in Clinical Trials of Gantenerumab in Early Alzheimer Disease}},
  journal = {JAMA neurology},
  year    = {2025},
  doi     = {10.1001/jamaneurol.2024.3937},
  pmid    = {39556389},
  url     = {https://doi.org/10.1001/jamaneurol.2024.3937}
}

@article{ayton2025-39495531,
  author  = {Ayton, S. and Barton, D. and Brew, B. and Brodtmann, A. and Clarnette, R. and Desmond, P. and Devos, D. and Ellis, K. A. and others},
  title   = {{Deferiprone in Alzheimer Disease: A Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2025},
  doi     = {10.1001/jamaneurol.2024.3733},
  pmid    = {39495531},
  url     = {https://doi.org/10.1001/jamaneurol.2024.3733}
}

@article{liu2025-40969222,
  author  = {Liu, Yumei and Zhu, Lin and Pei, Zian and Zhou, Zhifan and Su, Xiaolin and Ren, Huixia and Fan, Shuhan and Lan, Xiaoyong and others},
  title   = {{Integrating repetitive transcranial magnetic stimulation and Mediterranean diet for cognitive and anxiety improvement in early Alzheimer's disease: A case report and literature review}},
  journal = {Journal of Alzheimer s Disease Reports},
  year    = {2025},
  doi     = {10.1177/25424823251377988},
  pmid    = {40969222},
  url     = {https://doi.org/10.1177/25424823251377988}
}

@article{klein2025-b9ea469a,
  author  = {Klein, G. and Rabinovici, G. D. and Zetterberg, H. and others},
  title   = {{Interim biomarker results for trontinemab, a novel Brainshuttle antibody in development for the treatment of Alzheimer's disease}},
  journal = {Alzheimer's \& Dementia (AAIC 2025 conference abstract)},
  year    = {2025}
}

@article{duran2025-d42e1b7d,
  author  = {Durán, Stephanie Hernández and Ceja, Militza Jakeline Gómez},
  title   = {{Lecanemab como tratamiento en el deterioro cognitivo de pacientes con Alzheimer}},
  journal = {Acta Médica Grupo Ángeles},
  year    = {2025},
  doi     = {10.35366/119479},
  url     = {https://doi.org/10.35366/119479}
}

@article{cohen2025-acc6d80e,
  author  = {Cohen, S. and Ducharme, S. and Brosch, JR. and others},
  title   = {{Multiple-Dose Results from an Ongoing Phase 1 Study of Mivelsiran, an Investigational RNA Interference Therapeutic Targeting Amyloid-Beta Precursor Protein for Alzheimer's Disease}},
  journal = {Alzheimer's \& Dementia (AAIC 2025 conference abstract)},
  year    = {2025}
}

@article{ravi2025-40421258,
  author  = {Ravi, Renju and Das, Saibal and Hakami, Tahir M. and Prakash, Brahm and Pushparajan, Libby},
  title   = {{Pharmacotherapy for Poststroke Cognitive Impairment and Poststroke Cognitive Impairment With Dementia: A Review}},
  journal = {Stroke Research and Treatment},
  year    = {2025},
  doi     = {10.1155/srat/6893801},
  pmid    = {40421258},
  url     = {https://doi.org/10.1155/srat/6893801}
}

@article{study2025-1c190b50,
  title   = {{Therapierefraktärer Status epilepticus bei Therapie mit Anti-Amyloid-AK}},
  journal = {Neuroradiologie Scan},
  year    = {2025},
  doi     = {10.1055/a-2462-0741},
  url     = {https://doi.org/10.1055/a-2462-0741}
}

@article{grill2025-39671543,
  author  = {Grill, J. D. and Tam, S. and Thai, G. and Vides, B. and Pierce, A. L. and Green, K. and Gillen, D. L. and Teng, E. and others},
  title   = {{Phase 2A Proof-of-Concept Double-Blind, Randomized, Placebo-Controlled Trial of Nicotinamide in Early Alzheimer Disease}},
  journal = {Neurology},
  year    = {2025},
  doi     = {10.1212/wnl.0000000000210152},
  pmid    = {39671543},
  url     = {https://doi.org/10.1212/wnl.0000000000210152}
}

@article{abosharaf2024-39585487,
  author  = {Abosharaf, H. A. and Elsonbaty, Y. and Tousson, E. and Mohamed, T. M.},
  title   = {{Metformin effectively alleviates the symptoms of Alzheimer in rats by lowering amyloid β deposition and enhancing the insulin signal}},
  journal = {Metabolic brain disease},
  year    = {2024},
  doi     = {10.1007/s11011-024-01422-8},
  pmid    = {39585487},
  url     = {https://doi.org/10.1007/s11011-024-01422-8}
}

@article{linh2024-39548376,
  author  = {Linh, Duong Khanh and Heeyoon, Jung and Hyun-Kyoung, Lee and Jin, Moon Young and Ki, Lee Sang and Ram, Yang Bo and Hwi-Yeol, Yun and Jung-Woo, Chae},
  title   = {{Effect of choline alfoscerate in older adult patients with dementia: an observational study from the claims data of national health insurance}},
  journal = {BMC geriatrics},
  year    = {2024},
  doi     = {10.1186/s12877-024-05531-y},
  pmid    = {39548376},
  url     = {https://doi.org/10.1186/s12877-024-05531-y}
}

@article{study2024-6280b4fa,
  title   = {{Leqembi Recommended for Treatment of Early Alzheimer's Disease (CHMP re-examination, reversing July 2024 refusal)}},
  journal = {European Medicines Agency},
  year    = {2024}
}

@article{nakamura2024-39369280,
  author  = {Nakamura, Y. and Adachi, J. and Hirota, N. and Iba, K. and Shimizu, K. and Nakai, M. and Takahashi, K. and Mori, N.},
  title   = {{Brexpiprazole treatment for agitation in Alzheimer's dementia: A randomized study}},
  journal = {Alzheimer's \& Dementia},
  year    = {2024},
  doi     = {10.1002/alz.14282},
  pmid    = {39369280},
  url     = {https://doi.org/10.1002/alz.14282}
}

@article{wetmore2024-39748836,
  author  = {Wetmore, J. B. and Rodriguez, S. and Diaz Caro, D. and Cabán, M. and Uhlmann, W. and Goldman, J. and Leu, C. S. and Godinez, J. D. and others},
  title   = {{Designing and implementing the IDEAL Study: A randomized clinical trial of APOE genotype disclosure for late-onset Alzheimer's disease in an urban Latino population}},
  journal = {Alzheimer's \& dementia (New York, N. Y.)},
  year    = {2024},
  doi     = {10.1002/trc2.70016},
  pmid    = {39748836},
  url     = {https://doi.org/10.1002/trc2.70016}
}

@article{commission2024-91a12b9f,
  author  = {Commission, U.S. Securities and Exchange},
  title   = {{SEC Charges Cassava Sciences and Former Top Executives with Securities Fraud Related to Alzheimer's Drug Clinical Trial}},
  journal = {SEC Press Release / Administrative Order (Securities Act of 1933 Release No. 11311)},
  year    = {2024}
}

@article{oki2024-39229900,
  author  = {Oki, Y. and Osaki, T. and Kumagai, R. and Murata, S. and Encho, H. and Ono, R. and Yasuda, H. and Kowa, H.},
  title   = {{An 18-month multimodal intervention trial for preventing dementia: J-MINT PRIME Tamba}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2024},
  doi     = {10.1002/alz.14170},
  pmid    = {39229900},
  url     = {https://doi.org/10.1002/alz.14170}
}

@article{xu2024-39177108,
  author  = {Xu, H. and Habich, A. and Ferreira, D. and Elisabet, L. and Westman, E. and Eriksdotter, M.},
  title   = {{Long-term effects of cholinesterase inhibitors and memantine on cognitive decline, cardiovascular events, and mortality in dementia with Lewy bodies: An up to 10-year follow-up study}},
  journal = {Alzheimer's \& Dementia},
  year    = {2024},
  doi     = {10.1002/alz.14118},
  pmid    = {39177108},
  url     = {https://doi.org/10.1002/alz.14118}
}

@article{shinto2024-39088212,
  author  = {Shinto, L. H. and Murchison, C. F. and Silbert, L. C. and Dodge, H. H. and Lahna, D. and Rooney, W. and Kaye, J. and Quinn, J. F. and others},
  title   = {{ω-3 PUFA for Secondary Prevention of White Matter Lesions and Neuronal Integrity Breakdown in Older Adults: A Randomized Clinical Trial}},
  journal = {JAMA network open},
  year    = {2024},
  doi     = {10.1001/jamanetworkopen.2024.26872},
  pmid    = {39088212},
  url     = {https://doi.org/10.1001/jamanetworkopen.2024.26872}
}

@article{kaur2024-39136022,
  author  = {Kaur, S. and Sharma, K. and Sharma, A. and Sandha, K. K. and Ali, S. M. and Ahmed, R. and Ramajayan, P. and Singh, P. P. and others},
  title   = {{Fluvoxamine maleate alleviates amyloid-beta load and neuroinflammation in 5XFAD mice to ameliorate Alzheimer disease pathology}},
  journal = {Frontiers in immunology},
  year    = {2024},
  doi     = {10.3389/fimmu.2024.1418422},
  pmid    = {39136022},
  url     = {https://doi.org/10.3389/fimmu.2024.1418422}
}

@article{study2024-7f8e71c0,
  title   = {{FDA Approves Treatment for Adults with Alzheimer's Disease (Kisunla / donanemab-azbt)}},
  journal = {U.S. Food and Drug Administration},
  year    = {2024}
}

@article{haroon2024-39058809,
  author  = {Haroon, J. and Jordan, K. and Mahdavi, K. and Rindner, E. and Becerra, S. and Surya, JR. and Zielinski, M. and Venkatraman, V. and others},
  title   = {{A phase 2, open-label study of anti-inflammatory NE3107 in patients with dementias}},
  journal = {Medicine},
  year    = {2024},
  doi     = {10.1097/md.0000000000039027},
  pmid    = {39058809},
  url     = {https://doi.org/10.1097/md.0000000000039027}
}

@article{lee2024-38875437,
  author  = {Lee, W. and Kim, M.},
  title   = {{Comparative study of choline alfoscerate as a combination therapy with donepezil: A mixed double-blind randomized controlled and open-label observation trial}},
  journal = {Medicine},
  year    = {2024},
  doi     = {10.1097/md.0000000000038067},
  pmid    = {38875437},
  url     = {https://doi.org/10.1097/md.0000000000038067}
}

@article{wagemann2024-38683602,
  author  = {Wagemann, O. and Liu, H. and Wang, G. and Shi, X. and Bittner, T. and Scelsi, M. A. and Farlow, M. R. and Clifford, D. B. and others},
  title   = {{Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease: The DIAN-TU-001 Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2024},
  doi     = {10.1001/jamaneurol.2024.0991},
  pmid    = {38683602},
  url     = {https://doi.org/10.1001/jamaneurol.2024.0991}
}

@article{yuan2024-38824515,
  author  = {Yuan, Y. and Yang, Y. and Hu, X. and Zhang, L. and Xiong, Z. and Bai, Y. and others},
  title   = {{Effective dosage and mode of exercise for enhancing cognitive function in Alzheimer's disease and dementia: a systematic review and Bayesian Model-Based Network Meta-analysis of RCTs}},
  journal = {BMC Geriatrics},
  year    = {2024},
  doi     = {10.1186/s12877-024-05060-8},
  pmid    = {38824515},
  url     = {https://doi.org/10.1186/s12877-024-05060-8}
}

@article{thunborg2024-38812047,
  author  = {Thunborg, C. and Wang, R. and Rosenberg, A. and Sindi, S. and Andersen, P. and Andrieu, S. and Broersen, L. M. and Coley, N. and others},
  title   = {{Integrating a multimodal lifestyle intervention with medical food in prodromal Alzheimer's disease: the MIND-ADmini randomized controlled trial}},
  journal = {Alzheimer's research \& therapy},
  year    = {2024},
  doi     = {10.1186/s13195-024-01468-x},
  pmid    = {38812047},
  url     = {https://doi.org/10.1186/s13195-024-01468-x}
}

@article{havrengthery2024-38812028,
  author  = {Havreng-Théry, C. and Oquendo, B. and Zolnowski-Kolp, V. and Krolak-Salmon, P. and Bertin-Hugault, F. and Lafuente-Lafuente, C. and Belmin, J.},
  title   = {{Cholinesterase inhibitors and memantine are associated with a reduced mortality in nursing home residents with dementia: a longitudinal observational study}},
  journal = {Alzheimer's Research \& Therapy},
  year    = {2024},
  doi     = {10.1186/s13195-024-01481-0},
  pmid    = {38812028},
  url     = {https://doi.org/10.1186/s13195-024-01481-0}
}

@article{shanks2024-38760589,
  author  = {Shanks, H. R. C. and Chen, K. and Reiman, E. M. and Blennow, K. and Cummings, J. L. and Massa, S. M. and Longo, F. M. and Börjesson-Hanson, A. and others},
  title   = {{p75 neurotrophin receptor modulation in mild to moderate Alzheimer disease: a randomized, placebo-controlled phase 2a trial}},
  journal = {Nature medicine},
  year    = {2024},
  doi     = {10.1038/s41591-024-02977-w},
  pmid    = {38760589},
  url     = {https://doi.org/10.1038/s41591-024-02977-w}
}

@article{sevigny2024-38745011,
  author  = {Sevigny, J. and Uspenskaya, O. and Heckman, L. D. and Wong, L. C. and Hatch, D. A. and Tewari, A. and Vandenberghe, R. and Irwin, D. J. and others},
  title   = {{Progranulin AAV gene therapy for frontotemporal dementia: translational studies and phase 1/2 trial interim results}},
  journal = {Nature medicine},
  year    = {2024},
  doi     = {10.1038/s41591-024-02973-0},
  pmid    = {38745011},
  url     = {https://doi.org/10.1038/s41591-024-02973-0}
}

@article{honig2024-38730496,
  author  = {Honig, L. S. and Sabbagh, M. N. and van Dyck, C. H. and Sperling, R. A. and Hersch, S. and Matta, A. and Giorgi, L. and Gee, M. and others},
  title   = {{Updated safety results from phase 3 lecanemab study in early Alzheimer's disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2024},
  doi     = {10.1186/s13195-024-01441-8},
  pmid    = {38730496},
  url     = {https://doi.org/10.1186/s13195-024-01441-8}
}

@article{jung2024-38709534,
  author  = {Jung, Y. H. and Jang, H. and Park, S. and Kim, H. J. and Seo, S. W. and Kim, G. B. and Shon, Y. M. and Kim, S. and others},
  title   = {{Effectiveness of Personalized Hippocampal Network-Targeted Stimulation in Alzheimer Disease: A Randomized Clinical Trial}},
  journal = {JAMA network open},
  year    = {2024},
  doi     = {10.1001/jamanetworkopen.2024.9220},
  pmid    = {38709534},
  url     = {https://doi.org/10.1001/jamanetworkopen.2024.9220}
}

@article{holscher2024-38677445,
  author  = {Hölscher, C.},
  title   = {{Glucagon-like peptide-1 class drugs show clear protective effects in Parkinson's and Alzheimer's disease clinical trials: A revolution in the making?}},
  journal = {Neuropharmacology},
  year    = {2024},
  doi     = {10.1016/j.neuropharm.2024.109952},
  pmid    = {38677445},
  url     = {https://doi.org/10.1016/j.neuropharm.2024.109952}
}

@article{nguyen2024-38484190,
  author  = {Nguyen, H. V. and Mital, S. and Knopman, D. S. and Alexander, G. C.},
  title   = {{Cost-Effectiveness of Lecanemab for Individuals With Early-Stage Alzheimer Disease}},
  journal = {Neurology},
  year    = {2024},
  doi     = {10.1212/WNL.0000000000209218},
  pmid    = {38484190},
  url     = {https://doi.org/10.1212/WNL.0000000000209218}
}

@article{fleisher2024-38386949,
  author  = {Fleisher, A. S. and Munsie, L. M. and Perahia, D. G. S. and Andersen, S. W. and Higgins, I. A. and Hauck, P. M. and Lo, A. C. and Sims, JR. and others},
  title   = {{Assessment of Efficacy and Safety of Zagotenemab: Results From PERISCOPE-ALZ, a Phase 2 Study in Early Symptomatic Alzheimer Disease}},
  journal = {Neurology},
  year    = {2024},
  doi     = {10.1212/wnl.0000000000208061},
  pmid    = {38386949},
  url     = {https://doi.org/10.1212/wnl.0000000000208061}
}

@article{adesuyan2024-38324745,
  author  = {Adesuyan, M. and Jani, Y. H. and Alsugeir, D. and Howard, R. and Ju, C. and Wei, L. and Brauer, R.},
  title   = {{Phosphodiesterase Type 5 Inhibitors in Men With Erectile Dysfunction and the Risk of Alzheimer Disease: A Cohort Study}},
  journal = {Neurology},
  year    = {2024},
  doi     = {10.1212/wnl.0000000000209131},
  pmid    = {38324745},
  url     = {https://doi.org/10.1212/wnl.0000000000209131}
}

@article{luo2024-38510996,
  author  = {Luo, Xuemei and de Chaves, Jakson Roberto Gaeski and Dhamane, Amol D. and Dai, Feng and Latrémouille-Viau, Dominick and Wang, Aolin},
  title   = {{Delayed treatment initiation of oral anticoagulants among Medicare patients with atrial fibrillation}},
  journal = {American Heart Journal Plus Cardiology Research and Practice},
  year    = {2024},
  doi     = {10.1016/j.ahjo.2024.100369},
  pmid    = {38510996},
  url     = {https://doi.org/10.1016/j.ahjo.2024.100369}
}

@article{savall2024-38391705,
  author  = {Savall, A. S. P. and de Mello, J. D. and Fidelis, E. M. and Comis-Neto, A. A. and Nepomuceno, M. R. and Pacheco, C. O. and Haas, S. E. and Pinton, S.},
  title   = {{Nanoencapsulated Curcumin: Enhanced Efficacy in Reversing Memory Loss in An Alzheimer Disease Model}},
  journal = {Brain sciences},
  year    = {2024},
  doi     = {10.3390/brainsci14020130},
  pmid    = {38391705},
  url     = {https://doi.org/10.3390/brainsci14020130}
}

@article{wang2024-228e687c,
  author  = {Wang, W. and Wang, Q. Q. and Qi, X. and Gurney, M. and Perry, G. and Volkow, N. D. and Davis, P. B. and Kaelber, D. C. and Xu, R.},
  title   = {{Associations of semaglutide with first-time diagnosis of Alzheimer's disease in patients with type 2 diabetes: Target trial emulation using nationwide real-world data in the US}},
  journal = {Alzheimer's \& Dementia},
  year    = {2024}
}

@article{ebell2024-38253509,
  author  = {Ebell, M. H. and Barry, H. C. and Baduni, K. and Grasso, G.},
  title   = {{Clinically Important Benefits and Harms of Monoclonal Antibodies Targeting Amyloid for the Treatment of Alzheimer Disease: A Systematic Review and Meta-Analysis}},
  journal = {Annals of Family Medicine},
  year    = {2024},
  doi     = {10.1370/afm.3050},
  pmid    = {38253509},
  url     = {https://doi.org/10.1370/afm.3050}
}

@article{loomis2024-38165296,
  author  = {Loomis, S. J. and Miller, R. and Castrillo-Viguera, C. and Umans, K. and Cheng, W. and O'Gorman, J. and Hughes, R. and Budd Haeberlein, S. and others},
  title   = {{Genome-Wide Association Studies of ARIA From the Aducanumab Phase 3 ENGAGE and EMERGE Studies}},
  journal = {Neurology},
  year    = {2024},
  doi     = {10.1212/wnl.0000000000207919},
  pmid    = {38165296},
  url     = {https://doi.org/10.1212/wnl.0000000000207919}
}

@article{park2024-38095619,
  author  = {Park, J. and Simpson, C. and Patel, K.},
  title   = {{Lecanemab: A Humanized Monoclonal Antibody for the Treatment of Early Alzheimer Disease}},
  journal = {The Annals of pharmacotherapy},
  year    = {2024},
  doi     = {10.1177/10600280231218253},
  pmid    = {38095619},
  url     = {https://doi.org/10.1177/10600280231218253}
}

@article{ghorat2024-38069542,
  author  = {Ghorat, F. and Sepidarkish, M. and Saadattalab, F. and Rezghi, M. and Shahrestani, S. and Gholamalizadeh, M. and Doaei, S.},
  title   = {{The clinical efficacy of Olibanum gum chewing in patients with Mild-to-Moderate Alzheimer disease: A randomized Parallel-Design controlled trial}},
  journal = {Neuropsychopharmacology reports},
  year    = {2024},
  doi     = {10.1002/npr2.12398},
  pmid    = {38069542},
  url     = {https://doi.org/10.1002/npr2.12398}
}

@article{lee2023-37930669,
  author  = {Lee, D. and Slomkowski, M. and Hefting, N. and Chen, D. and Larsen, K. G. and Kohegyi, E. and Hobart, M. and Cummings, J. L. and others},
  title   = {{Brexpiprazole for the Treatment of Agitation in Alzheimer Dementia: A Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2023},
  doi     = {10.1001/jamaneurol.2023.3810},
  pmid    = {37930669},
  url     = {https://doi.org/10.1001/jamaneurol.2023.3810}
}

@article{saito2023-38048134,
  author  = {Saito, S. and Suzuki, K. and Ohtani, R. and Maki, T. and Kowa, H. and Tachibana, H. and Washida, K. and Kawabata, N. and others},
  title   = {{Efficacy and Safety of Cilostazol in Mild Cognitive Impairment: A Randomized Clinical Trial}},
  journal = {JAMA network open},
  year    = {2023},
  doi     = {10.1001/jamanetworkopen.2023.44938},
  pmid    = {38048134},
  url     = {https://doi.org/10.1001/jamanetworkopen.2023.44938}
}

@article{rustamzadeh2023-38318412,
  author  = {Rustamzadeh, A. and Sadigh, N. and Shabani, R. and Ahadi, R. and Vahabi, Z. and Shabani, A. and Mohebi, N. and Khamseh, F. and others},
  title   = {{Neurochemical Ameliorating of the Hippocampus in Dyslipidemic Alzheimer Patients Following Silymarin; a Double-Blind Placebo-Controlled Randomized Clinical Trial}},
  journal = {Medical journal of the Islamic Republic of Iran},
  year    = {2023},
  doi     = {10.47176/mjiri.37.123},
  pmid    = {38318412},
  url     = {https://doi.org/10.47176/mjiri.37.123}
}

@article{luo2023-9f1100a2,
  author  = {Luo, Xiaochan and de Chaves, Jakson Roberto Gaeski and Wang, Andrew and Steffen, David R. and Dhamane, A D and Dai, Feng},
  title   = {{Factors associated with delayed treatment initiation of oral anticoagulants among Medicare patients with atrial fibrillation}},
  journal = {European Heart Journal},
  year    = {2023},
  doi     = {10.1093/eurheartj/ehad655.535},
  url     = {https://doi.org/10.1093/eurheartj/ehad655.535}
}

@article{bateman2023-37966285,
  author  = {Bateman, R. J. and Smith, J. and Donohue, M. C. and Delmar, P. and Abbas, R. and Salloway, S. and Wojtowicz, J. and Blennow, K. and others},
  title   = {{Two Phase 3 Trials of Gantenerumab in Early Alzheimer's Disease}},
  journal = {The New England journal of medicine},
  year    = {2023},
  doi     = {10.1056/nejmoa2304430},
  pmid    = {37966285},
  url     = {https://doi.org/10.1056/nejmoa2304430}
}

@article{grill2024-37830926,
  author  = {Grill, J. D. and Flournoy, C. and Dhadda, S. and Ernstrom, K. and Sperling, R. and Molina-Henry, D. and Tranotti, K. and Harris, R. and others},
  title   = {{Eligibility Rates among Racially and Ethnically Diverse US Participants in Phase 2 and Phase 3 Placebo-Controlled, Double-Blind, Randomized Trials of Lecanemab and Elenbecestat in Early Alzheimer Disease}},
  journal = {Annals of neurology},
  year    = {2024},
  doi     = {10.1002/ana.26819},
  pmid    = {37830926},
  url     = {https://doi.org/10.1002/ana.26819}
}

@article{bracco2023-37875856,
  author  = {Bracco, L. and Pinto-Carral, A. and Hillaert, L. and Mourey, F.},
  title   = {{Tango-therapy vs physical exercise in older people with dementia; a randomized controlled trial}},
  journal = {BMC geriatrics},
  year    = {2023},
  doi     = {10.1186/s12877-023-04342-x},
  pmid    = {37875856},
  url     = {https://doi.org/10.1186/s12877-023-04342-x}
}

@article{delrieu2023-37872582,
  author  = {Delrieu, J. and Vellas, B. and Guyonnet, S. and Cantet, C. and Ovod, V. and Li, Y. and Bollinger, J. and Bateman, R. and others},
  title   = {{Cognitive impact of multidomain intervention and omega 3 according to blood Aβ42/40 ratio: a subgroup analysis from the randomized MAPT trial}},
  journal = {Alzheimer's research \& therapy},
  year    = {2023},
  doi     = {10.1186/s13195-023-01325-3},
  pmid    = {37872582},
  url     = {https://doi.org/10.1186/s13195-023-01325-3}
}

@article{woodworth2023-37831492,
  author  = {Woodworth, E. C. and Briskin, E. A. and Plys, E. and Macklin, E. and Tatar, R. G. and Huberty, J. and Vranceanu, A. M.},
  title   = {{Mindfulness-Based App to Reduce Stress in Caregivers of Persons With Alzheimer Disease and Related Dementias: Protocol for a Single-Blind Feasibility Proof-of-Concept Randomized Controlled Trial}},
  journal = {JMIR research protocols},
  year    = {2023},
  doi     = {10.2196/50108},
  pmid    = {37831492},
  url     = {https://doi.org/10.2196/50108}
}

@article{monteiro2023-1c8f9366,
  author  = {Monteiro, C. and Toth, B. and Brunstein, F. and Bobbala, A. and Datta, S. and Ceniceros, R. and Sanabria Bohorquez, S. M. and Anania, V. G. and Wildsmith, K. R. and Schauer, S. P. and Lee, J. and Dolton, M. J. and Ramakrishnan, V. and Abramzon, D. and Teng, E. and {the Lauriet investigators}},
  title   = {{Randomized Phase II Study of the Safety and Efficacy of Semorinemab in Participants With Mild-to-Moderate Alzheimer Disease: Lauriet}},
  journal = {Neurology},
  year    = {2023},
  doi     = {10.1212/wnl.0000000000207663},
  pmid    = {37643887},
  url     = {https://doi.org/10.1212/wnl.0000000000207663}
}

@article{monteiro2023-37643887,
  author  = {Monteiro, C. and Toth, B. and Brunstein, F. and Bobbala, A. and Datta, S. and Ceniceros, R. and Sanabria Bohorquez, S. M. and Anania, V. G. and others},
  title   = {{Randomized Phase II Study of the Safety and Efficacy of Semorinemab in Participants With Mild-to-Moderate Alzheimer Disease: Lauriet}},
  journal = {Neurology},
  year    = {2023},
  doi     = {10.1212/wnl.0000000000207663},
  pmid    = {37643887},
  url     = {https://doi.org/10.1212/wnl.0000000000207663}
}

@article{sims2023-37459141,
  author  = {Sims, JR. and Zimmer, J. A. and Evans, C. D. and Lu, M. and Ardayfio, P. and Sparks, J. and Wessels, A. M. and Shcherbinin, S. and others},
  title   = {{Donanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial}},
  journal = {JAMA},
  year    = {2023},
  doi     = {10.1001/jama.2023.13239},
  pmid    = {37459141},
  url     = {https://doi.org/10.1001/jama.2023.13239}
}

@article{papatsimpas2023-37509042,
  author  = {Papatsimpas, V. and Vrouva, S. and Papathanasiou, G. and Papadopoulou, M. and Bouzineki, C. and Kanellopoulou, S. and Moutafi, D. and Bakalidou, D.},
  title   = {{Does Therapeutic Exercise Support Improvement in Cognitive Function and Instrumental Activities of Daily Living in Patients with Mild Alzheimer's Disease? A Randomized Controlled Trial}},
  journal = {Brain sciences},
  year    = {2023},
  doi     = {10.3390/brainsci13071112},
  pmid    = {37509042},
  url     = {https://doi.org/10.3390/brainsci13071112}
}

@article{sims2023-9857475c,
  author  = {Sims, JR. and Zimmer, J. A. and Evans, C. D. and Lu, M. and Ardayfio, P. and Sparks, J. and Wessels, A. M. and Shcherbinin, S. and Wang, H. and Monkul Nery, E. S. and Collins, E. C. and Solomon, P. and Salloway, S. and Apostolova, L. G. and Hansson, O. and Ritchie, C. and Brooks, D. A. and Mintun, M. and Skovronsky, D. M. and {TRAILBLAZER-ALZ 2 Investigators}},
  title   = {{Donanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial}},
  journal = {JAMA},
  year    = {2023},
  pmid    = {37459141}
}

@article{kim2023-37403351,
  author  = {Kim, A. and Lee, J. and Moon, H. and Kim, C. and Yoo, M. Y. and Park, W. Y. and Kim, W. D. and Seo, Y. S.},
  title   = {{The effects of low-dose radiation therapy in patients with mild-to-moderate Alzheimer's dementia: an interim analysis of a pilot study}},
  journal = {Radiation oncology journal},
  year    = {2023},
  doi     = {10.3857/roj.2023.00052},
  pmid    = {37403351},
  url     = {https://doi.org/10.3857/roj.2023.00052}
}

@article{alidoust2023-37311523,
  author  = {Alidoust, L. and Akhoondian, M. and Atefi, A. H. and Keivanlou, M. H. and Hedayati Ch, M. and Jafari, A.},
  title   = {{Stem cell-conditioned medium is a promising treatment for Alzheimer's disease}},
  journal = {Behavioural brain research},
  year    = {2023},
  doi     = {10.1016/j.bbr.2023.114543},
  pmid    = {37311523},
  url     = {https://doi.org/10.1016/j.bbr.2023.114543}
}

@article{voigt2023-37277877,
  author  = {Voigt, S. and Koemans, E. A. and Rasing, I. and van Etten, E. S. and Terwindt, G. M. and Baas, F. and Kaushik, K. and van Es, A. C. G. M. and others},
  title   = {{Minocycline for sporadic and hereditary cerebral amyloid angiopathy (BATMAN): study protocol for a placebo-controlled randomized double-blind trial}},
  journal = {Trials},
  year    = {2023},
  doi     = {10.1186/s13063-023-07371-4},
  pmid    = {37277877},
  url     = {https://doi.org/10.1186/s13063-023-07371-4}
}

@article{florian2023-36730056,
  author  = {Florian, H. and Wang, D. and Arnold, S. E. and Boada, M. and Guo, Q. and Jin, Z. and Zheng, H. and Fisseha, N. and others},
  title   = {{Tilavonemab in early Alzheimer's disease: results from a phase 2, randomized, double-blind study}},
  journal = {Brain : a journal of neurology},
  year    = {2023},
  doi     = {10.1093/brain/awad024},
  pmid    = {36730056},
  url     = {https://doi.org/10.1093/brain/awad024}
}

@article{study2023-40d8b15f,
  title   = {{Lecanemab for Alzheimer's Disease: Effectiveness and Value — Final Evidence Report}},
  journal = {ICER (independent health technology assessment report)},
  year    = {2023}
}

@article{berry2023-37040116,
  author  = {Berry, D. A. and Dhadda, S. and Kanekiyo, M. and Li, D. and Swanson, C. J. and Irizarry, M. and Kramer, L. D. and Berry, S. M.},
  title   = {{Lecanemab for Patients With Early Alzheimer Disease: Bayesian Analysis of a Phase 2b Dose-Finding Randomized Clinical Trial}},
  journal = {JAMA network open},
  year    = {2023},
  doi     = {10.1001/jamanetworkopen.2023.7230},
  pmid    = {37040116},
  url     = {https://doi.org/10.1001/jamanetworkopen.2023.7230}
}

@article{study2023-955fa2a8,
  title   = {{Interim Phase 1 multiple ascending dose results for remternetug (LY3372993) in Alzheimer's disease}},
  journal = {Presented at AD/PD 2023 Conference (Gothenburg, Sweden); covered by ALZFORUM and NeurologyLive},
  year    = {2023}
}

@article{rogers2023-36935024,
  author  = {Rogers, C. L. and Lageman, S. K. and Fontanesi, J. and Wilson, G. D. and Boling, P. A. and Bansal, S. and Karis, J. P. and Sabbagh, M. and others},
  title   = {{Low-Dose Whole Brain Radiation Therapy for Alzheimer's Dementia: Results From a Pilot Trial in Humans}},
  journal = {International journal of radiation oncology, biology, physics},
  year    = {2023},
  doi     = {10.1016/j.ijrobp.2023.03.044},
  pmid    = {36935024},
  url     = {https://doi.org/10.1016/j.ijrobp.2023.03.044}
}

@article{agarwal2023-36889921,
  author  = {Agarwal, P. and Leurgans, S. E. and Agrawal, S. and Aggarwal, N. T. and Cherian, L. J. and James, B. D. and Dhana, K. and others},
  title   = {{Association of Mediterranean-DASH Intervention for Neurodegenerative Delay and Mediterranean Diets With Alzheimer Disease Pathology}},
  journal = {Neurology},
  year    = {2023},
  doi     = {10.1212/wnl.0000000000207176},
  pmid    = {36889921},
  url     = {https://doi.org/10.1212/wnl.0000000000207176}
}

@article{knopman2023-36948153,
  author  = {Knopman, D. S.},
  title   = {{Lecanemab reduces brain amyloid-β and delays cognitive worsening}},
  journal = {Cell reports. Medicine},
  year    = {2023},
  doi     = {10.1016/j.xcrm.2023.100982},
  pmid    = {36948153},
  url     = {https://doi.org/10.1016/j.xcrm.2023.100982}
}

@article{vitek2023-36749830,
  author  = {Vitek, G. E. and Decourt, B. and Sabbagh, M. N.},
  title   = {{Lecanemab (BAN2401): an anti-beta-amyloid monoclonal antibody for the treatment of Alzheimer disease}},
  journal = {Expert opinion on investigational drugs},
  year    = {2023},
  doi     = {10.1080/13543784.2023.2178414},
  pmid    = {36749830},
  url     = {https://doi.org/10.1080/13543784.2023.2178414}
}

@article{dubois2023-36849969,
  author  = {Dubois, B. and López-Arrieta, J. and Lipschitz, S. and Doskas, T. and Spiru, L. and Moroz, S. and Venger, O. and Vermersch, P. and others},
  title   = {{Masitinib for mild-to-moderate Alzheimer's disease: results from a randomized, placebo-controlled, phase 3, clinical trial}},
  journal = {Alzheimer's research \& therapy},
  year    = {2023},
  doi     = {10.1186/s13195-023-01169-x},
  pmid    = {36849969},
  url     = {https://doi.org/10.1186/s13195-023-01169-x}
}

@article{atte2023-36641664,
  author  = {Atte, Rahkonen and Heidi, Taipale and Marjaana, Koponen and Sirpa, Hartikainen and Anna-Maija, Tolppanen and Antti, Tanskanen and Miia, Tiihonen},
  title   = {{The Cumulative Use of Muscle Relaxants and the Risk of Alzheimer's Disease: A Nationwide Case-Control Study}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2023},
  doi     = {10.3233/JAD-220409},
  pmid    = {36641664},
  url     = {https://doi.org/10.3233/JAD-220409}
}

@article{saleh2023-36624497,
  author  = {Saleh, R. N. M. and Hornberger, M. and Ritchie, C. W. and Minihane, A. M.},
  title   = {{Hormone replacement therapy is associated with improved cognition and larger brain volumes in at-risk APOE4 women: results from the European Prevention of Alzheimer's Disease (EPAD) cohort}},
  journal = {Alzheimer's research \& therapy},
  year    = {2023},
  doi     = {10.1186/s13195-022-01121-5},
  pmid    = {36624497},
  url     = {https://doi.org/10.1186/s13195-022-01121-5}
}

@article{study2023-149a0541,
  title   = {{FDA Approves LEQEMBI (lecanemab-irmb) Under the Accelerated Approval Pathway for the Treatment of Alzheimer's Disease}},
  journal = {U.S. Food and Drug Administration (announced via Biogen press release)},
  year    = {2023}
}

@article{vandyck2023-22dd8fce,
  author  = {van Dyck, C. H. and Swanson, C. J. and Aisen, P. and Bateman, R. J. and Chen, C. and Gee, M. and Kanekiyo, M. and Li, D. and Reyderman, L. and Cohen, S. and Froelich, L. and Katayama, S. and Sabbagh, M. and Vellas, B. and Watson, D. and Dhadda, S. and Irizarry, M. and Kramer, L. D. and Iwatsubo, T.},
  title   = {{Lecanemab in Early Alzheimer's Disease}},
  journal = {New England Journal of Medicine},
  year    = {2023},
  pmid    = {36449413}
}

@article{marcum2023-36598787,
  author  = {Marcum, Z. A. and Gabriel, N. and Bress, A. P. and Hernandez, I.},
  title   = {{Association of New Use of Antihypertensives That Stimulate vs Inhibit Type 2 and 4 Angiotensin II Receptors With Dementia Among Medicare Beneficiaries}},
  journal = {JAMA network open},
  year    = {2023},
  doi     = {10.1001/jamanetworkopen.2022.49370},
  pmid    = {36598787},
  url     = {https://doi.org/10.1001/jamanetworkopen.2022.49370}
}

@article{oosthoek2023-37874087,
  author  = {Oosthoek, M. and Lili, A. and Almeida, A. and van Loosbroek, O. and van der Geest, R. and de Greef-van der Sandt, I. and van Bokhoven, P. and Sikkes, S. A. M. and others},
  title   = {{ASURE Clinical Trial Protocol: A Randomized, Placebo-Controlled, Proof-of-Concept Study Aiming to Evaluate Safety and Target Engagement following Administration of TW001 in Early Alzheimer's Disease Patients}},
  journal = {The journal of prevention of Alzheimer's disease},
  year    = {2023},
  doi     = {10.14283/jpad.2023.107},
  pmid    = {37874087},
  url     = {https://doi.org/10.14283/jpad.2023.107}
}

@article{karima2023-37248896,
  author  = {Karima, S. and Aghamollaii, V. and Mahmoodi Baram, S. and Balenci, L. and Lanctôt, K. L. and Kiss, A. and Tafakhori, A. and Mahdavi, M. and others},
  title   = {{Boswellic Acids Improve Clinical Cognitive Scores and Reduce Systemic Inflammation in Patients with Mild to Moderate Alzheimer's Disease}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2023},
  doi     = {10.3233/jad-221026},
  pmid    = {37248896},
  url     = {https://doi.org/10.3233/jad-221026}
}

@article{desouza2023-35726411,
  author  = {de Souza, M. M. and Cenci, A. R. and Teixeira, K. F. and Machado, V. and Mendes Schuler, M. C. G. and Gonçalves, A. E. and Paula Dalmagro, A. and André Cazarin, C. and others},
  title   = {{DYRK1A Inhibitors and Perspectives for the Treatment of Alzheimer's Disease}},
  journal = {Current medicinal chemistry},
  year    = {2023},
  doi     = {10.2174/0929867329666220620162018},
  pmid    = {35726411},
  url     = {https://doi.org/10.2174/0929867329666220620162018}
}

@article{pontecorvo2022-36251300,
  author  = {Pontecorvo, M. J. and Lu, M. and Burnham, S. C. and Schade, A. E. and Dage, J. L. and Shcherbinin, S. and Collins, E. C. and Sims, JR. and others},
  title   = {{Association of Donanemab Treatment With Exploratory Plasma Biomarkers in Early Symptomatic Alzheimer Disease: A Secondary Analysis of the TRAILBLAZER-ALZ Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2022},
  doi     = {10.1001/jamaneurol.2022.3392},
  pmid    = {36251300},
  url     = {https://doi.org/10.1001/jamaneurol.2022.3392}
}

@article{vandyck2023-36449413,
  author  = {van Dyck, C. H. and Swanson, C. J. and Aisen, P. and Bateman, R. J. and Chen, C. and Gee, M. and Kanekiyo, M. and Li, D. and others},
  title   = {{Lecanemab in Early Alzheimer's Disease}},
  journal = {The New England journal of medicine},
  year    = {2023},
  doi     = {10.1056/nejmoa2212948},
  pmid    = {36449413},
  url     = {https://doi.org/10.1056/nejmoa2212948}
}

@article{ko2022-36399339,
  author  = {Ko, Darae and Lin, Kueiyu Joshua and Bessette, Lily Gui and Lee, Su Been and Walkey, Allan J. and Cheng, Susan C. and Kim, Erin and Glynn, Robert J. and others},
  title   = {{Trends in Use of Oral Anticoagulants in Older Adults With Newly Diagnosed Atrial Fibrillation, 2010-2020}},
  journal = {JAMA Network Open},
  year    = {2022},
  doi     = {10.1001/jamanetworkopen.2022.42964},
  pmid    = {36399339},
  url     = {https://doi.org/10.1001/jamanetworkopen.2022.42964}
}

@article{truong2022-36096687,
  author  = {Truong, C. and Recto, C. and Lafont, C. and Canoui-Poitrine, F. and Belmin, J. B. and Lafuente-Lafuente, C.},
  title   = {{Effect of Cholinesterase Inhibitors on Mortality in Patients With Dementia: A Systematic Review of Randomized and Nonrandomized Trials}},
  journal = {Neurology},
  year    = {2022},
  doi     = {10.1212/wnl.0000000000201161},
  pmid    = {36096687},
  url     = {https://doi.org/10.1212/wnl.0000000000201161}
}

@article{pasquini2022-36367770,
  author  = {Pasquini, S. and Margaritini, A. and Gambella, E. and Di Rosa, M. and Maranesi, E. and Bevilacqua, R. and Civerchia, P. and Pelliccioni, G.},
  title   = {{A Psychosocial Intervention for Supporting Informal Caregivers of Older People With Alzheimer Disease: Protocol for the InnFamiglia Randomized Controlled Trial}},
  journal = {JMIR research protocols},
  year    = {2022},
  doi     = {10.2196/37496},
  pmid    = {36367770},
  url     = {https://doi.org/10.2196/37496}
}

@article{ostrowitzki2022-36121669,
  author  = {Ostrowitzki, S. and Bittner, T. and Sink, K. M. and Mackey, H. and Rabe, C. and Honig, L. S. and Cassetta, E. and Woodward, M. and others},
  title   = {{Evaluating the Safety and Efficacy of Crenezumab vs Placebo in Adults With Early Alzheimer Disease: Two Phase 3 Randomized Placebo-Controlled Trials}},
  journal = {JAMA neurology},
  year    = {2022},
  doi     = {10.1001/jamaneurol.2022.2909},
  pmid    = {36121669},
  url     = {https://doi.org/10.1001/jamaneurol.2022.2909}
}

@article{simko2022-36215904,
  author  = {Šimko, P. and Kent, J. A. and Rektorova, I.},
  title   = {{Is non-invasive brain stimulation effective for cognitive enhancement in Alzheimer's disease? An updated meta-analysis}},
  journal = {Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology},
  year    = {2022},
  doi     = {10.1016/j.clinph.2022.09.010},
  pmid    = {36215904},
  url     = {https://doi.org/10.1016/j.clinph.2022.09.010}
}

@article{alsubaie2022-36291224,
  author  = {Alsubaie, N. and Al-Kuraishy, H. M. and Al-Gareeb, A. I. and Alharbi, B. and De Waard, M. and Sabatier, J. M. and Saad, H. M. and Batiha, G. E.},
  title   = {{Statins Use in Alzheimer Disease: Bane or Boon from Frantic Search and Narrative Review}},
  journal = {Brain sciences},
  year    = {2022},
  doi     = {10.3390/brainsci12101290},
  pmid    = {36291224},
  url     = {https://doi.org/10.3390/brainsci12101290}
}

@article{wang2022-36150665,
  author  = {Wang, L. and Zhang, J. and Guo, C. and He, J. and Zhang, S. and Wang, Y. and Zhao, Y. and Li, L. and others},
  title   = {{The efficacy and safety of transcutaneous auricular vagus nerve stimulation in patients with mild cognitive impairment: A double blinded randomized clinical trial}},
  journal = {Brain stimulation},
  year    = {2022},
  doi     = {10.1016/j.brs.2022.09.003},
  pmid    = {36150665},
  url     = {https://doi.org/10.1016/j.brs.2022.09.003}
}

@article{marin2022-36094804,
  author  = {Marin, A. and DeCaro, R. and Schiloski, K. and Elshaar, A. and Dwyer, B. and Vives-Rodriguez, A. and Palumbo, R. and Turk, K. and others},
  title   = {{Home-Based Electronic Cognitive Therapy in Patients With Alzheimer Disease: Feasibility Randomized Controlled Trial}},
  journal = {JMIR formative research},
  year    = {2022},
  doi     = {10.2196/34450},
  pmid    = {36094804},
  url     = {https://doi.org/10.2196/34450}
}

@article{teng2022-35696185,
  author  = {Teng, E. and Manser, P. T. and Pickthorn, K. and Brunstein, F. and Blendstrup, M. and Sanabria Bohorquez, S. and Wildsmith, K. R. and Toth, B. and others},
  title   = {{Safety and Efficacy of Semorinemab in Individuals With Prodromal to Mild Alzheimer Disease: A Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2022},
  doi     = {10.1001/jamaneurol.2022.1375},
  pmid    = {35696185},
  url     = {https://doi.org/10.1001/jamaneurol.2022.1375}
}

@article{basheer2022-35612544,
  author  = {Basheer, A. and Agarwal, A. and Mishra, B. and Gupta, A. and Padma Srivastava, M. V. and Kirubakaran, R. and Vishnu, V.},
  title   = {{Use of Bacopa monnieri in the Treatment of Dementia Due to Alzheimer Disease: Systematic Review of Randomized Controlled Trials}},
  journal = {Interactive journal of medical research},
  year    = {2022},
  doi     = {10.2196/38542},
  pmid    = {35612544},
  url     = {https://doi.org/10.2196/38542}
}

@article{flo2022-35771851,
  author  = {Flo, B. K. and Matziorinis, A. M. and Skouras, S. and Sudmann, T. T. and Gold, C. and Koelsch, S.},
  title   = {{Study protocol for the Alzheimer and music therapy study: An RCT to compare the efficacy of music therapy and physical activity on brain plasticity, depressive symptoms, and cognitive decline, in a population with and at risk for Alzheimer's disease}},
  journal = {PloS one},
  year    = {2022},
  doi     = {10.1371/journal.pone.0270682},
  pmid    = {35771851},
  url     = {https://doi.org/10.1371/journal.pone.0270682}
}

@article{yao2022-35700915,
  author  = {Yao, Q. and Tang, F. and Wang, Y. and Yan, Y. and Dong, L. and Wang, T. and Zhu, D. and Tian, M. and others},
  title   = {{Effect of cerebellum stimulation on cognitive recovery in patients with Alzheimer disease: A randomized clinical trial}},
  journal = {Brain stimulation},
  year    = {2022},
  doi     = {10.1016/j.brs.2022.06.004},
  pmid    = {35700915},
  url     = {https://doi.org/10.1016/j.brs.2022.06.004}
}

@article{ross2022-35344024,
  author  = {Ross, E. L. and Weinberg, M. S. and Arnold, S. E.},
  title   = {{Cost-effectiveness of Aducanumab and Donanemab for Early Alzheimer Disease in the US}},
  journal = {JAMA neurology},
  year    = {2022},
  doi     = {10.1001/jamaneurol.2022.0315},
  pmid    = {35344024},
  url     = {https://doi.org/10.1001/jamaneurol.2022.0315}
}

@article{ross2022-b0c356d3,
  author  = {Ross, E. L. and Weinberg, M. S. and Arnold, S. E.},
  title   = {{Cost-effectiveness of Aducanumab and Donanemab for Early Alzheimer Disease in the US}},
  journal = {JAMA Neurology},
  year    = {2022},
  pmid    = {35344024}
}

@article{anne2022-35321876,
  author  = {Anne, Bénard-Laribière and Emilie, Hucteau and Stéphanie, Debette and Julien, Kirchgesner and Julien, Bezin and Antoine, Pariente},
  title   = {{Risk of first ischaemic stroke and use of antidopaminergic antiemetics: nationwide case-time-control study}},
  journal = {BMJ (Clinical research ed.)},
  year    = {2022},
  doi     = {10.1136/bmj-2021-066192},
  pmid    = {35321876},
  url     = {https://doi.org/10.1136/bmj-2021-066192}
}

@article{andrade2022-35339351,
  author  = {Andrade, S. M. and Machado, D. G. D. S. and Silva-Sauerc, L. D. and Regis, C. T. and Mendes, C. K. T. T. and de Araújo, J. S. S. and de Araújo, K. D. T. and Costa, L. P. and others},
  title   = {{Effects of multisite anodal transcranial direct current stimulation combined with cognitive stimulation in patients with Alzheimer's disease and its neurophysiological correlates: A double-blind randomized clinical trial}},
  journal = {Neurophysiologie clinique = Clinical neurophysiology},
  year    = {2022},
  doi     = {10.1016/j.neucli.2022.02.003},
  pmid    = {35339351},
  url     = {https://doi.org/10.1016/j.neucli.2022.02.003}
}

@article{sanchezperez2022-35327020,
  author  = {Sánchez-Pérez, A. and Mendialdua-Canales, D. and Hurtado-Pomares, M. and Peral-Gómez, P. and Juárez-Leal, I. and Espinosa-Sempere, C. and Fernández-Pires, P. and Zango-Martín, I. and others},
  title   = {{The ATENción Plena en Enfermedad de Alzheimer (ATENEA-Mindfulness in Alzheimer's Disease) Program for Caregivers: Study Protocol for a Randomized Controlled Trial}},
  journal = {Healthcare (Basel, Switzerland)},
  year    = {2022},
  doi     = {10.3390/healthcare10030542},
  pmid    = {35327020},
  url     = {https://doi.org/10.3390/healthcare10030542}
}

@article{day2022-35197360,
  author  = {Day, G. S. and Scarmeas, N. and Dubinsky, R. and Coerver, K. and Mostacero, A. and West, B. and Wessels, SR. and Armstrong, M. J.},
  title   = {{Aducanumab Use in Symptomatic Alzheimer Disease Evidence in Focus [RETIRED]: A Report of the AAN Guidelines Subcommittee}},
  journal = {Neurology},
  year    = {2022},
  doi     = {10.1212/wnl.0000000000200176},
  pmid    = {35197360},
  url     = {https://doi.org/10.1212/wnl.0000000000200176}
}

@article{ayoub2022-35137748,
  author  = {Ayoub, I. M. and George, M. Y. and Menze, E. T. and Mahmoud, M. and Botros, M. and Essam, M. and Ashmawy, I. and Shendi, P. and others},
  title   = {{Insights into the neuroprotective effects of Salvia officinalis L. and Salvia microphylla Kunth in the memory impairment rat model}},
  journal = {Food \& function},
  year    = {2022},
  doi     = {10.1039/d1fo02988f},
  pmid    = {35137748},
  url     = {https://doi.org/10.1039/d1fo02988f}
}

@article{yang2022-35265207,
  author  = {Yang, L. and Wu, C. and Parker, E. and Li, Y. and Dong, Y. and Tucker, L. and Brann, D. W. and Lin, H. W. and others},
  title   = {{Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model}},
  journal = {Theranostics},
  year    = {2022},
  doi     = {10.7150/thno.70756},
  pmid    = {35265207},
  url     = {https://doi.org/10.7150/thno.70756}
}

@article{whittington2022-35022306,
  author  = {Whittington, M. D. and Campbell, J. D. and Rind, D. and Fluetsch, N. and Lin, G. A. and Pearson, S. D.},
  title   = {{Cost-Effectiveness and Value-Based Pricing of Aducanumab for Patients With Early Alzheimer Disease}},
  journal = {Neurology},
  year    = {2022},
  doi     = {10.1212/wnl.0000000000013314},
  pmid    = {35022306},
  url     = {https://doi.org/10.1212/wnl.0000000000013314}
}

@article{buddhaeberlein2022-35542991,
  author  = {Budd Haeberlein, S. and Aisen, P. S. and Barkhof, F. and Chalkias, S. and Chen, T. and Cohen, S. and Dent, G. and Hansson, O. and others},
  title   = {{Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer's Disease}},
  journal = {The journal of prevention of Alzheimer's disease},
  year    = {2022},
  doi     = {10.14283/jpad.2022.30},
  pmid    = {35542991},
  url     = {https://doi.org/10.14283/jpad.2022.30}
}

@article{sveikata2022-34905943,
  author  = {Sveikata, L. and Charidimou, A. and Viswanathan, A.},
  title   = {{Vessels Sing Their ARIAs: The Role of Vascular Amyloid in the Age of Aducanumab}},
  journal = {Stroke},
  year    = {2022},
  doi     = {10.1161/strokeaha.121.036873},
  pmid    = {34905943},
  url     = {https://doi.org/10.1161/strokeaha.121.036873}
}

@article{bagorozankovic2021-34851866,
  author  = {Bago Rožanković, P. and Rožanković, M. and Badžak, J. and Stojić, M. and Šušak Sporiš, I.},
  title   = {{Impact of Donepezil and Memantine on Behavioral and Psychological Symptoms of Alzheimer Disease: Six-month Open-label Study}},
  journal = {Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology},
  year    = {2021},
  doi     = {10.1097/wnn.0000000000000285},
  pmid    = {34851866},
  url     = {https://doi.org/10.1097/wnn.0000000000000285}
}

@article{cheng2022-34843329,
  author  = {Cheng, S. T. and Chan, W. C. and Fung, H. H. and Lam, L. C. W.},
  title   = {{Self-efficacy in controlling upsetting thoughts, but not positive gains, mediates the effects of benefit-finding group intervention for Alzheimer family caregivers}},
  journal = {Psychology and aging},
  year    = {2022},
  doi     = {10.1037/pag0000654},
  pmid    = {34843329},
  url     = {https://doi.org/10.1037/pag0000654}
}

@article{vossel2021-34570177,
  author  = {Vossel, K. and Ranasinghe, K. G. and Beagle, A. J. and La, A. and Ah Pook, K. and Castro, M. and Mizuiri, D. and Honma, S. M. and others},
  title   = {{Effect of Levetiracetam on Cognition in Patients With Alzheimer Disease With and Without Epileptiform Activity: A Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2021},
  doi     = {10.1001/jamaneurol.2021.3310},
  pmid    = {34570177},
  url     = {https://doi.org/10.1001/jamaneurol.2021.3310}
}

@article{mintzer2021-34570180,
  author  = {Mintzer, J. and Lanctôt, K. L. and Scherer, R. W. and Rosenberg, P. B. and Herrmann, N. and van Dyck, C. H. and Padala, P. R. and Brawman-Mintzer, O. and others},
  title   = {{Effect of Methylphenidate on Apathy in Patients With Alzheimer Disease: The ADMET 2 Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2021},
  doi     = {10.1001/jamaneurol.2021.3356},
  pmid    = {34570180},
  url     = {https://doi.org/10.1001/jamaneurol.2021.3356}
}

@article{chiungchih2021-34506009,
  author  = {Chiung-Chih, Chang and Lung, Chan and Hsi-Hsien, Chou and Yu-Wan, Yang and Ta-Fu, Chen and Ting-Bin, Chen and Chin-I, Chen and Audrey, Yang and others},
  title   = {{Effectiveness of the 10 cm2 Rivastigmine Patch in Taiwanese Patients with Mild-to-Moderate Alzheimer's Dementia: A 48-Week Real-World Observational Study}},
  journal = {Advances in therapy},
  year    = {2021},
  doi     = {10.1007/s12325-021-01893-6},
  pmid    = {34506009},
  url     = {https://doi.org/10.1007/s12325-021-01893-6}
}

@article{mitchell2021-34251396,
  author  = {Mitchell, S. L. and D'Agata, E. M. C. and Hanson, L. C. and Loizeau, A. J. and Habtemariam, D. A. and Tsai, T. and Anderson, R. A. and Shaffer, M. L.},
  title   = {{The Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer Disease and Other Dementias (TRAIN-AD): A Cluster Randomized Clinical Trial}},
  journal = {JAMA internal medicine},
  year    = {2021},
  doi     = {10.1001/jamainternmed.2021.3098},
  pmid    = {34251396},
  url     = {https://doi.org/10.1001/jamainternmed.2021.3098}
}

@article{gu2021-34402024,
  author  = {Gu, J. and Li, Z. and Chen, H. and Xu, X. and Li, Y. and Gui, Y.},
  title   = {{Neuroprotective Effect of Trans-Resveratrol in Mild to Moderate Alzheimer Disease: A Randomized, Double-Blind Trial}},
  journal = {Neurology and therapy},
  year    = {2021},
  doi     = {10.1007/s40120-021-00271-2},
  pmid    = {34402024},
  url     = {https://doi.org/10.1007/s40120-021-00271-2}
}

@article{moussavi2021-34383681,
  author  = {Moussavi, Z. and Koski, L. and Fitzgerald, P. B. and Millikin, C. and Lithgow, B. and Jafari-Jozani, M. and Wang, X.},
  title   = {{Repeated Transcranial Magnetic Stimulation for Improving Cognition in Alzheimer Disease: Protocol for an Interim Analysis of a Randomized Controlled Trial}},
  journal = {JMIR research protocols},
  year    = {2021},
  doi     = {10.2196/31183},
  pmid    = {34383681},
  url     = {https://doi.org/10.2196/31183}
}

@article{duruasiret2021-34233376,
  author  = {Duru Aşiret, G. and Kütmeç Yılmaz, C. and Sayın Kasar, K.},
  title   = {{Investigation of the effects of interventions made according to the Progressively Lowered Stress Threshold Model on the care outcomes of Alzheimer patients and their families: a randomized clinical trial}},
  journal = {Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society},
  year    = {2021},
  doi     = {10.1111/psyg.12734},
  pmid    = {34233376},
  url     = {https://doi.org/10.1111/psyg.12734}
}

@article{fleckleonard2021-34156732,
  author  = {Fleck Leonard, M.},
  title   = {{Alzheimer's and Aducanumab: Unjust Profits and False Hopes}},
  journal = {The Hastings Center report},
  year    = {2021},
  doi     = {10.1002/hast.1264},
  pmid    = {34156732},
  url     = {https://doi.org/10.1002/hast.1264}
}

@article{study2021-18854f0d,
  title   = {{FDA Grants Accelerated Approval for ADUHELM (aducanumab) as the First and Only Alzheimer's Disease Treatment to Address a Defining Pathology of the Disease}},
  journal = {U.S. Food and Drug Administration (announced via Biogen press release)},
  year    = {2021}
}

@article{prins2021-34044875,
  author  = {Prins, N. D. and Harrison, J. E. and Chu, H. M. and Blackburn, K. and Alam, J. J. and Scheltens, P. and {REVERSE-SD Study Investigators}},
  title   = {{A phase 2 double-blind placebo-controlled 24-week treatment clinical study of the p38 alpha kinase inhibitor neflamapimod in mild Alzheimer's disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2021},
  doi     = {10.1186/s13195-021-00843-2},
  pmid    = {34044875},
  url     = {https://doi.org/10.1186/s13195-021-00843-2}
}

@article{swanson2021-33865446,
  author  = {Swanson, C. J. and Zhang, Y. and Dhadda, S. and Wang, J. and Kaplow, J. and Lai, R. Y. K. and Lannfelt, L. and Bradley, H. and others},
  title   = {{A randomized, double-blind, phase 2b proof-of-concept clinical trial in early Alzheimer's disease with lecanemab, an anti-Aβ protofibril antibody}},
  journal = {Alzheimer's research \& therapy},
  year    = {2021},
  doi     = {10.1186/s13195-021-00813-8},
  pmid    = {33865446},
  url     = {https://doi.org/10.1186/s13195-021-00813-8}
}

@article{leinenga2021-33836798,
  author  = {Leinenga, G. and Koh, W. K. and Götz, J.},
  title   = {{A comparative study of the effects of Aducanumab and scanning ultrasound on amyloid plaques and behavior in the APP23 mouse model of Alzheimer disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2021},
  doi     = {10.1186/s13195-021-00809-4},
  pmid    = {33836798},
  url     = {https://doi.org/10.1186/s13195-021-00809-4}
}

@article{lin2021-33881530,
  author  = {Lin, C. H. and Chen, P. K. and Wang, S. H. and Lane, H. Y.},
  title   = {{Effect of Sodium Benzoate on Cognitive Function Among Patients With Behavioral and Psychological Symptoms of Dementia: Secondary Analysis of a Randomized Clinical Trial}},
  journal = {JAMA network open},
  year    = {2021},
  doi     = {10.1001/jamanetworkopen.2021.6156},
  pmid    = {33881530},
  url     = {https://doi.org/10.1001/jamanetworkopen.2021.6156}
}

@article{xu2021-33741639,
  author  = {Xu, H. and Garcia-Ptacek, S. and Jönsson, L. and Wimo, A. and Nordström, P. and Eriksdotter, M.},
  title   = {{Long-term Effects of Cholinesterase Inhibitors on Cognitive Decline and Mortality}},
  journal = {Neurology},
  year    = {2021},
  doi     = {10.1212/wnl.0000000000011832},
  pmid    = {33741639},
  url     = {https://doi.org/10.1212/wnl.0000000000011832}
}

@article{xiao2021-33731209,
  author  = {Xiao, S. and Chan, P. and Wang, T. and Hong, Z. and Wang, S. and Kuang, W. and He, J. and Pan, X. and others},
  title   = {{A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer's dementia}},
  journal = {Alzheimer's research \& therapy},
  year    = {2021},
  doi     = {10.1186/s13195-021-00795-7},
  pmid    = {33731209},
  url     = {https://doi.org/10.1186/s13195-021-00795-7}
}

@article{mintun2021-33720637,
  author  = {Mintun, M. A. and Lo, A. C. and Duggan Evans, C. and Wessels, A. M. and Ardayfio, P. A. and Andersen, S. W. and Shcherbinin, S. and Sparks, J. and others},
  title   = {{Donanemab in Early Alzheimer's Disease}},
  journal = {The New England journal of medicine},
  year    = {2021},
  doi     = {10.1056/nejmoa2100708},
  pmid    = {33720637},
  url     = {https://doi.org/10.1056/nejmoa2100708}
}

@article{sperling2021-33464300,
  author  = {Sperling, R. and Henley, D. and Aisen, P. S. and Raman, R. and Donohue, M. C. and Ernstrom, K. and Rafii, M. S. and Streffer, J. and others},
  title   = {{Findings of Efficacy, Safety, and Biomarker Outcomes of Atabecestat in Preclinical Alzheimer Disease: A Truncated Randomized Phase 2b/3 Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2021},
  doi     = {10.1001/jamaneurol.2020.4857},
  pmid    = {33464300},
  url     = {https://doi.org/10.1001/jamaneurol.2020.4857}
}

@article{phillips2021-33622392,
  author  = {Phillips, M. C. L. and Deprez, L. M. and Mortimer, G. M. N. and Murtagh, D. K. J. and McCoy, S. and Mylchreest, R. and Gilbertson, L. J. and Clark, K. M. and others},
  title   = {{Randomized crossover trial of a modified ketogenic diet in Alzheimer's disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2021},
  doi     = {10.1186/s13195-021-00783-x},
  pmid    = {33622392},
  url     = {https://doi.org/10.1186/s13195-021-00783-x}
}

@article{battle2021-33704781,
  author  = {Battle, C. E. and Abdul-Rahim, A. H. and Shenkin, S. D. and Hewitt, J. and Quinn, T. J.},
  title   = {{Cholinesterase inhibitors for vascular dementia and other vascular cognitive impairments: a network meta-analysis}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2021},
  doi     = {10.1002/14651858.cd013306.pub2},
  pmid    = {33704781},
  url     = {https://doi.org/10.1002/14651858.cd013306.pub2}
}

@article{cezar2021-33586858,
  author  = {Cezar, N. O. C. and Ansai, J. H. and de Andrade, L. P.},
  title   = {{Home-based multimodal exercise program in older people with Alzheimer disease: Randomized controlled trial protocol}},
  journal = {Physiotherapy research international : the journal for researchers and clinicians in physical therapy},
  year    = {2021},
  doi     = {10.1002/pri.1899},
  pmid    = {33586858},
  url     = {https://doi.org/10.1002/pri.1899}
}

@article{moussavi2021-33416500,
  author  = {Moussavi, Z. and Rutherford, G. and Lithgow, B. and Millikin, C. and Modirrousta, M. and Mansouri, B. and Wang, X. and Omelan, C. and others},
  title   = {{Repeated Transcranial Magnetic Stimulation for Improving Cognition in Patients With Alzheimer Disease: Protocol for a Randomized, Double-Blind, Placebo-Controlled Trial}},
  journal = {JMIR research protocols},
  year    = {2021},
  doi     = {10.2196/25144},
  pmid    = {33416500},
  url     = {https://doi.org/10.2196/25144}
}

@article{leinenga2021-a9983515,
  author  = {Leinenga, G. and Koh, W. K. and Götz, J.},
  title   = {{A comparative study of the effects of Aducanumab and scanning ultrasound on amyloid plaques and behavior in the APP23 mouse model of Alzheimer disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2021},
  doi     = {10.1101/2021.01.04.425327},
  url     = {https://doi.org/10.1101/2021.01.04.425327}
}

@article{hoilundcarlsen2021-34657891,
  author  = {Høilund-Carlsen, P. F. and Alavi, A.},
  title   = {{Aducanumab (Marketed as Aduhelm) Approval Is Likely Based on Misinterpretation of PET Imaging Data}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2021},
  doi     = {10.3233/jad-215275},
  pmid    = {34657891},
  url     = {https://doi.org/10.3233/jad-215275}
}

@article{sugimoto2021-34585222,
  author  = {Sugimoto, T. and Sakurai, T. and Akatsu, H. and Doi, T. and Fujiwara, Y. and Hirakawa, A. and Kinoshita, F. and Kuzuya, M. and others},
  title   = {{The Japan-Multimodal Intervention Trial for Prevention of Dementia (J-MINT): The Study Protocol for an 18-Month, Multicenter, Randomized, Controlled Trial}},
  journal = {The journal of prevention of Alzheimer's disease},
  year    = {2021},
  doi     = {10.14283/jpad.2021.29},
  pmid    = {34585222},
  url     = {https://doi.org/10.14283/jpad.2021.29}
}

@article{kandiah2021-33352000,
  author  = {Kandiah, N. and Chan, Y. F. and Chen, C. and Dasig, D. and Dominguez, J. and Han, S. H. and Jia, J. and Kim, S. and others},
  title   = {{Strategies for the use of Ginkgo biloba extract, EGb 761® , in the treatment and management of mild cognitive impairment in Asia: Expert consensus}},
  journal = {CNS neuroscience \& therapeutics},
  year    = {2021},
  doi     = {10.1111/cns.13536},
  pmid    = {33352000},
  url     = {https://doi.org/10.1111/cns.13536}
}

@article{kim2021-33332107,
  author  = {Kim, D. and Bae, G. H. and Kim, H. Y. and Jeon, H. and Kim, K. and Shin, J. and Lee, S. and Hong, S. and others},
  title   = {{Orally Administered Benzofuran Derivative Disaggregated Aβ Plaques and Oligomers in the Brain of 5XFAD Alzheimer Transgenic Mouse}},
  journal = {ACS chemical neuroscience},
  year    = {2021},
  doi     = {10.1021/acschemneuro.0c00606},
  pmid    = {33332107},
  url     = {https://doi.org/10.1021/acschemneuro.0c00606}
}

@article{blackman2021-33289311,
  author  = {Blackman, J. and Swirski, M. and Clynes, J. and Harding, S. and Leng, Y. and Coulthard, E.},
  title   = {{Pharmacological and non-pharmacological interventions to enhance sleep in mild cognitive impairment and mild Alzheimer's disease: A systematic review}},
  journal = {Journal of sleep research},
  year    = {2021},
  doi     = {10.1111/jsr.13229},
  pmid    = {33289311},
  url     = {https://doi.org/10.1111/jsr.13229}
}

@article{carter2020-26f00cc1,
  author  = {Carter, Elizabeth Jeanne and Tan, Erwin J.},
  title   = {{Concomitant Cholinesterase Inhibitor and Anticholinergic Drug Use Among Older Adults With Dementia}},
  journal = {Innovation in Aging},
  year    = {2020},
  doi     = {10.1093/geroni/igaa057.842},
  url     = {https://doi.org/10.1093/geroni/igaa057.842}
}

@article{kalayc2021-33155700,
  author  = {Kalaycı, M. and Türkeş, C. and Arslan, M. and Demir, Y. and Ş, Beydemir},
  title   = {{Novel benzoic acid derivatives: Synthesis and biological evaluation as multitarget acetylcholinesterase and carbonic anhydrase inhibitors}},
  journal = {Archiv der Pharmazie},
  year    = {2021},
  doi     = {10.1002/ardp.202000282},
  pmid    = {33155700},
  url     = {https://doi.org/10.1002/ardp.202000282}
}

@article{berk2020-32492080,
  author  = {Berk, M. and Woods, R. L. and Nelson, M. R. and Shah, R. C. and Reid, C. M. and Storey, E. and Fitzgerald, S. and Lockery, J. E. and others},
  title   = {{Effect of Aspirin vs Placebo on the Prevention of Depression in Older People: A Randomized Clinical Trial}},
  journal = {JAMA psychiatry},
  year    = {2020},
  doi     = {10.1001/jamapsychiatry.2020.1214},
  pmid    = {32492080},
  url     = {https://doi.org/10.1001/jamapsychiatry.2020.1214}
}

@article{bagattini2020-33002645,
  author  = {Bagattini, C. and Zanni, M. and Barocco, F. and Caffarra, P. and Brignani, D. and Miniussi, C. and Defanti, C. A.},
  title   = {{Enhancing cognitive training effects in Alzheimer's disease: rTMS as an add-on treatment}},
  journal = {Brain stimulation},
  year    = {2020},
  doi     = {10.1016/j.brs.2020.09.010},
  pmid    = {33002645},
  url     = {https://doi.org/10.1016/j.brs.2020.09.010}
}

@article{anstey2020-32969833,
  author  = {Anstey, K. J. and Cherbuin, N. and Kim, S. and McMaster, M. and D'Este, C. and Lautenschlager, N. and Rebok, G. and McRae, I. and others},
  title   = {{An Internet-Based Intervention Augmented With a Diet and Physical Activity Consultation to Decrease the Risk of Dementia in At-Risk Adults in a Primary Care Setting: Pragmatic Randomized Controlled Trial}},
  journal = {Journal of medical Internet research},
  year    = {2020},
  doi     = {10.2196/19431},
  pmid    = {32969833},
  url     = {https://doi.org/10.2196/19431}
}

@article{shippy2020-32958021,
  author  = {Shippy, D. C. and Wilhelm, C. and Viharkumar, P. A. and Raife, T. J. and Ulland, T. K.},
  title   = {{β-Hydroxybutyrate inhibits inflammasome activation to attenuate Alzheimer's disease pathology}},
  journal = {Journal of neuroinflammation},
  year    = {2020},
  doi     = {10.1186/s12974-020-01948-5},
  pmid    = {32958021},
  url     = {https://doi.org/10.1186/s12974-020-01948-5}
}

@article{craft2020-32568367,
  author  = {Craft, S. and Raman, R. and Chow, T. W. and Rafii, M. S. and Sun, C. K. and Rissman, R. A. and Donohue, M. C. and Brewer, J. B. and others},
  title   = {{Safety, Efficacy, and Feasibility of Intranasal Insulin for the Treatment of Mild Cognitive Impairment and Alzheimer Disease Dementia: A Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2020},
  doi     = {10.1001/jamaneurol.2020.1840},
  pmid    = {32568367},
  url     = {https://doi.org/10.1001/jamaneurol.2020.1840}
}

@article{kainuma2020-32957414,
  author  = {Kainuma, M. and Funakoshi, K. and Ouma, S. and Yamashita, K. I. and Ohara, T. and Yoshiiwa, A. and Murata, M. and Tsuboi, Y.},
  title   = {{The efficacy and safety of hachimijiogan for mild Alzheimer disease in an exploratory, open standard treatment controlled, randomized allocation, multicenter trial: A study protocol}},
  journal = {Medicine},
  year    = {2020},
  doi     = {10.1097/md.0000000000022370},
  pmid    = {32957414},
  url     = {https://doi.org/10.1097/md.0000000000022370}
}

@article{tolar2020-32787971,
  author  = {Tolar, M. and Abushakra, S. and Hey, J. A. and Porsteinsson, A. and Sabbagh, M.},
  title   = {{Aducanumab, gantenerumab, BAN2401, and ALZ-801-the first wave of amyloid-targeting drugs for Alzheimer's disease with potential for near term approval}},
  journal = {Alzheimer's research \& therapy},
  year    = {2020},
  doi     = {10.1186/s13195-020-00663-w},
  pmid    = {32787971},
  url     = {https://doi.org/10.1186/s13195-020-00663-w}
}

@article{duggleby2020-32778059,
  author  = {Duggleby, W. and O'Rourke, H. and Swindle, J. and Peacock, S. and McAiney, C. and Baxter, P. and Thompson, G. and Dubé, V. and others},
  title   = {{Study protocol: pragmatic randomized control trial of my tools 4 care- in care (MT4C-in care) a web-based tool for family Carers of persons with dementia residing in long term care}},
  journal = {BMC geriatrics},
  year    = {2020},
  doi     = {10.1186/s12877-020-01690-w},
  pmid    = {32778059},
  url     = {https://doi.org/10.1186/s12877-020-01690-w}
}

@article{lee2020-32872063,
  author  = {Lee, J. and Jin, C. and Cho, S. Y. and Park, S. U. and Jung, W. S. and Moon, S. K. and Park, J. M. and Ko, C. N. and others},
  title   = {{Herbal medicine treatment for Alzheimer disease: A protocol for a systematic review and meta-analysis}},
  journal = {Medicine},
  year    = {2020},
  doi     = {10.1097/md.0000000000021745},
  pmid    = {32872063},
  url     = {https://doi.org/10.1097/md.0000000000021745}
}

@article{boada2020-32715623,
  author  = {Boada, M. and López, O. L. and Olazarán, J. and Núñez, L. and Pfeffer, M. and Paricio, M. and Lorites, J. and Piñol-Ripoll, G. and others},
  title   = {{A randomized, controlled clinical trial of plasma exchange with albumin replacement for Alzheimer's disease: Primary results of the AMBAR Study}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2020},
  doi     = {10.1002/alz.12137},
  pmid    = {32715623},
  url     = {https://doi.org/10.1002/alz.12137}
}

@article{arellanes2020-32690472,
  author  = {Arellanes, I. C. and Choe, N. and Solomon, V. and He, X. and Kavin, B. and Martinez, A. E. and Kono, N. and Buennagel, D. P. and others},
  title   = {{Brain delivery of supplemental docosahexaenoic acid (DHA): A randomized placebo-controlled clinical trial}},
  journal = {EBioMedicine},
  year    = {2020},
  doi     = {10.1016/j.ebiom.2020.102883},
  pmid    = {32690472},
  url     = {https://doi.org/10.1016/j.ebiom.2020.102883}
}

@article{koch2020-32667654,
  author  = {Koch, G. and Motta, C. and Bonnì, S. and Pellicciari, M. C. and Picazio, S. and Casula, E. P. and Maiella, M. and Di Lorenzo, F. and others},
  title   = {{Effect of Rotigotine vs Placebo on Cognitive Functions Among Patients With Mild to Moderate Alzheimer Disease: A Randomized Clinical Trial}},
  journal = {JAMA network open},
  year    = {2020},
  doi     = {10.1001/jamanetworkopen.2020.10372},
  pmid    = {32667654},
  url     = {https://doi.org/10.1001/jamanetworkopen.2020.10372}
}

@article{lee2020-32714142,
  author  = {Lee, Y. F. and Gerashchenko, D. and Timofeev, I. and Bacskai, B. J. and Kastanenka, K. V.},
  title   = {{Slow Wave Sleep Is a Promising Intervention Target for Alzheimer's Disease}},
  journal = {Frontiers in neuroscience},
  year    = {2020},
  doi     = {10.3389/fnins.2020.00705},
  pmid    = {32714142},
  url     = {https://doi.org/10.3389/fnins.2020.00705}
}

@article{giudici2020-33036701,
  author  = {Giudici, K. V. and de Souto Barreto, P. and Beard, J. and Cantet, C. and Araujo de Carvalho, I. and Rolland, Y. and Vellas, B. and {MAPT DSA group}},
  title   = {{Effect of long-term omega-3 supplementation and a lifestyle multidomain intervention on intrinsic capacity among community-dwelling older adults: Secondary analysis of a randomized, placebo-controlled trial (MAPT study)}},
  journal = {Maturitas},
  year    = {2020},
  doi     = {10.1016/j.maturitas.2020.06.012},
  pmid    = {33036701},
  url     = {https://doi.org/10.1016/j.maturitas.2020.06.012}
}

@article{watt2020-32546202,
  author  = {Watt, J. A. and Goodarzi, Z. and Veroniki, A. A. and Nincic, V. and Khan, P. A. and Ghassemi, M. and Thompson, Y. and Lai, Y. and others},
  title   = {{Safety of pharmacologic interventions for neuropsychiatric symptoms in dementia: a systematic review and network meta-analysis}},
  journal = {BMC geriatrics},
  year    = {2020},
  doi     = {10.1186/s12877-020-01607-7},
  pmid    = {32546202},
  url     = {https://doi.org/10.1186/s12877-020-01607-7}
}

@article{turner2020-32468646,
  author  = {Turner, R. S. and Hebron, M. L. and Lawler, A. and Mundel, E. E. and Yusuf, N. and Starr, J. N. and Anjum, M. and Pagan, F. and others},
  title   = {{Nilotinib Effects on Safety, Tolerability, and Biomarkers in Alzheimer's Disease}},
  journal = {Annals of neurology},
  year    = {2020},
  doi     = {10.1002/ana.25775},
  pmid    = {32468646},
  url     = {https://doi.org/10.1002/ana.25775}
}

@article{paunescu2020-32118591,
  author  = {Paunescu, H. and Dima, L. and Ghita, I. and Coman, L. and Ifteni, P. I. and Fulga, I. and Coman, O. A.},
  title   = {{A Systematic Review of Clinical Studies on the Effect of Psychoactive Cannabinoids in Psychiatric Conditions in Alzheimer Dementia}},
  journal = {American journal of therapeutics},
  year    = {2020},
  doi     = {10.1097/mjt.0000000000001120},
  pmid    = {32118591},
  url     = {https://doi.org/10.1097/mjt.0000000000001120}
}

@article{maier2020-32463470,
  author  = {Maier, F. and Spottke, A. and Bach, J. P. and Bartels, C. and Buerger, K. and Dodel, R. and Fellgiebel, A. and Fliessbach, K. and others},
  title   = {{Bupropion for the Treatment of Apathy in Alzheimer Disease: A Randomized Clinical Trial}},
  journal = {JAMA network open},
  year    = {2020},
  doi     = {10.1001/jamanetworkopen.2020.6027},
  pmid    = {32463470},
  url     = {https://doi.org/10.1001/jamanetworkopen.2020.6027}
}

@article{ryan2020-32213642,
  author  = {Ryan, J. and Storey, E. and Murray, A. M. and Woods, R. L. and Wolfe, R. and Reid, C. M. and Nelson, M. R. and Chong, T. T. J. and others},
  title   = {{Randomized placebo-controlled trial of the effects of aspirin on dementia and cognitive decline}},
  journal = {Neurology},
  year    = {2020},
  doi     = {10.1212/wnl.0000000000009277},
  pmid    = {32213642},
  url     = {https://doi.org/10.1212/wnl.0000000000009277}
}

@article{wessels2020-31764959,
  author  = {Wessels, A. M. and Tariot, P. N. and Zimmer, J. A. and Selzler, K. J. and Bragg, S. M. and Andersen, S. W. and Landry, J. and Krull, J. H. and others},
  title   = {{Efficacy and Safety of Lanabecestat for Treatment of Early and Mild Alzheimer Disease: The AMARANTH and DAYBREAK-ALZ Randomized Clinical Trials}},
  journal = {JAMA neurology},
  year    = {2020},
  doi     = {10.1001/jamaneurol.2019.3988},
  pmid    = {31764959},
  url     = {https://doi.org/10.1001/jamaneurol.2019.3988}
}

@article{howard2020-31738372,
  author  = {Howard, R. and Zubko, O. and Bradley, R. and Harper, E. and Pank, L. and O'Brien, J. and Fox, C. and Tabet, N. and others},
  title   = {{Minocycline at 2 Different Dosages vs Placebo for Patients With Mild Alzheimer Disease: A Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2020},
  doi     = {10.1001/jamaneurol.2019.3762},
  pmid    = {31738372},
  url     = {https://doi.org/10.1001/jamaneurol.2019.3762}
}

@article{sabbagh2020-31879235,
  author  = {Sabbagh, M. and Sadowsky, C. and Tousi, B. and Agronin, M. E. and Alva, G. and Armon, C. and Bernick, C. and Keegan, A. P. and others},
  title   = {{Effects of a combined transcranial magnetic stimulation (TMS) and cognitive training intervention in patients with Alzheimer's disease}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2020},
  doi     = {10.1016/j.jalz.2019.08.197},
  pmid    = {31879235},
  url     = {https://doi.org/10.1016/j.jalz.2019.08.197}
}

@article{gibson2020-33074237,
  author  = {Gibson, G. E. and Luchsinger, J. A. and Cirio, R. and Chen, H. and Franchino-Elder, J. and Hirsch, J. A. and Bettendorff, L. and Chen, Z. and others},
  title   = {{Benfotiamine and Cognitive Decline in Alzheimer's Disease: Results of a Randomized Placebo-Controlled Phase IIa Clinical Trial}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2020},
  doi     = {10.3233/jad-200896},
  pmid    = {33074237},
  url     = {https://doi.org/10.3233/jad-200896}
}

@article{wang2020-32920628,
  author  = {Wang, H. Y. and Pei, Z. and Lee, K. C. and Lopez-Brignoni, E. and Nikolov, B. and Crowley, C. A. and Marsman, M. R. and Barbier, R. and others},
  title   = {{PTI-125 Reduces Biomarkers of Alzheimer's Disease in Patients}},
  journal = {The journal of prevention of Alzheimer's disease},
  year    = {2020},
  doi     = {10.14283/jpad.2020.6},
  pmid    = {32920628},
  url     = {https://doi.org/10.14283/jpad.2020.6}
}

@article{portron2020-31883703,
  author  = {Portron, A. and Jordan, P. and Draper, K. and Muenzer, C. and Dickerson, D. and van Iersel, T. and Hofmann, C.},
  title   = {{A Phase I Study to Assess the Effect of Speed of Injection on Pain, Tolerability, and Pharmacokinetics After High-volume Subcutaneous Administration of Gantenerumab in Healthy Volunteers}},
  journal = {Clinical therapeutics},
  year    = {2020},
  doi     = {10.1016/j.clinthera.2019.11.015},
  pmid    = {31883703},
  url     = {https://doi.org/10.1016/j.clinthera.2019.11.015}
}

@article{jia2019-31801553,
  author  = {Jia, L. and Piña-Crespo, J. and Li, Y.},
  title   = {{Restoring Wnt/β-catenin signaling is a promising therapeutic strategy for Alzheimer's disease}},
  journal = {Molecular brain},
  year    = {2019},
  doi     = {10.1186/s13041-019-0525-5},
  pmid    = {31801553},
  url     = {https://doi.org/10.1186/s13041-019-0525-5}
}

@article{feustel2020-31792092,
  author  = {Feustel, A. C. and MacPherson, A. and Fergusson, D. A. and Kieburtz, K. and Kimmelman, J.},
  title   = {{Risks and benefits of unapproved disease-modifying treatments for neurodegenerative disease}},
  journal = {Neurology},
  year    = {2020},
  doi     = {10.1212/wnl.0000000000008699},
  pmid    = {31792092},
  url     = {https://doi.org/10.1212/wnl.0000000000008699}
}

@article{wang2019-31852125,
  author  = {Wang, H. and Liu, N. and Wei, Y. and Pei, H. and Liu, M. and Diao, X. and Zhang, H. and Li, H.},
  title   = {{Efficacy and safety of Shenmayizhi decoction as an adjuvant treatment for vascular dementia: Study protocol for a randomized controlled trial}},
  journal = {Medicine},
  year    = {2019},
  doi     = {10.1097/md.0000000000018326},
  pmid    = {31852125},
  url     = {https://doi.org/10.1097/md.0000000000018326}
}

@article{wang2020-31760522,
  author  = {Wang, X. and Mao, Z. and Ling, Z. and Yu, X.},
  title   = {{Repetitive transcranial magnetic stimulation for cognitive impairment in Alzheimer's disease: a meta-analysis of randomized controlled trials}},
  journal = {Journal of neurology},
  year    = {2020},
  doi     = {10.1007/s00415-019-09644-y},
  pmid    = {31760522},
  url     = {https://doi.org/10.1007/s00415-019-09644-y}
}

@article{schneider2019-31282954,
  author  = {Schneider, L. S. and Thomas, R. G. and Hendrix, S. and Rissman, R. A. and Brewer, J. B. and Salmon, D. P. and Oltersdorf, T. and Okuda, T. and others},
  title   = {{Safety and Efficacy of Edonerpic Maleate for Patients With Mild to Moderate Alzheimer Disease: A Phase 2 Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2019},
  doi     = {10.1001/jamaneurol.2019.1868},
  pmid    = {31282954},
  url     = {https://doi.org/10.1001/jamaneurol.2019.1868}
}

@article{li2020-31645180,
  author  = {Li, M. and Lyu, J. H. and Zhang, Y. and Gao, M. L. and Li, R. and Mao, P. X. and Li, W. J. and Ma, X. and others},
  title   = {{Efficacy of Group Reminiscence Therapy on Cognition, Depression, Neuropsychiatric Symptoms, and Activities of Daily Living for Patients With Alzheimer Disease}},
  journal = {Journal of geriatric psychiatry and neurology},
  year    = {2020},
  doi     = {10.1177/0891988719882099},
  pmid    = {31645180},
  url     = {https://doi.org/10.1177/0891988719882099}
}

@article{dyer2020-31604674,
  author  = {Dyer, A. H. and Murphy, C. and Lawlor, B. and Kennelly, S. P. and {NILVAD Study Group}},
  title   = {{Cognitive Outcomes of Long-term Benzodiazepine and Related Drug (BDZR) Use in People Living With Mild to Moderate Alzheimer's Disease: Results From NILVAD}},
  journal = {Journal of the American Medical Directors Association},
  year    = {2020},
  doi     = {10.1016/j.jamda.2019.08.006},
  pmid    = {31604674},
  url     = {https://doi.org/10.1016/j.jamda.2019.08.006}
}

@article{iranshahy2019-31998450,
  author  = {Iranshahy, M. and Javadi, B.},
  title   = {{Diet therapy for the treatment of Alzheimer's disease in view of traditional Persian medicine: A review}},
  journal = {Iranian journal of basic medical sciences},
  year    = {2019},
  doi     = {10.22038/ijbms.2019.36505.8694},
  pmid    = {31998450},
  url     = {https://doi.org/10.22038/ijbms.2019.36505.8694}
}

@article{vandyck2019-31329216,
  author  = {van Dyck, C. H. and Nygaard, H. B. and Chen, K. and Donohue, M. C. and Raman, R. and Rissman, R. A. and Brewer, J. B. and Koeppe, R. A. and others},
  title   = {{Effect of AZD0530 on Cerebral Metabolic Decline in Alzheimer Disease: A Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2019},
  doi     = {10.1001/jamaneurol.2019.2050},
  pmid    = {31329216},
  url     = {https://doi.org/10.1001/jamaneurol.2019.2050}
}

@article{roman2019-31521394,
  author  = {Román, G. C. and Jackson, R. E. and Reis, J. and Román, A. N. and Toledo, J. B. and Toledo, E.},
  title   = {{Extra-virgin olive oil for potential prevention of Alzheimer disease}},
  journal = {Revue neurologique},
  year    = {2019},
  doi     = {10.1016/j.neurol.2019.07.017},
  pmid    = {31521394},
  url     = {https://doi.org/10.1016/j.neurol.2019.07.017}
}

@article{schneider2019-31492718,
  author  = {Schneider, L. S. and Geffen, Y. and Rabinowitz, J. and Thomas, R. G. and Schmidt, R. and Ropele, S. and Weinstock, M. and {Ladostigil Study Group}},
  title   = {{Low-dose ladostigil for mild cognitive impairment: A phase 2 placebo-controlled clinical trial}},
  journal = {Neurology},
  year    = {2019},
  doi     = {10.1212/wnl.0000000000008239},
  pmid    = {31492718},
  url     = {https://doi.org/10.1212/wnl.0000000000008239}
}

@article{wang2019-31488882,
  author  = {Wang, X. and Sun, G. and Feng, T. and Zhang, J. and Huang, X. and Wang, T. and Xie, Z. and Chu, X. and others},
  title   = {{Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease progression}},
  journal = {Cell research},
  year    = {2019},
  doi     = {10.1038/s41422-019-0216-x},
  pmid    = {31488882},
  url     = {https://doi.org/10.1038/s41422-019-0216-x}
}

@article{rolland2019-31426362,
  author  = {Rolland, Y. and Barreto, P. S. and Maltais, M. and Guyonnet, S. and Cantet, C. and Andrieu, S. and Vellas, B.},
  title   = {{Effect of Long-Term Omega 3 Polyunsaturated Fatty Acid Supplementation with or without Multidomain Lifestyle Intervention on Muscle Strength in Older Adults: Secondary Analysis of the Multidomain Alzheimer Preventive Trial (MAPT)}},
  journal = {Nutrients},
  year    = {2019},
  doi     = {10.3390/nu11081931},
  pmid    = {31426362},
  url     = {https://doi.org/10.3390/nu11081931}
}

@article{paula2019-31226738,
  author  = {Paula, P. C. and Angelica Maria, S. G. and Luis, C. H. and Gloria Patricia, C. G.},
  title   = {{Preventive Effect of Quercetin in a Triple Transgenic Alzheimer's Disease Mice Model}},
  journal = {Molecules (Basel, Switzerland)},
  year    = {2019},
  doi     = {10.3390/molecules24122287},
  pmid    = {31226738},
  url     = {https://doi.org/10.3390/molecules24122287}
}

@article{dejong2019-31203725,
  author  = {de Jong, D. L. K. and de Heus, R. A. A. and Rijpma, A. and Donders, R. and Olde Rikkert, M. G. M. and Günther, M. and Lawlor, B. A. and van Osch, M. J. P. and others},
  title   = {{Effects of Nilvadipine on Cerebral Blood Flow in Patients With Alzheimer Disease}},
  journal = {Hypertension (Dallas, Tex. : 1979)},
  year    = {2019},
  doi     = {10.1161/hypertensionaha.119.12892},
  pmid    = {31203725},
  url     = {https://doi.org/10.1161/hypertensionaha.119.12892}
}

@article{elbakly2019-31163203,
  author  = {El-Bakly, W. and Wagdy, O. and Sobhy, A. and Abo Elenain, O. and Riad, M. S. and El Sayed, M. and Tarkhan, S. and Yassen, M. and others},
  title   = {{The efficacy and underlying mechanism of phosphodiesterase- 5 inhibitors in preventing cognitive impairment and Alzheimer pathology: A systematic review of animal studies}},
  journal = {Behavioural brain research},
  year    = {2019},
  doi     = {10.1016/j.bbr.2019.112004},
  pmid    = {31163203},
  url     = {https://doi.org/10.1016/j.bbr.2019.112004}
}

@article{deheus2019-31088188,
  author  = {de Heus, R. A. A. and Donders, R. and Santoso, A. M. M. and Olde Rikkert, M. G. M. and Lawlor, B. A. and Claassen, J. A. H. R. and {Nilvad Study Group}},
  title   = {{Blood Pressure Lowering With Nilvadipine in Patients With Mild-to-Moderate Alzheimer Disease Does Not Increase the Prevalence of Orthostatic Hypotension}},
  journal = {Journal of the American Heart Association},
  year    = {2019},
  doi     = {10.1161/jaha.119.011938},
  pmid    = {31088188},
  url     = {https://doi.org/10.1161/jaha.119.011938}
}

@article{zuidersma2019-31084994,
  author  = {Zuidersma, M. and Chua, K. C. and Hellier, J. and Voshaar, R. O. and Banerjee, S. and {HTA-SADD Investigator Group}},
  title   = {{Sertraline and Mirtazapine Versus Placebo in Subgroups of Depression in Dementia: Findings From the HTA-SADD Randomized Controlled Trial}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2019},
  doi     = {10.1016/j.jagp.2019.03.021},
  pmid    = {31084994},
  url     = {https://doi.org/10.1016/j.jagp.2019.03.021}
}

@article{meyer2019-30952794,
  author  = {Meyer, P. F. and Tremblay-Mercier, J. and Leoutsakos, J. and Madjar, C. and Lafaille-Magnan, M. E. and Savard, M. and Rosa-Neto, P. and Poirier, J. and others},
  title   = {{INTREPAD: A randomized trial of naproxen to slow progress of presymptomatic Alzheimer disease}},
  journal = {Neurology},
  year    = {2019},
  doi     = {10.1212/wnl.0000000000007232},
  pmid    = {30952794},
  url     = {https://doi.org/10.1212/wnl.0000000000007232}
}

@article{han2019-30633043,
  author  = {Han, J. Y. and Besser, L. M. and Xiong, C. and Kukull, W. A. and Morris, J. C.},
  title   = {{Cholinesterase Inhibitors May Not Benefit Mild Cognitive Impairment and Mild Alzheimer Disease Dementia}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2019},
  doi     = {10.1097/wad.0000000000000291},
  pmid    = {30633043},
  url     = {https://doi.org/10.1097/wad.0000000000000291}
}

@article{egan2019-30970186,
  author  = {Egan, M. F. and Kost, J. and Voss, T. and Mukai, Y. and Aisen, P. S. and Cummings, J. L. and Tariot, P. N. and Vellas, B. and others},
  title   = {{Randomized Trial of Verubecestat for Prodromal Alzheimer's Disease}},
  journal = {The New England journal of medicine},
  year    = {2019},
  doi     = {10.1056/nejmoa1812840},
  pmid    = {30970186},
  url     = {https://doi.org/10.1056/nejmoa1812840}
}

@article{mcshane2019-30891742,
  author  = {McShane, R. and Westby, M. J. and Roberts, E. and Minakaran, N. and Schneider, L. and Farrimond, L. E. and Maayan, N. and Ware, J. and others},
  title   = {{Memantine for dementia}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2019},
  doi     = {10.1002/14651858.cd003154.pub6},
  pmid    = {30891742},
  url     = {https://doi.org/10.1002/14651858.cd003154.pub6}
}

@article{dinda2019-30877973,
  author  = {Dinda, B. and Dinda, M. and Kulsi, G. and Chakraborty, A. and Dinda, S.},
  title   = {{Therapeutic potentials of plant iridoids in Alzheimer's and Parkinson's diseases: A review}},
  journal = {European journal of medicinal chemistry},
  year    = {2019},
  doi     = {10.1016/j.ejmech.2019.03.009},
  pmid    = {30877973},
  url     = {https://doi.org/10.1016/j.ejmech.2019.03.009}
}

@article{yunusa2019-30901041,
  author  = {Yunusa, I. and Alsumali, A. and Garba, A. E. and Regestein, Q. R. and Eguale, T.},
  title   = {{Assessment of Reported Comparative Effectiveness and Safety of Atypical Antipsychotics in the Treatment of Behavioral and Psychological Symptoms of Dementia: A Network Meta-analysis}},
  journal = {JAMA network open},
  year    = {2019},
  doi     = {10.1001/jamanetworkopen.2019.0828},
  pmid    = {30901041},
  url     = {https://doi.org/10.1001/jamanetworkopen.2019.0828}
}

@article{maltais2019-30817982,
  author  = {Maltais, M. and de Souto Barreto, P. and Pothier, K. and Cantet, C. and Andrieu, S. and Rolland, Y. and Vellas, B. and {MAPT/DSA Study Group}},
  title   = {{Lifestyle multidomain intervention, omega-3 supplementation, or both for reducing the risk of developing clinically relevant depressive symptoms in older adults with memory complaints? Secondary analysis from the MAPT trial}},
  journal = {Experimental gerontology},
  year    = {2019},
  doi     = {10.1016/j.exger.2019.02.010},
  pmid    = {30817982},
  url     = {https://doi.org/10.1016/j.exger.2019.02.010}
}

@article{silveira2019-30738426,
  author  = {Silveira, C. R. A. and MacKinley, J. and Coleman, K. and Li, Z. and Finger, E. and Bartha, R. and Morrow, S. A. and Wells, J. and others},
  title   = {{Ambroxol as a novel disease-modifying treatment for Parkinson's disease dementia: protocol for a single-centre, randomized, double-blind, placebo-controlled trial}},
  journal = {BMC neurology},
  year    = {2019},
  doi     = {10.1186/s12883-019-1252-3},
  pmid    = {30738426},
  url     = {https://doi.org/10.1186/s12883-019-1252-3}
}

@article{sha2019-30383097,
  author  = {Sha, S. J. and Deutsch, G. K. and Tian, L. and Richardson, K. and Coburn, M. and Gaudioso, J. L. and Marcal, T. and Solomon, E. and others},
  title   = {{Safety, Tolerability, and Feasibility of Young Plasma Infusion in the Plasma for Alzheimer Symptom Amelioration Study: A Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2019},
  doi     = {10.1001/jamaneurol.2018.3288},
  pmid    = {30383097},
  url     = {https://doi.org/10.1001/jamaneurol.2018.3288}
}

@article{uto2018-30619872,
  author  = {Uto, N. S. and Amitani, H. and Atobe, Y. and Sameshima, Y. and Sakaki, M. and Rokot, N. and Ataka, K. and Amitani, M. and others},
  title   = {{Herbal Medicine Ninjin'yoeito in the Treatment of Sarcopenia and Frailty}},
  journal = {Frontiers in nutrition},
  year    = {2018},
  doi     = {10.3389/fnut.2018.00126},
  pmid    = {30619872},
  url     = {https://doi.org/10.3389/fnut.2018.00126}
}

@article{scholz2018-30333067,
  author  = {Scholz, R. and Lemcke, J. and Meier, U. and Stengel, D.},
  title   = {{Efficacy and safety of programmable compared with fixed anti-siphon devices for treating idiopathic normal-pressure hydrocephalus (iNPH) in adults - SYGRAVA: study protocol for a randomized trial}},
  journal = {Trials},
  year    = {2018},
  doi     = {10.1186/s13063-018-2951-6},
  pmid    = {30333067},
  url     = {https://doi.org/10.1186/s13063-018-2951-6}
}

@article{scheltens2018-30309389,
  author  = {Scheltens, P. and Hallikainen, M. and Grimmer, T. and Duning, T. and Gouw, A. A. and Teunissen, C. E. and Wink, A. M. and Maruff, P. and others},
  title   = {{Safety, tolerability and efficacy of the glutaminyl cyclase inhibitor PQ912 in Alzheimer's disease: results of a randomized, double-blind, placebo-controlled phase 2a study}},
  journal = {Alzheimer's research \& therapy},
  year    = {2018},
  doi     = {10.1186/s13195-018-0431-6},
  pmid    = {30309389},
  url     = {https://doi.org/10.1186/s13195-018-0431-6}
}

@article{lawlor2018-30248105,
  author  = {Lawlor, B. and Segurado, R. and Kennelly, S. and Olde Rikkert, M. G. M. and Howard, R. and Pasquier, F. and Börjesson-Hanson, A. and Tsolaki, M. and others},
  title   = {{Nilvadipine in mild to moderate Alzheimer disease: A randomised controlled trial}},
  journal = {PLoS medicine},
  year    = {2018},
  doi     = {10.1371/journal.pmed.1002660},
  pmid    = {30248105},
  url     = {https://doi.org/10.1371/journal.pmed.1002660}
}

@article{lok2019-30246408,
  author  = {Lök, N. and Bademli, K. and Selçuk-Tosun, A.},
  title   = {{The effect of reminiscence therapy on cognitive functions, depression, and quality of life in Alzheimer patients: Randomized controlled trial}},
  journal = {International journal of geriatric psychiatry},
  year    = {2019},
  doi     = {10.1002/gps.4980},
  pmid    = {30246408},
  url     = {https://doi.org/10.1002/gps.4980}
}

@article{marron2018-30185210,
  author  = {Marron, E. M. and Viejo-Sobera, R. and Quintana, M. and Redolar-Ripoll, D. and Rodríguez, D. and Garolera, M.},
  title   = {{Transcranial magnetic stimulation intervention in Alzheimer's disease: a research proposal for a randomized controlled trial}},
  journal = {BMC research notes},
  year    = {2018},
  doi     = {10.1186/s13104-018-3757-z},
  pmid    = {30185210},
  url     = {https://doi.org/10.1186/s13104-018-3757-z}
}

@article{birks2018-29923184,
  author  = {Birks, J. S. and Harvey, R. J.},
  title   = {{Donepezil for dementia due to Alzheimer's disease}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2018},
  doi     = {10.1002/14651858.cd001190.pub3},
  pmid    = {29923184},
  url     = {https://doi.org/10.1002/14651858.cd001190.pub3}
}

@article{chhugani2018-31370033,
  author  = {Chhugani, K. J. and Metri, K. and Babu, N. and Nagendra, H. R.},
  title   = {{Effects of Integrated Yoga Intervention on Psychopathologies and Sleep Quality Among Professional Caregivers of Older Adults With Alzheimer's Disease: A Controlled Pilot Study}},
  journal = {Advances in mind-body medicine},
  year    = {2018},
  pmid    = {31370033}
}

@article{lamb2018-29769247,
  author  = {Lamb, S. E. and Sheehan, B. and Atherton, N. and Nichols, V. and Collins, H. and Mistry, D. and others},
  title   = {{Dementia And Physical Activity (DAPA) trial of moderate to high intensity exercise training for people with dementia: randomised controlled trial}},
  journal = {BMJ},
  year    = {2018},
  doi     = {10.1136/bmj.k1675},
  pmid    = {29769247},
  url     = {https://doi.org/10.1136/bmj.k1675}
}

@article{knight2018-29734182,
  author  = {Knight, R. and Khondoker, M. and Magill, N. and Stewart, R. and Landau, S.},
  title   = {{A Systematic Review and Meta-Analysis of the Effectiveness of Acetylcholinesterase Inhibitors and Memantine in Treating the Cognitive Symptoms of Dementia}},
  journal = {Dementia and geriatric cognitive disorders},
  year    = {2018},
  doi     = {10.1159/000486546},
  pmid    = {29734182},
  url     = {https://doi.org/10.1159/000486546}
}

@article{egan2018-29719179,
  author  = {Egan, M. F. and Kost, J. and Tariot, P. N. and Aisen, P. S. and Cummings, J. L. and Vellas, B. and Sur, C. and Mukai, Y. and others},
  title   = {{Randomized Trial of Verubecestat for Mild-to-Moderate Alzheimer's Disease}},
  journal = {The New England journal of medicine},
  year    = {2018},
  doi     = {10.1056/nejmoa1706441},
  pmid    = {29719179},
  url     = {https://doi.org/10.1056/nejmoa1706441}
}

@article{cummings2018-29695589,
  author  = {Cummings, J. L. and Cohen, S. and van Dyck, C. H. and Brody, M. and Curtis, C. and Cho, W. and Ward, M. and Friesenhahn, M. and others},
  title   = {{ABBY: A phase 2 randomized trial of crenezumab in mild to moderate Alzheimer disease}},
  journal = {Neurology},
  year    = {2018},
  doi     = {10.1212/wnl.0000000000005550},
  pmid    = {29695589},
  url     = {https://doi.org/10.1212/wnl.0000000000005550}
}

@article{monteroodasso2018-29661156,
  author  = {Montero-Odasso, M. and Almeida, Q. J. and Burhan, A. M. and Camicioli, R. and Doyon, J. and Fraser, S. and Li, K. and Liu-Ambrose, T. and others},
  title   = {{SYNERGIC TRIAL (SYNchronizing Exercises, Remedies in Gait and Cognition) a multi-Centre randomized controlled double blind trial to improve gait and cognition in mild cognitive impairment}},
  journal = {BMC geriatrics},
  year    = {2018},
  doi     = {10.1186/s12877-018-0782-7},
  pmid    = {29661156},
  url     = {https://doi.org/10.1186/s12877-018-0782-7}
}

@article{tzeng2018-29488144,
  author  = {Tzeng, N. S. and Chung, C. H. and Lin, F. H. and Chiang, C. P. and Yeh, C. B. and Huang, S. Y. and Lu, R. B. and Chang, H. A. and others},
  title   = {{Anti-herpetic Medications and Reduced Risk of Dementia in Patients with Herpes Simplex Virus Infections-a Nationwide, Population-Based Cohort Study in Taiwan}},
  journal = {Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics},
  year    = {2018},
  doi     = {10.1007/s13311-018-0611-x},
  pmid    = {29488144},
  url     = {https://doi.org/10.1007/s13311-018-0611-x}
}

@article{tariot2018-29955659,
  author  = {Tariot, P. N. and Lopera, F. and Langbaum, J. B. and Thomas, R. G. and Hendrix, S. and Schneider, L. S. and Rios-Romenets, S. and Giraldo, M. and others},
  title   = {{The Alzheimer's Prevention Initiative Autosomal-Dominant Alzheimer's Disease Trial: A study of crenezumab versus placebo in preclinical PSEN1 E280A mutation carriers to evaluate efficacy and safety in the treatment of autosomal-dominant Alzheimer's disease, including a placebo-treated noncarrier cohort}},
  journal = {Alzheimer's \& dementia (New York, N. Y.)},
  year    = {2018},
  doi     = {10.1016/j.trci.2018.02.002},
  pmid    = {29955659},
  url     = {https://doi.org/10.1016/j.trci.2018.02.002}
}

@article{qaseem2018-29507945,
  author  = {Qaseem, A. and Wilt, T. J. and Kansagara, D. and Horwitch, C. and Barry, M. J. and Forciea, M. A. and {Clinical Guidelines Committee of the American College of Physicians} and Fitterman, N. and others},
  title   = {{Hemoglobin A1c Targets for Glycemic Control With Pharmacologic Therapy for Nonpregnant Adults With Type 2 Diabetes Mellitus: A Guidance Statement Update From the American College of Physicians}},
  journal = {Annals of internal medicine},
  year    = {2018},
  doi     = {10.7326/m17-0939},
  pmid    = {29507945},
  url     = {https://doi.org/10.7326/m17-0939}
}

@article{liu2018-29429971,
  author  = {Liu, E. and Wang, D. and Sperling, R. and Salloway, S. and Fox, N. C. and Blennow, K. and Scheltens, P. and Schmidt, M. E. and others},
  title   = {{Biomarker pattern of ARIA-E participants in phase 3 randomized clinical trials with bapineuzumab}},
  journal = {Neurology},
  year    = {2018},
  doi     = {10.1212/wnl.0000000000005060},
  pmid    = {29429971},
  url     = {https://doi.org/10.1212/wnl.0000000000005060}
}

@article{reinhardt2018-29358714,
  author  = {Reinhardt, S. and Stoye, N. and Luderer, M. and Kiefer, F. and Schmitt, U. and Lieb, K. and Endres, K.},
  title   = {{Identification of disulfiram as a secretase-modulating compound with beneficial effects on Alzheimer's disease hallmarks}},
  journal = {Scientific reports},
  year    = {2018},
  doi     = {10.1038/s41598-018-19577-7},
  pmid    = {29358714},
  url     = {https://doi.org/10.1038/s41598-018-19577-7}
}

@article{mervin2018-29325922,
  author  = {Mervin, M. C. and Moyle, W. and Jones, C. and Murfield, J. and Draper, B. and Beattie, E. and Shum, D. H. K. and O'Dwyer, S. and others},
  title   = {{The Cost-Effectiveness of Using PARO, a Therapeutic Robotic Seal, to Reduce Agitation and Medication Use in Dementia: Findings from a Cluster-Randomized Controlled Trial}},
  journal = {Journal of the American Medical Directors Association},
  year    = {2018},
  doi     = {10.1016/j.jamda.2017.10.008},
  pmid    = {29325922},
  url     = {https://doi.org/10.1016/j.jamda.2017.10.008}
}

@article{leoutsakos2018-29914028,
  author  = {Leoutsakos, J. S. and Yan, H. and Anderson, W. S. and Asaad, W. F. and Baltuch, G. and Burke, A. and Chakravarty, M. M. and Drake, K. E. and others},
  title   = {{Deep Brain Stimulation Targeting the Fornix for Mild Alzheimer Dementia (the ADvance Trial): A Two Year Follow-up Including Results of Delayed Activation}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2018},
  doi     = {10.3233/jad-180121},
  pmid    = {29914028},
  url     = {https://doi.org/10.3233/jad-180121}
}

@article{atri2018-29318278,
  author  = {Atri, A. and Frölich, L. and Ballard, C. and Tariot, P. N. and Molinuevo, J. L. and Boneva, N. and Windfeld, K. and Raket, L. L. and others},
  title   = {{Effect of Idalopirdine as Adjunct to Cholinesterase Inhibitors on Change in Cognition in Patients With Alzheimer Disease: Three Randomized Clinical Trials}},
  journal = {JAMA},
  year    = {2018},
  doi     = {10.1001/jama.2017.20373},
  pmid    = {29318278},
  url     = {https://doi.org/10.1001/jama.2017.20373}
}

@article{nguyen2018-29658441,
  author  = {Nguyen, J. P. and Boutoleau-Bretonniere, C. and Lefaucheur, J. P. and Suarez, A. and Gaillard, H. and Chapelet, G. and Abad, S. and Van Langhenhove, A. and others},
  title   = {{Efficacy of Transcranial Direct Current Stimulation Combined with Cognitive Training in the Treatment of Apathy in Patients with Alzheimer's Disease: Study Protocol for a Randomized Trial}},
  journal = {Reviews on recent clinical trials},
  year    = {2018},
  doi     = {10.2174/1574887113666180416153316},
  pmid    = {29658441},
  url     = {https://doi.org/10.2174/1574887113666180416153316}
}

@article{pang2018-29425590,
  author  = {Pang, X. C. and Kang and Fang, J. S. and Zhao, Y. and Xu, L. J. and Lian, W. W. and Liu, A. L. and DU, G. H.},
  title   = {{Network pharmacology-based analysis of Chinese herbal Naodesheng formula for application to Alzheimer's disease}},
  journal = {Chinese journal of natural medicines},
  year    = {2018},
  doi     = {10.1016/s1875-5364(18)30029-3},
  pmid    = {29425590},
  url     = {https://doi.org/10.1016/s1875-5364(18)30029-3}
}

@article{leblhuber2018-30101706,
  author  = {Leblhuber, F. and Steiner, K. and Schuetz, B. and Fuchs, D. and Gostner, J. M.},
  title   = {{Probiotic Supplementation in Patients with Alzheimer's Dementia - An Explorative Intervention Study}},
  journal = {Current Alzheimer research},
  year    = {2018},
  doi     = {10.2174/1389200219666180813144834},
  pmid    = {30101706},
  url     = {https://doi.org/10.2174/1389200219666180813144834}
}

@article{chhetri2018-29405230,
  author  = {Chhetri, J. K. and de Souto Barreto, P. and Cantet, C. and Cesari, M. and Coley, N. and Andrieu, S. and Vellas, B.},
  title   = {{Trajectory of the MAPT-PACC-Preclinical Alzheimer Cognitive Composite in the Placebo Group of a Randomized Control Trial: Results from the MAPT Study: Lessons for Further Trials}},
  journal = {The journal of prevention of Alzheimer's disease},
  year    = {2018},
  doi     = {10.14283/jpad.2017.21},
  pmid    = {29405230},
  url     = {https://doi.org/10.14283/jpad.2017.21}
}

@article{honig2018-29365294,
  author  = {Honig, L. S. and Vellas, B. and Woodward, M. and Boada, M. and Bullock, R. and Borrie, M. and Hager, K. and Andreasen, N. and others},
  title   = {{Trial of Solanezumab for Mild Dementia Due to Alzheimer's Disease}},
  journal = {The New England journal of medicine},
  year    = {2018},
  doi     = {10.1056/nejmoa1705971},
  pmid    = {29365294},
  url     = {https://doi.org/10.1056/nejmoa1705971}
}

@article{jia2017-29284465,
  author  = {Jia, Y. and Zhang, X. and Yu, J. and Han, J. and Yu, T. and Shi, J. and Zhao, L. and Nie, K.},
  title   = {{Acupuncture for patients with mild to moderate Alzheimer's disease: a randomized controlled trial}},
  journal = {BMC complementary and alternative medicine},
  year    = {2017},
  doi     = {10.1186/s12906-017-2064-x},
  pmid    = {29284465},
  url     = {https://doi.org/10.1186/s12906-017-2064-x}
}

@article{ostrowitzki2017-29221491,
  author  = {Ostrowitzki, S. and Lasser, R. A. and Dorflinger, E. and Scheltens, P. and Barkhof, F. and Nikolcheva, T. and Ashford, E. and Retout, S. and others},
  title   = {{A phase III randomized trial of gantenerumab in prodromal Alzheimer's disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2017},
  doi     = {10.1186/s13195-017-0318-y},
  pmid    = {29221491},
  url     = {https://doi.org/10.1186/s13195-017-0318-y}
}

@article{li2017-29390538,
  author  = {Li, M. and Lyu, J. H. and Zhang, Y. and Gao, M. L. and Li, W. J. and Ma, X.},
  title   = {{The clinical efficacy of reminiscence therapy in patients with mild-to-moderate Alzheimer disease: Study protocol for a randomized parallel-design controlled trial}},
  journal = {Medicine},
  year    = {2017},
  doi     = {10.1097/md.0000000000009381},
  pmid    = {29390538},
  url     = {https://doi.org/10.1097/md.0000000000009381}
}

@article{seo2018-29179999,
  author  = {Seo, E. J. and Fischer, N. and Efferth, T.},
  title   = {{Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer's disease}},
  journal = {Pharmacological research},
  year    = {2018},
  doi     = {10.1016/j.phrs.2017.11.030},
  pmid    = {29179999},
  url     = {https://doi.org/10.1016/j.phrs.2017.11.030}
}

@article{li2017-28821686,
  author  = {Li, G. and Mayer, C. L. and Morelli, D. and Millard, S. P. and Raskind, W. H. and Petrie, E. C. and Cherrier, M. and Fagan, A. M. and others},
  title   = {{Effect of simvastatin on CSF Alzheimer disease biomarkers in cognitively normal adults}},
  journal = {Neurology},
  year    = {2017},
  doi     = {10.1212/wnl.0000000000004392},
  pmid    = {28821686},
  url     = {https://doi.org/10.1212/wnl.0000000000004392}
}

@article{tian2017-28596794,
  author  = {Tian, J. and Shi, J. and Li, T. and Li, L. and Wang, Z. and Li, X. and Lv, Z. and Zheng, Q. and others},
  title   = {{Efficacy and Safety of an Herbal Therapy in Patients with Amnestic Mild Cognitive Impairment: A 24-Week Randomized Phase III Trial}},
  journal = {Evidence-based complementary and alternative medicine : eCAM},
  year    = {2017},
  doi     = {10.1155/2017/4251747},
  pmid    = {28596794},
  url     = {https://doi.org/10.1155/2017/4251747}
}

@article{cheng2017-28356312,
  author  = {Cheng, Y. S. and Chen, Z. T. and Liao, T. Y. and Lin, C. and Shen, H. C. and Wang, Y. H. and Chang, C. W. and Liu, R. S. and others},
  title   = {{An intranasally delivered peptide drug ameliorates cognitive decline in Alzheimer transgenic mice}},
  journal = {EMBO molecular medicine},
  year    = {2017},
  doi     = {10.15252/emmm.201606666},
  pmid    = {28356312},
  url     = {https://doi.org/10.15252/emmm.201606666}
}

@article{kryscio2017-28319243,
  author  = {Kryscio, R. J. and Abner, E. L. and Caban-Holt, A. and Lovell, M. and Goodman, P. and Darke, A. K. and Yee, M. and Crowley, J. and others},
  title   = {{Association of Antioxidant Supplement Use and Dementia in the Prevention of Alzheimer's Disease by Vitamin E and Selenium Trial (PREADViSE)}},
  journal = {JAMA neurology},
  year    = {2017},
  doi     = {10.1001/jamaneurol.2016.5778},
  pmid    = {28319243},
  url     = {https://doi.org/10.1001/jamaneurol.2016.5778}
}

@article{wang2017-29067332,
  author  = {Wang, C. Y. and Wang, P. N. and Chiu, M. J. and Finstad, C. L. and Lin, F. and Lynn, S. and Tai, Y. H. and De Fang, X. and others},
  title   = {{UB-311, a novel UBITh® amyloid β peptide vaccine for mild Alzheimer's disease}},
  journal = {Alzheimer's \& dementia (New York, N. Y.)},
  year    = {2017},
  doi     = {10.1016/j.trci.2017.03.005},
  pmid    = {29067332},
  url     = {https://doi.org/10.1016/j.trci.2017.03.005}
}

@article{koenig2017-28538088,
  author  = {Koenig, A. M. and Mechanic-Hamilton, D. and Xie, S. X. and Combs, M. F. and Cappola, A. R. and Xie, L. and Detre, J. A. and Wolk, D. A. and others},
  title   = {{Effects of the Insulin Sensitizer Metformin in Alzheimer Disease: Pilot Data From a Randomized Placebo-controlled Crossover Study}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2017},
  doi     = {10.1097/wad.0000000000000202},
  pmid    = {28538088},
  url     = {https://doi.org/10.1097/wad.0000000000000202}
}

@article{yao2017-28330719,
  author  = {Yao, Z. and Yang, W. and Gao, Z. and Jia, P.},
  title   = {{Nicotinamide mononucleotide inhibits JNK activation to reverse Alzheimer disease}},
  journal = {Neuroscience letters},
  year    = {2017},
  doi     = {10.1016/j.neulet.2017.03.027},
  pmid    = {28330719},
  url     = {https://doi.org/10.1016/j.neulet.2017.03.027}
}

@article{boespflug2018-28221821,
  author  = {Boespflug, E. L. and Eliassen, J. C. and Dudley, J. A. and Shidler, M. D. and Kalt, W. and Summer, S. S. and Stein, A. L. and Stover, A. N. and others},
  title   = {{Enhanced neural activation with blueberry supplementation in mild cognitive impairment}},
  journal = {Nutritional neuroscience},
  year    = {2018},
  doi     = {10.1080/1028415x.2017.1287833},
  pmid    = {28221821},
  url     = {https://doi.org/10.1080/1028415x.2017.1287833}
}

@article{morris2017-28187125,
  author  = {Morris, J. K. and Vidoni, E. D. and Johnson, D. K. and Van Sciver, A. and Mahnken, J. D. and Honea, R. A. and Wilkins, H. M. and Brooks, W. M. and others},
  title   = {{Aerobic exercise for Alzheimer's disease: A randomized controlled pilot trial}},
  journal = {PloS one},
  year    = {2017},
  doi     = {10.1371/journal.pone.0170547},
  pmid    = {28187125},
  url     = {https://doi.org/10.1371/journal.pone.0170547}
}

@article{saltmarche2017-28186867,
  author  = {Saltmarche, A. E. and Naeser, M. A. and Ho, K. F. and Hamblin, M. R. and Lim, L.},
  title   = {{Significant Improvement in Cognition in Mild to Moderately Severe Dementia Cases Treated with Transcranial Plus Intranasal Photobiomodulation: Case Series Report}},
  journal = {Photomedicine and laser surgery},
  year    = {2017},
  doi     = {10.1089/pho.2016.4227},
  pmid    = {28186867},
  url     = {https://doi.org/10.1089/pho.2016.4227}
}

@article{marjoribanks2017-28093732,
  author  = {Marjoribanks, J. and Farquhar, C. and Roberts, H. and Lethaby, A. and Lee, J.},
  title   = {{Long-term hormone therapy for perimenopausal and postmenopausal women}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2017},
  doi     = {10.1002/14651858.cd004143.pub5},
  pmid    = {28093732},
  url     = {https://doi.org/10.1002/14651858.cd004143.pub5}
}

@article{bloniecki2017-28269767,
  author  = {Bloniecki, V. and Aarsland, D. and Blennow, K. and Cummings, J. and Falahati, F. and Winblad, B. and Freund-Levi, Y.},
  title   = {{Effects of Risperidone and Galantamine Treatment on Alzheimer's Disease Biomarker Levels in Cerebrospinal Fluid}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2017},
  doi     = {10.3233/jad-160758},
  pmid    = {28269767},
  url     = {https://doi.org/10.3233/jad-160758}
}

@article{baek2016-28119873,
  author  = {Baek, S. S. and Kim, S. H.},
  title   = {{Treadmill exercise ameliorates symptoms of Alzheimer disease through suppressing microglial activation-induced apoptosis in rats}},
  journal = {Journal of exercise rehabilitation},
  year    = {2016},
  doi     = {10.12965/jer.1632858.429},
  pmid    = {28119873},
  url     = {https://doi.org/10.12965/jer.1632858.429}
}

@article{regan2017-28034509,
  author  = {Regan, B. and Wells, Y. and Farrow, M. and O'Halloran, P. and Workman, B.},
  title   = {{MAXCOG-Maximizing Cognition: A Randomized Controlled Trial of the Efficacy of Goal-Oriented Cognitive Rehabilitation for People with Mild Cognitive Impairment and Early Alzheimer Disease}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2017},
  doi     = {10.1016/j.jagp.2016.11.008},
  pmid    = {28034509},
  url     = {https://doi.org/10.1016/j.jagp.2016.11.008}
}

@article{brody2016-27589523,
  author  = {Brody, M. and Liu, E. and Di, J. and Lu, M. and Margolin, R. A. and Werth, J. L. and Booth, K. and Shadman, A. and others},
  title   = {{A Phase II, Randomized, Double-Blind, Placebo-Controlled Study of Safety, Pharmacokinetics, and Biomarker Results of Subcutaneous Bapineuzumab in Patients with mild to moderate Alzheimer's disease}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2016},
  doi     = {10.3233/jad-160369},
  pmid    = {27589523},
  url     = {https://doi.org/10.3233/jad-160369}
}

@article{rabey2016-27631152,
  author  = {Rabey, J. M. and Dobronevsky, E.},
  title   = {{Repetitive transcranial magnetic stimulation (rTMS) combined with cognitive training is a safe and effective modality for the treatment of Alzheimer's disease: clinical experience}},
  journal = {Journal of neural transmission (Vienna, Austria : 1996)},
  year    = {2016},
  doi     = {10.1007/s00702-016-1606-6},
  pmid    = {27631152},
  url     = {https://doi.org/10.1007/s00702-016-1606-6}
}

@article{lozano2016-27567810,
  author  = {Lozano, A. M. and Fosdick, L. and Chakravarty, M. M. and Leoutsakos, J. M. and Munro, C. and Oh, E. and Drake, K. E. and Lyman, C. H. and others},
  title   = {{A Phase II Study of Fornix Deep Brain Stimulation in Mild Alzheimer's Disease}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2016},
  doi     = {10.3233/jad-160017},
  pmid    = {27567810},
  url     = {https://doi.org/10.3233/jad-160017}
}

@article{sevigny2016-27582220,
  author  = {Sevigny, Jeff and Chiao, Ping and Bussière, Thierry and Weinreb, Paul H. and Williams, Leslie J. and Maier, Marcel and Dunstan, Robert W. and Salloway, Stephen and others},
  title   = {{The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease}},
  journal = {Nature},
  year    = {2016},
  doi     = {10.1038/nature19323},
  pmid    = {27582220},
  url     = {https://doi.org/10.1038/nature19323}
}

@article{skvarc2016-27502769,
  author  = {Skvarc, D. R. and Dean, O. M. and Byrne, L. K. and Gray, L. J. and Ives, K. and Lane, S. E. and Lewis, M. and Osborne, C. and others},
  title   = {{The Post-Anaesthesia N-acetylcysteine Cognitive Evaluation (PANACEA) trial: study protocol for a randomised controlled trial}},
  journal = {Trials},
  year    = {2016},
  doi     = {10.1186/s13063-016-1529-4},
  pmid    = {27502769},
  url     = {https://doi.org/10.1186/s13063-016-1529-4}
}

@article{hartin2016-27485822,
  author  = {Hartin, P. J. and Nugent, C. D. and McClean, S. I. and Cleland, I. and Tschanz, J. T. and Clark, C. J. and Norton, M. C.},
  title   = {{The Empowering Role of Mobile Apps in Behavior Change Interventions: The Gray Matters Randomized Controlled Trial}},
  journal = {JMIR mHealth and uHealth},
  year    = {2016},
  doi     = {10.2196/mhealth.4878},
  pmid    = {27485822},
  url     = {https://doi.org/10.2196/mhealth.4878}
}

@article{wielage2016-27326725,
  author  = {Wielage, Ronald C. and Perk, Sinem and Campbell, Noll L. and Klein, Timothy M. and Posta, Linda M. and Yuran, Thomas E. and Klein, Robert W. and Ng, Daniel},
  title   = {{Mirabegron for the treatment of overactive bladder: cost-effectiveness from US commercial health-plan and Medicare Advantage perspectives}},
  journal = {Journal of Medical Economics},
  year    = {2016},
  doi     = {10.1080/13696998.2016.1204307},
  pmid    = {27326725},
  url     = {https://doi.org/10.1080/13696998.2016.1204307}
}

@article{jacobs2016-27236255,
  author  = {Jacobs, V. and May, H. T. and Bair, T. L. and Crandall, B. G. and Cutler, M. J. and Day, J. D. and Mallender, C. and Osborn, J. S. and others},
  title   = {{Long-Term Population-Based Cerebral Ischemic Event and Cognitive Outcomes of Direct Oral Anticoagulants Compared With Warfarin Among Long-term Anticoagulated Patients for Atrial Fibrillation}},
  journal = {The American journal of cardiology},
  year    = {2016},
  doi     = {10.1016/j.amjcard.2016.04.039},
  pmid    = {27236255},
  url     = {https://doi.org/10.1016/j.amjcard.2016.04.039}
}

@article{andrade2016-29213448,
  author  = {Andrade, S. M. and de Mendonça, C. T. P. L. and Pereira, T. C. L. and Fernandez-Calvo, B. and Araújo, R. C. N. and Alves, N. T.},
  title   = {{Adjuvant transcranial direct current stimulation for treating Alzheimer's disease: A case study}},
  journal = {Dementia \& neuropsychologia},
  year    = {2016},
  doi     = {10.1590/s1980-5764-2016dn1002013},
  pmid    = {29213448},
  url     = {https://doi.org/10.1590/s1980-5764-2016dn1002013}
}

@article{reade2016-26975647,
  author  = {Reade, M. C. and Eastwood, G. M. and Bellomo, R. and Bailey, M. and Bersten, A. and Cheung, B. and Davies, A. and Delaney, A. and others},
  title   = {{Effect of Dexmedetomidine Added to Standard Care on Ventilator-Free Time in Patients With Agitated Delirium: A Randomized Clinical Trial}},
  journal = {JAMA},
  year    = {2016},
  doi     = {10.1001/jama.2016.2707},
  pmid    = {26975647},
  url     = {https://doi.org/10.1001/jama.2016.2707}
}

@article{wang2016-27010616,
  author  = {Wang, J. and Logovinsky, V. and Hendrix, S. B. and Stanworth, S. H. and Perdomo, C. and Xu, L. and Dhadda, S. and Do, I. and others},
  title   = {{ADCOMS: a composite clinical outcome for prodromal Alzheimer's disease trials}},
  journal = {Journal of neurology, neurosurgery, and psychiatry},
  year    = {2016},
  doi     = {10.1136/jnnp-2015-312383},
  pmid    = {27010616},
  url     = {https://doi.org/10.1136/jnnp-2015-312383}
}

@article{djaiani2016-26575144,
  author  = {Djaiani, G. and Silverton, N. and Fedorko, L. and Carroll, J. and Styra, R. and Rao, V. and Katznelson, R.},
  title   = {{Dexmedetomidine versus Propofol Sedation Reduces Delirium after Cardiac Surgery: A Randomized Controlled Trial}},
  journal = {Anesthesiology},
  year    = {2016},
  doi     = {10.1097/aln.0000000000000951},
  pmid    = {26575144},
  url     = {https://doi.org/10.1097/aln.0000000000000951}
}

@article{cummings2016-26822146,
  author  = {Cummings, J. L. and Zhong, K. and Kinney, J. W. and Heaney, C. and Moll-Tudla, J. and Joshi, A. and Pontecorvo, M. and Devous, M. and others},
  title   = {{Double-blind, placebo-controlled, proof-of-concept trial of bexarotene Xin moderate Alzheimer's disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2016},
  doi     = {10.1186/s13195-016-0173-2},
  pmid    = {26822146},
  url     = {https://doi.org/10.1186/s13195-016-0173-2}
}

@article{schneider2016-26771737,
  author  = {Schneider, L. S. and Frangakis, C. and Drye, L. T. and Devanand, D. P. and Marano, C. M. and Mintzer, J. and Mulsant, B. H. and Munro, C. A. and others},
  title   = {{Heterogeneity of Treatment Response to Citalopram for Patients With Alzheimer's Disease With Aggression or Agitation: The CitAD Randomized Clinical Trial}},
  journal = {The American journal of psychiatry},
  year    = {2016},
  doi     = {10.1176/appi.ajp.2015.15050648},
  pmid    = {26771737},
  url     = {https://doi.org/10.1176/appi.ajp.2015.15050648}
}

@article{mahgoub2016-26946981,
  author  = {Mahgoub, N. and Alexopoulos, G. S.},
  title   = {{Amyloid Hypothesis: Is There a Role for Antiamyloid Treatment in Late-Life Depression?}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2016},
  doi     = {10.1016/j.jagp.2015.12.003},
  pmid    = {26946981},
  url     = {https://doi.org/10.1016/j.jagp.2015.12.003}
}

@article{henderson2016-26795874,
  author  = {Henderson, E. J. and Lord, SR. and Brodie, M. A. and Gaunt, D. M. and Lawrence, A. D. and Close, J. C. and Whone, A. L. and others},
  title   = {{Rivastigmine for gait stability in patients with Parkinson's disease (ReSPonD): a randomised, double-blind, placebo-controlled, phase 2 trial}},
  journal = {The Lancet. Neurology},
  year    = {2016},
  doi     = {10.1016/s1474-4422(15)00389-0},
  pmid    = {26795874},
  url     = {https://doi.org/10.1016/s1474-4422(15)00389-0}
}

@article{sambamoorthi2016-27761472,
  author  = {Sambamoorthi, Usha and Deb, Arijita and Zhou, Steve and Garg, Rahul and Fan, Tao and Boss, Anders},
  title   = {{Rapid Acting Insulin Use and Persistence among Elderly Type 2 Diabetes Patients Adding RAI to Oral Antidiabetes Drug Regimens}},
  journal = {Journal of Diabetes Research},
  year    = {2016},
  doi     = {10.1155/2016/5374931},
  pmid    = {27761472},
  url     = {https://doi.org/10.1155/2016/5374931}
}

@article{chitnis2015-26705381,
  author  = {Chitnis, A.S. and Aparasu, Rajender R. and Chen, Hua and Kunik, Mark E. and Schulz, Paul Ernest and Johnson, Michael L.},
  title   = {{Use of Angiotensin-Converting Enzyme Inhibitors, Angiotensin Receptor Blockers, and Risk of Dementia in Heart Failure}},
  journal = {American Journal of Alzheimer s Disease \& Other Dementias®},
  year    = {2015},
  doi     = {10.1177/1533317515618799},
  pmid    = {26705381},
  url     = {https://doi.org/10.1177/1533317515618799}
}

@article{sanchez2016-26631687,
  author  = {Sánchez, A. and Marante-Moar, M. P. and Sarabia, C. and de Labra, C. and Lorenzo, T. and Maseda, A. and Millán-Calenti, J. C.},
  title   = {{Multisensory Stimulation as an Intervention Strategy for Elderly Patients With Severe Dementia: A Pilot Randomized Controlled Trial}},
  journal = {American journal of Alzheimer's disease and other dementias},
  year    = {2016},
  doi     = {10.1177/1533317515618801},
  pmid    = {26631687},
  url     = {https://doi.org/10.1177/1533317515618801}
}

@article{amieva2016-26572551,
  author  = {Amieva, H. and Robert, P. H. and Grandoulier, A. S. and Meillon, C. and De Rotrou, J. and Andrieu, S. and Berr, C. and Desgranges, B. and others},
  title   = {{Group and individual cognitive therapies in Alzheimer's disease: the ETNA3 randomized trial}},
  journal = {International psychogeriatrics},
  year    = {2016},
  doi     = {10.1017/s1041610215001830},
  pmid    = {26572551},
  url     = {https://doi.org/10.1017/s1041610215001830}
}

@article{henderson2015-26537053,
  author  = {Henderson, V. W. and Ala, T. and Sainani, K. L. and Bernstein, A. L. and Stephenson, B. S. and Rosen, A. C. and Farlow, M. R.},
  title   = {{Raloxifene for women with Alzheimer disease: A randomized controlled pilot trial}},
  journal = {Neurology},
  year    = {2015},
  doi     = {10.1212/wnl.0000000000002171},
  pmid    = {26537053},
  url     = {https://doi.org/10.1212/wnl.0000000000002171}
}

@article{coric2015-26414022,
  author  = {Coric, V. and Salloway, S. and van Dyck, C. H. and Dubois, B. and Andreasen, N. and Brody, M. and Curtis, C. and Soininen, H. and others},
  title   = {{Targeting Prodromal Alzheimer Disease With Avagacestat: A Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2015},
  doi     = {10.1001/jamaneurol.2015.0607},
  pmid    = {26414022},
  url     = {https://doi.org/10.1001/jamaneurol.2015.0607}
}

@article{turner2015-26362286,
  author  = {Turner, R. S. and Thomas, R. G. and Craft, S. and van Dyck, C. H. and Mintzer, J. and Reynolds, B. A. and Brewer, J. B. and Rissman, R. A. and others},
  title   = {{A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease}},
  journal = {Neurology},
  year    = {2015},
  doi     = {10.1212/wnl.0000000000002035},
  pmid    = {26362286},
  url     = {https://doi.org/10.1212/wnl.0000000000002035}
}

@article{cummings2015-26393847,
  author  = {Cummings, J. L. and Lyketsos, C. G. and Peskind, E. R. and Porsteinsson, A. P. and Mintzer, J. E. and Scharre, D. W. and De La Gandara, J. E. and Agronin, M. and others},
  title   = {{Effect of Dextromethorphan-Quinidine on Agitation in Patients With Alzheimer Disease Dementia: A Randomized Clinical Trial}},
  journal = {JAMA},
  year    = {2015},
  doi     = {10.1001/jama.2015.10214},
  pmid    = {26393847},
  url     = {https://doi.org/10.1001/jama.2015.10214}
}

@article{peters2016-26303700,
  author  = {Peters, M. E. and Vaidya, V. and Drye, L. T. and Devanand, D. P. and Mintzer, J. E. and Pollock, B. G. and Porsteinsson, A. P. and Rosenberg, P. B. and others},
  title   = {{Citalopram for the Treatment of Agitation in Alzheimer Dementia: Genetic Influences}},
  journal = {Journal of geriatric psychiatry and neurology},
  year    = {2016},
  doi     = {10.1177/0891988715601735},
  pmid    = {26303700},
  url     = {https://doi.org/10.1177/0891988715601735}
}

@article{chew2015-26305649,
  author  = {Chew, E. Y. and Clemons, T. E. and Agrón, E. and Launer, L. J. and Grodstein, F. and Bernstein, P. S.},
  title   = {{Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial}},
  journal = {JAMA},
  year    = {2015},
  doi     = {10.1001/jama.2015.9677},
  pmid    = {26305649},
  url     = {https://doi.org/10.1001/jama.2015.9677}
}

@article{lanedonovan2015-26152694,
  author  = {Lane-Donovan, C. and Philips, G. T. and Wasser, C. R. and Durakoglugil, M. S. and Masiulis, I. and Upadhaya, A. and Pohlkamp, T. and Coskun, C. and others},
  title   = {{Reelin protects against amyloid β toxicity in vivo}},
  journal = {Science signaling},
  year    = {2015},
  doi     = {10.1126/scisignal.aaa6674},
  pmid    = {26152694},
  url     = {https://doi.org/10.1126/scisignal.aaa6674}
}

@article{lenz2015-25973909,
  author  = {Lenz, R. A. and Pritchett, Y. L. and Berry, S. M. and Llano, D. A. and Han, S. and Berry, D. A. and Sadowsky, C. H. and Abi-Saab, W. M. and others},
  title   = {{Adaptive, dose-finding phase 2 trial evaluating the safety and efficacy of ABT-089 in mild to moderate Alzheimer disease}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2015},
  doi     = {10.1097/wad.0000000000000093},
  pmid    = {25973909},
  url     = {https://doi.org/10.1097/wad.0000000000000093}
}

@article{butchart2015-25934853,
  author  = {Butchart, J. and Brook, L. and Hopkins, V. and Teeling, J. and Püntener, U. and Culliford, D. and Sharples, R. and Sharif, S. and others},
  title   = {{Etanercept in Alzheimer disease: A randomized, placebo-controlled, double-blind, phase 2 trial}},
  journal = {Neurology},
  year    = {2015},
  doi     = {10.1212/wnl.0000000000001617},
  pmid    = {25934853},
  url     = {https://doi.org/10.1212/wnl.0000000000001617}
}

@article{nygaard2015-25874001,
  author  = {Nygaard, H. B. and Wagner, A. F. and Bowen, G. S. and Good, S. P. and MacAvoy, M. G. and Strittmatter, K. A. and Kaufman, A. C. and Rosenberg, B. J. and others},
  title   = {{A phase Ib multiple ascending dose study of the safety, tolerability, and central nervous system availability of AZD0530 (saracatinib) in Alzheimer's disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2015},
  doi     = {10.1186/s13195-015-0119-0},
  pmid    = {25874001},
  url     = {https://doi.org/10.1186/s13195-015-0119-0}
}

@article{birks2015-25858345,
  author  = {Birks, J. S. and Grimley Evans, J.},
  title   = {{Rivastigmine for Alzheimer's disease}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2015},
  doi     = {10.1002/14651858.cd001191.pub3},
  pmid    = {25858345},
  url     = {https://doi.org/10.1002/14651858.cd001191.pub3}
}

@article{curtis2015-25622185,
  author  = {Curtis, C. and Gamez, J. E. and Singh, U. and Sadowsky, C. H. and Villena, T. and Sabbagh, M. N. and Beach, T. G. and Duara, R. and others},
  title   = {{Phase 3 trial of flutemetamol labeled with radioactive fluorine 18 imaging and neuritic plaque density}},
  journal = {JAMA neurology},
  year    = {2015},
  doi     = {10.1001/jamaneurol.2014.4144},
  pmid    = {25622185},
  url     = {https://doi.org/10.1001/jamaneurol.2014.4144}
}

@article{sabogalguaqueta2015-25666032,
  author  = {Sabogal-Guáqueta, A. M. and Muñoz-Manco, J. I. and Ramírez-Pineda, JR. and Lamprea-Rodriguez, M. and Osorio, E. and Cardona-Gómez, G. P.},
  title   = {{The flavonoid quercetin ameliorates Alzheimer's disease pathology and protects cognitive and emotional function in aged triple transgenic Alzheimer's disease model mice}},
  journal = {Neuropharmacology},
  year    = {2015},
  doi     = {10.1016/j.neuropharm.2015.01.027},
  pmid    = {25666032},
  url     = {https://doi.org/10.1016/j.neuropharm.2015.01.027}
}

@article{rouch2015-25700645,
  author  = {Rouch, L. and Cestac, P. and Hanon, O. and Cool, C. and Helmer, C. and Bouhanick, B. and Chamontin, B. and Dartigues, J. F. and others},
  title   = {{Antihypertensive drugs, prevention of cognitive decline and dementia: a systematic review of observational studies, randomized controlled trials and meta-analyses, with discussion of potential mechanisms}},
  journal = {CNS drugs},
  year    = {2015},
  doi     = {10.1007/s40263-015-0230-6},
  pmid    = {25700645},
  url     = {https://doi.org/10.1007/s40263-015-0230-6}
}

@article{soto2015-25226218,
  author  = {Soto, M. and Andrieu, S. and Nourhashemi, F. and Ousset, P. J. and Ballard, C. and Robert, P. and Vellas, B. and Lyketsos, C. G. and others},
  title   = {{Medication development for agitation and aggression in Alzheimer disease: review and discussion of recent randomized clinical trial design}},
  journal = {International psychogeriatrics},
  year    = {2015},
  doi     = {10.1017/s1041610214001720},
  pmid    = {25226218},
  url     = {https://doi.org/10.1017/s1041610214001720}
}

@article{miguelalvarez2015-25644018,
  author  = {Miguel-Álvarez, M. and Santos-Lozano, A. and Sanchis-Gomar, F. and Fiuza-Luces, C. and Pareja-Galeano, H. and Garatachea, N. and Lucia, A.},
  title   = {{Non-steroidal anti-inflammatory drugs as a treatment for Alzheimer's disease: a systematic review and meta-analysis of treatment effect}},
  journal = {Drugs \& aging},
  year    = {2015},
  doi     = {10.1007/s40266-015-0239-z},
  pmid    = {25644018},
  url     = {https://doi.org/10.1007/s40266-015-0239-z}
}

@article{pardini2015-25592742,
  author  = {Pardini, M. and Serrati, C. and Guida, S. and Mattei, C. and Abate, L. and Massucco, D. and Sassos, D. and Amore, M. and others},
  title   = {{Souvenaid reduces behavioral deficits and improves social cognition skills in frontotemporal dementia: a proof-of-concept study}},
  journal = {Neuro-degenerative diseases},
  year    = {2015},
  doi     = {10.1159/000369811},
  pmid    = {25592742},
  url     = {https://doi.org/10.1159/000369811}
}

@article{rowe2015-25567553,
  author  = {Rowe, A. R. and Mercer, L. and Casetti, V. and Sendt, K. V. and Giaroli, G. and Shergill, S. S. and Tracy, D. K.},
  title   = {{Dementia praecox redux: a systematic review of the nicotinic receptor as a target for cognitive symptoms of schizophrenia}},
  journal = {Journal of psychopharmacology (Oxford, England)},
  year    = {2015},
  doi     = {10.1177/0269881114564096},
  pmid    = {25567553},
  url     = {https://doi.org/10.1177/0269881114564096}
}

@article{rigacci2015-26092624,
  author  = {Rigacci, S.},
  title   = {{Olive Oil Phenols as Promising Multi-targeting Agents Against Alzheimer's Disease}},
  journal = {Advances in experimental medicine and biology},
  year    = {2015},
  doi     = {10.1007/978-3-319-18365-7_1},
  pmid    = {26092624},
  url     = {https://doi.org/10.1007/978-3-319-18365-7_1}
}

@article{schneeberger2015-29231230,
  author  = {Schneeberger, A. and Hendrix, S. and Mandler, M. and Ellison, N. and Bürger, V. and Brunner, M. and Frölich, L. and Mimica, N. and others},
  title   = {{Results from a Phase II Study to Assess the Clinical and Immunological Activity of AFFITOPE® AD02 in Patients with Early Alzheimer's Disease}},
  journal = {The journal of prevention of Alzheimer's disease},
  year    = {2015},
  doi     = {10.14283/jpad.2015.63},
  pmid    = {29231230},
  url     = {https://doi.org/10.14283/jpad.2015.63}
}

@article{teich2015-25575647,
  author  = {Teich, A. F. and Nicholls, R. E. and Puzzo, D. and Fiorito, J. and Purgatorio, R. and Fa', M. and Arancio, O.},
  title   = {{Synaptic therapy in Alzheimer's disease: a CREB-centric approach}},
  journal = {Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics},
  year    = {2015},
  doi     = {10.1007/s13311-014-0327-5},
  pmid    = {25575647},
  url     = {https://doi.org/10.1007/s13311-014-0327-5}
}

@article{ballard2015-25523285,
  author  = {Ballard, C. and Thomas, A. and Gerry, S. and Yu, L. M. and Aarsland, D. and Merritt, C. and Corbett, A. and Davison, C. and others},
  title   = {{A double-blind randomized placebo-controlled withdrawal trial comparing memantine and antipsychotics for the long-term treatment of function and neuropsychiatric symptoms in people with Alzheimer's disease (MAIN-AD)}},
  journal = {Journal of the American Medical Directors Association},
  year    = {2015},
  doi     = {10.1016/j.jamda.2014.11.002},
  pmid    = {25523285},
  url     = {https://doi.org/10.1016/j.jamda.2014.11.002}
}

@article{sadhu2014-25316430,
  author  = {Sadhu, A. and Upadhyay, P. and Agrawal, A. and Ilango, K. and Karmakar, D. and Singh, G. P. and Dubey, G. P.},
  title   = {{Management of cognitive determinants in senile dementia of Alzheimer's type: therapeutic potential of a novel polyherbal drug product}},
  journal = {Clinical drug investigation},
  year    = {2014},
  doi     = {10.1007/s40261-014-0235-9},
  pmid    = {25316430},
  url     = {https://doi.org/10.1007/s40261-014-0235-9}
}

@article{endres2014-25344383,
  author  = {Endres, K. and Fahrenholz, F. and Lotz, J. and Hiemke, C. and Teipel, S. and Lieb, K. and Tüscher, O. and Fellgiebel, A.},
  title   = {{Increased CSF APPs-α levels in patients with Alzheimer disease treated with acitretin}},
  journal = {Neurology},
  year    = {2014},
  doi     = {10.1212/wnl.0000000000001017},
  pmid    = {25344383},
  url     = {https://doi.org/10.1212/wnl.0000000000001017}
}

@article{liang2014-25294055,
  author  = {Liang, J. and Li, F. and Wei, C. and Song, H. and Wu, L. and Tang, Y. and Jia, J.},
  title   = {{Rationale and design of a multicenter, phase 2 clinical trial to investigate the efficacy of traditional Chinese medicine SaiLuoTong in vascular dementia}},
  journal = {Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association},
  year    = {2014},
  doi     = {10.1016/j.jstrokecerebrovasdis.2014.06.005},
  pmid    = {25294055},
  url     = {https://doi.org/10.1016/j.jstrokecerebrovasdis.2014.06.005}
}

@article{figueiro2014-25246779,
  author  = {Figueiro, M. G. and Plitnick, B. A. and Lok, A. and Jones, G. E. and Higgins, P. and Hornick, T. R. and Rea, M. S.},
  title   = {{Tailored lighting intervention improves measures of sleep, depression, and agitation in persons with Alzheimer's disease and related dementia living in long-term care facilities}},
  journal = {Clinical interventions in aging},
  year    = {2014},
  doi     = {10.2147/cia.s68557},
  pmid    = {25246779},
  url     = {https://doi.org/10.2147/cia.s68557}
}

@article{billiotidegage2014-25208536,
  author  = {Billioti de Gage, S. and Moride, Y. and Ducruet, T. and Kurth, T. and Verdoux, H. and Tournier, M. and Pariente, A. and Bégaud, B.},
  title   = {{Benzodiazepine use and risk of Alzheimer's disease: case-control study}},
  journal = {BMJ (Clinical research ed.)},
  year    = {2014},
  doi     = {10.1136/bmj.g5205},
  pmid    = {25208536},
  url     = {https://doi.org/10.1136/bmj.g5205}
}

@article{ooms2014-24887018,
  author  = {Ooms, S. and Overeem, S. and Besse, K. and Rikkert, M. O. and Verbeek, M. and Claassen, J. A.},
  title   = {{Effect of 1 night of total sleep deprivation on cerebrospinal fluid β-amyloid 42 in healthy middle-aged men: a randomized clinical trial}},
  journal = {JAMA neurology},
  year    = {2014},
  doi     = {10.1001/jamaneurol.2014.1173},
  pmid    = {24887018},
  url     = {https://doi.org/10.1001/jamaneurol.2014.1173}
}

@article{navamesa2014-24987334,
  author  = {Nava-Mesa, M. O. and Jiménez-Díaz, L. and Yajeya, J. and Navarro-Lopez, J. D.},
  title   = {{GABAergic neurotransmission and new strategies of neuromodulation to compensate synaptic dysfunction in early stages of Alzheimer's disease}},
  journal = {Frontiers in cellular neuroscience},
  year    = {2014},
  doi     = {10.3389/fncel.2014.00167},
  pmid    = {24987334},
  url     = {https://doi.org/10.3389/fncel.2014.00167}
}

@article{mokhber2014-24955552,
  author  = {Mokhber, N. and Abdollahian, E. and Soltanifar, A. and Samadi, R. and Saghebi, A. and Haghighi, M. B. and Azarpazhooh, A.},
  title   = {{Comparison of sertraline, venlafaxine and desipramine effects on depression, cognition and the daily living activities in Alzheimer patients}},
  journal = {Pharmacopsychiatry},
  year    = {2014},
  doi     = {10.1055/s-0034-1377041},
  pmid    = {24955552},
  url     = {https://doi.org/10.1055/s-0034-1377041}
}

@article{caramelli2014-24964105,
  author  = {Caramelli, P. and Laks, J. and Palmini, A. L. and Nitrini, R. and Chaves, M. L. and Forlenza, O. V. and Vale Fde, A. and Barbosa, M. T. and others},
  title   = {{Effects of galantamine and galantamine combined with nimodipine on cognitive speed and quality of life in mixed dementia: a 24-week, randomized, placebo-controlled exploratory trial (the REMIX study)}},
  journal = {Arquivos de neuro-psiquiatria},
  year    = {2014},
  doi     = {10.1590/0004-282x20140055},
  pmid    = {24964105},
  url     = {https://doi.org/10.1590/0004-282x20140055}
}

@article{quintanahernandez2014-24880524,
  author  = {Quintana Hernández, D. J. and Miró Barrachina, M. T. and Ibáñez Fernández, I. and del Pino, A. S. and Rodríguez, Jr., García and Hernández, JR.},
  title   = {{[Effects of a neuropsychology program based on mindfulness on Alzheimer's disease: randomized double-blind clinical study]}},
  journal = {Revista espanola de geriatria y gerontologia},
  year    = {2014},
  doi     = {10.1016/j.regg.2014.03.002},
  pmid    = {24880524},
  url     = {https://doi.org/10.1016/j.regg.2014.03.002}
}

@article{wang2015-24828899,
  author  = {Wang, H. F. and Yu, J. T. and Tang, S. W. and Jiang, T. and Tan, C. C. and Meng, X. F. and Wang, C. and Tan, M. S. and others},
  title   = {{Efficacy and safety of cholinesterase inhibitors and memantine in cognitive impairment in Parkinson's disease, Parkinson's disease dementia, and dementia with Lewy bodies: systematic review with meta-analysis and trial sequential analysis}},
  journal = {Journal of neurology, neurosurgery, and psychiatry},
  year    = {2015},
  doi     = {10.1136/jnnp-2014-307659},
  pmid    = {24828899},
  url     = {https://doi.org/10.1136/jnnp-2014-307659}
}

@article{galasko2014-24696507,
  author  = {Galasko, D. and Bell, J. and Mancuso, J. Y. and Kupiec, J. W. and Sabbagh, M. N. and van Dyck, C. and Thomas, R. G. and Aisen, P. S. and others},
  title   = {{Clinical trial of an inhibitor of RAGE-Aβ interactions in Alzheimer disease}},
  journal = {Neurology},
  year    = {2014},
  doi     = {10.1212/wnl.0000000000000364},
  pmid    = {24696507},
  url     = {https://doi.org/10.1212/wnl.0000000000000364}
}

@article{doraiswamy2014-24614494,
  author  = {Doraiswamy, P. M. and Sperling, R. A. and Johnson, K. and Reiman, E. M. and Wong, T. Z. and Sabbagh, M. N. and Sadowsky, C. H. and Fleisher, A. S. and others},
  title   = {{Florbetapir F 18 amyloid PET and 36-month cognitive decline: a prospective multicenter study}},
  journal = {Molecular psychiatry},
  year    = {2014},
  doi     = {10.1038/mp.2014.9},
  pmid    = {24614494},
  url     = {https://doi.org/10.1038/mp.2014.9}
}

@article{viayna2014-24568372,
  author  = {Viayna, E. and Sola, I. and Bartolini, M. and De Simone, A. and Tapia-Rojas, C. and Serrano, F. G. and Sabaté, R. and Juárez-Jiménez, J. and others},
  title   = {{Synthesis and multitarget biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agents}},
  journal = {Journal of medicinal chemistry},
  year    = {2014},
  doi     = {10.1021/jm401824w},
  pmid    = {24568372},
  url     = {https://doi.org/10.1021/jm401824w}
}

@article{aso2014-24634659,
  author  = {Aso, E. and Ferrer, I.},
  title   = {{Cannabinoids for treatment of Alzheimer's disease: moving toward the clinic}},
  journal = {Frontiers in pharmacology},
  year    = {2014},
  doi     = {10.3389/fphar.2014.00037},
  pmid    = {24634659},
  url     = {https://doi.org/10.3389/fphar.2014.00037}
}

@article{porsteinsson2014-24549548,
  author  = {Porsteinsson, A. P. and Drye, L. T. and Pollock, B. G. and Devanand, D. P. and Frangakis, C. and Ismail, Z. and Marano, C. and Meinert, C. L. and others},
  title   = {{Effect of citalopram on agitation in Alzheimer disease: the CitAD randomized clinical trial}},
  journal = {JAMA},
  year    = {2014},
  doi     = {10.1001/jama.2014.93},
  pmid    = {24549548},
  url     = {https://doi.org/10.1001/jama.2014.93}
}

@article{doody2014-24450890,
  author  = {Doody, Rachelle Smith and Thomas, Ronald G. and Farlow, Martin Rhys and Iwatsubo, Takeshi and Vellas, Bruno J. and Joffe, Steven and Kieburtz, Karl D. and Raman, Rema and Sun, Xiaoying and Aisen, Paul S. S. and Siemers, Eric and Liu‐Seifert, Hong and Mohs, Richard C.},
  title   = {{Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease}},
  journal = {New England Journal of Medicine},
  year    = {2014},
  doi     = {10.1056/nejmoa1312889},
  pmid    = {24450890},
  url     = {https://doi.org/10.1056/nejmoa1312889}
}

@article{burstein2014-24423155,
  author  = {Burstein, A. H. and Grimes, I. and Galasko, D. R. and Aisen, P. S. and Sabbagh, M. and Mjalli, A. M.},
  title   = {{Effect of TTP488 in patients with mild to moderate Alzheimer's disease}},
  journal = {BMC neurology},
  year    = {2014},
  doi     = {10.1186/1471-2377-14-12},
  pmid    = {24423155},
  url     = {https://doi.org/10.1186/1471-2377-14-12}
}

@article{camargos2014-24495406,
  author  = {Camargos, E. F. and Louzada, L. L. and Quintas, J. L. and Naves, J. O. and Louzada, F. M. and Nóbrega, O. T.},
  title   = {{Trazodone improves sleep parameters in Alzheimer disease patients: a randomized, double-blind, and placebo-controlled study}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2014},
  doi     = {10.1016/j.jagp.2013.12.174},
  pmid    = {24495406},
  url     = {https://doi.org/10.1016/j.jagp.2013.12.174}
}

@article{shinto2014-24077434,
  author  = {Shinto, L. and Quinn, J. and Montine, T. and Dodge, H. H. and Woodward, W. and Baldauf-Wagner, S. and Waichunas, D. and Bumgarner, L. and others},
  title   = {{A randomized placebo-controlled pilot trial of omega-3 fatty acids and alpha lipoic acid in Alzheimer's disease}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2014},
  doi     = {10.3233/jad-130722},
  pmid    = {24077434},
  url     = {https://doi.org/10.3233/jad-130722}
}

@article{talbot2014-24640977,
  author  = {Talbot, K.},
  title   = {{Brain insulin resistance in Alzheimer's disease and its potential treatment with GLP-1 analogs}},
  journal = {Neurodegenerative disease management},
  year    = {2014},
  doi     = {10.2217/nmt.13.73},
  pmid    = {24640977},
  url     = {https://doi.org/10.2217/nmt.13.73}
}

@article{dysken2014-24381967,
  author  = {Dysken, M. W. and Sano, M. and Asthana, S. and Vertrees, J. E. and Pallaki, M. and Llorente, M. and Love, S. and Schellenberg, G. D. and others},
  title   = {{Effect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trial}},
  journal = {JAMA},
  year    = {2014},
  doi     = {10.1001/jama.2013.282834},
  pmid    = {24381967},
  url     = {https://doi.org/10.1001/jama.2013.282834}
}

@article{flynnlongmire2014-24314887,
  author  = {Flynn Longmire, C. V. and Drye, L. T. and Frangakis, C. E. and Martin, B. K. and Meinert, C. L. and Mintzer, J. E. and Munro, C. A. and Porsteinsson, A. P. and others},
  title   = {{Is sertraline treatment or depression remission in depressed Alzheimer patients associated with improved caregiver well being? Depression in Alzheimer's Disease Study 2}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2014},
  doi     = {10.1016/j.jagp.2013.02.014},
  pmid    = {24314887},
  url     = {https://doi.org/10.1016/j.jagp.2013.02.014}
}

@article{olazaran2014-24898637,
  author  = {Olazarán, J. and González, B. and Osa-Ruiz, E. and Felipe-Ruiz, S. and Boyano, I. and Fontani, V. and Castagna, A. and Mendoza, C. and others},
  title   = {{Motor effects of radio electric asymmetric conveyer in Alzheimer's disease: results from a cross-over trial}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2014},
  doi     = {10.3233/jad-140417},
  pmid    = {24898637},
  url     = {https://doi.org/10.3233/jad-140417}
}

@article{salloway2014-24450891,
  author  = {Salloway, S. and Sperling, R. and Fox, N. C. and Blennow, K. and Klunk, W. and Raskind, M. and Sabbagh, M. and Honig, L. S. and others},
  title   = {{Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease}},
  journal = {The New England journal of medicine},
  year    = {2014},
  doi     = {10.1056/nejmoa1304839},
  pmid    = {24450891},
  url     = {https://doi.org/10.1056/nejmoa1304839}
}

@article{liu2014-24468471,
  author  = {Liu, R. and Li, J. Z. and Song, J. K. and Zhou, D. and Huang, C. and Bai, X. Y. and Xie, T. and Zhang, X. and others},
  title   = {{Pinocembrin improves cognition and protects the neurovascular unit in Alzheimer related deficits}},
  journal = {Neurobiology of aging},
  year    = {2014},
  doi     = {10.1016/j.neurobiolaging.2013.12.031},
  pmid    = {24468471},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2013.12.031}
}

@article{wang2013-23948786,
  author  = {Wang, T. and Huang, Q. and Reiman, E. M. and Chen, K. and Li, X. and Li, G. and Lin, Z. and Li, C. and others},
  title   = {{Effects of memantine on clinical ratings, fluorodeoxyglucose positron emission tomography measurements, and cerebrospinal fluid assays in patients with moderate to severe Alzheimer dementia: a 24-week, randomized, clinical trial}},
  journal = {Journal of clinical psychopharmacology},
  year    = {2013},
  doi     = {10.1097/jcp.0b013e31829a876a},
  pmid    = {23948786},
  url     = {https://doi.org/10.1097/jcp.0b013e31829a876a}
}

@article{lin2014-24074637,
  author  = {Lin, C. H. and Chen, P. K. and Chang, Y. C. and Chuo, L. J. and Chen, Y. S. and Tsai, G. E. and Lane, H. Y.},
  title   = {{Benzoate, a D-amino acid oxidase inhibitor, for the treatment of early-phase Alzheimer disease: a randomized, double-blind, placebo-controlled trial}},
  journal = {Biological psychiatry},
  year    = {2014},
  doi     = {10.1016/j.biopsych.2013.08.010},
  pmid    = {24074637},
  url     = {https://doi.org/10.1016/j.biopsych.2013.08.010}
}

@article{yang2013-24086396,
  author  = {Yang, G. and Wang, Y. and Tian, J. and Liu, J. P.},
  title   = {{Huperzine A for Alzheimer's disease: a systematic review and meta-analysis of randomized clinical trials}},
  journal = {PloS one},
  year    = {2013},
  doi     = {10.1371/journal.pone.0074916},
  pmid    = {24086396},
  url     = {https://doi.org/10.1371/journal.pone.0074916}
}

@article{zhang2014-24022672,
  author  = {Zhang, Z. and Liu, X. and Schroeder, J. P. and Chan, C. B. and Song, M. and Yu, S. P. and Weinshenker, D. and Ye, K.},
  title   = {{7,8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer's disease}},
  journal = {Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology},
  year    = {2014},
  doi     = {10.1038/npp.2013.243},
  pmid    = {24022672},
  url     = {https://doi.org/10.1038/npp.2013.243}
}

@article{rosenberg2013-24021498,
  author  = {Rosenberg, P. B. and Lanctôt, K. L. and Drye, L. T. and Herrmann, N. and Scherer, R. W. and Bachman, D. L. and Mintzer, J. E. and {ADMET Investigators}},
  title   = {{Safety and efficacy of methylphenidate for apathy in Alzheimer's disease: a randomized, placebo-controlled trial}},
  journal = {The Journal of clinical psychiatry},
  year    = {2013},
  doi     = {10.4088/jcp.12m08099},
  pmid    = {24021498},
  url     = {https://doi.org/10.4088/jcp.12m08099}
}

@article{doody2013-23883379,
  author  = {Doody, Rachelle Smith and Raman, Rema and Farlow, Martin Rhys and Iwatsubo, Takeshi and Vellas, Bruno J. and Joffe, Steven and Kieburtz, Karl D. and He, Feng and Sun, Xiaoying and Thomas, Ronald G. and Aisen, Paul S. S. and Siemers, Eric and Sethuraman, Gopalan and Mohs, Richard C.},
  title   = {{A Phase 3 Trial of Semagacestat for Treatment of Alzheimer's Disease}},
  journal = {New England Journal of Medicine},
  year    = {2013},
  doi     = {10.1056/nejmoa1210951},
  pmid    = {23883379},
  url     = {https://doi.org/10.1056/nejmoa1210951}
}

@article{bergamaschi2013-23784727,
  author  = {Bergamaschi, S. and Arcara, G. and Calza, A. and Villani, D. and Orgeta, V. and Mondini, S.},
  title   = {{One-year repeated cycles of cognitive training (CT) for Alzheimer's disease}},
  journal = {Aging clinical and experimental research},
  year    = {2013},
  doi     = {10.1007/s40520-013-0065-2},
  pmid    = {23784727},
  url     = {https://doi.org/10.1007/s40520-013-0065-2}
}

@article{douaud2013-23690582,
  author  = {Douaud, G. and Refsum, H. and de Jager, C. A. and Jacoby, R. and Nichols, T. E. and Smith, S. M. and Smith, A. D.},
  title   = {{Preventing Alzheimer's disease-related gray matter atrophy by B-vitamin treatment}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2013},
  doi     = {10.1073/pnas.1301816110},
  pmid    = {23690582},
  url     = {https://doi.org/10.1073/pnas.1301816110}
}

@article{pitkala2013-23589097,
  author  = {Pitkälä, K. H. and Pöysti, M. M. and Laakkonen, M. L. and Tilvis, R. S. and Savikko, N. and Kautiainen, H. and Strandberg, T. E.},
  title   = {{Effects of the Finnish Alzheimer disease exercise trial (FINALEX): a randomized controlled trial}},
  journal = {JAMA internal medicine},
  year    = {2013},
  doi     = {10.1001/jamainternmed.2013.359},
  pmid    = {23589097},
  url     = {https://doi.org/10.1001/jamainternmed.2013.359}
}

@article{stanley2013-23567399,
  author  = {Stanley, M. A. and Calleo, J. and Bush, A. L. and Wilson, N. and Snow, A. L. and Kraus-Schuman, C. and Paukert, A. L. and Petersen, N. J. and others},
  title   = {{The peaceful mind program: a pilot test of a cognitive-behavioral therapy-based intervention for anxious patients with dementia}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2013},
  doi     = {10.1016/j.jagp.2013.01.007},
  pmid    = {23567399},
  url     = {https://doi.org/10.1016/j.jagp.2013.01.007}
}

@article{volak2013-22725836,
  author  = {Volak, L. P. and Hanley, M. J. and Masse, G. and Hazarika, S. and Harmatz, J. S. and Badmaev, V. and Majeed, M. and Greenblatt, D. J. and others},
  title   = {{Effect of a herbal extract containing curcumin and piperine on midazolam, flurbiprofen and paracetamol (acetaminophen) pharmacokinetics in healthy volunteers}},
  journal = {British journal of clinical pharmacology},
  year    = {2013},
  doi     = {10.1111/j.1365-2125.2012.04364.x},
  pmid    = {22725836},
  url     = {https://doi.org/10.1111/j.1365-2125.2012.04364.x}
}

@article{johnson2013-23375563,
  author  = {Johnson, K. A. and Sperling, R. A. and Gidicsin, C. M. and Carmasin, J. S. and Maye, J. E. and Coleman, R. E. and Reiman, E. M. and Sabbagh, M. N. and others},
  title   = {{Florbetapir (F18-AV-45) PET to assess amyloid burden in Alzheimer's disease dementia, mild cognitive impairment, and normal aging}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2013},
  doi     = {10.1016/j.jalz.2012.10.007},
  pmid    = {23375563},
  url     = {https://doi.org/10.1016/j.jalz.2012.10.007}
}

@article{drye2013-23567407,
  author  = {Drye, L. T. and Scherer, R. W. and Lanctôt, K. L. and Rosenberg, P. B. and Herrmann, N. and Bachman, D. and Mintzer, J. E. and {ADMET Research Group}},
  title   = {{Designing a trial to evaluate potential treatments for apathy in dementia: the apathy in dementia methylphenidate trial (ADMET)}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2013},
  doi     = {10.1016/j.jagp.2012.12.018},
  pmid    = {23567407},
  url     = {https://doi.org/10.1016/j.jagp.2012.12.018}
}

@article{aso2013-23515018,
  author  = {Aso, E. and Juvés, S. and Maldonado, R. and Ferrer, I.},
  title   = {{CB2 cannabinoid receptor agonist ameliorates Alzheimer-like phenotype in AβPP/PS1 mice}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2013},
  doi     = {10.3233/jad-130137},
  pmid    = {23515018},
  url     = {https://doi.org/10.3233/jad-130137}
}

@article{landen2013-23334070,
  author  = {Landen, J. W. and Zhao, Q. and Cohen, S. and Borrie, M. and Woodward, M. and Billing, C. B. and Bales, K. and Alvey, C. and others},
  title   = {{Safety and pharmacology of a single intravenous dose of ponezumab in subjects with mild-to-moderate Alzheimer disease: a phase I, randomized, placebo-controlled, double-blind, dose-escalation study}},
  journal = {Clinical neuropharmacology},
  year    = {2013},
  doi     = {10.1097/wnf.0b013e31827db49b},
  pmid    = {23334070},
  url     = {https://doi.org/10.1097/wnf.0b013e31827db49b}
}

@article{munro2012-23032478,
  author  = {Munro, C. A. and Longmire, C. F. and Drye, L. T. and Martin, B. K. and Frangakis, C. E. and Meinert, C. L. and Mintzer, J. E. and Porsteinsson, A. P. and others},
  title   = {{Cognitive outcomes after sertaline treatment in patients with depression of Alzheimer disease}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2012},
  doi     = {10.1097/jgp.0b013e31826ce4c5},
  pmid    = {23032478},
  url     = {https://doi.org/10.1097/jgp.0b013e31826ce4c5}
}

@article{solomon2012-22631442,
  author  = {Solomon, A. and Akenine, U. and Andreasen, N. and Mangialasche, F. and Wimo, A. and Jelic, V. and Kivipelto, M. and Winblad, B.},
  title   = {{Practical lessons from amyloid immunotherapy trials in Alzheimer disease}},
  journal = {Current Alzheimer research},
  year    = {2012},
  doi     = {10.2174/156720512804142958},
  pmid    = {22631442},
  url     = {https://doi.org/10.2174/156720512804142958}
}

@article{cai2013-23183138,
  author  = {Cai, X. and Campbell, N. and Khan, B. and Callahan, C. and Boustani, M.},
  title   = {{Long-term anticholinergic use and the aging brain}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2013},
  doi     = {10.1016/j.jalz.2012.02.005},
  pmid    = {23183138},
  url     = {https://doi.org/10.1016/j.jalz.2012.02.005}
}

@article{chen2012-23122958,
  author  = {Chen, R. and Zhang, J. and Wu, Y. and Wang, D. and Feng, G. and Tang, Y. P. and Teng, Z. and Chen, C.},
  title   = {{Monoacylglycerol lipase is a therapeutic target for Alzheimer's disease}},
  journal = {Cell reports},
  year    = {2012},
  doi     = {10.1016/j.celrep.2012.09.030},
  pmid    = {23122958},
  url     = {https://doi.org/10.1016/j.celrep.2012.09.030}
}

@article{coric2012-22892585,
  author  = {Coric, V. and van Dyck, C. H. and Salloway, S. and Andreasen, N. and Brody, M. and Richter, R. W. and Soininen, H. and Thein, S. and others},
  title   = {{Safety and tolerability of the γ-secretase inhibitor avagacestat in a phase 2 study of mild to moderate Alzheimer disease}},
  journal = {Archives of neurology},
  year    = {2012},
  doi     = {10.1001/archneurol.2012.2194},
  pmid    = {22892585},
  url     = {https://doi.org/10.1001/archneurol.2012.2194}
}

@article{shao2012-23100399,
  author  = {Shao, H. and Breitner, J. C. and Whitmer, R. A. and Wang, J. and Hayden, K. and Wengreen, H. and Corcoran, C. and Tschanz, J. and others},
  title   = {{Hormone therapy and Alzheimer disease dementia: new findings from the Cache County Study}},
  journal = {Neurology},
  year    = {2012},
  doi     = {10.1212/wnl.0b013e318271f823},
  pmid    = {23100399},
  url     = {https://doi.org/10.1212/wnl.0b013e318271f823}
}

@article{jeppsson2012-23048024,
  author  = {Jeppsson, F. and Eketjäll, S. and Janson, J. and Karlström, S. and Gustavsson, S. and Olsson, L. L. and Radesäter, A. C. and Ploeger, B. and others},
  title   = {{Discovery of AZD3839, a potent and selective BACE1 inhibitor clinical candidate for the treatment of Alzheimer disease}},
  journal = {The Journal of biological chemistry},
  year    = {2012},
  doi     = {10.1074/jbc.m112.409110},
  pmid    = {23048024},
  url     = {https://doi.org/10.1074/jbc.m112.409110}
}

@article{egefjord2012-23158895,
  author  = {Egefjord, L. and Gejl, M. and Møller, A. and Brændgaard, H. and Gottrup, H. and Antropova, O. and Møller, N. and Poulsen, H. E. and others},
  title   = {{Effects of liraglutide on neurodegeneration, blood flow and cognition in Alzheimer´s disease - protocol for a controlled, randomized double-blinded trial}},
  journal = {Danish medical journal},
  year    = {2012},
  pmid    = {23158895}
}

@article{russ2012-22972133,
  author  = {Russ, T. C. and Morling, JR.},
  title   = {{Cholinesterase inhibitors for mild cognitive impairment}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2012},
  doi     = {10.1002/14651858.cd009132.pub2},
  pmid    = {22972133},
  url     = {https://doi.org/10.1002/14651858.cd009132.pub2}
}

@article{steinberg2012-22952071,
  author  = {Steinberg, M. and Lyketsos, C. G.},
  title   = {{Atypical antipsychotic use in patients with dementia: managing safety concerns}},
  journal = {The American journal of psychiatry},
  year    = {2012},
  doi     = {10.1176/appi.ajp.2012.12030342},
  pmid    = {22952071},
  url     = {https://doi.org/10.1176/appi.ajp.2012.12030342}
}

@article{dubois2012-22915447,
  author  = {Dubois, B. and Tolosa, E. and Katzenschlager, R. and Emre, M. and Lees, A. J. and Schumann, G. and Pourcher, E. and Gray, J. and others},
  title   = {{Donepezil in Parkinson's disease dementia: a randomized, double-blind efficacy and safety study}},
  journal = {Movement disorders : official journal of the Movement Disorder Society},
  year    = {2012},
  doi     = {10.1002/mds.25098},
  pmid    = {22915447},
  url     = {https://doi.org/10.1002/mds.25098}
}

@article{oules2012-22915123,
  author  = {Oulès, B. and Del Prete, D. and Greco, B. and Zhang, X. and Lauritzen, I. and Sevalle, J. and Moreno, S. and Paterlini-Bréchot, P. and others},
  title   = {{Ryanodine receptor blockade reduces amyloid-β load and memory impairments in Tg2576 mouse model of Alzheimer disease}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2012},
  doi     = {10.1523/jneurosci.0875-12.2012},
  pmid    = {22915123},
  url     = {https://doi.org/10.1523/jneurosci.0875-12.2012}
}

@article{madigan2012-22877803,
  author  = {Madigan, D. and Sigelman, D. W. and Mayer, J. W. and Furberg, C. D. and Avorn, J.},
  title   = {{Under-reporting of cardiovascular events in the rofecoxib Alzheimer disease studies}},
  journal = {American heart journal},
  year    = {2012},
  doi     = {10.1016/j.ahj.2012.05.002},
  pmid    = {22877803},
  url     = {https://doi.org/10.1016/j.ahj.2012.05.002}
}

@article{yu2012-22805083,
  author  = {Yu, L. and Lin, S. M. and Zhou, R. Q. and Tang, W. J. and Huang, P. X. and Dong, Y. and Wang, J. and Yu, Z. H. and others},
  title   = {{[Chinese herbal medicine for patients with mild to moderate Alzheimer disease based on syndrome differentiation: a randomized controlled trial]}},
  journal = {Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine},
  year    = {2012},
  doi     = {10.3736/jcim20120707},
  pmid    = {22805083},
  url     = {https://doi.org/10.3736/jcim20120707}
}

@article{kurz2012-21986341,
  author  = {Kurz, A. and Thöne-Otto, A. and Cramer, B. and Egert, S. and Frölich, L. and Gertz, H. J. and Kehl, V. and Wagenpfeil, S. and others},
  title   = {{CORDIAL: cognitive rehabilitation and cognitive-behavioral treatment for early dementia in Alzheimer disease: a multicenter, randomized, controlled trial}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2012},
  doi     = {10.1097/wad.0b013e318231e46e},
  pmid    = {21986341},
  url     = {https://doi.org/10.1097/wad.0b013e318231e46e}
}

@article{mori2012-22829268,
  author  = {Mori, E. and Ikeda, M. and Kosaka, K. and {Donepezil-DLB Study Investigators}},
  title   = {{Donepezil for dementia with Lewy bodies: a randomized, placebo-controlled trial}},
  journal = {Annals of neurology},
  year    = {2012},
  doi     = {10.1002/ana.23557},
  pmid    = {22829268},
  url     = {https://doi.org/10.1002/ana.23557}
}

@article{stryjer2012-22751086,
  author  = {Stryjer, R. and Ophir, D. and Bar, F. and Spivak, B. and Weizman, A. and Strous, R. D.},
  title   = {{Rivastigmine treatment for the prevention of electroconvulsive therapy-induced memory deficits in patients with schizophrenia}},
  journal = {Clinical neuropharmacology},
  year    = {2012},
  doi     = {10.1097/wnf.0b013e31825e7945},
  pmid    = {22751086},
  url     = {https://doi.org/10.1097/wnf.0b013e31825e7945}
}

@article{thakurathi2012-22730476,
  author  = {Thakurathi, Neelam and Henderson, David C.},
  title   = {{Atypical antipsychotics are associated with incident diabetes in older adults without schizophrenia or bipolar disorder}},
  journal = {Evidence-Based Mental Health},
  year    = {2012},
  doi     = {10.1136/ebmental-2012-100740},
  pmid    = {22730476},
  url     = {https://doi.org/10.1136/ebmental-2012-100740}
}

@article{molloy2013-22718435,
  author  = {Molloy, D. W. and Standish, T. I. and Zhou, Q. and Guyatt, G. and {DARAD Study Group}},
  title   = {{A multicenter, blinded, randomized, factorial controlled trial of doxycycline and rifampin for treatment of Alzheimer's disease: the DARAD trial}},
  journal = {International journal of geriatric psychiatry},
  year    = {2013},
  doi     = {10.1002/gps.3846},
  pmid    = {22718435},
  url     = {https://doi.org/10.1002/gps.3846}
}

@article{fields2012-21775876,
  author  = {Fields, C. and Drye, L. and Vaidya, V. and Lyketsos, C. and {ADAPT Research Group}},
  title   = {{Celecoxib or naproxen treatment does not benefit depressive symptoms in persons age 70 and older: findings from a randomized controlled trial}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2012},
  doi     = {10.1097/jgp.0b013e318227f4da},
  pmid    = {21775876},
  url     = {https://doi.org/10.1097/jgp.0b013e318227f4da}
}

@article{sun2012-25657666,
  author  = {Sun, Y. and Wang, G. and Pan, Z. and Chen, S.},
  title   = {{Systematic review of atorvastatin for the treatment of Alzheimer's disease}},
  journal = {Neural regeneration research},
  year    = {2012},
  doi     = {10.3969/j.issn.1673-5374.2012.17.010},
  pmid    = {25657666},
  url     = {https://doi.org/10.3969/j.issn.1673-5374.2012.17.010}
}

@article{jyvakorpi2012-22624652,
  author  = {Jyvakorpi, S. K. and Puranen, T. and Pitkala, K. H. and Suominen, M. H.},
  title   = {{Nutritional treatment of aged individuals with Alzheimer disease living at home with their spouses: study protocol for a randomized controlled trial}},
  journal = {Trials},
  year    = {2012},
  doi     = {10.1186/1745-6215-13-66},
  pmid    = {22624652},
  url     = {https://doi.org/10.1186/1745-6215-13-66}
}

@article{roberts2012-22498844,
  author  = {Roberts, J. S. and Chen, C. A. and Uhlmann, W. R. and Green, R. C.},
  title   = {{Effectiveness of a condensed protocol for disclosing APOE genotype and providing risk education for Alzheimer disease}},
  journal = {Genetics in medicine : official journal of the American College of Medical Genetics},
  year    = {2012},
  doi     = {10.1038/gim.2012.37},
  pmid    = {22498844},
  url     = {https://doi.org/10.1038/gim.2012.37}
}

@article{miao2012-22500712,
  author  = {Miao, Y. C. and Tian, J. Z. and Shi, J. and Mao, M.},
  title   = {{Effects of Chinese medicine for tonifying the kidney and resolving phlegm and blood stasis in treating patients with amnestic mild cognitive impairment: a randomized, double-blind and parallel-controlled trial}},
  journal = {Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine},
  year    = {2012},
  doi     = {10.3736/jcim20120407},
  pmid    = {22500712},
  url     = {https://doi.org/10.3736/jcim20120407}
}

@article{carrie2012-22499458,
  author  = {Carrié, I. and van Kan, G. A. and Gillette-Guyonnet, S. and Andrieu, S. and Dartigues, J. F. and Touchon, J. and Dantoine, T. and Rouaud, O. and others},
  title   = {{Recruitment strategies for preventive trials. The MAPT study (MultiDomain Alzheimer Preventive Trial)}},
  journal = {The journal of nutrition, health \& aging},
  year    = {2012},
  doi     = {10.1007/s12603-012-0046-8},
  pmid    = {22499458},
  url     = {https://doi.org/10.1007/s12603-012-0046-8}
}

@article{devanand2012-21407047,
  author  = {Devanand, D. P. and Mintzer, J. and Schultz, S. and Sultzer, D. and de la Pena, D. and Gupta, S. and Colon, S. and Schimming, C. and others},
  title   = {{The antipsychotic discontinuation in Alzheimer disease trial: clinical rationale and study design}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2012},
  doi     = {10.1097/jgp.0b013e3182110563},
  pmid    = {21407047},
  url     = {https://doi.org/10.1097/jgp.0b013e3182110563}
}

@article{desousa2012-21878804,
  author  = {de Sousa, O. L. and Amaral, T. F.},
  title   = {{Three-week nutritional supplementation effect on long-term nutritional status of patients with mild Alzheimer disease}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2012},
  doi     = {10.1097/wad.0b013e31822c5bb3},
  pmid    = {21878804},
  url     = {https://doi.org/10.1097/wad.0b013e31822c5bb3}
}

@article{jelcic2012-22460609,
  author  = {Jelcic, N. and Cagnin, A. and Meneghello, F. and Turolla, A. and Ermani, M. and Dam, M.},
  title   = {{Effects of lexical-semantic treatment on memory in early Alzheimer disease: an observer-blinded randomized controlled trial}},
  journal = {Neurorehabilitation and neural repair},
  year    = {2012},
  doi     = {10.1177/1545968312440146},
  pmid    = {22460609},
  url     = {https://doi.org/10.1177/1545968312440146}
}

@article{rolinski2012-22419314,
  author  = {Rolinski, M. and Fox, C. and Maidment, I. and McShane, R.},
  title   = {{Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2012},
  doi     = {10.1002/14651858.cd006504.pub2},
  pmid    = {22419314},
  url     = {https://doi.org/10.1002/14651858.cd006504.pub2}
}

@article{deane2012-22406537,
  author  = {Deane, R. and Singh, I. and Sagare, A. P. and Bell, R. D. and Ross, N. T. and LaRue, B. and Love, R. and Perry, S. and others},
  title   = {{A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease}},
  journal = {The Journal of clinical investigation},
  year    = {2012},
  doi     = {10.1172/jci58642},
  pmid    = {22406537},
  url     = {https://doi.org/10.1172/jci58642}
}

@article{bond2012-22541366,
  author  = {Bond, M. and Rogers, G. and Peters, J. and Anderson, R. and Hoyle, M. and Miners, A. and Moxham, T. and Davis, S. and others},
  title   = {{The effectiveness and cost-effectiveness of donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer's disease (review of Technology Appraisal No. 111): a systematic review and economic model}},
  journal = {Health technology assessment (Winchester, England)},
  year    = {2012},
  doi     = {10.3310/hta16210},
  pmid    = {22541366},
  url     = {https://doi.org/10.3310/hta16210}
}

@article{peters2011-22228829,
  author  = {Peters, M. E. and Vaidya, V. and Drye, L. T. and Rosenberg, P. B. and Martin, B. K. and Porsteinsson, A. P. and Frangakis, C. E. and Mintzer, J. and others},
  title   = {{Sertraline for the treatment of depression in Alzheimer disease: genetic influences}},
  journal = {Journal of geriatric psychiatry and neurology},
  year    = {2011},
  doi     = {10.1177/0891988711422527},
  pmid    = {22228829},
  url     = {https://doi.org/10.1177/0891988711422527}
}

@article{fang2012-22015470,
  author  = {Fang, F. and Chen, X. and Huang, T. and Lue, L. F. and Luddy, J. S. and Yan, S. S.},
  title   = {{Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model}},
  journal = {Biochimica et biophysica acta},
  year    = {2012},
  doi     = {10.1016/j.bbadis.2011.10.004},
  pmid    = {22015470},
  url     = {https://doi.org/10.1016/j.bbadis.2011.10.004}
}

@article{ostrowitzki2012-21987394,
  author  = {Ostrowitzki, S. and Deptula, D. and Thurfjell, L. and Barkhof, F. and Bohrmann, B. and Brooks, D. J. and Klunk, W. E. and Ashford, E. and others},
  title   = {{Mechanism of amyloid removal in patients with Alzheimer disease treated with gantenerumab}},
  journal = {Archives of neurology},
  year    = {2012},
  doi     = {10.1001/archneurol.2011.1538},
  pmid    = {21987394},
  url     = {https://doi.org/10.1001/archneurol.2011.1538}
}

@article{andersen2011-21970467,
  author  = {Andersen, F. and Viitanen, M. and Halvorsen, D. S. and Straume, B. and Engstad, T. A.},
  title   = {{Co-morbidity and drug treatment in Alzheimer's disease. A cross sectional study of participants in the dementia study in northern Norway}},
  journal = {BMC geriatrics},
  year    = {2011},
  doi     = {10.1186/1471-2318-11-58},
  pmid    = {21970467},
  url     = {https://doi.org/10.1186/1471-2318-11-58}
}

@article{williams2012-21982844,
  author  = {Williams, R. J. and Spencer, J. P.},
  title   = {{Flavonoids, cognition, and dementia: actions, mechanisms, and potential therapeutic utility for Alzheimer disease}},
  journal = {Free radical biology \& medicine},
  year    = {2012},
  doi     = {10.1016/j.freeradbiomed.2011.09.010},
  pmid    = {21982844},
  url     = {https://doi.org/10.1016/j.freeradbiomed.2011.09.010}
}

@article{salloway2011-21917766,
  author  = {Salloway, S. and Sperling, R. and Keren, R. and Porsteinsson, A. P. and van Dyck, C. H. and Tariot, P. N. and Gilman, S. and Arnold, D. and others},
  title   = {{A phase 2 randomized trial of ELND005, scyllo-inositol, in mild to moderate Alzheimer disease}},
  journal = {Neurology},
  year    = {2011},
  doi     = {10.1212/wnl.0b013e3182309fa5},
  pmid    = {21917766},
  url     = {https://doi.org/10.1212/wnl.0b013e3182309fa5}
}

@article{fleisher2011-21917762,
  author  = {Fleisher, A. S. and Truran, D. and Mai, J. T. and Langbaum, J. B. and Aisen, P. S. and Cummings, J. L. and Jack, C. R. and Weiner, M. W. and others},
  title   = {{Chronic divalproex sodium use and brain atrophy in Alzheimer disease}},
  journal = {Neurology},
  year    = {2011},
  doi     = {10.1212/wnl.0b013e318230a16c},
  pmid    = {21917762},
  url     = {https://doi.org/10.1212/wnl.0b013e318230a16c}
}

@article{craft2012-21911655,
  author  = {Craft, S. and Baker, L. D. and Montine, T. J. and Minoshima, S. and Watson, G. S. and Claxton, A. and Arbuckle, M. and Callaghan, M. and others},
  title   = {{Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clinical trial}},
  journal = {Archives of neurology},
  year    = {2012},
  doi     = {10.1001/archneurol.2011.233},
  pmid    = {21911655},
  url     = {https://doi.org/10.1001/archneurol.2011.233}
}

@article{chen2012-21901364,
  author  = {Chen, S. and Liu, A. R. and An, F. M. and Yao, W. B. and Gao, X. D.},
  title   = {{Amelioration of neurodegenerative changes in cellular and rat models of diabetes-related Alzheimer's disease by exendin-4}},
  journal = {Age (Dordrecht, Netherlands)},
  year    = {2012},
  doi     = {10.1007/s11357-011-9303-8},
  pmid    = {21901364},
  url     = {https://doi.org/10.1007/s11357-011-9303-8}
}

@article{mohamed2012-21939611,
  author  = {Mohamed, S. and Rosenheck, R. and Lyketsos, C. G. and Kaczynski, R. and Sultzer, D. L. and Schneider, L. S.},
  title   = {{Effect of second-generation antipsychotics on caregiver burden in Alzheimer's disease}},
  journal = {The Journal of clinical psychiatry},
  year    = {2012},
  doi     = {10.4088/jcp.10m06574},
  pmid    = {21939611},
  url     = {https://doi.org/10.4088/jcp.10m06574}
}

@article{maher2011-21954480,
  author  = {Maher, A. R. and Maglione, M. and Bagley, S. and Suttorp, M. and Hu, J. H. and Ewing, B. and Wang, Z. and Timmer, M. and others},
  title   = {{Efficacy and comparative effectiveness of atypical antipsychotic medications for off-label uses in adults: a systematic review and meta-analysis}},
  journal = {JAMA},
  year    = {2011},
  doi     = {10.1001/jama.2011.1360},
  pmid    = {21954480},
  url     = {https://doi.org/10.1001/jama.2011.1360}
}

@article{tariot2011-21810649,
  author  = {Tariot, P. N. and Schneider, L. S. and Cummings, J. and Thomas, R. G. and Raman, R. and Jakimovich, L. J. and Loy, R. and Bartocci, B. and others},
  title   = {{Chronic divalproex sodium to attenuate agitation and clinical progression of Alzheimer disease}},
  journal = {Archives of general psychiatry},
  year    = {2011},
  doi     = {10.1001/archgenpsychiatry.2011.72},
  pmid    = {21810649},
  url     = {https://doi.org/10.1001/archgenpsychiatry.2011.72}
}

@article{harrington2011-21592048,
  author  = {Harrington, C. and Sawchak, S. and Chiang, C. and Davies, J. and Donovan, C. and Saunders, A. M. and Irizarry, M. and Jeter, B. and others},
  title   = {{Rosiglitazone does not improve cognition or global function when used as adjunctive therapy to AChE inhibitors in mild-to-moderate Alzheimer's disease: two phase 3 studies}},
  journal = {Current Alzheimer research},
  year    = {2011},
  doi     = {10.2174/156720511796391935},
  pmid    = {21592048},
  url     = {https://doi.org/10.2174/156720511796391935}
}

@article{sano2011-21795660,
  author  = {Sano, M. and Bell, K. L. and Galasko, D. and Galvin, J. E. and Thomas, R. G. and van Dyck, C. H. and Aisen, P. S.},
  title   = {{A randomized, double-blind, placebo-controlled trial of simvastatin to treat Alzheimer disease}},
  journal = {Neurology},
  year    = {2011},
  doi     = {10.1212/wnl.0b013e318228bf11},
  pmid    = {21795660},
  url     = {https://doi.org/10.1212/wnl.0b013e318228bf11}
}

@article{banerjee2011-21764118,
  author  = {Banerjee, S. and Hellier, J. and Dewey, M. and Romeo, R. and Ballard, C. and Baldwin, R. and Bentham, P. and Fox, C. and others},
  title   = {{Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial}},
  journal = {Lancet (London, England)},
  year    = {2011},
  doi     = {10.1016/s0140-6736(11)60830-1},
  pmid    = {21764118},
  url     = {https://doi.org/10.1016/s0140-6736(11)60830-1}
}

@article{breitner2011-21784351,
  author  = {Breitner, J. C. and Baker, L. D. and Montine, T. J. and Meinert, C. L. and Lyketsos, C. G. and Ashe, K. H. and Brandt, J. and Craft, S. and others},
  title   = {{Extended results of the Alzheimer's disease anti-inflammatory prevention trial}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2011},
  doi     = {10.1016/j.jalz.2010.12.014},
  pmid    = {21784351},
  url     = {https://doi.org/10.1016/j.jalz.2010.12.014}
}

@article{sabbagh2011-21192237,
  author  = {Sabbagh, M. N. and Agro, A. and Bell, J. and Aisen, P. S. and Schweizer, E. and Galasko, D.},
  title   = {{PF-04494700, an oral inhibitor of receptor for advanced glycation end products (RAGE), in Alzheimer disease}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2011},
  doi     = {10.1097/wad.0b013e318204b550},
  pmid    = {21192237},
  url     = {https://doi.org/10.1097/wad.0b013e318204b550}
}

@article{leoutsakos2012-21560159,
  author  = {Leoutsakos, J. M. and Muthen, B. O. and Breitner, J. C. and Lyketsos, C. G. and {ADAPT Research Team}},
  title   = {{Effects of non-steroidal anti-inflammatory drug treatments on cognitive decline vary by phase of pre-clinical Alzheimer disease: findings from the randomized controlled Alzheimer's Disease Anti-inflammatory Prevention Trial}},
  journal = {International journal of geriatric psychiatry},
  year    = {2012},
  doi     = {10.1002/gps.2723},
  pmid    = {21560159},
  url     = {https://doi.org/10.1002/gps.2723}
}

@article{schneider2011-21482915,
  author  = {Schneider, L. S. and Dagerman, K. S. and Higgins, J. P. and McShane, R.},
  title   = {{Lack of evidence for the efficacy of memantine in mild Alzheimer disease}},
  journal = {Archives of neurology},
  year    = {2011},
  doi     = {10.1001/archneurol.2011.69},
  pmid    = {21482915},
  url     = {https://doi.org/10.1001/archneurol.2011.69}
}

@article{rafii2011-21502597,
  author  = {Rafii, M. S. and Walsh, S. and Little, J. T. and Behan, K. and Reynolds, B. and Ward, C. and Jin, S. and Thomas, R. and others},
  title   = {{A phase II trial of huperzine A in mild to moderate Alzheimer disease}},
  journal = {Neurology},
  year    = {2011},
  doi     = {10.1212/wnl.0b013e318216eb7b},
  pmid    = {21502597},
  url     = {https://doi.org/10.1212/wnl.0b013e318216eb7b}
}

@article{roach2011-21937893,
  author  = {Roach, K. E. and Tappen, R. M. and Kirk-Sanchez, N. and Williams, C. L. and Loewenstein, D.},
  title   = {{A randomized controlled trial of an activity specific exercise program for individuals with Alzheimer disease in long-term care settings}},
  journal = {Journal of geriatric physical therapy (2001)},
  year    = {2011},
  doi     = {10.1519/jpt.0b013e31820aab9c},
  pmid    = {21937893},
  url     = {https://doi.org/10.1519/jpt.0b013e31820aab9c}
}

@article{mcclean2011-21525299,
  author  = {McClean, P. L. and Parthsarathy, V. and Faivre, E. and Hölscher, C.},
  title   = {{The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2011},
  doi     = {10.1523/jneurosci.0529-11.2011},
  pmid    = {21525299},
  url     = {https://doi.org/10.1523/jneurosci.0529-11.2011}
}

@article{spiegel2011-21418632,
  author  = {Spiegel, R. and Berres, M. and Miserez, A. R. and Monsch, A. U. and {Alzheimer's Disease Neuroimaging Initiative}},
  title   = {{For debate: substituting placebo controls in long-term Alzheimer's prevention trials}},
  journal = {Alzheimer's research \& therapy},
  year    = {2011},
  doi     = {10.1186/alzrt68},
  pmid    = {21418632},
  url     = {https://doi.org/10.1186/alzrt68}
}

@article{bunch2011-21410581,
  author  = {Bunch, T. J. and Crandall, B. G. and Weiss, J. P. and May, H. T. and Bair, T. L. and Osborn, J. S. and Anderson, J. L. and Muhlestein, J. B. and others},
  title   = {{Patients treated with catheter ablation for atrial fibrillation have long-term rates of death, stroke, and dementia similar to patients without atrial fibrillation}},
  journal = {Journal of cardiovascular electrophysiology},
  year    = {2011},
  doi     = {10.1111/j.1540-8167.2011.02035.x},
  pmid    = {21410581},
  url     = {https://doi.org/10.1111/j.1540-8167.2011.02035.x}
}

@article{aisen2011-22291741,
  author  = {Aisen, P. S. and Gauthier, S. and Ferris, S. H. and Saumier, D. and Haine, D. and Garceau, D. and Duong, A. and Suhy, J. and others},
  title   = {{Tramiprosate in mild-to-moderate Alzheimer's disease - a randomized, double-blind, placebo-controlled, multi-centre study (the Alphase Study)}},
  journal = {Archives of medical science : AMS},
  year    = {2011},
  doi     = {10.5114/aoms.2011.20612},
  pmid    = {22291741},
  url     = {https://doi.org/10.5114/aoms.2011.20612}
}

@article{bentwich2011-21246222,
  author  = {Bentwich, J. and Dobronevsky, E. and Aichenbaum, S. and Shorer, R. and Peretz, R. and Khaigrekht, M. and Marton, R. G. and Rabey, J. M.},
  title   = {{Beneficial effect of repetitive transcranial magnetic stimulation combined with cognitive training for the treatment of Alzheimer's disease: a proof of concept study}},
  journal = {Journal of neural transmission (Vienna, Austria : 1996)},
  year    = {2011},
  doi     = {10.1007/s00702-010-0578-1},
  pmid    = {21246222},
  url     = {https://doi.org/10.1007/s00702-010-0578-1}
}

@article{kwok2011-21216507,
  author  = {Kwok, T. and Lee, J. and Law, C. B. and Pan, P. C. and Yung, C. Y. and Choi, K. C. and Lam, L. C.},
  title   = {{A randomized placebo controlled trial of homocysteine lowering to reduce cognitive decline in older demented people}},
  journal = {Clinical nutrition (Edinburgh, Scotland)},
  year    = {2011},
  doi     = {10.1016/j.clnu.2010.12.004},
  pmid    = {21216507},
  url     = {https://doi.org/10.1016/j.clnu.2010.12.004}
}

@article{stein2011-21694461,
  author  = {Stein, M. S. and Scherer, S. C. and Ladd, K. S. and Harrison, L. C.},
  title   = {{A randomized controlled trial of high-dose vitamin D2 followed by intranasal insulin in Alzheimer's disease}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2011},
  doi     = {10.3233/jad-2011-110149},
  pmid    = {21694461},
  url     = {https://doi.org/10.3233/jad-2011-110149}
}

@article{reynolds2011-21199965,
  author  = {Reynolds, C. F. and Butters, M. A. and Lopez, O. and Pollock, B. G. and Dew, M. A. and Mulsant, B. H. and Lenze, E. J. and Holm, M. and others},
  title   = {{Maintenance treatment of depression in old age: a randomized, double-blind, placebo-controlled evaluation of the efficacy and safety of donepezil combined with antidepressant pharmacotherapy}},
  journal = {Archives of general psychiatry},
  year    = {2011},
  doi     = {10.1001/archgenpsychiatry.2010.184},
  pmid    = {21199965},
  url     = {https://doi.org/10.1001/archgenpsychiatry.2010.184}
}

@article{sato2011-21778673,
  author  = {Sato, Y. and Honda, Y. and Umeno, K. and Hayashida, N. and Iwamoto, J. and Takeda, T. and Matsumoto, H.},
  title   = {{The prevention of hip fracture with menatetrenone and risedronate plus calcium supplementation in elderly patients with Alzheimer disease: a randomized controlled trial}},
  journal = {The Kurume medical journal},
  year    = {2011},
  doi     = {10.2739/kurumemedj.57.117},
  pmid    = {21778673},
  url     = {https://doi.org/10.2739/kurumemedj.57.117}
}

@article{schneider2011-21220675,
  author  = {Schneider, L. S. and Insel, P. S. and Weiner, M. W. and {Alzheimer's Disease Neuroimaging Initiative}},
  title   = {{Treatment with cholinesterase inhibitors and memantine of patients in the Alzheimer's Disease Neuroimaging Initiative}},
  journal = {Archives of neurology},
  year    = {2011},
  doi     = {10.1001/archneurol.2010.343},
  pmid    = {21220675},
  url     = {https://doi.org/10.1001/archneurol.2010.343}
}

@article{rubright2010-20808101,
  author  = {Rubright, J. and Sankar, P. and Casarett, D. J. and Gur, R. and Xie, S. X. and Karlawish, J.},
  title   = {{A memory and organizational aid improves Alzheimer disease research consent capacity: results of a randomized, controlled trial}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2010},
  doi     = {10.1097/jgp.0b013e3181dd1c3b},
  pmid    = {20808101},
  url     = {https://doi.org/10.1097/jgp.0b013e3181dd1c3b}
}

@article{quinn2010-21045096,
  author  = {Quinn, J. F. and Raman, R. and Thomas, R. G. and Yurko-Mauro, K. and Nelson, E. B. and Van Dyck, C. and Galvin, J. E. and Emond, J. and others},
  title   = {{Docosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: a randomized trial}},
  journal = {JAMA},
  year    = {2010},
  doi     = {10.1001/jama.2010.1510},
  pmid    = {21045096},
  url     = {https://doi.org/10.1001/jama.2010.1510}
}

@article{anderson2011-20980201,
  author  = {Anderson, C. and Teo, K. and Gao, P. and Arima, H. and Dans, A. and Unger, T. and Commerford, P. and Dyal, L. and others},
  title   = {{Renin-angiotensin system blockade and cognitive function in patients at high risk of cardiovascular disease: analysis of data from the ONTARGET and TRANSCEND studies}},
  journal = {The Lancet. Neurology},
  year    = {2011},
  doi     = {10.1016/s1474-4422(10)70250-7},
  pmid    = {20980201},
  url     = {https://doi.org/10.1016/s1474-4422(10)70250-7}
}

@article{clare2010-20808145,
  author  = {Clare, L. and Linden, D. E. and Woods, R. T. and Whitaker, R. and Evans, S. J. and Parkinson, C. H. and van Paasschen, J. and Nelis, S. M. and others},
  title   = {{Goal-oriented cognitive rehabilitation for people with early-stage Alzheimer disease: a single-blind randomized controlled trial of clinical efficacy}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2010},
  doi     = {10.1097/jgp.0b013e3181d5792a},
  pmid    = {20808145},
  url     = {https://doi.org/10.1097/jgp.0b013e3181d5792a}
}

@article{akhondzadeh2010-20831681,
  author  = {Akhondzadeh, S. and Sabet, M. S. and Harirchian, M. H. and Togha, M. and Cheraghmakani, H. and Razeghi, S. and SSh, Hejazi and Yousefi, M. H. and others},
  title   = {{Saffron in the treatment of patients with mild to moderate Alzheimer's disease: a 16-week, randomized and placebo-controlled trial}},
  journal = {Journal of clinical pharmacy and therapeutics},
  year    = {2010},
  doi     = {10.1111/j.1365-2710.2009.01133.x},
  pmid    = {20831681},
  url     = {https://doi.org/10.1111/j.1365-2710.2009.01133.x}
}

@article{maheredwards2011-20872778,
  author  = {Maher-Edwards, G. and Dixon, R. and Hunter, J. and Gold, M. and Hopton, G. and Jacobs, G. and Williams, P.},
  title   = {{SB-742457 and donepezil in Alzheimer disease: a randomized, placebo-controlled study}},
  journal = {International journal of geriatric psychiatry},
  year    = {2011},
  doi     = {10.1002/gps.2562},
  pmid    = {20872778},
  url     = {https://doi.org/10.1002/gps.2562}
}

@article{morillasruiz2010-20850133,
  author  = {Morillas-Ruiz, J. M. and Rubio-Perez, J. M. and Albaladejo, M. D. and Zafrilla, P. and Parra, S. and Vidal-Guevara, M. L.},
  title   = {{Effect of an antioxidant drink on homocysteine levels in Alzheimer's patients}},
  journal = {Journal of the neurological sciences},
  year    = {2010},
  doi     = {10.1016/j.jns.2010.08.050},
  pmid    = {20850133},
  url     = {https://doi.org/10.1016/j.jns.2010.08.050}
}

@article{alaama2011-20845391,
  author  = {Al-Aama, T. and Brymer, C. and Gutmanis, I. and Woolmore-Goodwin, S. M. and Esbaugh, J. and Dasgupta, M.},
  title   = {{Melatonin decreases delirium in elderly patients: a randomized, placebo-controlled trial}},
  journal = {International journal of geriatric psychiatry},
  year    = {2011},
  doi     = {10.1002/gps.2582},
  pmid    = {20845391},
  url     = {https://doi.org/10.1002/gps.2582}
}

@article{geldmacher2011-20837824,
  author  = {Geldmacher, D. S. and Fritsch, T. and McClendon, M. J. and Landreth, G.},
  title   = {{A randomized pilot clinical trial of the safety of pioglitazone in treatment of patients with Alzheimer disease}},
  journal = {Archives of neurology},
  year    = {2011},
  doi     = {10.1001/archneurol.2010.229},
  pmid    = {20837824},
  url     = {https://doi.org/10.1001/archneurol.2010.229}
}

@article{vandenberghe2010-20687209,
  author  = {Vandenberghe, R. and Van Laere, K. and Ivanoiu, A. and Salmon, E. and Bastin, C. and Triau, E. and Hasselbalch, S. and Law, I. and others},
  title   = {{18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: a phase 2 trial}},
  journal = {Annals of neurology},
  year    = {2010},
  doi     = {10.1002/ana.22068},
  pmid    = {20687209},
  url     = {https://doi.org/10.1002/ana.22068}
}

@article{figueiro2011-20739160,
  author  = {Figueiró, M. and Ilha, J. and Linck, V. M. and Herrmann, A. P. and Nardin, P. and Menezes, C. B. and Achaval, M. and Gonçalves, C. A. and others},
  title   = {{The Amazonian herbal Marapuama attenuates cognitive impairment and neuroglial degeneration in a mouse Alzheimer model}},
  journal = {Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year    = {2011},
  doi     = {10.1016/j.phymed.2010.07.013},
  pmid    = {20739160},
  url     = {https://doi.org/10.1016/j.phymed.2010.07.013}
}

@article{emre2010-20729148,
  author  = {Emre, M. and Tsolaki, M. and Bonuccelli, U. and Destée, A. and Tolosa, E. and Kutzelnigg, A. and Ceballos-Baumann, A. and Zdravkovic, S. and others},
  title   = {{Memantine for patients with Parkinson's disease dementia or dementia with Lewy bodies: a randomised, double-blind, placebo-controlled trial}},
  journal = {The Lancet. Neurology},
  year    = {2010},
  doi     = {10.1016/s1474-4422(10)70194-0},
  pmid    = {20729148},
  url     = {https://doi.org/10.1016/s1474-4422(10)70194-0}
}

@article{jacova2010-5ee8585a,
  author  = {Jacova, Claudia and Maclure, Malcolm and Hosick, David and Mattson, Ron and Hsiung, Ging‐Yuek Robin and Lee, Philip John and Rabheru, Kiran and Beattie, B. Lynn and others},
  title   = {{P3‐429: Response to cholinesterase inhibitor medication at first renewal in a Canadian provincial drug coverage initiative: the British Columbia Alzheimer's Drug Therapy Initiative (BC ADTI) experience}},
  journal = {Alzheimer s \& Dementia},
  year    = {2010},
  doi     = {10.1016/j.jalz.2010.05.1972},
  url     = {https://doi.org/10.1016/j.jalz.2010.05.1972}
}

@article{cummings2010-20502014,
  author  = {Cummings, J. L. and Ferris, S. H. and Farlow, M. R. and Olin, J. T. and Meng, X.},
  title   = {{Effects of rivastigmine transdermal patch and capsule on aspects of clinical global impression of change in Alzheimer's disease: a retrospective analysis}},
  journal = {Dementia and geriatric cognitive disorders},
  year    = {2010},
  doi     = {10.1159/000296073},
  pmid    = {20502014},
  url     = {https://doi.org/10.1159/000296073}
}

@article{roman2010-20395618,
  author  = {Román, G. C. and Salloway, S. and Black, S. E. and Royall, D. R. and Decarli, C. and Weiner, M. W. and Moline, M. and Kumar, D. and others},
  title   = {{Randomized, placebo-controlled, clinical trial of donepezil in vascular dementia: differential effects by hippocampal size}},
  journal = {Stroke},
  year    = {2010},
  doi     = {10.1161/strokeaha.109.570077},
  pmid    = {20395618},
  url     = {https://doi.org/10.1161/strokeaha.109.570077}
}

@article{black2010-20505438,
  author  = {Black, R. S. and Sperling, R. A. and Safirstein, B. and Motter, R. N. and Pallay, A. and Nichols, A. and Grundman, M.},
  title   = {{A single ascending dose study of bapineuzumab in patients with Alzheimer disease}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2010},
  doi     = {10.1097/wad.0b013e3181c53b00},
  pmid    = {20505438},
  url     = {https://doi.org/10.1097/wad.0b013e3181c53b00}
}

@article{feldman2010-20200346,
  author  = {Feldman, H. H. and Doody, R. S. and Kivipelto, M. and Sparks, D. L. and Waters, D. D. and Jones, R. W. and Schwam, E. and Schindler, R. and others},
  title   = {{Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease: LEADe}},
  journal = {Neurology},
  year    = {2010},
  doi     = {10.1212/wnl.0b013e3181d6476a},
  pmid    = {20200346},
  url     = {https://doi.org/10.1212/wnl.0b013e3181d6476a}
}

@article{rinne2010-20189881,
  author  = {Rinne, Juha O. and Brooks, David James and Rossor, Martin N. and Fox, Nick C. and Bullock, Roger Alan and Klunk, William E. and Mathis, Chester A. and Blennow, Kaj and Barakos, Jerome A. and Okello, Aren and de Liano, Sofia Rodriguez Martinez and Liu, Enchi and Koller, Martin and Gregg, Keith M. and Schenk, Dale and Black, Ronald S. and Grundman, Michael},
  title   = {{11C-PiB PET assessment of change in fibrillar amyloid-β load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study}},
  journal = {The Lancet Neurology},
  year    = {2010},
  doi     = {10.1016/s1474-4422(10)70043-0},
  pmid    = {20189881},
  url     = {https://doi.org/10.1016/s1474-4422(10)70043-0}
}

@article{kieburtz2010-20142523,
  author  = {Kieburtz, K. and McDermott, M. P. and Voss, T. S. and Corey-Bloom, J. and Deuel, L. M. and Dorsey, E. R. and Factor, S. and Geschwind, M. D. and others},
  title   = {{A randomized, placebo-controlled trial of latrepirdine in Huntington disease}},
  journal = {Archives of neurology},
  year    = {2010},
  doi     = {10.1001/archneurol.2009.334},
  pmid    = {20142523},
  url     = {https://doi.org/10.1001/archneurol.2009.334}
}

@article{mowla2010-20075646,
  author  = {Mowla, A. and Pani, A.},
  title   = {{Comparison of topiramate and risperidone for the treatment of behavioral disturbances of patients with Alzheimer disease: a double-blind, randomized clinical trial}},
  journal = {Journal of clinical psychopharmacology},
  year    = {2010},
  doi     = {10.1097/jcp.0b013e3181ca0c59},
  pmid    = {20075646},
  url     = {https://doi.org/10.1097/jcp.0b013e3181ca0c59}
}

@article{lavretsky2010-20104071,
  author  = {Lavretsky, H. and Siddarth, P. and Irwin, M. R.},
  title   = {{Improving depression and enhancing resilience in family dementia caregivers: a pilot randomized placebo-controlled trial of escitalopram}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2010},
  doi     = {10.1097/jgp.0b013e3181beab1e},
  pmid    = {20104071},
  url     = {https://doi.org/10.1097/jgp.0b013e3181beab1e}
}

@article{rosenberg2010-20087081,
  author  = {Rosenberg, P. B. and Drye, L. T. and Martin, B. K. and Frangakis, C. and Mintzer, J. E. and Weintraub, D. and Porsteinsson, A. P. and Schneider, L. S. and others},
  title   = {{Sertraline for the treatment of depression in Alzheimer disease}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2010},
  doi     = {10.1097/jgp.0b013e3181c796eb},
  pmid    = {20087081},
  url     = {https://doi.org/10.1097/jgp.0b013e3181c796eb}
}

@article{munoz2010-19951717,
  author  = {Munoz, L. and Ammit, A. J.},
  title   = {{Targeting p38 MAPK pathway for the treatment of Alzheimer's disease}},
  journal = {Neuropharmacology},
  year    = {2010},
  doi     = {10.1016/j.neuropharm.2009.11.010},
  pmid    = {19951717},
  url     = {https://doi.org/10.1016/j.neuropharm.2009.11.010}
}

@article{green2009-20009055,
  author  = {Green, R. C. and Schneider, L. S. and Amato, D. A. and Beelen, A. P. and Wilcock, G. and Swabb, E. A. and Zavitz, K. H. and {Tarenflurbil Phase 3 Study Group}},
  title   = {{Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: a randomized controlled trial}},
  journal = {JAMA},
  year    = {2009},
  doi     = {10.1001/jama.2009.1866},
  pmid    = {20009055},
  url     = {https://doi.org/10.1001/jama.2009.1866}
}

@article{salloway2009-19923550,
  author  = {Salloway, S. and Sperling, R. and Gilman, S. and Fox, N. C. and Blennow, K. and Raskind, M. and Sabbagh, M. and Honig, L. S. and others},
  title   = {{A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease}},
  journal = {Neurology},
  year    = {2009},
  doi     = {10.1212/wnl.0b013e3181c67808},
  pmid    = {19923550},
  url     = {https://doi.org/10.1212/wnl.0b013e3181c67808}
}

@article{sato2011-19923038,
  author  = {Sato, T. and Hanyu, H. and Hirao, K. and Kanetaka, H. and Sakurai, H. and Iwamoto, T.},
  title   = {{Efficacy of PPAR-γ agonist pioglitazone in mild Alzheimer disease}},
  journal = {Neurobiology of aging},
  year    = {2011},
  doi     = {10.1016/j.neurobiolaging.2009.10.009},
  pmid    = {19923038},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2009.10.009}
}

@article{modrego2010-19874395,
  author  = {Modrego, P. J. and Fayed, N. and Errea, J. M. and Rios, C. and Pina, M. A. and Sarasa, M.},
  title   = {{Memantine versus donepezil in mild to moderate Alzheimer's disease: a randomized trial with magnetic resonance spectroscopy}},
  journal = {European journal of neurology},
  year    = {2010},
  doi     = {10.1111/j.1468-1331.2009.02816.x},
  pmid    = {19874395},
  url     = {https://doi.org/10.1111/j.1468-1331.2009.02816.x}
}

@article{rountree2009-19845950,
  author  = {Rountree, S. D. and Chan, W. and Pavlik, V. N. and Darby, E. J. and Siddiqui, S. and Doody, R. S.},
  title   = {{Persistent treatment with cholinesterase inhibitors and/or memantine slows clinical progression of Alzheimer disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2009},
  doi     = {10.1186/alzrt7},
  pmid    = {19845950},
  url     = {https://doi.org/10.1186/alzrt7}
}

@article{jones2009-19561444,
  author  = {Jones, R. W. and Schwam, E. and Wilkinson, D. and Waldemar, G. and Feldman, H. H. and Zhang, R. and Albert, K. and Schindler, R.},
  title   = {{Rates of cognitive change in Alzheimer disease: observations across a decade of placebo-controlled clinical trials with donepezil}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2009},
  doi     = {10.1097/wad.0b013e31819cd4be},
  pmid    = {19561444},
  url     = {https://doi.org/10.1097/wad.0b013e31819cd4be}
}

@article{mohs2009-19700948,
  author  = {Mohs, R. C. and Shiovitz, T. M. and Tariot, P. N. and Porsteinsson, A. P. and Baker, K. D. and Feldman, P. D.},
  title   = {{Atomoxetine augmentation of cholinesterase inhibitor therapy in patients with Alzheimer disease: 6-month, randomized, double-blind, placebo-controlled, parallel-trial study}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2009},
  doi     = {10.1097/jgp.0b013e3181aad585},
  pmid    = {19700948},
  url     = {https://doi.org/10.1097/jgp.0b013e3181aad585}
}

@article{ballard2009-19700946,
  author  = {Ballard, C. and Brown, R. and Fossey, J. and Douglas, S. and Bradley, P. and Hancock, J. and James, I. A. and Juszczak, E. and others},
  title   = {{Brief psychosocial therapy for the treatment of agitation in Alzheimer disease (the CALM-AD trial)}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2009},
  doi     = {10.1097/jgp.0b013e3181b0f8c0},
  pmid    = {19700946},
  url     = {https://doi.org/10.1097/jgp.0b013e3181b0f8c0}
}

@article{shega2009-19622011,
  author  = {Shega, J. W. and Ellner, L. and Lau, D. T. and Maxwell, T. L.},
  title   = {{Cholinesterase inhibitor and N-methyl-D-aspartic acid receptor antagonist use in older adults with end-stage dementia: a survey of hospice medical directors}},
  journal = {Journal of palliative medicine},
  year    = {2009},
  doi     = {10.1089/jpm.2009.0059},
  pmid    = {19622011},
  url     = {https://doi.org/10.1089/jpm.2009.0059}
}

@article{pilotto2009-19738170,
  author  = {Pilotto, A. and Franceschi, M. and D'Onofrio, G. and Bizzarro, A. and Mangialasche, F. and Cascavilla, L. and Paris, F. and Matera, M. G. and others},
  title   = {{Effect of a CYP2D6 polymorphism on the efficacy of donepezil in patients with Alzheimer disease}},
  journal = {Neurology},
  year    = {2009},
  doi     = {10.1212/wnl.0b013e3181b6bbe3},
  pmid    = {19738170},
  url     = {https://doi.org/10.1212/wnl.0b013e3181b6bbe3}
}

@article{brodaty2009-19705519,
  author  = {Brodaty, H. and Mittelman, M. and Gibson, L. and Seeher, K. and Burns, A.},
  title   = {{The effects of counseling spouse caregivers of people with Alzheimer disease taking donepezil and of country of residence on rates of admission to nursing homes and mortality}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2009},
  doi     = {10.1097/jgp.0b013e3181a65187},
  pmid    = {19705519},
  url     = {https://doi.org/10.1097/jgp.0b013e3181a65187}
}

@article{jung2009-19652386,
  author  = {Jung, H. A. and Min, B. S. and Yokozawa, T. and Lee, J. H. and Kim, Y. S. and Choi, J. S.},
  title   = {{Anti-Alzheimer and antioxidant activities of Coptidis Rhizoma alkaloids}},
  journal = {Biological \& pharmaceutical bulletin},
  year    = {2009},
  doi     = {10.1248/bpb.32.1433},
  pmid    = {19652386},
  url     = {https://doi.org/10.1248/bpb.32.1433}
}

@article{almaraz2009-19590387,
  author  = {Almaraz, A. C. and Driver-Dunckley, E. D. and Woodruff, B. K. and Wellik, K. E. and Caselli, R. J. and Demaerschalk, B. M. and Adler, C. H. and Caviness, J. N. and others},
  title   = {{Efficacy of rivastigmine for cognitive symptoms in Parkinson disease with dementia}},
  journal = {The neurologist},
  year    = {2009},
  doi     = {10.1097/nrl.0b013e3181a968df},
  pmid    = {19590387},
  url     = {https://doi.org/10.1097/nrl.0b013e3181a968df}
}

@article{fonseca2009-19561098,
  author  = {Fonseca, M. I. and Ager, R. R. and Chu, S. H. and Yazan, O. and Sanderson, S. D. and LaFerla, F. M. and Taylor, S. M. and Woodruff, T. M. and others},
  title   = {{Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease}},
  journal = {Journal of immunology (Baltimore, Md. : 1950)},
  year    = {2009},
  doi     = {10.4049/jimmunol.0901005},
  pmid    = {19561098},
  url     = {https://doi.org/10.4049/jimmunol.0901005}
}

@article{lu2009-19528519,
  author  = {Lu, P. H. and Edland, S. D. and Teng, E. and Tingus, K. and Petersen, R. C. and Cummings, J. L. and {Alzheimer's Disease Cooperative Study Group}},
  title   = {{Donepezil delays progression to AD in MCI subjects with depressive symptoms}},
  journal = {Neurology},
  year    = {2009},
  doi     = {10.1212/wnl.0b013e3181aa52d3},
  pmid    = {19528519},
  url     = {https://doi.org/10.1212/wnl.0b013e3181aa52d3}
}

@article{gauthier2009-19536424,
  author  = {Gauthier, S. and Aisen, P. S. and Ferris, S. H. and Saumier, D. and Duong, A. and Haine, D. and Garceau, D. and Suhy, J. and others},
  title   = {{Effect of tramiprosate in patients with mild-to-moderate Alzheimer's disease: exploratory analyses of the MRI sub-group of the Alphase study}},
  journal = {The journal of nutrition, health \& aging},
  year    = {2009},
  doi     = {10.1007/s12603-009-0106-x},
  pmid    = {19536424},
  url     = {https://doi.org/10.1007/s12603-009-0106-x}
}

@article{krishnan2009-19370677,
  author  = {Krishnan, S. and Cairns, R. and Howard, R.},
  title   = {{Cannabinoids for the treatment of dementia}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2009},
  doi     = {10.1002/14651858.cd007204.pub2},
  pmid    = {19370677},
  url     = {https://doi.org/10.1002/14651858.cd007204.pub2}
}

@article{pasqualetti2009-19448381,
  author  = {Pasqualetti, P. and Bonomini, C. and Dal Forno, G. and Paulon, L. and Sinforiani, E. and Marra, C. and Zanetti, O. and Rossini, P. M.},
  title   = {{A randomized controlled study on effects of ibuprofen on cognitive progression of Alzheimer's disease}},
  journal = {Aging clinical and experimental research},
  year    = {2009},
  doi     = {10.1007/bf03325217},
  pmid    = {19448381},
  url     = {https://doi.org/10.1007/bf03325217}
}

@article{gilletteguyonnet2009-19328438,
  author  = {Gillette-Guyonnet, S. and Andrieu, S. and Dantoine, T. and Dartigues, J. F. and Touchon, J. and Vellas, B. and {MAPT Study Group}},
  title   = {{Commentary on "A roadmap for the prevention of dementia II. Leon Thal Symposium 2008." The Multidomain Alzheimer Preventive Trial (MAPT): a new approach to the prevention of Alzheimer's disease}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2009},
  doi     = {10.1016/j.jalz.2009.01.008},
  pmid    = {19328438},
  url     = {https://doi.org/10.1016/j.jalz.2009.01.008}
}

@article{kountouras2009-19240960,
  author  = {Kountouras, J. and Boziki, M. and Gavalas, E. and Zavos, C. and Grigoriadis, N. and Deretzi, G. and Tzilves, D. and Katsinelos, P. and others},
  title   = {{Eradication of Helicobacter pylori may be beneficial in the management of Alzheimer's disease}},
  journal = {Journal of neurology},
  year    = {2009},
  doi     = {10.1007/s00415-009-5011-z},
  pmid    = {19240960},
  url     = {https://doi.org/10.1007/s00415-009-5011-z}
}

@article{gehrman2009-19155748,
  author  = {Gehrman, P. R. and Connor, D. J. and Martin, J. L. and Shochat, T. and Corey-Bloom, J. and Ancoli-Israel, S.},
  title   = {{Melatonin fails to improve sleep or agitation in double-blind randomized placebo-controlled trial of institutionalized patients with Alzheimer disease}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2009},
  doi     = {10.1097/jgp.0b013e318187de18},
  pmid    = {19155748},
  url     = {https://doi.org/10.1097/jgp.0b013e318187de18}
}

@article{doody2009-19176895,
  author  = {Doody, R. S. and Ferris, S. H. and Salloway, S. and Sun, Y. and Goldman, R. and Watkins, W. E. and Xu, Y. and Murthy, A. K.},
  title   = {{Donepezil treatment of patients with MCI: a 48-week randomized, placebo-controlled trial}},
  journal = {Neurology},
  year    = {2009},
  doi     = {10.1212/01.wnl.0000344650.95823.03},
  pmid    = {19176895},
  url     = {https://doi.org/10.1212/01.wnl.0000344650.95823.03}
}

@article{viswanathan2009-19153374,
  author  = {Viswanathan, A. and Raj, S. and Greenberg, S. M. and Stampfer, M. and Campbell, S. and Hyman, B. T. and Irizarry, M. C.},
  title   = {{Plasma Abeta, homocysteine, and cognition: the Vitamin Intervention for Stroke Prevention (VISP) trial}},
  journal = {Neurology},
  year    = {2009},
  doi     = {10.1212/01.wnl.0000339486.63862.db},
  pmid    = {19153374},
  url     = {https://doi.org/10.1212/01.wnl.0000339486.63862.db}
}

@article{mizukami2009-19079814,
  author  = {Mizukami, K. and Asada, T. and Kinoshita, T. and Tanaka, K. and Sonohara, K. and Nakai, R. and Yamaguchi, K. and Hanyu, H. and others},
  title   = {{A randomized cross-over study of a traditional Japanese medicine (kampo), yokukansan, in the treatment of the behavioural and psychological symptoms of dementia}},
  journal = {The international journal of neuropsychopharmacology},
  year    = {2009},
  doi     = {10.1017/s146114570800970x},
  pmid    = {19079814},
  url     = {https://doi.org/10.1017/s146114570800970x}
}

@article{mittelman2008-18978250,
  author  = {Mittelman, M. S. and Brodaty, H. and Wallen, A. S. and Burns, A.},
  title   = {{A three-country randomized controlled trial of a psychosocial intervention for caregivers combined with pharmacological treatment for patients with Alzheimer disease: effects on caregiver depression}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2008},
  doi     = {10.1097/jgp.0b013e3181898095},
  pmid    = {18978250},
  url     = {https://doi.org/10.1097/jgp.0b013e3181898095}
}

@article{dekosky2008-19017911,
  author  = {DeKosky, S. T. and Williamson, J. D. and Fitzpatrick, A. L. and Kronmal, R. A. and Ives, D. G. and Saxton, J. A. and Lopez, O. L. and Burke, G. and others},
  title   = {{Ginkgo biloba for prevention of dementia: a randomized controlled trial}},
  journal = {JAMA},
  year    = {2008},
  doi     = {10.1001/jama.2008.683},
  pmid    = {19017911},
  url     = {https://doi.org/10.1001/jama.2008.683}
}

@article{sevigny2008-19015485,
  author  = {Sevigny, J. J. and Ryan, J. M. and van Dyck, C. H. and Peng, Y. and Lines, C. R. and Nessly, M. L. and {MK-677 Protocol 30 Study Group}},
  title   = {{Growth hormone secretagogue MK-677: no clinical effect on AD progression in a randomized trial}},
  journal = {Neurology},
  year    = {2008},
  doi     = {10.1212/01.wnl.0000335163.88054.e7},
  pmid    = {19015485},
  url     = {https://doi.org/10.1212/01.wnl.0000335163.88054.e7}
}

@article{schaeffer2009-18853146,
  author  = {Schaeffer, E. L. and Forlenza, O. V. and Gattaz, W. F.},
  title   = {{Phospholipase A2 activation as a therapeutic approach for cognitive enhancement in early-stage Alzheimer disease}},
  journal = {Psychopharmacology},
  year    = {2009},
  doi     = {10.1007/s00213-008-1351-0},
  pmid    = {18853146},
  url     = {https://doi.org/10.1007/s00213-008-1351-0}
}

@article{aisen2008-18854539,
  author  = {Aisen, P. S. and Schneider, L. S. and Sano, M. and Diaz-Arrastia, R. and van Dyck, C. H. and Weiner, M. F. and Bottiglieri, T. and Jin, S. and others},
  title   = {{High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial}},
  journal = {JAMA},
  year    = {2008},
  doi     = {10.1001/jama.300.15.1774},
  pmid    = {18854539},
  url     = {https://doi.org/10.1001/jama.300.15.1774}
}

@article{ancoliisrael2008-18795985,
  author  = {Ancoli-Israel, S. and Palmer, B. W. and Cooke, JR. and Corey-Bloom, J. and Fiorentino, L. and Natarajan, L. and Liu, L. and Ayalon, L. and others},
  title   = {{Cognitive effects of treating obstructive sleep apnea in Alzheimer's disease: a randomized controlled study}},
  journal = {Journal of the American Geriatrics Society},
  year    = {2008},
  doi     = {10.1111/j.1532-5415.2008.01934.x},
  pmid    = {18795985},
  url     = {https://doi.org/10.1111/j.1532-5415.2008.01934.x}
}

@article{diener2008-18757238,
  author  = {Diener, H. C. and Sacco, R. L. and Yusuf, S. and Cotton, D. and Ounpuu, S. and Lawton, W. A. and Palesch, Y. and Martin, R. H. and others},
  title   = {{Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial: a double-blind, active and placebo-controlled study}},
  journal = {The Lancet. Neurology},
  year    = {2008},
  doi     = {10.1016/s1474-4422(08)70198-4},
  pmid    = {18757238},
  url     = {https://doi.org/10.1016/s1474-4422(08)70198-4}
}

@article{heo2008-18684311,
  author  = {Heo, J. H. and Lee, S. T. and Chu, K. and Oh, M. J. and Park, H. J. and Shim, J. Y. and Kim, M.},
  title   = {{An open-label trial of Korean red ginseng as an adjuvant treatment for cognitive impairment in patients with Alzheimer's disease}},
  journal = {European journal of neurology},
  year    = {2008},
  doi     = {10.1111/j.1468-1331.2008.02157.x},
  pmid    = {18684311},
  url     = {https://doi.org/10.1111/j.1468-1331.2008.02157.x}
}

@article{fleisher2008-18695053,
  author  = {Fleisher, A. S. and Raman, R. and Siemers, E. R. and Becerra, L. and Clark, C. M. and Dean, R. A. and Farlow, M. R. and Galvin, J. E. and others},
  title   = {{Phase 2 safety trial targeting amyloid beta production with a gamma-secretase inhibitor in Alzheimer disease}},
  journal = {Archives of neurology},
  year    = {2008},
  doi     = {10.1001/archneur.65.8.1031},
  pmid    = {18695053},
  url     = {https://doi.org/10.1001/archneur.65.8.1031}
}

@article{ballard2008-18674411,
  author  = {Ballard, C. and Sauter, M. and Scheltens, P. and He, Y. and Barkhof, F. and van Straaten, E. C. and van der Flier, W. M. and Hsu, C. and others},
  title   = {{Efficacy, safety and tolerability of rivastigmine capsules in patients with probable vascular dementia: the VantagE study}},
  journal = {Current medical research and opinion},
  year    = {2008},
  doi     = {10.1185/03007990802328142},
  pmid    = {18674411},
  url     = {https://doi.org/10.1185/03007990802328142}
}

@article{maczurek2008-18655815,
  author  = {Maczurek, A. and Hager, K. and Kenklies, M. and Sharman, M. and Martins, R. and Engel, J. and Carlson, D. A. and Münch, G.},
  title   = {{Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease}},
  journal = {Advanced drug delivery reviews},
  year    = {2008},
  doi     = {10.1016/j.addr.2008.04.015},
  pmid    = {18655815},
  url     = {https://doi.org/10.1016/j.addr.2008.04.015}
}

@article{streim2008-18591574,
  author  = {Streim, J. E. and Porsteinsson, A. P. and Breder, C. D. and Swanink, R. and Marcus, R. and McQuade, R. and Carson, W. H.},
  title   = {{A randomized, double-blind, placebo-controlled study of aripiprazole for the treatment of psychosis in nursing home patients with Alzheimer disease}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2008},
  doi     = {10.1097/jgp.0b013e318165db77},
  pmid    = {18591574},
  url     = {https://doi.org/10.1097/jgp.0b013e318165db77}
}

@article{holmes2008-18640458,
  author  = {Holmes, C. and Boche, D. and Wilkinson, D. and Yadegarfar, G. and Hopkins, V. and Bayer, A. and Jones, R. W. and Bullock, R. and others},
  title   = {{Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial}},
  journal = {Lancet (London, England)},
  year    = {2008},
  doi     = {10.1016/s0140-6736(08)61075-2},
  pmid    = {18640458},
  url     = {https://doi.org/10.1016/s0140-6736(08)61075-2}
}

@article{gallagher2008-18573187,
  author  = {Gallagher, A. M. and Rietbrock, S. and Plumb, J. and van Staa, T. P.},
  title   = {{Initiation and persistence of warfarin or aspirin in patients with chronic atrial fibrillation in general practice: do the appropriate patients receive stroke prophylaxis?}},
  journal = {Journal of thrombosis and haemostasis : JTH},
  year    = {2008},
  doi     = {10.1111/j.1538-7836.2008.03059.x},
  pmid    = {18573187},
  url     = {https://doi.org/10.1111/j.1538-7836.2008.03059.x}
}

@article{fitzgerald2008-18541979,
  author  = {FitzGerald, D. B. and Crucian, G. P. and Mielke, J. B. and Shenal, B. V. and Burks, D. and Womack, K. B. and Ghacibeh, G. and Drago, V. and others},
  title   = {{Effects of donepezil on verbal memory after semantic processing in healthy older adults}},
  journal = {Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology},
  year    = {2008},
  doi     = {10.1097/wnn.0b013e3181799df1},
  pmid    = {18541979},
  url     = {https://doi.org/10.1097/wnn.0b013e3181799df1}
}

@article{herrmann2008-18480686,
  author  = {Herrmann, N. and Rothenburg, L. S. and Black, S. E. and Ryan, M. and Liu, B. A. and Busto, U. E. and Lanctôt, K. L.},
  title   = {{Methylphenidate for the treatment of apathy in Alzheimer disease: prediction of response using dextroamphetamine challenge}},
  journal = {Journal of clinical psychopharmacology},
  year    = {2008},
  doi     = {10.1097/jcp.0b013e318172b479},
  pmid    = {18480686},
  url     = {https://doi.org/10.1097/jcp.0b013e318172b479}
}

@article{study2008-18474729,
  author  = {{ADAPT Research Group} and Martin, B. K. and Szekely, C. and Brandt, J. and Piantadosi, S. and Breitner, J. C. and Craft, S. and Evans, D. and others},
  title   = {{Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): results of a randomized, controlled trial of naproxen and celecoxib}},
  journal = {Archives of neurology},
  year    = {2008},
  doi     = {10.1001/archneur.2008.65.7.nct70006},
  pmid    = {18474729},
  url     = {https://doi.org/10.1001/archneur.2008.65.7.nct70006}
}

@article{wilcock2008-18450517,
  author  = {Wilcock, G. K. and Black, S. E. and Hendrix, S. B. and Zavitz, K. H. and Swabb, E. A. and Laughlin, M. A. and {Tarenflurbil Phase II Study investigators}},
  title   = {{Efficacy and safety of tarenflurbil in mild to moderate Alzheimer's disease: a randomised phase II trial}},
  journal = {The Lancet. Neurology},
  year    = {2008},
  doi     = {10.1016/s1474-4422(08)70090-5},
  pmid    = {18450517},
  url     = {https://doi.org/10.1016/s1474-4422(08)70090-5}
}

@article{raina2008-18316756,
  author  = {Raina, P. and Santaguida, P. and Ismaila, A. and Patterson, C. and Cowan, D. and Levine, M. and Booker, L. and Oremus, M.},
  title   = {{Effectiveness of cholinesterase inhibitors and memantine for treating dementia: evidence review for a clinical practice guideline}},
  journal = {Annals of internal medicine},
  year    = {2008},
  doi     = {10.7326/0003-4819-148-5-200803040-00009},
  pmid    = {18316756},
  url     = {https://doi.org/10.7326/0003-4819-148-5-200803040-00009}
}

@article{karlawish2008-18310554,
  author  = {Karlawish, J. and Kim, S. Y. and Knopman, D. and van Dyck, C. H. and James, B. D. and Marson, D.},
  title   = {{The views of Alzheimer disease patients and their study partners on proxy consent for clinical trial enrollment}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2008},
  doi     = {10.1097/jgp.0b013e318162992d},
  pmid    = {18310554},
  url     = {https://doi.org/10.1097/jgp.0b013e318162992d}
}

@article{dichgans2008-18296124,
  author  = {Dichgans, M. and Markus, H. S. and Salloway, S. and Verkkoniemi, A. and Moline, M. and Wang, Q. and Posner, H. and Chabriat, H. S.},
  title   = {{Donepezil in patients with subcortical vascular cognitive impairment: a randomised double-blind trial in CADASIL}},
  journal = {The Lancet. Neurology},
  year    = {2008},
  doi     = {10.1016/s1474-4422(08)70046-2},
  pmid    = {18296124},
  url     = {https://doi.org/10.1016/s1474-4422(08)70046-2}
}

@article{porsteinsson2008-18288936,
  author  = {Porsteinsson, A. P. and Grossberg, G. T. and Mintzer, J. and Olin, J. T. and {Memantine MEM-MD-12 Study Group}},
  title   = {{Memantine treatment in patients with mild to moderate Alzheimer's disease already receiving a cholinesterase inhibitor: a randomized, double-blind, placebo-controlled trial}},
  journal = {Current Alzheimer research},
  year    = {2008},
  doi     = {10.2174/156720508783884576},
  pmid    = {18288936},
  url     = {https://doi.org/10.2174/156720508783884576}
}

@article{freundlevi2008-17582225,
  author  = {Freund-Levi, Y. and Basun, H. and Cederholm, T. and Faxén-Irving, G. and Garlind, A. and Grut, M. and Vedin, I. and Palmblad, J. and others},
  title   = {{Omega-3 supplementation in mild to moderate Alzheimer's disease: effects on neuropsychiatric symptoms}},
  journal = {International journal of geriatric psychiatry},
  year    = {2008},
  doi     = {10.1002/gps.1857},
  pmid    = {17582225},
  url     = {https://doi.org/10.1002/gps.1857}
}

@article{dejong2008-18213383,
  author  = {de Jong, D. and Jansen, R. and Hoefnagels, W. and Jellesma-Eggenkamp, M. and Verbeek, M. and Borm, G. and Kremer, B.},
  title   = {{No effect of one-year treatment with indomethacin on Alzheimer's disease progression: a randomized controlled trial}},
  journal = {PloS one},
  year    = {2008},
  doi     = {10.1371/journal.pone.0001475},
  pmid    = {18213383},
  url     = {https://doi.org/10.1371/journal.pone.0001475}
}

@article{moraes2008-18198262,
  author  = {Moraes, W. and Poyares, D. and Sukys-Claudino, L. and Guilleminault, C. and Tufik, S.},
  title   = {{Donepezil improves obstructive sleep apnea in Alzheimer disease: a double-blind, placebo-controlled study}},
  journal = {Chest},
  year    = {2008},
  doi     = {10.1378/chest.07-1446},
  pmid    = {18198262},
  url     = {https://doi.org/10.1378/chest.07-1446}
}

@article{gomezisla2008-18317243,
  author  = {Gómez-Isla, T. and Blesa, R. and Boada, M. and Clarimón, J. and Del Ser, T. and Domenech, G. and Ferro, J. M. and Gómez-Ansón, B. and others},
  title   = {{A randomized, double-blind, placebo controlled-trial of triflusal in mild cognitive impairment: the TRIMCI study}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2008},
  doi     = {10.1097/wad.0b013e3181611024},
  pmid    = {18317243},
  url     = {https://doi.org/10.1097/wad.0b013e3181611024}
}

@article{pae2008-18399707,
  author  = {Pae, C. U. and Serretti, A. and Patkar, A. A. and Masand, P. S.},
  title   = {{Aripiprazole in the treatment of depressive and anxiety disorders: a review of current evidence}},
  journal = {CNS drugs},
  year    = {2008},
  doi     = {10.2165/00023210-200822050-00002},
  pmid    = {18399707},
  url     = {https://doi.org/10.2165/00023210-200822050-00002}
}

@article{study2008-18068522,
  author  = {{AD2000 Collaborative Group} and Bentham, P. and Gray, R. and Sellwood, E. and Hills, R. and Crome, P. and Raftery, J.},
  title   = {{Aspirin in Alzheimer's disease (AD2000): a randomised open-label trial}},
  journal = {The Lancet. Neurology},
  year    = {2008},
  doi     = {10.1016/s1474-4422(07)70293-4},
  pmid    = {18068522},
  url     = {https://doi.org/10.1016/s1474-4422(07)70293-4}
}

@article{mandel2008-19040558,
  author  = {Mandel, S. A. and Amit, T. and Weinreb, O. and Reznichenko, L. and Youdim, M. B.},
  title   = {{Simultaneous manipulation of multiple brain targets by green tea catechins: a potential neuroprotective strategy for Alzheimer and Parkinson diseases}},
  journal = {CNS neuroscience \& therapeutics},
  year    = {2008},
  doi     = {10.1111/j.1755-5949.2008.00060.x},
  pmid    = {19040558},
  url     = {https://doi.org/10.1111/j.1755-5949.2008.00060.x}
}

@article{mishra2008-19966973,
  author  = {Mishra, S. and Palanivelu, K.},
  title   = {{The effect of curcumin (turmeric) on Alzheimer's disease: An overview}},
  journal = {Annals of Indian Academy of Neurology},
  year    = {2008},
  doi     = {10.4103/0972-2327.40220},
  pmid    = {19966973},
  url     = {https://doi.org/10.4103/0972-2327.40220}
}

@article{koepsell2007-17984455,
  author  = {Koepsell, T. D. and Chi, Y. Y. and Zhou, X. H. and Lee, W. W. and Ramos, E. M. and Kukull, W. A.},
  title   = {{An alternative method for estimating efficacy of the AN1792 vaccine for Alzheimer disease}},
  journal = {Neurology},
  year    = {2007},
  doi     = {10.1212/01.wnl.0000278226.96003.f8},
  pmid    = {17984455},
  url     = {https://doi.org/10.1212/01.wnl.0000278226.96003.f8}
}

@article{rosenheck2007-17984395,
  author  = {Rosenheck, R. A. and Leslie, D. L. and Sindelar, J. L. and Miller, E. A. and Tariot, P. N. and Dagerman, K. S. and Davis, S. M. and Lebowitz, B. D. and others},
  title   = {{Cost-benefit analysis of second-generation antipsychotics and placebo in a randomized trial of the treatment of psychosis and aggression in Alzheimer disease}},
  journal = {Archives of general psychiatry},
  year    = {2007},
  doi     = {10.1001/archpsyc.64.11.1259},
  pmid    = {17984395},
  url     = {https://doi.org/10.1001/archpsyc.64.11.1259}
}

@article{tinklenberg2007-17974866,
  author  = {Tinklenberg, JR. and Kraemer, H. C. and Yaffe, K. and Ross, L. and Sheikh, J. and Ashford, J. W. and Yesavage, J. A. and Taylor, J. L.},
  title   = {{Donepezil treatment and Alzheimer disease: can the results of randomized clinical trials be applied to Alzheimer disease patients in clinical practice?}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2007},
  doi     = {10.1097/jgp.0b013e3180986138},
  pmid    = {17974866},
  url     = {https://doi.org/10.1097/jgp.0b013e3180986138}
}

@article{piazzi2008-17998161,
  author  = {Piazzi, L. and Cavalli, A. and Colizzi, F. and Belluti, F. and Bartolini, M. and Mancini, F. and Recanatini, M. and Andrisano, V. and others},
  title   = {{Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds}},
  journal = {Bioorganic \& medicinal chemistry letters},
  year    = {2008},
  doi     = {10.1016/j.bmcl.2007.09.100},
  pmid    = {17998161},
  url     = {https://doi.org/10.1016/j.bmcl.2007.09.100}
}

@article{pollock2007-17846102,
  author  = {Pollock, B. G. and Mulsant, B. H. and Rosen, J. and Mazumdar, S. and Blakesley, R. E. and Houck, P. R. and Huber, K. A.},
  title   = {{A double-blind comparison of citalopram and risperidone for the treatment of behavioral and psychotic symptoms associated with dementia}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2007},
  doi     = {10.1097/jgp.0b013e3180cc1ff5},
  pmid    = {17846102},
  url     = {https://doi.org/10.1097/jgp.0b013e3180cc1ff5}
}

@article{tweedie2007-17908040,
  author  = {Tweedie, D. and Sambamurti, K. and Greig, N. H.},
  title   = {{TNF-alpha inhibition as a treatment strategy for neurodegenerative disorders: new drug candidates and targets}},
  journal = {Current Alzheimer research},
  year    = {2007},
  doi     = {10.2174/156720507781788873},
  pmid    = {17908040},
  url     = {https://doi.org/10.2174/156720507781788873}
}

@article{jeste2008-17637610,
  author  = {Jeste, D. V. and Blazer, D. and Casey, D. and Meeks, T. and Salzman, C. and Schneider, L. and Tariot, P. and Yaffe, K.},
  title   = {{ACNP White Paper: update on use of antipsychotic drugs in elderly persons with dementia}},
  journal = {Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology},
  year    = {2008},
  doi     = {10.1038/sj.npp.1301492},
  pmid    = {17637610},
  url     = {https://doi.org/10.1038/sj.npp.1301492}
}

@article{blesa2007-17646620,
  author  = {Blesa, R. and Ballard, C. and Orgogozo, J. M. and Lane, R. and Thomas, S. K.},
  title   = {{Caregiver preference for rivastigmine patches versus capsules for the treatment of Alzheimer disease}},
  journal = {Neurology},
  year    = {2007},
  doi     = {10.1212/01.wnl.0000281848.25142.11},
  pmid    = {17646620},
  url     = {https://doi.org/10.1212/01.wnl.0000281848.25142.11}
}

@article{black2007-17664405,
  author  = {Black, S. E. and Doody, R. and Li, H. and McRae, T. and Jambor, K. M. and Xu, Y. and Sun, Y. and Perdomo, C. A. and others},
  title   = {{Donepezil preserves cognition and global function in patients with severe Alzheimer disease}},
  journal = {Neurology},
  year    = {2007},
  doi     = {10.1212/01.wnl.0000266627.96040.5a},
  pmid    = {17664405},
  url     = {https://doi.org/10.1212/01.wnl.0000266627.96040.5a}
}

@article{auchus2007-17664404,
  author  = {Auchus, A. P. and Brashear, H. R. and Salloway, S. and Korczyn, A. D. and De Deyn, P. P. and Gassmann-Mayer, C. and {GAL-INT-26 Study Group}},
  title   = {{Galantamine treatment of vascular dementia: a randomized trial}},
  journal = {Neurology},
  year    = {2007},
  doi     = {10.1212/01.wnl.0000266625.31615.f6},
  pmid    = {17664404},
  url     = {https://doi.org/10.1212/01.wnl.0000266625.31615.f6}
}

@article{feldman2007-17509485,
  author  = {Feldman, H. H. and Ferris, S. and Winblad, B. and Sfikas, N. and Mancione, L. and He, Y. and Tekin, S. and Burns, A. and others},
  title   = {{Effect of rivastigmine on delay to diagnosis of Alzheimer's disease from mild cognitive impairment: the InDDEx study}},
  journal = {The Lancet. Neurology},
  year    = {2007},
  doi     = {10.1016/s1474-4422(07)70109-6},
  pmid    = {17509485},
  url     = {https://doi.org/10.1016/s1474-4422(07)70109-6}
}

@article{study2007-17460158,
  author  = {{ADAPT Research Group} and Lyketsos, C. G. and Breitner, J. C. and Green, R. C. and Martin, B. K. and Meinert, C. and Piantadosi, S. and Sabbagh, M.},
  title   = {{Naproxen and celecoxib do not prevent AD in early results from a randomized controlled trial}},
  journal = {Neurology},
  year    = {2007},
  doi     = {10.1212/01.wnl.0000260269.93245.d2},
  pmid    = {17460158},
  url     = {https://doi.org/10.1212/01.wnl.0000260269.93245.d2}
}

@article{jack2008-17452062,
  author  = {Jack, C. R. and Petersen, R. C. and Grundman, M. and Jin, S. and Gamst, A. and Ward, C. P. and Sencakova, D. and Doody, R. S. and others},
  title   = {{Longitudinal MRI findings from the vitamin E and donepezil treatment study for MCI}},
  journal = {Neurobiology of aging},
  year    = {2008},
  doi     = {10.1016/j.neurobiolaging.2007.03.004},
  pmid    = {17452062},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2007.03.004}
}

@article{williamson2007-17599421,
  author  = {Williamson, J. D. and Miller, M. E. and Bryan, R. N. and Lazar, R. M. and Coker, L. H. and Johnson, J. and Cukierman, T. and Horowitz, K. R. and others},
  title   = {{The Action to Control Cardiovascular Risk in Diabetes Memory in Diabetes Study (ACCORD-MIND): rationale, design, and methods}},
  journal = {The American journal of cardiology},
  year    = {2007},
  doi     = {10.1016/j.amjcard.2007.03.029},
  pmid    = {17599421},
  url     = {https://doi.org/10.1016/j.amjcard.2007.03.029}
}

@article{vandyck2007-17545739,
  author  = {van Dyck, C. H. and Tariot, P. N. and Meyers, B. and Malca Resnick, E. and {Memantine MEM-MD-01 Study Group}},
  title   = {{A 24-week randomized, controlled trial of memantine in patients with moderate-to-severe Alzheimer disease}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2007},
  doi     = {10.1097/wad.0b013e318065c495},
  pmid    = {17545739},
  url     = {https://doi.org/10.1097/wad.0b013e318065c495}
}

@article{sampson2007-17006875,
  author  = {Sampson, E. L. and Raven, P. R. and Ndhlovu, P. N. and Vallance, A. and Garlick, N. and Watts, J. and Blanchard, M. R. and Bruce, A. and others},
  title   = {{A randomized, double-blind, placebo-controlled trial of donepezil hydrochloride (Aricept) for reducing the incidence of postoperative delirium after elective total hip replacement}},
  journal = {International journal of geriatric psychiatry},
  year    = {2007},
  doi     = {10.1002/gps.1679},
  pmid    = {17006875},
  url     = {https://doi.org/10.1002/gps.1679}
}

@article{rockwood2007-17404193,
  author  = {Rockwood, K. and Fay, S. and Jarrett, P. and Asp, E.},
  title   = {{Effect of galantamine on verbal repetition in AD: a secondary analysis of the VISTA trial}},
  journal = {Neurology},
  year    = {2007},
  doi     = {10.1212/01.wnl.0000258661.61577.b7},
  pmid    = {17404193},
  url     = {https://doi.org/10.1212/01.wnl.0000258661.61577.b7}
}

@article{rozzini2007-17117398,
  author  = {Rozzini, L. and Costardi, D. and Chilovi, B. V. and Franzoni, S. and Trabucchi, M. and Padovani, A.},
  title   = {{Efficacy of cognitive rehabilitation in patients with mild cognitive impairment treated with cholinesterase inhibitors}},
  journal = {International journal of geriatric psychiatry},
  year    = {2007},
  doi     = {10.1002/gps.1681},
  pmid    = {17117398},
  url     = {https://doi.org/10.1002/gps.1681}
}

@article{kurlan2007-17452579,
  author  = {Kurlan, R. and Cummings, J. and Raman, R. and Thal, L. and {Alzheimer's Disease Cooperative Study Group}},
  title   = {{Quetiapine for agitation or psychosis in patients with dementia and parkinsonism}},
  journal = {Neurology},
  year    = {2007},
  doi     = {10.1212/01.wnl.0000260060.60870.89},
  pmid    = {17452579},
  url     = {https://doi.org/10.1212/01.wnl.0000260060.60870.89}
}

@article{chappell2007-17389305,
  author  = {Chappell, A. S. and Gonzales, C. and Williams, J. and Witte, M. M. and Mohs, R. C. and Sperling, R.},
  title   = {{AMPA potentiator treatment of cognitive deficits in Alzheimer disease}},
  journal = {Neurology},
  year    = {2007},
  doi     = {10.1212/01.wnl.0000260240.46070.7c},
  pmid    = {17389305},
  url     = {https://doi.org/10.1212/01.wnl.0000260240.46070.7c}
}

@article{ollat2007-17675917,
  author  = {Ollat, H. and Laurent, B. and Bakchine, S. and Michel, B. F. and Touchon, J. and Dubois, B.},
  title   = {{[Effects of the association of sulbutiamine with an acetylcholinesterase inhibitor in early stage and moderate Alzheimer disease]}},
  journal = {L'Encephale},
  year    = {2007},
  doi     = {10.1016/s0013-7006(07)91552-3},
  pmid    = {17675917},
  url     = {https://doi.org/10.1016/s0013-7006(07)91552-3}
}

@article{zhong2007-17316169,
  author  = {Zhong, K. X. and Tariot, P. N. and Mintzer, J. and Minkwitz, M. C. and Devine, N. A.},
  title   = {{Quetiapine to treat agitation in dementia: a randomized, double-blind, placebo-controlled study}},
  journal = {Current Alzheimer research},
  year    = {2007},
  doi     = {10.2174/156720507779939805},
  pmid    = {17316169},
  url     = {https://doi.org/10.2174/156720507779939805}
}

@article{hager2007-17982894,
  author  = {Hager, K. and Kenklies, M. and McAfoose, J. and Engel, J. and Münch, G.},
  title   = {{Alpha-lipoic acid as a new treatment option for Alzheimer's disease--a 48 months follow-up analysis}},
  journal = {Journal of neural transmission. Supplementum},
  year    = {2007},
  doi     = {10.1007/978-3-211-73574-9_24},
  pmid    = {17982894},
  url     = {https://doi.org/10.1007/978-3-211-73574-9_24}
}

@article{pomara2007-17334274,
  author  = {Pomara, N. and Ott, B. R. and Peskind, E. and Resnick, E. M.},
  title   = {{Memantine treatment of cognitive symptoms in mild to moderate Alzheimer disease: secondary analyses from a placebo-controlled randomized trial}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2007},
  doi     = {10.1097/wad.0b013e318032cf29},
  pmid    = {17334274},
  url     = {https://doi.org/10.1097/wad.0b013e318032cf29}
}

@article{chow2007-19300592,
  author  = {Chow, T. W. and Pollock, B. G. and Milgram, N. W.},
  title   = {{Potential cognitive enhancing and disease modification effects of SSRIs for Alzheimer's disease}},
  journal = {Neuropsychiatric disease and treatment},
  year    = {2007},
  pmid    = {19300592}
}

@article{burn2006-16960863,
  author  = {Burn, D. and Emre, M. and McKeith, I. and De Deyn, P. P. and Aarsland, D. and Hsu, C. and Lane, R.},
  title   = {{Effects of rivastigmine in patients with and without visual hallucinations in dementia associated with Parkinson's disease}},
  journal = {Movement disorders : official journal of the Movement Disorder Society},
  year    = {2006},
  doi     = {10.1002/mds.21077},
  pmid    = {16960863},
  url     = {https://doi.org/10.1002/mds.21077}
}

@article{mioshi2006-16977673,
  author  = {Mioshi, E. and Dawson, K. and Mitchell, J. and Arnold, R. and Hodges, JR.},
  title   = {{The Addenbrooke's Cognitive Examination Revised (ACE-R): a brief cognitive test battery for dementia screening}},
  journal = {International journal of geriatric psychiatry},
  year    = {2006},
  doi     = {10.1002/gps.1610},
  pmid    = {16977673},
  url     = {https://doi.org/10.1002/gps.1610}
}

@article{vellas2006-17101932,
  author  = {Vellas, B. and Andrieu, S. and Ousset, P. J. and Ouzid, M. and Mathiex-Fortunet, H. and {GuidAge Study Group}},
  title   = {{The GuidAge study: methodological issues. A 5-year double-blind randomized trial of the efficacy of EGb 761 for prevention of Alzheimer disease in patients over 70 with a memory complaint}},
  journal = {Neurology},
  year    = {2006},
  doi     = {10.1212/wnl.67.9_suppl_3.s6},
  pmid    = {17101932},
  url     = {https://doi.org/10.1212/wnl.67.9_suppl_3.s6}
}

@article{feldman2006-17132971,
  author  = {Feldman, H. H. and Schmitt, F. A. and Olin, J. T. and {Memantine MEM-MD-02 Study Group}},
  title   = {{Activities of daily living in moderate-to-severe Alzheimer disease: an analysis of the treatment effects of memantine in patients receiving stable donepezil treatment}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2006},
  doi     = {10.1097/01.wad.0000213859.35355.59},
  pmid    = {17132971},
  url     = {https://doi.org/10.1097/01.wad.0000213859.35355.59}
}

@article{schmitt2006-17132970,
  author  = {Schmitt, F. A. and van Dyck, C. H. and Wichems, C. H. and Olin, J. T. and {Memantine MEM-MD-02 Study Group}},
  title   = {{Cognitive response to memantine in moderate to severe Alzheimer disease patients already receiving donepezil: an exploratory reanalysis}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2006},
  doi     = {10.1097/01.wad.0000213860.35355.d4},
  pmid    = {17132970},
  url     = {https://doi.org/10.1097/01.wad.0000213860.35355.d4}
}

@article{freundlevi2006-17030655,
  author  = {Freund-Levi, Y. and Eriksdotter-Jönhagen, M. and Cederholm, T. and Basun, H. and Faxén-Irving, G. and Garlind, A. and Vedin, I. and Vessby, B. and others},
  title   = {{Omega-3 fatty acid treatment in 174 patients with mild to moderate Alzheimer disease: OmegAD study: a randomized double-blind trial}},
  journal = {Archives of neurology},
  year    = {2006},
  doi     = {10.1001/archneur.63.10.1402},
  pmid    = {17030655},
  url     = {https://doi.org/10.1001/archneur.63.10.1402}
}

@article{mazza2006-16930364,
  author  = {Mazza, M. and Capuano, A. and Bria, P. and Mazza, S.},
  title   = {{Ginkgo biloba and donepezil: a comparison in the treatment of Alzheimer's dementia in a randomized placebo-controlled double-blind study}},
  journal = {European journal of neurology},
  year    = {2006},
  doi     = {10.1111/j.1468-1331.2006.01409.x},
  pmid    = {16930364},
  url     = {https://doi.org/10.1111/j.1468-1331.2006.01409.x}
}

@article{tariot2006-16905684,
  author  = {Tariot, P. N. and Schneider, L. and Katz, I. R. and Mintzer, J. E. and Street, J. and Copenhaver, M. and Williams-Hughes, C.},
  title   = {{Quetiapine treatment of psychosis associated with dementia: a double-blind, randomized, placebo-controlled clinical trial}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2006},
  doi     = {10.1097/01.jgp.0000196628.12010.35},
  pmid    = {16905684},
  url     = {https://doi.org/10.1097/01.jgp.0000196628.12010.35}
}

@article{peskind2006-16861375,
  author  = {Peskind, E. R. and Potkin, S. G. and Pomara, N. and Ott, B. R. and Graham, S. M. and Olin, J. T. and McDonald, S.},
  title   = {{Memantine treatment in mild to moderate Alzheimer disease: a 24-week randomized, controlled trial}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2006},
  doi     = {10.1097/01.jgp.0000224350.82719.83},
  pmid    = {16861375},
  url     = {https://doi.org/10.1097/01.jgp.0000224350.82719.83}
}

@article{vandyck2006-16670247,
  author  = {van Dyck, C. H. and Schmitt, F. A. and Olin, J. T. and {Memantine MEM-MD-02 Study Group}},
  title   = {{A responder analysis of memantine treatment in patients with Alzheimer disease maintained on donepezil}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2006},
  doi     = {10.1097/01.jgp.0000203151.17311.38},
  pmid    = {16670247},
  url     = {https://doi.org/10.1097/01.jgp.0000203151.17311.38}
}

@article{hu2006-16780671,
  author  = {Hu, H. T. and Zhang, Z. X. and Yao, J. L. and Yu, H. Z. and Wang, Y. H. and Tang, H. C. and Ji, C. J. and Xu, T.},
  title   = {{[Clinical efficacy and safety of akatinol memantine in treatment of mild to moderate Alzheimer disease: a donepezil-controlled, randomized trial]}},
  journal = {Zhonghua nei ke za zhi},
  year    = {2006},
  pmid    = {16780671}
}

@article{rockwood2006-16554498,
  author  = {Rockwood, K. and Fay, S. and Song, X. and MacKnight, C. and Gorman, M.},
  title   = {{Attainment of treatment goals by people with Alzheimer's disease receiving galantamine: a randomized controlled trial}},
  journal = {CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne},
  year    = {2006},
  doi     = {10.1503/cmaj.051432},
  pmid    = {16554498},
  url     = {https://doi.org/10.1503/cmaj.051432}
}

@article{schneider2006-16505124,
  author  = {Schneider, L. S. and Dagerman, K. and Insel, P. S.},
  title   = {{Efficacy and adverse effects of atypical antipsychotics for dementia: meta-analysis of randomized, placebo-controlled trials}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2006},
  doi     = {10.1097/01.jgp.0000200589.01396.6d},
  pmid    = {16505124},
  url     = {https://doi.org/10.1097/01.jgp.0000200589.01396.6d}
}

@article{mintzer2006-16505133,
  author  = {Mintzer, J. and Greenspan, A. and Caers, I. and Van Hove, I. and Kushner, S. and Weiner, M. and Gharabawi, G. and Schneider, L. S.},
  title   = {{Risperidone in the treatment of psychosis of Alzheimer disease: results from a prospective clinical trial}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2006},
  doi     = {10.1097/01.jgp.0000194643.63245.8c},
  pmid    = {16505133},
  url     = {https://doi.org/10.1097/01.jgp.0000194643.63245.8c}
}

@article{benedetti2006-16473462,
  author  = {Benedetti, F. and Arduino, C. and Costa, S. and Vighetti, S. and Tarenzi, L. and Rainero, I. and Asteggiano, G.},
  title   = {{Loss of expectation-related mechanisms in Alzheimer's disease makes analgesic therapies less effective}},
  journal = {Pain},
  year    = {2006},
  doi     = {10.1016/j.pain.2005.12.016},
  pmid    = {16473462},
  url     = {https://doi.org/10.1016/j.pain.2005.12.016}
}

@article{ayalon2006-16473983,
  author  = {Ayalon, L. and Ancoli-Israel, S. and Stepnowsky, C. and Marler, M. and Palmer, B. W. and Liu, L. and Loredo, J. S. and Corey-Bloom, J. and others},
  title   = {{Adherence to continuous positive airway pressure treatment in patients with Alzheimer's disease and obstructive sleep apnea}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2006},
  doi     = {10.1097/01.jgp.0000192484.12684.cd},
  pmid    = {16473983},
  url     = {https://doi.org/10.1097/01.jgp.0000192484.12684.cd}
}

@article{siemers2006-16505324,
  author  = {Siemers, E. R. and Quinn, J. F. and Kaye, J. and Farlow, M. R. and Porsteinsson, A. and Tariot, P. and Zoulnouni, P. and Galvin, J. E. and others},
  title   = {{Effects of a gamma-secretase inhibitor in a randomized study of patients with Alzheimer disease}},
  journal = {Neurology},
  year    = {2006},
  doi     = {10.1212/01.wnl.0000198762.41312.e1},
  pmid    = {16505324},
  url     = {https://doi.org/10.1212/01.wnl.0000198762.41312.e1}
}

@article{birks2006-16437532,
  author  = {Birks, J.},
  title   = {{Cholinesterase inhibitors for Alzheimer's disease}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2006},
  doi     = {10.1002/14651858.cd005593},
  pmid    = {16437532},
  url     = {https://doi.org/10.1002/14651858.cd005593}
}

@article{birks2006-16437430,
  author  = {Birks, J. and Harvey, R. J.},
  title   = {{Donepezil for dementia due to Alzheimer's disease}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2006},
  doi     = {10.1002/14651858.cd001190.pub2},
  pmid    = {16437430},
  url     = {https://doi.org/10.1002/14651858.cd001190.pub2}
}

@article{loy2006-16437436,
  author  = {Loy, C. and Schneider, L.},
  title   = {{Galantamine for Alzheimer's disease and mild cognitive impairment}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2006},
  doi     = {10.1002/14651858.cd001747.pub3},
  pmid    = {16437436},
  url     = {https://doi.org/10.1002/14651858.cd001747.pub3}
}

@article{ballard2006-16437455,
  author  = {Ballard, C. and Waite, J.},
  title   = {{The effectiveness of atypical antipsychotics for the treatment of aggression and psychosis in Alzheimer's disease}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2006},
  doi     = {10.1002/14651858.cd003476.pub2},
  pmid    = {16437455},
  url     = {https://doi.org/10.1002/14651858.cd003476.pub2}
}

@article{reisberg2006-16401736,
  author  = {Reisberg, B. and Doody, R. and Stöffler, A. and Schmitt, F. and Ferris, S. and Möbius, H. J.},
  title   = {{A 24-week open-label extension study of memantine in moderate to severe Alzheimer disease}},
  journal = {Archives of neurology},
  year    = {2006},
  doi     = {10.1001/archneur.63.1.49},
  pmid    = {16401736},
  url     = {https://doi.org/10.1001/archneur.63.1.49}
}

@article{sparks2006-16866904,
  author  = {Sparks, D. L. and Connor, D. J. and Sabbagh, M. N. and Petersen, R. B. and Lopez, J. and Browne, P.},
  title   = {{Circulating cholesterol levels, apolipoprotein E genotype and dementia severity influence the benefit of atorvastatin treatment in Alzheimer's disease: results of the Alzheimer's Disease Cholesterol-Lowering Treatment (ADCLT) trial}},
  journal = {Acta neurologica Scandinavica. Supplementum},
  year    = {2006},
  doi     = {10.1111/j.1600-0404.2006.00690.x},
  pmid    = {16866904},
  url     = {https://doi.org/10.1111/j.1600-0404.2006.00690.x}
}

@article{wang2006-16364207,
  author  = {Wang, R. and Yan, H. and Tang, X. C.},
  title   = {{Progress in studies of huperzine A, a natural cholinesterase inhibitor from Chinese herbal medicine}},
  journal = {Acta pharmacologica Sinica},
  year    = {2006},
  doi     = {10.1111/j.1745-7254.2006.00255.x},
  pmid    = {16364207},
  url     = {https://doi.org/10.1111/j.1745-7254.2006.00255.x}
}

@article{muir2006-16359918,
  author  = {Muir, K. W.},
  title   = {{Glutamate-based therapeutic approaches: clinical trials with NMDA antagonists}},
  journal = {Current opinion in pharmacology},
  year    = {2006},
  doi     = {10.1016/j.coph.2005.12.002},
  pmid    = {16359918},
  url     = {https://doi.org/10.1016/j.coph.2005.12.002}
}

@article{schneider2005-16375657,
  author  = {Schneider, L. S. and DeKosky, S. T. and Farlow, M. R. and Tariot, P. N. and Hoerr, R. and Kieser, M.},
  title   = {{A randomized, double-blind, placebo-controlled trial of two doses of Ginkgo biloba extract in dementia of the Alzheimer's type}},
  journal = {Current Alzheimer research},
  year    = {2005},
  doi     = {10.2174/156720505774932287},
  pmid    = {16375657},
  url     = {https://doi.org/10.2174/156720505774932287}
}

@article{kay2005-16398909,
  author  = {Kay, G. G. and Abou-Donia, M. B. and Messer, W. S. and Murphy, D. G. and Tsao, J. W. and Ouslander, J. G.},
  title   = {{Antimuscarinic drugs for overactive bladder and their potential effects on cognitive function in older patients}},
  journal = {Journal of the American Geriatrics Society},
  year    = {2005},
  doi     = {10.1111/j.1532-5415.2005.00537.x},
  pmid    = {16398909},
  url     = {https://doi.org/10.1111/j.1532-5415.2005.00537.x}
}

@article{tariot2005-16286437,
  author  = {Tariot, P. N. and Raman, R. and Jakimovich, L. and Schneider, L. and Porsteinsson, A. and Thomas, R. and Mintzer, J. and Brenner, R. and others},
  title   = {{Divalproex sodium in nursing home residents with possible or probable Alzheimer Disease complicated by agitation: a randomized, controlled trial}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2005},
  doi     = {10.1176/appi.ajgp.13.11.942},
  pmid    = {16286437},
  url     = {https://doi.org/10.1176/appi.ajgp.13.11.942}
}

@article{watson2005-16286438,
  author  = {Watson, G. S. and Cholerton, B. A. and Reger, M. A. and Baker, L. D. and Plymate, SR. and Asthana, S. and Fishel, M. A. and Kulstad, J. J. and others},
  title   = {{Preserved cognition in patients with early Alzheimer disease and amnestic mild cognitive impairment during treatment with rosiglitazone: a preliminary study}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2005},
  doi     = {10.1176/appi.ajgp.13.11.950},
  pmid    = {16286438},
  url     = {https://doi.org/10.1176/appi.ajgp.13.11.950}
}

@article{onder2005-16260821,
  author  = {Onder, G. and Zanetti, O. and Giacobini, E. and Frisoni, G. B. and Bartorelli, L. and Carbone, G. and Lambertucci, P. and others},
  title   = {{Reality orientation therapy combined with cholinesterase inhibitors in Alzheimer's disease: randomised controlled trial}},
  journal = {The British journal of psychiatry : the journal of mental science},
  year    = {2005},
  doi     = {10.1192/bjp.187.5.450},
  pmid    = {16260821},
  url     = {https://doi.org/10.1192/bjp.187.5.450}
}

@article{goekoop2006-16251213,
  author  = {Goekoop, R. and Scheltens, P. and Barkhof, F. and Rombouts, S. A.},
  title   = {{Cholinergic challenge in Alzheimer patients and mild cognitive impairment differentially affects hippocampal activation--a pharmacological fMRI study}},
  journal = {Brain : a journal of neurology},
  year    = {2006},
  doi     = {10.1093/brain/awh671},
  pmid    = {16251213},
  url     = {https://doi.org/10.1093/brain/awh671}
}

@article{schneider2005-16234500,
  author  = {Schneider, L. S. and Dagerman, K. S. and Insel, P.},
  title   = {{Risk of death with atypical antipsychotic drug treatment for dementia: meta-analysis of randomized placebo-controlled trials}},
  journal = {JAMA},
  year    = {2005},
  doi     = {10.1001/jama.294.15.1934},
  pmid    = {16234500},
  url     = {https://doi.org/10.1001/jama.294.15.1934}
}

@article{sato2005-16087821,
  author  = {Sato, Y. and Kanoko, T. and Satoh, K. and Iwamoto, J.},
  title   = {{The prevention of hip fracture with risedronate and ergocalciferol plus calcium supplementation in elderly women with Alzheimer disease: a randomized controlled trial}},
  journal = {Archives of internal medicine},
  year    = {2005},
  doi     = {10.1001/archinte.165.15.1737},
  pmid    = {16087821},
  url     = {https://doi.org/10.1001/archinte.165.15.1737}
}

@article{sparks2005-15974900,
  author  = {Sparks, D. L. and Sabbagh, M. N. and Connor, D. J. and Lopez, J. and Launer, L. J. and Petanceska, S. and Browne, P. and Wassar, D. and others},
  title   = {{Atorvastatin therapy lowers circulating cholesterol but not free radical activity in advance of identifiable clinical benefit in the treatment of mild-to-moderate AD}},
  journal = {Current Alzheimer research},
  year    = {2005},
  doi     = {10.2174/1567205054367900},
  pmid    = {15974900},
  url     = {https://doi.org/10.2174/1567205054367900}
}

@article{sparks2005-15883262,
  author  = {Sparks, D. L. and Sabbagh, M. N. and Connor, D. J. and Lopez, J. and Launer, L. J. and Browne, P. and Wasser, D. and Johnson-Traver, S. and others},
  title   = {{Atorvastatin for the treatment of mild to moderate Alzheimer disease: preliminary results}},
  journal = {Archives of neurology},
  year    = {2005},
  doi     = {10.1001/archneur.62.5.753},
  pmid    = {15883262},
  url     = {https://doi.org/10.1001/archneur.62.5.753}
}

@article{gilman2005-15883316,
  author  = {Gilman, S. and Koller, M. and Black, R. S. and Jenkins, L. and Griffith, S. G. and Fox, N. C. and Eisner, L. and Kirby, L. and others},
  title   = {{Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial}},
  journal = {Neurology},
  year    = {2005},
  doi     = {10.1212/01.wnl.0000159740.16984.3c},
  pmid    = {15883316},
  url     = {https://doi.org/10.1212/01.wnl.0000159740.16984.3c}
}

@article{fox2005-15883317,
  author  = {Fox, N. C. and Black, R. S. and Gilman, S. and Rossor, M. N. and Griffith, S. G. and Jenkins, L. and Koller, M.},
  title   = {{Effects of Abeta immunization (AN1792) on MRI measures of cerebral volume in Alzheimer disease}},
  journal = {Neurology},
  year    = {2005},
  doi     = {10.1212/01.wnl.0000159743.08996.99},
  pmid    = {15883317},
  url     = {https://doi.org/10.1212/01.wnl.0000159743.08996.99}
}

@article{mccurry2005-15877554,
  author  = {McCurry, S. M. and Gibbons, L. E. and Logsdon, R. G. and Vitiello, M. V. and Teri, L.},
  title   = {{Nighttime insomnia treatment and education for Alzheimer's disease: a randomized, controlled trial}},
  journal = {Journal of the American Geriatrics Society},
  year    = {2005},
  doi     = {10.1111/j.1532-5415.2005.53252.x},
  pmid    = {15877554},
  url     = {https://doi.org/10.1111/j.1532-5415.2005.53252.x}
}

@article{petersen2005-15829527,
  author  = {Petersen, R. C. and Thomas, R. G. and Grundman, M. and Bennett, D. and Doody, R. and Ferris, S. and Galasko, D. and Jin, S. and others},
  title   = {{Vitamin E and donepezil for the treatment of mild cognitive impairment}},
  journal = {The New England journal of medicine},
  year    = {2005},
  doi     = {10.1056/nejmoa050151},
  pmid    = {15829527},
  url     = {https://doi.org/10.1056/nejmoa050151}
}

@article{hashimoto2005-15800138,
  author  = {Hashimoto, M. and Kazui, H. and Matsumoto, K. and Nakano, Y. and Yasuda, M. and Mori, E.},
  title   = {{Does donepezil treatment slow the progression of hippocampal atrophy in patients with Alzheimer's disease?}},
  journal = {The American journal of psychiatry},
  year    = {2005},
  doi     = {10.1176/appi.ajp.162.4.676},
  pmid    = {15800138},
  url     = {https://doi.org/10.1176/appi.ajp.162.4.676}
}

@article{yaffe2005-15800139,
  author  = {Yaffe, K. and Krueger, K. and Cummings, SR. and Blackwell, T. and Henderson, V. W. and Sarkar, S. and Ensrud, K. and Grady, D.},
  title   = {{Effect of raloxifene on prevention of dementia and cognitive impairment in older women: the Multiple Outcomes of Raloxifene Evaluation (MORE) randomized trial}},
  journal = {The American journal of psychiatry},
  year    = {2005},
  doi     = {10.1176/appi.ajp.162.4.683},
  pmid    = {15800139},
  url     = {https://doi.org/10.1176/appi.ajp.162.4.683}
}

@article{iwasaki2005-15705012,
  author  = {Iwasaki, K. and Satoh-Nakagawa, T. and Maruyama, M. and Monma, Y. and Nemoto, M. and Tomita, N. and Tanji, H. and Fujiwara, H. and others},
  title   = {{A randomized, observer-blind, controlled trial of the traditional Chinese medicine Yi-Gan San for improvement of behavioral and psychological symptoms and activities of daily living in dementia patients}},
  journal = {The Journal of clinical psychiatry},
  year    = {2005},
  doi     = {10.4088/jcp.v66n0214},
  pmid    = {15705012},
  url     = {https://doi.org/10.4088/jcp.v66n0214}
}

@article{bayer2005-15642910,
  author  = {Bayer, A. J. and Bullock, R. and Jones, R. W. and Wilkinson, D. and Paterson, K. R. and Jenkins, L. and Millais, S. B. and Donoghue, S.},
  title   = {{Evaluation of the safety and immunogenicity of synthetic Abeta42 (AN1792) in patients with AD}},
  journal = {Neurology},
  year    = {2005},
  doi     = {10.1212/01.wnl.0000148604.77591.67},
  pmid    = {15642910},
  url     = {https://doi.org/10.1212/01.wnl.0000148604.77591.67}
}

@article{chao2005-15668426,
  author  = {Chao, L. L. and Schuff, N. and Kramer, J. H. and Du, A. T. and Capizzano, A. A. and O'Neill, J. and Wolkowitz, O. M. and Jagust, W. J. and others},
  title   = {{Reduced medial temporal lobe N-acetylaspartate in cognitively impaired but nondemented patients}},
  journal = {Neurology},
  year    = {2005},
  doi     = {10.1212/01.wnl.0000149638.45635.ff},
  pmid    = {15668426},
  url     = {https://doi.org/10.1212/01.wnl.0000149638.45635.ff}
}

@article{seltzer2004-15596605,
  author  = {Seltzer, B. and Zolnouni, P. and Nunez, M. and Goldman, R. and Kumar, D. and Ieni, J. and Richardson, S. and {Donepezil "402" Study Group}},
  title   = {{Efficacy of donepezil in early-stage Alzheimer disease: a randomized placebo-controlled trial}},
  journal = {Archives of neurology},
  year    = {2004},
  doi     = {10.1001/archneur.61.12.1852},
  pmid    = {15596605},
  url     = {https://doi.org/10.1001/archneur.61.12.1852}
}

@article{gong2004-15578094,
  author  = {Gong, B. and Vitolo, O. V. and Trinchese, F. and Liu, S. and Shelanski, M. and Arancio, O.},
  title   = {{Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment}},
  journal = {The Journal of clinical investigation},
  year    = {2004},
  doi     = {10.1172/jci22831},
  pmid    = {15578094},
  url     = {https://doi.org/10.1172/jci22831}
}

@article{emre2004-15590953,
  author  = {Emre, M. and Aarsland, D. and Albanese, A. and Byrne, E. J. and Deuschl, G. and De Deyn, P. P. and Durif, F. and Kulisevsky, J. and others},
  title   = {{Rivastigmine for dementia associated with Parkinson's disease}},
  journal = {The New England journal of medicine},
  year    = {2004},
  doi     = {10.1056/nejmoa041470},
  pmid    = {15590953},
  url     = {https://doi.org/10.1056/nejmoa041470}
}

@article{politis2004-15481065,
  author  = {Politis, A. M. and Vozzella, S. and Mayer, L. S. and Onyike, C. U. and Baker, A. S. and Lyketsos, C. G.},
  title   = {{A randomized, controlled, clinical trial of activity therapy for apathy in patients with dementia residing in long-term care}},
  journal = {International journal of geriatric psychiatry},
  year    = {2004},
  doi     = {10.1002/gps.1215},
  pmid    = {15481065},
  url     = {https://doi.org/10.1002/gps.1215}
}

@article{feldman2004-15326236,
  author  = {Feldman, H. and Gauthier, S. and Hecker, J. and Vellas, B. and Hux, M. and Xu, Y. and Schwam, E. M. and Shah, S. and others},
  title   = {{Economic evaluation of donepezil in moderate to severe Alzheimer disease}},
  journal = {Neurology},
  year    = {2004},
  doi     = {10.1212/01.wnl.0000134663.79663.6e},
  pmid    = {15326236},
  url     = {https://doi.org/10.1212/01.wnl.0000134663.79663.6e}
}

@article{salloway2004-15326237,
  author  = {Salloway, S. and Ferris, S. and Kluger, A. and Goldman, R. and Griesing, T. and Kumar, D. and Richardson, S. and {Donepezil 401 Study Group}},
  title   = {{Efficacy of donepezil in mild cognitive impairment: a randomized placebo-controlled trial}},
  journal = {Neurology},
  year    = {2004},
  doi     = {10.1212/01.wnl.0000134664.80320.92},
  pmid    = {15326237},
  url     = {https://doi.org/10.1212/01.wnl.0000134664.80320.92}
}

@article{ritchie2004-15249273,
  author  = {Ritchie, C. W. and Ames, D. and Clayton, T. and Lai, R.},
  title   = {{Metaanalysis of randomized trials of the efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer disease}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2004},
  doi     = {10.1176/appi.ajgp.12.4.358},
  pmid    = {15249273},
  url     = {https://doi.org/10.1176/appi.ajgp.12.4.358}
}

@article{szekely2004-15279021,
  author  = {Szekely, C. A. and Thorne, J. E. and Zandi, P. P. and Ek, M. and Messias, E. and Breitner, J. C. and Goodman, S. N.},
  title   = {{Nonsteroidal anti-inflammatory drugs for the prevention of Alzheimer's disease: a systematic review}},
  journal = {Neuroepidemiology},
  year    = {2004},
  doi     = {10.1159/000078501},
  pmid    = {15279021},
  url     = {https://doi.org/10.1159/000078501}
}

@article{otto2004-15007119,
  author  = {Otto, M. and Cepek, L. and Ratzka, P. and Doehlinger, S. and Boekhoff, I. and Wiltfang, J. and Irle, E. and Pergande, G. and others},
  title   = {{Efficacy of flupirtine on cognitive function in patients with CJD: A double-blind study}},
  journal = {Neurology},
  year    = {2004},
  doi     = {10.1212/01.wnl.0000113764.35026.ef},
  pmid    = {15007119},
  url     = {https://doi.org/10.1212/01.wnl.0000113764.35026.ef}
}

@article{raskind2004-14967774,
  author  = {Raskind, M. A. and Peskind, E. R. and Truyen, L. and Kershaw, P. and Damaraju, C. V.},
  title   = {{The cognitive benefits of galantamine are sustained for at least 36 months: a long-term extension trial}},
  journal = {Archives of neurology},
  year    = {2004},
  doi     = {10.1001/archneur.61.2.252},
  pmid    = {14967774},
  url     = {https://doi.org/10.1001/archneur.61.2.252}
}

@article{lipton2004-15717010,
  author  = {Lipton, S. A.},
  title   = {{Failures and successes of NMDA receptor antagonists: molecular basis for the use of open-channel blockers like memantine in the treatment of acute and chronic neurologic insults}},
  journal = {NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics},
  year    = {2004},
  doi     = {10.1602/neurorx.1.1.101},
  pmid    = {15717010},
  url     = {https://doi.org/10.1602/neurorx.1.1.101}
}

@article{tariot2004-14734594,
  author  = {Tariot, P. N. and Farlow, M. R. and Grossberg, G. T. and Graham, S. M. and McDonald, S. and Gergel, I. and {Memantine Study Group}},
  title   = {{Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: a randomized controlled trial}},
  journal = {JAMA},
  year    = {2004},
  doi     = {10.1001/jama.291.3.317},
  pmid    = {14734594},
  url     = {https://doi.org/10.1001/jama.291.3.317}
}

@article{zandi2004-14732624,
  author  = {Zandi, P. P. and Anthony, J. C. and Khachaturian, A. S. and Stone, S. V. and Gustafson, D. and Tschanz, J. T. and Norton, M. C. and Welsh-Bohmer, K. A. and others},
  title   = {{Reduced risk of Alzheimer disease in users of antioxidant vitamin supplements: the Cache County Study}},
  journal = {Archives of neurology},
  year    = {2004},
  doi     = {10.1001/archneur.61.1.82},
  pmid    = {14732624},
  url     = {https://doi.org/10.1001/archneur.61.1.82}
}

@article{reines2004-14718699,
  author  = {Reines, S. A. and Block, G. A. and Morris, J. C. and Liu, G. and Nessly, M. L. and Lines, C. R. and Norman, B. A. and Baranak, C. C. and others},
  title   = {{Rofecoxib: no effect on Alzheimer's disease in a 1-year, randomized, blinded, controlled study}},
  journal = {Neurology},
  year    = {2004},
  doi     = {10.1212/wnl.62.1.66},
  pmid    = {14718699},
  url     = {https://doi.org/10.1212/wnl.62.1.66}
}

@article{ritchie2003-14676042,
  author  = {Ritchie, C. W. and Bush, A. I. and Mackinnon, A. and Macfarlane, S. and Mastwyk, M. and MacGregor, L. and Kiers, L. and Cherny, R. and others},
  title   = {{Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial}},
  journal = {Archives of neurology},
  year    = {2003},
  doi     = {10.1001/archneur.60.12.1685},
  pmid    = {14676042},
  url     = {https://doi.org/10.1001/archneur.60.12.1685}
}

@article{kanowski2003-14663654,
  author  = {Kanowski, S. and Hoerr, R.},
  title   = {{Ginkgo biloba extract EGb 761 in dementia: intent-to-treat analyses of a 24-week, multi-center, double-blind, placebo-controlled, randomized trial}},
  journal = {Pharmacopsychiatry},
  year    = {2003},
  doi     = {10.1055/s-2003-45117},
  pmid    = {14663654},
  url     = {https://doi.org/10.1055/s-2003-45117}
}

@article{krishnan2003-14594748,
  author  = {Krishnan, K. R. and Charles, H. C. and Doraiswamy, P. M. and Mintzer, J. and Weisler, R. and Yu, X. and Perdomo, C. and Ieni, JR. and others},
  title   = {{Randomized, placebo-controlled trial of the effects of donepezil on neuronal markers and hippocampal volumes in Alzheimer's disease}},
  journal = {The American journal of psychiatry},
  year    = {2003},
  doi     = {10.1176/appi.ajp.160.11.2003},
  pmid    = {14594748},
  url     = {https://doi.org/10.1176/appi.ajp.160.11.2003}
}

@article{teri2003-14559955,
  author  = {Teri, L. and Gibbons, L. E. and McCurry, S. M. and Logsdon, R. G. and Buchner, D. M. and Barlow, W. E. and Kukull, W. A. and LaCroix, A. Z. and others},
  title   = {{Exercise plus behavioral management in patients with Alzheimer disease: a randomized controlled trial}},
  journal = {JAMA},
  year    = {2003},
  doi     = {10.1001/jama.290.15.2015},
  pmid    = {14559955},
  url     = {https://doi.org/10.1001/jama.290.15.2015}
}

@article{black2003-12970516,
  author  = {Black, S. and Román, G. C. and Geldmacher, D. S. and Salloway, S. and Hecker, J. and Burns, A. and Perdomo, C. and Kumar, D. and others},
  title   = {{Efficacy and tolerability of donepezil in vascular dementia: positive results of a 24-week, multicenter, international, randomized, placebo-controlled clinical trial}},
  journal = {Stroke},
  year    = {2003},
  doi     = {10.1161/01.str.0000091396.95360.e1},
  pmid    = {12970516},
  url     = {https://doi.org/10.1161/01.str.0000091396.95360.e1}
}

@article{wilkinson2003-12939421,
  author  = {Wilkinson, D. and Doody, R. and Helme, R. and Taubman, K. and Mintzer, J. and Kertesz, A. and Pratt, R. D. and {Donepezil 308 Study Group}},
  title   = {{Donepezil in vascular dementia: a randomized, placebo-controlled study}},
  journal = {Neurology},
  year    = {2003},
  doi     = {10.1212/01.wnl.0000078943.50032.fc},
  pmid    = {12939421},
  url     = {https://doi.org/10.1212/01.wnl.0000078943.50032.fc}
}

@article{orgogozo2003-12847155,
  author  = {Orgogozo, Jean Marc and Gilman, Sid and Dartigues, Jean‐François and Laurent, Bernard and Puel, Michèle and Kirby, Lachlan and Jouanny, P. and Dubois, Bruno and Eisner, L. and Flitman, Stephen S. and Michel, Bernard‐François and Boada, Merçé and Frank, Ana and Hock, C.},
  title   = {{Subacute meningoencephalitis in a subset of patients with AD after Aβ42 immunization}},
  journal = {Neurology},
  year    = {2003},
  doi     = {10.1212/01.wnl.0000073623.84147.a8},
  pmid    = {12847155},
  url     = {https://doi.org/10.1212/01.wnl.0000073623.84147.a8}
}

@article{geldmacher2003-12834513,
  author  = {Geldmacher, D. S. and Provenzano, G. and McRae, T. and Mastey, V. and Ieni, JR.},
  title   = {{Donepezil is associated with delayed nursing home placement in patients with Alzheimer's disease}},
  journal = {Journal of the American Geriatrics Society},
  year    = {2003},
  doi     = {10.1046/j.1365-2389.2003.51306.x},
  pmid    = {12834513},
  url     = {https://doi.org/10.1046/j.1365-2389.2003.51306.x}
}

@article{akhondzadeh2003-12810768,
  author  = {Akhondzadeh, S. and Noroozian, M. and Mohammadi, M. and Ohadinia, S. and Jamshidi, A. H. and Khani, M.},
  title   = {{Melissa officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomised, placebo controlled trial}},
  journal = {Journal of neurology, neurosurgery, and psychiatry},
  year    = {2003},
  doi     = {10.1136/jnnp.74.7.863},
  pmid    = {12810768},
  url     = {https://doi.org/10.1136/jnnp.74.7.863}
}

@article{lyketsos2003-12860778,
  author  = {Lyketsos, C. G. and DelCampo, L. and Steinberg, M. and Miles, Q. and Steele, C. D. and Munro, C. and Baker, A. S. and Sheppard, J. M. and others},
  title   = {{Treating depression in Alzheimer disease: efficacy and safety of sertraline therapy, and the benefits of depression reduction: the DIADS}},
  journal = {Archives of general psychiatry},
  year    = {2003},
  doi     = {10.1001/archpsyc.60.7.737},
  pmid    = {12860778},
  url     = {https://doi.org/10.1001/archpsyc.60.7.737}
}

@article{aisen2003-12783912,
  author  = {Aisen, P. S. and Schafer, K. A. and Grundman, M. and Pfeiffer, E. and Sano, M. and Davis, K. L. and Farlow, M. R. and Jin, S. and others},
  title   = {{Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial}},
  journal = {JAMA},
  year    = {2003},
  doi     = {10.1001/jama.289.21.2819},
  pmid    = {12783912},
  url     = {https://doi.org/10.1001/jama.289.21.2819}
}

@article{feldman2003-12757558,
  author  = {Feldman, H. and Gauthier, S. and Hecker, J. and Vellas, B. and Emir, B. and Mastey, V. and Subbiah, P. and {Donepezil MSAD Study Investigators Group}},
  title   = {{Efficacy of donepezil on maintenance of activities of daily living in patients with moderate to severe Alzheimer's disease and the effect on caregiver burden}},
  journal = {Journal of the American Geriatrics Society},
  year    = {2003},
  doi     = {10.1046/j.1365-2389.2003.51260.x},
  pmid    = {12757558},
  url     = {https://doi.org/10.1046/j.1365-2389.2003.51260.x}
}

@article{perry2003-12895683,
  author  = {Perry, N. S. and Bollen, C. and Perry, E. K. and Ballard, C.},
  title   = {{Salvia for dementia therapy: review of pharmacological activity and pilot tolerability clinical trial}},
  journal = {Pharmacology, biochemistry, and behavior},
  year    = {2003},
  doi     = {10.1016/s0091-3057(03)00108-4},
  pmid    = {12895683},
  url     = {https://doi.org/10.1016/s0091-3057(03)00108-4}
}

@article{tzourio2003-12742805,
  author  = {Tzourio, C. and Anderson, C. and Chapman, N. and Woodward, M. and Neal, B. and MacMahon, S. and Chalmers, J. and {PROGRESS Collaborative Group}},
  title   = {{Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease}},
  journal = {Archives of internal medicine},
  year    = {2003},
  doi     = {10.1001/archinte.163.9.1069},
  pmid    = {12742805},
  url     = {https://doi.org/10.1001/archinte.163.9.1069}
}

@article{vandongen2003-12767414,
  author  = {van Dongen, M. and van Rossum, E. and Kessels, A. and Sielhorst, H. and Knipschild, P.},
  title   = {{Ginkgo for elderly people with dementia and age-associated memory impairment: a randomized clinical trial}},
  journal = {Journal of clinical epidemiology},
  year    = {2003},
  doi     = {10.1016/s0895-4356(03)00003-9},
  pmid    = {12767414},
  url     = {https://doi.org/10.1016/s0895-4356(03)00003-9}
}

@article{reisberg2003-12672860,
  author  = {Reisberg, B. and Doody, R. and Stöffler, A. and Schmitt, F. and Ferris, S. and Möbius, H. J. and {Memantine Study Group}},
  title   = {{Memantine in moderate-to-severe Alzheimer's disease}},
  journal = {The New England journal of medicine},
  year    = {2003},
  doi     = {10.1056/nejmoa013128},
  pmid    = {12672860},
  url     = {https://doi.org/10.1056/nejmoa013128}
}

@article{baker2003-12611754,
  author  = {Baker, L. D. and Sambamurti, K. and Craft, S. and Cherrier, M. and Raskind, M. A. and Stanczyk, F. Z. and Plymate, SR. and Asthana, S.},
  title   = {{17beta-estradiol reduces plasma Abeta40 for HRT-naïve postmenopausal women with Alzheimer disease: a preliminary study}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2003},
  doi     = {10.1097/00019442-200303000-00015},
  pmid    = {12611754},
  url     = {https://doi.org/10.1097/00019442-200303000-00015}
}

@article{pelton2003-12611748,
  author  = {Pelton, G. H. and Devanand, D. P. and Bell, K. and Marder, K. and Marston, K. and Liu, X. and Cooper, T. B.},
  title   = {{Usefulness of plasma haloperidol levels for monitoring clinical efficacy and side effects in Alzheimer patients with psychosis and behavioral dyscontrol}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2003},
  doi     = {10.1176/appi.ajgp.11.2.186},
  pmid    = {12611748},
  url     = {https://doi.org/10.1176/appi.ajgp.11.2.186}
}

@article{brodaty2003-12633121,
  author  = {Brodaty, H. and Ames, D. and Snowdon, J. and Woodward, M. and Kirwan, J. and Clarnette, R. and Lee, E. and Lyons, B. and others},
  title   = {{A randomized placebo-controlled trial of risperidone for the treatment of aggression, agitation, and psychosis of dementia}},
  journal = {The Journal of clinical psychiatry},
  year    = {2003},
  doi     = {10.4088/jcp.v64n0205},
  pmid    = {12633121},
  url     = {https://doi.org/10.4088/jcp.v64n0205}
}

@article{akhondzadeh2003-12605619,
  author  = {Akhondzadeh, S. and Noroozian, M. and Mohammadi, M. and Ohadinia, S. and Jamshidi, A. H. and Khani, M.},
  title   = {{Salvia officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomized and placebo-controlled trial}},
  journal = {Journal of clinical pharmacy and therapeutics},
  year    = {2003},
  doi     = {10.1046/j.1365-2710.2003.00463.x},
  pmid    = {12605619},
  url     = {https://doi.org/10.1046/j.1365-2710.2003.00463.x}
}

@article{dejesusmorenomoreno2003-12637119,
  author  = {De Jesus Moreno Moreno, M.},
  title   = {{Cognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial}},
  journal = {Clinical therapeutics},
  year    = {2003},
  doi     = {10.1016/s0149-2918(03)90023-3},
  pmid    = {12637119},
  url     = {https://doi.org/10.1016/s0149-2918(03)90023-3}
}

@article{birks2003-12917900,
  author  = {Birks, J. S. and Harvey, R.},
  title   = {{Donepezil for dementia due to Alzheimer's disease}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2003},
  doi     = {10.1002/14651858.cd001190},
  pmid    = {12917900},
  url     = {https://doi.org/10.1002/14651858.cd001190}
}

@article{higgins2003-12917896,
  author  = {Higgins, J. P. and Flicker, L.},
  title   = {{Lecithin for dementia and cognitive impairment}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2003},
  doi     = {10.1002/14651858.cd001015},
  pmid    = {12917896},
  url     = {https://doi.org/10.1002/14651858.cd001015}
}

@article{wilcock2002-12409683,
  author  = {Wilcock, G. and Möbius, H. J. and Stöffler, A. and {MMM 500 group}},
  title   = {{A double-blind, placebo-controlled multicentre study of memantine in mild to moderate vascular dementia (MMM500)}},
  journal = {International clinical psychopharmacology},
  year    = {2002},
  doi     = {10.1097/00004850-200211000-00005},
  pmid    = {12409683},
  url     = {https://doi.org/10.1097/00004850-200211000-00005}
}

@article{zandi2002-12413371,
  author  = {Zandi, P. P. and Carlson, M. C. and Plassman, B. L. and Welsh-Bohmer, K. A. and Mayer, L. S. and Steffens, D. C. and Breitner, J. C. and {Cache County Memory Study Investigators}},
  title   = {{Hormone replacement therapy and incidence of Alzheimer disease in older women: the Cache County Study}},
  journal = {JAMA},
  year    = {2002},
  doi     = {10.1001/jama.288.17.2123},
  pmid    = {12413371},
  url     = {https://doi.org/10.1001/jama.288.17.2123}
}

@article{forette2002-12374512,
  author  = {Forette, F. and Seux, M. L. and Staessen, J. A. and Thijs, L. and Babarskiene, M. R. and Babeanu, S. and Bossini, A. and Fagard, R. and others},
  title   = {{The prevention of dementia with antihypertensive treatment: new evidence from the Systolic Hypertension in Europe (Syst-Eur) study}},
  journal = {Archives of internal medicine},
  year    = {2002},
  doi     = {10.1001/archinte.162.18.2046},
  pmid    = {12374512},
  url     = {https://doi.org/10.1001/archinte.162.18.2046}
}

@article{zandi2002-12297571,
  author  = {Zandi, P. P. and Anthony, J. C. and Hayden, K. M. and Mehta, K. and Mayer, L. and Breitner, J. C. and {Cache County Study Investigators}},
  title   = {{Reduced incidence of AD with NSAID but not H2 receptor antagonists: the Cache County Study}},
  journal = {Neurology},
  year    = {2002},
  doi     = {10.1212/wnl.59.6.880},
  pmid    = {12297571},
  url     = {https://doi.org/10.1212/wnl.59.6.880}
}

@article{panisset2002-12111446,
  author  = {Panisset, M. and Gauthier, S. and Moessler, H. and Windisch, M. and {Cerebrolysin Study Group}},
  title   = {{Cerebrolysin in Alzheimer's disease: a randomized, double-blind, placebo-controlled trial with a neurotrophic agent}},
  journal = {Journal of neural transmission (Vienna, Austria : 1996)},
  year    = {2002},
  doi     = {10.1007/s007020200092},
  pmid    = {12111446},
  url     = {https://doi.org/10.1007/s007020200092}
}

@article{zhang2002-12181083,
  author  = {Zhang, Z. and Wang, X. and Chen, Q. and Shu, L. and Wang, J. and Shan, G.},
  title   = {{[Clinical efficacy and safety of huperzine Alpha in treatment of mild to moderate Alzheimer disease, a placebo-controlled, double-blind, randomized trial]}},
  journal = {Zhonghua yi xue za zhi},
  year    = {2002},
  pmid    = {12181083}
}

@article{orgogozo2002-12105362,
  author  = {Orgogozo, J. M. and Rigaud, A. S. and Stöffler, A. and Möbius, H. J. and Forette, F.},
  title   = {{Efficacy and safety of memantine in patients with mild to moderate vascular dementia: a randomized, placebo-controlled trial (MMM 300)}},
  journal = {Stroke},
  year    = {2002},
  doi     = {10.1161/01.str.0000020094.08790.49},
  pmid    = {12105362},
  url     = {https://doi.org/10.1161/01.str.0000020094.08790.49}
}

@article{erkinjuntti2002-11965273,
  author  = {Erkinjuntti, T. and Kurz, A. and Gauthier, S. and Bullock, R. and Lilienfeld, S. and Damaraju, C. V.},
  title   = {{Efficacy of galantamine in probable vascular dementia and Alzheimer's disease combined with cerebrovascular disease: a randomised trial}},
  journal = {Lancet (London, England)},
  year    = {2002},
  doi     = {10.1016/s0140-6736(02)08267-3},
  pmid    = {11965273},
  url     = {https://doi.org/10.1016/s0140-6736(02)08267-3}
}

@article{cott2002-12040303,
  author  = {Cott, C. A. and Dawson, P. and Sidani, S. and Wells, D.},
  title   = {{The effects of a walking/talking program on communication, ambulation, and functional status in residents with Alzheimer disease}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2002},
  doi     = {10.1097/00002093-200204000-00005},
  pmid    = {12040303},
  url     = {https://doi.org/10.1097/00002093-200204000-00005}
}

@article{lopez2002-11861686,
  author  = {Lopez, O. L. and Becker, J. T. and Wisniewski, S. and Saxton, J. and Kaufer, D. I. and DeKosky, S. T.},
  title   = {{Cholinesterase inhibitor treatment alters the natural history of Alzheimer's disease}},
  journal = {Journal of neurology, neurosurgery, and psychiatry},
  year    = {2002},
  doi     = {10.1136/jnnp.72.3.310},
  pmid    = {11861686},
  url     = {https://doi.org/10.1136/jnnp.72.3.310}
}

@article{lilienfeld2002-12177686,
  author  = {Lilienfeld, S.},
  title   = {{Galantamine--a novel cholinergic drug with a unique dual mode of action for the treatment of patients with Alzheimer's disease}},
  journal = {CNS drug reviews},
  year    = {2002},
  doi     = {10.1111/j.1527-3458.2002.tb00221.x},
  pmid    = {12177686},
  url     = {https://doi.org/10.1111/j.1527-3458.2002.tb00221.x}
}

@article{carlson2002-11882746,
  author  = {Carlson, M. C. and Tschanz, J. T. and Norton, M. C. and Welsh-Bohmer, K. and Martin, B. K. and Breitner, J. C.},
  title   = {{H2 histamine receptor blockade in the treatment of Alzheimer disease: a randomized, double-blind, placebo-controlled trial of nizatidine}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2002},
  doi     = {10.1097/00002093-200201000-00004},
  pmid    = {11882746},
  url     = {https://doi.org/10.1097/00002093-200201000-00004}
}

@article{sparks2002-12474023,
  author  = {Sparks, D. L. and Connor, D. J. and Browne, P. J. and Lopez, J. E. and Sabbagh, M. N.},
  title   = {{HMG-CoA reductase inhibitors (statins) in the treatment of Alzheimer's disease and why it would be ill-advise to use one that crosses the blood-brain barrier}},
  journal = {The journal of nutrition, health \& aging},
  year    = {2002},
  pmid    = {12474023}
}

@article{harvey2002-12397845,
  author  = {Harvey, Brian Herbert and Meyer, Catharina L. and Manji, Husseini K. and Gallicchio, Vincent S. and Frcpc and others},
  title   = {{Lithium Salts in AIDS and AIDS-Related Dementia}},
  journal = {Psychopharmacology Bulletin},
  year    = {2002},
  doi     = {10.64719/pb.4228},
  pmid    = {12397845},
  url     = {https://doi.org/10.64719/pb.4228}
}

@article{bullock2002-12240787,
  author  = {Bullock, R. and Cameron, A.},
  title   = {{Rivastigmine for the treatment of dementia and visual hallucinations associated with Parkinson's disease: a case series}},
  journal = {Current medical research and opinion},
  year    = {2002},
  doi     = {10.1185/030079902125000813},
  pmid    = {12240787},
  url     = {https://doi.org/10.1185/030079902125000813}
}

@article{tariot2001-11843990,
  author  = {Tariot, P. N. and Cummings, J. L. and Katz, I. R. and Mintzer, J. and Perdomo, C. A. and Schwam, E. M. and Whalen, E.},
  title   = {{A randomized, double-blind, placebo-controlled study of the efficacy and safety of donepezil in patients with Alzheimer's disease in the nursing home setting}},
  journal = {Journal of the American Geriatrics Society},
  year    = {2001},
  doi     = {10.1111/j.1532-5415.2001.49266.x},
  pmid    = {11843990},
  url     = {https://doi.org/10.1111/j.1532-5415.2001.49266.x}
}

@article{raji2001-11573849,
  author  = {Raji, M. A. and Brady, SR.},
  title   = {{Mirtazapine for treatment of depression and comorbidities in Alzheimer disease}},
  journal = {The Annals of pharmacotherapy},
  year    = {2001},
  doi     = {10.1345/aph.10371},
  pmid    = {11573849},
  url     = {https://doi.org/10.1345/aph.10371}
}

@article{mohs2001-11502917,
  author  = {Mohs, R. C. and Doody, R. S. and Morris, J. C. and Ieni, JR. and Rogers, S. L. and Perdomo, C. A. and Pratt, R. D. and {"312" Study Group}},
  title   = {{A 1-year, placebo-controlled preservation of function survival study of donepezil in AD patients}},
  journal = {Neurology},
  year    = {2001},
  doi     = {10.1212/wnl.57.3.481},
  pmid    = {11502917},
  url     = {https://doi.org/10.1212/wnl.57.3.481}
}

@article{feldman2001-11524468,
  author  = {Feldman, H. and Gauthier, S. and Hecker, J. and Vellas, B. and Subbiah, P. and Whalen, E. and {Donepezil MSAD Study Investigators Group}},
  title   = {{A 24-week, randomized, double-blind study of donepezil in moderate to severe Alzheimer's disease}},
  journal = {Neurology},
  year    = {2001},
  doi     = {10.1212/wnl.57.4.613},
  pmid    = {11524468},
  url     = {https://doi.org/10.1212/wnl.57.4.613}
}

@article{hager2001-11395173,
  author  = {Hager, K. and Marahrens, A. and Kenklies, M. and Riederer, P. and Münch, G.},
  title   = {{Alpha-lipoic acid as a new treatment option for Alzheimer [corrected] type dementia}},
  journal = {Archives of gerontology and geriatrics},
  year    = {2001},
  doi     = {10.1016/s0167-4943(01)00104-2},
  pmid    = {11395173},
  url     = {https://doi.org/10.1016/s0167-4943(01)00104-2}
}

@article{fassbender2001-11296263,
  author  = {Fassbender, K. and Simons, M. and Bergmann, C. and Stroick, M. and Lutjohann, D. and Keller, P. and Runz, H. and Kuhl, S. and others},
  title   = {{Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2001},
  doi     = {10.1073/pnas.081620098},
  pmid    = {11296263},
  url     = {https://doi.org/10.1073/pnas.081620098}
}

@article{farlow2001-11255445,
  author  = {Farlow, M. R. and Hake, A. and Messina, J. and Hartman, R. and Veach, J. and Anand, R.},
  title   = {{Response of patients with Alzheimer disease to rivastigmine treatment is predicted by the rate of disease progression}},
  journal = {Archives of neurology},
  year    = {2001},
  doi     = {10.1001/archneur.58.3.417},
  pmid    = {11255445},
  url     = {https://doi.org/10.1001/archneur.58.3.417}
}

@article{olin2001-11739066,
  author  = {Olin, J. T. and Fox, L. S. and Pawluczyk, S. and Taggart, N. A. and Schneider, L. S.},
  title   = {{A pilot randomized trial of carbamazepine for behavioral symptoms in treatment-resistant outpatients with Alzheimer disease}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2001},
  doi     = {10.1176/appi.ajgp.9.4.400},
  pmid    = {11739066},
  url     = {https://doi.org/10.1176/appi.ajgp.9.4.400}
}

@article{coelho2001-11405996,
  author  = {Coelho, F. and Birks, J.},
  title   = {{Physostigmine for Alzheimer's disease}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2001},
  doi     = {10.1002/14651858.cd001499},
  pmid    = {11405996},
  url     = {https://doi.org/10.1002/14651858.cd001499}
}

@article{flicker2001-11405971,
  author  = {Flicker, L. and Grimley Evans, G.},
  title   = {{Piracetam for dementia or cognitive impairment}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2001},
  doi     = {10.1002/14651858.cd001011},
  pmid    = {11405971},
  url     = {https://doi.org/10.1002/14651858.cd001011}
}

@article{morgan2000-11140686,
  author  = {Morgan, D. and Diamond, D. M. and Gottschall, P. E. and Ugen, K. E. and Dickey, C. and Hardy, J. and Duff, K. and Jantzen, P. and others},
  title   = {{A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease}},
  journal = {Nature},
  year    = {2000},
  doi     = {10.1038/35050116},
  pmid    = {11140686},
  url     = {https://doi.org/10.1038/35050116}
}

@article{wilcock2000-11110737,
  author  = {Wilcock, G. K. and Lilienfeld, S. and Gaens, E.},
  title   = {{Efficacy and safety of galantamine in patients with mild to moderate Alzheimer's disease: multicentre randomised controlled trial. Galantamine International-1 Study Group}},
  journal = {BMJ (Clinical research ed.)},
  year    = {2000},
  doi     = {10.1136/bmj.321.7274.1445},
  pmid    = {11110737},
  url     = {https://doi.org/10.1136/bmj.321.7274.1445}
}

@article{mckeith2000-11145488,
  author  = {McKeith, I. and Del Ser, T. and Spano, P. and Emre, M. and Wesnes, K. and Anand, R. and Cicin-Sain, A. and Ferrara, R. and others},
  title   = {{Efficacy of rivastigmine in dementia with Lewy bodies: a randomised, double-blind, placebo-controlled international study}},
  journal = {Lancet (London, England)},
  year    = {2000},
  doi     = {10.1016/s0140-6736(00)03399-7},
  pmid    = {11145488},
  url     = {https://doi.org/10.1016/s0140-6736(00)03399-7}
}

@article{homma2000-11044775,
  author  = {Homma, A. and Takeda, M. and Imai, Y. and Udaka, F. and Hasegawa, K. and Kameyama, M. and Nishimura, T.},
  title   = {{Clinical efficacy and safety of donepezil on cognitive and global function in patients with Alzheimer's disease. A 24-week, multicenter, double-blind, placebo-controlled study in Japan. E2020 Study Group}},
  journal = {Dementia and geriatric cognitive disorders},
  year    = {2000},
  doi     = {10.1159/000017259},
  pmid    = {11044775},
  url     = {https://doi.org/10.1159/000017259}
}

@article{street2000-11015815,
  author  = {Street, J. S. and Clark, W. S. and Gannon, K. S. and Cummings, J. L. and Bymaster, F. P. and Tamura, R. N. and Mitan, S. J. and Kadam, D. L. and others},
  title   = {{Olanzapine treatment of psychotic and behavioral symptoms in patients with Alzheimer disease in nursing care facilities: a double-blind, randomized, placebo-controlled trial. The HGEU Study Group}},
  journal = {Archives of general psychiatry},
  year    = {2000},
  doi     = {10.1001/archpsyc.57.10.968},
  pmid    = {11015815},
  url     = {https://doi.org/10.1001/archpsyc.57.10.968}
}

@article{alvarez2000-11196347,
  author  = {Alvarez, X. A. and Pichel, V. and Pérez, P. and Laredo, M. and Corzo, D. and Zas, R. and Fernández-Novoa, L. and Sempere, J. M. and others},
  title   = {{Double-blind, randomized, placebo-controlled pilot study with anapsos in senile dementia: effects on cognition, brain bioelectrical activity and cerebral hemodynamics}},
  journal = {Methods and findings in experimental and clinical pharmacology},
  year    = {2000},
  doi     = {10.1358/mf.2000.22.7.802270},
  pmid    = {11196347},
  url     = {https://doi.org/10.1358/mf.2000.22.7.802270}
}

@article{cohenmansfield2000-10989165,
  author  = {Cohen-Mansfield, J. and Garfinkel, D. and Lipson, S.},
  title   = {{Melatonin for treatment of sundowning in elderly persons with dementia - a preliminary study}},
  journal = {Archives of gerontology and geriatrics},
  year    = {2000},
  doi     = {10.1016/s0167-4943(00)00068-6},
  pmid    = {10989165},
  url     = {https://doi.org/10.1016/s0167-4943(00)00068-6}
}

@article{lebars2000-10867450,
  author  = {Le Bars, P. L. and Kieser, M. and Itil, K. Z.},
  title   = {{A 26-week analysis of a double-blind, placebo-controlled trial of the ginkgo biloba extract EGb 761 in dementia}},
  journal = {Dementia and geriatric cognitive disorders},
  year    = {2000},
  doi     = {10.1159/000017242},
  pmid    = {10867450},
  url     = {https://doi.org/10.1159/000017242}
}

@article{emeriau2000-10945510,
  author  = {Emeriau, J. P. and Lehert, P. and Mosnier, M.},
  title   = {{Efficacy of naftidrofuryl in patients with vascular or mixed dementia: results of a multicenter, double-blind trial}},
  journal = {Clinical therapeutics},
  year    = {2000},
  doi     = {10.1016/s0149-2918(00)80056-9},
  pmid    = {10945510},
  url     = {https://doi.org/10.1016/s0149-2918(00)80056-9}
}

@article{raskind2000-10881250,
  author  = {Raskind, M. A. and Peskind, E. R. and Wessel, T. and Yuan, W.},
  title   = {{Galantamine in AD: A 6-month randomized, placebo-controlled trial with a 6-month extension. The Galantamine USA-1 Study Group}},
  journal = {Neurology},
  year    = {2000},
  doi     = {10.1212/wnl.54.12.2261},
  pmid    = {10881250},
  url     = {https://doi.org/10.1212/wnl.54.12.2261}
}

@article{rogers2000-10793322,
  author  = {Rogers, S. L. and Doody, R. S. and Pratt, R. D. and Ieni, JR.},
  title   = {{Long-term efficacy and safety of donepezil in the treatment of Alzheimer's disease: final analysis of a US multicentre open-label study}},
  journal = {European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology},
  year    = {2000},
  doi     = {10.1016/s0924-977x(00)00067-5},
  pmid    = {10793322},
  url     = {https://doi.org/10.1016/s0924-977x(00)00067-5}
}

@article{mulnard2000-10697060,
  author  = {Mulnard, R. A. and Cotman, C. W. and Kawas, C. and van Dyck, C. H. and Sano, M. and Doody, R. and Koss, E. and Pfeiffer, E. and others},
  title   = {{Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: a randomized controlled trial. Alzheimer's Disease Cooperative Study}},
  journal = {JAMA},
  year    = {2000},
  doi     = {10.1001/jama.283.8.1007},
  pmid    = {10697060},
  url     = {https://doi.org/10.1001/jama.283.8.1007}
}

@article{vandyck2000-10665618,
  author  = {van Dyck, C. H. and Newhouse, P. and Falk, W. E. and Mattes, J. A.},
  title   = {{Extended-release physostigmine in Alzheimer disease: a multicenter, double-blind, 12-week study with dose enrichment. Physostigmine Study Group}},
  journal = {Archives of general psychiatry},
  year    = {2000},
  doi     = {10.1001/archpsyc.57.2.157},
  pmid    = {10665618},
  url     = {https://doi.org/10.1001/archpsyc.57.2.157}
}

@article{giacobini2000-10850724,
  author  = {Giacobini, E.},
  title   = {{Cholinesterase inhibitor therapy stabilizes symptoms of Alzheimer disease}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2000},
  doi     = {10.1097/00002093-200000001-00002},
  pmid    = {10850724},
  url     = {https://doi.org/10.1097/00002093-200000001-00002}
}

@article{henderson2000-10668686,
  author  = {Henderson, V. W. and Paganini-Hill, A. and Miller, B. L. and Elble, R. J. and Reyes, P. F. and Shoupe, D. and McCleary, C. A. and Klein, R. A. and others},
  title   = {{Estrogen for Alzheimer's disease in women: randomized, double-blind, placebo-controlled trial}},
  journal = {Neurology},
  year    = {2000},
  doi     = {10.1212/wnl.54.2.295},
  pmid    = {10668686},
  url     = {https://doi.org/10.1212/wnl.54.2.295}
}

@article{higgins2000-11034695,
  author  = {Higgins, J. P. and Flicker, L.},
  title   = {{Lecithin for dementia and cognitive impairment}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2000},
  doi     = {10.1002/14651858.cd001015},
  pmid    = {11034695},
  url     = {https://doi.org/10.1002/14651858.cd001015}
}

@article{birks2000-11034705,
  author  = {Birks, J. and Grimley Evans, J. and Iakovidou, V. and Tsolaki, M.},
  title   = {{Rivastigmine for Alzheimer's disease}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2000},
  doi     = {10.1002/14651858.cd001191},
  pmid    = {11034705},
  url     = {https://doi.org/10.1002/14651858.cd001191}
}

@article{alvarez1999-10669911,
  author  = {Alvarez, X. A. and Mouzo, R. and Pichel, V. and Pérez, P. and Laredo, M. and Fernández-Novoa, L. and Corzo, L. and Zas, R. and others},
  title   = {{Double-blind placebo-controlled study with citicoline in APOE genotyped Alzheimer's disease patients. Effects on cognitive performance, brain bioelectrical activity and cerebral perfusion}},
  journal = {Methods and findings in experimental and clinical pharmacology},
  year    = {1999},
  doi     = {10.1358/mf.1999.21.9.795632},
  pmid    = {10669911},
  url     = {https://doi.org/10.1358/mf.1999.21.9.795632}
}

@article{kittner1999-10609697,
  author  = {Kittner, B.},
  title   = {{Clinical trials of propentofylline in vascular dementia. European/Canadian Propentofylline Study Group}},
  journal = {Alzheimer disease and associated disorders},
  year    = {1999},
  pmid    = {10609697}
}

@article{dedeyn1999-10496251,
  author  = {De Deyn, P. P. and Rabheru, K. and Rasmussen, A. and Bocksberger, J. P. and Dautzenberg, P. L. and Eriksson, S. and Lawlor, B. A.},
  title   = {{A randomized trial of risperidone, placebo, and haloperidol for behavioral symptoms of dementia}},
  journal = {Neurology},
  year    = {1999},
  doi     = {10.1212/wnl.53.5.946},
  pmid    = {10496251},
  url     = {https://doi.org/10.1212/wnl.53.5.946}
}

@article{lyketsos1999-10440971,
  author  = {Lyketsos, C. G. and Lindell Veiel, L. and Baker, A. and Steele, C.},
  title   = {{A randomized, controlled trial of bright light therapy for agitated behaviors in dementia patients residing in long-term care}},
  journal = {International journal of geriatric psychiatry},
  year    = {1999},
  doi     = {10.1002/(sici)1099-1166(199907)14:7<520::aid-gps983>3.0.co;2-m},
  pmid    = {10440971},
  url     = {https://doi.org/10.1002/(sici)1099-1166(199907)14:7<520::aid-gps983>3.0.co;2-m}
}

@article{xu1999-10678137,
  author  = {Xu, S. S. and Cai, Z. Y. and Qu, Z. W. and Yang, R. M. and Cai, Y. L. and Wang, G. Q. and Su, X. Q. and Zhong, X. S. and others},
  title   = {{Huperzine-A in capsules and tablets for treating patients with Alzheimer disease}},
  journal = {Zhongguo yao li xue bao = Acta pharmacologica Sinica},
  year    = {1999},
  pmid    = {10678137}
}

@article{parsons1999-10465680,
  author  = {Parsons, C. G. and Danysz, W. and Quack, G.},
  title   = {{Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist--a review of preclinical data}},
  journal = {Neuropharmacology},
  year    = {1999},
  doi     = {10.1016/s0028-3908(99)00019-2},
  pmid    = {10465680},
  url     = {https://doi.org/10.1016/s0028-3908(99)00019-2}
}

@article{moller1999-10463377,
  author  = {Möller, H. J. and Hampel, H. and Hegerl, U. and Schmitt, W. and Walter, K.},
  title   = {{Double-blind, randomized, placebo-controlled clinical trial on the efficacy and tolerability of a physostigmine patch in patients with senile dementia of the Alzheimer type}},
  journal = {Pharmacopsychiatry},
  year    = {1999},
  doi     = {10.1055/s-2007-979202},
  pmid    = {10463377},
  url     = {https://doi.org/10.1055/s-2007-979202}
}

@article{filip1999-10354658,
  author  = {Filip, V. and Kolibás, E.},
  title   = {{Selegiline in the treatment of Alzheimer's disease: a long-term randomized placebo-controlled trial. Czech and Slovak Senile Dementia of Alzheimer Type Study Group}},
  journal = {Journal of psychiatry \& neuroscience : JPN},
  year    = {1999},
  pmid    = {10354658}
}

@article{burns1999-10325453,
  author  = {Burns, A. and Rossor, M. and Hecker, J. and Gauthier, S. and Petit, H. and Möller, H. J. and Rogers, S. L. and Friedhoff, L. T.},
  title   = {{The effects of donepezil in Alzheimer's disease - results from a multinational trial}},
  journal = {Dementia and geriatric cognitive disorders},
  year    = {1999},
  doi     = {10.1159/000017126},
  pmid    = {10325453},
  url     = {https://doi.org/10.1159/000017126}
}

@article{katz1999-10084637,
  author  = {Katz, I. R. and Jeste, D. V. and Mintzer, J. E. and Clyde, C. and Napolitano, J. and Brecher, M.},
  title   = {{Comparison of risperidone and placebo for psychosis and behavioral disturbances associated with dementia: a randomized, double-blind trial. Risperidone Study Group}},
  journal = {The Journal of clinical psychiatry},
  year    = {1999},
  doi     = {10.4088/jcp.v60n0207},
  pmid    = {10084637},
  url     = {https://doi.org/10.4088/jcp.v60n0207}
}

@article{oken1998-9823823,
  author  = {Oken, B. S. and Storzbach, D. M. and Kaye, J. A.},
  title   = {{The efficacy of Ginkgo biloba on cognitive function in Alzheimer disease}},
  journal = {Archives of neurology},
  year    = {1998},
  doi     = {10.1001/archneur.55.11.1409},
  pmid    = {9823823},
  url     = {https://doi.org/10.1001/archneur.55.11.1409}
}

@article{forette1998-9802273,
  author  = {Forette, F. and Seux, M. L. and Staessen, J. A. and Thijs, L. and Birkenhäger, W. H. and Babarskiene, M. R. and Babeanu, S. and Bossini, A. and others},
  title   = {{Prevention of dementia in randomised double-blind placebo-controlled Systolic Hypertension in Europe (Syst-Eur) trial}},
  journal = {Lancet (London, England)},
  year    = {1998},
  doi     = {10.1016/s0140-6736(98)03086-4},
  pmid    = {9802273},
  url     = {https://doi.org/10.1016/s0140-6736(98)03086-4}
}

@article{marcotte1998-9858083,
  author  = {Marcotte, D.},
  title   = {{Use of topiramate, a new anti-epileptic as a mood stabilizer}},
  journal = {Journal of affective disorders},
  year    = {1998},
  doi     = {10.1016/s0165-0327(98)00110-4},
  pmid    = {9858083},
  url     = {https://doi.org/10.1016/s0165-0327(98)00110-4}
}

@article{rogers1998-9588436,
  author  = {Rogers, S. L. and Doody, R. S. and Mohs, R. C. and Friedhoff, L. T.},
  title   = {{Donepezil improves cognition and global function in Alzheimer disease: a 15-week, double-blind, placebo-controlled study. Donepezil Study Group}},
  journal = {Archives of internal medicine},
  year    = {1998},
  doi     = {10.1001/archinte.158.9.1021},
  pmid    = {9588436},
  url     = {https://doi.org/10.1001/archinte.158.9.1021}
}

@article{morris1998-9595967,
  author  = {Morris, J. C. and Cyrus, P. A. and Orazem, J. and Mas, J. and Bieber, F. and Ruzicka, B. B. and Gulanski, B.},
  title   = {{Metrifonate benefits cognitive, behavioral, and global function in patients with Alzheimer's disease}},
  journal = {Neurology},
  year    = {1998},
  doi     = {10.1212/wnl.50.5.1222},
  pmid    = {9595967},
  url     = {https://doi.org/10.1212/wnl.50.5.1222}
}

@article{baldereschi1998-9566385,
  author  = {Baldereschi, M. and Di Carlo, A. and Lepore, V. and Bracco, L. and Maggi, S. and Grigoletto, F. and Scarlato, G. and Amaducci, L.},
  title   = {{Estrogen-replacement therapy and Alzheimer's disease in the Italian Longitudinal Study on Aging}},
  journal = {Neurology},
  year    = {1998},
  doi     = {10.1212/wnl.50.4.996},
  pmid    = {9566385},
  url     = {https://doi.org/10.1212/wnl.50.4.996}
}

@article{rogers1998-9452942,
  author  = {Rogers, S. L. and Friedhoff, L. T.},
  title   = {{Long-term efficacy and safety of donepezil in the treatment of Alzheimer's disease: an interim analysis of the results of a US multicentre open label extension study}},
  journal = {European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology},
  year    = {1998},
  doi     = {10.1016/s0924-977x(97)00079-5},
  pmid    = {9452942},
  url     = {https://doi.org/10.1016/s0924-977x(97)00079-5}
}

@article{rogers1998-9443470,
  author  = {Rogers, S. L. and Farlow, M. R. and Doody, R. S. and Mohs, R. and Friedhoff, L. T.},
  title   = {{A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease. Donepezil Study Group}},
  journal = {Neurology},
  year    = {1998},
  doi     = {10.1212/wnl.50.1.136},
  pmid    = {9443470},
  url     = {https://doi.org/10.1212/wnl.50.1.136}
}

@article{mielke1998-9769027,
  author  = {Mielke, R. and Möller, H. J. and Erkinjuntti, T. and Rosenkranz, B. and Rother, M. and Kittner, B.},
  title   = {{Propentofylline in the treatment of vascular dementia and Alzheimer-type dementia: overview of phase I and phase II clinical trials}},
  journal = {Alzheimer disease and associated disorders},
  year    = {1998},
  pmid    = {9769027}
}

@article{lebars1997-9343463,
  author  = {Le Bars, P. L. and Katz, M. M. and Berman, N. and Itil, T. M. and Freedman, A. M. and Schatzberg, A. F.},
  title   = {{A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group}},
  journal = {JAMA},
  year    = {1997},
  doi     = {10.1001/jama.278.16.1327},
  pmid    = {9343463},
  url     = {https://doi.org/10.1001/jama.278.16.1327}
}

@article{raskind1997-9236571,
  author  = {Raskind, M. A. and Sadowsky, C. H. and Sigmund, W. R. and Beitler, P. J. and Auster, S. B.},
  title   = {{Effect of tacrine on language, praxis, and noncognitive behavioral problems in Alzheimer disease}},
  journal = {Archives of neurology},
  year    = {1997},
  doi     = {10.1001/archneur.1997.00550190026010},
  pmid    = {9236571},
  url     = {https://doi.org/10.1001/archneur.1997.00550190026010}
}

@article{sano1997-9110909,
  author  = {Sano, Mary and Ernesto, Christopher and Thomas, Ronald G. and Klauber, Melville R. and Schafer, Kimberly A and Grundman, Michael and Woodbury, Peter and Growdon, John H. and Cotman, Carl W. and Pfeiffer, Eric A. and Schneider, Lon S. and Thal, Leon J.},
  title   = {{A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study}},
  journal = {New England Journal of Medicine},
  year    = {1997},
  doi     = {10.1056/nejm199704243361704},
  pmid    = {9110909},
  url     = {https://doi.org/10.1056/nejm199704243361704}
}

@article{bodick1997-9109749,
  author  = {Bodick, N. C. and Offen, W. W. and Levey, A. I. and Cutler, N. R. and Gauthier, S. G. and Satlin, A. and Shannon, H. E. and Tollefson, G. D. and others},
  title   = {{Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease}},
  journal = {Archives of neurology},
  year    = {1997},
  doi     = {10.1001/archneur.1997.00550160091022},
  pmid    = {9109749},
  url     = {https://doi.org/10.1001/archneur.1997.00550160091022}
}

@article{mittelman1996-8940320,
  author  = {Mittelman, M. S. and Ferris, S. H. and Shulman, E. and Steinberg, G. and Levin, B.},
  title   = {{A family intervention to delay nursing home placement of patients with Alzheimer disease. A randomized controlled trial}},
  journal = {JAMA},
  year    = {1996},
  doi     = {10.1001/jama.1996.03540210033030},
  pmid    = {8940320},
  url     = {https://doi.org/10.1001/jama.1996.03540210033030}
}

@article{thal1996-8960716,
  author  = {Thal, L. J. and Schwartz, G. and Sano, M. and Weiner, M. and Knopman, D. and Harrell, L. and Bodenheimer, S. and Rossor, M. and others},
  title   = {{A multicenter double-blind study of controlled-release physostigmine for the treatment of symptoms secondary to Alzheimer's disease. Physostigmine Study Group}},
  journal = {Neurology},
  year    = {1996},
  doi     = {10.1212/wnl.47.6.1389},
  pmid    = {8960716},
  url     = {https://doi.org/10.1212/wnl.47.6.1389}
}

@article{haase1996-8974721,
  author  = {Haase, J. and Halama, P. and Hörr, R.},
  title   = {{[Effectiveness of brief infusions with Ginkgo biloba Special Extract EGb 761 in dementia of the vascular and Alzheimer type]}},
  journal = {Zeitschrift fur Gerontologie und Geriatrie},
  year    = {1996},
  pmid    = {8974721}
}

@article{kaufer1996-8679057,
  author  = {Kaufer, D. I. and Cummings, J. L. and Christine, D.},
  title   = {{Effect of tacrine on behavioral symptoms in Alzheimer's disease: an open-label study}},
  journal = {Journal of geriatric psychiatry and neurology},
  year    = {1996},
  doi     = {10.1177/089198879600900101},
  pmid    = {8679057},
  url     = {https://doi.org/10.1177/089198879600900101}
}

@article{sano1996-8876776,
  author  = {Sano, M. and Ernesto, C. and Klauber, M. R. and Schafer, K. and Woodbury, P. and Thomas, R. and Grundman, M. and Growdon, J. and others},
  title   = {{Rationale and design of a multicenter study of selegiline and alpha-tocopherol in the treatment of Alzheimer disease using novel clinical outcomes. Alzheimer's Disease Cooperative Study}},
  journal = {Alzheimer disease and associated disorders},
  year    = {1996},
  doi     = {10.1097/00002093-199601030-00004},
  pmid    = {8876776},
  url     = {https://doi.org/10.1097/00002093-199601030-00004}
}

@article{ohkura1995-7606287,
  author  = {Ohkura, T. and Isse, K. and Akazawa, K. and Hamamoto, M. and Yaoi, Y. and Hagino, N.},
  title   = {{Long-term estrogen replacement therapy in female patients with dementia of the Alzheimer type: 7 case reports}},
  journal = {Dementia (Basel, Switzerland)},
  year    = {1995},
  doi     = {10.1159/000106929},
  pmid    = {7606287},
  url     = {https://doi.org/10.1159/000106929}
}

@article{ohkura1994-8528351,
  author  = {Ohkura, T. and Isse, K. and Akazawa, K. and Hamamoto, M. and Yaoi, Y. and Hagino, N.},
  title   = {{Evaluation of estrogen treatment in female patients with dementia of the Alzheimer type}},
  journal = {Endocrine journal},
  year    = {1994},
  doi     = {10.1507/endocrj.41.361},
  pmid    = {8528351},
  url     = {https://doi.org/10.1507/endocrj.41.361}
}

@article{bergamasco1994-7988944,
  author  = {Bergamasco, B. and Scarzella, L. and La Commare, P.},
  title   = {{Idebenone, a new drug in the treatment of cognitive impairment in patients with dementia of the Alzheimer type}},
  journal = {Functional neurology},
  year    = {1994},
  pmid    = {7988944}
}

@article{popa1994-18649860,
  author  = {Popa, R. and Schneider, F. and Mihalas, G. and Stefaniga, P. and Mihalas, I. G. and Maties, R. and Mateescu, R.},
  title   = {{Antagonic-stress superiority versus meclofenoxate in gerontopsychiatry (alzheimer type dementia)}},
  journal = {Archives of gerontology and geriatrics},
  year    = {1994},
  doi     = {10.1016/s0167-4943(05)80065-2},
  pmid    = {18649860},
  url     = {https://doi.org/10.1016/s0167-4943(05)80065-2}
}

@article{burke1993-8227897,
  author  = {Burke, W. J. and Roccaforte, W. H. and Wengel, S. P. and Bayer, B. L. and Ranno, A. E. and Willcockson, N. K.},
  title   = {{L-deprenyl in the treatment of mild dementia of the Alzheimer type: results of a 15-month trial}},
  journal = {Journal of the American Geriatrics Society},
  year    = {1993},
  doi     = {10.1111/j.1532-5415.1993.tb07306.x},
  pmid    = {8227897},
  url     = {https://doi.org/10.1111/j.1532-5415.1993.tb07306.x}
}

@article{fedele1993-7716695,
  author  = {Fedele, D. J. and Jones, J. A. and Volicer, L. and Herz, L. R. and Oppenheim, F. G.},
  title   = {{Effects of medication on parotid salivary flow rates in an individual with dementia of the Alzheimer type}},
  journal = {Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry},
  year    = {1993},
  doi     = {10.1111/j.1754-4505.1993.tb01499.x},
  pmid    = {7716695},
  url     = {https://doi.org/10.1111/j.1754-4505.1993.tb01499.x}
}

@article{burke1993-8463521,
  author  = {Burke, W. J. and Ranno, A. E. and Roccaforte, W. H. and Wengel, S. P. and Bayer, B. L. and Willcockson, N. K.},
  title   = {{L-deprenyl in the treatment of mild dementia of the Alzheimer type: preliminary results}},
  journal = {Journal of the American Geriatrics Society},
  year    = {1993},
  doi     = {10.1111/j.1532-5415.1993.tb06942.x},
  pmid    = {8463521},
  url     = {https://doi.org/10.1111/j.1532-5415.1993.tb06942.x}
}

@article{dysken1992-1634705,
  author  = {Dysken, M. W. and Mendels, J. and LeWitt, P. and Reisberg, B. and Pomara, N. and Wood, J. and Skare, S. and Fakouhi, J. D. and others},
  title   = {{Milacemide: a placebo-controlled study in senile dementia of the Alzheimer type}},
  journal = {Journal of the American Geriatrics Society},
  year    = {1992},
  doi     = {10.1111/j.1532-5415.1992.tb02019.x},
  pmid    = {1634705},
  url     = {https://doi.org/10.1111/j.1532-5415.1992.tb02019.x}
}

@article{finali1992-1592575,
  author  = {Finali, G. and Piccirilli, M. and Oliani, C. and Piccinin, G. L.},
  title   = {{Alzheimer-type dementia and verbal memory performances: influence of selegiline therapy}},
  journal = {Italian journal of neurological sciences},
  year    = {1992},
  doi     = {10.1007/bf02226963},
  pmid    = {1592575},
  url     = {https://doi.org/10.1007/bf02226963}
}

@article{villardita1992-1603291,
  author  = {Villardita, C. and Grioli, S. and Lomeo, C. and Cattaneo, C. and Parini, J.},
  title   = {{Clinical studies with oxiracetam in patients with dementia of Alzheimer type and multi-infarct dementia of mild to moderate degree}},
  journal = {Neuropsychobiology},
  year    = {1992},
  doi     = {10.1159/000118805},
  pmid    = {1603291},
  url     = {https://doi.org/10.1159/000118805}
}

@article{crappermclachlan1991-1674295,
  author  = {Crapper McLachlan, D. R. and Dalton, A. J. and Kruck, T. P. and Bell, M. Y. and Smith, W. L. and Kalow, W. and Andrews, D. F.},
  title   = {{Intramuscular desferrioxamine in patients with Alzheimer's disease}},
  journal = {Lancet (London, England)},
  year    = {1991},
  doi     = {10.1016/0140-6736(91)92978-b},
  pmid    = {1674295},
  url     = {https://doi.org/10.1016/0140-6736(91)92978-b}
}

@article{monteverde1990-2121360,
  author  = {Monteverde, A. and Gnemmi, P. and Rossi, F. and Finali, G. C.},
  title   = {{Selegiline in the treatment of mild to moderate Alzheimer-type dementia}},
  journal = {Clinical therapeutics},
  year    = {1990},
  pmid    = {2121360}
}

@article{rai1990-2178869,
  author  = {Rai, G. and Wright, G. and Scott, L. and Beston, B. and Rest, J. and Exton-Smith, A. N.},
  title   = {{Double-blind, placebo controlled study of acetyl-l-carnitine in patients with Alzheimer's dementia}},
  journal = {Current medical research and opinion},
  year    = {1990},
  doi     = {10.1185/03007999009112690},
  pmid    = {2178869},
  url     = {https://doi.org/10.1185/03007999009112690}
}

@article{risse1986-2870097,
  author  = {Risse, S. C. and Barnes, R.},
  title   = {{Pharmacologic treatment of agitation associated with dementia}},
  journal = {Journal of the American Geriatrics Society},
  year    = {1986},
  doi     = {10.1111/j.1532-5415.1986.tb04320.x},
  pmid    = {2870097},
  url     = {https://doi.org/10.1111/j.1532-5415.1986.tb04320.x}
}

@article{fleischhacker1986-3517967,
  author  = {Fleischhacker, W. W. and Buchgeher, A. and Schubert, H.},
  title   = {{Memantine in the treatment of senile dementia of the Alzheimer type}},
  journal = {Progress in neuro-psychopharmacology \& biological psychiatry},
  year    = {1986},
  doi     = {10.1016/0278-5846(86)90047-3},
  pmid    = {3517967},
  url     = {https://doi.org/10.1016/0278-5846(86)90047-3}
}