% alzhub.org library filter % Source: https://alzhub.org/research?journal=JAMA % 202 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{hughes2020-32427305, author = {Hughes, D. and Judge, C. and Murphy, R. and Loughlin, E. and Costello, M. and Whiteley, W. and others}, title = {{Association of Blood Pressure Lowering With Incident Dementia or Cognitive Impairment: A Systematic Review and Meta-analysis}}, journal = {JAMA}, year = {2020}, doi = {10.1001/jama.2020.4249}, pmid = {32427305}, url = {https://doi.org/10.1001/jama.2020.4249} } @article{courtright2024-38227032, author = {Courtright, K. R. and Madden, V. and Bayes, B. and Chowdhury, M. and Whitman, C. and Small, D. S. and Harhay, M. O. and Parra, S. and others}, title = {{Default Palliative Care Consultation for Seriously Ill Hospitalized Patients: A Pragmatic Cluster Randomized Trial}}, journal = {JAMA}, year = {2024}, doi = {10.1001/jama.2023.25092}, pmid = {38227032}, url = {https://doi.org/10.1001/jama.2023.25092} } @article{jansen2015-25988462, author = {Jansen, W. J. and Ossenkoppele, R. and Knol, D. L. and Tijms, B. M. and Scheltens, P. and Verhey, F. R. and Visser, P. J. and {Amyloid Biomarker Study Group} and others}, title = {{Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis}}, journal = {JAMA}, year = {2015}, doi = {10.1001/jama.2015.4668}, pmid = {25988462}, url = {https://doi.org/10.1001/jama.2015.4668} } @article{lenze2022-36511926, author = {Lenze, E. J. and Voegtle, M. and Miller, J. P. and Ances, B. M. and Balota, D. A. and Barch, D. and Depp, C. A. and Diniz, B. S. and others}, title = {{Effects of Mindfulness Training and Exercise on Cognitive Function in Older Adults: A Randomized Clinical Trial}}, journal = {JAMA}, year = {2022}, doi = {10.1001/jama.2022.21680}, pmid = {36511926}, url = {https://doi.org/10.1001/jama.2022.21680} } @article{ossenkoppele2015-25988463, author = {Ossenkoppele, R. and Jansen, W. J. and Rabinovici, G. D. and Knol, D. L. and van der Flier, W. M. and van Berckel, B. N. and Scheltens, P. and Visser, P. J. and others}, title = {{Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis}}, journal = {JAMA}, year = {2015}, doi = {10.1001/jama.2015.4669}, pmid = {25988463}, url = {https://doi.org/10.1001/jama.2015.4669} } @article{schneider2005-16234500, author = {Schneider, L. S. and Dagerman, K. S. and Insel, P.}, title = {{Risk of death with atypical antipsychotic drug treatment for dementia: meta-analysis of randomized placebo-controlled trials}}, journal = {JAMA}, year = {2005}, doi = {10.1001/jama.294.15.1934}, pmid = {16234500}, url = {https://doi.org/10.1001/jama.294.15.1934} } @article{dekosky2008-19017911, author = {DeKosky, S. T. and Williamson, J. D. and Fitzpatrick, A. L. and Kronmal, R. A. and Ives, D. G. and Saxton, J. A. and Lopez, O. L. and Burke, G. and others}, title = {{Ginkgo biloba for prevention of dementia: a randomized controlled trial}}, journal = {JAMA}, year = {2008}, doi = {10.1001/jama.2008.683}, pmid = {19017911}, url = {https://doi.org/10.1001/jama.2008.683} } @article{porsteinsson2014-24549548, author = {Porsteinsson, A. P. and Drye, L. T. and Pollock, B. G. and Devanand, D. P. and Frangakis, C. and Ismail, Z. and Marano, C. and Meinert, C. L. and others}, title = {{Effect of citalopram on agitation in Alzheimer disease: the CitAD randomized clinical trial}}, journal = {JAMA}, year = {2014}, doi = {10.1001/jama.2014.93}, pmid = {24549548}, url = {https://doi.org/10.1001/jama.2014.93} } @article{sink2015-26305648, author = {Sink, K. M. and Espeland, M. A. and Castro, C. M. and Church, T. and Cohen, R. and Dodson, J. A. and Guralnik, J. and Hendrie, H. C. and others}, title = {{Effect of a 24-Month Physical Activity Intervention vs Health Education on Cognitive Outcomes in Sedentary Older Adults: The LIFE Randomized Trial}}, journal = {JAMA}, year = {2015}, doi = {10.1001/jama.2015.9617}, pmid = {26305648}, url = {https://doi.org/10.1001/jama.2015.9617} } @article{witlox2010-20664045, author = {Witlox, J. and Eurelings, L. S. and de Jonghe, J. F. and Kalisvaart, K. J. and Eikelenboom, P. and van Gool, W. A.}, title = {{Delirium in elderly patients and the risk of postdischarge mortality, institutionalization, and dementia: a meta-analysis}}, journal = {JAMA}, year = {2010}, doi = {10.1001/jama.2010.1013}, pmid = {20664045}, url = {https://doi.org/10.1001/jama.2010.1013} } @article{rapp2003-12771113, author = {Rapp, SR. and Espeland, M. A. and Shumaker, S. A. and Henderson, V. W. and Brunner, R. L. and Manson, J. E. and Gass, M. L. and Stefanick, M. L. and others}, title = {{Effect of estrogen plus progestin on global cognitive function in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial}}, journal = {JAMA}, year = {2003}, doi = {10.1001/jama.289.20.2663}, pmid = {12771113}, url = {https://doi.org/10.1001/jama.289.20.2663} } @article{tariot2004-14734594, author = {Tariot, P. N. and Farlow, M. R. and Grossberg, G. T. and Graham, S. M. and McDonald, S. and Gergel, I. and {Memantine Study Group}}, title = {{Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: a randomized controlled trial}}, journal = {JAMA}, year = {2004}, doi = {10.1001/jama.291.3.317}, pmid = {14734594}, url = {https://doi.org/10.1001/jama.291.3.317} } @article{lautenschlager2008-18768414, author = {Lautenschlager, N. T. and Cox, K. L. and Flicker, L. and Foster, J. K. and van Bockxmeer, F. M. and Xiao, J. and Greenop, K. R. and Almeida, O. P.}, title = {{Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial}}, journal = {JAMA}, year = {2008}, doi = {10.1001/jama.300.9.1027}, pmid = {18768414}, url = {https://doi.org/10.1001/jama.300.9.1027} } @article{quinn2010-21045096, author = {Quinn, J. F. and Raman, R. and Thomas, R. G. and Yurko-Mauro, K. and Nelson, E. B. and Van Dyck, C. and Galvin, J. E. and Emond, J. and others}, title = {{Docosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: a randomized trial}}, journal = {JAMA}, year = {2010}, doi = {10.1001/jama.2010.1510}, pmid = {21045096}, url = {https://doi.org/10.1001/jama.2010.1510} } @article{green2009-20009055, author = {Green, R. C. and Schneider, L. S. and Amato, D. A. and Beelen, A. P. and Wilcock, G. and Swabb, E. A. and Zavitz, K. H. and {Tarenflurbil Phase 3 Study Group}}, title = {{Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: a randomized controlled trial}}, journal = {JAMA}, year = {2009}, doi = {10.1001/jama.2009.1866}, pmid = {20009055}, url = {https://doi.org/10.1001/jama.2009.1866} } @article{manson2013-24084921, author = {Manson, J. E. and Chlebowski, R. T. and Stefanick, M. L. and Aragaki, A. K. and Rossouw, J. E. and Prentice, R. L. and Anderson, G. and Howard, B. V. and others}, title = {{Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the Women's Health Initiative randomized trials}}, journal = {JAMA}, year = {2013}, doi = {10.1001/jama.2013.278040}, pmid = {24084921}, url = {https://doi.org/10.1001/jama.2013.278040} } @article{shumaker2004-15213206, author = {Shumaker, S. A. and Legault, C. and Kuller, L. and Rapp, SR. and Thal, L. and Lane, D. S. and Fillit, H. and Stefanick, M. L. and others}, title = {{Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women: Women's Health Initiative Memory Study}}, journal = {JAMA}, year = {2004}, doi = {10.1001/jama.291.24.2947}, pmid = {15213206}, url = {https://doi.org/10.1001/jama.291.24.2947} } @article{espeland2004-15213207, author = {Espeland, M. A. and Rapp, SR. and Shumaker, S. A. and Brunner, R. and Manson, J. E. and Sherwin, B. B. and Hsia, J. and Margolis, K. L. and others}, title = {{Conjugated equine estrogens and global cognitive function in postmenopausal women: Women's Health Initiative Memory Study}}, journal = {JAMA}, year = {2004}, doi = {10.1001/jama.291.24.2959}, pmid = {15213207}, url = {https://doi.org/10.1001/jama.291.24.2959} } @article{reuben2025-39878968, author = {Reuben, D. B. and Gill, T. M. and Stevens, A. and Williamson, J. and Volpi, E. and Lichtenstein, M. and Jennings, L. A. and others}, title = {{Health System, Community-Based, or Usual Dementia Care for Persons With Dementia and Caregivers: The D-CARE Randomized Clinical Trial}}, journal = {JAMA}, year = {2025}, doi = {10.1001/jama.2024.25056}, pmid = {39878968}, url = {https://doi.org/10.1001/jama.2024.25056} } @article{blazhenets2026-42441390, author = {Blazhenets, Ganna and Soleimani-Meigooni, David N and Chiotis, Konstantinos and Allen, Isabel E and Rabinovici, Gil D and La Joie, Renaud and {Meta-Centiloid Study Group} and Apostolova, Liana G and others}, title = {{Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis}}, journal = {JAMA}, year = {2026}, doi = {10.1001/jama.2026.13116}, pmid = {42441390}, url = {https://doi.org/10.1001/jama.2026.13116} } @article{lu2024-39068543, author = {Lu, Y. and Pike, JR. and Chen, J. and Walker, K. A. and Sullivan, K. J. and Thyagarajan, B. and Mielke, M. M. and Lutsey, P. L. and Knopman, D. and Gottesman, R. F. and Sharrett, A. R. and Coresh, J. and others}, title = {{Changes in Alzheimer Disease Blood Biomarkers and Associations With Incident All-Cause Dementia}}, journal = {JAMA}, year = {2024}, doi = {10.1001/jama.2024.6619}, pmid = {39068543}, url = {https://doi.org/10.1001/jama.2024.6619} } @article{snitz2009-20040554, author = {Snitz, B. E. and O'Meara, E. S. and Carlson, M. C. and Arnold, A. M. and Ives, D. G. and Rapp, SR. and Saxton, J. and Lopez, O. L. and others}, title = {{Ginkgo biloba for preventing cognitive decline in older adults: a randomized trial}}, journal = {JAMA}, year = {2009}, doi = {10.1001/jama.2009.1913}, pmid = {20040554}, url = {https://doi.org/10.1001/jama.2009.1913} } @article{dysken2014-24381967, author = {Dysken, M. W. and Sano, M. and Asthana, S. and Vertrees, J. E. and Pallaki, M. and Llorente, M. and Love, S. and Schellenberg, G. D. and others}, title = {{Effect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trial}}, journal = {JAMA}, year = {2014}, doi = {10.1001/jama.2013.282834}, pmid = {24381967}, url = {https://doi.org/10.1001/jama.2013.282834} } @article{ball2002-12425704, author = {Ball, K. and Berch, D. B. and Helmers, K. F. and Jobe, J. B. and Leveck, M. D. and Marsiske, M. and Morris, J. N. and Rebok, G. W. and others}, title = {{Effects of cognitive training interventions with older adults: a randomized controlled trial}}, journal = {JAMA}, year = {2002}, doi = {10.1001/jama.288.18.2271}, pmid = {12425704}, url = {https://doi.org/10.1001/jama.288.18.2271} } @article{maher2011-21954480, author = {Maher, A. R. and Maglione, M. and Bagley, S. and Suttorp, M. and Hu, J. H. and Ewing, B. and Wang, Z. and Timmer, M. and others}, title = {{Efficacy and comparative effectiveness of atypical antipsychotic medications for off-label uses in adults: a systematic review and meta-analysis}}, journal = {JAMA}, year = {2011}, doi = {10.1001/jama.2011.1360}, pmid = {21954480}, url = {https://doi.org/10.1001/jama.2011.1360} } @article{knapp1994-8139083, author = {Knapp, M. J. and Knopman, D. S. and Solomon, P. R. and Pendlebury, W. W. and Davis, C. S. and Gracon, S. I.}, title = {{A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. The Tacrine Study Group}}, journal = {JAMA}, year = {1994}, doi = {10.1001/jama.1994.03510370037029}, pmid = {8139083}, url = {https://doi.org/10.1001/jama.1994.03510370037029} } @article{burgio1998-9863850, author = {Burgio, K. L. and Locher, J. L. and Goode, P. S. and Hardin, J. M. and McDowell, B. J. and Dombrowski, M. and Candib, D.}, title = {{Behavioral vs drug treatment for urge urinary incontinence in older women: a randomized controlled trial}}, journal = {JAMA}, year = {1998}, doi = {10.1001/jama.280.23.1995}, pmid = {9863850}, url = {https://doi.org/10.1001/jama.280.23.1995} } @article{kreijkampkaspers2004-15238592, author = {Kreijkamp-Kaspers, S. and Kok, L. and Grobbee, D. E. and de Haan, E. H. and Aleman, A. and Lampe, J. W. and van der Schouw, Y. T.}, title = {{Effect of soy protein containing isoflavones on cognitive function, bone mineral density, and plasma lipids in postmenopausal women: a randomized controlled trial}}, journal = {JAMA}, year = {2004}, doi = {10.1001/jama.292.1.65}, pmid = {15238592}, url = {https://doi.org/10.1001/jama.292.1.65} } @article{pomirchy2025-40267506, author = {Pomirchy, M. and Bommer, C. and Pradella, F. and Michalik, F. and Peters, R. and Geldsetzer, P.}, title = {{Herpes Zoster Vaccination and Dementia Occurrence (Australian natural experiment)}}, journal = {JAMA}, year = {2025}, doi = {10.1001/jama.2025.5013}, pmid = {40267506}, url = {https://doi.org/10.1001/jama.2025.5013} } @article{seshadri2010-20460622, author = {Seshadri, S. and Fitzpatrick, A. L. and Ikram, M. A. and DeStefano, A. L. and Gudnason, V. and Boada, M. and Bis, J. C. and Smith, A. V. and others}, title = {{Genome-wide analysis of genetic loci associated with Alzheimer disease}}, journal = {JAMA}, year = {2010}, doi = {10.1001/jama.2010.574}, pmid = {20460622}, url = {https://doi.org/10.1001/jama.2010.574} } @article{reitz2013-23571587, author = {Reitz, C. and Jun, G. and Naj, A. and Rajbhandary, R. and Vardarajan, B. N. and Wang, L. S. and Valladares, O. and Lin, C. F. and others}, title = {{Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans}}, journal = {JAMA}, year = {2013}, doi = {10.1001/jama.2013.2973}, pmid = {23571587}, url = {https://doi.org/10.1001/jama.2013.2973} } @article{aisen2008-18854539, author = {Aisen, P. S. and Schneider, L. S. and Sano, M. and Diaz-Arrastia, R. and van Dyck, C. H. and Weiner, M. F. and Bottiglieri, T. and Jin, S. and others}, title = {{High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial}}, journal = {JAMA}, year = {2008}, doi = {10.1001/jama.300.15.1774}, pmid = {18854539}, url = {https://doi.org/10.1001/jama.300.15.1774} } @article{atri2018-29318278, author = {Atri, A. and Frölich, L. and Ballard, C. and Tariot, P. N. and Molinuevo, J. L. and Boneva, N. and Windfeld, K. and Raket, L. L. and others}, title = {{Effect of Idalopirdine as Adjunct to Cholinesterase Inhibitors on Change in Cognition in Patients With Alzheimer Disease: Three Randomized Clinical Trials}}, journal = {JAMA}, year = {2018}, doi = {10.1001/jama.2017.20373}, pmid = {29318278}, url = {https://doi.org/10.1001/jama.2017.20373} } @article{lourida2019-31302669, author = {Lourida, I. and Hannon, E. and Littlejohns, T. J. and Langa, K. M. and Hyppönen, E. and Kuzma, E. and Llewellyn, D. J.}, title = {{Association of Lifestyle and Genetic Risk With Incidence of Dementia}}, journal = {JAMA}, year = {2019}, doi = {10.1001/jama.2019.9879}, pmid = {31302669}, url = {https://doi.org/10.1001/jama.2019.9879} } @article{adelman2014-24618967, author = {Adelman, R. D. and Tmanova, L. L. and Delgado, D. and Dion, S. and Lachs, M. S.}, title = {{Caregiver burden: a clinical review}}, journal = {JAMA}, year = {2014}, doi = {10.1001/jama.2014.304}, pmid = {24618967}, url = {https://doi.org/10.1001/jama.2014.304} } @article{lyketsos2002-12243634, author = {Lyketsos, C. G. and Lopez, O. and Jones, B. and Fitzpatrick, A. L. and Breitner, J. and DeKosky, S.}, title = {{Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study}}, journal = {JAMA}, year = {2002}, doi = {10.1001/jama.288.12.1475}, pmid = {12243634}, url = {https://doi.org/10.1001/jama.288.12.1475} } @article{sachs2025-39878993, author = {Sachs, G. A. and Johnson, N. M. and Gao, S. and Torke, A. M. and Hickman, S. E. and Pemberton, A. and Vrobel, A. and Pan, M. and West, J. and Kroenke, K.}, title = {{Palliative Care Program for Community-Dwelling Individuals With Dementia and Caregivers: The IN-PEACE Randomized Clinical Trial}}, journal = {JAMA}, year = {2025}, doi = {10.1001/jama.2024.25845}, pmid = {39878993}, url = {https://doi.org/10.1001/jama.2024.25845} } @article{palmqvist2020-32722745, author = {Palmqvist, S. and Janelidze, S. and Quiroz, Y. T. and Zetterberg, H. and Lopera, F. and Stomrud, E. and Su, Y. and Chen, Y. and others}, title = {{Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders}}, journal = {JAMA}, year = {2020}, doi = {10.1001/jama.2020.12134}, pmid = {32722745}, url = {https://doi.org/10.1001/jama.2020.12134} } @article{patnode2020-32096857, author = {Patnode, C. D. and Perdue, L. A. and Rossom, R. C. and Rushkin, M. C. and Redmond, N. and Thomas, R. G. and Lin, J. S.}, title = {{Screening for Cognitive Impairment in Older Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force}}, journal = {JAMA}, year = {2020}, doi = {10.1001/jama.2019.22258}, pmid = {32096857}, url = {https://doi.org/10.1001/jama.2019.22258} } @article{study2019-30688979, author = {{SPRINT MIND Investigators for the SPRINT Research Group} and Williamson, J. D. and Pajewski, N. M. and Auchus, A. P. and Bryan, R. N. and Chelune, G. and Cheung, A. K. and Cleveland, M. L. and others}, title = {{Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial}}, journal = {JAMA}, year = {2019}, doi = {10.1001/jama.2018.21442}, pmid = {30688979}, url = {https://doi.org/10.1001/jama.2018.21442} } @article{barbielliniamidei2021-33904867, author = {Barbiellini Amidei, C. and Fayosse, A. and Dumurgier, J. and Machado-Fragua, M. D. and Tabak, A. G. and van Sloten, T. and Kivimäki, M. and Dugravot, A. and others}, title = {{Association Between Age at Diabetes Onset and Subsequent Risk of Dementia}}, journal = {JAMA}, year = {2021}, doi = {10.1001/jama.2021.4001}, pmid = {33904867}, url = {https://doi.org/10.1001/jama.2021.4001} } @article{baker2025-f1551689, author = {Baker, L. D. and others}, title = {{Structured vs Self-Guided Multidomain Lifestyle Interventions for Global Cognitive Function: The US POINTER Randomized Clinical Trial}}, journal = {JAMA}, year = {2025}, pmid = {40720610} } @article{rabinovici2019-30938796, author = {Rabinovici, G. D. and Gatsonis, C. and Apgar, C. and Chaudhary, K. and Gareen, I. and Hanna, L. and Hendrix, J. and Hillner, B. E. and others}, title = {{Association of Amyloid Positron Emission Tomography With Subsequent Change in Clinical Management Among Medicare Beneficiaries With Mild Cognitive Impairment or Dementia}}, journal = {JAMA}, year = {2019}, doi = {10.1001/jama.2019.2000}, pmid = {30938796}, url = {https://doi.org/10.1001/jama.2019.2000} } @article{lebars1997-9343463, author = {Le Bars, P. L. and Katz, M. M. and Berman, N. and Itil, T. M. and Freedman, A. M. and Schatzberg, A. F.}, title = {{A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group}}, journal = {JAMA}, year = {1997}, doi = {10.1001/jama.278.16.1327}, pmid = {9343463}, url = {https://doi.org/10.1001/jama.278.16.1327} } @article{teno2013-23385273, author = {Teno, J. M. and Gozalo, P. L. and Bynum, J. P. and Leland, N. E. and Miller, S. C. and Morden, N. E. and Scupp, T. and Goodman, D. C. and others}, title = {{Change in end-of-life care for Medicare beneficiaries: site of death, place of care, and health care transitions in 2000, 2005, and 2009}}, journal = {JAMA}, year = {2013}, doi = {10.1001/jama.2012.207624}, pmid = {23385273}, url = {https://doi.org/10.1001/jama.2012.207624} } @article{moscoso2025-40522652, author = {Moscoso, Alexis and Heeman, Fiona and Raghavan, Sheelakumari and Costoya‐Sánchez, Alejandro and van Essen, Martijn and Mainta, Ismini and Camacho, Valle and Rodríguez-Fonseca, Omar Darío and others}, title = {{Frequency and Clinical Outcomes Associated With Tau Positron Emission Tomography Positivity}}, journal = {JAMA}, year = {2025}, doi = {10.1001/jama.2025.7817}, pmid = {40522652}, url = {https://doi.org/10.1001/jama.2025.7817} } @article{trinh2003-12517232, author = {Trinh, N. H. and Hoblyn, J. and Mohanty, S. and Yaffe, K.}, title = {{Efficacy of cholinesterase inhibitors in the treatment of neuropsychiatric symptoms and functional impairment in Alzheimer disease: a meta-analysis}}, journal = {JAMA}, year = {2003}, doi = {10.1001/jama.289.2.210}, pmid = {12517232}, url = {https://doi.org/10.1001/jama.289.2.210} } @article{gottesman2017-28399252, author = {Gottesman, R. F. and Schneider, A. L. and Zhou, Y. and Coresh, J. and Green, E. and Gupta, N. and Knopman, D. S. and Mintz, A. and others}, title = {{Association Between Midlife Vascular Risk Factors and Estimated Brain Amyloid Deposition}}, journal = {JAMA}, year = {2017}, doi = {10.1001/jama.2017.3090}, pmid = {28399252}, url = {https://doi.org/10.1001/jama.2017.3090} } @article{teri2003-14559955, author = {Teri, L. and Gibbons, L. E. and McCurry, S. M. and Logsdon, R. G. and Buchner, D. M. and Barlow, W. E. and Kukull, W. A. and LaCroix, A. Z. and others}, title = {{Exercise plus behavioral management in patients with Alzheimer disease: a randomized controlled trial}}, journal = {JAMA}, year = {2003}, doi = {10.1001/jama.290.15.2015}, pmid = {14559955}, url = {https://doi.org/10.1001/jama.290.15.2015} } @article{cummings2015-26393847, author = {Cummings, J. L. and Lyketsos, C. G. and Peskind, E. R. and Porsteinsson, A. P. and Mintzer, J. E. and Scharre, D. W. and De La Gandara, J. E. and Agronin, M. and others}, title = {{Effect of Dextromethorphan-Quinidine on Agitation in Patients With Alzheimer Disease Dementia: A Randomized Clinical Trial}}, journal = {JAMA}, year = {2015}, doi = {10.1001/jama.2015.10214}, pmid = {26393847}, url = {https://doi.org/10.1001/jama.2015.10214} } @article{baker2025-40720610, author = {Baker, L. D. and Espeland, M. A. and Whitmer, R. A. and Snyder, H. M. and Leng, X. and Lovato, L. and Papp, K. V. and Yu, M. and others}, title = {{Structured vs Self-Guided Multidomain Lifestyle Interventions for Global Cognitive Function: The US POINTER Randomized Clinical Trial}}, journal = {JAMA}, year = {2025}, doi = {10.1001/jama.2025.12923}, pmid = {40720610}, url = {https://doi.org/10.1001/jama.2025.12923} } @article{mattsson2009-19622817, author = {Mattsson, N. and Zetterberg, H. and Hansson, O. and Andreasen, N. and Parnetti, L. and Jonsson, M. and Herukka, S. K. and van der Flier, W. M. and others}, title = {{CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment}}, journal = {JAMA}, year = {2009}, doi = {10.1001/jama.2009.1064}, pmid = {19622817}, url = {https://doi.org/10.1001/jama.2009.1064} } @article{quinn2020-33048152, author = {Quinn, K. L. and Shurrab, M. and Gitau, K. and Kavalieratos, D. and Isenberg, SR. and Stall, N. M. and Stukel, T. A. and Goldman, R. and others}, title = {{Association of Receipt of Palliative Care Interventions With Health Care Use, Quality of Life, and Symptom Burden Among Adults With Chronic Noncancer Illness: A Systematic Review and Meta-analysis}}, journal = {JAMA}, year = {2020}, doi = {10.1001/jama.2020.14205}, pmid = {33048152}, url = {https://doi.org/10.1001/jama.2020.14205} } @article{reade2016-26975647, author = {Reade, M. C. and Eastwood, G. M. and Bellomo, R. and Bailey, M. and Bersten, A. and Cheung, B. and Davies, A. and Delaney, A. and others}, title = {{Effect of Dexmedetomidine Added to Standard Care on Ventilator-Free Time in Patients With Agitated Delirium: A Randomized Clinical Trial}}, journal = {JAMA}, year = {2016}, doi = {10.1001/jama.2016.2707}, pmid = {26975647}, url = {https://doi.org/10.1001/jama.2016.2707} } @article{sims2023-9857475c, author = {Sims, JR. and Zimmer, J. A. and Evans, C. D. and Lu, M. and Ardayfio, P. and Sparks, J. and Wessels, A. M. and Shcherbinin, S. and Wang, H. and Monkul Nery, E. S. and Collins, E. C. and Solomon, P. and Salloway, S. and Apostolova, L. G. and Hansson, O. and Ritchie, C. and Brooks, D. A. and Mintun, M. and Skovronsky, D. M. and {TRAILBLAZER-ALZ 2 Investigators}}, title = {{Donanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial}}, journal = {JAMA}, year = {2023}, pmid = {37459141} } @article{sims2023-37459141, author = {Sims, JR. and Zimmer, J. A. and Evans, C. D. and Lu, M. and Ardayfio, P. and Sparks, J. and Wessels, A. M. and Shcherbinin, S. and others}, title = {{Donanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial}}, journal = {JAMA}, year = {2023}, doi = {10.1001/jama.2023.13239}, pmid = {37459141}, url = {https://doi.org/10.1001/jama.2023.13239} } @article{kornblith2022-35438728, author = {Kornblith, E. and Bahorik, A. and Boscardin, W. J. and Xia, F. and Barnes, D. E. and Yaffe, K.}, title = {{Association of Race and Ethnicity With Incidence of Dementia Among Older Adults}}, journal = {JAMA}, year = {2022}, doi = {10.1001/jama.2022.3550}, pmid = {35438728}, url = {https://doi.org/10.1001/jama.2022.3550} } @article{whitmer2009-19366776, author = {Whitmer, R. A. and Karter, A. J. and Yaffe, K. and Quesenberry, C. P. and Selby, J. V.}, title = {{Hypoglycemic episodes and risk of dementia in older patients with type 2 diabetes mellitus}}, journal = {JAMA}, year = {2009}, doi = {10.1001/jama.2009.460}, pmid = {19366776}, url = {https://doi.org/10.1001/jama.2009.460} } @article{ely2004-15082703, author = {Ely, E. W. and Shintani, A. and Truman, B. and Speroff, T. and Gordon, S. M. and Harrell, F. E. and Inouye, S. K. and Bernard, G. R. and others}, title = {{Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit}}, journal = {JAMA}, year = {2004}, doi = {10.1001/jama.291.14.1753}, pmid = {15082703}, url = {https://doi.org/10.1001/jama.291.14.1753} } @article{zhang2026-41661604, author = {Zhang, Y. and Liu, Y. and Li, Y. and Gu, X. and Kang, J. H. and others}, title = {{Coffee and Tea Intake, Dementia Risk, and Cognitive Function}}, journal = {JAMA}, year = {2026}, doi = {10.1001/jama.2025.27259}, pmid = {41661604}, url = {https://doi.org/10.1001/jama.2025.27259} } @article{leguen2023-36809323, author = {Le Guen, Y. and Raulin, A. C. and Logue, M. W. and Sherva, R. and Belloy, M. E. and Eger, S. J. and Chen, A. and Kennedy, G. and Kuchenbecker, L. and O'Leary, J. P. and Zhang, R. and Merritt, V. C. and others}, title = {{Association of African Ancestry-Specific APOE Missense Variant R145C With Risk of Alzheimer Disease}}, journal = {JAMA}, year = {2023}, doi = {10.1001/jama.2023.0268}, pmid = {36809323}, url = {https://doi.org/10.1001/jama.2023.0268} } @article{mittelman1996-8940320, author = {Mittelman, M. S. and Ferris, S. H. and Shulman, E. and Steinberg, G. and Levin, B.}, title = {{A family intervention to delay nursing home placement of patients with Alzheimer disease. A randomized controlled trial}}, journal = {JAMA}, year = {1996}, doi = {10.1001/jama.1996.03540210033030}, pmid = {8940320}, url = {https://doi.org/10.1001/jama.1996.03540210033030} } @article{chew2015-26305649, author = {Chew, E. Y. and Clemons, T. E. and Agrón, E. and Launer, L. J. and Grodstein, F. and Bernstein, P. S.}, title = {{Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial}}, journal = {JAMA}, year = {2015}, doi = {10.1001/jama.2015.9677}, pmid = {26305649}, url = {https://doi.org/10.1001/jama.2015.9677} } @article{donohue2017-28609533, author = {Donohue, M. C. and Sperling, R. A. and Petersen, R. and Sun, C. K. and Weiner, M. W. and Aisen, P. S. and {Alzheimer’s Disease Neuroimaging Initiative}}, title = {{Association Between Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons}}, journal = {JAMA}, year = {2017}, doi = {10.1001/jama.2017.6669}, pmid = {28609533}, url = {https://doi.org/10.1001/jama.2017.6669} } @article{devanand2026-41405855, author = {Devanand, D P and Wisniewski, Thomas and Razlighi, Qolamreza and Qian, Min and Wei, Renjie and Andrews, Howard F and Acosta, Edward P and Bell, Karen L and others}, title = {{Valacyclovir Treatment of Early Symptomatic Alzheimer Disease: The VALAD Randomized Clinical Trial}}, journal = {JAMA}, year = {2026}, doi = {10.1001/jama.2025.21738}, pmid = {41405855}, url = {https://doi.org/10.1001/jama.2025.21738} } @article{palmqvist2024-39068545, author = {Palmqvist, S. and Tideman, P. and Mattsson-Carlgren, N. and Schindler, S. E. and Smith, R. and Ossenkoppele, R. and Calling, S. and West, T. and others}, title = {{Blood Biomarkers to Detect Alzheimer Disease in Primary Care and Secondary Care}}, journal = {JAMA}, year = {2024}, doi = {10.1001/jama.2024.13855}, pmid = {39068545}, url = {https://doi.org/10.1001/jama.2024.13855} } @article{shumaker2003-12771112, author = {Shumaker, S. A. and Legault, C. and Rapp, SR. and Thal, L. and Wallace, R. B. and Ockene, J. K. and Hendrix, S. L. and Jones, B. N. and others}, title = {{Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial}}, journal = {JAMA}, year = {2003}, doi = {10.1001/jama.289.20.2651}, pmid = {12771112}, url = {https://doi.org/10.1001/jama.289.20.2651} } @article{ely2001-11730446, author = {Ely, E. W. and Inouye, S. K. and Bernard, G. R. and Gordon, S. and Francis, J. and May, L. and Truman, B. and Speroff, T. and others}, title = {{Delirium in mechanically ventilated patients: validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU)}}, journal = {JAMA}, year = {2001}, doi = {10.1001/jama.286.21.2703}, pmid = {11730446}, url = {https://doi.org/10.1001/jama.286.21.2703} } @article{gitlin2010-20810376, author = {Gitlin, L. N. and Winter, L. and Dennis, M. P. and Hodgson, N. and Hauck, W. W.}, title = {{A biobehavioral home-based intervention and the well-being of patients with dementia and their caregivers: the COPE randomized trial}}, journal = {JAMA}, year = {2010}, doi = {10.1001/jama.2010.1253}, pmid = {20810376}, url = {https://doi.org/10.1001/jama.2010.1253} } @article{samieri2018-30140876, author = {Samieri, C. and Perier, M. C. and Gaye, B. and Proust-Lima, C. and Helmer, C. and Dartigues, J. F. and Berr, C. and Tzourio, C. and others}, title = {{Association of Cardiovascular Health Level in Older Age With Cognitive Decline and Incident Dementia}}, journal = {JAMA}, year = {2018}, doi = {10.1001/jama.2018.11499}, pmid = {30140876}, url = {https://doi.org/10.1001/jama.2018.11499} } @article{scarmeas2009-19671904, author = {Scarmeas, N. and Luchsinger, J. A. and Schupf, N. and Brickman, A. M. and Cosentino, S. and Tang, M. X. and Stern, Y.}, title = {{Physical activity, diet, and risk of Alzheimer disease}}, journal = {JAMA}, year = {2009}, doi = {10.1001/jama.2009.1144}, pmid = {19671904}, url = {https://doi.org/10.1001/jama.2009.1144} } @article{silverman2001-11694153, author = {Silverman, D. H. and Small, G. W. and Chang, C. Y. and Lu, C. S. and Kung De Aburto, M. A. and Chen, W. and Czernin, J. and Rapoport, S. I. and others}, title = {{Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome}}, journal = {JAMA}, year = {2001}, doi = {10.1001/jama.286.17.2120}, pmid = {11694153}, url = {https://doi.org/10.1001/jama.286.17.2120} } @article{ossenkoppele2018-30326496, author = {Ossenkoppele, R. and Rabinovici, G. D. and Smith, R. and Cho, H. and Schöll, M. and Strandberg, O. and Palmqvist, S. and Mattsson, N. and others}, title = {{Discriminative Accuracy of [18F]flortaucipir Positron Emission Tomography for Alzheimer Disease vs Other Neurodegenerative Disorders}}, journal = {JAMA}, year = {2018}, doi = {10.1001/jama.2018.12917}, pmid = {30326496}, url = {https://doi.org/10.1001/jama.2018.12917} } @article{phelan2012-22235087, author = {Phelan, E. A. and Borson, S. and Grothaus, L. and Balch, S. and Larson, E. B.}, title = {{Association of incident dementia with hospitalizations}}, journal = {JAMA}, year = {2012}, doi = {10.1001/jama.2011.1964}, pmid = {22235087}, url = {https://doi.org/10.1001/jama.2011.1964} } @article{ehlenbach2010-20179286, author = {Ehlenbach, W. J. and Hough, C. L. and Crane, P. K. and Haneuse, S. J. and Carson, S. S. and Curtis, JR. and Larson, E. B.}, title = {{Association between acute care and critical illness hospitalization and cognitive function in older adults}}, journal = {JAMA}, year = {2010}, doi = {10.1001/jama.2010.167}, pmid = {20179286}, url = {https://doi.org/10.1001/jama.2010.167} } @article{mukamal2003-12636463, author = {Mukamal, K. J. and Kuller, L. H. and Fitzpatrick, A. L. and Longstreth, W. T. and Mittleman, M. A. and Siscovick, D. S.}, title = {{Prospective study of alcohol consumption and risk of dementia in older adults}}, journal = {JAMA}, year = {2003}, doi = {10.1001/jama.289.11.1405}, pmid = {12636463}, url = {https://doi.org/10.1001/jama.289.11.1405} } @article{riemersmavanderlek2008-18544724, author = {Riemersma-van der Lek, R. F. and Swaab, D. F. and Twisk, J. and Hol, E. M. and Hoogendijk, W. J. and Van Someren, E. J.}, title = {{Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial}}, journal = {JAMA}, year = {2008}, doi = {10.1001/jama.299.22.2642}, pmid = {18544724}, url = {https://doi.org/10.1001/jama.299.22.2642} } @article{walker2019-31408138, author = {Walker, K. A. and Sharrett, A. R. and Wu, A. and Schneider, A. L. C. and Albert, M. and Lutsey, P. L. and Bandeen-Roche, K. and Coresh, J. and others}, title = {{Association of Midlife to Late-Life Blood Pressure Patterns With Incident Dementia}}, journal = {JAMA}, year = {2019}, doi = {10.1001/jama.2019.10575}, pmid = {31408138}, url = {https://doi.org/10.1001/jama.2019.10575} } @article{yaffe2011-21828324, author = {Yaffe, K. and Laffan, A. M. and Harrison, S. L. and Redline, S. and Spira, A. P. and Ensrud, K. E. and Ancoli-Israel, S. and Stone, K. L.}, title = {{Sleep-disordered breathing, hypoxia, and risk of mild cognitive impairment and dementia in older women}}, journal = {JAMA}, year = {2011}, doi = {10.1001/jama.2011.1115}, pmid = {21828324}, url = {https://doi.org/10.1001/jama.2011.1115} } @article{mitchell2004-15187055, author = {Mitchell, S. L. and Kiely, D. K. and Hamel, M. B. and Park, P. S. and Morris, J. N. and Fries, B. E.}, title = {{Estimating prognosis for nursing home residents with advanced dementia}}, journal = {JAMA}, year = {2004}, doi = {10.1001/jama.291.22.2734}, pmid = {15187055}, url = {https://doi.org/10.1001/jama.291.22.2734} } @article{hendrie2001-11176911, author = {Hendrie, H. C. and Ogunniyi, A. and Hall, K. S. and Baiyewu, O. and Unverzagt, F. W. and Gureje, O. and Gao, S. and Evans, R. M. and others}, title = {{Incidence of dementia and Alzheimer disease in 2 communities: Yoruba residing in Ibadan, Nigeria, and African Americans residing in Indianapolis, Indiana}}, journal = {JAMA}, year = {2001}, doi = {10.1001/jama.285.6.739}, pmid = {11176911}, url = {https://doi.org/10.1001/jama.285.6.739} } @article{jack2019-31211344, author = {Jack, C. R. and Wiste, H. J. and Therneau, T. M. and Weigand, S. D. and Knopman, D. S. and Mielke, M. M. and Lowe, V. J. and Vemuri, P. and others}, title = {{Associations of Amyloid, Tau, and Neurodegeneration Biomarker Profiles With Rates of Memory Decline Among Individuals Without Dementia}}, journal = {JAMA}, year = {2019}, doi = {10.1001/jama.2019.7437}, pmid = {31211344}, url = {https://doi.org/10.1001/jama.2019.7437} } @article{farrer1997-9343467, author = {Farrer, L. A. and Cupples, L. A. and Haines, J. L. and Hyman, B. and Kukull, W. A. and Mayeux, R. and Myers, R. H. and Pericak-Vance, M. A. and others}, title = {{Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium}}, journal = {JAMA}, year = {1997}, doi = {10.1001/jama.1997.03550160069041}, pmid = {9343467}, url = {https://doi.org/10.1001/jama.1997.03550160069041} } @article{tang1998-9508150, author = {Tang, M. X. and Stern, Y. and Marder, K. and Bell, K. and Gurland, B. and Lantigua, R. and Andrews, H. and Feng, L. and others}, title = {{The APOE-epsilon4 allele and the risk of Alzheimer disease among African Americans, whites, and Hispanics}}, journal = {JAMA}, year = {1998}, doi = {10.1001/jama.279.10.751}, pmid = {9508150}, url = {https://doi.org/10.1001/jama.279.10.751} } @article{yaffe1998-9496988, author = {Yaffe, K. and Sawaya, G. and Lieberburg, I. and Grady, D.}, title = {{Estrogen therapy in postmenopausal women: effects on cognitive function and dementia}}, journal = {JAMA}, year = {1998}, doi = {10.1001/jama.279.9.688}, pmid = {9496988}, url = {https://doi.org/10.1001/jama.279.9.688} } @article{wilson2002-11851541, author = {Wilson, R. S. and Mendes De Leon, C. F. and Barnes, L. L. and Schneider, J. A. and Bienias, J. L. and Evans, D. A. and Bennett, D. A.}, title = {{Participation in cognitively stimulating activities and risk of incident Alzheimer disease}}, journal = {JAMA}, year = {2002}, doi = {10.1001/jama.287.6.742}, pmid = {11851541}, url = {https://doi.org/10.1001/jama.287.6.742} } @article{engelhart2002-12076218, author = {Engelhart, M. J. and Geerlings, M. I. and Ruitenberg, A. and van Swieten, J. C. and Hofman, A. and Witteman, J. C. and Breteler, M. M.}, title = {{Dietary intake of antioxidants and risk of Alzheimer disease}}, journal = {JAMA}, year = {2002}, doi = {10.1001/jama.287.24.3223}, pmid = {12076218}, url = {https://doi.org/10.1001/jama.287.24.3223} } @article{feart2009-19671905, author = {Féart, C. and Samieri, C. and Rondeau, V. and Amieva, H. and Portet, F. and Dartigues, J. F. and Scarmeas, N. and Barberger-Gateau, P.}, title = {{Adherence to a Mediterranean diet, cognitive decline, and risk of dementia}}, journal = {JAMA}, year = {2009}, doi = {10.1001/jama.2009.1146}, pmid = {19671905}, url = {https://doi.org/10.1001/jama.2009.1146} } @article{stern1994-8139057, author = {Stern, Y. and Gurland, B. and Tatemichi, T. K. and Tang, M. X. and Wilder, D. and Mayeux, R.}, title = {{Influence of education and occupation on the incidence of Alzheimer's disease}}, journal = {JAMA}, year = {1994}, doi = {10.1001/jama.1994.03510370056032}, pmid = {8139057}, url = {https://doi.org/10.1001/jama.1994.03510370056032} } @article{sink2005-15687315, author = {Sink, K. M. and Holden, K. F. and Yaffe, K.}, title = {{Pharmacological treatment of neuropsychiatric symptoms of dementia: a review of the evidence}}, journal = {JAMA}, year = {2005}, doi = {10.1001/jama.293.5.596}, pmid = {15687315}, url = {https://doi.org/10.1001/jama.293.5.596} } @article{farlow1992-1404819, author = {Farlow, M. and Gracon, S. I. and Hershey, L. A. and Lewis, K. W. and Sadowsky, C. H. and Dolan-Ureno, J.}, title = {{A controlled trial of tacrine in Alzheimer's disease. The Tacrine Study Group}}, journal = {JAMA}, year = {1992}, doi = {10.1001/jama.1992.03490180055026}, pmid = {1404819}, url = {https://doi.org/10.1001/jama.1992.03490180055026} } @article{murray2013-23842577, author = {Murray, C. J. and Atkinson, C. and Bhalla, K. and Birbeck, G. and Burstein, R. and Chou, D. and Dellavalle, R. and Danaei, G. and others}, title = {{The state of US health, 1990-2010: burden of diseases, injuries, and risk factors}}, journal = {JAMA}, year = {2013}, doi = {10.1001/jama.2013.13805}, pmid = {23842577}, url = {https://doi.org/10.1001/jama.2013.13805} } @article{tideman2024-e791e2c1, author = {Tideman, Pontus and Mattsson-Carlgren, Niklas and Schindler, Suzanne E. and Smith, Ruben and Ossenkoppele, Rik and Calling, Susanna and West, Tim and Monane, Mark and Verghese, Philip B. and Braunstein, Joel B. and Blennow, Kaj and Janelidze, Shorena and Stomrud, Erik and Salvadó, Gemma and Hansson, Oskar and Palmqvist, Sebastian}, title = {{Blood Biomarkers to Detect Alzheimer Disease in Primary Care and Secondary Care}}, journal = {JAMA}, year = {2024}, pmid = {39068545} } @article{nelson2002-12186605, author = {Nelson, H. D. and Humphrey, L. L. and Nygren, P. and Teutsch, S. M. and Allan, J. D.}, title = {{Postmenopausal hormone replacement therapy: scientific review}}, journal = {JAMA}, year = {2002}, doi = {10.1001/jama.288.7.872}, pmid = {12186605}, url = {https://doi.org/10.1001/jama.288.7.872} } @article{petersen1995-7646655, author = {Petersen, R. C. and Smith, G. E. and Ivnik, R. J. and Tangalos, E. G. and Schaid, D. J. and Thibodeau, S. N. and Kokmen, E. and Waring, S. C. and others}, title = {{Apolipoprotein E status as a predictor of the development of Alzheimer's disease in memory-impaired individuals}}, journal = {JAMA}, year = {1995}, doi = {10.1001/jama.1995.03520400044042}, pmid = {7646655}, url = {https://doi.org/10.1001/jama.1995.03520400044042} } @article{leblanc2001-11255426, author = {LeBlanc, E. S. and Janowsky, J. and Chan, B. K. and Nelson, H. D.}, title = {{Hormone replacement therapy and cognition: systematic review and meta-analysis}}, journal = {JAMA}, year = {2001}, doi = {10.1001/jama.285.11.1489}, pmid = {11255426}, url = {https://doi.org/10.1001/jama.285.11.1489} } @article{buckley2026-42449500, author = {Buckley, Rachel F and Townsend, Diana L and Birkenbihl, Colin J and Cuppels, Madison and Coughlan, Gillian T and Seto, Mabel T and Brown, Jane A and Properzi, Michael J and others}, title = {{Prognostic Value of Blood-Based P-Tau217 Levels for Progression to Cognitive Impairment}}, journal = {JAMA}, year = {2026}, doi = {10.1001/jama.2026.12556}, pmid = {42449500}, url = {https://doi.org/10.1001/jama.2026.12556} } @article{mulnard2000-10697060, author = {Mulnard, R. A. and Cotman, C. W. and Kawas, C. and van Dyck, C. H. and Sano, M. and Doody, R. and Koss, E. and Pfeiffer, E. and others}, title = {{Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: a randomized controlled trial. Alzheimer's Disease Cooperative Study}}, journal = {JAMA}, year = {2000}, doi = {10.1001/jama.283.8.1007}, pmid = {10697060}, url = {https://doi.org/10.1001/jama.283.8.1007} } @article{clark2011-21245183, author = {Clark, C. M. and Schneider, J. A. and Bedell, B. J. and Beach, T. G. and Bilker, W. B. and Mintun, M. A. and Pontecorvo, M. J. and Hefti, F. and others}, title = {{Use of florbetapir-PET for imaging beta-amyloid pathology}}, journal = {JAMA}, year = {2011}, doi = {10.1001/jama.2010.2008}, pmid = {21245183}, url = {https://doi.org/10.1001/jama.2010.2008} } @article{wang2022-35315884, author = {Wang, W. and Zhang, M. J. and Inciardi, R. M. and Norby, F. L. and Johansen, M. C. and Parikh, R. and Hof, JR., Van't and Alonso, A. and others}, title = {{Association of Echocardiographic Measures of Left Atrial Function and Size With Incident Dementia}}, journal = {JAMA}, year = {2022}, doi = {10.1001/jama.2022.2518}, pmid = {35315884}, url = {https://doi.org/10.1001/jama.2022.2518} } @article{schulz1999-28eb29b7, author = {Schulz, R. and Beach, SR.}, title = {{Caregiving as a Risk Factor for Mortality: The Caregiver Health Effects Study}}, journal = {JAMA}, year = {1999}, pmid = {10605972} } @article{slooter1997-9052712, author = {Slooter, A. J. and Tang, M. X. and van Duijn, C. M. and Stern, Y. and Ott, A. and Bell, K. and Breteler, M. M. and Van Broeckhoven, C. and others}, title = {{Apolipoprotein E epsilon4 and the risk of dementia with stroke. A population-based investigation}}, journal = {JAMA}, year = {1997}, doi = {10.1001/jama.277.10.818}, pmid = {9052712}, url = {https://doi.org/10.1001/jama.277.10.818} } @article{callahan2006-16684985, author = {Callahan, C. M. and Boustani, M. A. and Unverzagt, F. W. and Austrom, M. G. and Damush, T. M. and Perkins, A. J. and Fultz, B. A. and Hui, S. L. and others}, title = {{Effectiveness of collaborative care for older adults with Alzheimer disease in primary care: a randomized controlled trial}}, journal = {JAMA}, year = {2006}, doi = {10.1001/jama.295.18.2148}, pmid = {16684985}, url = {https://doi.org/10.1001/jama.295.18.2148} } @article{langa2004-15598922, author = {Langa, K. M. and Foster, N. L. and Larson, E. B.}, title = {{Mixed dementia: emerging concepts and therapeutic implications}}, journal = {JAMA}, year = {2004}, doi = {10.1001/jama.292.23.2901}, pmid = {15598922}, url = {https://doi.org/10.1001/jama.292.23.2901} } @article{li2022-34928310, author = {Li, T. and Li, J. and Yuan, L. and Wu, J. and Jiang, C. and Daniels, J. and Mehta, R. L. and Wang, M. and others}, title = {{Effect of Regional vs General Anesthesia on Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery: The RAGA Randomized Trial}}, journal = {JAMA}, year = {2022}, doi = {10.1001/jama.2021.22647}, pmid = {34928310}, url = {https://doi.org/10.1001/jama.2021.22647} } @article{stern1997-9052710, author = {Stern, Y. and Tang, M. X. and Albert, M. S. and Brandt, J. and Jacobs, D. M. and Bell, K. and Marder, K. and Sano, M. and others}, title = {{Predicting time to nursing home care and death in individuals with Alzheimer disease}}, journal = {JAMA}, year = {1997}, doi = {10.1001/jama.1997.03540340040030}, pmid = {9052710}, url = {https://doi.org/10.1001/jama.1997.03540340040030} } @article{small1995-7884953, author = {Small, G. W. and Mazziotta, J. C. and Collins, M. T. and Baxter, L. R. and Phelps, M. E. and Mandelkern, M. A. and Kaplan, A. and La Rue, A. and others}, title = {{Apolipoprotein E type 4 allele and cerebral glucose metabolism in relatives at risk for familial Alzheimer disease}}, journal = {JAMA}, year = {1995}, doi = {10.1001/jama.1995.03520360056039}, pmid = {7884953}, url = {https://doi.org/10.1001/jama.1995.03520360056039} } @article{morris2016-26836731, author = {Morris, M. C. and Brockman, J. and Schneider, J. A. and Wang, Y. and Bennett, D. A. and Tangney, C. C. and van de Rest, O.}, title = {{Association of Seafood Consumption, Brain Mercury Level, and APOE ε4 Status With Brain Neuropathology in Older Adults}}, journal = {JAMA}, year = {2016}, doi = {10.1001/jama.2015.19451}, pmid = {26836731}, url = {https://doi.org/10.1001/jama.2015.19451} } @article{yaffe2004-15536110, author = {Yaffe, K. and Kanaya, A. and Lindquist, K. and Simonsick, E. M. and Harris, T. and Shorr, R. I. and Tylavsky, F. A. and Newman, A. B.}, title = {{The metabolic syndrome, inflammation, and risk of cognitive decline}}, journal = {JAMA}, year = {2004}, doi = {10.1001/jama.292.18.2237}, pmid = {15536110}, url = {https://doi.org/10.1001/jama.292.18.2237} } @article{curtis2023-37210665, author = {Curtis, JR. and Lee, R. Y. and Brumback, L. C. and Kross, E. K. and Downey, L. and Torrence, J. and LeDuc, N. and Mallon Andrews, K. and others}, title = {{Intervention to Promote Communication About Goals of Care for Hospitalized Patients With Serious Illness: A Randomized Clinical Trial}}, journal = {JAMA}, year = {2023}, doi = {10.1001/jama.2023.8812}, pmid = {37210665}, url = {https://doi.org/10.1001/jama.2023.8812} } @article{lee2003-14625335, author = {Lee, D. S. and Austin, P. C. and Rouleau, J. L. and Liu, P. P. and Naimark, D. and Tu, J. V.}, title = {{Predicting mortality among patients hospitalized for heart failure: derivation and validation of a clinical model}}, journal = {JAMA}, year = {2003}, doi = {10.1001/jama.290.19.2581}, pmid = {14625335}, url = {https://doi.org/10.1001/jama.290.19.2581} } @article{haan1999-10404910, author = {Haan, M. N. and Shemanski, L. and Jagust, W. J. and Manolio, T. A. and Kuller, L.}, title = {{The role of APOE epsilon4 in modulating effects of other risk factors for cognitive decline in elderly persons}}, journal = {JAMA}, year = {1999}, doi = {10.1001/jama.282.1.40}, pmid = {10404910}, url = {https://doi.org/10.1001/jama.282.1.40} } @article{fleisher2026-42441396, author = {Fleisher, Adam S and Munsie, Leanne and Mancini, Michele and Cheng, Yun-Ju and Guo, Jiaying and Nuthall, Hugh and Otero, Diana Svaldi and Kotari, Vikas and others}, title = {{Ceperognastat in Early Symptomatic Alzheimer Disease: A Randomized Clinical Trial}}, journal = {JAMA}, year = {2026}, doi = {10.1001/jama.2026.12768}, pmid = {42441396}, url = {https://doi.org/10.1001/jama.2026.12768} } @article{yaffe2002-11966383, author = {Yaffe, K. and Fox, P. and Newcomer, R. and Sands, L. and Lindquist, K. and Dane, K. and Covinsky, K. E.}, title = {{Patient and caregiver characteristics and nursing home placement in patients with dementia}}, journal = {JAMA}, year = {2002}, doi = {10.1001/jama.287.16.2090}, pmid = {11966383}, url = {https://doi.org/10.1001/jama.287.16.2090} } @article{mathioudakis2025-41144242, author = {Mathioudakis, Nestoras Nicolas and Lalani, Benjamin and Abusamaan, Mohammed S. and Alderfer, Mary Ellen and Alver, Defne and Dobs, Adrian and Kane, Brian and others}, title = {{An AI-Powered Lifestyle Intervention vs Human Coaching in the Diabetes Prevention Program}}, journal = {JAMA}, year = {2025}, doi = {10.1001/jama.2025.19563}, pmid = {41144242}, url = {https://doi.org/10.1001/jama.2025.19563} } @article{morrison2000-10872012, author = {Morrison, R. S. and Siu, A. L.}, title = {{Survival in end-stage dementia following acute illness}}, journal = {JAMA}, year = {2000}, doi = {10.1001/jama.284.1.47}, pmid = {10872012}, url = {https://doi.org/10.1001/jama.284.1.47} } @article{raichlen2023-37698563, author = {Raichlen, D. A. and Aslan, D. H. and Sayre, M. K. and Bharadwaj, P. K. and Ally, M. and Maltagliati, S. and Lai, M. H. C. and Wilcox, R. R. and others}, title = {{Sedentary Behavior and Incident Dementia Among Older Adults}}, journal = {JAMA}, year = {2023}, doi = {10.1001/jama.2023.15231}, pmid = {37698563}, url = {https://doi.org/10.1001/jama.2023.15231} } @article{snowdon1997-9052711, author = {Snowdon, D. A. and Greiner, L. H. and Mortimer, J. A. and Riley, K. P. and Greiner, P. A. and Markesbery, W. R.}, title = {{Brain infarction and the clinical expression of Alzheimer disease. The Nun Study}}, journal = {JAMA}, year = {1997}, doi = {10.1001/jama.1997.03540340047031}, pmid = {9052711}, url = {https://doi.org/10.1001/jama.1997.03540340047031} } @article{benner2002-12132975, author = {Benner, J. S. and Glynn, R. J. and Mogun, H. and Neumann, P. J. and Weinstein, M. C. and Avorn, J.}, title = {{Long-term persistence in use of statin therapy in elderly patients}}, journal = {JAMA}, year = {2002}, doi = {10.1001/jama.288.4.455}, pmid = {12132975}, url = {https://doi.org/10.1001/jama.288.4.455} } @article{abbott2004-15383515, author = {Abbott, R. D. and White, L. R. and Ross, G. W. and Masaki, K. H. and Curb, J. D. and Petrovitch, H.}, title = {{Walking and dementia in physically capable elderly men}}, journal = {JAMA}, year = {2004}, doi = {10.1001/jama.292.12.1447}, pmid = {15383515}, url = {https://doi.org/10.1001/jama.292.12.1447} } @article{wachterman2011-21285424, author = {Wachterman, M. W. and Marcantonio, E. R. and Davis, R. B. and McCarthy, E. P.}, title = {{Association of hospice agency profit status with patient diagnosis, location of care, and length of stay}}, journal = {JAMA}, year = {2011}, doi = {10.1001/jama.2011.70}, pmid = {21285424}, url = {https://doi.org/10.1001/jama.2011.70} } @article{adelman2014-1b049335, author = {Adelman, R. D. and Tmanova, L. L. and Delgado, D. and Dion, S. and Lachs, M. S.}, title = {{Caregiver Burden: A Clinical Review}}, journal = {JAMA}, year = {2014}, pmid = {24618967} } @article{geerlings2001-11255424, author = {Geerlings, M. I. and Ruitenberg, A. and Witteman, J. C. and van Swieten, J. C. and Hofman, A. and van Duijn, C. M. and Breteler, M. M. and Launer, L. J.}, title = {{Reproductive period and risk of dementia in postmenopausal women}}, journal = {JAMA}, year = {2001}, doi = {10.1001/jama.285.11.1475}, pmid = {11255424}, url = {https://doi.org/10.1001/jama.285.11.1475} } @article{aisen2003-12783912, author = {Aisen, P. S. and Schafer, K. A. and Grundman, M. and Pfeiffer, E. and Sano, M. and Davis, K. L. and Farlow, M. R. and Jin, S. and others}, title = {{Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial}}, journal = {JAMA}, year = {2003}, doi = {10.1001/jama.289.21.2819}, pmid = {12783912}, url = {https://doi.org/10.1001/jama.289.21.2819} } @article{kadotani2001-11401610, author = {Kadotani, H. and Kadotani, T. and Young, T. and Peppard, P. E. and Finn, L. and Colrain, I. M. and Murphy, G. M. and Mignot, E.}, title = {{Association between apolipoprotein E epsilon4 and sleep-disordered breathing in adults}}, journal = {JAMA}, year = {2001}, doi = {10.1001/jama.285.22.2888}, pmid = {11401610}, url = {https://doi.org/10.1001/jama.285.22.2888} } @article{rogaeva1998-9718052, author = {Rogaeva, E. and Premkumar, S. and Song, Y. and Sorbi, S. and Brindle, N. and Paterson, A. and Duara, R. and Levesque, G. and others}, title = {{Evidence for an Alzheimer disease susceptibility locus on chromosome 12 and for further locus heterogeneity}}, journal = {JAMA}, year = {1998}, doi = {10.1001/jama.280.7.614}, pmid = {9718052}, url = {https://doi.org/10.1001/jama.280.7.614} } @article{sanders2010-20068209, author = {Sanders, A. E. and Wang, C. and Katz, M. and Derby, C. A. and Barzilai, N. and Ozelius, L. and Lipton, R. B.}, title = {{Association of a functional polymorphism in the cholesteryl ester transfer protein (CETP) gene with memory decline and incidence of dementia}}, journal = {JAMA}, year = {2010}, doi = {10.1001/jama.2009.1988}, pmid = {20068209}, url = {https://doi.org/10.1001/jama.2009.1988} } @article{yaffe2011-21245181, author = {Yaffe, K. and Weston, A. and Graff-Radford, N. R. and Satterfield, S. and Simonsick, E. M. and Younkin, S. G. and Younkin, L. H. and Kuller, L. and others}, title = {{Association of plasma beta-amyloid level and cognitive reserve with subsequent cognitive decline}}, journal = {JAMA}, year = {2011}, doi = {10.1001/jama.2010.1995}, pmid = {21245181}, url = {https://doi.org/10.1001/jama.2010.1995} } @article{walter2001-11410097, author = {Walter, L. C. and Brand, R. J. and Counsell, SR. and Palmer, R. M. and Landefeld, C. S. and Fortinsky, R. H. and Covinsky, K. E.}, title = {{Development and validation of a prognostic index for 1-year mortality in older adults after hospitalization}}, journal = {JAMA}, year = {2001}, doi = {10.1001/jama.285.23.2987}, pmid = {11410097}, url = {https://doi.org/10.1001/jama.285.23.2987} } @article{mitchell2010-21045099, author = {Mitchell, S. L. and Miller, S. C. and Teno, J. M. and Kiely, D. K. and Davis, R. B. and Shaffer, M. L.}, title = {{Prediction of 6-month survival of nursing home residents with advanced dementia using ADEPT vs hospice eligibility guidelines}}, journal = {JAMA}, year = {2010}, doi = {10.1001/jama.2010.1572}, pmid = {21045099}, url = {https://doi.org/10.1001/jama.2010.1572} } @article{mitchell2003-12837714, author = {Mitchell, S. L. and Teno, J. M. and Roy, J. and Kabumoto, G. and Mor, V.}, title = {{Clinical and organizational factors associated with feeding tube use among nursing home residents with advanced cognitive impairment}}, journal = {JAMA}, year = {2003}, doi = {10.1001/jama.290.1.73}, pmid = {12837714}, url = {https://doi.org/10.1001/jama.290.1.73} } @article{tsou2020-33079159, author = {Tsou, A. Y. and Bulova, P. and Capone, G. and Chicoine, B. and Gelaro, B. and Harville, T. O. and Martin, B. A. and McGuire, D. E. and others}, title = {{Medical Care of Adults With Down Syndrome: A Clinical Guideline}}, journal = {JAMA}, year = {2020}, doi = {10.1001/jama.2020.17024}, pmid = {33079159}, url = {https://doi.org/10.1001/jama.2020.17024} } @article{arvanitakis2019-31638686, author = {Arvanitakis, Z. and Shah, R. C. and Bennett, D. A.}, title = {{Diagnosis and Management of Dementia: Review}}, journal = {JAMA}, year = {2019}, doi = {10.1001/jama.2019.4782}, pmid = {31638686}, url = {https://doi.org/10.1001/jama.2019.4782} } @article{connolly2014-24756517, author = {Connolly, B. S. and Lang, A. E.}, title = {{Pharmacological treatment of Parkinson disease: a review}}, journal = {JAMA}, year = {2014}, doi = {10.1001/jama.2014.3654}, pmid = {24756517}, url = {https://doi.org/10.1001/jama.2014.3654} } @article{naslund2000-10735393, author = {Näslund, J. and Haroutunian, V. and Mohs, R. and Davis, K. L. and Davies, P. and Greengard, P. and Buxbaum, J. D.}, title = {{Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline}}, journal = {JAMA}, year = {2000}, doi = {10.1001/jama.283.12.1571}, pmid = {10735393}, url = {https://doi.org/10.1001/jama.283.12.1571} } @article{lee2020-32062674, author = {Lee, R. Y. and Brumback, L. C. and Sathitratanacheewin, S. and Lober, W. B. and Modes, M. E. and Lynch, Y. T. and Ambrose, C. I. and Sibley, J. and others}, title = {{Association of Physician Orders for Life-Sustaining Treatment With ICU Admission Among Patients Hospitalized Near the End of Life}}, journal = {JAMA}, year = {2020}, doi = {10.1001/jama.2019.22523}, pmid = {32062674}, url = {https://doi.org/10.1001/jama.2019.22523} } @article{levine2015-26151265, author = {Levine, D. A. and Galecki, A. T. and Langa, K. M. and Unverzagt, F. W. and Kabeto, M. U. and Giordani, B. and Wadley, V. G.}, title = {{Trajectory of Cognitive Decline After Incident Stroke}}, journal = {JAMA}, year = {2015}, doi = {10.1001/jama.2015.6968}, pmid = {26151265}, url = {https://doi.org/10.1001/jama.2015.6968} } @article{lebars1997-f69c6c73, author = {Le Bars, Pierre L.}, title = {{A Placebo-Controlled, Double-blind, Randomized Trial of an Extract of Ginkgo Biloba for Dementia}}, journal = {JAMA}, year = {1997}, doi = {10.1001/jama.1997.03550160047037}, url = {https://doi.org/10.1001/jama.1997.03550160047037} } @article{langa2014-25514304, author = {Langa, K. M. and Levine, D. A.}, title = {{The diagnosis and management of mild cognitive impairment: a clinical review}}, journal = {JAMA}, year = {2014}, doi = {10.1001/jama.2014.13806}, pmid = {25514304}, url = {https://doi.org/10.1001/jama.2014.13806} } @article{lieb2009-20009056, author = {Lieb, W. and Beiser, A. S. and Vasan, R. S. and Tan, Z. S. and Au, R. and Harris, T. B. and Roubenoff, R. and Auerbach, S. and others}, title = {{Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging}}, journal = {JAMA}, year = {2009}, doi = {10.1001/jama.2009.1836}, pmid = {20009056}, url = {https://doi.org/10.1001/jama.2009.1836} } @article{gitlin2012-23168825, author = {Gitlin, L. N. and Kales, H. C. and Lyketsos, C. G.}, title = {{Nonpharmacologic management of behavioral symptoms in dementia}}, journal = {JAMA}, year = {2012}, doi = {10.1001/jama.2012.36918}, pmid = {23168825}, url = {https://doi.org/10.1001/jama.2012.36918} } @article{kok2017-28535241, author = {Kok, R. M. and Reynolds, C. F.}, title = {{Management of Depression in Older Adults: A Review}}, journal = {JAMA}, year = {2017}, doi = {10.1001/jama.2017.5706}, pmid = {28535241}, url = {https://doi.org/10.1001/jama.2017.5706} } @article{marcantonio2012-22669559, author = {Marcantonio, E. R.}, title = {{Postoperative delirium: a 76-year-old woman with delirium following surgery}}, journal = {JAMA}, year = {2012}, doi = {10.1001/jama.2012.6857}, pmid = {22669559}, url = {https://doi.org/10.1001/jama.2012.6857} } @article{ko2025-39680399, author = {Ko, D. and Chung, M. K. and Evans, P. T. and Benjamin, E. J. and Helm, R. H.}, title = {{Atrial Fibrillation: A Review}}, journal = {JAMA}, year = {2025}, doi = {10.1001/jama.2024.22451}, pmid = {39680399}, url = {https://doi.org/10.1001/jama.2024.22451} } @article{bevans2012-22274687, author = {Bevans, M. and Sternberg, E. M.}, title = {{Caregiving burden, stress, and health effects among family caregivers of adult cancer patients}}, journal = {JAMA}, year = {2012}, doi = {10.1001/jama.2012.29}, pmid = {22274687}, url = {https://doi.org/10.1001/jama.2012.29} } @article{white1996-8805729, author = {White, L. and Petrovitch, H. and Ross, G. W. and Masaki, K. H. and Abbott, R. D. and Teng, E. L. and Rodriguez, B. L. and Blanchette, P. L. and others}, title = {{Prevalence of dementia in older Japanese-American men in Hawaii: The Honolulu-Asia Aging Study}}, journal = {JAMA}, year = {1996}, doi = {10.1001/jama.1996.03540120033030}, pmid = {8805729}, url = {https://doi.org/10.1001/jama.1996.03540120033030} } @article{vichinsky2010-20460621, author = {Vichinsky, E. P. and Neumayr, L. D. and Gold, J. I. and Weiner, M. W. and Rule, R. R. and Truran, D. and Kasten, J. and Eggleston, B. and others}, title = {{Neuropsychological dysfunction and neuroimaging abnormalities in neurologically intact adults with sickle cell anemia}}, journal = {JAMA}, year = {2010}, doi = {10.1001/jama.2010.562}, pmid = {20460621}, url = {https://doi.org/10.1001/jama.2010.562} } @article{zandi2002-12413371, author = {Zandi, P. P. and Carlson, M. C. and Plassman, B. L. and Welsh-Bohmer, K. A. and Mayer, L. S. and Steffens, D. C. and Breitner, J. C. and {Cache County Memory Study Investigators}}, title = {{Hormone replacement therapy and incidence of Alzheimer disease in older women: the Cache County Study}}, journal = {JAMA}, year = {2002}, doi = {10.1001/jama.288.17.2123}, pmid = {12413371}, url = {https://doi.org/10.1001/jama.288.17.2123} } @article{crum1993-8479064, author = {Crum, Rosa M.}, title = {{Population-Based Norms for the Mini-Mental State Examination by Age and Educational Level}}, journal = {JAMA}, year = {1993}, doi = {10.1001/jama.1993.03500180078038}, pmid = {8479064}, url = {https://doi.org/10.1001/jama.1993.03500180078038} } @article{green2002-11790212, author = {Green, R. C. and Cupples, L. A. and Go, R. and Benke, K. S. and Edeki, T. and Griffith, P. A. and Williams, M. and Hipps, Y. and others}, title = {{Risk of dementia among white and African American relatives of patients with Alzheimer disease}}, journal = {JAMA}, year = {2002}, doi = {10.1001/jama.287.3.329}, pmid = {11790212}, url = {https://doi.org/10.1001/jama.287.3.329} } @article{hobson2002-11798367, author = {Hobson, D. E. and Lang, A. E. and Martin, W. R. and Razmy, A. and Rivest, J. and Fleming, J.}, title = {{Excessive daytime sleepiness and sudden-onset sleep in Parkinson disease: a survey by the Canadian Movement Disorders Group}}, journal = {JAMA}, year = {2002}, doi = {10.1001/jama.287.4.455}, pmid = {11798367}, url = {https://doi.org/10.1001/jama.287.4.455} } @article{schulz2004-15328328, author = {Schulz, R. and Belle, S. H. and Czaja, S. J. and McGinnis, K. A. and Stevens, A. and Zhang, S.}, title = {{Long-term care placement of dementia patients and caregiver health and well-being}}, journal = {JAMA}, year = {2004}, doi = {10.1001/jama.292.8.961}, pmid = {15328328}, url = {https://doi.org/10.1001/jama.292.8.961} } @article{schulz1999-10605972, author = {Schulz, Richard and Beach, Scott R.}, title = {{Caregiving as a risk factor for mortality: the Caregiver Health Effects Study}}, journal = {JAMA}, year = {1999}, doi = {10.1001/jama.282.23.2215}, pmid = {10605972}, url = {https://doi.org/10.1001/jama.282.23.2215} } @article{uhlmann1989-2926927, author = {Uhlmann, R. F. and Larson, E. B. and Rees, T. S. and Koepsell, T. D. and Duckert, L. G.}, title = {{Relationship of hearing impairment to dementia and cognitive dysfunction in older adults}}, journal = {JAMA}, year = {1989}, doi = {10.1001/jama.1989.03420130084028}, pmid = {2926927}, url = {https://doi.org/10.1001/jama.1989.03420130084028} } @article{ray1989-2573741, author = {Ray, W. A. and Griffin, M. R. and Downey, W.}, title = {{Benzodiazepines of long and short elimination half-life and the risk of hip fracture}}, journal = {JAMA}, year = {1989}, doi = {10.1001/jama.1989.03430230088031}, pmid = {2573741}, url = {https://doi.org/10.1001/jama.1989.03430230088031} } @article{maust2021-33687462, author = {Maust, D. T. and Strominger, J. and Kim, H. M. and Langa, K. M. and Bynum, J. P. W. and Chang, C. H. and Kales, H. C. and Zivin, K. and others}, title = {{Prevalence of Central Nervous System-Active Polypharmacy Among Older Adults With Dementia in the US}}, journal = {JAMA}, year = {2021}, doi = {10.1001/jama.2021.1195}, pmid = {33687462}, url = {https://doi.org/10.1001/jama.2021.1195} } @article{brown2026-42437499, author = {Brown, C. A. and Robinson, J. L. and Das, SR. and McGrew, E. and Suh, E. and Van Deerlin, V. M. and Irwin, D. J. and Nasrallah, I. M. and others}, title = {{Clinicopathologic Evaluation of Amyloid Clearance in Alzheimer Disease}}, journal = {JAMA}, year = {2026}, doi = {10.1001/jama.2026.13058}, pmid = {42437499}, url = {https://doi.org/10.1001/jama.2026.13058} } @article{morris2002-12076219, author = {Morris, M. C. and Evans, D. A. and Bienias, J. L. and Tangney, C. C. and Bennett, D. A. and Aggarwal, N. and Wilson, R. S. and Scherr, P. A.}, title = {{Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study}}, journal = {JAMA}, year = {2002}, doi = {10.1001/jama.287.24.3230}, pmid = {12076219}, url = {https://doi.org/10.1001/jama.287.24.3230} } @article{pericakvance1997-9333264, author = {Pericak-Vance, M. A. and Bass, M. P. and Yamaoka, L. H. and Gaskell, P. C. and Scott, W. K. and Terwedow, H. A. and Menold, M. M. and Conneally, P. M. and others}, title = {{Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12}}, journal = {JAMA}, year = {1997}, doi = {10.1001/jama.1997.03550150041033}, pmid = {9333264}, url = {https://doi.org/10.1001/jama.1997.03550150041033} } @article{study2017-29234814, author = {{US Preventive Services Task Force} and Grossman, D. C. and Curry, S. J. and Owens, D. K. and Barry, M. J. and Davidson, K. W. and Doubeni, C. A. and Epling, J. W. and others}, title = {{Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Women: US Preventive Services Task Force Recommendation Statement}}, journal = {JAMA}, year = {2017}, doi = {10.1001/jama.2017.18261}, pmid = {29234814}, url = {https://doi.org/10.1001/jama.2017.18261} } @article{small1997-9343469, author = {Small, G. W. and Rabins, P. V. and Barry, P. P. and Buckholtz, N. S. and DeKosky, S. T. and Ferris, S. H. and Finkel, S. I. and Gwyther, L. P. and others}, title = {{Diagnosis and treatment of Alzheimer disease and related disorders. Consensus statement of the American Association for Geriatric Psychiatry, the Alzheimer's Association, and the American Geriatrics Society}}, journal = {JAMA}, year = {1997}, doi = {10.1001/jama.1997.03550160083043}, pmid = {9343469}, url = {https://doi.org/10.1001/jama.1997.03550160083043} } @article{welch2011-21406648, author = {Welch, H. Gilbert}, title = {{Geographic Variation in Diagnosis Frequency and Risk of Death Among Medicare Beneficiaries}}, journal = {JAMA}, year = {2011}, doi = {10.1001/jama.2011.307}, pmid = {21406648}, url = {https://doi.org/10.1001/jama.2011.307} } @article{stallard2025-40072416, author = {Stallard, P. J. Eric and Ukraintseva, Svetlana V. and Doraiswamy, Pudugramam Murali}, title = {{Changing Story of the Dementia Epidemic}}, journal = {JAMA}, year = {2025}, doi = {10.1001/jama.2025.1897}, pmid = {40072416}, url = {https://doi.org/10.1001/jama.2025.1897} } @article{evans1989-5d39a55d, author = {Evans, Denis A.}, title = {{Prevalence of Alzheimer's Disease in a Community Population of Older Persons}}, journal = {JAMA}, year = {1989}, doi = {10.1001/jama.1989.03430180093036}, url = {https://doi.org/10.1001/jama.1989.03430180093036} } @article{buchner1987-3820464, author = {Buchner, D. M. and Larson, E. B.}, title = {{Falls and fractures in patients with Alzheimer-type dementia}}, journal = {JAMA}, year = {1987}, doi = {10.1001/jama.1987.03390110068028}, pmid = {3820464}, url = {https://doi.org/10.1001/jama.1987.03390110068028} } @article{davis1999-10217056, author = {Davis, K. L. and Mohs, R. C. and Marin, D. and Purohit, D. P. and Perl, D. P. and Lantz, M. and Austin, G. and Haroutunian, V.}, title = {{Cholinergic markers in elderly patients with early signs of Alzheimer disease}}, journal = {JAMA}, year = {1999}, doi = {10.1001/jama.281.15.1401}, pmid = {10217056}, url = {https://doi.org/10.1001/jama.281.15.1401} } @article{katz1963-14044222, author = {Katz, Sidney and A B, F. O. R. D. and MOSKOWITZ, R W and JACKSON, B A and JAFFE, M W}, title = {{STUDIES OF ILLNESS IN THE AGED. THE INDEX OF ADL: A STANDARDIZED MEASURE OF BIOLOGICAL AND PSYCHOSOCIAL FUNCTION}}, journal = {JAMA}, year = {1963}, doi = {10.1001/jama.1963.03060120024016}, pmid = {14044222}, url = {https://doi.org/10.1001/jama.1963.03060120024016} } @article{watkins1994-8139084, author = {Watkins, Paul Brent}, title = {{Hepatotoxic Effects of Tacrine Administration in Patients With Alzheimer's Disease}}, journal = {JAMA}, year = {1994}, doi = {10.1001/jama.1994.03510370044030}, pmid = {8139084}, url = {https://doi.org/10.1001/jama.1994.03510370044030} } @article{evans1989-2feff34f, author = {Evans, Denis A.}, title = {{Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported}}, journal = {JAMA}, year = {1989}, doi = {10.1001/jama.262.18.2551}, url = {https://doi.org/10.1001/jama.262.18.2551} } @article{bos2007-18159057, author = {Bos, M. J. and van Rijn, M. J. and Witteman, J. C. and Hofman, A. and Koudstaal, P. J. and Breteler, M. M.}, title = {{Incidence and prognosis of transient neurological attacks}}, journal = {JAMA}, year = {2007}, doi = {10.1001/jama.298.24.2877}, pmid = {18159057}, url = {https://doi.org/10.1001/jama.298.24.2877} } @article{mez2017-28742910, author = {Mez, J. and Daneshvar, D. H. and Kiernan, P. T. and Abdolmohammadi, B. and Alvarez, V. E. and Huber, B. R. and Alosco, M. L. and Solomon, T. M. and others}, title = {{Clinicopathological Evaluation of Chronic Traumatic Encephalopathy in Players of American Football}}, journal = {JAMA}, year = {2017}, doi = {10.1001/jama.2017.8334}, pmid = {28742910}, url = {https://doi.org/10.1001/jama.2017.8334} } @article{lopera1997-9052708, author = {Lopera, F. and Ardilla, A. and Martínez, A. and Madrigal, L. and Arango-Viana, J. C. and Lemere, C. A. and Arango-Lasprilla, J. C. and Hincapíe, L. and others}, title = {{Clinical features of early-onset Alzheimer disease in a large kindred with an E280A presenilin-1 mutation}}, journal = {JAMA}, year = {1997}, doi = {10.1001/jama.1997.03540340027028}, pmid = {9052708}, url = {https://doi.org/10.1001/jama.1997.03540340027028} } @article{tatsioni2007-18056905, author = {Tatsioni, A. and Bonitsis, N. G. and Ioannidis, J. P.}, title = {{Persistence of contradicted claims in the literature}}, journal = {JAMA}, year = {2007}, doi = {10.1001/jama.298.21.2517}, pmid = {18056905}, url = {https://doi.org/10.1001/jama.298.21.2517} } @article{francis1990-2299782, author = {Francis, J. and Martin, D. and Kapoor, W. N.}, title = {{A prospective study of delirium in hospitalized elderly}}, journal = {JAMA}, year = {1990}, doi = {10.1001/jama.1990.03440080075027}, pmid = {2299782}, url = {https://doi.org/10.1001/jama.1990.03440080075027} } @article{sunderland2003-12709467, author = {Sunderland, Trey and Linker, Gary and Mirza, Nadeem and Putnam, Karen T. and Friedman, David L. and Kimmel, Lida H. and Bergeson, Judy and Manetti, Guy J. and Zimmermann, Matthew and Tang, Brian and Bartko, John J. and Cohen, Robert M.}, title = {{Decreased β-Amyloid1-42and Increased Tau Levels in Cerebrospinal Fluid of Patients With Alzheimer Disease}}, journal = {JAMA}, year = {2003}, doi = {10.1001/jama.289.16.2094}, pmid = {12709467}, url = {https://doi.org/10.1001/jama.289.16.2094} } @article{jordan1997-9214529, author = {Jordan, B. D. and Relkin, N. R. and Ravdin, L. D. and Jacobs, A. R. and Bennett, A. and Gandy, S.}, title = {{Apolipoprotein E epsilon4 associated with chronic traumatic brain injury in boxing}}, journal = {JAMA}, year = {1997}, doi = {10.1001/jama.1997.03550020068040}, pmid = {9214529}, url = {https://doi.org/10.1001/jama.1997.03550020068040} } @article{lendon1997-9052714, author = {Lendon, C. L. and Ashall, F. and Goate, A. M.}, title = {{Exploring the etiology of Alzheimer disease using molecular genetics}}, journal = {JAMA}, year = {1997}, doi = {10.1001/jama.1997.03540340059034}, pmid = {9052714}, url = {https://doi.org/10.1001/jama.1997.03540340059034} } @article{volicer1986-3761520, author = {Volicer, L. and Rheaume, Y. and Brown, J. and Fabiszewski, K. and Brady, R.}, title = {{Hospice approach to the treatment of patients with advanced dementia of the Alzheimer type}}, journal = {JAMA}, year = {1986}, doi = {10.1001/jama.1986.03380160068022}, pmid = {3761520}, url = {https://doi.org/10.1001/jama.1986.03380160068022} } @article{fabiszewski1990-1693407, author = {Fabiszewski, K. J. and Volicer, B. and Volicer, L.}, title = {{Effect of antibiotic treatment on outcome of fevers in institutionalized Alzheimer patients}}, journal = {JAMA}, year = {1990}, doi = {10.1001/jama.1990.03440230064034}, pmid = {1693407}, url = {https://doi.org/10.1001/jama.1990.03440230064034} } @article{rabins1982-7087127, author = {Rabins, Peter V.}, title = {{The Impact of Dementia on the Family}}, journal = {JAMA}, year = {1982}, doi = {10.1001/jama.1982.03330030039022}, pmid = {7087127}, url = {https://doi.org/10.1001/jama.1982.03330030039022} } @article{post1997-9052715, author = {Post, S. G. and Whitehouse, P. J. and Binstock, R. H. and Bird, T. D. and Eckert, S. K. and Farrer, L. A. and Fleck, L. M. and Gaines, A. D. and others}, title = {{The clinical introduction of genetic testing for Alzheimer disease. An ethical perspective}}, journal = {JAMA}, year = {1997}, doi = {10.1001/jama.277.10.832}, pmid = {9052715}, url = {https://doi.org/10.1001/jama.277.10.832} } @article{snowdon1997-b8bd5c53, author = {Snowdon, David A.}, title = {{Brain Infarction and the Clinical Expression of Alzheimer Disease-Reply}}, journal = {JAMA}, year = {1997}, doi = {10.1001/jama.1997.03550020046024}, url = {https://doi.org/10.1001/jama.1997.03550020046024} } @article{lynn2001-11180736, author = {Lynn, J.}, title = {{Perspectives on care at the close of life. Serving patients who may die soon and their families: the role of hospice and other services}}, journal = {JAMA}, year = {2001}, doi = {10.1001/jama.285.7.925}, pmid = {11180736}, url = {https://doi.org/10.1001/jama.285.7.925} } @article{cohen2003-12709469, author = {Cohen, L. M. and Germain, M. J. and Poppel, D. M.}, title = {{Practical considerations in dialysis withdrawal: "to have that option is a blessing"}}, journal = {JAMA}, year = {2003}, doi = {10.1001/jama.289.16.2113}, pmid = {12709469}, url = {https://doi.org/10.1001/jama.289.16.2113} } @article{mitchell2007-17986683, author = {Mitchell, S. L.}, title = {{A 93-year-old man with advanced dementia and eating problems}}, journal = {JAMA}, year = {2007}, doi = {10.1001/jama.298.17.jrr70001}, pmid = {17986683}, url = {https://doi.org/10.1001/jama.298.17.jrr70001} } @article{schenck1987-3820495, author = {Schenck, C. H. and Bundlie, SR. and Patterson, A. L. and Mahowald, M. W.}, title = {{Rapid eye movement sleep behavior disorder. A treatable parasomnia affecting older adults}}, journal = {JAMA}, year = {1987}, doi = {10.1001/jama.1987.03390130104038}, pmid = {3820495}, url = {https://doi.org/10.1001/jama.1987.03390130104038} } @article{dieleman2020-32125402, author = {Dieleman, J. L. and Cao, J. and Chapin, A. and Chen, C. and Li, Z. and Liu, A. and Horst, C. and Kaldjian, A. and others}, title = {{US Health Care Spending by Payer and Health Condition, 1996-2016}}, journal = {JAMA}, year = {2020}, doi = {10.1001/jama.2020.0734}, pmid = {32125402}, url = {https://doi.org/10.1001/jama.2020.0734} } @article{anderson2022-43c114a8, author = {Anderson, Kelly E. and Darden, Michael and Jain, Amit}, title = {{Improving Prior Authorization in Medicare Advantage}}, journal = {JAMA}, year = {2022}, doi = {10.1001/jama.2022.17732}, url = {https://doi.org/10.1001/jama.2022.17732} } @article{anderson2021-34499725, author = {Anderson, Timothy S and Ayanian, John Z and Souza, Jeffrey and Landon, Bruce E}, title = {{Representativeness of Participants Eligible to Be Enrolled in Clinical Trials of Aducanumab for Alzheimer Disease Compared With Medicare Beneficiaries With Alzheimer Disease and Mild Cognitive Impairment}}, journal = {JAMA}, year = {2021}, doi = {10.1001/jama.2021.15286}, pmid = {34499725}, url = {https://doi.org/10.1001/jama.2021.15286} } @article{pablosmendez1998-9438743, author = {Pablos-Méndez, A. and Barr, R. G. and Shea, S.}, title = {{Run-in periods in randomized trials: implications for the application of results in clinical practice}}, journal = {JAMA}, year = {1998}, doi = {10.1001/jama.279.3.222}, pmid = {9438743}, url = {https://doi.org/10.1001/jama.279.3.222} } @article{rathi2025-2086bc4b, author = {Rathi, Vinay K. and Dhruva, Sanket S. and Ross, Joseph S.}, title = {{Expanding Prior Authorization in Traditional Medicare—The WISeR Model}}, journal = {JAMA}, year = {2025}, doi = {10.1001/jama.2025.16326}, url = {https://doi.org/10.1001/jama.2025.16326} } @article{armstrong2020-32044947, author = {Armstrong, M. J. and Okun, M. S.}, title = {{Diagnosis and Treatment of Parkinson Disease: A Review}}, journal = {JAMA}, year = {2020}, doi = {10.1001/jama.2019.22360}, pmid = {32044947}, url = {https://doi.org/10.1001/jama.2019.22360} } @article{rubin2025-40844810, author = {Rubin, Rita}, title = {{Treating Alzheimer Disease With Antiamyloid Therapies—The Real-World Experience Grows}}, journal = {JAMA}, year = {2025}, doi = {10.1001/jama.2025.14180}, pmid = {40844810}, url = {https://doi.org/10.1001/jama.2025.14180} } @article{fitten1995-7715061, author = {Fitten, L. J. and Perryman, K. M. and Wilkinson, C. J. and Little, R. J. and Burns, M. M. and Pachana, N. and Mervis, JR. and Malmgren, R. and others}, title = {{Alzheimer and vascular dementias and driving. A prospective road and laboratory study}}, journal = {JAMA}, year = {1995}, doi = {10.1001/jama.1995.03520410054026}, pmid = {7715061}, url = {https://doi.org/10.1001/jama.1995.03520410054026} } @article{carr2010-20424254, author = {Carr, D. B. and Ott, B. R.}, title = {{The older adult driver with cognitive impairment: "It's a very frustrating life"}}, journal = {JAMA}, year = {2010}, doi = {10.1001/jama.2010.481}, pmid = {20424254}, url = {https://doi.org/10.1001/jama.2010.481} } @article{mccue1995-7897788, author = {McCue, J. D.}, title = {{The naturalness of dying}}, journal = {JAMA}, year = {1995}, doi = {10.1001/jama.1995.03520370081041}, pmid = {7897788}, url = {https://doi.org/10.1001/jama.1995.03520370081041} } @article{teno2010-20145231, author = {Teno, J. M. and Mitchell, S. L. and Gozalo, P. L. and Dosa, D. and Hsu, A. and Intrator, O. and Mor, V.}, title = {{Hospital characteristics associated with feeding tube placement in nursing home residents with advanced cognitive impairment}}, journal = {JAMA}, year = {2010}, doi = {10.1001/jama.2010.79}, pmid = {20145231}, url = {https://doi.org/10.1001/jama.2010.79} } @article{schiffman1997-9343468, author = {Schiffman, S. S.}, title = {{Taste and smell losses in normal aging and disease}}, journal = {JAMA}, year = {1997}, doi = {10.1001/jama.1997.03550160077042}, pmid = {9343468}, url = {https://doi.org/10.1001/jama.1997.03550160077042} } @article{schneider1990-2109105, author = {Schneider, E. L. and Guralnik, J. M.}, title = {{The aging of America. Impact on health care costs}}, journal = {JAMA}, year = {1990}, doi = {10.1001/jama.1990.03440170057036}, pmid = {2109105}, url = {https://doi.org/10.1001/jama.1990.03440170057036} } @article{sehgal1992-1489360, author = {Sehgal, A. and Galbraith, A. and Chesney, M. and Schoenfeld, P. and Charles, G. and Lo, B.}, title = {{How strictly do dialysis patients want their advance directives followed?}}, journal = {JAMA}, year = {1992}, doi = {10.1001/jama.1992.03480010067026}, pmid = {1489360}, url = {https://doi.org/10.1001/jama.1992.03480010067026} } @article{roman1987-3625988, author = {Román, G. C.}, title = {{Senile dementia of the Binswanger type. A vascular form of dementia in the elderly}}, journal = {JAMA}, year = {1987}, doi = {10.1001/jama.1987.03400130096040}, pmid = {3625988}, url = {https://doi.org/10.1001/jama.1987.03400130096040} } @article{cahan2024-995f950e, author = {Cahan, Eli}, title = {{Medicare Advantage Has Become Notorious for Prior Authorization—CMS and Lawmakers Are Taking Action}}, journal = {JAMA}, year = {2024}, doi = {10.1001/jama.2024.13383}, url = {https://doi.org/10.1001/jama.2024.13383} }