% alzhub.org library filter % Source: https://alzhub.org/research?journal=Science+translational+medicine % 56 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{sanchez2021-33472953, author = {Sanchez, J. S. and Becker, J. A. and Jacobs, H. I. L. and Hanseeuw, B. J. and Jiang, S. and Schultz, A. P. and Properzi, M. J. and Katz, SR. and others}, title = {{The cortical origin and initial spread of medial temporal tauopathy in Alzheimer's disease assessed with positron emission tomography}}, journal = {Science translational medicine}, year = {2021}, doi = {10.1126/scitranslmed.abc0655}, pmid = {33472953}, url = {https://doi.org/10.1126/scitranslmed.abc0655} } @article{roemercassiano2025-39841807, author = {Roemer-Cassiano, S. N. and Wagner, F. and Evangelista, L. and Rauchmann, B. S. and Dehsarvi, A. and Steward, A. and Dewenter, A. and Biel, D. and Zhu, Z. and Pescoller, J. and Gross, M. and Perneczky, R. and others}, title = {{Amyloid-associated hyperconnectivity drives tau spread across connected brain regions in Alzheimer's disease}}, journal = {Science Translational Medicine}, year = {2025}, doi = {10.1126/scitranslmed.adp2564}, pmid = {39841807}, url = {https://doi.org/10.1126/scitranslmed.adp2564} } @article{brier2016-27169802, author = {Brier, M. R. and Gordon, B. and Friedrichsen, K. and McCarthy, J. and Stern, A. and Christensen, J. and Owen, C. and Aldea, P. and others}, title = {{Tau and Aβ imaging, CSF measures, and cognition in Alzheimer's disease}}, journal = {Science translational medicine}, year = {2016}, doi = {10.1126/scitranslmed.aaf2362}, pmid = {27169802}, url = {https://doi.org/10.1126/scitranslmed.aaf2362} } @article{fagan2014-24598588, author = {Fagan, A. M. and Xiong, C. and Jasielec, M. S. and Bateman, R. J. and Goate, A. M. and Benzinger, T. L. and Ghetti, B. and Martins, R. N. and others}, title = {{Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease}}, journal = {Science translational medicine}, year = {2014}, doi = {10.1126/scitranslmed.3007901}, pmid = {24598588}, url = {https://doi.org/10.1126/scitranslmed.3007901} } @article{lajoie2020-31894103, author = {La Joie, R. and Visani, A. V. and Baker, S. L. and Brown, J. A. and Bourakova, V. and Cha, J. and Chaudhary, K. and Edwards, L. and others}, title = {{Prospective longitudinal atrophy in Alzheimer's disease correlates with the intensity and topography of baseline tau-PET}}, journal = {Science translational medicine}, year = {2020}, doi = {10.1126/scitranslmed.aau5732}, pmid = {31894103}, url = {https://doi.org/10.1126/scitranslmed.aau5732} } @article{ferreiro2023-37315112, author = {Ferreiro, A. L. and Choi, J. and Ryou, J. and Newcomer, E. P. and Thompson, R. and Bollinger, R. M. and Hall-Moore, C. and Ndao, I. M. and others}, title = {{Gut microbiome composition may be an indicator of preclinical Alzheimer's disease}}, journal = {Science translational medicine}, year = {2023}, doi = {10.1126/scitranslmed.abo2984}, pmid = {37315112}, url = {https://doi.org/10.1126/scitranslmed.abo2984} } @article{kleinberger2014-24990881, author = {Kleinberger, G. and Yamanishi, Y. and Suárez-Calvet, M. and Czirr, E. and Lohmann, E. and Cuyvers, E. and Struyfs, H. and Pettkus, N. and others}, title = {{TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis}}, journal = {Science translational medicine}, year = {2014}, doi = {10.1126/scitranslmed.3009093}, pmid = {24990881}, url = {https://doi.org/10.1126/scitranslmed.3009093} } @article{castellano2011-21715678, author = {Castellano, Joseph M. and Kim, Jungsu and Stewart, Floy R. and Jiang, Hong and Demattos, Ronald Bradley and Patterson, Bruce W. and Fagan, Anne M. and Morris, John C. and Mawuenyega, Kwasi G. and Cruchaga, Carlos C and Goate, Alison and Bales, Kelly R. and Paul, Steven M. and Bateman, Randall John and Holtzman, David M.}, title = {{Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance}}, journal = {Science Translational Medicine}, year = {2011}, doi = {10.1126/scitranslmed.3002156}, pmid = {21715678}, url = {https://doi.org/10.1126/scitranslmed.3002156} } @article{holtzman2011-21471435, author = {Holtzman, D. M. and Morris, J. C. and Goate, A. M.}, title = {{Alzheimer's disease: the challenge of the second century}}, journal = {Science translational medicine}, year = {2011}, doi = {10.1126/scitranslmed.3002369}, pmid = {21471435}, url = {https://doi.org/10.1126/scitranslmed.3002369} } @article{xiang2021-34644146, author = {Xiang, X. and Wind, K. and Wiedemann, T. and Blume, T. and Shi, Y. and Briel, N. and Beyer, L. and Biechele, G. and others}, title = {{Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases}}, journal = {Science translational medicine}, year = {2021}, doi = {10.1126/scitranslmed.abe5640}, pmid = {34644146}, url = {https://doi.org/10.1126/scitranslmed.abe5640} } @article{iliff2012-22896675, author = {Iliff, Jeffrey J. and Wang, Minghuan and Liao, Yonghong and Plogg, Benjamin A. and Peng, Weiguo and Gundersen, Georg Andreas and Benveniste, Helene and Vates, George Edward and Deane, Rashid and Goldman, Steven A. and Nagelhus, Erlend Arnulf and Nedergaard, Maiken}, title = {{A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β}}, journal = {Science Translational Medicine}, year = {2012}, doi = {10.1126/scitranslmed.3003748}, pmid = {22896675}, url = {https://doi.org/10.1126/scitranslmed.3003748} } @article{sperling2014-24648338, author = {Sperling, R. A. and Rentz, D. M. and Johnson, K. A. and Karlawish, J. and Donohue, M. and Salmon, D. P. and Aisen, P.}, title = {{The A4 study: stopping AD before symptoms begin?}}, journal = {Science translational medicine}, year = {2014}, doi = {10.1126/scitranslmed.3007941}, pmid = {24648338}, url = {https://doi.org/10.1126/scitranslmed.3007941} } @article{suarezcalvet2016-27974666, author = {Suárez-Calvet, M. and MÁ, Araque Caballero and Kleinberger, G. and Bateman, R. J. and Fagan, A. M. and Morris, J. C. and Levin, J. and Danek, A. and others}, title = {{Early changes in CSF sTREM2 in dominantly inherited Alzheimer's disease occur after amyloid deposition and neuronal injury}}, journal = {Science translational medicine}, year = {2016}, doi = {10.1126/scitranslmed.aag1767}, pmid = {27974666}, url = {https://doi.org/10.1126/scitranslmed.aag1767} } @article{sogorbesteve2025-39908349, author = {Sogorb‐Esteve, Aitana and Weiner, Sophia and Simrén, Joel and Swift, Imogen J. and Bocchetta, Martina and Todd, Emily G. and Cash, David M. and Bouzigues, Arabella and others}, title = {{Proteomic analysis reveals distinct cerebrospinal fluid signatures across genetic frontotemporal dementia subtypes}}, journal = {Science Translational Medicine}, year = {2025}, doi = {10.1126/scitranslmed.adm9654}, pmid = {39908349}, url = {https://doi.org/10.1126/scitranslmed.adm9654} } @article{deming2019-31413141, author = {Deming, Y. and Filipello, F. and Cignarella, F. and Cantoni, C. and Hsu, S. and Mikesell, R. and Li, Z. and Del-Aguila, J. L. and others}, title = {{The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk}}, journal = {Science translational medicine}, year = {2019}, doi = {10.1126/scitranslmed.aau2291}, pmid = {31413141}, url = {https://doi.org/10.1126/scitranslmed.aau2291} } @article{sareen2013-24154603, author = {Sareen, D. and O'Rourke, J. G. and Meera, P. and Muhammad, A. K. and Grant, S. and Simpkinson, M. and Bell, S. and Carmona, S. and others}, title = {{Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion}}, journal = {Science translational medicine}, year = {2013}, doi = {10.1126/scitranslmed.3007529}, pmid = {24154603}, url = {https://doi.org/10.1126/scitranslmed.3007529} } @article{ewers2019-31462511, author = {Ewers, M. and Franzmeier, N. and Suárez-Calvet, M. and Morenas-Rodriguez, E. and Caballero, M. A. A. and Kleinberger, G. and Piccio, L. and Cruchaga, C. and others}, title = {{Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease}}, journal = {Science translational medicine}, year = {2019}, doi = {10.1126/scitranslmed.aav6221}, pmid = {31462511}, url = {https://doi.org/10.1126/scitranslmed.aav6221} } @article{sayed2021-34851693, author = {Sayed, F. A. and Kodama, L. and Fan, L. and Carling, G. K. and Udeochu, J. C. and Le, D. and Li, Q. and Zhou, L. and others}, title = {{AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation}}, journal = {Science translational medicine}, year = {2021}, doi = {10.1126/scitranslmed.abe3947}, pmid = {34851693}, url = {https://doi.org/10.1126/scitranslmed.abe3947} } @article{lucey2019-30626715, author = {Lucey, B. P. and McCullough, A. and Landsness, E. C. and Toedebusch, C. D. and McLeland, J. S. and Zaza, A. M. and Fagan, A. M. and McCue, L. and others}, title = {{Reduced non-rapid eye movement sleep is associated with tau pathology in early Alzheimer's disease}}, journal = {Science translational medicine}, year = {2019}, doi = {10.1126/scitranslmed.aau6550}, pmid = {30626715}, url = {https://doi.org/10.1126/scitranslmed.aau6550} } @article{zhao2022-36070367, author = {Zhao, P. and Xu, Y. and Jiang, L. and Fan, X. and Li, L. and Li, X. and Arase, H. and Zhao, Y. and others}, title = {{A tetravalent TREM2 agonistic antibody reduced amyloid pathology in a mouse model of Alzheimer's disease}}, journal = {Science translational medicine}, year = {2022}, doi = {10.1126/scitranslmed.abq0095}, pmid = {36070367}, url = {https://doi.org/10.1126/scitranslmed.abq0095} } @article{sung2023-37406134, author = {Sung, Y. J. and Yang, C. and Norton, J. and Johnson, M. and Fagan, A. and Bateman, R. J. and Perrin, R. J. and Morris, J. C. and others}, title = {{Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer's disease}}, journal = {Science translational medicine}, year = {2023}, doi = {10.1126/scitranslmed.abq5923}, pmid = {37406134}, url = {https://doi.org/10.1126/scitranslmed.abq5923} } @article{cook2020-32878979, author = {Cook, C. N. and Wu, Y. and Odeh, H. M. and Gendron, T. F. and Jansen-West, K. and Del Rosso, G. and Yue, M. and Jiang, P. and others}, title = {{C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy}}, journal = {Science translational medicine}, year = {2020}, doi = {10.1126/scitranslmed.abb3774}, pmid = {32878979}, url = {https://doi.org/10.1126/scitranslmed.abb3774} } @article{davis2020-32024799, author = {Davis, A. A. and Inman, C. E. and Wargel, Z. M. and Dube, U. and Freeberg, B. M. and Galluppi, A. and Haines, J. N. and Dhavale, D. D. and others}, title = {{APOE genotype regulates pathology and disease progression in synucleinopathy}}, journal = {Science translational medicine}, year = {2020}, doi = {10.1126/scitranslmed.aay3069}, pmid = {32024799}, url = {https://doi.org/10.1126/scitranslmed.aay3069} } @article{parhizkar2023-37099634, author = {Parhizkar, S. and Gent, G. and Chen, Y. and Rensing, N. and Gratuze, M. and Strout, G. and Sviben, S. and Tycksen, E. and others}, title = {{Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a TREM2-dependent manner in mice}}, journal = {Science translational medicine}, year = {2023}, doi = {10.1126/scitranslmed.ade6285}, pmid = {37099634}, url = {https://doi.org/10.1126/scitranslmed.ade6285} } @article{guo2026-40949955, author = {Guo, Caiwei and Chen, Kuchuan and Vatsavayai, Sarat C. and Akiyama, Tetsuya and Liu, Chang and Zeng, Yi Bo and Sianto, Odilia and Yang, Edith and others}, title = {{Cryptic splicing in synaptic and membrane excitability genes links TDP-43 loss to neuronal dysfunction}}, journal = {Science Translational Medicine}, year = {2026}, doi = {10.1126/scitranslmed.aeb8517}, pmid = {40949955}, url = {https://doi.org/10.1126/scitranslmed.aeb8517} } @article{lananna2020-33328329, author = {Lananna, B. V. and McKee, C. A. and King, M. W. and Del-Aguila, J. L. and Dimitry, J. M. and Farias, F. H. G. and Nadarajah, C. J. and Xiong, D. D. and others}, title = {{Chi3l1/YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer's disease pathogenesis}}, journal = {Science translational medicine}, year = {2020}, doi = {10.1126/scitranslmed.aax3519}, pmid = {33328329}, url = {https://doi.org/10.1126/scitranslmed.aax3519} } @article{zhou2024-38478630, author = {Zhou, L. and Qiu, X. and Meng, Z. and Liu, T. and Chen, Z. and Zhang, P. and Kuang, H. and Pan, T. and others}, title = {{Hepatic danger signaling triggers TREM2+ macrophage induction and drives steatohepatitis via MS4A7-dependent inflammasome activation}}, journal = {Science translational medicine}, year = {2024}, doi = {10.1126/scitranslmed.adk1866}, pmid = {38478630}, url = {https://doi.org/10.1126/scitranslmed.adk1866} } @article{brandao2025-39813317, author = {Brandão, Wesley Nogueira and Jain, Nimansha and Yin, Zhuoran and Kleemann, Kilian L. and Carpenter, Madison and Bao, Xin and Serrano, Javier Remolina and Tycksen, Eric and others}, title = {{Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy}}, journal = {Science Translational Medicine}, year = {2025}, doi = {10.1126/scitranslmed.adk3690}, pmid = {39813317}, url = {https://doi.org/10.1126/scitranslmed.adk3690} } @article{albanus2025-40737431, author = {Albanus, Ricardo D’Oliveira and Finan, Gina M. and Brase, Logan and Sweeney, Nicholas and Kim, Tae Yeon and Chen, Shuo and Ryoo, Yeonsu and others}, title = {{Systematic analysis of cellular cross-talk reveals a role for SEMA6D-TREM2 regulating microglial function in Alzheimer’s disease}}, journal = {Science Translational Medicine}, year = {2025}, doi = {10.1126/scitranslmed.adx0027}, pmid = {40737431}, url = {https://doi.org/10.1126/scitranslmed.adx0027} } @article{dannert2026-41950304, author = {Dannert, Angelika and Schulz, Nathalie and Klimmt, Julien and Knez, Lea and Groschup, Bernhard and Gonçalves, Carolina Cardoso and Carraro, Caterina and Schifferer, Martina and others}, title = {{A human iPSC model of tauopathies engineered for 4R tau isoform expression endogenously develops late-stage neuronal tau pathology}}, journal = {Science Translational Medicine}, year = {2026}, doi = {10.1126/scitranslmed.adu9845}, pmid = {41950304}, url = {https://doi.org/10.1126/scitranslmed.adu9845} } @article{zhou2023-36989373, author = {Zhou, J. and Wade, S. 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C. and others}, title = {{The neuronal pentraxin Nptx2 regulates complement activity and restrains microglia-mediated synapse loss in neurodegeneration}}, journal = {Science translational medicine}, year = {2023}, doi = {10.1126/scitranslmed.adf0141}, pmid = {36989373}, url = {https://doi.org/10.1126/scitranslmed.adf0141} } @article{chen2025-40305572, author = {Chen, Dadian and Wang, Chen and Chen, Xi and Li, Jiayu and Chen, Shuai and Li, Yanzhong and Ma, Fangling and Li, Tingting and others}, title = {{Brain-wide microglia replacement using a nonconditioning strategy ameliorates pathology in mouse models of neurological disorders}}, journal = {Science translational medicine}, year = {2025}, doi = {10.1126/scitranslmed.ads6111}, pmid = {40305572}, url = {https://doi.org/10.1126/scitranslmed.ads6111} } @article{zhu2024-39475571, author = {Zhu, Biqing and Park, Jae-Min and Coffey, Sarah R and Russo, Anthony and Hsu, I-Uen and Wang, Jiawei and Su, Chang and Chang, Rui and others}, title = {{Single-cell transcriptomic and proteomic analysis of Parkinson's disease brains}}, journal = {Science translational medicine}, year = {2024}, doi = {10.1126/scitranslmed.abo1997}, pmid = {39475571}, url = {https://doi.org/10.1126/scitranslmed.abo1997} } @article{gaikwad2024-38959324, author = {Gaikwad, Sagar and Puangmalai, Nicha and Sonawane, Minal and Montalbano, Mauro and Price, Rachel and Iyer, Malini S and Ray, Anamika and Moreno, Sandra and others}, title = {{Nasal tau immunotherapy clears intracellular tau pathology and improves cognitive functions in aged tauopathy mice}}, journal = {Science translational medicine}, year = {2024}, doi = {10.1126/scitranslmed.adj5958}, pmid = {38959324}, url = {https://doi.org/10.1126/scitranslmed.adj5958} } @article{brennan2024-38865485, author = {Brennan, F. 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K. and Dhaher, R. and Matuskey, D. and others}, title = {{Imaging synaptic density in the living human brain}}, journal = {Science translational medicine}, year = {2016}, doi = {10.1126/scitranslmed.aaf6667}, pmid = {27440727}, url = {https://doi.org/10.1126/scitranslmed.aaf6667} } @article{walker2023-37467317, author = {Walker, Keenan A and Chen, Jingsha and Shi, Liu and Yang, Yunju and Fornage, Myriam and Zhou, Linda and Schlosser, Pascal and Surapaneni, Aditya and others}, title = {{Proteomics analysis of plasma from middle-aged adults identifies protein markers of dementia risk in later life}}, journal = {Science translational medicine}, year = {2023}, doi = {10.1126/scitranslmed.adf5681}, pmid = {37467317}, url = {https://doi.org/10.1126/scitranslmed.adf5681} } @article{silva2026-42616837, author = {Silva, M. 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L. and others}, title = {{MEF2 is a key regulator of cognitive potential and confers resilience to neurodegeneration}}, journal = {Science translational medicine}, year = {2021}, doi = {10.1126/scitranslmed.abd7695}, pmid = {34731014}, url = {https://doi.org/10.1126/scitranslmed.abd7695} } @article{spurrier2022-35648810, author = {Spurrier, J. and Nicholson, L. and Fang, X. T. and Stoner, A. J. and Toyonaga, T. and Holden, D. and Siegert, T. R. and Laird, W. and others}, title = {{Reversal of synapse loss in Alzheimer mouse models by targeting mGluR5 to prevent synaptic tagging by C1Q}}, journal = {Science translational medicine}, year = {2022}, doi = {10.1126/scitranslmed.abi8593}, pmid = {35648810}, url = {https://doi.org/10.1126/scitranslmed.abi8593} } @article{mann2022-35171651, author = {Mann, C. N. and Devi, S. S. and Kersting, C. T. and Bleem, A. V. and Karch, C. M. and Holtzman, D. M. and Gallardo, G.}, title = {{Astrocytic α2-Na+/K+ ATPase inhibition suppresses astrocyte reactivity and reduces neurodegeneration in a tauopathy mouse model}}, journal = {Science translational medicine}, year = {2022}, doi = {10.1126/scitranslmed.abm4107}, pmid = {35171651}, url = {https://doi.org/10.1126/scitranslmed.abm4107} } @article{xiong2021-33597265, author = {Xiong, M. and Jiang, H. and Serrano, JR. and Gonzales, E. R. and Wang, C. and Gratuze, M. and Hoyle, R. and Bien-Ly, N. and others}, title = {{APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function}}, journal = {Science translational medicine}, year = {2021}, doi = {10.1126/scitranslmed.abd7522}, pmid = {33597265}, url = {https://doi.org/10.1126/scitranslmed.abd7522} } @article{ayalon2021-33980574, author = {Ayalon, G. and Lee, S. H. and Adolfsson, O. and Foo-Atkins, C. and Atwal, J. 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