@article{possemis2024-38438923, author = {Possemis, Nina and Verhey, Frans and Prickaerts, Jos and Blokland, Arjan and Ramakers, Inez}, title = {{A proof of concept phase II study with the PDE-4 inhibitor roflumilast in patients with mild cognitive impairment or mild Alzheimer's disease dementia (ROMEMA): study protocol of a double-blind, randomized, placebo-controlled, between-subjects trial}}, journal = {Trials}, year = {2024}, doi = {10.1186/s13063-024-08001-3}, pmid = {38438923}, url = {https://doi.org/10.1186/s13063-024-08001-3} }