% alzhub.org library filter % Source: https://alzhub.org/research?journal=Research+square % 247 entries, in the order the page lists them. Built from alzhub.org's own records. % 1 entries have no readable author in the source record and carry no author field. @article{song2026-c369392a, author = {Song, Z. and Song, S. and Clare, I. C. and Head, E. and Hom, C. L. and Brickman, A. M. and Hartley, S. and Lao, P. J. and others}, title = {{Multi-dimensional attention framework for personalised Alzheimer's disease progression prediction across sporadic and genetic risk cohorts}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10309496/v1}, url = {https://doi.org/10.21203/rs.3.rs-10309496/v1} } @article{cruchaga2021-91194d89, author = {Cruchaga, C. and Sung, Y. J. and Yang, C. and Wang, F. and Suhy, A. and Norton, J. and Novotny, B. and Etelleb, A. and others}, title = {{Multi-tissue proteomics identifies molecular signatures for sporadic and genetically defined Alzheimer disease cases}}, journal = {Research Square}, year = {2021}, doi = {10.21203/rs.3.rs-923492/v1}, url = {https://doi.org/10.21203/rs.3.rs-923492/v1} } @article{taylor2026-9c23dcf2, author = {Taylor, J. and Alam, J. J. and Gomperts, S. N. and Honig, L. S. and Prins, N. D. and Koubiyr, I. and Chu, H. and Gardner, A. and others}, title = {{A Phase 2b randomized clinical trial of the oral p38α inhibitor neflamapimod in dementia with Lewy bodies (DLB)}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10623740/v1}, url = {https://doi.org/10.21203/rs.3.rs-10623740/v1} } @article{zhong2026-6f685015, author = {ZHONG, M.}, title = {{Application of Plasma Neuron-Derived Exosome-Based Multimodal Biomarkers in the Early Diagnosis of Alzheimer's Disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-9319300/v1}, url = {https://doi.org/10.21203/rs.3.rs-9319300/v1} } @article{joshi2025-40585273, author = {Joshi, Aparna and Chang, Jun Ha and Basulto-Elias, Guillermo and Hallmark, Shauna and Rizzo, Matthew and Sharma, Anuj}, title = {{Identifying and Predicting Cognitive Decline Using Multi-Modal Sensor Data and Machine Learning Approach}}, journal = {Research square}, year = {2025}, doi = {10.21203/rs.3.rs-6735622/v1}, pmid = {40585273}, url = {https://doi.org/10.21203/rs.3.rs-6735622/v1} } @article{chen2024-39764106, author = {Chen, Jingchun and Cammann, Davis and Liu, Tingwei and Liu, Yimei and Cummings, Melika and Chen, Xiangning and Oh, Edwin and Rotter, Jerome}, title = {{Shared Genetic Architecture Between COVID-19 Severity and Alzheimer's Disease Across European and African Ancestries}}, journal = {Research square}, year = {2024}, doi = {10.21203/rs.3.rs-5619229/v1}, pmid = {39764106}, url = {https://doi.org/10.21203/rs.3.rs-5619229/v1} } @article{cheng2024-39184089, author = {Cheng, Feixiong and Feng, Yayan and Flanagan, Margaret and Bonakdarpour, Borna and Jamshidi, Pouya and Castellani, Rudolph and Mao, Qinwen and Chu, Xiaona and others}, title = {{Single-nucleus multiome analysis of human cerebellum in Alzheimer's disease-related dementia}}, journal = {Research square}, year = {2024}, doi = {10.21203/rs.3.rs-4871032/v1}, pmid = {39184089}, url = {https://doi.org/10.21203/rs.3.rs-4871032/v1} } @article{senapati2025-41377958, author = {Senapati, Sudipta and Sciortino, Alessia and Samples, Madison and Shchankin, Nikita and Zhao, Yingxin and Montalbano, Mauro and Kayed, Rakez}, title = {{Human Wild-Type α-Synuclein Drives Progressive Tau Pathology in a Disease-Relevant Mouse Model of Synucleinopathy}}, journal = {Research square}, year = {2025}, doi = {10.21203/rs.3.rs-8166445/v1}, pmid = {41377958}, url = {https://doi.org/10.21203/rs.3.rs-8166445/v1} } @article{mcdade2024-39108475, author = {McDade, Eric and Liu, Haiyan and Bui, Quoc and Hassenstab, Jason and Gordon, Brian and Benzinger, Tammie and Shen, Yuanyuan and Timsina, Jigyasha and others}, title = {{Ubiquitin-Proteasome System in the Different Stages of Dominantly Inherited Alzheimer's Disease}}, journal = {Research square}, year = {2024}, doi = {10.21203/rs.3.rs-4202125/v1}, pmid = {39108475}, url = {https://doi.org/10.21203/rs.3.rs-4202125/v1} } @article{koivumaki2026-19abfe03, author = {Koivumäki, M. and Snellman, A. and Ekblad, L. and Benedet, A. and Zetterberg, H. and Rinne, J.}, title = {{Longitudinal plasma biomarkers and multimodal PET across APOE ε4 genotypes: a prospective cohort study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11294615/v1}, url = {https://doi.org/10.21203/rs.3.rs-11294615/v1} } @article{hou2026-a6466441, author = {Hou, T. and Wei, Q. and Shi, L. and Liu, C. and Zhu, M. and Tian, X. and Zhang, H. and Tian, N. and others}, title = {{Associations of genetic predisposition to Alzheimer’s disease with blood-based biomarkers: a community-based study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11220681/v1}, url = {https://doi.org/10.21203/rs.3.rs-11220681/v1} } @article{rodriguezespinosa2026-415c6827, author = {Rodriguez-Espinosa, N.}, title = {{Soluble amyloid composition links proximal APP processing, fibrillar burden and the p-tau181 response}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10955863/v1}, url = {https://doi.org/10.21203/rs.3.rs-10955863/v1} } @article{i2026-af4554ea, author = {Í, Rodríguez-Baz and Ferrer, R. and Falip, M. S. and Vera-Campuzano, E. and Sala, I. and Maure-Blesa, L. and Selma-González, J. and García-Castro, J. and others}, title = {{α-Synuclein Seed Amplification Status Modifies the Relationship Between Plasma p-tau217, Amyloid and Fibrillar Tau}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11271891/v1}, url = {https://doi.org/10.21203/rs.3.rs-11271891/v1} } @article{gao2026-cac95d7a, author = {Gao, P. and Tan, H. and Li, G. and Liang, J. and Yang, M. and Xu, D. and Wang, Q. and Liang, S. and others}, title = {{Basal Ganglia Iron Accumulation Mediates Stage-Dependent Associations Between Plasma pTau217 and Hippocampal Atrophy in Alzheimer’s Disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11017150/v1}, url = {https://doi.org/10.21203/rs.3.rs-11017150/v1} } @article{chen2026-e0e0d44c, author = {Chen, Z. and Lin, F. and Yang, K. and Tang, W. and Li, J. and Niu, J. and Shi, Y. and Zhou, S. and others}, title = {{Multimodal mediators connecting APOE4 to dementia}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11445203/v1}, url = {https://doi.org/10.21203/rs.3.rs-11445203/v1} } @article{elsalamony2026-a10c51b4, author = {EL-Salamony, G. I. and Mohamed, R. H. and Saad, R. A. and Tarek, M. and Fawzy, N. M. and Elnahas, E. M.}, title = {{Neuroprotective Role of Vitamin D Against LPS-Induced Cognitive Deficits in Rats: Targeting Hippocampal PERK-ATF4-CHOP-Mediated ER Stress and Calcium Dyshomeostasis}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10413434/v1}, url = {https://doi.org/10.21203/rs.3.rs-10413434/v1} } @article{elyasi2026-2817a815, author = {Elyasi, L. and Chołoniewska, A. and Lutostańska, E. and Mierzwa, N. and Sulejczak, D. and Macias, M. and Szybińska, A. and Gawlik-Zawiślak, S. and others}, title = {{SHED-Derived Exosomes Attenuate Alzheimer's Disease Pathology in iPSC-Derived Cerebral Organoid Model}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11225065/v1}, url = {https://doi.org/10.21203/rs.3.rs-11225065/v1} } @article{liu2026-6e29bce4, author = {Liu, X. and Liu, Z. and Lv, Z. and Lei, Y. and Zhou, Z. and Xu, Z. and Duan, J. and Xing, W. and others}, title = {{Mechanistic study of PHLDA1 in cognitive dysfunction of Alzheimer’s disease model mice via FoxO1‑mediated neuroinflammation}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10948741/v1}, url = {https://doi.org/10.21203/rs.3.rs-10948741/v1} } @article{chen2026-074ef6d2, author = {Chen, S. and Wang, M. and Ji, Y.}, title = {{Plasma Fibrinogen Correlates with Aβ Clearance of monocytes and AD Biomarkers in Cognitively Normal Individuals}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10658330/v1}, url = {https://doi.org/10.21203/rs.3.rs-10658330/v1} } @article{bernardi2026-632475b0, author = {Bernardi, E. and Arranz, J. and Rubio-Guerra, S. and García-Castro, J. and Maure-Blesa, L. and Rodríguez-Baz, I. and Peris-Subiza, J. and Selma-González, J. and others}, title = {{Does CSF testing add value after an indeterminate plasma p-tau217 result?}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10754560/v1}, url = {https://doi.org/10.21203/rs.3.rs-10754560/v1} } @article{hey2026-a02492d7, author = {Hey, J. A. and Geerts, H. and Schaefer, J. F. and Short, S. M. and Graaf, P. and Abushakra, S. and Power, A. and Tolar, M. and others}, title = {{Quantitative Systems Pharmacology Analysis of Amyloid Aggregation and Hippocampal Atrophy Trajectories in Alzheimer’s Disease by APOE4 Genotype and Valiltramiprosate/ALZ-801 Treatment}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10570608/v1}, url = {https://doi.org/10.21203/rs.3.rs-10570608/v1} } @article{malotaux2026-6c38e2c0, author = {Malotaux, V. and Tristão-Pereira, C. and Zuluaga, Y. and Munoz, C. and Guerrero, A. and Bocanegra, Y. and Alzate, D. and Serna, L. and others}, title = {{Plasma Biomarker Profiles in a Colombian Cohort of Heterozygous APOE3-Christchurch Carriers}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10705602/v1}, url = {https://doi.org/10.21203/rs.3.rs-10705602/v1} } @article{yan2026-d8ff574a, author = {Yan, J. and Wang, Y. and Han, H. and Zhao, T. and Liu, D. and Chai, T. and Zhou, Y. and Yan, K. and others}, title = {{Diagnostic Concordance Between Plasma p-Tau217 and Amyloid-β Biomarkers in Symptomatic Alzheimer's Disease: Evidence From a Chinese Cohort}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10410778/v1}, url = {https://doi.org/10.21203/rs.3.rs-10410778/v1} } @article{toniolo2026-3b9d2254, author = {Toniolo, S. and Zhao, S. and Broulidakis, M. and Fower, A. and Gendarini, C. and Scholcz, A. and Griffiths, T. and Zetterberg, H. and others}, title = {{Test-retest reliability of plasma biomarkers and digital cognitive metrics at clinically meaningful timescales}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10016306/v1}, url = {https://doi.org/10.21203/rs.3.rs-10016306/v1} } @article{chan2026-7050e06c, author = {Chan, J. W. and Corradetti, G. and Soylu, C. and Almidani, L. and Wu, X. and Wang, Z. C. and Astraea, N. and Hu, Z. and others}, title = {{Neurovascular Outer Retinal Degeneration in Presymptomatic Alzheimer’s Disease: An Oculomic Biomarker Study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10251231/v2}, url = {https://doi.org/10.21203/rs.3.rs-10251231/v2} } @article{perkiomaki2026-fae5adec, author = {Perkiömäki, V. and Raitamaa, L. and Mattila, H. and Elabasy, A. and Huotari, N. and Väyrynen, T. and Tuunanen, J. and Helakari, H. and others}, title = {{Amplitude of physiological brain pulsations in Alzheimer’s disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-9725762/v1}, url = {https://doi.org/10.21203/rs.3.rs-9725762/v1} } @article{gongye2026-01d7a115, author = {Gongye, H. and Wang, F. and Sun, M. and Wang, M.}, title = {{Factors Influencing the Implementation of Computerized Cognitive Training in Chinese Community-Dwelling Elderly: A Qualitative Study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10959058/v1}, url = {https://doi.org/10.21203/rs.3.rs-10959058/v1} } @article{tsujishita2026-568878f1, author = {Tsujishita, S. and Kotani, S. and Otani, Y. and Iwamoto, K. and Iwase, H.}, title = {{Associations between objectively measured smartphone screen time and ikigai in community-dwelling older adults: roles of physical function and social frailty}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10846996/v1}, url = {https://doi.org/10.21203/rs.3.rs-10846996/v1} } @article{chuang2026-fb532b10, author = {Chuang, H. and Hsieh, M. and Huang, C. and Cheng, Y. and Huang, S.}, title = {{Comparative Performance of Conventional, Informant-Based, and Digital Cognitive Screening Tools in Community-Dwelling Older Adults: A Cross-Sectional Study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10608928/v1}, url = {https://doi.org/10.21203/rs.3.rs-10608928/v1} } @article{boekholt2026-dc67c10d, author = {Boekholt, M. and Biernetzky, O. and Thyrian, JR. and Blotenberg, I. and Teipel, S. and Michalowsky, B. and Afrin, D. and Kilimann, I. and others}, title = {{Efficacy of care management in reducing needs of caregivers of people with dementia}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10521194/v1}, url = {https://doi.org/10.21203/rs.3.rs-10521194/v1} } @article{hwang2026-bc771d3f, author = {Hwang, I. C. and Kim, S. H. and Lee, Y. J. and Choi, Y. S. and Ahn, H. Y.}, title = {{Living arrangements shape the determinants of life-sustaining treatment preferences among Korean older adults}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10441296/v1}, url = {https://doi.org/10.21203/rs.3.rs-10441296/v1} } @article{convery2026-51305e03, author = {Convery, R. S. and Adams-Carr, K. and Russell, L. L. and Blesius, A. and Goldsmith, S. and Farley, S. and Ferry-Bolder, E. and Bouzigues, A. and others}, title = {{The Ignite app detects early cognitive impairment and tracks disease severity in genetic frontotemporal dementia}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10304180/v1}, url = {https://doi.org/10.21203/rs.3.rs-10304180/v1} } @article{shen2026-ca8d722a, author = {Shen, J. and Shen, Y. and Yu, G. and Pang, L. and Xiao, C.}, title = {{Structured Metabolic Genetic Axes Reveal Distinct Lipid and Ketone-Body Programs in Alzheimer’s and Parkinson’s Disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11247856/v1}, url = {https://doi.org/10.21203/rs.3.rs-11247856/v1} } @article{williams2026-682e61e2, author = {Williams, G.}, title = {{Disease-Specific Perturbational Convergence Between Genetic-Risk and Disease-State Transcriptomic Signatures in Alzheimer's Disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11315638/v1}, url = {https://doi.org/10.21203/rs.3.rs-11315638/v1} } @article{hwang2026-c2ebe340, author = {Hwang, S.}, title = {{White matter hyperintensities partly mediate genetically predicted blood pressure effects on vascular dementia}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11236498/v1}, url = {https://doi.org/10.21203/rs.3.rs-11236498/v1} } @article{ren2026-b1e4c121, author = {Ren, Y. and He, Z. and Feng, Y. and Wang, R. and Cai, H. and Chen, Q. and Wang, M.}, title = {{Large-Scale Genome-wide association study identified Shared Genetic Risk SNPs Correlates in Epilepsy and Alzheimer's Disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10960127/v1}, url = {https://doi.org/10.21203/rs.3.rs-10960127/v1} } @article{study2026-a7ffdc0c, title = {{Genetically predicted multisite chronic pain is associated with lower cognitive performance: a bidirectional Mendelian randomization study with NHANES contextual evidence}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11103914/v1}, url = {https://doi.org/10.21203/rs.3.rs-11103914/v1} } @article{zott2026-90b7bcf3, author = {Zott, B. and Unger, F. and Wolf, C. and Schlepckow, K. and Ulmer, N. and Rossignol, P. and Pousinha, P. and Chen, L. and others}, title = {{Soluble TREM2 suppresses neuronal activity}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11388834/v1}, url = {https://doi.org/10.21203/rs.3.rs-11388834/v1} } @article{da2026-559eb37f, author = {Da, J. and Zhang, R. and Xu, L. and Wu, R. and Zhang, S. and Wang, H. and Baazaoui, N. and Shi, J. and others}, title = {{NADPH attenuates tau pathology and disease-associated microglial phenotype in a truncated tau- induced mouse model}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11151367/v1}, url = {https://doi.org/10.21203/rs.3.rs-11151367/v1} } @article{tan2026-437238a8, author = {Tan, Q. and Xie, A. and Chen, J. and Wei, S. and Guo, Y. and Liu, G. and Wang, L. and Liu, X. and others}, title = {{Electroacupuncture alleviate cognitive impairment via activation of TREM2-positive microglia in APP/PS1 mice}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11138446/v1}, url = {https://doi.org/10.21203/rs.3.rs-11138446/v1} } @article{kotredes2026-6da14e5f, author = {Kotredes, K. P. and Pandey, R. S. and Reagan, A. M. and Sarica, Z. and O'Rourke, R. and Herrick, S. and Davis, A. and Garceau, D. and others}, title = {{MTHFR*677C>T produces distinct prodromal disease signatures in a mouse model of late-onset Alzheimer’s disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11166891/v1}, url = {https://doi.org/10.21203/rs.3.rs-11166891/v1} } @article{rodriguez2026-ef1dd141, author = {Rodríguez, E. M. and Zaragoza-Ballester, P. and Alcolea, D. and Esteller-Gauxax, D. and Nuscher, B. and Chacón, S. and Á, Fernández-León and Í, Rodríguez-Baz and others}, title = {{APOEε4 attenuates early TREM2-mediated microglial responses and influences disease trajectories in dementia with Lewy bodies}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10429506/v1}, url = {https://doi.org/10.21203/rs.3.rs-10429506/v1} } @article{chen2026-b03c3c29, author = {Chen, X. and Munoz-Mayorga, D. and Lyu, X. and Jati, S. and Zhang, J. and Rossitto, L. and Tao, Y. and Zhao, S. and others}, title = {{A non-canonical androgen signaling pathway drives microglial activation and tau pathology in females}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10286730/v1}, url = {https://doi.org/10.21203/rs.3.rs-10286730/v1} } @article{hemmati2026-4e8ac976, author = {Hemmati, S. and Wang, E. and Wang, M. and Xie, B. and Salton, S. and Haroutunian, V. and Bennett, D. and Xu, P. and others}, title = {{The effects of Arf4 gene knockdown on Alzheimer's amyloid β deposition: Possible role in cognitive resilience}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11040037/v1}, url = {https://doi.org/10.21203/rs.3.rs-11040037/v1} } @article{sv2026-76f5166c, author = {Sv, Westendorp and Hofman, C. and Gerring, P. and Mol, M. and Pontier, P. and Gijsberts, I. and Koopmans, R. and Bakker, C.}, title = {{Person-centred care in the early post-diagnostic phase of young-onset dementia: co-created insights from service users and professionals through participatory action research}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10915497/v1}, url = {https://doi.org/10.21203/rs.3.rs-10915497/v1} } @article{crowe2026-08036707, author = {Crowe, A.}, title = {{Evidence of P-glycoprotein mediated bidirectional transport of beta-amyloid (Ab40 and Ab42) through CLEFF4 cells}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10926932/v1}, url = {https://doi.org/10.21203/rs.3.rs-10926932/v1} } @article{taofeek2026-32f5acbd, author = {Taofeek, O. O. and Adigun, S. A. and Oladipo, E. K. and Mushebenge, A. G. and Khairallah, A. and Akinduti, P. and Sulaimon, L. A.}, title = {{Integrative systems biology identifies shared neuroimmune co-expression programmes across pulmonary tuberculosis and Alzheimer's disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11528962/v1}, url = {https://doi.org/10.21203/rs.3.rs-11528962/v1} } @article{hathi2026-f749be57, author = {Hathi, U. P. S. and Kumar, A. and Arora, J. and Kateriya, S.}, title = {{APH-1A and CDK5 Expression Correlates with Tau Hyperphosphorylation and Its Attenuation by Brahmi and Donep-M in STZ induced Alzheimer’s Disease Model}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11257702/v1}, url = {https://doi.org/10.21203/rs.3.rs-11257702/v1} } @article{lyu2026-d9d173bc, author = {Lyu, J.}, title = {{PIN1-p53 bifurcation dictates opposite cell fate decisions in Alzheimer’s disease and glioblastoma via distinct energy landscape topologies}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11415613/v1}, url = {https://doi.org/10.21203/rs.3.rs-11415613/v1} } @article{armah2026-0dd7e989, author = {Armah, F. and Abor, E. and Sam, P. and Sarpong, E. and Ghartey-Kwansah, G.}, title = {{CausalDiffChem: Causal Network Restoration for Therapeutic Prioritization and Repurposing Across Diseases}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11272130/v1}, url = {https://doi.org/10.21203/rs.3.rs-11272130/v1} } @article{tissot2026-2c13a0a9, author = {Tissot, C. and Tsai, H. and Lee, J. Y. and Rahmouni, N. and Lussier, F. Z. and Fonseca, C. S. and Therriault, J. and Stevenson, J. and others}, title = {{Large-scale head-to-head comparison of on- and off-target profiles of [18F]Tauvid and [18F]MK6240 tau-PET in aging and Alzheimer’s disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-9987995/v1}, url = {https://doi.org/10.21203/rs.3.rs-9987995/v1} } @article{antic2026-8a81da8c, author = {Antic, A. and Dreos, A. and Lashley, T. and Yo-Ap, S. Y. and Sander, K. and Schöll, M. and Hanrieder, J.}, title = {{Second-generation tau PET tracer in situ binding assessed with fluorescence imaging}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11153643/v1}, url = {https://doi.org/10.21203/rs.3.rs-11153643/v1} } @article{bao2026-1e5483ae, author = {Bao, R. and Zhang, S. and Wang, F. and Cheng, W. and Zhang, T. and Ding, W.}, title = {{MRI-derived periventricular diffusivity contextualizes plasma pTau217 associations with Alzheimer pathology: a discovery–validation study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10895317/v1}, url = {https://doi.org/10.21203/rs.3.rs-10895317/v1} } @article{zhang2026-f99a3bc7, author = {Zhang, S. and Bao, R. and He, H. and {Initiative ftADN} and Zhang, T. and Cheng, W. and Ding, W.}, title = {{Clinical expression beyond measured Alzheimer disease molecular pathology: a discovery and external evaluation study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10847343/v1}, url = {https://doi.org/10.21203/rs.3.rs-10847343/v1} } @article{javanray2026-8250ae3c, author = {Javanray, M. and Gallego-Rudolf, J. and Yakoub, Y. and Qiu, T. and St-Onge, F. and Remz, J. and Soucy, J. and Misic, B. and others}, title = {{Network-level functional connectivity is associated with longitudinal tau accumulation and amyloid-dependent cognitive decline in preclinical Alzheimer’s disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10282950/v1}, url = {https://doi.org/10.21203/rs.3.rs-10282950/v1} } @article{nakata2026-6cc54487, author = {Nakata, T. and Shimada, K. and Oda, H. and Terashima, A. and Suenaga, Y. and Kawasaki, R. and Yamada, T. and Ishii, K.}, title = {{Estimating amyloid-β deposition using brain perfusion SPECT in Alzheimer's disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10624411/v1}, url = {https://doi.org/10.21203/rs.3.rs-10624411/v1} } @article{zerrouki2026-2417b906, author = {Zerrouki, H. and Azzaz-Rahmani, S.}, title = {{Multimodal Transformer-Based Fusion of Blood-Based and Digital Biomarkers for Explainable (XAI) Ultra-Early Alzheimer's Disease Detection}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10462750/v1}, url = {https://doi.org/10.21203/rs.3.rs-10462750/v1} } @article{harput2026-7b7b99fe, author = {Harput, E. and Boccalini, C. and Scheffler, M. and Lovblad, K. and Ashton, N. J. and Zetterberg, H. and Hansson, O. and Lalive, H. M. and others}, title = {{Mapping Amyloid-PET Uptake in the White Matter in Alzheimer’s Disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10277565/v1}, url = {https://doi.org/10.21203/rs.3.rs-10277565/v1} } @article{nazeri2026-89aedc92, author = {Nazeri, A. and Hosseini, H. and Sotiras, A. and Sato, C. and Elbert, D. and Yang, B. and Joseph-Mathurin, N. and Ovod, V. and others}, title = {{Regional Cerebrospinal Fluid Motility as a Key Determinant of Soluble Amyloid-β Levels and Kinetics}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10530209/v1}, url = {https://doi.org/10.21203/rs.3.rs-10530209/v1} } @article{falahati2026-fe58168b, author = {Falahati, M. and Ramezannejad, E. and Vaez-Gharamaleki, Y. and Radnia, P. and Shahba, S. and Rasoulian, P. and Rezaei, S. and Dasmeh, N. and others}, title = {{Determining the metabolic profile measured using ultra-high pressure liquid chromatography associated with Beta Amyloid burden in the brain in individuals with mild cognitive impairment}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10065374/v1}, url = {https://doi.org/10.21203/rs.3.rs-10065374/v1} } @article{razzetta2026-539ba847, author = {Razzetta, C. and Garbarino, S.}, title = {{A Wasserstein Weisfeiler-Lehman Kernel Framework for Multimodal Brain Connectome Analysis}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11266269/v1}, url = {https://doi.org/10.21203/rs.3.rs-11266269/v1} } @article{yao2026-d17fad06, author = {Yao, N. and Wang, Z. and Sun, D. and Han, C. and Li, Y. and Nan, J. and Zhu, F. and Zhao, C. and others}, title = {{MVMGNN: Multi-View Masked Graph Neural Network for Alzheimer’s Disease Diagnosis using Structural MRI}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11185794/v1}, url = {https://doi.org/10.21203/rs.3.rs-11185794/v1} } @article{yu2026-3df0a36b, author = {Yu, L. and Meng, M. and Gao, Y. and Xi, X.}, title = {{A Dual-Stream Spatio-Temporal Network with Bidirectional Rectification for Differential Diagnosis of Dementia using EEG}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10724309/v1}, url = {https://doi.org/10.21203/rs.3.rs-10724309/v1} } @article{joshi2026-495ba8c6, author = {Joshi, G.}, title = {{Predictive EEG Signatures of Alzheimer's Disease: A Cross-Validated, Cross-Method Analysis Using ANCOVA Filtering and Sparse Logistic Regression}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11390599/v1}, url = {https://doi.org/10.21203/rs.3.rs-11390599/v1} } @article{rojaspescio2026-f194ed38, author = {Rojas-Pescio, H.}, title = {{Information-Theoretic Geometry HCFIM features for data-limited EEG screening of Alzheimer’s disease and Frontotemporal Dementia}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10834216/v1}, url = {https://doi.org/10.21203/rs.3.rs-10834216/v1} } @article{perovnik2026-b01fe529, author = {Perovnik, M. and Eidelberg, D.}, title = {{Neurodegenerative disorders: Stereotyped relationships between pathological metabolic topographies and the healthy default mode network}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11320531/v1}, url = {https://doi.org/10.21203/rs.3.rs-11320531/v1} } @article{matar2026-939eae22, author = {Matar, E. and Anderson, J. and Churchill, L. and Konuri, A. and Ignatavicius, A. and Cho, G. and Lam, A. and Naismith, S. and others}, title = {{Thalamocortical correlates of sleep spindle and slow oscillation dysfunction in Lewy body disorders}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10904079/v1}, url = {https://doi.org/10.21203/rs.3.rs-10904079/v1} } @article{nago2026-f876eb5b, author = {Nago, B. and Qu, C.}, title = {{Simulating the Effects of Gamma Oscillation Treatment on Selective Neurotransmitters Using The Virtual Brain and Complex Pathway Simulator}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11199141/v2}, url = {https://doi.org/10.21203/rs.3.rs-11199141/v2} } @article{marciniakagra2026-1d9e787e, author = {Marciniak-Agra, K. and Devi, G.}, title = {{Amyloid and Tau Cerebrospinal Fluid Biomarker Normalization in a Patient with Alzheimer’s Disease treated with Lecanemab: A Case Report}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10778388/v1}, url = {https://doi.org/10.21203/rs.3.rs-10778388/v1} } @article{srivastava2026-440c4088, author = {Srivastava, V.}, title = {{Effectiveness of Modern Diagnostic and Therapeutic Interventions for Major Neurological Disorders: A Systematic Literature Review}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10630206/v1}, url = {https://doi.org/10.21203/rs.3.rs-10630206/v1} } @article{morse2026-aa1d8498, author = {Morse, S. V. and Rohfleisch, L. and Geoghegan, G. and Sujarittam, K. and Rimer, S. and Chan, T. G. and Kench, T. and Pereira, M. A. and others}, title = {{Cobalt-Based Drug Delivery to the Brain using Rapid Short-Pulses of Focused Ultrasound and Microbubbles reduces Aβ aggregation in 5XFAD mice}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10332117/v1}, url = {https://doi.org/10.21203/rs.3.rs-10332117/v1} } @article{basile2026-35f2647e, author = {Basile, S. and Schipper, F. and Zimbone, S. and Vermorgen, S. M. and Bellia, F. and Parisi, C. and Sortino, S. and Walter, J. and others}, title = {{Mapping post-translational modifications across amyloid-β deposits in Alzheimer’s disease: A neuropathologic survey with in vitro functional analysis of nitration}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10769225/v1}, url = {https://doi.org/10.21203/rs.3.rs-10769225/v1} } @article{sen2026-0a617270, author = {Sen, S. E.}, title = {{A Simulation-Based Discrete Choice Experiment Framework for Alzheimer’s Disease-Modifying Therapy Implementation: Methodology and Interactive Decision Support Tool}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-9404461/v1}, url = {https://doi.org/10.21203/rs.3.rs-9404461/v1} } @article{sen2026-17588c9d, author = {Sen, S. E.}, title = {{PREFER-DMT: A Discrete Choice Experiment Framework for Eliciting Stakeholder Preferences on Disease-Modifying Therapy Implementation in European Healthcare Systems}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-9405777/v1}, url = {https://doi.org/10.21203/rs.3.rs-9405777/v1} } @article{richardson2026-dfc57a73, author = {Richardson, B. and Casson, A. and Blanford, C. and Gunputh, U.}, title = {{A Proof-of-Concept Graphene-Functionalised Embroidered Textile Biosensing Platform for Salivary Alzheimer's Disease Biomarker Detection}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10535881/v1}, url = {https://doi.org/10.21203/rs.3.rs-10535881/v1} } @article{lehrer2026-830ed5a8, author = {Lehrer, S.}, title = {{Alzheimer's Disease as the Result of Aberrant Reactivation of Embryonic Brain Pathways Silenced Decades Earlier}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10436661/v1}, url = {https://doi.org/10.21203/rs.3.rs-10436661/v1} } @article{karim2026-c556b929, author = {Karim, F. and Biju, A. P. and Liang, C. and Santos, C. J. and Rajarethenam, M. and Mukherjee, J.}, title = {{Evaluation of [18F]MK-6240 binding to tau protein in postmortem human brains of Down syndrome and Alzheimer’s disease and assessment of off-target (non-tau) binding}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-8463304/v1}, url = {https://doi.org/10.21203/rs.3.rs-8463304/v1} } @article{gupta2025-20b76129, author = {GUPTA, A. and Liu, R. and Keely, D. and Sunderman, V. and Tak, Y. and Konstantoulea, K. and Terpack, S. and White, C. L. and others}, title = {{Conformation-based detection of tau seeds with a novel VHH}}, journal = {Research Square}, year = {2025}, doi = {10.21203/rs.3.rs-8274351/v1}, url = {https://doi.org/10.21203/rs.3.rs-8274351/v1} } @article{lehrer2025-eaeb6aee, author = {Lehrer, S.}, title = {{Plasma pTau-181 Exhibits Flat Longitudinal Trajectories and Weak Cognitive Correlation in UK Biobank: Implications for Anti-Tau Antibody Trial Failures}}, journal = {Research Square}, year = {2025}, doi = {10.21203/rs.3.rs-8204349/v1}, url = {https://doi.org/10.21203/rs.3.rs-8204349/v1} } @article{wu2025-293b5940, author = {Wu, H. and Hou, Y. and Feng, X. and Xia, X. and Yu, X. and Kong, W.}, title = {{mRNA vaccine platform demonstrates potent immunotherapeutic targeting of amyloid-β and tau pathologies in Alzheimer's disease}}, journal = {Research Square}, year = {2025}, doi = {10.21203/rs.3.rs-7514957/v1}, url = {https://doi.org/10.21203/rs.3.rs-7514957/v1} } @article{ahmed2026-e5966415, author = {Ahmed, A. and k, Almutari}, title = {{Beyond Cardiology's Pillars: A Network Meta-Analysis Comparing the Recombinant Zoster Vaccine (Shingrix/RZV) with SGLT2 Inhibitors and GLP-1 Receptor Agonists for Prevention of Major Adverse Cardiovascular Events and Dementia in Adults Aged ≥50 Years}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-9727771/v1}, url = {https://doi.org/10.21203/rs.3.rs-9727771/v1} } @article{iftikhar2026-5f7606f8, author = {Iftikhar, H. and Ejaz, M. M. and Al-Namshah, K. S. and Khan, S. and Ashraf, S. and Meer, N. and Riaz, M. and Saleem, M.}, title = {{Natural Sesquiterpenoids from Laggera pterodonta as bioactive Acetylcholinesterase Inhibitors: Insights from DFT, Molecular Docking, and ADMET Profiling}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11218173/v1}, url = {https://doi.org/10.21203/rs.3.rs-11218173/v1} } @article{ejaz2026-f06e02fb, author = {Ejaz, M. M. and Iftikhar, H. and Al-Namshah, K. and Khan, S. and Ashraf, S. and Meer, N. and Riaz, M. and Saleem, M. and others}, title = {{Substituent Effects on Electronic Properties and Acetylcholinesterase Inhibitory Potential of Donepezil Analogues: A DFT, Molecular Docking, and ADMET Study with Dynamics Validation of the Lead Candidate}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11082767/v1}, url = {https://doi.org/10.21203/rs.3.rs-11082767/v1} } @article{dange2026-86ec91fb, author = {Dange¹, R. T. and Jadhav², S. B. and RAj, rupali}, title = {{Docking-Guided Design and Biological Evaluation of a Lead Convolvine-Based Acetylcholinesterase Inhibitor for Alzheimer's Disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10890265/v1}, url = {https://doi.org/10.21203/rs.3.rs-10890265/v1} } @article{rao2026-29a49622, author = {Rao, R. and Kar, V. and Webb, B.}, title = {{In silico design and physicochemical characterisation of a dual-action intranasal nanoparticle formulation for Alzheimer’s disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10822803/v1}, url = {https://doi.org/10.21203/rs.3.rs-10822803/v1} } @article{elsheikh2026-9ea25c4a, author = {El-Sheikh, M. and Al-ruwaili, R. and Al-Maduh, A. and Al-Beladi, S.}, title = {{Synergistic Nano-Architectures: How Date Seed Phytochemicals and Cellulose Matrices Template Silver Nanoparticles for Multifunctional Therapy}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10617300/v1}, url = {https://doi.org/10.21203/rs.3.rs-10617300/v1} } @article{ban2026-0ffeafec, author = {Ban, K. and Kajiwara, S. and Hashizume, T. and Ninomiya, M. and Koketsu, M.}, title = {{Structural optimization of coumarin-pyridine hybrid derivative salts as potent acetylcholinesterase inhibitors}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10583076/v1}, url = {https://doi.org/10.21203/rs.3.rs-10583076/v1} } @article{rautela2026-3e3bf661, author = {Rautela, R. and Gupta, S. M. and Gaurav, A.}, title = {{Discovery of Natural Cholinesterase Inhibitors via Integrated Computational Studies using Labdane-Related Diterpenoids-based Pharmacophore Model and in-vitro studies}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10417596/v1}, url = {https://doi.org/10.21203/rs.3.rs-10417596/v1} } @article{rathi2026-2e030f13, author = {Rathi, R.}, title = {{Computational Screening of FDA-Approved Drugs as Potential BACE1 Inhibitors for Alzheimer's Disease Drug Repurposing}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10465925/v1}, url = {https://doi.org/10.21203/rs.3.rs-10465925/v1} } @article{rahali2026-e54b0b73, author = {Rahali, N. and Soltani, I. and Messaoud, C.}, title = {{Phenolic chemotypic diversity in Tunisian Hertia cheirifolia populations: influence of plant organs and phenological stages on antioxidant and anti-acetylcholinesterase activities}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10140560/v1}, url = {https://doi.org/10.21203/rs.3.rs-10140560/v1} } @article{atmaca2026-4235e404, author = {Atmaca, H. and DÇ, Gürbüz and Erol, M. K. and Yetkin, E.}, title = {{Amantadine, Donepezil and Memantine Associated Arrhythmia in an Elderly Patient}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-9807496/v1}, url = {https://doi.org/10.21203/rs.3.rs-9807496/v1} } @article{paruchuri2026-a6042b4b, author = {Paruchuri, S. and Sivanantharajah, L. and Mudher, A. and Chatterjee, S.}, title = {{Effect of Metformin on tau pathology and proteostasis in cellular and a Drosophila model of Tauopathy}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10786020/v1}, url = {https://doi.org/10.21203/rs.3.rs-10786020/v1} } @article{li2026-314444c7, author = {Li, J. and Li, Y. and Bhat, A. and Zheng, M. and Zhang, Q.}, title = {{Low-dose lithium prevents age-dependent metabolic stress–driven alzheimer’s disease–like pathology through restoration of the NAMPT–NAD⁺–SIRT1–AMPK–TFEB metabolic resilience network}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10738655/v1}, url = {https://doi.org/10.21203/rs.3.rs-10738655/v1} } @article{duche2026-0146b3bc, author = {Duche, A. and Chandnra, D. V. and Han, D. and Sumbria, R. K. and Rahman, M.}, title = {{Hepatic and Brain Spatial Gene Expression Changes in Intragastric Alcohol Fed APP/PS1 Alzheimer's Disease Mouse Model}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10760512/v1}, url = {https://doi.org/10.21203/rs.3.rs-10760512/v1} } @article{baral2026-e2e1ba0c, author = {Baral, D. S. and Verma, R.}, title = {{Exploring the Molecular and Biochemical Mechanisms of Aromasin in Modulating COX-2/iNOS for Alzheimer’s Disease-Associated Synaptic Dysfunction: An In Silico Drug Repurposing Study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10701602/v1}, url = {https://doi.org/10.21203/rs.3.rs-10701602/v1} } @article{tian2026-47e82ed4, author = {Tian, M. and Zhu, X. and Lei, Z. and Lu, Y. and Mo, L. and Tan, J.}, title = {{Taulipro rescues mitochondrial dysfunction and inhibits cGAS–STING neuroinflammation in Aβ-driven Alzheimer's disease models}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10416296/v1}, url = {https://doi.org/10.21203/rs.3.rs-10416296/v1} } @article{takechi2026-25853c66, author = {Takechi, R. and Dunne, J. and Lam, V. and Stephan, B. M. and Pereira, G. and Clarnette, R. and Watts, G. F. and Flicker, L. and others}, title = {{Repurposing probucol for prevention of dementia: a nationwide cohort study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10311061/v1}, url = {https://doi.org/10.21203/rs.3.rs-10311061/v1} } @article{rathi2026-5bb621f8, author = {Rathi, R.}, title = {{Computational Screening of 1,348 FDA-Approved Drugs as Potential BACE1 Inhibitors for Alzheimer's Disease Drug Repurposing}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10484841/v1}, url = {https://doi.org/10.21203/rs.3.rs-10484841/v1} } @article{yildiz2026-01133a22, author = {Yildiz, M. and Winstead, V. and Jacob, A. and Nemariam, A. and Paul, N. and Pickering, C.}, title = {{The Effect of Noncontingent Monetary Incentives in Recruitment Letters on Research Enrollment of Alzheimer’s Disease and Related Dementia Caregiving Dyads: A Study Within a Trial (SWAT) Randomized Controlled Trial}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10818940/v1}, url = {https://doi.org/10.21203/rs.3.rs-10818940/v1} } @article{afifi2026-fb5f31f1, author = {Afifi, T. and Collins, N. and Rand, K. and Stamps, J. and Naffziger, E. and Truscelli, N. and Harris, P. and Neumann, T. and others}, title = {{The effects of virtual reality and video conferencing on personal and relational well-being among older adults with cognitive impairments and their adult children: The Thrive randomized controlled trial}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10584186/v1}, url = {https://doi.org/10.21203/rs.3.rs-10584186/v1} } @article{zhong2026-9d3fb2a4, author = {ZHONG, M.}, title = {{Building Cognitive Lines of Defense: A Life-Course Prevention Strategy for Alzheimer's Disease—An Evidence-Based Multi-Stage Intervention Protocol}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10476642/v1}, url = {https://doi.org/10.21203/rs.3.rs-10476642/v1} } @article{shumaker2026-af6361e3, author = {Shumaker, M. 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J. and Lee, S.}, title = {{Stable and Interpretable Cognitive Status Screening Using Longitudinal Wearable Data}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11111108/v1}, url = {https://doi.org/10.21203/rs.3.rs-11111108/v1} } @article{wojcikpedziwiatr2026-87cd86ca, author = {Wójcik-Pędziwiatr, M. and Tomaszewska, A. and Dębska, G. and Rudzińska-Bar, M.}, title = {{Insomnia symptoms, daytime sleepiness, and quality of life in people with Alzheimer’s disease: a secondary cross-sectional analysis}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10705206/v1}, url = {https://doi.org/10.21203/rs.3.rs-10705206/v1} } @article{vaknalli2026-370e6321, author = {Vaknalli, R. N. and Addo-Osafo, K. and C, V. S. 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T. and others}, title = {{Coronary artery disease and neurocognitive performance among older adults in Uganda}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10737115/v1}, url = {https://doi.org/10.21203/rs.3.rs-10737115/v1} } @article{chi2026-ca10c8ff, author = {Chi, W. and Liou, T. and Wang, W. and Yen, C. and Liao, H. and Huang, W. W.}, title = {{Prognostic heterogeneity within cognitive stages: a nationwide cohort study of everyday functional difficulties and mortality in 202,508 older adults}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11248817/v1}, url = {https://doi.org/10.21203/rs.3.rs-11248817/v1} } @article{zokaee2026-b9b46d6c, author = {Zokaee, M.}, title = {{“The conversation wouldn’t happen without us”: How interpreter involvement affects dementia service delivery for CALD clients in Australia}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10716470/v1}, url = {https://doi.org/10.21203/rs.3.rs-10716470/v1} } @article{timler2026-eec99df9, author = {Timler, W. and Hoang, M. T. and Kempa-Timler, J. and Religa, D. and Kardas, P.}, title = {{The influence of cognitive decline on the severity and quantity of drug-drug interactions}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10957736/v1}, url = {https://doi.org/10.21203/rs.3.rs-10957736/v1} } @article{staller2026-122ddc0e, author = {Staller, J. and Alm, A. K. and Kristiansen, L. P.}, title = {{What Do Care Staff Know About Behavioural and Psychological Symptoms of Dementia? A Mixed- Methods Study in Long-Term Care}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10731138/v1}, url = {https://doi.org/10.21203/rs.3.rs-10731138/v1} } @article{rodrigues2026-7cb394ba, author = {Rodrigues¹, J. O. and Silva, T. L. and LdR, de Souza}, title = {{Brief Communication: Frailty and Neurocognitive Impairment in Older People Living with HIV: A Cross-Sectional Study from Southeastern Brazil}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11107308/v1}, url = {https://doi.org/10.21203/rs.3.rs-11107308/v1} } @article{yan2026-31e6d955, author = {Yan, Q. and Li, M. and Li, N. and Wu, X. and Ni, Y. and Dong, C. and Wang, W. and Yu, H.}, title = {{Caregiving experiences of older-adult informal family caregivers for older adults with comorbid dementia and physical disability: A qualitative study using the caregiving stress-process model}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10729643/v1}, url = {https://doi.org/10.21203/rs.3.rs-10729643/v1} } @article{kim2026-183d1759, author = {Kim, J. and Kwon, E. J. and Ahn, J. H. and Cho, E. A. and Shim, J. and Lee, S. and Park, M. and Oh, E. J.}, title = {{Newly diagnosed postoperative depression and incident dementia after major surgery: a Korean nationwide retrospective cohort study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10811216/v1}, url = {https://doi.org/10.21203/rs.3.rs-10811216/v1} } @article{vaz2026-de3ff1a4, author = {Vaz, E. A. B. and Porcatti, L. R. and Barbosa, G. C. and Silveira, A. C. S. L. and Girotto, R. S. and Caparrol, A. J. S. and Silva, K. I. 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E.}, title = {{Panel-Gene Transcriptomic Associations and Published-Variant Architecture in Parkinson Disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11097203/v1}, url = {https://doi.org/10.21203/rs.3.rs-11097203/v1} } @article{lee2026-e65dac19, author = {Lee, H. and Cho, Y. and Park, S. J. and Kang, J. H. and Chung, J. and Yu, J. and Park, Y. J. and Seo, D. and others}, title = {{Association between urban green space coverage and incident Alzheimer’s disease among older adults in metropolitan South Korea: a population-based retrospective cohort study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10506133/v1}, url = {https://doi.org/10.21203/rs.3.rs-10506133/v1} } @article{wang2026-13e8938d, author = {Wang, F. and Li, P. and Huang, R. S.}, title = {{Constraint Based Metabolic Modeling Identifies Robust Biomarkers and Therapeutic Target Combinations in Alzheimer Disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11324647/v1}, url = {https://doi.org/10.21203/rs.3.rs-11324647/v1} } @article{matthews2026-066e4624, author = {Matthews, D. B. and Staebell, L. and Feller, S. and Kendrick, J. and Hartwig, J. and Riley, A. and II, M. 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S. and Lee, Y. and Oh, C.}, title = {{Human multiscale transcriptomics identifies the NLRP3 inflammasome as a convergent druggable target in Alzheimer’s disease: validation with dimethyl itaconate in 5xFAD mice}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11103693/v1}, url = {https://doi.org/10.21203/rs.3.rs-11103693/v1} } @article{antonova2026-e8cd5270, author = {Antonova, D. and Gurenko, S. and Pegova, M. and Ustinova, A. and Shteynberg, G. and Chukanov, V. and Pchitskaya, E.}, title = {{SpineTool 2.0: A Deep Learning Platform with an Interactive User Interface for Dendritic Spine Segmentation and Morphological Analysis}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10996498/v1}, url = {https://doi.org/10.21203/rs.3.rs-10996498/v1} } @article{huang2026-f63e9b8e, author = {Huang, E. and Lu, R. and Choi, J. and Jahan, N. and Imhof, I. and Collo, S. and Eguiguren, S. and Zhang, J. and others}, title = {{TLR7-mediated autoimmunity targets Robo3 to drive astrogliosis in frontotemporal dementia}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11236688/v1}, url = {https://doi.org/10.21203/rs.3.rs-11236688/v1} } @article{meng2026-02371b89, author = {Meng, W. and Zhang, J. and Zhang, S. and Shi, Y. and Wang, H.}, title = {{Aβ42 oligomers disrupt calcium homeostasis via Piezo1 and induce neurotoxicity in differentiated SH-SY5Y cells}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11212419/v1}, url = {https://doi.org/10.21203/rs.3.rs-11212419/v1} } @article{jimenezsanchez2026-0a11e557, author = {Jimenez-Sanchez, M. and Lobo, P. B. and Yang, F. and Power, C. and Böken, D. and Verlin, L. and Guzman-Hernandez, R. and Cantallops-Jimenez, S. and others}, title = {{An astrocyte-neuron HSPB1 axis preserves lysosomal integrity and protects from tau pathology}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11192311/v1}, url = {https://doi.org/10.21203/rs.3.rs-11192311/v1} } @article{yu2026-37f5ced5, author = {Yu, H. and Yang, H. and Shi, J. and Dong, W. and Wang, Z. and Meng, M. and Wang, L. and others}, title = {{PDE4D inhibition activates cAMP-PKA signaling to preserve mitochondrial homeostasis and prevent neuronal necroptosis in Alzheimer's disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11070692/v1}, url = {https://doi.org/10.21203/rs.3.rs-11070692/v1} } @article{nelumdeniya2026-14f24361, author = {Nelumdeniya, N. and Sabalingham, S. and Karunathilaka, R. and Jayakody, R. S.}, title = {{Neuroprotective Effects and Mechanisms of Cannabinoids in In Vitro Cell Models of Neurodegenerative Diseases: A Scoping Review}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11027426/v1}, url = {https://doi.org/10.21203/rs.3.rs-11027426/v1} } @article{jajin2026-f5a97635, author = {Jajin, E. A. and Zempel, H.}, title = {{Integrative Multiomics Analysis Reveals a Coordinated Molecular Signature of Neuroresilience in human MAPT-knockout hiPSC-derived Neurons with relevance for Alzheimer’s and Neurodegenerative Disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11112521/v1}, url = {https://doi.org/10.21203/rs.3.rs-11112521/v1} } @article{li2026-66649645, author = {Li, H. and Cheng, Y. and Lin, X. and Feng, Y. and Du, B. and Dou, B. and Sheng, Z. and Xu, F. and others}, title = {{PDE2A Modulation Attenuates Aβ-Induced Neuronal Injury and Associated Oxidative, Inflammatory, and Apoptotic Responses}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10975363/v1}, url = {https://doi.org/10.21203/rs.3.rs-10975363/v1} } @article{turnbull2026-ca089d79, author = {Turnbull, N. and Kongmant, R. and Hughes, D. and Toontom, N. and Chanawong, M.}, title = {{Elder Caregiving in Southeast Asia: A Systematic Review of Cultural Norms, Care Burdens, Carer Support and Policy Gaps}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-8671736/v1}, url = {https://doi.org/10.21203/rs.3.rs-8671736/v1} } @article{demnitzking2026-cfd815eb, author = {Demnitz-King, H. and Darby, A. and Davies, N. and McAdams, C. and Owusu-Ansha, A. and Rauf, M. and Phillips, R. and Sims, W. and others}, title = {{Co-adapting the GRACE (Goal-diRected ACcessible, Equitable, Evidence-based Care) Dementia Post-diagnostic Support Intervention to Improve Inclusivity}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10949196/v1}, url = {https://doi.org/10.21203/rs.3.rs-10949196/v1} } @article{cheng2026-9af913f5, author = {CHENG, W. K. W.}, title = {{Separating ECog scale-score information from dyad availability: observation-process contributions to dyadic prediction of cognitive impairment in ADNI}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10884877/v3}, url = {https://doi.org/10.21203/rs.3.rs-10884877/v3} } @article{cheng2026-6910e9a6, author = {CHENG, W. K. W.}, title = {{Dyadic self- and informant-reported cognitive concern and subsequent MCI/AD diagnosis in ADNI: an exploratory prognostic modelling study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10884877/v1}, url = {https://doi.org/10.21203/rs.3.rs-10884877/v1} } @article{onoria2026-9343802e, author = {Onoria, J. L. G. and Mukasa, M. K. and Lwere, K. and Buwembo, D. and Nassanga, R. and Nakasujja, N.}, title = {{The Complex Dynamics of Caregiving for ADRD Patients in Uganda: Selection Factors, Challenges, and Benefits}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10625978/v1}, url = {https://doi.org/10.21203/rs.3.rs-10625978/v1} } @article{huang2026-4bfc7d14, author = {Huang, L. and Ruan, T. and Li, X. and Song, X. and Li, J. and q, Zhao and Teng, L.}, title = {{The mediating effects of attitudes toward people with dementia on the relationship between caregiving burden and sense of competence among dementia care staff in Southern Chinese nursing homes: A cross-sectional study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10491995/v1}, url = {https://doi.org/10.21203/rs.3.rs-10491995/v1} } @article{spk2026-09180344, author = {Spk, mudiyanselage and Liu, Y. and Tseng, H. and Lin, M.}, title = {{Artificial intelligence education for health science and non-STEM students: a mixed- methods evaluation of an interdisciplinary mental health prototype development program}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10109745/v1}, url = {https://doi.org/10.21203/rs.3.rs-10109745/v1} } @article{wong2026-adeac096, author = {Wong, L. and Kwok, C. and KOO, F. K. and Tang, C. and Chenoweth, L.}, title = {{Co-design, Cultural Adaptation, and Mixed-Methods Evaluation of a Carer Support Program for Chinese Australian Dementia Carers}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10491749/v1}, url = {https://doi.org/10.21203/rs.3.rs-10491749/v1} } @article{koo2026-959b7dea, author = {KOO, F. K. and Wong, L. and Chenoweth, L. and Tang, C. and Kwok, C.}, title = {{Building confidence in dementia care: The experience of Chinese Carers in participation in culturally and linguistically appropriate Carer Support Program}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10491834/v1}, url = {https://doi.org/10.21203/rs.3.rs-10491834/v1} } @article{sim2026-0bed91a8, author = {Sim, J. Y. S. and Choong, H. P. B. and Ng, S. L. A. and Tan, Y. Z. N. and Wang, S. and Zhou, W.}, title = {{Navigating young-onset dementia caregiving: A qualitative study of unmet needs, support, and resilience}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10249782/v1}, url = {https://doi.org/10.21203/rs.3.rs-10249782/v1} } @article{hailu2026-98c647e6, author = {Hailu, G. N. and Caroline, W. P. and GdO, Tavares and PAdS, Silva and Tesfay, Z. A. and IVLd, Nascimento and CJdA, Silva and Arantes, S. L. and others}, title = {{Caring in the Shadows: The Lived Experiences of family Caregivers of Older Adults with Dementia in Fragile and Conflict-Affected Setting in Ethiopia}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10317363/v1}, url = {https://doi.org/10.21203/rs.3.rs-10317363/v1} } @article{yokus2026-cd317d80, author = {Yokus, S. 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M. and Tadri, M. and Agüera-Ortiz, L. and Reeves, S. and Stewart, R. and Mueller, C. and others}, title = {{The prognostic significance of distinct psychosis symptom profiles in dementia: A cohort study using linked electronic health records}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10472741/v1}, url = {https://doi.org/10.21203/rs.3.rs-10472741/v1} } @article{medveyuk2026-b46b3dcd, author = {Medveyuk, S. and Vervaecke, D. and Nguyen, H. and Corbett, K. and Dymchuk, E. and Baghini, B. Z. and Slavescu, I. and Tate, K. and others}, title = {{How and why adult day programs influence admissions to long-term care homes for persons living with dementia: A program theory based on a realist review}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-9918025/v1}, url = {https://doi.org/10.21203/rs.3.rs-9918025/v1} } @article{araujo2026-fe421bec, author = {Araujo, S. F. C. and ÂH, Bonfim and MEdA, Silva and Dechen, J. M. and de Almeida, D. N. S. and Sztutman, L. C. and Galvão, P. V. M.}, title = {{Person-Centred Care: Impact on the Effectiveness of Palliative Care in Patients with Alzheimer’s Disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10778779/v1}, url = {https://doi.org/10.21203/rs.3.rs-10778779/v1} } @article{ewing2026-e30eb38b, author = {Ewing, M. 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Y. and Diaz, A. and Gove, D. and Jessen, F. and Khoury, C. P. and Wiley, R. E. and El-Hayek, Y. H.}, title = {{Person-Centredness in Dementia Diagnosis \& Detection: A Scoping Review}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10092382/v1}, url = {https://doi.org/10.21203/rs.3.rs-10092382/v1} } @article{jivan2026-7fa029f3, author = {Jivan, D. and Mestre, T.}, title = {{Connecting the Dots in Parkinson’s care: A Rapid Review and Qualitative Synthesis of Multidisciplinary Patient Passports for Parkinson’s disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-9579242/v1}, url = {https://doi.org/10.21203/rs.3.rs-9579242/v1} } @article{wang2026-7bc8dc76, author = {Wang, Y. and Li, L. and Zhe, L. and Zhang, S. and Jiao, Y. and Li, F.}, title = {{Assessment of potentially inappropriate medications using STOPPFrail V2 criteria and OncPal guideline in elderly cancer patients with end-stage disease: A cross-sectional study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-9733500/v1}, url = {https://doi.org/10.21203/rs.3.rs-9733500/v1} } @article{benouajjit2026-4a203f81, author = {BENOUAJJIT, A. and SOUIRTI, Z.}, title = {{Prevalence of dementia and mild cognitive impairment in Morocco: A population-based study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11054017/v1}, url = {https://doi.org/10.21203/rs.3.rs-11054017/v1} } @article{li2026-5ca980db, author = {Li, L. and Wang, B. and Hao, L. and Wang, S. and Sun, Y. and Cui, J. and Zhang, Y. and Hu, R.}, title = {{Prevalence and influencing factors of cognitive frailty among elderly hypertensive rural community residents of Inner Mongolia, China:A Cross-Sectional Survey}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10422816/v1}, url = {https://doi.org/10.21203/rs.3.rs-10422816/v1} } @article{bharadwaj2026-a7bfc0b6, author = {Bharadwaj, Y.}, title = {{Research Trends of Drama Therapy in Mental Health : A Comprehensive Bibliometric analysis}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10691733/v1}, url = {https://doi.org/10.21203/rs.3.rs-10691733/v1} } @article{hammad2026-0b0753c5, author = {Hammad, G. and Seret, E. and Schmidt, C. and Vandewalle, G.}, title = {{Determinants of fractal motor activity regulation: insights from a large community-dwelling multi-ethnic population}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10237495/v1}, url = {https://doi.org/10.21203/rs.3.rs-10237495/v1} } @article{frerk2026-033fcf76, author = {Frerk, T. and Vogelgesang, F. and Thamm, R. and Julia, T. and Joachim, S. and Schumacher, C. and Marschall, U. and Grobe, T. G.}, title = {{How Much Non-response Matters? Diagnosis Prevalence Estimates in Survey Participants Versus the Total Sample}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10216874/v1}, url = {https://doi.org/10.21203/rs.3.rs-10216874/v1} } @article{sen2026-e890aa4f, author = {Sen, S. E.}, title = {{A Transferable Health Economic Evaluation Framework for Alzheimer’s Disease-Modifying Therapies}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-9602832/v1}, url = {https://doi.org/10.21203/rs.3.rs-9602832/v1} } @article{vicentegarcia2026-ff872dac, author = {Vicente-García, C. and Gállego-Royo, A. and Esteban, E. M. A. and Aguilar-Latorre, A. and Méndez-López, F. and Magallón-Botaya, M. R.}, title = {{The Contribution of Routinely Collected Clinical Data to Dementia Identification in Primary Care: A Cross-Sectional Study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10985825/v1}, url = {https://doi.org/10.21203/rs.3.rs-10985825/v1} } @article{vilella2026-6ddf0c22, author = {Vilella, D. and Tafuri, B. and Urso, D. and Rollo, E. and Giannoni-Luza, S. and Gigli, G. and Tartaglione, B. and Logroscino, G.}, title = {{A Machine Learning-Based Framework for differential screening of Neurodegenerative Dementias using routine clinical data}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10815316/v1}, url = {https://doi.org/10.21203/rs.3.rs-10815316/v1} } @article{ahmadi2026-5d93c013, author = {Ahmadi, F. and Bidabad, B.}, title = {{Hippocampal surface analysis using discrete Ricci flow and Riemannian metrics for the diagnosis of Alzheimer's disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10382441/v1}, url = {https://doi.org/10.21203/rs.3.rs-10382441/v1} } @article{pai2026-8b96bc40, author = {Pai, A. and Huntington-Alfano, K. and Jain, H. and McAlear, C. and Rivet, C. and Forester, B. P.}, title = {{EHR-Enabled Alzheimer’s Disease Care Pathways in Primary Care: Results from a Multisite Implementation Pilot}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10767751/v1}, url = {https://doi.org/10.21203/rs.3.rs-10767751/v1} } @article{lin2026-052693e4, author = {Lin, P. and Huang, L. and Xu, P. and Shi, Y. and Zhu, J. and Zhang, J. and He, M. and Guo, J.}, title = {{Risk factors for Dementia Public Stigma in Zhejiang Province, China: A Cross-Sectional Study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10491650/v1}, url = {https://doi.org/10.21203/rs.3.rs-10491650/v1} } @article{denobile2026-b06ba9dd, author = {de Nobile, A. and Borghi, I. and De Pasquale, P. and Berger, D. J. and Maselli, A. and Lorenzo, F. 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R. and Almutairi, A. S.}, title = {{Knowledge predicts attitudes toward dementia among hospital nurses in Saudi Arabia: a cross-sectional study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10719820/v1}, url = {https://doi.org/10.21203/rs.3.rs-10719820/v1} } @article{li2026-b6ccdbd2, author = {Li, Z. and Liu, M. and Zhao, G. and Cai, Q. and Wan, S.}, title = {{Pain is independently associated with agitation and neuropsychiatric symptoms in Alzheimer’s disease: a cross-sectional MRI study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10907338/v1}, url = {https://doi.org/10.21203/rs.3.rs-10907338/v1} } @article{zaareer2026-bd508402, author = {Za'areer, M. A. and Jafari, A. 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M.}, title = {{Neuroimaging of affective symptoms in Lewy body dementia: A systematic review}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-7472898/v2}, url = {https://doi.org/10.21203/rs.3.rs-7472898/v2} } @article{khadka2026-eab8d261, author = {Khadka, R. and Samjhana}, title = {{Entropy Anatomy of Pre-Agitation Activity Disruption in the TIHM Home-Monitoring Cohort}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10362909/v1}, url = {https://doi.org/10.21203/rs.3.rs-10362909/v1} } @article{shakya2026-d32827ed, author = {Shakya, S. and Khadka, R.}, title = {{Alert Policy and Rare-Event Metrics for Seven-Day-Ahead Agitation Forecasting in Passive Dementia Monitoring}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10328423/v1}, url = {https://doi.org/10.21203/rs.3.rs-10328423/v1} } @article{suganya2026-3d051a9b, author = {Suganya, S. and Prasath, A. R.}, title = {{PaliGemX: An Interpretable Multimodal Transformer for Early Alzheimer’s Detection}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11122884/v1}, url = {https://doi.org/10.21203/rs.3.rs-11122884/v1} } @article{browder2026-cfe28573, author = {Browder, S. E. and Laivuori, M. and McIntee, T. and Leese, P. J. and Alabi, O. and McGinigle, K. L.}, title = {{Electronic Health Record-Based Machine Learning Models for Predicting Revascularization, Amputation, and Cardiovascular Mortality in At-Risk Patients}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10977718/v1}, url = {https://doi.org/10.21203/rs.3.rs-10977718/v1} } @article{tao2026-eaf460ca, author = {Tao, J. and Caggiano, C. C.}, title = {{Artificial Intelligence for Alzheimer’s Disease Detection Across Neuroimaging and Speech: A Reproducible Cross-Modal Secondary Analysis}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11106125/v1}, url = {https://doi.org/10.21203/rs.3.rs-11106125/v1} } @article{arafat2026-cd543ea2, author = {Arafat, F.}, title = {{A Multimodal Mathematical and Computational Framework for Personalized Medication-Adherence and Cognitive-Risk Modeling in Alzheimer's Disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11042021/v1}, url = {https://doi.org/10.21203/rs.3.rs-11042021/v1} } @article{solepadulles2026-9d60841a, author = {Solé-Padullés, C. and Perera-Cruz, O. and Güell-Brugués, A. and Cabello-Toscano, M. and Mulet-Pons, L. and Morse, R. M. and Cattaneo, G. and Solana-Sánchez, J. and others}, title = {{Repetitive negative thinking moderates the association between self-referential thoughts and cognition amongst older adults: a natural speech analysis approach}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10775960/v1}, url = {https://doi.org/10.21203/rs.3.rs-10775960/v1} } @article{chiarella2026-eb5bfb2c, author = {Chiarella, L. S. and Acar, L. and Dahmann, S. and Jin, L. and Otto, T. and Marschall, U. and Nzomo, M. M. and Hirsch, T. and others}, title = {{Reduced Dementia Incidence Following Neck Dissection: A Population-based Matched Cohort Study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10718409/v1}, url = {https://doi.org/10.21203/rs.3.rs-10718409/v1} } @article{salah2026-0e313e69, author = {Salah, R.}, title = {{Speaker-Wise Dementia Screening fromNaturalistic Speech with Lexical Entropy, Semantic Drift, and Multimodal Fusion}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-9795204/v1}, url = {https://doi.org/10.21203/rs.3.rs-9795204/v1} } @article{ham2026-976d25d7, author = {Ham, H. and Han, A. L. and Bae, M. and Lee, H. and Son, J. and Yeo, J. and Yoon, E. 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L. and Huh, D. and Schulmann, A. and others}, title = {{Selective vulnerability and resilience of thalamic neuronal populations in Frontotemporal Dementia}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10670822/v1}, url = {https://doi.org/10.21203/rs.3.rs-10670822/v1} } @article{leitner2026-e4a188be, author = {Leitner, D. and Kanshin, E. and Balcomb, K. and Askenazi, M. and Suazo, J. and Marta-Ariza, M. and schneider, J. and Ueberheide, B. and others}, title = {{The Amyloid Plaque Proteomes of Alzheimer’s Disease and Mild Cognitive Impairment}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-9012095/v1}, url = {https://doi.org/10.21203/rs.3.rs-9012095/v1} } @article{rafii2025-763c19f0, author = {Rafii, M. and Langford, O. and Schlachetzki, Z. and Zammit, M. and Donohue, M. and Zhou, X. and Sukreet, S. and Abdel-Latif, S. and others}, title = {{Automated Plasma Phospho-tau217 Assays for the diagnosis of Down Syndrome-Related Alzheimer's Disease}}, journal = {Research Square}, year = {2025}, doi = {10.21203/rs.3.rs-7359108/v1}, url = {https://doi.org/10.21203/rs.3.rs-7359108/v1} } @article{zhang2026-2356de84, author = {Zhang, N. and Liu, M. and Gu, J.}, title = {{Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11366061/v1}, url = {https://doi.org/10.21203/rs.3.rs-11366061/v1} } @article{trivedi2026-9a7ee369, author = {Trivedi, M. and Chirravuri, R. and Schwedt, T. J. and Ischii, R. and Dumkrieger, G. and Dodick, D. and Gottschalk, C. H. and Tepper, S. J. and others}, title = {{Cognitive Impairment during Migraine Attacks: An Analysis from the American Registry for Migraine Research (ARMR)}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11118845/v1}, url = {https://doi.org/10.21203/rs.3.rs-11118845/v1} } @article{churchill2026-ace85e9d, author = {Churchill, L. and Konuri, A. and Anderson, J. and Ignatavicius, A. and Lewis, S. J. and Matar, E.}, title = {{Limbic Vulnerability Characterises REM Sleep Behaviour Disorder Across Prodromal and Established Lewy Body Disease}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11109305/v1}, url = {https://doi.org/10.21203/rs.3.rs-11109305/v1} } @article{huang2026-e8078740, author = {Huang, H. and Chen, L. and Chen, J. and Hyun, J. and Loftus, J. and Melmed, K. and Orringer, D. and Frontera, J. and others}, title = {{Neuro-JEPA: Building and Evaluating Health-System Scale Neuroimaging Foundation Models with Mixture of Experts}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11130462/v1}, url = {https://doi.org/10.21203/rs.3.rs-11130462/v1} } @article{maurice2026-99d51892, author = {Maurice, O. R. and Jones, C. and Pliatsikas, C. and Sheehan, A. and Harris, C. B.}, title = {{Multilingualism and ageing: Cognitive and affective trajectories in the Australian Longitudinal Study of Ageing}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11186040/v1}, url = {https://doi.org/10.21203/rs.3.rs-11186040/v1} } @article{farzana2026-758053b6, author = {Farzana, S. and Arian, A. and Desvarieux3, Moïse and Rundek, Tatjana Rundek4 and Ahsan, H.}, title = {{Evaluating Patient Representation Strategies for Early Prediction of Alzheimer’s Disease and Related Dementias from Longitudinal EHRs}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10988118/v1}, url = {https://doi.org/10.21203/rs.3.rs-10988118/v1} } @article{luo2026-bb061755, author = {Luo, H. and Zhang, G. and Long, L. and Chen, W. and Liu, Y.}, title = {{Exercise effects on balance confidence and concerns about falling in older adults with cognitive impairment: a construct-stratified meta-analysis}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10741058/v1}, url = {https://doi.org/10.21203/rs.3.rs-10741058/v1} } @article{neufang2026-b007979c, author = {Neufang, S. and Akhrif, A. and Beyan, O. 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F. and {Initiative ADN}}, title = {{A Pipeline for ADNI Resting-State Functional MRI Processing and Quality Control}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-11132707/v1}, url = {https://doi.org/10.21203/rs.3.rs-11132707/v1} } @article{kim2026-be334a05, author = {Kim, H. and Zang, C. and Lee, J. and Haddad, E. and Park, G. and Zhang, J. and Kim, J. and Choi, K. and others}, title = {{Tissue- and compartment-resolved brain age reveals vascular-metabolic and neurodegenerative aging}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10808325/v1}, url = {https://doi.org/10.21203/rs.3.rs-10808325/v1} } @article{mourya2026-e7a2d6b7, author = {Mourya, S. K. and Yadav, A. K. 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