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% Source: https://alzhub.org/research?journal=Nature+Medicine
% 124 entries, in the order the page lists them. Built from alzhub.org's own records.
% 0 entries have no readable author in the source record and carry no author field.

@article{brodaty2025-39875685,
  author  = {Brodaty, Henry and Chau, Tiffany and Heffernan, Megan and Ginige, Jeewani A and Andrews, Gavin and Millard, Michael and Sachdev, Perminder S and Anstey, Kaarin J and others},
  title   = {{An online multidomain lifestyle intervention to prevent cognitive decline in at-risk older adults: a randomized controlled trial}},
  journal = {Nature medicine},
  year    = {2025},
  doi     = {10.1038/s41591-024-03351-6},
  pmid    = {39875685},
  url     = {https://doi.org/10.1038/s41591-024-03351-6}
}

@article{fang2025-39806070,
  author  = {Fang, M. and Hu, J. and Weiss, J. and Knopman, D. S. and Albert, M. and Windham, B. G. and Walker, K. A. and Sharrett, A. R. and Gottesman, R. F. and Lutsey, P. L. and others},
  title   = {{Lifetime risk and projected burden of dementia}},
  journal = {Nature Medicine},
  year    = {2025},
  doi     = {10.1038/s41591-024-03340-9},
  pmid    = {39806070},
  url     = {https://doi.org/10.1038/s41591-024-03340-9}
}

@article{salloway2021-34155411,
  author  = {Salloway, S. and Farlow, M. and McDade, E. and Clifford, D. B. and Wang, G. and Llibre-Guerra, J. J. and Hitchcock, J. M. and Mills, S. L. and others},
  title   = {{A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease}},
  journal = {Nature medicine},
  year    = {2021},
  doi     = {10.1038/s41591-021-01369-8},
  pmid    = {34155411},
  url     = {https://doi.org/10.1038/s41591-021-01369-8}
}

@article{he2025-40258956,
  author  = {He, J. and Zhao, C. and Zhong, S. and Ouyang, N. and Sun, G. and Qiao, L. and others},
  title   = {{Blood pressure reduction and all-cause dementia in people with uncontrolled hypertension: an open-label, blinded-endpoint, cluster-randomized trial}},
  journal = {Nature Medicine},
  year    = {2025},
  doi     = {10.1038/s41591-025-03616-8},
  pmid    = {40258956},
  url     = {https://doi.org/10.1038/s41591-025-03616-8}
}

@article{bellaver2023-37248300,
  author  = {Bellaver, B. and Povala, G. and Ferreira, P. C. L. and Ferrari-Souza, J. P. and Leffa, D. T. and Lussier, F. Z. and Benedet, A. L. and Ashton, N. J. and Triana-Baltzer, G. and Kolb, H. C. and Tissot, C. and Therriault, J. and others},
  title   = {{Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer's disease}},
  journal = {Nature Medicine},
  year    = {2023},
  doi     = {10.1038/s41591-023-02380-x},
  pmid    = {37248300},
  url     = {https://doi.org/10.1038/s41591-023-02380-x}
}

@article{bouzid2023-37322115,
  author  = {Bouzid, H. and Belk, J. A. and Jan, M. and Qi, Y. and Sarnowski, C. and Wirth, S. and Ma, L. and Chrostek, M. R. and others},
  title   = {{Clonal hematopoiesis is associated with protection from Alzheimer's disease}},
  journal = {Nature medicine},
  year    = {2023},
  doi     = {10.1038/s41591-023-02397-2},
  pmid    = {37322115},
  url     = {https://doi.org/10.1038/s41591-023-02397-2}
}

@article{edison2025-41326666,
  author  = {Edison, P. and Femminella, G. D. and Ritchie, C. and Nowell, J. and Holmes, C. and Walker, Z. and Ridha, B. and Raza, S. and Livingston, N. R. and Frangou, E. and others},
  title   = {{Liraglutide in mild to moderate Alzheimer's disease: a phase 2b clinical trial}},
  journal = {Nature Medicine},
  year    = {2025},
  doi     = {10.1038/s41591-025-04106-7},
  pmid    = {41326666},
  url     = {https://doi.org/10.1038/s41591-025-04106-7}
}

@article{oh2025-40164724,
  author  = {Oh, H. S. and Urey, D. Y. and Karlsson, L. and Zhu, Z. and Shen, Y. and Farinas, A. and Timsina, J. and Duggan, M. R. and others},
  title   = {{A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer's disease}},
  journal = {Nature medicine},
  year    = {2025},
  doi     = {10.1038/s41591-025-03565-2},
  pmid    = {40164724},
  url     = {https://doi.org/10.1038/s41591-025-03565-2}
}

@article{pascoal2021-34446931,
  author  = {Pascoal, T. A. and Benedet, A. L. and Ashton, N. J. and Kang, M. S. and Therriault, J. and Chamoun, M. and Savard, M. and Lussier, F. Z. and others},
  title   = {{Microglial activation and tau propagate jointly across Braak stages}},
  journal = {Nature medicine},
  year    = {2021},
  doi     = {10.1038/s41591-021-01456-w},
  pmid    = {34446931},
  url     = {https://doi.org/10.1038/s41591-021-01456-w}
}

@article{shanks2024-38760589,
  author  = {Shanks, H. R. C. and Chen, K. and Reiman, E. M. and Blennow, K. and Cummings, J. L. and Massa, S. M. and Longo, F. M. and Börjesson-Hanson, A. and others},
  title   = {{p75 neurotrophin receptor modulation in mild to moderate Alzheimer disease: a randomized, placebo-controlled phase 2a trial}},
  journal = {Nature medicine},
  year    = {2024},
  doi     = {10.1038/s41591-024-02977-w},
  pmid    = {38760589},
  url     = {https://doi.org/10.1038/s41591-024-02977-w}
}

@article{ossenkoppele2022-36357681,
  author  = {Ossenkoppele, R. and Pichet Binette, A. and Groot, C. and Smith, R. and Strandberg, O. and Palmqvist, S. and Stomrud, E. and Tideman, P. and others},
  title   = {{Amyloid and tau PET-positive cognitively unimpaired individuals are at high risk for future cognitive decline}},
  journal = {Nature medicine},
  year    = {2022},
  doi     = {10.1038/s41591-022-02049-x},
  pmid    = {36357681},
  url     = {https://doi.org/10.1038/s41591-022-02049-x}
}

@article{janelidze2020-32123385,
  author  = {Janelidze, S. and Mattsson, N. and Palmqvist, S. and Smith, R. and Beach, T. G. and Serrano, G. E. and Chai, X. and Proctor, N. K. and others},
  title   = {{Plasma P-tau181 in Alzheimer's disease: relationship to other biomarkers, differential diagnosis, neuropathology and longitudinal progression to Alzheimer's dementia}},
  journal = {Nature medicine},
  year    = {2020},
  doi     = {10.1038/s41591-020-0755-1},
  pmid    = {32123385},
  url     = {https://doi.org/10.1038/s41591-020-0755-1}
}

@article{rajji2025-40133524,
  author  = {Rajji, T. K. and Baksh, S. N. and Shade, D. M. and Ismail, Z. and Burhan, A. M. and Okhravi, H. R. and Padala, P. R. and Rosenberg, P. B. and Schneider, L. S. and Porsteinsson, A. P. and others},
  title   = {{Escitalopram for agitation in Alzheimer's dementia: a randomized controlled phase 3 trial}},
  journal = {Nature Medicine},
  year    = {2025},
  doi     = {10.1038/s41591-025-03569-y},
  pmid    = {40133524},
  url     = {https://doi.org/10.1038/s41591-025-03569-y}
}

@article{preische2019-30664784,
  author  = {Preische, O. and Schultz, S. A. and Apel, A. and Kuhle, J. and Kaeser, S. A. and Barro, C. and Gräber, S. and others},
  title   = {{Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer's disease}},
  journal = {Nature medicine},
  year    = {2019},
  doi     = {10.1038/s41591-018-0304-3},
  pmid    = {30664784},
  url     = {https://doi.org/10.1038/s41591-018-0304-3}
}

@article{barthelemy2024-38382645,
  author  = {Barthélemy, N. R. and Salvadó, G. and Schindler, S. E. and He, Y. and Janelidze, S. and Collij, L. E. and Saef, B. and Henson, R. L. and others},
  title   = {{Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests}},
  journal = {Nature medicine},
  year    = {2024},
  doi     = {10.1038/s41591-024-02869-z},
  pmid    = {38382645},
  url     = {https://doi.org/10.1038/s41591-024-02869-z}
}

@article{mummery2026-41787076,
  author  = {Mummery, C. J. and Mayorga, A. J. and Simmons, A. and Chow, T. W. and Burgess, B. and Nguyen, T. and Gao, J. and Budda, B. and Park, L. Q. and Gupta, R. and Li, C. and Shi, L. and others},
  title   = {{The TREM2 agonistic antibody AL002 in early Alzheimer's disease: a phase 2 randomized trial}},
  journal = {Nature Medicine},
  year    = {2026},
  doi     = {10.1038/s41591-026-04273-1},
  pmid    = {41787076},
  url     = {https://doi.org/10.1038/s41591-026-04273-1}
}

@article{temba2025-40181181,
  author  = {Temba, Godfrey S. and Pecht, Tal and Kullaya, Vesla I. and Vadaq, Nadira and Mosha, Mary and Ulas, Thomas and Kanungo, Sneha and van Emst, Liesbeth and others},
  title   = {{Immune and metabolic effects of African heritage diets versus Western diets in men: a randomized controlled trial}},
  journal = {Nature Medicine},
  year    = {2025},
  doi     = {10.1038/s41591-025-03602-0},
  pmid    = {40181181},
  url     = {https://doi.org/10.1038/s41591-025-03602-0}
}

@article{mummery2023-37095250,
  author  = {Mummery, C. J. and Börjesson-Hanson, A. and Blackburn, D. J. and Vijverberg, E. G. B. and De Deyn, P. P. and Ducharme, S. and Jonsson, M. and Schneider, A. and Rinne, J. O. and Ludolph, A. C. and Bodenschatz, R. and Kordasiewicz, H. and others},
  title   = {{Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer's disease: a phase 1b, randomized, placebo-controlled trial}},
  journal = {Nature Medicine},
  year    = {2023},
  doi     = {10.1038/s41591-023-02326-3},
  pmid    = {37095250},
  url     = {https://doi.org/10.1038/s41591-023-02326-3}
}

@article{xue2024-38965435,
  author  = {Xue, C. and Kowshik, S. S. and Lteif, D. and Puducheri, S. and Jasodanand, V. H. and Zhou, O. T. and Walia, A. S. and Guney, O. B. and others},
  title   = {{AI-based differential diagnosis of dementia etiologies on multimodal data}},
  journal = {Nature medicine},
  year    = {2024},
  doi     = {10.1038/s41591-024-03118-z},
  pmid    = {38965435},
  url     = {https://doi.org/10.1038/s41591-024-03118-z}
}

@article{palmqvist2021-34031605,
  author  = {Palmqvist, S. and Tideman, P. and Cullen, N. and Zetterberg, H. and Blennow, K. and {Alzheimer’s Disease Neuroimaging Initiative} and Dage, J. L. and Stomrud, E. and others},
  title   = {{Prediction of future Alzheimer's disease dementia using plasma phospho-tau combined with other accessible measures}},
  journal = {Nature medicine},
  year    = {2021},
  doi     = {10.1038/s41591-021-01348-z},
  pmid    = {34031605},
  url     = {https://doi.org/10.1038/s41591-021-01348-z}
}

@article{sevigny2024-38745011,
  author  = {Sevigny, J. and Uspenskaya, O. and Heckman, L. D. and Wong, L. C. and Hatch, D. A. and Tewari, A. and Vandenberghe, R. and Irwin, D. J. and others},
  title   = {{Progranulin AAV gene therapy for frontotemporal dementia: translational studies and phase 1/2 trial interim results}},
  journal = {Nature medicine},
  year    = {2024},
  doi     = {10.1038/s41591-024-02973-0},
  pmid    = {38745011},
  url     = {https://doi.org/10.1038/s41591-024-02973-0}
}

@article{vogel2021-33927414,
  author  = {Vogel, J. W. and Young, A. L. and Oxtoby, N. P. and Smith, R. and Ossenkoppele, R. and Strandberg, O. T. and La Joie, R. and Aksman, L. M. and others},
  title   = {{Four distinct trajectories of tau deposition identified in Alzheimer's disease}},
  journal = {Nature medicine},
  year    = {2021},
  doi     = {10.1038/s41591-021-01309-6},
  pmid    = {33927414},
  url     = {https://doi.org/10.1038/s41591-021-01309-6}
}

@article{petersen2026-41714746,
  author  = {Petersen, Kellen K and Milà-Alomà, Marta and Li, Yan and Du, Lianlian and Xiong, Chengjie and Tosun, Duygu and Saef, Benjamin and Saad, Ziad S and others},
  title   = {{Predicting onset of symptomatic Alzheimer's disease with plasma p-tau217 clocks}},
  journal = {Nature medicine},
  year    = {2026},
  doi     = {10.1038/s41591-026-04206-y},
  pmid    = {41714746},
  url     = {https://doi.org/10.1038/s41591-026-04206-y}
}

@article{buergel2022-36138150,
  author  = {Buergel, T. and Steinfeldt, J. and Ruyoga, G. and Pietzner, M. and Bizzarri, D. and Vojinovic, D. and Upmeier Zu Belzen, J. and Loock, L. and others},
  title   = {{Metabolomic profiles predict individual multidisease outcomes}},
  journal = {Nature medicine},
  year    = {2022},
  doi     = {10.1038/s41591-022-01980-3},
  pmid    = {36138150},
  url     = {https://doi.org/10.1038/s41591-022-01980-3}
}

@article{moguilner2024-39187698,
  author  = {Moguilner, S. and Baez, S. and Hernandez, H. and Migeot, J. and Legaz, A. and Gonzalez-Gomez, R. and Farina, F. R. and Prado, P. and others},
  title   = {{Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations}},
  journal = {Nature medicine},
  year    = {2024},
  doi     = {10.1038/s41591-024-03209-x},
  pmid    = {39187698},
  url     = {https://doi.org/10.1038/s41591-024-03209-x}
}

@article{fortea2024-38710950,
  author  = {Fortea, J. and Pegueroles, J. and Alcolea, D. and Belbin, O. and Dols-Icardo, O. and Vaqué-Alcázar, L. and Videla, L. and Gispert, J. D. and others},
  title   = {{APOE4 homozygozity represents a distinct genetic form of Alzheimer's disease}},
  journal = {Nature medicine},
  year    = {2024},
  doi     = {10.1038/s41591-024-02931-w},
  pmid    = {38710950},
  url     = {https://doi.org/10.1038/s41591-024-02931-w}
}

@article{dicken2025-40760353,
  author  = {Dicken, Samuel James and Jassil, Friedrich C. and Brown, Adrian Carl and Kalis, Monika and Stanley, Chloe and Ranson, Chaniqua and Ruwona, Tapiwa and Qamar, Sulmaaz and others},
  title   = {{Ultraprocessed or minimally processed diets following healthy dietary guidelines on weight and cardiometabolic health: a randomized, crossover trial}},
  journal = {Nature Medicine},
  year    = {2025},
  doi     = {10.1038/s41591-025-03842-0},
  pmid    = {40760353},
  url     = {https://doi.org/10.1038/s41591-025-03842-0}
}

@article{palmqvist2025-407e7d7f,
  author  = {Palmqvist, Sebastian and Warmenhoven, Noëlle and Anastasi, Federica and Pilotto, Andrea},
  title   = {{Plasma phospho-tau217 for Alzheimer's disease diagnosis in primary and secondary care using a fully automated platform}},
  journal = {Nature Medicine},
  year    = {2025},
  doi     = {10.1038/s41591-025-03622-w},
  pmid    = {40205199},
  url     = {https://doi.org/10.1038/s41591-025-03622-w}
}

@article{phillips2026-42387213,
  author  = {Phillips, Bridget and Sanford, Jessie and Janve, Vaibhav A and Liu, Menghan and Johnson, Matt and Gong, Katherine and Bergmann, Kristy and Lowery, Joseph and others},
  title   = {{Blood-based circular RNAs for early diagnosis of Alzheimer's disease}},
  journal = {Nature medicine},
  year    = {2026},
  doi     = {10.1038/s41591-026-04485-5},
  pmid    = {42387213},
  url     = {https://doi.org/10.1038/s41591-026-04485-5}
}

@article{horie2023-37443334,
  author  = {Horie, K. and Salvadó, G. and Barthélemy, N. R. and Janelidze, S. and Li, Y. and He, Y. and Saef, B. and Chen, C. D. and others},
  title   = {{CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer's disease}},
  journal = {Nature medicine},
  year    = {2023},
  doi     = {10.1038/s41591-023-02443-z},
  pmid    = {37443334},
  url     = {https://doi.org/10.1038/s41591-023-02443-z}
}

@article{horie2025-40164726,
  author  = {Horie, Kanta and Salvadó, Gemma and Koppisetti, Rama K. and Janelidze, Shorena and Barthélemy, Nicolas R. and He, Yingxin and Sato, Chihiro and Gordon, Brian Andrew and others},
  title   = {{Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease}},
  journal = {Nature Medicine},
  year    = {2025},
  doi     = {10.1038/s41591-025-03617-7},
  pmid    = {40164726},
  url     = {https://doi.org/10.1038/s41591-025-03617-7}
}

@article{preische2019-9106bc9f,
  author  = {Preische, O. and Schultz, S. A. and Apel, A. and Kuhle, J. and Kaeser, S. A. and Barro, C. and {Dominantly Inherited Alzheimer Network} and others},
  title   = {{Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer's disease}},
  journal = {Nature Medicine},
  year    = {2019},
  pmid    = {30664784}
}

@article{zhou2020-31932797,
  author  = {Zhou, Y. and Song, W. M. and Andhey, P. S. and Swain, A. and Levy, T. and Miller, K. R. and Poliani, P. L. and Cominelli, M. and others},
  title   = {{Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease}},
  journal = {Nature medicine},
  year    = {2020},
  doi     = {10.1038/s41591-019-0695-9},
  pmid    = {31932797},
  url     = {https://doi.org/10.1038/s41591-019-0695-9}
}

@article{argentieri2025-39972219,
  author  = {Argentieri, M. A. and Amin, N. and Nevado-Holgado, A. J. and Sproviero, W. and Collister, J. A. and Keestra, S. M. and Kuilman, M. M. and Ginos, B. N. R. and others},
  title   = {{Integrating the environmental and genetic architectures of aging and mortality}},
  journal = {Nature medicine},
  year    = {2025},
  doi     = {10.1038/s41591-024-03483-9},
  pmid    = {39972219},
  url     = {https://doi.org/10.1038/s41591-024-03483-9}
}

@article{vanolst2025-40050704,
  author  = {van Olst, L. and Simonton, B. and Edwards, A. J. and Forsyth, A. V. and Boles, J. and Jamshidi, P. and Watson, T. and Shepard, N. and Krainc, T. and Argue, B. M. and Zhang, Z. and Kuruvilla, J. and others},
  title   = {{Microglial mechanisms drive amyloid-β clearance in immunized patients with Alzheimer's disease}},
  journal = {Nature Medicine},
  year    = {2025},
  doi     = {10.1038/s41591-025-03574-1},
  pmid    = {40050704},
  url     = {https://doi.org/10.1038/s41591-025-03574-1}
}

@article{self2023-37667136,
  author  = {Self, W. K. and Holtzman, D. M.},
  title   = {{Emerging diagnostics and therapeutics for Alzheimer disease}},
  journal = {Nature medicine},
  year    = {2023},
  doi     = {10.1038/s41591-023-02505-2},
  pmid    = {37667136},
  url     = {https://doi.org/10.1038/s41591-023-02505-2}
}

@article{duff2025-39885359,
  author  = {Duff, E. P. and Zetterberg, H. and Heslegrave, A. and Dehghan, A. and Elliott, P. and Allen, N. and Runz, H. and Laban, R. and others},
  title   = {{Plasma proteomic evidence for increased β-amyloid pathology after SARS-CoV-2 infection}},
  journal = {Nature medicine},
  year    = {2025},
  doi     = {10.1038/s41591-024-03426-4},
  pmid    = {39885359},
  url     = {https://doi.org/10.1038/s41591-024-03426-4}
}

@article{grande2025-40140622,
  author  = {Grande, Giulia and Valletta, Martina and Rizzuto, Debora and Xia, Xin Rui and Qiu, Chengxuan and Orsini, Nicola and Dale, Matilda and Andersson, Sarah Wamala and others},
  title   = {{Blood-based biomarkers of Alzheimer’s disease and incident dementia in the community}},
  journal = {Nature Medicine},
  year    = {2025},
  doi     = {10.1038/s41591-025-03605-x},
  pmid    = {40140622},
  url     = {https://doi.org/10.1038/s41591-025-03605-x}
}

@article{nihart2025-39901044,
  author  = {Nihart, A. J. and Garcia, M. A. and El Hayek, E. and Liu, R. and Olewine, M. and Kingston, J. D. and Castillo, E. F. and Gullapalli, R. R. and others},
  title   = {{Bioaccumulation of microplastics in decedent human brains}},
  journal = {Nature medicine},
  year    = {2025},
  doi     = {10.1038/s41591-024-03453-1},
  pmid    = {39901044},
  url     = {https://doi.org/10.1038/s41591-024-03453-1}
}

@article{thijssen2020-32123386,
  author  = {Thijssen, E. H. and La Joie, R. and Wolf, A. and Strom, A. and Wang, P. and Iaccarino, L. and Bourakova, V. and Cobigo, Y. and others},
  title   = {{Diagnostic value of plasma phosphorylated tau181 in Alzheimer's disease and frontotemporal lobar degeneration}},
  journal = {Nature medicine},
  year    = {2020},
  doi     = {10.1038/s41591-020-0762-2},
  pmid    = {32123386},
  url     = {https://doi.org/10.1038/s41591-020-0762-2}
}

@article{thapa2026-41495409,
  author  = {Thapa, Rahul and Kjær, Magnus Ruud and He, Bryan D. and Covert, Ian and Moore, Hyatt E. and Hanif, Umaer and Ganjoo, Gauri and Westover, Michael Brandon and others},
  title   = {{A multimodal sleep foundation model for disease prediction}},
  journal = {Nature Medicine},
  year    = {2026},
  doi     = {10.1038/s41591-025-04133-4},
  pmid    = {41495409},
  url     = {https://doi.org/10.1038/s41591-025-04133-4}
}

@article{ashton2022-36456833,
  author  = {Ashton, Nicholas James and Janelidze, Shorena and Mattsson, Niklas and Binette, Alexa Pichet and Strandberg, Olof T. and Brum, Wagner Scheeren and Karikari, Thomas K. and González‐Ortiz, Fernando and Di Molfetta, Guglielmo and Meda, Francisco J. and Jonaitis, Erin McMullen and Koscik, Rebecca L. and Cody, Karly Alex and Betthauser, Tobey J. and Li, Yan and Vanmechelen, Eugeen and Palmqvist, Sebastian and Stomrud, Erik and Bateman, Randall John and Zetterberg, Henrik and Johnson, Sterling C. and Blennow, Kaj and Hansson, Oskar},
  title   = {{Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer’s trial selection and disease monitoring}},
  journal = {Nature Medicine},
  year    = {2022},
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