% alzhub.org topic: antisense-oligonucleotide % Source: https://alzhub.org/topic/antisense-oligonucleotide % 16 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{chen2025-40339155, author = {Chen, X. Q. and Zuo, X. and Becker, A. and Mante, M. and Florio, J. B. and Jadhav, S. G. and Albay, R. and Johnstone, A. and others}, title = {{Antisense oligonucleotides directed against App and Rab5 normalized endosomal Rab activity and reversed DS-AD-linked degenerative phenotypes in the Dp16 mouse model of Down syndrome}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.70022}, pmid = {40339155}, url = {https://doi.org/10.1002/alz.70022} } @article{ahammad2025-40556661, author = {Ahammad, R. U. and Spencer, B. and Quach, B. and Salehi, S. and Rissman, R. A.}, title = {{A splice-switching antisense oligonucleotide targeting APP reduces accumulation of α-synuclein in a mouse model of Parkinson's disease}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2025}, doi = {10.1002/trc2.70117}, pmid = {40556661}, url = {https://doi.org/10.1002/trc2.70117} } @article{iwataendo2025-40206658, author = {Iwata-Endo, K. and Sahashi, K. and Kawai, K. and Fujioka, Y. and Okada, Y. and Watanabe, E. and Iwade, N. and Ishibashi, M. and others}, title = {{Correcting tau isoform ratios with a long-acting antisense oligonucleotide alleviates 4R-tauopathy phenotypes}}, journal = {Molecular therapy. Nucleic acids}, year = {2025}, doi = {10.1016/j.omtn.2025.102503}, pmid = {40206658}, url = {https://doi.org/10.1016/j.omtn.2025.102503} } @article{rothstein2023-38019311, author = {Rothstein, J. D. and Baskerville, V. and Rapuri, S. and Mehlhop, E. and Jafar-Nejad, P. and Rigo, F. and Bennett, F. and Mizielinska, S. and others}, title = {{G2C4 targeting antisense oligonucleotides potently mitigate TDP-43 dysfunction in human C9orf72 ALS/FTD induced pluripotent stem cell derived neurons}}, journal = {Acta neuropathologica}, year = {2023}, doi = {10.1007/s00401-023-02652-3}, pmid = {38019311}, url = {https://doi.org/10.1007/s00401-023-02652-3} } @article{leitao2023-37690676, author = {Leitão, A. D. G. and Ahammad, R. U. and Spencer, B. and Wu, C. and Masliah, E. and Rissman, R. A.}, title = {{Novel systemic delivery of a peptide-conjugated antisense oligonucleotide to reduce α-synuclein in a mouse model of Alzheimer's disease}}, journal = {Neurobiology of disease}, year = {2023}, doi = {10.1016/j.nbd.2023.106285}, pmid = {37690676}, url = {https://doi.org/10.1016/j.nbd.2023.106285} } @article{monine2021-33991294, author = {Monine, M. and Norris, D. and Wang, Y. and Nestorov, I.}, title = {{A physiologically-based pharmacokinetic model to describe antisense oligonucleotide distribution after intrathecal administration}}, journal = {Journal of pharmacokinetics and pharmacodynamics}, year = {2021}, doi = {10.1007/s10928-021-09761-0}, pmid = {33991294}, url = {https://doi.org/10.1007/s10928-021-09761-0} } @article{chang2018-29628304, author = {Chang, J. L. and Hinrich, A. J. and Roman, B. and Norrbom, M. and Rigo, F. and Marr, R. A. and Norstrom, E. M. and Hastings, M. L.}, title = {{Targeting Amyloid-β Precursor Protein, APP, Splicing with Antisense Oligonucleotides Reduces Toxic Amyloid-β Production}}, journal = {Molecular therapy : the journal of the American Society of Gene Therapy}, year = {2018}, doi = {10.1016/j.ymthe.2018.02.029}, pmid = {29628304}, url = {https://doi.org/10.1016/j.ymthe.2018.02.029} } @article{farr2016-27589526, author = {Farr, S. A. and Sandoval, K. E. and Niehoff, M. L. and Witt, K. A. and Kumar, V. B. and Morley, J. E.}, title = {{Peripheral Administration of GSK-3β Antisense Oligonucleotide Improves Learning and Memory in SAMP8 and Tg2576 Mouse Models of Alzheimer's Disease}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2016}, doi = {10.3233/jad-160416}, pmid = {27589526}, url = {https://doi.org/10.3233/jad-160416} } @article{magner2015-26544037, author = {Magner, D. and Biala, E. and Lisowiec-Wachnicka, J. and Kierzek, E. and Kierzek, R.}, title = {{A Tandem Oligonucleotide Approach for SNP-Selective RNA Degradation Using Modified Antisense Oligonucleotides}}, journal = {PloS one}, year = {2015}, doi = {10.1371/journal.pone.0142139}, pmid = {26544037}, url = {https://doi.org/10.1371/journal.pone.0142139} } @article{jan2015-25957561, author = {Jan, A. and Karasinska, J. M. and Kang, M. H. and de Haan, W. and Ruddle, P. and Kaur, A. and Connolly, C. and Leavitt, B. R. and others}, title = {{Direct intracerebral delivery of a miR-33 antisense oligonucleotide into mouse brain increases brain ABCA1 expression. [Corrected]}}, journal = {Neuroscience letters}, year = {2015}, doi = {10.1016/j.neulet.2015.05.007}, pmid = {25957561}, url = {https://doi.org/10.1016/j.neulet.2015.05.007} } @article{riboldi2014-24809691, author = {Riboldi, G. and Zanetta, C. and Ranieri, M. and Nizzardo, M. and Simone, C. and Magri, F. and Bresolin, N. and Comi, G. P. and others}, title = {{Antisense oligonucleotide therapy for the treatment of C9ORF72 ALS/FTD diseases}}, journal = {Molecular neurobiology}, year = {2014}, doi = {10.1007/s12035-014-8724-7}, pmid = {24809691}, url = {https://doi.org/10.1007/s12035-014-8724-7} } @article{farr2014-24577464, author = {Farr, S. A. and Erickson, M. A. and Niehoff, M. L. and Banks, W. A. and Morley, J. E.}, title = {{Central and peripheral administration of antisense oligonucleotide targeting amyloid-β protein precursor improves learning and memory and reduces neuroinflammatory cytokines in Tg2576 (AβPPswe) mice}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2014}, doi = {10.3233/jad-131883}, pmid = {24577464}, url = {https://doi.org/10.3233/jad-131883} } @article{erickson2012-22179572, author = {Erickson, M. A. and Niehoff, M. L. and Farr, S. A. and Morley, J. E. and Dillman, L. A. and Lynch, K. M. and Banks, W. A.}, title = {{Peripheral administration of antisense oligonucleotides targeting the amyloid-β protein precursor reverses AβPP and LRP-1 overexpression in the aged SAMP8 mouse brain}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2012}, doi = {10.3233/jad-2011-111517}, pmid = {22179572}, url = {https://doi.org/10.3233/jad-2011-111517} } @article{benson2010-20462362, author = {Benson, M. D. and Smith, R. A. and Hung, G. and Kluve-Beckerman, B. and Showalter, A. D. and Sloop, K. W. and Monia, B. P.}, title = {{Suppression of choroid plexus transthyretin levels by antisense oligonucleotide treatment}}, journal = {Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis}, year = {2010}, doi = {10.3109/13506129.2010.483121}, pmid = {20462362}, url = {https://doi.org/10.3109/13506129.2010.483121} } @article{poon2005-15932783, author = {Poon, H. F. and Farr, S. A. and Banks, W. A. and Pierce, W. M. and Klein, J. B. and Morley, J. E. and Butterfield, D. A.}, title = {{Proteomic identification of less oxidized brain proteins in aged senescence-accelerated mice following administration of antisense oligonucleotide directed at the Abeta region of amyloid precursor protein}}, journal = {Brain research. Molecular brain research}, year = {2005}, doi = {10.1016/j.molbrainres.2005.02.020}, pmid = {15932783}, url = {https://doi.org/10.1016/j.molbrainres.2005.02.020} } @article{majocha1994-7621505, author = {Majocha, R. E. and Agrawal, S. and Tang, J. Y. and Humke, E. W. and Marotta, C. A.}, title = {{Modulation of the PC12 cell response to nerve growth factor by antisense oligonucleotide to amyloid precursor protein}}, journal = {Cellular and molecular neurobiology}, year = {1994}, doi = {10.1007/bf02088829}, pmid = {7621505}, url = {https://doi.org/10.1007/bf02088829} }