% alzhub.org topic: mitochondrial % Source: https://alzhub.org/topic/mitochondrial % 275 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{garciasimili2026-9dc141d1, author = {Garcia Simili, O. A. and Magno de Carvalho, G. and Santana Dias Simões, R. and Rucco Penteado Detregiachi, C. and de Souza Bastos Mazuqueli Pereira, E. and Cavallari Strozze Catharin, V. M. and da Silva, G. A. and Miola, V. B. and others}, title = {{Pantethine and Neurodegeneration: A Coenzyme A-Centered Framework Linking Metabolism, Neuroinflammation, and Mitochondrial Dysfunction}}, journal = {Preprints.org}, year = {2026}, doi = {10.20944/preprints202607.2061.v5}, url = {https://doi.org/10.20944/preprints202607.2061.v5} } @article{li2026-7bf20a60, author = {Li, Y. and ploumi, C. and Volbracht, C. and Tian, W. and Kalogeraki, N. and Kitopoulou, K. and Navarro, C. C. and Li, Z. and others}, title = {{BNIP3L/NIX-mediated mitophagy limits Alzheimer’s disease pathology and preserves neuronal function}}, journal = {bioRxiv}, year = {2026}, doi = {10.64898/2026.10.18.759942}, url = {https://doi.org/10.64898/2026.10.18.759942} } @article{navarro2026-b65d2812, author = {Navarro, M. and Aquino, J. and Shi, K. and Lin, H. and Monfared, V. and Garcia, J. C. and Seylani, A. and Komędera, M. and others}, title = {{Convergent Mitochondrial and Oxidative Stress Signatures in Spaceflight and Tauopathy: A Comparative Multi-Omics Reanalysis in Drosophila melanogaster}}, journal = {bioRxiv}, year = {2026}, doi = {10.64898/2026.10.16.759726}, url = {https://doi.org/10.64898/2026.10.16.759726} } @article{wang2026-13e8938d, author = {Wang, F. and Li, P. and Huang, R. S.}, title = {{Constraint Based Metabolic Modeling Identifies Robust Biomarkers and Therapeutic Target Combinations in Alzheimer Disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11324647/v1}, url = {https://doi.org/10.21203/rs.3.rs-11324647/v1} } @article{yu2026-37f5ced5, author = {Yu, H. and Yang, H. and Shi, J. and Dong, W. and Wang, Z. and Meng, M. and Wang, L. and others}, title = {{PDE4D inhibition activates cAMP-PKA signaling to preserve mitochondrial homeostasis and prevent neuronal necroptosis in Alzheimer's disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11070692/v1}, url = {https://doi.org/10.21203/rs.3.rs-11070692/v1} } @article{kotredes2026-6da14e5f, author = {Kotredes, K. P. and Pandey, R. S. and Reagan, A. M. and Sarica, Z. and O'Rourke, R. and Herrick, S. and Davis, A. and Garceau, D. and others}, title = {{MTHFR*677C>T produces distinct prodromal disease signatures in a mouse model of late-onset Alzheimer’s disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11166891/v1}, url = {https://doi.org/10.21203/rs.3.rs-11166891/v1} } @article{wang2026-88551104, author = {Wang, H. and Wang, Y. and Xie, Y. and Liu, P. and Zhao, M. and Hao, R. and Zhang, H. and Li, P.}, title = {{Spermine inhibits ferroptosis in vascular dementia rats by intervening Nrf2/SLC7A11/GPX4 expression in chondriosome}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11156074/v1}, url = {https://doi.org/10.21203/rs.3.rs-11156074/v1} } @article{elsalamony2026-a10c51b4, author = {EL-Salamony, G. I. and Mohamed, R. H. and Saad, R. A. and Tarek, M. and Fawzy, N. M. and Elnahas, E. M.}, title = {{Neuroprotective Role of Vitamin D Against LPS-Induced Cognitive Deficits in Rats: Targeting Hippocampal PERK-ATF4-CHOP-Mediated ER Stress and Calcium Dyshomeostasis}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10413434/v1}, url = {https://doi.org/10.21203/rs.3.rs-10413434/v1} } @article{moallem2026-2631138c, author = {Moallem, E. Z. and Bruntz, R. C. and Cox, M. F. and Bytyqi, L. and Roberts, T. K. and Patel, S. P. and Macheda, T. and Roberts, K. N. and others}, title = {{Closed-head injury produces a delayed, region-specific defect in glucose-carbon routing at the pyruvate branchpoint in APP/PS1 KI mice}}, journal = {bioRxiv}, year = {2026}, doi = {10.64898/2026.09.29.755475}, url = {https://doi.org/10.64898/2026.09.29.755475} } @article{grant2026-2682dc91, author = {Grant, R. A. and Park, L. H. E. and Wahl, D. and LaRocca, T. J.}, title = {{Apigenin Improves Healthspan and Protects Against Alzheimer’s Disease-Associated Proteotoxicity in C. elegans}}, journal = {bioRxiv}, year = {2026}, doi = {10.64898/2026.09.23.753917}, url = {https://doi.org/10.64898/2026.09.23.753917} } @article{mathews2026-7aad1a5f, author = {Mathews, R. and Bouyadjera, S. B. and Donegan, J. J. and Havird, J. C.}, title = {{Mitochondrial DNA copy number in neurodegenerative diseases: a global meta-analysis of 156 comparisons across 76 studies}}, journal = {bioRxiv}, year = {2026}, doi = {10.64898/2026.08.25.747144}, url = {https://doi.org/10.64898/2026.08.25.747144} } @article{li2026-314444c7, author = {Li, J. and Li, Y. and Bhat, A. and Zheng, M. and Zhang, Q.}, title = {{Low-dose lithium prevents age-dependent metabolic stress–driven alzheimer’s disease–like pathology through restoration of the NAMPT–NAD⁺–SIRT1–AMPK–TFEB metabolic resilience network}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10738655/v1}, url = {https://doi.org/10.21203/rs.3.rs-10738655/v1} } @article{corrales2026-7ad35564, author = {Corrales, N. and Vallejo-Bedia, F. and Olivares-Raya, I. and Avila, J. and García-Escudero, V.}, title = {{Autophagy Stimulation by Intermittent Fasting and Its Potential Neuroprotective Role in Alzheimer’s Disease}}, journal = {Preprints.org}, year = {2026}, doi = {10.20944/preprints202608.1636.v1}, url = {https://doi.org/10.20944/preprints202608.1636.v1} } @article{fragola2026-76961fd3, author = {Fragola, G. and Weeks, R. D. and Wolter, J. and Bryan, A. F. and Kapfer, K. N. and Tian, X. and Necarsulmer, J. C. and Evangelista, B. A. and others}, title = {{High-Content Screening Identifies Dithiocarbamates As A Class Of Chemicals That Disrupts TDP-43 Proteostasis}}, journal = {bioRxiv}, year = {2026}, doi = {10.64898/2026.08.14.741835}, url = {https://doi.org/10.64898/2026.08.14.741835} } @article{maiese2027-42545731, author = {Maiese, Kenneth}, title = {{Oxidative stress, aging, metabolism, SIRT1, and the gut microbiota: the neurocardiac basis of cognitive loss}}, journal = {Medical gas research}, year = {2027}, doi = {10.4103/mgr.medgasres-d-26-00073}, pmid = {42545731}, url = {https://doi.org/10.4103/mgr.medgasres-d-26-00073} } @article{sun2025-41296937, author = {Sun, Li and Chen, Chu}, title = {{Senescence in Aging and Alzheimer's Disease}}, journal = {Aging and disease}, year = {2025}, doi = {10.14336/ad.2025.1201}, pmid = {41296937}, url = {https://doi.org/10.14336/ad.2025.1201} } @article{chen2025-41268687, author = {Chen, J. and Liu, B. and Yao, X. and Yang, X. and Sun, J. and Yi, J. and Xue, F. and Zhang, J. and others}, title = {{AMPK/SIRT1/PGC-1α Signaling Pathway: Molecular Mechanisms and Targeted Strategies From Energy Homeostasis Regulation to Disease Therapy}}, journal = {CNS neuroscience \& therapeutics}, year = {2025}, doi = {10.1111/cns.70657}, pmid = {41268687}, url = {https://doi.org/10.1111/cns.70657} } @article{kemna2025-41070365, author = {Kemna, Riley E and Szabo-Reed, Amanda and Mayfield, Hana D and Kueck, Paul J and Pennington, Jenae and John, Casey S and Hauger, Brittany M and Wilkins, Heather M and others}, title = {{Mitochondrial blood-based biomarker is related to cardiorespiratory fitness and aging in a sex-dependent manner}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2025}, doi = {10.1002/trc2.70163}, pmid = {41070365}, url = {https://doi.org/10.1002/trc2.70163} } @article{stefano2025-41047006, author = {Stefano, George B and Büttiker, Pascal and Weissenberger, Simon and Raboch, Jiri and Anders, Martin}, title = {{Semaglutide and the pathogenesis of progressive neurodegenerative disease: the central role of mitochondria}}, journal = {Frontiers in neuroendocrinology}, year = {2025}, doi = {10.1016/j.yfrne.2025.101217}, pmid = {41047006}, url = {https://doi.org/10.1016/j.yfrne.2025.101217} } @article{zubillaga2025-40992081, author = {Zubillaga, Marlene and Abadin, Xenia and Ivars, Elia and Puigròs, Margalida and Trullas, Ramon and Bellini, M José and Arnal, Nathalie and Colell, Anna}, title = {{Copper overload worsens the inflammatory response of microglia to amyloid beta (Aβ) by impairing phagocytosis and promoting mitochondrial DNA-mediated NLRP3 inflammasome activation}}, journal = {Redox biology}, year = {2025}, doi = {10.1016/j.redox.2025.103872}, pmid = {40992081}, url = {https://doi.org/10.1016/j.redox.2025.103872} } @article{hu2025-40729740, author = {Hu, Liubing and Li, Jianshuang and Guo, Haolin and Su, Lei and Dong, Peina and Huang, Juan and Liu, Yanyan and Liu, Xinjie and others}, title = {{SENP6 Maintains Mitochondrial Homeostasis by Regulating Mitochondrial Protein Import Through deSUMOylation of TOM40}}, journal = {Advanced science (Weinheim, Baden-Wurttemberg, Germany)}, year = {2025}, doi = {10.1002/advs.202503408}, pmid = {40729740}, url = {https://doi.org/10.1002/advs.202503408} } @article{kansakar2025-40166284, author = {Kansakar, Sahan Bs and Sterben, Sydney P and Anamala, Charitha C and Thielen, Mitchell D and Liaudanskaya, Volha}, title = {{The Silent Saboteur: How Mitochondria Shape the Long-Term Fate of the Injured Brain}}, journal = {bioRxiv : the preprint server for biology}, year = {2025}, doi = {10.1101/2025.03.19.644244}, pmid = {40166284}, url = {https://doi.org/10.1101/2025.03.19.644244} } @article{ning2024-39522311, author = {Ning, Zhenqiu and Zhong, Xiaoqin and Wang, Yu and Hu, Dafeng and Tang, Xialin and Deng, Minzhen}, title = {{Cerebral ischemic injury impairs autophagy and exacerbates cognitive impairment in APP/PS1 mice}}, journal = {International immunopharmacology}, year = {2024}, doi = {10.1016/j.intimp.2024.113581}, pmid = {39522311}, url = {https://doi.org/10.1016/j.intimp.2024.113581} } @article{gao2024-39577323, author = {Gao, Qi-Chao and Liu, Ge-Liang and Wang, Qi and Zhang, Sheng-Xiao and Ji, Zhi-Lin and Wang, Zhao-Jun and Wu, Mei-Na and Yu, Qi and others}, title = {{A promising drug repurposing approach for Alzheimer's treatment: Givinostat improves cognitive behavior and pathological features in APP/PS1 mice}}, journal = {Redox biology}, year = {2024}, doi = {10.1016/j.redox.2024.103420}, pmid = {39577323}, url = {https://doi.org/10.1016/j.redox.2024.103420} } @article{firdous2024-38832985, author = {Firdous, Sayed Mohammed and Khan, Sahabaj Ali and Maity, Amritangshu}, title = {{Oxidative stress-mediated neuroinflammation in Alzheimer's disease}}, journal = {Naunyn-Schmiedeberg's archives of pharmacology}, year = {2024}, doi = {10.1007/s00210-024-03188-3}, pmid = {38832985}, url = {https://doi.org/10.1007/s00210-024-03188-3} } @article{qin2024-38577947, author = {Qin, Pei and Sun, Ye and Li, Liya}, title = {{Mitochondrial dysfunction in chronic neuroinflammatory diseases (Review)}}, journal = {International journal of molecular medicine}, year = {2024}, doi = {10.3892/ijmm.2024.5371}, pmid = {38577947}, url = {https://doi.org/10.3892/ijmm.2024.5371} } @article{calvorodriguez2024-38238819, author = {Calvo-Rodriguez, M. and Kharitonova, E. K. and Snyder, A. C. and Hou, S. S. and Sanchez-Mico, M. V. and Das, S. and Fan, Z. and Shirani, H. and others}, title = {{Real-time imaging of mitochondrial redox reveals increased mitochondrial oxidative stress associated with amyloid β aggregates in vivo in a mouse model of Alzheimer's disease}}, journal = {Molecular neurodegeneration}, year = {2024}, doi = {10.1186/s13024-024-00702-2}, pmid = {38238819}, url = {https://doi.org/10.1186/s13024-024-00702-2} } @article{feng2024-38229533, author = {Feng, Yiyuan and Xu, Zhongyun and Jin, Hongfu and Chen, Yuanyuan and Fu, Chenglai and Zhang, Yu and Yin, Yafu and Wang, Hui and others}, title = {{Metformin ameliorates mitochondrial damage induced by C9orf72 poly(GR) via upregulating AKT phosphorylation}}, journal = {Journal of cellular biochemistry}, year = {2024}, doi = {10.1002/jcb.30526}, pmid = {38229533}, url = {https://doi.org/10.1002/jcb.30526} } @article{dhapola2024-38165499, author = {Dhapola, R. and Beura, S. K. and Sharma, P. and Singh, S. K. and HariKrishnaReddy, D.}, title = {{Oxidative stress in Alzheimer's disease: current knowledge of signaling pathways and therapeutics}}, journal = {Molecular biology reports}, year = {2024}, doi = {10.1007/s11033-023-09021-z}, pmid = {38165499}, url = {https://doi.org/10.1007/s11033-023-09021-z} } @article{anzovino2023-38132159, author = {Anzovino, A. and Canepa, E. and Alves, M. and Lemon, N. L. and Carare, R. O. and Fossati, S.}, title = {{Amyloid Beta Oligomers Activate Death Receptors and Mitochondria-Mediated Apoptotic Pathways in Cerebral Vascular Smooth Muscle Cells; Protective Effects of Carbonic Anhydrase Inhibitors}}, journal = {Cells}, year = {2023}, doi = {10.3390/cells12242840}, pmid = {38132159}, url = {https://doi.org/10.3390/cells12242840} } @article{jomova2023-37597078, author = {Jomova, K. and Raptova, R. and Alomar, S. Y. and Alwasel, S. H. and Nepovimova, E. and Kuca, K. and Valko, M.}, title = {{Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging}}, journal = {Archives of toxicology}, year = {2023}, doi = {10.1007/s00204-023-03562-9}, pmid = {37597078}, url = {https://doi.org/10.1007/s00204-023-03562-9} } @article{casanova2023-37179826, author = {Casanova, A. and Wevers, A. and Navarro-Ledesma, S. and Pruimboom, L.}, title = {{Mitochondria: It is all about energy}}, journal = {Frontiers in physiology}, year = {2023}, doi = {10.3389/fphys.2023.1114231}, pmid = {37179826}, url = {https://doi.org/10.3389/fphys.2023.1114231} } @article{wang2023-37437985, author = {Wang, Qiangqiang and Adil, Muhammad Zeeshan and Xie, Xiaoliang and Zhao, Shihao and Zhang, Ju and Huang, Zebo}, title = {{Therapeutic targeting of mitochondria-proteostasis axis by antioxidant polysaccharides in neurodegeneration}}, journal = {Advances in protein chemistry and structural biology}, year = {2023}, doi = {10.1016/bs.apcsb.2023.02.017}, pmid = {37437985}, url = {https://doi.org/10.1016/bs.apcsb.2023.02.017} } @article{jagtap2023-36968195, author = {Jagtap, Yuvraj Anandrao and Kumar, Prashant and Kinger, Sumit and Dubey, Ankur Rakesh and Choudhary, Akash and Gutti, Ravi Kumar and Singh, Sarika and Jha, Hem Chandra and others}, title = {{Disturb mitochondrial associated proteostasis: Neurodegeneration and imperfect ageing}}, journal = {Frontiers in cell and developmental biology}, year = {2023}, doi = {10.3389/fcell.2023.1146564}, pmid = {36968195}, url = {https://doi.org/10.3389/fcell.2023.1146564} } @article{costa2023-36894028, author = {Costa, I. and Barbosa, D. J. and Benfeito, S. and Silva, V. and Chavarria, D. and Borges, F. and Remião, F. and Silva, R.}, title = {{Molecular mechanisms of ferroptosis and their involvement in brain diseases}}, journal = {Pharmacology \& therapeutics}, year = {2023}, doi = {10.1016/j.pharmthera.2023.108373}, pmid = {36894028}, url = {https://doi.org/10.1016/j.pharmthera.2023.108373} } @article{wang2023-36820164, author = {Wang, Weixia and Li, Yijin and Meng, Xianfang}, title = {{Vitamin D and neurodegenerative diseases}}, journal = {Heliyon}, year = {2023}, doi = {10.1016/j.heliyon.2023.e12877}, pmid = {36820164}, url = {https://doi.org/10.1016/j.heliyon.2023.e12877} } @article{kalinichenko2023-36640726, author = {Kalinichenko, Andrei L and Jappy, David and Solius, Georgy M and Maltsev, Dmitry I and Bogdanova, Yulia A and Mukhametshina, Liana F and Sokolov, Rostislav A and Moshchenko, Aleksandr A and others}, title = {{Chemogenetic emulation of intraneuronal oxidative stress affects synaptic plasticity}}, journal = {Redox biology}, year = {2023}, doi = {10.1016/j.redox.2023.102604}, pmid = {36640726}, url = {https://doi.org/10.1016/j.redox.2023.102604} } @article{jomova2022-36152810, author = {Jomova, K. and Makova, M. and Alomar, S. Y. and Alwasel, S. H. and Nepovimova, E. and Kuca, K. and Rhodes, C. J. and Valko, M.}, title = {{Essential metals in health and disease}}, journal = {Chemico-biological interactions}, year = {2022}, doi = {10.1016/j.cbi.2022.110173}, pmid = {36152810}, url = {https://doi.org/10.1016/j.cbi.2022.110173} } @article{teleanu2022-35682615, author = {Teleanu, D. M. and Niculescu, A. G. and Lungu, II. and Radu, C. I. and Vladâcenco, O. and Roza, E. and Costăchescu, B. and Grumezescu, A. M. and others}, title = {{An Overview of Oxidative Stress, Neuroinflammation, and Neurodegenerative Diseases}}, journal = {International journal of molecular sciences}, year = {2022}, doi = {10.3390/ijms23115938}, pmid = {35682615}, url = {https://doi.org/10.3390/ijms23115938} } @article{chen2022-35669462, author = {Chen, Huiyi and Chen, Feng and Jiang, Ying and Zhang, Lu and Hu, Guizhen and Sun, Furong and Zhang, Miaoping and Ji, Yao and others}, title = {{A Review of ApoE4 Interference Targeting Mitophagy Molecular Pathways for Alzheimer's Disease}}, journal = {Frontiers in aging neuroscience}, year = {2022}, doi = {10.3389/fnagi.2022.881239}, pmid = {35669462}, url = {https://doi.org/10.3389/fnagi.2022.881239} } @article{bai2022-35395415, author = {Bai, R. and Guo, J. and Ye, X. Y. and Xie, Y. and Xie, T.}, title = {{Oxidative stress: The core pathogenesis and mechanism of Alzheimer's disease}}, journal = {Ageing research reviews}, year = {2022}, doi = {10.1016/j.arr.2022.101619}, pmid = {35395415}, url = {https://doi.org/10.1016/j.arr.2022.101619} } @article{li2022-35411309, author = {Li, Y. and Zhao, T. and Li, J. and Xia, M. and Wang, X. and Liu, C. and Zheng, T. and others}, title = {{Oxidative Stress and 4-hydroxy-2-nonenal (4-HNE): Implications in the Pathogenesis and Treatment of Aging-related Diseases}}, journal = {Journal of immunology research}, year = {2022}, doi = {10.1155/2022/2233906}, pmid = {35411309}, url = {https://doi.org/10.1155/2022/2233906} } @article{talebi2022-35093121, author = {Talebi, Marjan and Vadoud, Seyyed Ali Mohammadi and Haratian, Alireza and Talebi, Mohsen and Farkhondeh, Tahereh and Pourbagher-Shahri, Ali Mohammad and Samarghandian, Saeed}, title = {{The interplay between oxidative stress and autophagy: focus on the development of neurological diseases}}, journal = {Behavioral and brain functions : BBF}, year = {2022}, doi = {10.1186/s12993-022-00187-3}, pmid = {35093121}, url = {https://doi.org/10.1186/s12993-022-00187-3} } @article{beard2021-35087428, author = {Beard, E. and Lengacher, S. and Dias, S. and Magistretti, P. J. and Finsterwald, C.}, title = {{Astrocytes as Key Regulators of Brain Energy Metabolism: New Therapeutic Perspectives}}, journal = {Frontiers in physiology}, year = {2021}, doi = {10.3389/fphys.2021.825816}, pmid = {35087428}, url = {https://doi.org/10.3389/fphys.2021.825816} } @article{guo2022-34889504, author = {Guo, Jing and Chiang, Wei-Chung}, title = {{Mitophagy in aging and longevity}}, journal = {IUBMB life}, year = {2022}, doi = {10.1002/iub.2585}, pmid = {34889504}, url = {https://doi.org/10.1002/iub.2585} } @article{nisa2021-34433343, author = {Nisa, Fatema Yasmin and Rahman, Md Atiar and Hossen, Md Amjad and Khan, Mohammad Forhad and Khan, Md Asif Nadim and Majid, Mumtahina and Sultana, Farjana and Haque, Md Areeful}, title = {{Role of neurotoxicants in the pathogenesis of Alzheimer's disease: a mechanistic insight}}, journal = {Annals of medicine}, year = {2021}, doi = {10.1080/07853890.2021.1966088}, pmid = {34433343}, url = {https://doi.org/10.1080/07853890.2021.1966088} } @article{hou2021-34497121, author = {Hou, Yujun and Wei, Yong and Lautrup, Sofie and Yang, Beimeng and Wang, Yue and Cordonnier, Stephanie and Mattson, Mark P and Croteau, Deborah L and others}, title = {{NAD+ supplementation reduces neuroinflammation and cell senescence in a transgenic mouse model of Alzheimer's disease via cGAS-STING}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2021}, doi = {10.1073/pnas.2011226118}, pmid = {34497121}, url = {https://doi.org/10.1073/pnas.2011226118} } @article{carmona2021-34564349, author = {Carmona, A. and Roudeau, S. and Ortega, R.}, title = {{Molecular Mechanisms of Environmental Metal Neurotoxicity: A Focus on the Interactions of Metals with Synapse Structure and Function}}, journal = {Toxics}, year = {2021}, doi = {10.3390/toxics9090198}, pmid = {34564349}, url = {https://doi.org/10.3390/toxics9090198} } @article{ionescutucker2021-34416493, author = {Ionescu-Tucker, A. and Cotman, C. W.}, title = {{Emerging roles of oxidative stress in brain aging and Alzheimer's disease}}, journal = {Neurobiology of aging}, year = {2021}, doi = {10.1016/j.neurobiolaging.2021.07.014}, pmid = {34416493}, url = {https://doi.org/10.1016/j.neurobiolaging.2021.07.014} } @article{forman2021-34194012, author = {Forman, H. J. and Zhang, H.}, title = {{Targeting oxidative stress in disease: promise and limitations of antioxidant therapy}}, journal = {Nature reviews. Drug discovery}, year = {2021}, doi = {10.1038/s41573-021-00233-1}, pmid = {34194012}, url = {https://doi.org/10.1038/s41573-021-00233-1} } @article{xie2021-33895160, author = {Xie, Y. and Zheng, J. and Li, S. and Li, H. and Zhou, Y. and Zheng, W. and Zhang, M. and Liu, L. and others}, title = {{GLP-1 improves the neuronal supportive ability of astrocytes in Alzheimer's disease by regulating mitochondrial dysfunction via the cAMP/PKA pathway}}, journal = {Biochemical pharmacology}, year = {2021}, doi = {10.1016/j.bcp.2021.114578}, pmid = {33895160}, url = {https://doi.org/10.1016/j.bcp.2021.114578} } @article{park2021-33774476, author = {Park, M. W. and Cha, H. W. and Kim, J. and Kim, J. H. and Yang, H. and Yoon, S. and Boonpraman, N. and Yi, S. S. and others}, title = {{NOX4 promotes ferroptosis of astrocytes by oxidative stress-induced lipid peroxidation via the impairment of mitochondrial metabolism in Alzheimer's diseases}}, journal = {Redox biology}, year = {2021}, doi = {10.1016/j.redox.2021.101947}, pmid = {33774476}, url = {https://doi.org/10.1016/j.redox.2021.101947} } @article{dacunzo2021-33579698, author = {D'Acunzo, P. and Pérez-González, R. and Kim, Y. and Hargash, T. and Miller, C. and Alldred, M. J. and Erdjument-Bromage, H. and Penikalapati, S. C. and others}, title = {{Mitovesicles are a novel population of extracellular vesicles of mitochondrial origin altered in Down syndrome}}, journal = {Science advances}, year = {2021}, doi = {10.1126/sciadv.abe5085}, pmid = {33579698}, url = {https://doi.org/10.1126/sciadv.abe5085} } @article{grinanferre2021-33571701, author = {Griñán-Ferré, C. and Bellver-Sanchis, A. and Izquierdo, V. and Corpas, R. and Roig-Soriano, J. and Chillón, M. and Andres-Lacueva, C. and Somogyvári, M. and others}, title = {{The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer's disease pathology: From antioxidant to epigenetic therapy}}, journal = {Ageing research reviews}, year = {2021}, doi = {10.1016/j.arr.2021.101271}, pmid = {33571701}, url = {https://doi.org/10.1016/j.arr.2021.101271} } @article{yan2021-33536413, author = {Yan, H. F. and Zou, T. and Tuo, Q. Z. and Xu, S. and Li, H. and Belaidi, A. A. and Lei, P.}, title = {{Ferroptosis: mechanisms and links with diseases}}, journal = {Signal transduction and targeted therapy}, year = {2021}, doi = {10.1038/s41392-020-00428-9}, pmid = {33536413}, url = {https://doi.org/10.1038/s41392-020-00428-9} } @article{zhu2021-33347985, author = {Zhu, Li and Zhou, Qionglin and He, Lu and Chen, Linxi}, title = {{Mitochondrial unfolded protein response: An emerging pathway in human diseases}}, journal = {Free radical biology \& medicine}, year = {2021}, doi = {10.1016/j.freeradbiomed.2020.12.013}, pmid = {33347985}, url = {https://doi.org/10.1016/j.freeradbiomed.2020.12.013} } @article{quinn2020-33168089, author = {Quinn, P. M. J. and Moreira, P. I. and Ambrósio, A. F. and Alves, C. H.}, title = {{PINK1/PARKIN signalling in neurodegeneration and neuroinflammation}}, journal = {Acta neuropathologica communications}, year = {2020}, doi = {10.1186/s40478-020-01062-w}, pmid = {33168089}, url = {https://doi.org/10.1186/s40478-020-01062-w} } @article{cunnane2020-32709961, author = {Cunnane, S. C. and Trushina, E. and Morland, C. and Prigione, A. and Casadesus, G. and Andrews, Z. B. and Beal, M. F. and Bergersen, L. H. and others}, title = {{Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing}}, journal = {Nature reviews. Drug discovery}, year = {2020}, doi = {10.1038/s41573-020-0072-x}, pmid = {32709961}, url = {https://doi.org/10.1038/s41573-020-0072-x} } @article{xie2020-32717200, author = {Xie, Zhuoya and Wu, Hongrong and Zhao, Jianfeng}, title = {{Multifunctional roles of zinc in Alzheimer's disease}}, journal = {Neurotoxicology}, year = {2020}, doi = {10.1016/j.neuro.2020.07.003}, pmid = {32717200}, url = {https://doi.org/10.1016/j.neuro.2020.07.003} } @article{lee2021-32704090, author = {Lee, H. J. and Jung, Y. H. and Choi, G. E. and Kim, J. S. and Chae, C. W. and Lim, JR. and Kim, S. Y. and Yoon, J. H. and others}, title = {{Urolithin A suppresses high glucose-induced neuronal amyloidogenesis by modulating TGM2-dependent ER-mitochondria contacts and calcium homeostasis}}, journal = {Cell death and differentiation}, year = {2021}, doi = {10.1038/s41418-020-0593-1}, pmid = {32704090}, url = {https://doi.org/10.1038/s41418-020-0593-1} } @article{picca2020-32707949, author = {Picca, A. and Calvani, R. and Coelho-Junior, H. J. and Landi, F. and Bernabei, R. and Marzetti, E.}, title = {{Mitochondrial Dysfunction, Oxidative Stress, and Neuroinflammation: Intertwined Roads to Neurodegeneration}}, journal = {Antioxidants (Basel, Switzerland)}, year = {2020}, doi = {10.3390/antiox9080647}, pmid = {32707949}, url = {https://doi.org/10.3390/antiox9080647} } @article{tyagi2020-32485218, author = {Tyagi, Alpna and Mirita, Carol and Taher, Nadine and Shah, Iman and Moeller, Emily and Tyagi, Anit and Chong, Thomas and Pugazhenthi, Subbiah}, title = {{Metabolic syndrome exacerbates amyloid pathology in a comorbid Alzheimer's mouse model}}, journal = {Biochimica et biophysica acta. Molecular basis of disease}, year = {2020}, doi = {10.1016/j.bbadis.2020.165849}, pmid = {32485218}, url = {https://doi.org/10.1016/j.bbadis.2020.165849} } @article{wang2020-32471464, author = {Wang, W. and Zhao, F. and Ma, X. and Perry, G. and Zhu, X.}, title = {{Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: recent advances}}, journal = {Molecular neurodegeneration}, year = {2020}, doi = {10.1186/s13024-020-00376-6}, pmid = {32471464}, url = {https://doi.org/10.1186/s13024-020-00376-6} } @article{farkhondeh2020-32358751, author = {Farkhondeh, T. and Mehrpour, O. and Forouzanfar, F. and Roshanravan, B. and Samarghandian, S.}, title = {{Oxidative stress and mitochondrial dysfunction in organophosphate pesticide-induced neurotoxicity and its amelioration: a review}}, journal = {Environmental science and pollution research international}, year = {2020}, doi = {10.1007/s11356-020-09045-z}, pmid = {32358751}, url = {https://doi.org/10.1007/s11356-020-09045-z} } @article{weidling2020-32339611, author = {Weidling, Ian W and Swerdlow, Russell H}, title = {{Mitochondria in Alzheimer's disease and their potential role in Alzheimer's proteostasis}}, journal = {Experimental neurology}, year = {2020}, doi = {10.1016/j.expneurol.2020.113321}, pmid = {32339611}, url = {https://doi.org/10.1016/j.expneurol.2020.113321} } @article{tower2020-32201219, author = {Tower, John and Pomatto, Laura C D and Davies, Kelvin J A}, title = {{Sex differences in the response to oxidative and proteolytic stress}}, journal = {Redox biology}, year = {2020}, doi = {10.1016/j.redox.2020.101488}, pmid = {32201219}, url = {https://doi.org/10.1016/j.redox.2020.101488} } @article{martinezcue2020-32116562, author = {Martínez-Cué, C. and Rueda, N.}, title = {{Cellular Senescence in Neurodegenerative Diseases}}, journal = {Frontiers in cellular neuroscience}, year = {2020}, doi = {10.3389/fncel.2020.00016}, pmid = {32116562}, url = {https://doi.org/10.3389/fncel.2020.00016} } @article{llanosgonzalez2019-32063825, author = {Llanos-González, Emilio and Henares-Chavarino, Ángel Andres and Pedrero-Prieto, Cristina María and García-Carpintero, Sonia and Frontiñán-Rubio, Javier and Sancho-Bielsa, Francisco Javier and Alcain, Francisco Javier and Peinado, Juan Ramón and others}, title = {{Interplay Between Mitochondrial Oxidative Disorders and Proteostasis in Alzheimer's Disease}}, journal = {Frontiers in neuroscience}, year = {2019}, doi = {10.3389/fnins.2019.01444}, pmid = {32063825}, url = {https://doi.org/10.3389/fnins.2019.01444} } @article{agnihotri2020-31829802, author = {Agnihotri, A. and Aruoma, O. I.}, title = {{Alzheimer's Disease and Parkinson's Disease: A Nutritional Toxicology Perspective of the Impact of Oxidative Stress, Mitochondrial Dysfunction, Nutrigenomics and Environmental Chemicals}}, journal = {Journal of the American College of Nutrition}, year = {2020}, doi = {10.1080/07315724.2019.1683379}, pmid = {31829802}, url = {https://doi.org/10.1080/07315724.2019.1683379} } @article{vandervelpen2019-31779690, author = {van der Velpen, V. and Teav, T. and Gallart-Ayala, H. and Mehl, F. and Konz, I. and Clark, C. and Oikonomidi, A. and Peyratout, G. and others}, title = {{Systemic and central nervous system metabolic alterations in Alzheimer's disease}}, journal = {Alzheimer's research \& therapy}, year = {2019}, doi = {10.1186/s13195-019-0551-7}, pmid = {31779690}, url = {https://doi.org/10.1186/s13195-019-0551-7} } @article{nandi2019-31827713, author = {Nandi, A. and Yan, L. J. and Jana, C. K. and Das, N.}, title = {{Role of Catalase in Oxidative Stress- and Age-Associated Degenerative Diseases}}, journal = {Oxidative medicine and cellular longevity}, year = {2019}, doi = {10.1155/2019/9613090}, pmid = {31827713}, url = {https://doi.org/10.1155/2019/9613090} } @article{benit2019-31697708, author = {Bénit, Paule and Kahn, Agathe and Chrétien, Dominique and Bortoli, Sylvie and Laurence Therese, H. U. C. and Schiff, Manuel and Gimenez‐Roqueplo, Anne‐Paule and Favier, Judith and others}, title = {{Evolutionarily conserved susceptibility of the mitochondrial respiratory chain to SDHI pesticides and its consequence on the impact of SDHIs on human cultured cells}}, journal = {PLoS ONE}, year = {2019}, doi = {10.1371/journal.pone.0224132}, pmid = {31697708}, url = {https://doi.org/10.1371/journal.pone.0224132} } @article{lautrup2019-31577933, author = {Lautrup, S. and Sinclair, D. A. and Mattson, M. P. and Fang, E. F.}, title = {{NAD + in Brain Aging and Neurodegenerative Disorders}}, journal = {Cell metabolism}, year = {2019}, doi = {10.1016/j.cmet.2019.09.001}, pmid = {31577933}, url = {https://doi.org/10.1016/j.cmet.2019.09.001} } @article{hou2019-31501588, author = {Hou, Y. and Dan, X. and Babbar, M. and Wei, Y. and Hasselbalch, S. G. and Croteau, D. L. and Bohr, V. A.}, title = {{Ageing as a risk factor for neurodegenerative disease}}, journal = {Nature reviews. Neurology}, year = {2019}, doi = {10.1038/s41582-019-0244-7}, pmid = {31501588}, url = {https://doi.org/10.1038/s41582-019-0244-7} } @article{fecher2019-31501572, author = {Fecher, C. and Trovò, L. and Müller, S. A. and Snaidero, N. and Wettmarshausen, J. and Heink, S. and Ortiz, O. and Wagner, I. and others}, title = {{Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity}}, journal = {Nature neuroscience}, year = {2019}, doi = {10.1038/s41593-019-0479-z}, pmid = {31501572}, url = {https://doi.org/10.1038/s41593-019-0479-z} } @article{george2020-31369712, author = {George, Akash K and Majumder, Avisek and Ice, Hayley and Homme, Rubens P and Eyob, Wintana and Tyagi, Suresh C and Singh, Mahavir}, title = {{Genes and genetics in hyperhomocysteinemia and the "1-carbon metabolism": implications for retinal structure and eye functions}}, journal = {Canadian journal of physiology and pharmacology}, year = {2020}, doi = {10.1139/cjpp-2019-0236}, pmid = {31369712}, url = {https://doi.org/10.1139/cjpp-2019-0236} } @article{singh2019-31013638, author = {Singh, A. and Kukreti, R. and Saso, L. and Kukreti, S.}, title = {{Oxidative Stress: A Key Modulator in Neurodegenerative Diseases}}, journal = {Molecules (Basel, Switzerland)}, year = {2019}, doi = {10.3390/molecules24081583}, pmid = {31013638}, url = {https://doi.org/10.3390/molecules24081583} } @article{fang2019-30742114, author = {Fang, E. F. and Hou, Y. and Palikaras, K. and Adriaanse, B. A. and Kerr, J. S. and Yang, B. and Lautrup, S. and Hasan-Olive, M. M. and others}, title = {{Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease}}, journal = {Nature neuroscience}, year = {2019}, doi = {10.1038/s41593-018-0332-9}, pmid = {30742114}, url = {https://doi.org/10.1038/s41593-018-0332-9} } @article{sivandzade2019-30576920, author = {Sivandzade, F. and Prasad, S. and Bhalerao, A. and Cucullo, L.}, title = {{NRF2 and NF-қB interplay in cerebrovascular and neurodegenerative disorders: Molecular mechanisms and possible therapeutic approaches}}, journal = {Redox biology}, year = {2019}, doi = {10.1016/j.redox.2018.11.017}, pmid = {30576920}, url = {https://doi.org/10.1016/j.redox.2018.11.017} } @article{muhammad2019-30478761, author = {Muhammad, T. and Ali, T. and Ikram, M. and Khan, A. and Alam, S. I. and Kim, M. O.}, title = {{Melatonin Rescue Oxidative Stress-Mediated Neuroinflammation/ Neurodegeneration and Memory Impairment in Scopolamine-Induced Amnesia Mice Model}}, journal = {Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology}, year = {2019}, doi = {10.1007/s11481-018-9824-3}, pmid = {30478761}, url = {https://doi.org/10.1007/s11481-018-9824-3} } @article{savelieff2019-30095897, author = {Savelieff, M. G. and Nam, G. and Kang, J. and Lee, H. J. and Lee, M. and Lim, M. H.}, title = {{Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis in the Last Decade}}, journal = {Chemical reviews}, year = {2019}, doi = {10.1021/acs.chemrev.8b00138}, pmid = {30095897}, url = {https://doi.org/10.1021/acs.chemrev.8b00138} } @article{shen2018-29937713, author = {Shen, Y. and Ye, B. and Chen, P. and Wang, Q. and Fan, C. and Shu, Y. and Xiang, M.}, title = {{Cognitive Decline, Dementia, Alzheimer's Disease and Presbycusis: Examination of the Possible Molecular Mechanism}}, journal = {Frontiers in neuroscience}, year = {2018}, doi = {10.3389/fnins.2018.00394}, pmid = {29937713}, url = {https://doi.org/10.3389/fnins.2018.00394} } @article{hou2018-29432159, author = {Hou, Y. and Lautrup, S. and Cordonnier, S. and Wang, Y. and Croteau, D. L. and Zavala, E. and Zhang, Y. and Moritoh, K. and others}, title = {{NAD + supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2018}, doi = {10.1073/pnas.1718819115}, pmid = {29432159}, url = {https://doi.org/10.1073/pnas.1718819115} } @article{swerdlow2018-29036828, author = {Swerdlow, R. H.}, title = {{Mitochondria and Mitochondrial Cascades in Alzheimer's Disease}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2018}, doi = {10.3233/jad-170585}, pmid = {29036828}, url = {https://doi.org/10.3233/jad-170585} } @article{sorrentino2017-29211722, author = {Sorrentino, V. and Romani, M. and Mouchiroud, L. and Beck, J. S. and Zhang, H. and D'Amico, D. and Moullan, N. and Potenza, F. and others}, title = {{Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity}}, journal = {Nature}, year = {2017}, doi = {10.1038/nature25143}, pmid = {29211722}, url = {https://doi.org/10.1038/nature25143} } @article{cheignon2018-29080524, author = {Cheignon, C. and Tomas, M. and Bonnefont-Rousselot, D. and Faller, P. and Hureau, C. and Collin, F.}, title = {{Oxidative stress and the amyloid beta peptide in Alzheimer's disease}}, journal = {Redox biology}, year = {2018}, doi = {10.1016/j.redox.2017.10.014}, pmid = {29080524}, url = {https://doi.org/10.1016/j.redox.2017.10.014} } @article{sawda2017-28815614, author = {Sawda, Christine and Moussa, Charbel and Turner, R Scott}, title = {{Resveratrol for Alzheimer's disease}}, journal = {Annals of the New York Academy of Sciences}, year = {2017}, doi = {10.1111/nyas.13431}, pmid = {28815614}, url = {https://doi.org/10.1111/nyas.13431} } @article{liu2017-28785371, author = {Liu, Z. and Zhou, T. and Ziegler, A. C. and Dimitrion, P. and Zuo, L.}, title = {{Oxidative Stress in Neurodegenerative Diseases: From Molecular Mechanisms to Clinical Applications}}, journal = {Oxidative medicine and cellular longevity}, year = {2017}, doi = {10.1155/2017/2525967}, pmid = {28785371}, url = {https://doi.org/10.1155/2017/2525967} } @article{rojo2017-28704727, author = {Rojo, Ana Isabel and Pajares, Marta and Rada, Patricia and Núñez, Ángel and Nevado‐Holgado, Alejo J. and Killick, Richard and VAN LEUVEN, Fred and Ribé, Elena M. and others}, title = {{NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology}}, journal = {Redox Biology}, year = {2017}, doi = {10.1016/j.redox.2017.07.006}, pmid = {28704727}, url = {https://doi.org/10.1016/j.redox.2017.07.006} } @article{poprac2017-28551354, author = {Poprac, P. and Jomova, K. and Simunkova, M. and Kollar, V. and Rhodes, C. J. and Valko, M.}, title = {{Targeting Free Radicals in Oxidative Stress-Related Human Diseases}}, journal = {Trends in pharmacological sciences}, year = {2017}, doi = {10.1016/j.tips.2017.04.005}, pmid = {28551354}, url = {https://doi.org/10.1016/j.tips.2017.04.005} } @article{camandola2017-28438892, author = {Camandola, S. and Mattson, M. P.}, title = {{Brain metabolism in health, aging, and neurodegeneration}}, journal = {The EMBO journal}, year = {2017}, doi = {10.15252/embj.201695810}, pmid = {28438892}, url = {https://doi.org/10.15252/embj.201695810} } @article{cacabelos2017-28273839, author = {Cacabelos, R.}, title = {{Parkinson's Disease: From Pathogenesis to Pharmacogenomics}}, journal = {International journal of molecular sciences}, year = {2017}, doi = {10.3390/ijms18030551}, pmid = {28273839}, url = {https://doi.org/10.3390/ijms18030551} } @article{kerr2017-28190529, author = {Kerr, J. S. and Adriaanse, B. A. and Greig, N. H. and Mattson, M. P. and Cader, M. Z. and Bohr, V. A. and Fang, E. F.}, title = {{Mitophagy and Alzheimer's Disease: Cellular and Molecular Mechanisms}}, journal = {Trends in neurosciences}, year = {2017}, doi = {10.1016/j.tins.2017.01.002}, pmid = {28190529}, url = {https://doi.org/10.1016/j.tins.2017.01.002} } @article{pugazhenthi2017-28253987, author = {Pugazhenthi, S}, title = {{Metabolic Syndrome and the Cellular Phase of Alzheimer's Disease}}, journal = {Progress in molecular biology and translational science}, year = {2017}, doi = {10.1016/bs.pmbts.2016.12.016}, pmid = {28253987}, url = {https://doi.org/10.1016/bs.pmbts.2016.12.016} } @article{hambright2017-28212525, author = {Hambright, W. S. and Fonseca, R. S. and Chen, L. and Na, R. and Ran, Q.}, title = {{Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration}}, journal = {Redox biology}, year = {2017}, doi = {10.1016/j.redox.2017.01.021}, pmid = {28212525}, url = {https://doi.org/10.1016/j.redox.2017.01.021} } @article{tonnies2017-28059794, author = {Tönnies, E. and Trushina, E.}, title = {{Oxidative Stress, Synaptic Dysfunction, and Alzheimer's Disease}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2017}, doi = {10.3233/jad-161088}, pmid = {28059794}, url = {https://doi.org/10.3233/jad-161088} } @article{raefsky2017-27908782, author = {Raefsky, S. M. and Mattson, M. P.}, title = {{Adaptive responses of neuronal mitochondria to bioenergetic challenges: Roles in neuroplasticity and disease resistance}}, journal = {Free radical biology \& medicine}, year = {2017}, doi = {10.1016/j.freeradbiomed.2016.11.045}, pmid = {27908782}, url = {https://doi.org/10.1016/j.freeradbiomed.2016.11.045} } @article{islam2017-27809706, author = {Islam, M. T.}, title = {{Oxidative stress and mitochondrial dysfunction-linked neurodegenerative disorders}}, journal = {Neurological research}, year = {2017}, doi = {10.1080/01616412.2016.1251711}, pmid = {27809706}, url = {https://doi.org/10.1080/01616412.2016.1251711} } @article{salim2017-27754930, author = {Salim, S.}, title = {{Oxidative Stress and the Central Nervous System}}, journal = {The Journal of pharmacology and experimental therapeutics}, year = {2017}, doi = {10.1124/jpet.116.237503}, pmid = {27754930}, url = {https://doi.org/10.1124/jpet.116.237503} } @article{jha2017-27345267, author = {Jha, Saurabh Kumar and Jha, Niraj Kumar and Kumar, Dhiraj and Ambasta, Rashmi K and Kumar, Pravir}, title = {{Linking mitochondrial dysfunction, metabolic syndrome and stress signaling in Neurodegeneration}}, journal = {Biochimica et biophysica acta. Molecular basis of disease}, year = {2017}, doi = {10.1016/j.bbadis.2016.06.015}, pmid = {27345267}, url = {https://doi.org/10.1016/j.bbadis.2016.06.015} } @article{tramutola2017-27316747, author = {Tramutola, A. and Lanzillotta, C. and Perluigi, M. and Butterfield, D. A.}, title = {{Oxidative stress, protein modification and Alzheimer disease}}, journal = {Brain research bulletin}, year = {2017}, doi = {10.1016/j.brainresbull.2016.06.005}, pmid = {27316747}, url = {https://doi.org/10.1016/j.brainresbull.2016.06.005} } @article{chakrabarti2016-27114843, author = {Chakrabarti, Sasanka and Mohanakumar, Kochupurackal P}, title = {{Aging and Neurodegeneration: A Tangle of Models and Mechanisms}}, journal = {Aging and disease}, year = {2016}, doi = {10.14336/ad.2016.0312}, pmid = {27114843}, url = {https://doi.org/10.14336/ad.2016.0312} } @article{huang2016-27123241, author = {Huang, W. J. and Zhang, X. and Chen, W. W.}, title = {{Role of oxidative stress in Alzheimer's disease}}, journal = {Biomedical reports}, year = {2016}, doi = {10.3892/br.2016.630}, pmid = {27123241}, url = {https://doi.org/10.3892/br.2016.630} } @article{kwon2016-26844592, author = {Kwon, Hyek Jin and Cha, Moon-Yong and Kim, Dokyoon and Kim, Dong‐Kyu and Soh, Min and Shin, Kwangsoo and Hyeon, Taeghwan and Mook‐Jung, Inhee}, title = {{Mitochondria-Targeting Ceria Nanoparticles as Antioxidants for Alzheimer’s Disease}}, journal = {ACS Nano}, year = {2016}, doi = {10.1021/acsnano.5b08045}, pmid = {26844592}, url = {https://doi.org/10.1021/acsnano.5b08045} } @article{kim2015-26713080, author = {Kim, G. H. and Kim, J. E. and Rhie, S. J. and Yoon, S.}, title = {{The Role of Oxidative Stress in Neurodegenerative Diseases}}, journal = {Experimental neurobiology}, year = {2015}, doi = {10.5607/en.2015.24.4.325}, pmid = {26713080}, url = {https://doi.org/10.5607/en.2015.24.4.325} } @article{valko2016-26343967, author = {Valko, M. and Jomova, K. and Rhodes, C. J. and Kuča, K. and Musílek, K.}, title = {{Redox- and non-redox-metal-induced formation of free radicals and their role in human disease}}, journal = {Archives of toxicology}, year = {2016}, doi = {10.1007/s00204-015-1579-5}, pmid = {26343967}, url = {https://doi.org/10.1007/s00204-015-1579-5} } @article{bhat2015-26349970, author = {Bhat, A. H. and Dar, K. B. and Anees, S. and Zargar, M. A. and Masood, A. and Sofi, M. A. and Ganie, S. A.}, title = {{Oxidative stress, mitochondrial dysfunction and neurodegenerative diseases; a mechanistic insight}}, journal = {Biomedicine \& pharmacotherapy = Biomedecine \& pharmacotherapie}, year = {2015}, doi = {10.1016/j.biopha.2015.07.025}, pmid = {26349970}, url = {https://doi.org/10.1016/j.biopha.2015.07.025} } @article{chen2015-26119225, author = {Chen, L. and Na, R. and Boldt, E. and Ran, Q.}, title = {{NLRP3 inflammasome activation by mitochondrial reactive oxygen species plays a key role in long-term cognitive impairment induced by paraquat exposure}}, journal = {Neurobiology of aging}, year = {2015}, doi = {10.1016/j.neurobiolaging.2015.05.018}, pmid = {26119225}, url = {https://doi.org/10.1016/j.neurobiolaging.2015.05.018} } @article{fischer2015-25834699, author = {Fischer, R. and Maier, O.}, title = {{Interrelation of oxidative stress and inflammation in neurodegenerative disease: role of TNF}}, journal = {Oxidative medicine and cellular longevity}, year = {2015}, doi = {10.1155/2015/610813}, pmid = {25834699}, url = {https://doi.org/10.1155/2015/610813} } @article{cervellati2015-40e45779, author = {Cervellati, Carlo and Romani, Arianna and Bergamini, Carlo M. and Bosi, Cristina and Sanz, Juana Maria and Passaro, Angelina and Zuliani, Giovanni}, title = {{PON-1 and ferroxidase activities in older patients with mild cognitive impairment, late onset Alzheimer’s disease or vascular dementia}}, journal = {Clinical Chemistry and Laboratory Medicine (CCLM)}, year = {2015}, doi = {10.1515/cclm-2014-0803}, url = {https://doi.org/10.1515/cclm-2014-0803} } @article{burte2015-25486875, author = {Burté, F. and Carelli, V. and Chinnery, P. F. and Yu-Wai-Man, P.}, title = {{Disturbed mitochondrial dynamics and neurodegenerative disorders}}, journal = {Nature reviews. Neurology}, year = {2015}, doi = {10.1038/nrneurol.2014.228}, pmid = {25486875}, url = {https://doi.org/10.1038/nrneurol.2014.228} } @article{ali2015-25401971, author = {Ali, T. and Badshah, H. and Kim, T. H. and Kim, M. O.}, title = {{Melatonin attenuates D-galactose-induced memory impairment, neuroinflammation and neurodegeneration via RAGE/NF-K B/JNK signaling pathway in aging mouse model}}, journal = {Journal of pineal research}, year = {2015}, doi = {10.1111/jpi.12194}, pmid = {25401971}, url = {https://doi.org/10.1111/jpi.12194} } @article{kamat2014-24807843, author = {Kamat, Pradip K and Kalani, Anuradha and Kyles, Philip and Tyagi, Suresh C and Tyagi, Neetu}, title = {{Autophagy of mitochondria: a promising therapeutic target for neurodegenerative disease}}, journal = {Cell biochemistry and biophysics}, year = {2014}, doi = {10.1007/s12013-014-0006-5}, pmid = {24807843}, url = {https://doi.org/10.1007/s12013-014-0006-5} } @article{slimen2014-25354680, author = {Slimen, I. B. and Najar, T. and Ghram, A. and Dabbebi, H. and Ben Mrad, M. and Abdrabbah, M.}, title = {{Reactive oxygen species, heat stress and oxidative-induced mitochondrial damage. A review}}, journal = {International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group}, year = {2014}, doi = {10.3109/02656736.2014.971446}, pmid = {25354680}, url = {https://doi.org/10.3109/02656736.2014.971446} } @article{ward2014-25231526, author = {Ward, R. J. and Zucca, F. A. and Duyn, J. H. and Crichton, R. R. and Zecca, L.}, title = {{The role of iron in brain ageing and neurodegenerative disorders}}, journal = {The Lancet. Neurology}, year = {2014}, doi = {10.1016/s1474-4422(14)70117-6}, pmid = {25231526}, url = {https://doi.org/10.1016/s1474-4422(14)70117-6} } @article{phaniendra2015-25646037, author = {Phaniendra, A. and Jestadi, D. B. and Periyasamy, L.}, title = {{Free radicals: properties, sources, targets, and their implication in various diseases}}, journal = {Indian journal of clinical biochemistry : IJCB}, year = {2015}, doi = {10.1007/s12291-014-0446-0}, pmid = {25646037}, url = {https://doi.org/10.1007/s12291-014-0446-0} } @article{vang2014-24891994, author = {Vang, S. and Longley, K. and Steer, C. J. and Low, W. C.}, title = {{The Unexpected Uses of Urso- and Tauroursodeoxycholic Acid in the Treatment of Non-liver Diseases}}, journal = {Global advances in health and medicine}, year = {2014}, doi = {10.7453/gahmj.2014.017}, pmid = {24891994}, url = {https://doi.org/10.7453/gahmj.2014.017} } @article{modgil2014-24847438, author = {Modgil, S. and Lahiri, D. K. and Sharma, V. L. and Anand, A.}, title = {{Role of early life exposure and environment on neurodegeneration: implications on brain disorders}}, journal = {Translational neurodegeneration}, year = {2014}, doi = {10.1186/2047-9158-3-9}, pmid = {24847438}, url = {https://doi.org/10.1186/2047-9158-3-9} } @article{shichiri2014-24895477, author = {Shichiri, M.}, title = {{The role of lipid peroxidation in neurological disorders}}, journal = {Journal of clinical biochemistry and nutrition}, year = {2014}, doi = {10.3164/jcbn.14-10}, pmid = {24895477}, url = {https://doi.org/10.3164/jcbn.14-10} } @article{herskovits2014-24507186, author = {Herskovits, A. Z. and Guarente, L.}, title = {{SIRT1 in neurodevelopment and brain senescence}}, journal = {Neuron}, year = {2014}, doi = {10.1016/j.neuron.2014.01.028}, pmid = {24507186}, url = {https://doi.org/10.1016/j.neuron.2014.01.028} } @article{valero2014-24606795, author = {Valero, T.}, title = {{Mitochondrial biogenesis: pharmacological approaches}}, journal = {Current pharmaceutical design}, year = {2014}, doi = {10.2174/138161282035140911142118}, pmid = {24606795}, url = {https://doi.org/10.2174/138161282035140911142118} } @article{farr2014-24355211, author = {Farr, S. A. and Ripley, J. L. and Sultana, R. and Zhang, Z. and Niehoff, M. L. and Platt, T. L. and Murphy, M. P. and Morley, J. E. and others}, title = {{Antisense oligonucleotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer disease}}, journal = {Free radical biology \& medicine}, year = {2014}, doi = {10.1016/j.freeradbiomed.2013.11.014}, pmid = {24355211}, url = {https://doi.org/10.1016/j.freeradbiomed.2013.11.014} } @article{wang2014-24189435, author = {Wang, X. and Wang, W. and Li, L. and Perry, G. and Lee, H. G. and Zhu, X.}, title = {{Oxidative stress and mitochondrial dysfunction in Alzheimer's disease}}, journal = {Biochimica et biophysica acta}, year = {2014}, doi = {10.1016/j.bbadis.2013.10.015}, pmid = {24189435}, url = {https://doi.org/10.1016/j.bbadis.2013.10.015} } @article{swerdlow2014-24071439, author = {Swerdlow, R. H. and Burns, J. M. and Khan, S. M.}, title = {{The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives}}, journal = {Biochimica et biophysica acta}, year = {2014}, doi = {10.1016/j.bbadis.2013.09.010}, pmid = {24071439}, url = {https://doi.org/10.1016/j.bbadis.2013.09.010} } @article{zhao2013-23983897, author = {Zhao, Y. and Zhao, B.}, title = {{Oxidative stress and the pathogenesis of Alzheimer's disease}}, journal = {Oxidative medicine and cellular longevity}, year = {2013}, doi = {10.1155/2013/316523}, pmid = {23983897}, url = {https://doi.org/10.1155/2013/316523} } @article{guo2013-25206509, author = {Guo, C. and Sun, L. and Chen, X. and Zhang, D.}, title = {{Oxidative stress, mitochondrial damage and neurodegenerative diseases}}, journal = {Neural regeneration research}, year = {2013}, doi = {10.3969/j.issn.1673-5374.2013.21.009}, pmid = {25206509}, url = {https://doi.org/10.3969/j.issn.1673-5374.2013.21.009} } @article{mehta2013-23123057, author = {Mehta, A. and Prabhakar, M. and Kumar, P. and Deshmukh, R. and Sharma, P. L.}, title = {{Excitotoxicity: bridge to various triggers in neurodegenerative disorders}}, journal = {European journal of pharmacology}, year = {2013}, doi = {10.1016/j.ejphar.2012.10.032}, pmid = {23123057}, url = {https://doi.org/10.1016/j.ejphar.2012.10.032} } @article{sultana2013-23044265, author = {Sultana, R. and Perluigi, M. and Butterfield, D. A.}, title = {{Lipid peroxidation triggers neurodegeneration: a redox proteomics view into the Alzheimer disease brain}}, journal = {Free radical biology \& medicine}, year = {2013}, doi = {10.1016/j.freeradbiomed.2012.09.027}, pmid = {23044265}, url = {https://doi.org/10.1016/j.freeradbiomed.2012.09.027} } @article{marrache2012-22991470, author = {Marrache, Sean and Dhar, Shanta}, title = {{Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics}}, journal = {Proceedings of the National Academy of Sciences}, year = {2012}, doi = {10.1073/pnas.1210096109}, pmid = {22991470}, url = {https://doi.org/10.1073/pnas.1210096109} } @article{wu2013-22995439, author = {Wu, J. and Ding, T. and Sun, J.}, title = {{Neurotoxic potential of iron oxide nanoparticles in the rat brain striatum and hippocampus}}, journal = {Neurotoxicology}, year = {2013}, doi = {10.1016/j.neuro.2012.09.006}, pmid = {22995439}, url = {https://doi.org/10.1016/j.neuro.2012.09.006} } @article{bhat2012-22984612, author = {Bhat, Rekha V and Crowe, Elizabeth P. and Bitto, Alessandro and Moh, Michelle and Katsetos, Christos D. and Garcia, Fernando U. and Johnson, F. Brad and Trojanowski, John Q. and others}, title = {{Astrocyte Senescence as a Component of Alzheimer’s Disease}}, journal = {PLoS ONE}, year = {2012}, doi = {10.1371/journal.pone.0045069}, pmid = {22984612}, url = {https://doi.org/10.1371/journal.pone.0045069} } @article{pandiperumal2013-22739839, author = {Pandi-Perumal, SR. and BaHammam, A. S. and Brown, G. M. and Spence, D. W. and Bharti, V. K. and Kaur, C. and Hardeland, R. and Cardinali, D. P.}, title = {{Melatonin antioxidative defense: therapeutical implications for aging and neurodegenerative processes}}, journal = {Neurotoxicity research}, year = {2013}, doi = {10.1007/s12640-012-9337-4}, pmid = {22739839}, url = {https://doi.org/10.1007/s12640-012-9337-4} } @article{johri2012-22700435, author = {Johri, A. and Beal, M. F.}, title = {{Mitochondrial dysfunction in neurodegenerative diseases}}, journal = {The Journal of pharmacology and experimental therapeutics}, year = {2012}, doi = {10.1124/jpet.112.192138}, pmid = {22700435}, url = {https://doi.org/10.1124/jpet.112.192138} } @article{federico2012-22669122, author = {Federico, A. and Cardaioli, E. and Da Pozzo, P. and Formichi, P. and Gallus, G. N. and Radi, E.}, title = {{Mitochondria, oxidative stress and neurodegeneration}}, journal = {Journal of the neurological sciences}, year = {2012}, doi = {10.1016/j.jns.2012.05.030}, pmid = {22669122}, url = {https://doi.org/10.1016/j.jns.2012.05.030} } @article{stafstrom2012-22509165, author = {Stafstrom, C. E. and Rho, J. M.}, title = {{The ketogenic diet as a treatment paradigm for diverse neurological disorders}}, journal = {Frontiers in pharmacology}, year = {2012}, doi = {10.3389/fphar.2012.00059}, pmid = {22509165}, url = {https://doi.org/10.3389/fphar.2012.00059} } @article{venkateshappa2012-22461064, author = {Venkateshappa, C. and Harish, G. and Mahadevan, A. and Srinivas Bharath, M. M. and Shankar, S. K.}, title = {{Elevated oxidative stress and decreased antioxidant function in the human hippocampus and frontal cortex with increasing age: implications for neurodegeneration in Alzheimer's disease}}, journal = {Neurochemical research}, year = {2012}, doi = {10.1007/s11064-012-0755-8}, pmid = {22461064}, url = {https://doi.org/10.1007/s11064-012-0755-8} } @article{rahman2012-d1417822, author = {Rahman, Taibur and Hosen, Md. Ismail and Islam, Md. Monirul and Shekhar, Hossain Uddin}, title = {{Oxidative stress and human health}}, journal = {Advances in Bioscience and Biotechnology}, year = {2012}, doi = {10.4236/abb.2012.327123}, url = {https://doi.org/10.4236/abb.2012.327123} } @article{chasapis2012-22071549, author = {Chasapis, C. T. and Loutsidou, A. C. and Spiliopoulou, C. A. and Stefanidou, M. E.}, title = {{Zinc and human health: an update}}, journal = {Archives of toxicology}, year = {2012}, doi = {10.1007/s00204-011-0775-1}, pmid = {22071549}, url = {https://doi.org/10.1007/s00204-011-0775-1} } @article{kummer2011-21903077, author = {Kummer, M. P. and Hermes, M. and Delekarte, A. and Hammerschmidt, T. and Kumar, S. and Terwel, D. and Walter, J. and Pape, H. C. and others}, title = {{Nitration of tyrosine 10 critically enhances amyloid β aggregation and plaque formation}}, journal = {Neuron}, year = {2011}, doi = {10.1016/j.neuron.2011.07.001}, pmid = {21903077}, url = {https://doi.org/10.1016/j.neuron.2011.07.001} } @article{calkins2011-21873260, author = {Calkins, M. J. and Manczak, M. and Mao, P. and Shirendeb, U. and Reddy, P. H.}, title = {{Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease}}, journal = {Human molecular genetics}, year = {2011}, doi = {10.1093/hmg/ddr381}, pmid = {21873260}, url = {https://doi.org/10.1093/hmg/ddr381} } @article{steiner2011-21817111, author = {Steiner, J. L. and Murphy, E. A. and McClellan, J. L. and Carmichael, M. D. and Davis, J. M.}, title = {{Exercise training increases mitochondrial biogenesis in the brain}}, journal = {Journal of applied physiology (Bethesda, Md. : 1985)}, year = {2011}, doi = {10.1152/japplphysiol.00343.2011}, pmid = {21817111}, url = {https://doi.org/10.1152/japplphysiol.00343.2011} } @article{hybertson2011-22020111, author = {Hybertson, B. M. and Gao, B. and Bose, S. K. and McCord, J. M.}, title = {{Oxidative stress in health and disease: the therapeutic potential of Nrf2 activation}}, journal = {Molecular aspects of medicine}, year = {2011}, doi = {10.1016/j.mam.2011.10.006}, pmid = {22020111}, url = {https://doi.org/10.1016/j.mam.2011.10.006} } @article{nakamura2011-21597461, author = {Nakamura, T. and Lipton, S. A.}, title = {{Redox modulation by S-nitrosylation contributes to protein misfolding, mitochondrial dynamics, and neuronal synaptic damage in neurodegenerative diseases}}, journal = {Cell death and differentiation}, year = {2011}, doi = {10.1038/cdd.2011.65}, pmid = {21597461}, url = {https://doi.org/10.1038/cdd.2011.65} } @article{manczak2011-21459773, author = {Manczak, M. and Calkins, M. J. and Reddy, P. H.}, title = {{Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage}}, journal = {Human molecular genetics}, year = {2011}, doi = {10.1093/hmg/ddr139}, pmid = {21459773}, url = {https://doi.org/10.1093/hmg/ddr139} } @article{jomova2011-21414382, author = {Jomova, K. and Valko, M.}, title = {{Advances in metal-induced oxidative stress and human disease}}, journal = {Toxicology}, year = {2011}, doi = {10.1016/j.tox.2011.03.001}, pmid = {21414382}, url = {https://doi.org/10.1016/j.tox.2011.03.001} } @article{cyr2011-20919933, author = {Cyr, A. R. and Domann, F. E.}, title = {{The redox basis of epigenetic modifications: from mechanisms to functional consequences}}, journal = {Antioxidants \& redox signaling}, year = {2011}, doi = {10.1089/ars.2010.3492}, pmid = {20919933}, url = {https://doi.org/10.1089/ars.2010.3492} } @article{du2010-20937894, author = {Du, H. and Guo, L. and Yan, S. and Sosunov, A. A. and McKhann, G. M. and Yan, S. S.}, title = {{Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2010}, doi = {10.1073/pnas.1006586107}, pmid = {20937894}, url = {https://doi.org/10.1073/pnas.1006586107} } @article{jomova2010-20730621, author = {Jomova, K. and Vondrakova, D. and Lawson, M. and Valko, M.}, title = {{Metals, oxidative stress and neurodegenerative disorders}}, journal = {Molecular and cellular biochemistry}, year = {2010}, doi = {10.1007/s11010-010-0563-x}, pmid = {20730621}, url = {https://doi.org/10.1007/s11010-010-0563-x} } @article{wang2010-20552050, author = {Wang, X. and Michaelis, E. K.}, title = {{Selective neuronal vulnerability to oxidative stress in the brain}}, journal = {Frontiers in aging neuroscience}, year = {2010}, doi = {10.3389/fnagi.2010.00012}, pmid = {20552050}, url = {https://doi.org/10.3389/fnagi.2010.00012} } @article{vingtdeux2010-20080969, author = {Vingtdeux, Valérie and Giliberto, Luca and Zhao, Haitian and Chandakkar, Pallavi and Wu, Qingli and Simon, James Edward and Janle, Elsa M. and Lobo, Jessica and others}, title = {{AMP-activated Protein Kinase Signaling Activation by Resveratrol Modulates Amyloid-β Peptide Metabolism}}, journal = {Journal of Biological Chemistry}, year = {2010}, doi = {10.1074/jbc.m109.060061}, pmid = {20080969}, url = {https://doi.org/10.1074/jbc.m109.060061} } @article{kim2010-20079433, author = {Kim, E. K. and Choi, E. J.}, title = {{Pathological roles of MAPK signaling pathways in human diseases}}, journal = {Biochimica et biophysica acta}, year = {2010}, doi = {10.1016/j.bbadis.2009.12.009}, pmid = {20079433}, url = {https://doi.org/10.1016/j.bbadis.2009.12.009} } @article{santilli2010-20052410, author = {Santilli, G. and Lamorte, G. and Carlessi, L. and Ferrari, D. and Rota Nodari, L. and Binda, E. and Delia, D. and Vescovi, A. L. and others}, title = {{Mild hypoxia enhances proliferation and multipotency of human neural stem cells}}, journal = {PloS one}, year = {2010}, doi = {10.1371/journal.pone.0008575}, pmid = {20052410}, url = {https://doi.org/10.1371/journal.pone.0008575} } @article{jornayvaz2010-20533901, author = {Jornayvaz, F. R. and Shulman, G. I.}, title = {{Regulation of mitochondrial biogenesis}}, journal = {Essays in biochemistry}, year = {2010}, doi = {10.1042/bse0470069}, pmid = {20533901}, url = {https://doi.org/10.1042/bse0470069} } @article{chen2009-19808793, author = {Chen, H. and Chan, D. C.}, title = {{Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases}}, journal = {Human molecular genetics}, year = {2009}, doi = {10.1093/hmg/ddp326}, pmid = {19808793}, url = {https://doi.org/10.1093/hmg/ddp326} } @article{yao2009-19667196, author = {Yao, J. and Irwin, R. W. and Zhao, L. and Nilsen, J. and Hamilton, R. T. and Brinton, R. D.}, title = {{Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2009}, doi = {10.1073/pnas.0903563106}, pmid = {19667196}, url = {https://doi.org/10.1073/pnas.0903563106} } @article{wang2009-19605646, author = {Wang, X. and Su, B. and Lee, H. G. and Li, X. and Perry, G. and Smith, M. A. and Zhu, X.}, title = {{Impaired balance of mitochondrial fission and fusion in Alzheimer's disease}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2009}, doi = {10.1523/jneurosci.1357-09.2009}, pmid = {19605646}, url = {https://doi.org/10.1523/jneurosci.1357-09.2009} } @article{chen2009-19559056, author = {Chen, J. Q. and Cammarata, P. R. and Baines, C. P. and Yager, J. D.}, title = {{Regulation of mitochondrial respiratory chain biogenesis by estrogens/estrogen receptors and physiological, pathological and pharmacological implications}}, journal = {Biochimica et biophysica acta}, year = {2009}, doi = {10.1016/j.bbamcr.2009.06.001}, pmid = {19559056}, url = {https://doi.org/10.1016/j.bbamcr.2009.06.001} } @article{cho2009-19342591, author = {Cho, D. H. and Nakamura, T. and Fang, J. and Cieplak, P. and Godzik, A. and Gu, Z. and Lipton, S. A.}, title = {{S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury}}, journal = {Science (New York, N.Y.)}, year = {2009}, doi = {10.1126/science.1171091}, pmid = {19342591}, url = {https://doi.org/10.1126/science.1171091} } @article{ballatori2009-19166318, author = {Ballatori, N. and Krance, S. M. and Notenboom, S. and Shi, S. and Tieu, K. and Hammond, C. L.}, title = {{Glutathione dysregulation and the etiology and progression of human diseases}}, journal = {Biological chemistry}, year = {2009}, doi = {10.1515/bc.2009.033}, pmid = {19166318}, url = {https://doi.org/10.1515/bc.2009.033} } @article{uttara2009-19721819, author = {Uttara, B. and Singh, A. V. and Zamboni, P. and Mahajan, R. T.}, title = {{Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options}}, journal = {Current neuropharmacology}, year = {2009}, doi = {10.2174/157015909787602823}, pmid = {19721819}, url = {https://doi.org/10.2174/157015909787602823} } @article{kong2009-19225343, author = {Kong, G. Y. and Van Bergen, N. J. and Trounce, I. A. and Crowston, J. G.}, title = {{Mitochondrial dysfunction and glaucoma}}, journal = {Journal of glaucoma}, year = {2009}, doi = {10.1097/ijg.0b013e318181284f}, pmid = {19225343}, url = {https://doi.org/10.1097/ijg.0b013e318181284f} } @article{chen2009-22084578, author = {Chen, Y. and Guillemin, G. J.}, title = {{Kynurenine pathway metabolites in humans: disease and healthy States}}, journal = {International journal of tryptophan research : IJTR}, year = {2009}, doi = {10.4137/ijtr.s2097}, pmid = {22084578}, url = {https://doi.org/10.4137/ijtr.s2097} } @article{knott2008-19076450, author = {Knott, A. B. and Bossy-Wetzel, E.}, title = {{Impairing the mitochondrial fission and fusion balance: a new mechanism of neurodegeneration}}, journal = {Annals of the New York Academy of Sciences}, year = {2008}, doi = {10.1196/annals.1427.030}, pmid = {19076450}, url = {https://doi.org/10.1196/annals.1427.030} } @article{mattson2008-19081372, author = {Mattson, M. P. and Gleichmann, M. and Cheng, A.}, title = {{Mitochondria in neuroplasticity and neurological disorders}}, journal = {Neuron}, year = {2008}, doi = {10.1016/j.neuron.2008.10.010}, pmid = {19081372}, url = {https://doi.org/10.1016/j.neuron.2008.10.010} } @article{migliore2009-18952194, author = {Migliore, L. and Coppedè, F.}, title = {{Environmental-induced oxidative stress in neurodegenerative disorders and aging}}, journal = {Mutation research}, year = {2009}, doi = {10.1016/j.mrgentox.2008.09.013}, pmid = {18952194}, url = {https://doi.org/10.1016/j.mrgentox.2008.09.013} } @article{du2008-18806802, author = {Du, H. and Guo, L. and Fang, F. and Chen, D. and Sosunov, A. A. and McKhann, G. M. and Yan, Y. and Wang, C. and others}, title = {{Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease}}, journal = {Nature medicine}, year = {2008}, doi = {10.1038/nm.1868}, pmid = {18806802}, url = {https://doi.org/10.1038/nm.1868} } @article{shelat2008-18346200, author = {Shelat, P. B. and Chalimoniuk, M. and Wang, J. H. and Strosznajder, J. B. and Lee, J. C. and Sun, A. Y. and Simonyi, A. and Sun, G. Y.}, title = {{Amyloid beta peptide and NMDA induce ROS from NADPH oxidase and AA release from cytosolic phospholipase A2 in cortical neurons}}, journal = {Journal of neurochemistry}, year = {2008}, doi = {10.1111/j.1471-4159.2008.05347.x}, pmid = {18346200}, url = {https://doi.org/10.1111/j.1471-4159.2008.05347.x} } @article{reed2008-18442411, author = {Reed, M. C. and Thomas, R. L. and Pavisic, J. and James, S. J. and Ulrich, C. M. and Nijhout, H. F.}, title = {{A mathematical model of glutathione metabolism}}, journal = {Theoretical biology \& medical modelling}, year = {2008}, doi = {10.1186/1742-4682-5-8}, pmid = {18442411}, url = {https://doi.org/10.1186/1742-4682-5-8} } @article{barnham2008-18342639, author = {Barnham, K. J. and Bush, A. I.}, title = {{Metals in Alzheimer's and Parkinson's diseases}}, journal = {Current opinion in chemical biology}, year = {2008}, doi = {10.1016/j.cbpa.2008.02.019}, pmid = {18342639}, url = {https://doi.org/10.1016/j.cbpa.2008.02.019} } @article{liang2008-18332434, author = {Liang, W. S. and Reiman, E. M. and Valla, J. and Dunckley, T. and Beach, T. G. and Grover, A. and Niedzielko, T. L. and Schneider, L. E. and others}, title = {{Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2008}, doi = {10.1073/pnas.0709259105}, pmid = {18332434}, url = {https://doi.org/10.1073/pnas.0709259105} } @article{reddy2008-18218341, author = {Reddy, P. H. and Beal, M. F.}, title = {{Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease}}, journal = {Trends in molecular medicine}, year = {2008}, doi = {10.1016/j.molmed.2007.12.002}, pmid = {18218341}, url = {https://doi.org/10.1016/j.molmed.2007.12.002} } @article{hoye2008-18193822, author = {Hoye, A. T. and Davoren, J. E. and Wipf, P. and Fink, M. P. and Kagan, V. E.}, title = {{Targeting mitochondria}}, journal = {Accounts of chemical research}, year = {2008}, doi = {10.1021/ar700135m}, pmid = {18193822}, url = {https://doi.org/10.1021/ar700135m} } @article{sayre2008-18052107, author = {Sayre, L. M. and Perry, G. and Smith, M. A.}, title = {{Oxidative stress and neurotoxicity}}, journal = {Chemical research in toxicology}, year = {2008}, doi = {10.1021/tx700210j}, pmid = {18052107}, url = {https://doi.org/10.1021/tx700210j} } @article{nunomura2007-18220780, author = {Nunomura, A. and Moreira, P. I. and Lee, H. G. and Zhu, X. and Castellani, R. J. and Smith, M. A. and Perry, G.}, title = {{Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases}}, journal = {CNS \& neurological disorders drug targets}, year = {2007}, doi = {10.2174/187152707783399201}, pmid = {18220780}, url = {https://doi.org/10.2174/187152707783399201} } @article{butterfield2007-17664130, author = {Butterfield, D. A. and Reed, T. and Newman, S. F. and Sultana, R.}, title = {{Roles of amyloid beta-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment}}, journal = {Free radical biology \& medicine}, year = {2007}, doi = {10.1016/j.freeradbiomed.2007.05.037}, pmid = {17664130}, url = {https://doi.org/10.1016/j.freeradbiomed.2007.05.037} } @article{rukhsanasultana2007-17522440, author = {Rukhsana Sultana, A. and Debra Boyd-kimball, A. and Cai, Jain and Pierce, William M. Jr. and Klein, Jon B. and Merchant, Michael L. and Butterfield, David Allan}, title = {{Proteomics Analysis of the Alzheimer's Disease Hippocampal Proteome}}, journal = {Journal of Alzheimer s Disease}, year = {2007}, doi = {10.3233/jad-2007-11203}, pmid = {17522440}, url = {https://doi.org/10.3233/jad-2007-11203} } @article{mattson2007-17328689, author = {Mattson, M. P.}, title = {{Calcium and neurodegeneration}}, journal = {Aging cell}, year = {2007}, doi = {10.1111/j.1474-9726.2007.00275.x}, pmid = {17328689}, url = {https://doi.org/10.1111/j.1474-9726.2007.00275.x} } @article{defelice2007-17308309, author = {De Felice, F. G. and Velasco, P. T. and Lambert, M. P. and Viola, K. and Fernandez, S. J. and Ferreira, S. T. and Klein, W. L.}, title = {{Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine}}, journal = {The Journal of biological chemistry}, year = {2007}, doi = {10.1074/jbc.m607483200}, pmid = {17308309}, url = {https://doi.org/10.1074/jbc.m607483200} } @article{dimarco2007-17019703, author = {DiMarco, T. and Giulivi, C.}, title = {{Current analytical methods for the detection of dityrosine, a biomarker of oxidative stress, in biological samples}}, journal = {Mass spectrometry reviews}, year = {2007}, doi = {10.1002/mas.20109}, pmid = {17019703}, url = {https://doi.org/10.1002/mas.20109} } @article{chen2006-18654167, author = {Chen, J. and Patil, S. and Seal, S. and McGinnis, J. F.}, title = {{Rare earth nanoparticles prevent retinal degeneration induced by intracellular peroxides}}, journal = {Nature nanotechnology}, year = {2006}, doi = {10.1038/nnano.2006.91}, pmid = {18654167}, url = {https://doi.org/10.1038/nnano.2006.91} } @article{zhu2007-17142016, author = {Zhu, X. and Lee, H. G. and Perry, G. and Smith, M. A.}, title = {{Alzheimer disease, the two-hit hypothesis: an update}}, journal = {Biochimica et biophysica acta}, year = {2007}, doi = {10.1016/j.bbadis.2006.10.014}, pmid = {17142016}, url = {https://doi.org/10.1016/j.bbadis.2006.10.014} } @article{valko2007-16978905, author = {Valko, M. and Leibfritz, D. and Moncol, J. and Cronin, M. T. and Mazur, M. and Telser, J.}, title = {{Free radicals and antioxidants in normal physiological functions and human disease}}, journal = {The international journal of biochemistry \& cell biology}, year = {2007}, doi = {10.1016/j.biocel.2006.07.001}, pmid = {16978905}, url = {https://doi.org/10.1016/j.biocel.2006.07.001} } @article{devi2006-16943564, author = {Devi, L. and Prabhu, B. M. and Galati, D. F. and Avadhani, N. G. and Anandatheerthavarada, H. K.}, title = {{Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2006}, doi = {10.1523/jneurosci.1469-06.2006}, pmid = {16943564}, url = {https://doi.org/10.1523/jneurosci.1469-06.2006} } @article{butterfield2006-16860790, author = {Butterfield, D. A. and Perluigi, M. and Sultana, R.}, title = {{Oxidative stress in Alzheimer's disease brain: new insights from redox proteomics}}, journal = {European journal of pharmacology}, year = {2006}, doi = {10.1016/j.ejphar.2006.06.026}, pmid = {16860790}, url = {https://doi.org/10.1016/j.ejphar.2006.06.026} } @article{manczak2006-16551656, author = {Manczak, M. and Anekonda, T. S. and Henson, E. and Park, B. S. and Quinn, J. and Reddy, P. H.}, title = {{Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression}}, journal = {Human molecular genetics}, year = {2006}, doi = {10.1093/hmg/ddl066}, pmid = {16551656}, url = {https://doi.org/10.1093/hmg/ddl066} } @article{sultana2006-16378731, author = {Sultana, R. and Poon, H. F. and Cai, J. and Pierce, W. M. and Merchant, M. and Klein, J. B. and Markesbery, W. R. and Butterfield, D. A.}, title = {{Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach}}, journal = {Neurobiology of disease}, year = {2006}, doi = {10.1016/j.nbd.2005.10.004}, pmid = {16378731}, url = {https://doi.org/10.1016/j.nbd.2005.10.004} } @article{sultana2006-16271804, author = {Sultana, R. and Boyd-Kimball, D. and Poon, H. F. and Cai, J. and Pierce, W. M. and Klein, J. B. and Merchant, M. and Markesbery, W. R. and others}, title = {{Redox proteomics identification of oxidized proteins in Alzheimer's disease hippocampus and cerebellum: an approach to understand pathological and biochemical alterations in AD}}, journal = {Neurobiology of aging}, year = {2006}, doi = {10.1016/j.neurobiolaging.2005.09.021}, pmid = {16271804}, url = {https://doi.org/10.1016/j.neurobiolaging.2005.09.021} } @article{caspersen2005-16210396, author = {Caspersen, C. and Wang, N. and Yao, J. and Sosunov, A. and Chen, X. and Lustbader, J. W. and Xu, H. W. and Stern, D. and others}, title = {{Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease}}, journal = {FASEB journal : official publication of the Federation of American Societies for Experimental Biology}, year = {2005}, doi = {10.1096/fj.05-3735fje}, pmid = {16210396}, url = {https://doi.org/10.1096/fj.05-3735fje} } @article{beal2005-16178023, author = {Beal, M. F.}, title = {{Mitochondria take center stage in aging and neurodegeneration}}, journal = {Annals of neurology}, year = {2005}, doi = {10.1002/ana.20624}, pmid = {16178023}, url = {https://doi.org/10.1002/ana.20624} } @article{ding2005-16207876, author = {Ding, Q. and Markesbery, W. R. and Chen, Q. and Li, F. and Keller, J. N.}, title = {{Ribosome dysfunction is an early event in Alzheimer's disease}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2005}, doi = {10.1523/jneurosci.3040-05.2005}, pmid = {16207876}, url = {https://doi.org/10.1523/jneurosci.3040-05.2005} } @article{uriuadams2005-16112185, author = {Uriu-Adams, J. Y. and Keen, C. L.}, title = {{Copper, oxidative stress, and human health}}, journal = {Molecular aspects of medicine}, year = {2005}, doi = {10.1016/j.mam.2005.07.015}, pmid = {16112185}, url = {https://doi.org/10.1016/j.mam.2005.07.015} } @article{calabrese2005-15896810, author = {Calabrese, V. and Lodi, R. and Tonon, C. and D'Agata, V. and Sapienza, M. and Scapagnini, G. and Mangiameli, A. and Pennisi, G. and others}, title = {{Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia}}, journal = {Journal of the neurological sciences}, year = {2005}, doi = {10.1016/j.jns.2005.03.012}, pmid = {15896810}, url = {https://doi.org/10.1016/j.jns.2005.03.012} } @article{bubber2005-15852400, author = {Bubber, Parvesh and Haroutunian, Vahram H. and Fisch, Gene S. and Blass, John P. and Gibson, Gary E.}, title = {{Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications}}, journal = {Annals of Neurology}, year = {2005}, doi = {10.1002/ana.20474}, pmid = {15852400}, url = {https://doi.org/10.1002/ana.20474} } @article{bazan2005-15912889, author = {Bazan, N. G.}, title = {{Neuroprotectin D1 (NPD1): a DHA-derived mediator that protects brain and retina against cell injury-induced oxidative stress}}, journal = {Brain pathology (Zurich, Switzerland)}, year = {2005}, doi = {10.1111/j.1750-3639.2005.tb00513.x}, pmid = {15912889}, url = {https://doi.org/10.1111/j.1750-3639.2005.tb00513.x} } @article{valko2005-15892631, author = {Valko, M. and Morris, H. and Cronin, M. T.}, title = {{Metals, toxicity and oxidative stress}}, journal = {Current medicinal chemistry}, year = {2005}, doi = {10.2174/0929867053764635}, pmid = {15892631}, url = {https://doi.org/10.2174/0929867053764635} } @article{zecca2004-15496864, author = {Zecca, L. and Youdim, M. B. and Riederer, P. and Connor, JR. and Crichton, R. R.}, title = {{Iron, brain ageing and neurodegenerative disorders}}, journal = {Nature reviews. Neuroscience}, year = {2004}, doi = {10.1038/nrn1537}, pmid = {15496864}, url = {https://doi.org/10.1038/nrn1537} } @article{hahn2004-15365174, author = {Hahn, P. and Qian, Y. and Dentchev, T. and Chen, L. and Beard, J. and Harris, Z. L. and Dunaief, J. L.}, title = {{Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2004}, doi = {10.1073/pnas.0405146101}, pmid = {15365174}, url = {https://doi.org/10.1073/pnas.0405146101} } @article{poon2004-15262209, author = {Poon, H. F. and Joshi, G. and Sultana, R. and Farr, S. A. and Banks, W. A. and Morley, J. E. and Calabrese, V. and Butterfield, D. A.}, title = {{Antisense directed at the Abeta region of APP decreases brain oxidative markers in aged senescence accelerated mice}}, journal = {Brain research}, year = {2004}, doi = {10.1016/j.brainres.2004.05.048}, pmid = {15262209}, url = {https://doi.org/10.1016/j.brainres.2004.05.048} } @article{whiteman2004-15255956, author = {Whiteman, M. and Armstrong, J. S. and Chu, S. H. and Jia-Ling, S. and Wong, B. S. and Cheung, N. S. and Halliwell, B. and Moore, P. K.}, title = {{The novel neuromodulator hydrogen sulfide: an endogenous peroxynitrite 'scavenger'?}}, journal = {Journal of neurochemistry}, year = {2004}, doi = {10.1111/j.1471-4159.2004.02617.x}, pmid = {15255956}, url = {https://doi.org/10.1111/j.1471-4159.2004.02617.x} } @article{miller2004-15150321, author = {Miller, Kyle E. and Sheetz, Michael P.}, title = {{Axonal mitochondrial transport and potential are correlated}}, journal = {Journal of Cell Science}, year = {2004}, doi = {10.1242/jcs.01130}, pmid = {15150321}, url = {https://doi.org/10.1242/jcs.01130} } @article{hitomi2004-15123740, author = {Hitomi, J. and Katayama, T. and Eguchi, Y. and Kudo, T. and Taniguchi, M. and Koyama, Y. and Manabe, T. and Yamagishi, S. and others}, title = {{Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death}}, journal = {The Journal of cell biology}, year = {2004}, doi = {10.1083/jcb.200310015}, pmid = {15123740}, url = {https://doi.org/10.1083/jcb.200310015} } @article{kamoun2004-15221504, author = {Kamoun, P.}, title = {{Endogenous production of hydrogen sulfide in mammals}}, journal = {Amino acids}, year = {2004}, doi = {10.1007/s00726-004-0072-x}, pmid = {15221504}, url = {https://doi.org/10.1007/s00726-004-0072-x} } @article{lustbader2004-15087549, author = {Lustbader, J. W. and Cirilli, M. and Lin, C. and Xu, H. W. and Takuma, K. and Wang, N. and Caspersen, C. and Chen, X. and others}, title = {{ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease}}, journal = {Science (New York, N.Y.)}, year = {2004}, doi = {10.1126/science.1091230}, pmid = {15087549}, url = {https://doi.org/10.1126/science.1091230} } @article{wu2004-14988435, author = {Wu, G. and Fang, Y. Z. and Yang, S. and Lupton, JR. and Turner, N. D.}, title = {{Glutathione metabolism and its implications for health}}, journal = {The Journal of nutrition}, year = {2004}, doi = {10.1093/jn/134.3.489}, pmid = {14988435}, url = {https://doi.org/10.1093/jn/134.3.489} } @article{cutler2004-14970312, author = {Cutler, R. G. and Kelly, J. and Storie, K. and Pedersen, W. A. and Tammara, A. and Hatanpaa, K. and Troncoso, J. C. and Mattson, M. P.}, title = {{Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2004}, doi = {10.1073/pnas.0305799101}, pmid = {14970312}, url = {https://doi.org/10.1073/pnas.0305799101} } @article{abramov2004-14724257, author = {Abramov, Andrey Y. and Canevari, Laura and Duchen, Michael R.}, title = {{β-Amyloid Peptides Induce Mitochondrial Dysfunction and Oxidative Stress in Astrocytes and Death of Neurons through Activation of NADPH Oxidase}}, journal = {Journal of Neuroscience}, year = {2004}, doi = {10.1523/jneurosci.4042-03.2004}, pmid = {14724257}, url = {https://doi.org/10.1523/jneurosci.4042-03.2004} } @article{choi2004-14722078, author = {Choi, J. and Levey, A. I. and Weintraub, S. T. and Rees, H. D. and Gearing, M. and Chin, L. S. and Li, L.}, title = {{Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases}}, journal = {The Journal of biological chemistry}, year = {2004}, doi = {10.1074/jbc.m314124200}, pmid = {14722078}, url = {https://doi.org/10.1074/jbc.m314124200} } @article{emerit2004-14739060, author = {Emerit, J. and Edeas, M. and Bricaire, F.}, title = {{Neurodegenerative diseases and oxidative stress}}, journal = {Biomedicine \& pharmacotherapy = Biomedecine \& pharmacotherapie}, year = {2004}, doi = {10.1016/j.biopha.2003.11.004}, pmid = {14739060}, url = {https://doi.org/10.1016/j.biopha.2003.11.004} } @article{rinaldi2003-12928050, author = {Rinaldi, P. and Polidori, M. C. and Metastasio, A. and Mariani, E. and Mattioli, P. and Cherubini, A. and Catani, M. and Cecchetti, R. and others}, title = {{Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer's disease}}, journal = {Neurobiology of aging}, year = {2003}, doi = {10.1016/s0197-4580(03)00031-9}, pmid = {12928050}, url = {https://doi.org/10.1016/s0197-4580(03)00031-9} } @article{atwood2003-14499458, author = {Atwood, C. S. and Obrenovich, M. E. and Liu, T. and Chan, H. and Perry, G. and Smith, M. A. and Martins, R. N.}, title = {{Amyloid-beta: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-beta}}, journal = {Brain research. Brain research reviews}, year = {2003}, doi = {10.1016/s0165-0173(03)00174-7}, pmid = {14499458}, url = {https://doi.org/10.1016/s0165-0173(03)00174-7} } @article{castegna2003-12787059, author = {Castegna, A. and Thongboonkerd, V. and Klein, J. B. and Lynn, B. and Markesbery, W. R. and Butterfield, D. A.}, title = {{Proteomic identification of nitrated proteins in Alzheimer's disease brain}}, journal = {Journal of neurochemistry}, year = {2003}, doi = {10.1046/j.1471-4159.2003.01786.x}, pmid = {12787059}, url = {https://doi.org/10.1046/j.1471-4159.2003.01786.x} } @article{anandatheerthavarada2003-12695498, author = {Anandatheerthavarada, Hindupur K. and Biswas, Gopa and Robin, Marie‐Anne and Avadhani, Narayan G.}, title = {{Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells}}, journal = {The Journal of Cell Biology}, year = {2003}, doi = {10.1083/jcb.200207030}, pmid = {12695498}, url = {https://doi.org/10.1083/jcb.200207030} } @article{harper2003-12667097, author = {Harper, S. J. and Wilkie, N.}, title = {{MAPKs: new targets for neurodegeneration}}, journal = {Expert opinion on therapeutic targets}, year = {2003}, doi = {10.1517/14728222.7.2.187}, pmid = {12667097}, url = {https://doi.org/10.1517/14728222.7.2.187} } @article{dalledonne2003-12727143, author = {Dalle-Donne, I. and Giustarini, D. and Colombo, R. and Rossi, R. and Milzani, A.}, title = {{Protein carbonylation in human diseases}}, journal = {Trends in molecular medicine}, year = {2003}, doi = {10.1016/s1471-4914(03)00031-5}, pmid = {12727143}, url = {https://doi.org/10.1016/s1471-4914(03)00031-5} } @article{krapfenbauer2003-12650976, author = {Krapfenbauer, K. and Engidawork, E. and Cairns, N. and Fountoulakis, M. and Lubec, G.}, title = {{Aberrant expression of peroxiredoxin subtypes in neurodegenerative disorders}}, journal = {Brain research}, year = {2003}, doi = {10.1016/s0006-8993(02)04243-9}, pmid = {12650976}, url = {https://doi.org/10.1016/s0006-8993(02)04243-9} } @article{mattson2003-12591216, author = {Mattson, M. P. and Shea, T. B.}, title = {{Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders}}, journal = {Trends in neurosciences}, year = {2003}, doi = {10.1016/s0166-2236(03)00032-8}, pmid = {12591216}, url = {https://doi.org/10.1016/s0166-2236(03)00032-8} } @article{dalledonne2003-12589963, author = {Dalle-Donne, I. and Rossi, R. and Giustarini, D. and Milzani, A. and Colombo, R.}, title = {{Protein carbonyl groups as biomarkers of oxidative stress}}, journal = {Clinica chimica acta; international journal of clinical chemistry}, year = {2003}, doi = {10.1016/s0009-8981(03)00003-2}, pmid = {12589963}, url = {https://doi.org/10.1016/s0009-8981(03)00003-2} } @article{melo2003-12507730, author = {Melo, J. B. and Agostinho, P. and Oliveira, C. R.}, title = {{Involvement of oxidative stress in the enhancement of acetylcholinesterase activity induced by amyloid beta-peptide}}, journal = {Neuroscience research}, year = {2003}, doi = {10.1016/s0168-0102(02)00201-8}, pmid = {12507730}, url = {https://doi.org/10.1016/s0168-0102(02)00201-8} } @article{butterfield2002-12607822, author = {Butterfield, D. A.}, title = {{Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review}}, journal = {Free radical research}, year = {2002}, doi = {10.1080/1071576021000049890}, pmid = {12607822}, url = {https://doi.org/10.1080/1071576021000049890} } @article{butterworth2002-12602499, author = {Butterworth, R. F.}, title = {{Pathophysiology of hepatic encephalopathy: a new look at ammonia}}, journal = {Metabolic brain disease}, year = {2002}, doi = {10.1023/a:1021989230535}, pmid = {12602499}, url = {https://doi.org/10.1023/a:1021989230535} } @article{opazo2002-12192006, author = {Opazo, Carlos and Huang, Xudong and Cherny, Robert A. and Moir, Robert D. and Roher, Alex E. and White, Anthony Robert and Cappai, Roberto and Masters, Colin Louis and others}, title = {{Metalloenzyme-like Activity of Alzheimer's Disease β-Amyloid}}, journal = {Journal of Biological Chemistry}, year = {2002}, doi = {10.1074/jbc.m206428200}, pmid = {12192006}, url = {https://doi.org/10.1074/jbc.m206428200} } @article{butterfield2002-12392766, author = {Butterfield, D. A. and Castegna, A. and Lauderback, C. M. and Drake, J.}, title = {{Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death}}, journal = {Neurobiology of aging}, year = {2002}, doi = {10.1016/s0197-4580(01)00340-2}, pmid = {12392766}, url = {https://doi.org/10.1016/s0197-4580(01)00340-2} } @article{castegna2002-12354300, author = {Castegna, A. and Aksenov, M. and Thongboonkerd, V. and Klein, J. B. and Pierce, W. M. and Booze, R. and Markesbery, W. R. and Butterfield, D. A.}, title = {{Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71}}, journal = {Journal of neurochemistry}, year = {2002}, doi = {10.1046/j.1471-4159.2002.01103.x}, pmid = {12354300}, url = {https://doi.org/10.1046/j.1471-4159.2002.01103.x} } @article{castegna2002-12160938, author = {Castegna, A. and Aksenov, M. and Aksenova, M. and Thongboonkerd, V. and Klein, J. B. and Pierce, W. M. and Booze, R. and Markesbery, W. R. and others}, title = {{Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1}}, journal = {Free radical biology \& medicine}, year = {2002}, doi = {10.1016/s0891-5849(02)00914-0}, pmid = {12160938}, url = {https://doi.org/10.1016/s0891-5849(02)00914-0} } @article{pratico2002-12056933, author = {Praticò, D. and Clark, C. M. and Liun, F. and Rokach, J. and Lee, V. Y. and Trojanowski, J. Q.}, title = {{Increase of brain oxidative stress in mild cognitive impairment: a possible predictor of Alzheimer disease}}, journal = {Archives of neurology}, year = {2002}, doi = {10.1001/archneur.59.6.972}, pmid = {12056933}, url = {https://doi.org/10.1001/archneur.59.6.972} } @article{butterfield2002-12031889, author = {Butterfield, D. A. and Lauderback, C. M.}, title = {{Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress}}, journal = {Free radical biology \& medicine}, year = {2002}, doi = {10.1016/s0891-5849(02)00794-3}, pmid = {12031889}, url = {https://doi.org/10.1016/s0891-5849(02)00794-3} } @article{selhub2002-11813080, author = {Selhub, J.}, title = {{Folate, vitamin B12 and vitamin B6 and one carbon metabolism}}, journal = {The journal of nutrition, health \& aging}, year = {2002}, pmid = {11813080} } @article{butterfield2001-11733217, author = {Butterfield, D. A. and Drake, J. and Pocernich, C. and Castegna, A.}, title = {{Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide}}, journal = {Trends in molecular medicine}, year = {2001}, doi = {10.1016/s1471-4914(01)02173-6}, pmid = {11733217}, url = {https://doi.org/10.1016/s1471-4914(01)02173-6} } @article{ermak2001-11483593, author = {Ermak, G. and Morgan, T. E. and Davies, K. J.}, title = {{Chronic overexpression of the calcineurin inhibitory gene DSCR1 (Adapt78) is associated with Alzheimer's disease}}, journal = {The Journal of biological chemistry}, year = {2001}, doi = {10.1074/jbc.m102829200}, pmid = {11483593}, url = {https://doi.org/10.1074/jbc.m102829200} } @article{lauderback2001-11461977, author = {Lauderback, Christopher M. and Hackett, Janna M. and Huang, Feng F. and Keller, Jeffrey N. and Szweda, Luke I. and Markesbery, William R. and Butterfield, David Allan}, title = {{The glial glutamate transporter, GLT‐1, is oxidatively modified by 4‐hydroxy‐2‐nonenal in the Alzheimer's disease brain: the role of Aβ1–42}}, journal = {Journal of Neurochemistry}, year = {2001}, doi = {10.1046/j.1471-4159.2001.00451.x}, pmid = {11461977}, url = {https://doi.org/10.1046/j.1471-4159.2001.00451.x} } @article{pratico2001-11404403, author = {Praticò, D. and Uryu, K. and Leight, S. and Trojanoswki, J. Q. and Lee, V. M.}, title = {{Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2001}, doi = {10.1523/jneurosci.21-12-04183.2001}, pmid = {11404403}, url = {https://doi.org/10.1523/jneurosci.21-12-04183.2001} } @article{hirai2001-11312286, author = {Hirai, K. and Aliev, G. and Nunomura, A. and Fujioka, H. and Russell, R. L. and Atwood, C. S. and Johnson, A. B. and Kress, Y. and others}, title = {{Mitochondrial abnormalities in Alzheimer's disease}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2001}, doi = {10.1523/jneurosci.21-09-03017.2001}, pmid = {11312286}, url = {https://doi.org/10.1523/jneurosci.21-09-03017.2001} } @article{kim2001-11400916, author = {Kim, S. H. and Vlkolinsky, R. and Cairns, N. and Fountoulakis, M. and Lubec, G.}, title = {{The reduction of NADH ubiquinone oxidoreductase 24- and 75-kDa subunits in brains of patients with Down syndrome and Alzheimer's disease}}, journal = {Life sciences}, year = {2001}, doi = {10.1016/s0024-3205(01)01074-8}, pmid = {11400916}, url = {https://doi.org/10.1016/s0024-3205(01)01074-8} } @article{aksenov2001-11246152, author = {Aksenov, M. Y. and Aksenova, M. V. and Butterfield, D. A. and Geddes, J. W. and Markesbery, W. R.}, title = {{Protein oxidation in the brain in Alzheimer's disease}}, journal = {Neuroscience}, year = {2001}, doi = {10.1016/s0306-4522(00)00580-7}, pmid = {11246152}, url = {https://doi.org/10.1016/s0306-4522(00)00580-7} } @article{halliwell2001-11599635, author = {Halliwell, B.}, title = {{Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment}}, journal = {Drugs \& aging}, year = {2001}, doi = {10.2165/00002512-200118090-00004}, pmid = {11599635}, url = {https://doi.org/10.2165/00002512-200118090-00004} } @article{mattson2000-11253364, author = {Mattson, M. P.}, title = {{Apoptosis in neurodegenerative disorders}}, journal = {Nature reviews. Molecular cell biology}, year = {2000}, doi = {10.1038/35040009}, pmid = {11253364}, url = {https://doi.org/10.1038/35040009} } @article{lopez2000-11079563, author = {Lopez, Mary F. and Kristal, Bruce S. and Chernokalskaya, Elena and Lazarev, Alexander V. and Shestopalov, Alexander I. and Bogdanova, Alla and Robinson, Myra H.}, title = {{High-throughput profiling of the mitochondrial proteome using affinity fractionation and automation}}, journal = {Electrophoresis}, year = {2000}, doi = {10.1002/1522-2683(20001001)21:16<3427::aid-elps3427>3.0.co;2-l}, pmid = {11079563}, url = {https://doi.org/10.1002/1522-2683(20001001)21:16<3427::aid-elps3427>3.0.co;2-l} } @article{kruman2000-10995836, author = {Kruman, II. and Culmsee, C. and Chan, S. L. and Kruman, Y. and Guo, Z. and Penix, L. and Mattson, M. P.}, title = {{Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2000}, doi = {10.1523/jneurosci.20-18-06920.2000}, pmid = {10995836}, url = {https://doi.org/10.1523/jneurosci.20-18-06920.2000} } @article{kannan2000-10996508, author = {Kannan, K. and Jain, S. K.}, title = {{Oxidative stress and apoptosis}}, journal = {Pathophysiology : the official journal of the International Society for Pathophysiology}, year = {2000}, doi = {10.1016/s0928-4680(00)00053-5}, pmid = {10996508}, url = {https://doi.org/10.1016/s0928-4680(00)00053-5} } @article{hsu2000-10934145, author = {Hsu, L. J. and Sagara, Y. and Arroyo, A. and Rockenstein, E. and Sisk, A. and Mallory, M. and Wong, J. and Takenouchi, T. and others}, title = {{alpha-synuclein promotes mitochondrial deficit and oxidative stress}}, journal = {The American journal of pathology}, year = {2000}, doi = {10.1016/s0002-9440(10)64553-1}, pmid = {10934145}, url = {https://doi.org/10.1016/s0002-9440(10)64553-1} } @article{schulz2000-10931172, author = {Schulz, J. B. and Lindenau, J. and Seyfried, J. and Dichgans, J.}, title = {{Glutathione, oxidative stress and neurodegeneration}}, journal = {European journal of biochemistry}, year = {2000}, doi = {10.1046/j.1432-1327.2000.01595.x}, pmid = {10931172}, url = {https://doi.org/10.1046/j.1432-1327.2000.01595.x} } @article{smith2000-10899439, author = {Smith, M. A. and Rottkamp, C. A. and Nunomura, A. and Raina, A. K. and Perry, G.}, title = {{Oxidative stress in Alzheimer's disease}}, journal = {Biochimica et biophysica acta}, year = {2000}, doi = {10.1016/s0925-4439(00)00040-5}, pmid = {10899439}, url = {https://doi.org/10.1016/s0925-4439(00)00040-5} } @article{hensley2000-10927169, author = {Hensley, K. and Robinson, K. A. and Gabbita, S. P. and Salsman, S. and Floyd, R. A.}, title = {{Reactive oxygen species, cell signaling, and cell injury}}, journal = {Free radical biology \& medicine}, year = {2000}, doi = {10.1016/s0891-5849(00)00252-5}, pmid = {10927169}, url = {https://doi.org/10.1016/s0891-5849(00)00252-5} } @article{christen2000-10681270, author = {Christen, Y.}, title = {{Oxidative stress and Alzheimer disease}}, journal = {The American journal of clinical nutrition}, year = {2000}, doi = {10.1093/ajcn/71.2.621s}, pmid = {10681270}, url = {https://doi.org/10.1093/ajcn/71.2.621s} } @article{floyd1999-10601882, author = {Floyd, R. A.}, title = {{Antioxidants, oxidative stress, and degenerative neurological disorders}}, journal = {Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)}, year = {1999}, doi = {10.1046/j.1525-1373.1999.d01-140.x}, pmid = {10601882}, url = {https://doi.org/10.1046/j.1525-1373.1999.d01-140.x} } @article{huang1999-10601271, author = {Huang, X. and Cuajungco, M. P. and Atwood, C. S. and Hartshorn, M. A. and Tyndall, J. D. and Hanson, G. R. and Stokes, K. C. and Leopold, M. and others}, title = {{Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction}}, journal = {The Journal of biological chemistry}, year = {1999}, doi = {10.1074/jbc.274.52.37111}, pmid = {10601271}, url = {https://doi.org/10.1074/jbc.274.52.37111} } @article{waggoner1999-10448050, author = {Waggoner, D. J. and Bartnikas, T. B. and Gitlin, J. D.}, title = {{The role of copper in neurodegenerative disease}}, journal = {Neurobiology of disease}, year = {1999}, doi = {10.1006/nbdi.1999.0250}, pmid = {10448050}, url = {https://doi.org/10.1006/nbdi.1999.0250} } @article{huang1999-10386999, author = {Huang, X. and Atwood, C. S. and Hartshorn, M. A. and Multhaup, G. and Goldstein, L. E. and Scarpa, R. C. and Cuajungco, M. P. and Gray, D. N. and others}, title = {{The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction}}, journal = {Biochemistry}, year = {1999}, doi = {10.1021/bi990438f}, pmid = {10386999}, url = {https://doi.org/10.1021/bi990438f} } @article{boven1999-10201964, author = {Boven, Leonie A. and Gomes, Lucio and Héry, Christiane and Gray, Françoise and Verhoef, J. and Portegies, Peter and Tardieu, Marc and Nottet, Hans S.L.M.}, title = {{Increased Peroxynitrite Activity in AIDS Dementia Complex: Implications for the Neuropathogenesis of HIV-1 Infection}}, journal = {The Journal of Immunology}, year = {1999}, doi = {10.4049/jimmunol.162.7.4319}, pmid = {10201964}, url = {https://doi.org/10.4049/jimmunol.162.7.4319} } @article{nunomura1999-10066249, author = {Nunomura, Akihiko and Perry, George L. and Pappolla, Miguel A. and Wade, Ramon and Hirai, Keisuke and Chiba, Shigeru and Smith, Mark A.}, title = {{RNA Oxidation Is a Prominent Feature of Vulnerable Neurons in Alzheimer’s Disease}}, journal = {Journal of Neuroscience}, year = {1999}, doi = {10.1523/jneurosci.19-06-01959.1999}, pmid = {10066249}, url = {https://doi.org/10.1523/jneurosci.19-06-01959.1999} } @article{love1999-10071053, author = {Love, S. and Barber, R. and Wilcock, G. K.}, title = {{Increased poly(ADP-ribosyl)ation of nuclear proteins in Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {1999}, doi = {10.1093/brain/122.2.247}, pmid = {10071053}, url = {https://doi.org/10.1093/brain/122.2.247} } @article{romero1998-9788902, author = {Romero, F. J. and Bosch-Morell, F. and Romero, M. J. and Jareño, E. J. and Romero, B. and Marín, N. and Romá, J.}, title = {{Lipid peroxidation products and antioxidants in human disease}}, journal = {Environmental health perspectives}, year = {1998}, doi = {10.1289/ehp.98106s51229}, pmid = {9788902}, url = {https://doi.org/10.1289/ehp.98106s51229} } @article{davey1998-9582300, author = {Davey, Gavin P. and Peuchen, Stefan and Clark, J. B.}, title = {{Energy Thresholds in Brain Mitochondria}}, journal = {Journal of Biological Chemistry}, year = {1998}, doi = {10.1074/jbc.273.21.12753}, pmid = {9582300}, url = {https://doi.org/10.1074/jbc.273.21.12753} } @article{miller1998-29090819, author = {Miller, Diane B. and Ali, Syed F. and O'Callaghan, James Patrick and Laws, Susan C.}, title = {{The Impact of Gender and Estrogen on Striatal Dopaminergic Neurotoxicity}}, journal = {Annals of the New York Academy of Sciences}, year = {1998}, doi = {10.1111/j.1749-6632.1998.tb08230.x}, pmid = {29090819}, url = {https://doi.org/10.1111/j.1749-6632.1998.tb08230.x} } @article{mattson1997-9335256, author = {Mattson, Mark P. and Goodman, Yadong and Luo, Hong and Fu, Weiming and Furukawa, Katsutoshi}, title = {{Activation of NF-?B protects hippocampal neurons against oxidative stress-induced apoptosis: Evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration}}, journal = {Journal of Neuroscience Research}, year = {1997}, doi = {10.1002/(sici)1097-4547(19970915)49:6<681::aid-jnr3>3.0.co;2-3}, pmid = {9335256}, url = {https://doi.org/10.1002/(sici)1097-4547(19970915)49:6<681::aid-jnr3>3.0.co;2-3} } @article{kruman1997-9185546, author = {Kruman, I. and Bruce-Keller, A. J. and Bredesen, D. and Waeg, G. and Mattson, M. P.}, title = {{Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {1997}, doi = {10.1523/jneurosci.17-13-05089.1997}, pmid = {9185546}, url = {https://doi.org/10.1523/jneurosci.17-13-05089.1997} } @article{keller1997-9202320, author = {Keller, Jeffrey N. and Pang, Zheng and Geddes, James W. and Begley, James G. and Germeyer, Ariane and Waeg, Georg and Mattson, Mark P.}, title = {{Impairment of Glucose and Glutamate Transport and Induction of Mitochondrial Oxidative Stress and Dysfunction in Synaptosomes by Amyloid β‐Peptide: Role of the Lipid Peroxidation Product 4‐Hydroxynonenal}}, journal = {Journal of Neurochemistry}, year = {1997}, doi = {10.1046/j.1471-4159.1997.69010273.x}, pmid = {9202320}, url = {https://doi.org/10.1046/j.1471-4159.1997.69010273.x} } @article{sayre1997-9109537, author = {Sayre, L. M. and Zelasko, D. A. and Harris, P. L. and Perry, G. and Salomon, R. G. and Smith, M. A.}, title = {{4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease}}, journal = {Journal of neurochemistry}, year = {1997}, doi = {10.1046/j.1471-4159.1997.68052092.x}, pmid = {9109537}, url = {https://doi.org/10.1046/j.1471-4159.1997.68052092.x} } @article{smith1997-9092586, author = {Smith, M. A. and Richey Harris, P. L. and Sayre, L. M. and Beckman, J. S. and Perry, G.}, title = {{Widespread peroxynitrite-mediated damage in Alzheimer's disease}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {1997}, doi = {10.1523/jneurosci.17-08-02653.1997}, pmid = {9092586}, url = {https://doi.org/10.1523/jneurosci.17-08-02653.1997} } @article{erickson1997-9006971, author = {Erickson, J. C. and Hollopeter, G. and Thomas, S. A. and Froelick, G. J. and Palmiter, R. D.}, title = {{Disruption of the metallothionein-III gene in mice: analysis of brain zinc, behavior, and neuron vulnerability to metals, aging, and seizures}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {1997}, doi = {10.1523/jneurosci.17-04-01271.1997}, pmid = {9006971}, url = {https://doi.org/10.1523/jneurosci.17-04-01271.1997} } @article{simonian1996-8725383, author = {Simonian, N. A. and Coyle, J. T.}, title = {{Oxidative stress in neurodegenerative diseases}}, journal = {Annual review of pharmacology and toxicology}, year = {1996}, doi = {10.1146/annurev.pa.36.040196.000503}, pmid = {8725383}, url = {https://doi.org/10.1146/annurev.pa.36.040196.000503} } @article{hensley1995-7595501, author = {Hensley, K. and Hall, N. and Subramaniam, R. and Cole, P. and Harris, M. and Aksenov, M. and Aksenova, M. and Gabbita, S. P. and others}, title = {{Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation}}, journal = {Journal of neurochemistry}, year = {1995}, doi = {10.1046/j.1471-4159.1995.65052146.x}, pmid = {7595501}, url = {https://doi.org/10.1046/j.1471-4159.1995.65052146.x} } @article{beal1995-7668820, author = {Beal, M. F.}, title = {{Aging, energy, and oxidative stress in neurodegenerative diseases}}, journal = {Annals of neurology}, year = {1995}, doi = {10.1002/ana.410380304}, pmid = {7668820}, url = {https://doi.org/10.1002/ana.410380304} } @article{schipper1995-7778849, author = {Schipper, H. M. and Cissé, S. and Stopa, E. G.}, title = {{Expression of heme oxygenase-1 in the senescent and Alzheimer-diseased brain}}, journal = {Annals of neurology}, year = {1995}, doi = {10.1002/ana.410370609}, pmid = {7778849}, url = {https://doi.org/10.1002/ana.410370609} } @article{mecocci1994-7979220, author = {Mecocci, P. and MacGarvey, U. and Beal, M. F.}, title = {{Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease}}, journal = {Annals of neurology}, year = {1994}, doi = {10.1002/ana.410360510}, pmid = {7979220}, url = {https://doi.org/10.1002/ana.410360510} } @article{dykens1994-8035183, author = {Dykens, James A.}, title = {{Isolated Cerebral and Cerebellar Mitochondria Produce Free Radicals when Exposed to Elevated Ca2+ and Na+: Implications for Neurodegeneration}}, journal = {Journal of Neurochemistry}, year = {1994}, doi = {10.1046/j.1471-4159.1994.63020584.x}, pmid = {8035183}, url = {https://doi.org/10.1046/j.1471-4159.1994.63020584.x} } @article{parker1994-8208407, author = {Parker, William Davis and Parks, Janice K. and Filley, Christopher Mark and Kleinschmidt-DeMasters, Bette Kay}, title = {{Electron transport chain defects in Alzheimer's disease brain}}, journal = {Neurology}, year = {1994}, doi = {10.1212/wnl.44.6.1090}, pmid = {8208407}, url = {https://doi.org/10.1212/wnl.44.6.1090} } @article{behl1994-8004671, author = {Behl, C. and Davis, J. B. and Lesley, R. and Schubert, D.}, title = {{Hydrogen peroxide mediates amyloid beta protein toxicity}}, journal = {Cell}, year = {1994}, doi = {10.1016/0092-8674(94)90131-7}, pmid = {8004671}, url = {https://doi.org/10.1016/0092-8674(94)90131-7} } @article{evans1993-8221024, author = {Evans, P. H.}, title = {{Free radicals in brain metabolism and pathology}}, journal = {British medical bulletin}, year = {1993}, doi = {10.1093/oxfordjournals.bmb.a072632}, pmid = {8221024}, url = {https://doi.org/10.1093/oxfordjournals.bmb.a072632} } @article{heyes1992-1422788, author = {Heyes, M. P. and Saito, K. and Crowley, J. S. and Davis, L. E. and Demitrack, M. A. and Der, M. and Dilling, L. A. and Elia, J. and others}, title = {{Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease}}, journal = {Brain : a journal of neurology}, year = {1992}, doi = {10.1093/brain/115.5.1249}, pmid = {1422788}, url = {https://doi.org/10.1093/brain/115.5.1249} } @article{wallace1992-1533953, author = {Wallace, D. C.}, title = {{Mitochondrial genetics: a paradigm for aging and degenerative diseases?}}, journal = {Science (New York, N.Y.)}, year = {1992}, doi = {10.1126/science.1533953}, pmid = {1533953}, url = {https://doi.org/10.1126/science.1533953} } @article{beal1992-1349466, author = {Beal, M. F.}, title = {{Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?}}, journal = {Annals of neurology}, year = {1992}, doi = {10.1002/ana.410310202}, pmid = {1349466}, url = {https://doi.org/10.1002/ana.410310202} } @article{parker1990-2166249, author = {Parker, William Davis and Filley, Christopher Mark and Parks, Janice K.}, title = {{Cytochrome oxidase deficiency in Alzheimer's disease}}, journal = {Neurology}, year = {1990}, doi = {10.1212/wnl.40.8.1302}, pmid = {2166249}, url = {https://doi.org/10.1212/wnl.40.8.1302} } @article{holt1990-2137962, author = {Holt, I. J. and Harding, A. E. and Petty, R. K. and Morgan-Hughes, J. A.}, title = {{A new mitochondrial disease associated with mitochondrial DNA heteroplasmy}}, journal = {American journal of human genetics}, year = {1990}, pmid = {2137962} } @article{zemlan1989-2521568, author = {Zemlan, F. P. and Thienhaus, O. J. and Bosmann, H. B.}, title = {{Superoxide dismutase activity in Alzheimer's disease: possible mechanism for paired helical filament formation}}, journal = {Brain research}, year = {1989}, doi = {10.1016/0006-8993(89)91550-3}, pmid = {2521568}, url = {https://doi.org/10.1016/0006-8993(89)91550-3} }