% alzhub.org library filter % Source: https://alzhub.org/research?institution=I79576946 % 500 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{kunkle2019-30820047, author = {Kunkle, B. W. and Grenier-Boley, B. and Sims, R. and Bis, J. C. and Damotte, V. and Naj, A. C. and Boland, A. and Vronskaya, M. and others}, title = {{Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing}}, journal = {Nature genetics}, year = {2019}, doi = {10.1038/s41588-019-0358-2}, pmid = {30820047}, url = {https://doi.org/10.1038/s41588-019-0358-2} } @article{jansen2015-25988462, author = {Jansen, W. J. and Ossenkoppele, R. and Knol, D. L. and Tijms, B. M. and Scheltens, P. and Verhey, F. R. and Visser, P. J. and {Amyloid Biomarker Study Group} and others}, title = {{Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis}}, journal = {JAMA}, year = {2015}, doi = {10.1001/jama.2015.4668}, pmid = {25988462}, url = {https://doi.org/10.1001/jama.2015.4668} } @article{ossenkoppele2015-25988463, author = {Ossenkoppele, R. and Jansen, W. J. and Rabinovici, G. D. and Knol, D. L. and van der Flier, W. M. and van Berckel, B. N. and Scheltens, P. and Visser, P. J. and others}, title = {{Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis}}, journal = {JAMA}, year = {2015}, doi = {10.1001/jama.2015.4669}, pmid = {25988463}, url = {https://doi.org/10.1001/jama.2015.4669} } @article{naj2011-21460841, author = {Naj, A. C. and Jun, G. and Beecham, G. W. and Wang, L. S. and Vardarajan, B. N. and Buros, J. and Gallins, P. J. and Buxbaum, J. D. and others}, title = {{Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease}}, journal = {Nature genetics}, year = {2011}, doi = {10.1038/ng.801}, pmid = {21460841}, url = {https://doi.org/10.1038/ng.801} } @article{porsteinsson2014-24549548, author = {Porsteinsson, A. P. and Drye, L. T. and Pollock, B. G. and Devanand, D. P. and Frangakis, C. and Ismail, Z. and Marano, C. and Meinert, C. L. and others}, title = {{Effect of citalopram on agitation in Alzheimer disease: the CitAD randomized clinical trial}}, journal = {JAMA}, year = {2014}, doi = {10.1001/jama.2014.93}, pmid = {24549548}, url = {https://doi.org/10.1001/jama.2014.93} } @article{sims2017-28714976, author = {Sims, R. and van der Lee, S. J. and Naj, A. C. and Bellenguez, C. and Badarinarayan, N. and Jakobsdottir, J. and Kunkle, B. W. and Boland, A. and others}, title = {{Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease}}, journal = {Nature genetics}, year = {2017}, doi = {10.1038/ng.3916}, pmid = {28714976}, url = {https://doi.org/10.1038/ng.3916} } @article{jun2016-25778476, author = {Jun, G. and Ibrahim-Verbaas, C. A. and Vronskaya, M. and Lambert, J. C. and Chung, J. and Naj, A. C. and Kunkle, B. W. and Wang, L. S. and others}, title = {{A novel Alzheimer disease locus located near the gene encoding tau protein}}, journal = {Molecular psychiatry}, year = {2016}, doi = {10.1038/mp.2015.23}, pmid = {25778476}, url = {https://doi.org/10.1038/mp.2015.23} } @article{dysken2014-24381967, author = {Dysken, M. W. and Sano, M. and Asthana, S. and Vertrees, J. E. and Pallaki, M. and Llorente, M. and Love, S. and Schellenberg, G. D. and others}, title = {{Effect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trial}}, journal = {JAMA}, year = {2014}, doi = {10.1001/jama.2013.282834}, pmid = {24381967}, url = {https://doi.org/10.1001/jama.2013.282834} } @article{reitz2013-23571587, author = {Reitz, C. and Jun, G. and Naj, A. and Rajbhandary, R. and Vardarajan, B. N. and Wang, L. S. and Valladares, O. and Lin, C. F. and others}, title = {{Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans}}, journal = {JAMA}, year = {2013}, doi = {10.1001/jama.2013.2973}, pmid = {23571587}, url = {https://doi.org/10.1001/jama.2013.2973} } @article{kunkle2021-33074286, author = {Kunkle, B. W. and Schmidt, M. and Klein, H. U. and Naj, A. C. and Hamilton-Nelson, K. L. and Larson, E. B. and Evans, D. A. and De Jager, P. L. and others}, title = {{Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis}}, journal = {JAMA neurology}, year = {2021}, doi = {10.1001/jamaneurol.2020.3536}, pmid = {33074286}, url = {https://doi.org/10.1001/jamaneurol.2020.3536} } @article{ferrari2014-24943344, author = {Ferrari, R. and Hernandez, D. G. and Nalls, M. A. and Rohrer, J. D. and Ramasamy, A. and Kwok, J. B. and Dobson-Stone, C. and Brooks, W. S. and others}, title = {{Frontotemporal dementia and its subtypes: a genome-wide association study}}, journal = {The Lancet. Neurology}, year = {2014}, doi = {10.1016/s1474-4422(14)70065-1}, pmid = {24943344}, url = {https://doi.org/10.1016/s1474-4422(14)70065-1} } @article{study2019-30688979, author = {{SPRINT MIND Investigators for the SPRINT Research Group} and Williamson, J. D. and Pajewski, N. M. and Auchus, A. P. and Bryan, R. N. and Chelune, G. and Cheung, A. K. and Cleveland, M. L. and others}, title = {{Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial}}, journal = {JAMA}, year = {2019}, doi = {10.1001/jama.2018.21442}, pmid = {30688979}, url = {https://doi.org/10.1001/jama.2018.21442} } @article{gray2015-25621434, author = {Gray, S. L. and Anderson, M. L. and Dublin, S. and Hanlon, J. T. and Hubbard, R. and Walker, R. and Yu, O. and Crane, P. K. and others}, title = {{Cumulative use of strong anticholinergics and incident dementia: a prospective cohort study}}, journal = {JAMA internal medicine}, year = {2015}, doi = {10.1001/jamainternmed.2014.7663}, pmid = {25621434}, url = {https://doi.org/10.1001/jamainternmed.2014.7663} } @article{rajabli2025-40676597, author = {Rajabli, F. and Benchek, P. and Tosto, G. and Kushch, N. and Sha, J. and Bazemore, K. and Zhu, C. and Lee, W. P. and others}, title = {{Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease}}, journal = {Genome biology}, year = {2025}, doi = {10.1186/s13059-025-03564-z}, pmid = {40676597}, url = {https://doi.org/10.1186/s13059-025-03564-z} } @article{mattsson2019-31009028, author = {Mattsson, N. and Cullen, N. C. and Andreasson, U. and Zetterberg, H. and Blennow, K.}, title = {{Association Between Longitudinal Plasma Neurofilament Light and Neurodegeneration in Patients With Alzheimer Disease}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2019.0765}, pmid = {31009028}, url = {https://doi.org/10.1001/jamaneurol.2019.0765} } @article{bergeron2018-30255971, author = {Bergeron, D. and Gorno-Tempini, M. L. and Rabinovici, G. D. and Santos-Santos, M. A. and Seeley, W. and Miller, B. L. and Pijnenburg, Y. and Keulen, M. A. and others}, title = {{Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia}}, journal = {Annals of neurology}, year = {2018}, doi = {10.1002/ana.25333}, pmid = {30255971}, url = {https://doi.org/10.1002/ana.25333} } @article{karikari2021-33106600, author = {Karikari, T. K. and Benedet, A. L. and Ashton, N. J. and Lantero Rodriguez, J. and Snellman, A. and Suárez-Calvet, M. and Saha-Chaudhuri, P. and Lussier, F. and others}, title = {{Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer's Disease Neuroimaging Initiative}}, journal = {Molecular psychiatry}, year = {2021}, doi = {10.1038/s41380-020-00923-z}, pmid = {33106600}, url = {https://doi.org/10.1038/s41380-020-00923-z} } @article{xu2025-40067298, author = {Xu, X. and Kwon, J. and Yan, R. and Apio, C. and Song, S. and Heo, G. and Yang, Q. and Timsina, J. and others}, title = {{Sex Differences in Apolipoprotein E and Alzheimer Disease Pathology Across Ancestries}}, journal = {JAMA network open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.0562}, pmid = {40067298}, url = {https://doi.org/10.1001/jamanetworkopen.2025.0562} } @article{lill2015-25936935, author = {Lill, C. M. and Rengmark, A. and Pihlstrøm, L. and Fogh, I. and Shatunov, A. and Sleiman, P. M. and Wang, L. S. and Liu, T. and others}, title = {{The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2015}, doi = {10.1016/j.jalz.2014.12.009}, pmid = {25936935}, url = {https://doi.org/10.1016/j.jalz.2014.12.009} } @article{pottier2025-40280976, author = {Pottier, Cyril P. and Küçükali, Fahri and Baker, Matt C. and Batzler, Anthony and Jenkins, Gregory D. and van Blitterswijk, Marka and Vicente, Cristina T. and De Coster, Wouter and others}, title = {{Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing}}, journal = {Nature Communications}, year = {2025}, doi = {10.1038/s41467-025-59216-0}, pmid = {40280976}, url = {https://doi.org/10.1038/s41467-025-59216-0} } @article{neu2017-28846757, author = {Neu, S. C. and Pa, J. and Kukull, W. and Beekly, D. and Kuzma, A. and Gangadharan, P. and Wang, L. S. and Romero, K. and others}, title = {{Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis}}, journal = {JAMA neurology}, year = {2017}, doi = {10.1001/jamaneurol.2017.2188}, pmid = {28846757}, url = {https://doi.org/10.1001/jamaneurol.2017.2188} } @article{grill2020-32777010, author = {Grill, J. D. and Raman, R. and Ernstrom, K. and Sultzer, D. L. and Burns, J. M. and Donohue, M. C. and Johnson, K. A. and Aisen, P. S. and others}, title = {{Short-term Psychological Outcomes of Disclosing Amyloid Imaging Results to Research Participants Who Do Not Have Cognitive Impairment}}, journal = {JAMA neurology}, year = {2020}, doi = {10.1001/jamaneurol.2020.2734}, pmid = {32777010}, url = {https://doi.org/10.1001/jamaneurol.2020.2734} } @article{mattsson2016-27694257, author = {Mattsson, N. and Zetterberg, H. and Janelidze, S. and Insel, P. S. and Andreasson, U. and Stomrud, E. and Palmqvist, S. and Baker, D. and others}, title = {{Plasma tau in Alzheimer disease}}, journal = {Neurology}, year = {2016}, doi = {10.1212/wnl.0000000000003246}, pmid = {27694257}, url = {https://doi.org/10.1212/wnl.0000000000003246} } @article{rojas2021-33827960, author = {Rojas, J. C. and Wang, P. and Staffaroni, A. M. and Heller, C. and Cobigo, Y. and Wolf, A. and Goh, S. M. and Ljubenkov, P. A. and others}, title = {{Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration}}, journal = {Neurology}, year = {2021}, doi = {10.1212/wnl.0000000000011848}, pmid = {33827960}, url = {https://doi.org/10.1212/wnl.0000000000011848} } @article{besser2018-30376508, author = {Besser, L. and Kukull, W. and Knopman, D. S. and Chui, H. and Galasko, D. and Weintraub, S. and Jicha, G. and Carlsson, C. and others}, title = {{Version 3 of the National Alzheimer's Coordinating Center's Uniform Data Set}}, journal = {Alzheimer disease and associated disorders}, year = {2018}, doi = {10.1097/wad.0000000000000279}, pmid = {30376508}, url = {https://doi.org/10.1097/wad.0000000000000279} } @article{leuzy2022-34928318, author = {Leuzy, A. and Smith, R. and Cullen, N. C. and Strandberg, O. and Vogel, J. W. and Binette, A. P. and Borroni, E. and Janelidze, S. and others}, title = {{Biomarker-Based Prediction of Longitudinal Tau Positron Emission Tomography in Alzheimer Disease}}, journal = {JAMA neurology}, year = {2022}, doi = {10.1001/jamaneurol.2021.4654}, pmid = {34928318}, url = {https://doi.org/10.1001/jamaneurol.2021.4654} } @article{naj2014-25199842, author = {Naj, A. C. and Jun, G. and Reitz, C. and Kunkle, B. W. and Perry, W. and Park, Y. S. and Beecham, G. W. and Rajbhandary, R. A. and others}, title = {{Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study}}, journal = {JAMA neurology}, year = {2014}, doi = {10.1001/jamaneurol.2014.1491}, pmid = {25199842}, url = {https://doi.org/10.1001/jamaneurol.2014.1491} } @article{koton2022-35072712, author = {Koton, S. and Pike, JR. and Johansen, M. and Knopman, D. S. and Lakshminarayan, K. and Mosley, T. and Patole, S. and Rosamond, W. D. and others}, title = {{Association of Ischemic Stroke Incidence, Severity, and Recurrence With Dementia in the Atherosclerosis Risk in Communities Cohort Study}}, journal = {JAMA neurology}, year = {2022}, doi = {10.1001/jamaneurol.2021.5080}, pmid = {35072712}, url = {https://doi.org/10.1001/jamaneurol.2021.5080} } @article{nelson2014-24770881, author = {Nelson, P. T. and Estus, S. and Abner, E. L. and Parikh, I. and Malik, M. and Neltner, J. H. and Ighodaro, E. and Wang, W. X. and others}, title = {{ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology}}, journal = {Acta neuropathologica}, year = {2014}, doi = {10.1007/s00401-014-1282-2}, pmid = {24770881}, url = {https://doi.org/10.1007/s00401-014-1282-2} } @article{coe2026-41669119, author = {Coe, Norma B. and Miller, Katherine E. M. and Sun, Chuxuan and Taggert, Elizabeth and Gross, Alden L. and Jones, Richard Norman and Felix, Cynthia and Albert, Marilyn S. and others}, title = {{Impact of cognitive training on claims‐based diagnosed dementia over 20 years: evidence from the ACTIVE study}}, journal = {Alzheimer s \& Dementia Translational Research \& Clinical Interventions}, year = {2026}, doi = {10.1002/trc2.70197}, pmid = {41669119}, url = {https://doi.org/10.1002/trc2.70197} } @article{hohman2018-29801024, author = {Hohman, T. J. and Dumitrescu, L. and Barnes, L. L. and Thambisetty, M. and Beecham, G. and Kunkle, B. and Gifford, K. A. and Bush, W. S. and others}, title = {{Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau}}, journal = {JAMA neurology}, year = {2018}, doi = {10.1001/jamaneurol.2018.0821}, pmid = {29801024}, url = {https://doi.org/10.1001/jamaneurol.2018.0821} } @article{rosenberg2010-20087081, author = {Rosenberg, P. B. and Drye, L. T. and Martin, B. K. and Frangakis, C. and Mintzer, J. E. and Weintraub, D. and Porsteinsson, A. P. and Schneider, L. S. and others}, title = {{Sertraline for the treatment of depression in Alzheimer disease}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2010}, doi = {10.1097/jgp.0b013e3181c796eb}, pmid = {20087081}, url = {https://doi.org/10.1097/jgp.0b013e3181c796eb} } @article{nasrallah2021-33683313, author = {Nasrallah, I. M. and Gaussoin, S. A. and Pomponio, R. and Dolui, S. and Erus, G. and Wright, C. B. and Launer, L. J. and Detre, J. A. and others}, title = {{Association of Intensive vs Standard Blood Pressure Control With Magnetic Resonance Imaging Biomarkers of Alzheimer Disease: Secondary Analysis of the SPRINT MIND Randomized Trial}}, journal = {JAMA neurology}, year = {2021}, doi = {10.1001/jamaneurol.2021.0178}, pmid = {33683313}, url = {https://doi.org/10.1001/jamaneurol.2021.0178} } @article{nalls2013-23588557, author = {Nalls, M. A. and Duran, R. and Lopez, G. and Kurzawa-Akanbi, M. and McKeith, I. G. and Chinnery, P. F. and Morris, C. M. and Theuns, J. and others}, title = {{A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies}}, journal = {JAMA neurology}, year = {2013}, doi = {10.1001/jamaneurol.2013.1925}, pmid = {23588557}, url = {https://doi.org/10.1001/jamaneurol.2013.1925} } @article{seppi2011-22021174, author = {Seppi, K. and Weintraub, D. and Coelho, M. and Perez-Lloret, S. and Fox, S. H. and Katzenschlager, R. and Hametner, E. M. and Poewe, W. and others}, title = {{The Movement Disorder Society Evidence-Based Medicine Review Update: Treatments for the non-motor symptoms of Parkinson's disease}}, journal = {Movement disorders : official journal of the Movement Disorder Society}, year = {2011}, doi = {10.1002/mds.23884}, pmid = {22021174}, url = {https://doi.org/10.1002/mds.23884} } @article{taylor2020-31519472, author = {Taylor, J. P. and McKeith, I. G. and Burn, D. J. and Boeve, B. F. and Weintraub, D. and Bamford, C. and Allan, L. M. and Thomas, A. J. and others}, title = {{New evidence on the management of Lewy body dementia}}, journal = {The Lancet. Neurology}, year = {2020}, doi = {10.1016/s1474-4422(19)30153-x}, pmid = {31519472}, url = {https://doi.org/10.1016/s1474-4422(19)30153-x} } @article{lozano2016-27567810, author = {Lozano, A. M. and Fosdick, L. and Chakravarty, M. M. and Leoutsakos, J. M. and Munro, C. and Oh, E. and Drake, K. E. and Lyman, C. H. and others}, title = {{A Phase II Study of Fornix Deep Brain Stimulation in Mild Alzheimer's Disease}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2016}, doi = {10.3233/jad-160017}, pmid = {27567810}, url = {https://doi.org/10.3233/jad-160017} } @article{blennow2019-31836810, author = {Blennow, K. and Shaw, L. M. and Stomrud, E. and Mattsson, N. and Toledo, J. B. and Buck, K. and Wahl, S. and Eichenlaub, U. and others}, title = {{Predicting clinical decline and conversion to Alzheimer's disease or dementia using novel Elecsys Aβ(1-42), pTau and tTau CSF immunoassays}}, journal = {Scientific reports}, year = {2019}, doi = {10.1038/s41598-019-54204-z}, pmid = {31836810}, url = {https://doi.org/10.1038/s41598-019-54204-z} } @article{sevigny2024-38745011, author = {Sevigny, J. and Uspenskaya, O. and Heckman, L. D. and Wong, L. C. and Hatch, D. A. and Tewari, A. and Vandenberghe, R. and Irwin, D. J. and others}, title = {{Progranulin AAV gene therapy for frontotemporal dementia: translational studies and phase 1/2 trial interim results}}, journal = {Nature medicine}, year = {2024}, doi = {10.1038/s41591-024-02973-0}, pmid = {38745011}, url = {https://doi.org/10.1038/s41591-024-02973-0} } @article{broce2018-29315334, author = {Broce, I. and Karch, C. M. and Wen, N. and Fan, C. C. and Wang, Y. and Tan, C. H. and Kouri, N. and Ross, O. A. and others}, title = {{Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies}}, journal = {PLoS medicine}, year = {2018}, doi = {10.1371/journal.pmed.1002487}, pmid = {29315334}, url = {https://doi.org/10.1371/journal.pmed.1002487} } @article{atri2024-39713942, author = {Atri, A. and Dickerson, B. C. and Clevenger, C. and Karlawish, J. and Knopman, D. and Lin, P. J. and Norman, M. and Onyike, C. and Sano, M. and Scanland, S. and others}, title = {{Alzheimer's Association clinical practice guideline for the Diagnostic Evaluation, Testing, Counseling, and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD-ADRD): Executive summary of recommendations for primary care}}, journal = {Alzheimer's \& Dementia}, year = {2024}, doi = {10.1002/alz.14333}, pmid = {39713942}, url = {https://doi.org/10.1002/alz.14333} } @article{petersen2026-41714746, author = {Petersen, Kellen K and Milà-Alomà, Marta and Li, Yan and Du, Lianlian and Xiong, Chengjie and Tosun, Duygu and Saef, Benjamin and Saad, Ziad S and others}, title = {{Predicting onset of symptomatic Alzheimer's disease with plasma p-tau217 clocks}}, journal = {Nature medicine}, year = {2026}, doi = {10.1038/s41591-026-04206-y}, pmid = {41714746}, url = {https://doi.org/10.1038/s41591-026-04206-y} } @article{jansen2022-35099509, author = {Jansen, W. J. and Janssen, O. and Tijms, B. M. and Vos, S. J. B. and Ossenkoppele, R. and Visser, P. J. and {Amyloid Biomarker Study Group} and Aarsland, D. and others}, title = {{Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum}}, journal = {JAMA neurology}, year = {2022}, doi = {10.1001/jamaneurol.2021.5216}, pmid = {35099509}, url = {https://doi.org/10.1001/jamaneurol.2021.5216} } @article{sargurupremraj2020-33293549, author = {Sargurupremraj, M. and Suzuki, H. and Jian, X. and Sarnowski, C. and Evans, T. E. and Bis, J. C. and Eiriksdottir, G. and Sakaue, S. and others}, title = {{Cerebral small vessel disease genomics and its implications across the lifespan}}, journal = {Nature communications}, year = {2020}, doi = {10.1038/s41467-020-19111-2}, pmid = {33293549}, url = {https://doi.org/10.1038/s41467-020-19111-2} } @article{driscoll2009-19487648, author = {Driscoll, I. and Davatzikos, C. and An, Y. and Wu, X. and Shen, D. and Kraut, M. and Resnick, S. M.}, title = {{Longitudinal pattern of regional brain volume change differentiates normal aging from MCI}}, journal = {Neurology}, year = {2009}, doi = {10.1212/wnl.0b013e3181a82634}, pmid = {19487648}, url = {https://doi.org/10.1212/wnl.0b013e3181a82634} } @article{johnson2013-23365092, author = {Johnson, V. E. and Stewart, J. E. and Begbie, F. D. and Trojanowski, J. Q. and Smith, D. H. and Stewart, W.}, title = {{Inflammation and white matter degeneration persist for years after a single traumatic brain injury}}, journal = {Brain : a journal of neurology}, year = {2013}, doi = {10.1093/brain/aws322}, pmid = {23365092}, url = {https://doi.org/10.1093/brain/aws322} } @article{peter2025-40513084, author = {Peter, Christopher and Sathe, Aditi and Shashikumar, Niranjana and Pechman, Kimberly R. and Workmeister, Abigail W. and Jackson, Trevor Bryan and Huo, Yuankai and Mukherjee, Shubhabrata and others}, title = {{White Matter Abnormalities and Cognition in Aging and Alzheimer Disease}}, journal = {JAMA Neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.1601}, pmid = {40513084}, url = {https://doi.org/10.1001/jamaneurol.2025.1601} } @article{tsuang2013-23407718, author = {Tsuang, D. and Leverenz, J. B. and Lopez, O. L. and Hamilton, R. L. and Bennett, D. A. and Schneider, J. A. and Buchman, A. S. and Larson, E. B. and others}, title = {{APOE ε4 increases risk for dementia in pure synucleinopathies}}, journal = {JAMA neurology}, year = {2013}, doi = {10.1001/jamaneurol.2013.600}, pmid = {23407718}, url = {https://doi.org/10.1001/jamaneurol.2013.600} } @article{miyashita2013-23565137, author = {Miyashita, A. and Koike, A. and Jun, G. and Wang, L. S. and Takahashi, S. and Matsubara, E. and Kawarabayashi, T. and Shoji, M. and others}, title = {{SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians}}, journal = {PloS one}, year = {2013}, doi = {10.1371/journal.pone.0058618}, pmid = {23565137}, url = {https://doi.org/10.1371/journal.pone.0058618} } @article{verhaaren2015-25663218, author = {Verhaaren, B. F. and Debette, S. and Bis, J. C. and Smith, J. A. and Ikram, M. K. and Adams, H. H. and Beecham, A. H. and Rajan, K. B. and others}, title = {{Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI}}, journal = {Circulation. Cardiovascular genetics}, year = {2015}, doi = {10.1161/circgenetics.114.000858}, pmid = {25663218}, url = {https://doi.org/10.1161/circgenetics.114.000858} } @article{fleisher2008-18695053, author = {Fleisher, A. S. and Raman, R. and Siemers, E. R. and Becerra, L. and Clark, C. M. and Dean, R. A. and Farlow, M. R. and Galvin, J. E. and others}, title = {{Phase 2 safety trial targeting amyloid beta production with a gamma-secretase inhibitor in Alzheimer disease}}, journal = {Archives of neurology}, year = {2008}, doi = {10.1001/archneur.65.8.1031}, pmid = {18695053}, url = {https://doi.org/10.1001/archneur.65.8.1031} } @article{williamson2007-17599421, author = {Williamson, J. D. and Miller, M. E. and Bryan, R. N. and Lazar, R. M. and Coker, L. H. and Johnson, J. and Cukierman, T. and Horowitz, K. R. and others}, title = {{The Action to Control Cardiovascular Risk in Diabetes Memory in Diabetes Study (ACCORD-MIND): rationale, design, and methods}}, journal = {The American journal of cardiology}, year = {2007}, doi = {10.1016/j.amjcard.2007.03.029}, pmid = {17599421}, url = {https://doi.org/10.1016/j.amjcard.2007.03.029} } @article{habes2023-37261829, author = {Habes, M. and Jacobson, A. M. and Braffett, B. H. and Rashid, T. and Ryan, C. M. and Shou, H. and Cui, Y. and Davatzikos, C. and others}, title = {{Patterns of Regional Brain Atrophy and Brain Aging in Middle- and Older-Aged Adults With Type 1 Diabetes}}, journal = {JAMA network open}, year = {2023}, doi = {10.1001/jamanetworkopen.2023.16182}, pmid = {37261829}, url = {https://doi.org/10.1001/jamanetworkopen.2023.16182} } @article{wilson2007-17283291, author = {Wilson, R. S. and Krueger, K. R. and Arnold, S. E. and Schneider, J. A. and Kelly, J. F. and Barnes, L. L. and Tang, Y. and Bennett, D. A.}, title = {{Loneliness and risk of Alzheimer disease}}, journal = {Archives of general psychiatry}, year = {2007}, doi = {10.1001/archpsyc.64.2.234}, pmid = {17283291}, url = {https://doi.org/10.1001/archpsyc.64.2.234} } @article{fleisher2020-32338734, author = {Fleisher, A. S. and Pontecorvo, M. J. and Devous, M. D. and Lu, M. and Arora, A. K. and Truocchio, S. P. and Aldea, P. and Flitter, M. and others}, title = {{Positron Emission Tomography Imaging With [18F]flortaucipir and Postmortem Assessment of Alzheimer Disease Neuropathologic Changes}}, journal = {JAMA neurology}, year = {2020}, doi = {10.1001/jamaneurol.2020.0528}, pmid = {32338734}, url = {https://doi.org/10.1001/jamaneurol.2020.0528} } @article{koenig2017-28538088, author = {Koenig, A. M. and Mechanic-Hamilton, D. and Xie, S. X. and Combs, M. F. and Cappola, A. R. and Xie, L. and Detre, J. A. and Wolk, D. A. and others}, title = {{Effects of the Insulin Sensitizer Metformin in Alzheimer Disease: Pilot Data From a Randomized Placebo-controlled Crossover Study}}, journal = {Alzheimer disease and associated disorders}, year = {2017}, doi = {10.1097/wad.0000000000000202}, pmid = {28538088}, url = {https://doi.org/10.1097/wad.0000000000000202} } @article{jagust2010-20451870, author = {Jagust, W. J. and Bandy, D. and Chen, K. and Foster, N. L. and Landau, S. M. and Mathis, C. A. and Price, J. C. and Reiman, E. M. and others}, title = {{The Alzheimer's Disease Neuroimaging Initiative positron emission tomography core}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2010}, doi = {10.1016/j.jalz.2010.03.003}, pmid = {20451870}, url = {https://doi.org/10.1016/j.jalz.2010.03.003} } @article{suarezcalvet2019-30630532, author = {Suárez-Calvet, M. and Morenas-Rodríguez, E. and Kleinberger, G. and Schlepckow, K. and MÁ, Araque Caballero and Franzmeier, N. and Capell, A. and Fellerer, K. and others}, title = {{Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-β pathology}}, journal = {Molecular neurodegeneration}, year = {2019}, doi = {10.1186/s13024-018-0301-5}, pmid = {30630532}, url = {https://doi.org/10.1186/s13024-018-0301-5} } @article{benitez2014-24439484, author = {Benitez, B. A. and Jin, S. C. and Guerreiro, R. and Graham, R. and Lord, J. and Harold, D. and Sims, R. and Lambert, J. C. and others}, title = {{Missense variant in TREML2 protects against Alzheimer's disease}}, journal = {Neurobiology of aging}, year = {2014}, doi = {10.1016/j.neurobiolaging.2013.12.010}, pmid = {24439484}, url = {https://doi.org/10.1016/j.neurobiolaging.2013.12.010} } @article{nho2019-31365104, author = {Nho, K. and Kueider-Paisley, A. and Ahmad, S. and MahmoudianDehkordi, S. and Arnold, M. and Risacher, S. L. and Louie, G. and Blach, C. and others}, title = {{Association of Altered Liver Enzymes With Alzheimer Disease Diagnosis, Cognition, Neuroimaging Measures, and Cerebrospinal Fluid Biomarkers}}, journal = {JAMA network open}, year = {2019}, doi = {10.1001/jamanetworkopen.2019.7978}, pmid = {31365104}, url = {https://doi.org/10.1001/jamanetworkopen.2019.7978} } @article{weiner2015-26073027, author = {Weiner, M. W. and Veitch, D. P. and Aisen, P. S. and Beckett, L. A. and Cairns, N. J. and Cedarbaum, J. and Green, R. C. and Harvey, D. and others}, title = {{2014 Update of the Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2015}, doi = {10.1016/j.jalz.2014.11.001}, pmid = {26073027}, url = {https://doi.org/10.1016/j.jalz.2014.11.001} } @article{olsson2019-30508027, author = {Olsson, B. and Portelius, E. and Cullen, N. C. and Å, Sandelius and Zetterberg, H. and Andreasson, U. and Höglund, K. and Irwin, D. J. and others}, title = {{Association of Cerebrospinal Fluid Neurofilament Light Protein Levels With Cognition in Patients With Dementia, Motor Neuron Disease, and Movement Disorders}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2018.3746}, pmid = {30508027}, url = {https://doi.org/10.1001/jamaneurol.2018.3746} } @article{bernath2020-32358220, author = {Bernath, M. M. and Bhattacharyya, S. and Nho, K. and Barupal, D. K. and Fiehn, O. and Baillie, R. and Risacher, S. L. and Arnold, M. and others}, title = {{Serum triglycerides in Alzheimer disease: Relation to neuroimaging and CSF biomarkers}}, journal = {Neurology}, year = {2020}, doi = {10.1212/wnl.0000000000009436}, pmid = {32358220}, url = {https://doi.org/10.1212/wnl.0000000000009436} } @article{schrag2017-27866858, author = {Schrag, A. and Siddiqui, U. F. and Anastasiou, Z. and Weintraub, D. and Schott, J. M.}, title = {{Clinical variables and biomarkers in prediction of cognitive impairment in patients with newly diagnosed Parkinson's disease: a cohort study}}, journal = {The Lancet. Neurology}, year = {2017}, doi = {10.1016/s1474-4422(16)30328-3}, pmid = {27866858}, url = {https://doi.org/10.1016/s1474-4422(16)30328-3} } @article{irwin2017-27979356, author = {Irwin, D. J. and Grossman, M. and Weintraub, D. and Hurtig, H. I. and Duda, J. E. and Xie, S. X. and Lee, E. B. and Van Deerlin, V. M. and others}, title = {{Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis}}, journal = {The Lancet. Neurology}, year = {2017}, doi = {10.1016/s1474-4422(16)30291-5}, pmid = {27979356}, url = {https://doi.org/10.1016/s1474-4422(16)30291-5} } @article{holstege2022-36411364, author = {Holstege, H. and Hulsman, M. and Charbonnier, C. and Grenier-Boley, B. and Quenez, O. and Grozeva, D. and van Rooij, J. G. J. and Sims, R. and others}, title = {{Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease}}, journal = {Nature genetics}, year = {2022}, doi = {10.1038/s41588-022-01208-7}, pmid = {36411364}, url = {https://doi.org/10.1038/s41588-022-01208-7} } @article{katz1999-10084637, author = {Katz, I. R. and Jeste, D. V. and Mintzer, J. E. and Clyde, C. and Napolitano, J. and Brecher, M.}, title = {{Comparison of risperidone and placebo for psychosis and behavioral disturbances associated with dementia: a randomized, double-blind trial. Risperidone Study Group}}, journal = {The Journal of clinical psychiatry}, year = {1999}, doi = {10.4088/jcp.v60n0207}, pmid = {10084637}, url = {https://doi.org/10.4088/jcp.v60n0207} } @article{hansson2018-29499171, author = {Hansson, O. and Seibyl, J. and Stomrud, E. and Zetterberg, H. and Trojanowski, J. Q. and Bittner, T. and Lifke, V. and Corradini, V. and others}, title = {{CSF biomarkers of Alzheimer's disease concord with amyloid-β PET and predict clinical progression: A study of fully automated immunoassays in BioFINDER and ADNI cohorts}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2018}, doi = {10.1016/j.jalz.2018.01.010}, pmid = {29499171}, url = {https://doi.org/10.1016/j.jalz.2018.01.010} } @article{ayton2015-25988319, author = {Ayton, S. and Faux, N. G. and Bush, A. I. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE}}, journal = {Nature communications}, year = {2015}, doi = {10.1038/ncomms7760}, pmid = {25988319}, url = {https://doi.org/10.1038/ncomms7760} } @article{pigott2015-26362285, author = {Pigott, K. and Rick, J. and Xie, S. X. and Hurtig, H. and Chen-Plotkin, A. and Duda, J. E. and Morley, J. F. and Chahine, L. M. and others}, title = {{Longitudinal study of normal cognition in Parkinson disease}}, journal = {Neurology}, year = {2015}, doi = {10.1212/wnl.0000000000002001}, pmid = {26362285}, url = {https://doi.org/10.1212/wnl.0000000000002001} } @article{miyagawa2020-31914218, author = {Miyagawa, T. and Brushaber, D. and Syrjanen, J. and Kremers, W. and Fields, J. and Forsberg, L. K. and Heuer, H. W. and Knopman, D. and others}, title = {{Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2020}, doi = {10.1002/alz.12033}, pmid = {31914218}, url = {https://doi.org/10.1002/alz.12033} } @article{godrich2025-41208712, author = {Godrich, Dana and Pasteris, Jeremy and Martin, Eden R. and Kunkle, Brian W. and Naj, Adam Christian and Hamilton, Kara and Wang, Hui and Lee, Wan‐Ping and others}, title = {{Genome‐wide association studies of TDP‐43 proteinopathy and hippocampal sclerosis reveal shared genetic associations with APOE and TMEM106B}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70760}, pmid = {41208712}, url = {https://doi.org/10.1002/alz.70760} } @article{sharma2026-41985132, author = {Sharma, Mukul and Dong, Qiang and Hirano, Teruyuki and Kasner, Scott Eric and Saver, Jeffrey L. and Masjuan, Jaime and Demchuk, Andrew M. and Cordonnier, Charlotte and others}, title = {{Asundexian for Secondary Stroke Prevention}}, journal = {New England Journal of Medicine}, year = {2026}, doi = {10.1056/nejmoa2513880}, pmid = {41985132}, url = {https://doi.org/10.1056/nejmoa2513880} } @article{zetterberg2016-26524180, author = {Zetterberg, H. and Skillbäck, T. and Mattsson, N. and Trojanowski, J. Q. and Portelius, E. and Shaw, L. M. and Weiner, M. W. and Blennow, K. and others}, title = {{Association of Cerebrospinal Fluid Neurofilament Light Concentration With Alzheimer Disease Progression}}, journal = {JAMA neurology}, year = {2016}, doi = {10.1001/jamaneurol.2015.3037}, pmid = {26524180}, url = {https://doi.org/10.1001/jamaneurol.2015.3037} } @article{khalil2024-38609644, author = {Khalil, M. and Teunissen, C. E. and Lehmann, S. and Otto, M. and Piehl, F. and Ziemssen, T. and Bittner, S. and Sormani, M. P. and others}, title = {{Neurofilaments as biomarkers in neurological disorders - towards clinical application}}, journal = {Nature reviews. Neurology}, year = {2024}, doi = {10.1038/s41582-024-00955-x}, pmid = {38609644}, url = {https://doi.org/10.1038/s41582-024-00955-x} } @article{li2022-34906975, author = {Li, Y. and Schindler, S. E. and Bollinger, J. G. and Ovod, V. and Mawuenyega, K. G. and Weiner, M. W. and Shaw, L. M. and Masters, C. L. and others}, title = {{Validation of Plasma Amyloid-β 42/40 for Detecting Alzheimer Disease Amyloid Plaques}}, journal = {Neurology}, year = {2022}, doi = {10.1212/wnl.0000000000013211}, pmid = {34906975}, url = {https://doi.org/10.1212/wnl.0000000000013211} } @article{nelson2019-31039256, author = {Nelson, P. T. and Dickson, D. W. and Trojanowski, J. Q. and Jack, C. R. and Boyle, P. A. and Arfanakis, K. and Rademakers, R. and Alafuzoff, I. and others}, title = {{Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report}}, journal = {Brain : a journal of neurology}, year = {2019}, doi = {10.1093/brain/awz099}, pmid = {31039256}, url = {https://doi.org/10.1093/brain/awz099} } @article{hoops2009-19933974, author = {Hoops, S. and Nazem, S. and Siderowf, A. D. and Duda, J. E. and Xie, S. X. and Stern, M. B. and Weintraub, D.}, title = {{Validity of the MoCA and MMSE in the detection of MCI and dementia in Parkinson disease}}, journal = {Neurology}, year = {2009}, doi = {10.1212/wnl.0b013e3181c34b47}, pmid = {19933974}, url = {https://doi.org/10.1212/wnl.0b013e3181c34b47} } @article{perry2017-29053860, author = {Perry, D. C. and Brown, J. A. and Possin, K. L. and Datta, S. and Trujillo, A. and Radke, A. and Karydas, A. and Kornak, J. and others}, title = {{Clinicopathological correlations in behavioural variant frontotemporal dementia}}, journal = {Brain : a journal of neurology}, year = {2017}, doi = {10.1093/brain/awx254}, pmid = {29053860}, url = {https://doi.org/10.1093/brain/awx254} } @article{armstrong2019-31268512, author = {Armstrong, N. M. and An, Y. and Doshi, J. and Erus, G. and Ferrucci, L. and Davatzikos, C. and Deal, J. A. and Lin, F. R. and others}, title = {{Association of Midlife Hearing Impairment With Late-Life Temporal Lobe Volume Loss}}, journal = {JAMA otolaryngology-- head \& neck surgery}, year = {2019}, doi = {10.1001/jamaoto.2019.1610}, pmid = {31268512}, url = {https://doi.org/10.1001/jamaoto.2019.1610} } @article{varma2021-34043628, author = {Varma, V. R. and Wang, Y. and An, Y. and Varma, S. and Bilgel, M. and Doshi, J. and Legido-Quigley, C. and Delgado, J. C. and others}, title = {{Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study}}, journal = {PLoS medicine}, year = {2021}, doi = {10.1371/journal.pmed.1003615}, pmid = {34043628}, url = {https://doi.org/10.1371/journal.pmed.1003615} } @article{langa2008-18631957, author = {Langa, K. M. and Larson, E. B. and Karlawish, J. H. and Cutler, D. M. and Kabeto, M. U. and Kim, S. Y. and Rosen, A. B.}, title = {{Trends in the prevalence and mortality of cognitive impairment in the United States: is there evidence of a compression of cognitive morbidity?}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2008}, doi = {10.1016/j.jalz.2008.01.001}, pmid = {18631957}, url = {https://doi.org/10.1016/j.jalz.2008.01.001} } @article{majounie2012-22406228, author = {Majounie, E. and Renton, A. E. and Mok, K. and Dopper, E. G. and Waite, A. and Rollinson, S. and Chiò, A. and Restagno, G. and others}, title = {{Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study}}, journal = {The Lancet. Neurology}, year = {2012}, doi = {10.1016/s1474-4422(12)70043-1}, pmid = {22406228}, url = {https://doi.org/10.1016/s1474-4422(12)70043-1} } @article{stokes2020-32852519, author = {Stokes, A. C. and Weiss, J. and Lundberg, D. J. and Xie, W. and Kim, J. K. and Preston, S. H. and Crimmins, E. M.}, title = {{Estimates of the Association of Dementia With US Mortality Levels Using Linked Survey and Mortality Records}}, journal = {JAMA neurology}, year = {2020}, doi = {10.1001/jamaneurol.2020.2831}, pmid = {32852519}, url = {https://doi.org/10.1001/jamaneurol.2020.2831} } @article{schneider2021-33687142, author = {Schneider, A. L. C. and Selvin, E. and Latour, L. and Turtzo, L. C. and Coresh, J. and Mosley, T. and Ling, G. and Gottesman, R. F.}, title = {{Head injury and 25-year risk of dementia}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2021}, doi = {10.1002/alz.12315}, pmid = {33687142}, url = {https://doi.org/10.1002/alz.12315} } @article{seppi2019-30653247, author = {Seppi, K. and Ray Chaudhuri, K. and Coelho, M. and Fox, S. H. and Katzenschlager, R. and Perez Lloret, S. and Weintraub, D. and Sampaio, C. and others}, title = {{Update on treatments for nonmotor symptoms of Parkinson's disease-an evidence-based medicine review}}, journal = {Movement disorders : official journal of the Movement Disorder Society}, year = {2019}, doi = {10.1002/mds.27602}, pmid = {30653247}, url = {https://doi.org/10.1002/mds.27602} } @article{young2018-30323170, author = {Young, A. L. and Marinescu, R. V. and Oxtoby, N. P. and Bocchetta, M. and Yong, K. and Firth, N. C. and Cash, D. M. and Thomas, D. L. and others}, title = {{Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference}}, journal = {Nature communications}, year = {2018}, doi = {10.1038/s41467-018-05892-0}, pmid = {30323170}, url = {https://doi.org/10.1038/s41467-018-05892-0} } @article{doraiswamy2012-22786606, author = {Doraiswamy, P. M. and Sperling, R. A. and Coleman, R. E. and Johnson, K. A. and Reiman, E. M. and Davis, M. D. and Grundman, M. and Sabbagh, M. N. and others}, title = {{Amyloid-β assessed by florbetapir F 18 PET and 18-month cognitive decline: a multicenter study}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e3182661f74}, pmid = {22786606}, url = {https://doi.org/10.1212/wnl.0b013e3182661f74} } @article{shaw2009-19296504, author = {Shaw, Leslie M. and Vanderstichele, Hugo and Knapik-Czajka, Malgorzata Elzbieta and Clark, Christopher M. and Aisen, Paul S. S. and Petersen, Ronald Carl and Blennow, Kaj and Soares, Holly D and others}, title = {{Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects}}, journal = {Annals of Neurology}, year = {2009}, doi = {10.1002/ana.21610}, pmid = {19296504}, url = {https://doi.org/10.1002/ana.21610} } @article{vandevrede2023-37010841, author = {VandeVrede, L. and La Joie, R. and Thijssen, E. H. and Asken, B. M. and Vento, S. A. and Tsuei, T. and Baker, S. L. and Cobigo, Y. and others}, title = {{Evaluation of Plasma Phosphorylated Tau217 for Differentiation Between Alzheimer Disease and Frontotemporal Lobar Degeneration Subtypes Among Patients With Corticobasal Syndrome}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.0488}, pmid = {37010841}, url = {https://doi.org/10.1001/jamaneurol.2023.0488} } @article{safarpour2015-26138947, author = {Safarpour, D. and Thibault, D. P. and DeSanto, C. L. and Boyd, C. M. and Dorsey, E. R. and Racette, B. A. and Willis, A. W.}, title = {{Nursing home and end-of-life care in Parkinson disease}}, journal = {Neurology}, year = {2015}, doi = {10.1212/wnl.0000000000001715}, pmid = {26138947}, url = {https://doi.org/10.1212/wnl.0000000000001715} } @article{vandeerlin2010-20154673, author = {Van Deerlin, V. M. and Sleiman, P. M. and Martinez-Lage, M. and Chen-Plotkin, A. and Wang, L. S. and Graff-Radford, N. R. and Dickson, D. W. and Rademakers, R. and others}, title = {{Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions}}, journal = {Nature genetics}, year = {2010}, doi = {10.1038/ng.536}, pmid = {20154673}, url = {https://doi.org/10.1038/ng.536} } @article{robinson2018-29878075, author = {Robinson, J. L. and Lee, E. B. and Xie, S. X. and Rennert, L. and Suh, E. and Bredenberg, C. and Caswell, C. and Van Deerlin, V. M. and others}, title = {{Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated}}, journal = {Brain : a journal of neurology}, year = {2018}, doi = {10.1093/brain/awy146}, pmid = {29878075}, url = {https://doi.org/10.1093/brain/awy146} } @article{bellenguez2022-35379992, author = {Bellenguez, C. and Küçükali, F. and Jansen, I. E. and Kleineidam, L. and Moreno-Grau, S. and Amin, N. and Naj, A. C. and Campos-Martin, R. and others}, title = {{New insights into the genetic etiology of Alzheimer's disease and related dementias}}, journal = {Nature genetics}, year = {2022}, doi = {10.1038/s41588-022-01024-z}, pmid = {35379992}, url = {https://doi.org/10.1038/s41588-022-01024-z} } @article{davis2016-27571329, author = {Davis, M. Y. and Johnson, C. O. and Leverenz, J. B. and Weintraub, D. and Trojanowski, J. Q. and Chen-Plotkin, A. and Van Deerlin, V. M. and Quinn, J. F. and others}, title = {{Association of GBA Mutations and the E326K Polymorphism With Motor and Cognitive Progression in Parkinson Disease}}, journal = {JAMA neurology}, year = {2016}, doi = {10.1001/jamaneurol.2016.2245}, pmid = {27571329}, url = {https://doi.org/10.1001/jamaneurol.2016.2245} } @article{lee2019-30760848, author = {Lee, G. and Nho, K. and Kang, B. and Sohn, K. A. and Kim, D. and {for Alzheimer’s Disease Neuroimaging Initiative}}, title = {{Predicting Alzheimer's disease progression using multi-modal deep learning approach}}, journal = {Scientific reports}, year = {2019}, doi = {10.1038/s41598-018-37769-z}, pmid = {30760848}, url = {https://doi.org/10.1038/s41598-018-37769-z} } @article{toledo2011-21805181, author = {Toledo, J. B. and Vanderstichele, H. and Figurski, M. and Aisen, P. S. and Petersen, R. C. and Weiner, M. W. and Jack, C. R. and Jagust, W. and others}, title = {{Factors affecting Aβ plasma levels and their utility as biomarkers in ADNI}}, journal = {Acta neuropathologica}, year = {2011}, doi = {10.1007/s00401-011-0861-8}, pmid = {21805181}, url = {https://doi.org/10.1007/s00401-011-0861-8} } @article{tariot2001-11843990, author = {Tariot, P. N. and Cummings, J. L. and Katz, I. R. and Mintzer, J. and Perdomo, C. A. and Schwam, E. M. and Whalen, E.}, title = {{A randomized, double-blind, placebo-controlled study of the efficacy and safety of donepezil in patients with Alzheimer's disease in the nursing home setting}}, journal = {Journal of the American Geriatrics Society}, year = {2001}, doi = {10.1111/j.1532-5415.2001.49266.x}, pmid = {11843990}, url = {https://doi.org/10.1111/j.1532-5415.2001.49266.x} } @article{wen2022-35262657, author = {Wen, J. and Fu, C. H. Y. and Tosun, D. and Veturi, Y. and Yang, Z. and Abdulkadir, A. and Mamourian, E. and Srinivasan, D. and others}, title = {{Characterizing Heterogeneity in Neuroimaging, Cognition, Clinical Symptoms, and Genetics Among Patients With Late-Life Depression}}, journal = {JAMA psychiatry}, year = {2022}, doi = {10.1001/jamapsychiatry.2022.0020}, pmid = {35262657}, url = {https://doi.org/10.1001/jamapsychiatry.2022.0020} } @article{leuzy2023-37155176, author = {Leuzy, A. and Binette, A. P. and Vogel, J. W. and Klein, G. and Borroni, E. and Tonietto, M. and Strandberg, O. and Mattsson-Carlgren, N. and others}, title = {{Comparison of Group-Level and Individualized Brain Regions for Measuring Change in Longitudinal Tau Positron Emission Tomography in Alzheimer Disease}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.1067}, pmid = {37155176}, url = {https://doi.org/10.1001/jamaneurol.2023.1067} } @article{lambert2013-24162737, author = {Lambert, Jean‐Charles and Ibrahim‐Verbaas, Carla A. and Harold, Denise H. and Naj, Adam Christian and Sims, Rebecca and Bellenguez, Céline and others}, title = {{Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease}}, journal = {Nature Genetics}, year = {2013}, doi = {10.1038/ng.2802}, pmid = {24162737}, url = {https://doi.org/10.1038/ng.2802} } @article{aarsland2017-28257128, author = {Aarsland, D. and Creese, B. and Politis, M. and Chaudhuri, K. R. and Ffytche, D. H. and Weintraub, D. and Ballard, C.}, title = {{Cognitive decline in Parkinson disease}}, journal = {Nature reviews. Neurology}, year = {2017}, doi = {10.1038/nrneurol.2017.27}, pmid = {28257128}, url = {https://doi.org/10.1038/nrneurol.2017.27} } @article{tariot2006-16905684, author = {Tariot, P. N. and Schneider, L. and Katz, I. R. and Mintzer, J. E. and Street, J. and Copenhaver, M. and Williams-Hughes, C.}, title = {{Quetiapine treatment of psychosis associated with dementia: a double-blind, randomized, placebo-controlled clinical trial}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2006}, doi = {10.1097/01.jgp.0000196628.12010.35}, pmid = {16905684}, url = {https://doi.org/10.1097/01.jgp.0000196628.12010.35} } @article{rascovsky2011-21810890, author = {Rascovsky, K. and Hodges, JR. and Knopman, D. and Mendez, M. F. and Kramer, J. H. and Neuhaus, J. and van Swieten, J. C. and Seelaar, H. and others}, title = {{Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia}}, journal = {Brain : a journal of neurology}, year = {2011}, doi = {10.1093/brain/awr179}, pmid = {21810890}, url = {https://doi.org/10.1093/brain/awr179} } @article{attems2021-33399945, author = {Attems, J. and Toledo, J. B. and Walker, L. and Gelpi, E. and Gentleman, S. and Halliday, G. and Hortobagyi, T. and Jellinger, K. and others}, title = {{Neuropathological consensus criteria for the evaluation of Lewy pathology in post-mortem brains: a multi-centre study}}, journal = {Acta neuropathologica}, year = {2021}, doi = {10.1007/s00401-020-02255-2}, pmid = {33399945}, url = {https://doi.org/10.1007/s00401-020-02255-2} } @article{aarsland2010-20855849, author = {Aarsland, D. and Bronnick, K. and Williams-Gray, C. and Weintraub, D. and Marder, K. and Kulisevsky, J. and Burn, D. and Barone, P. and others}, title = {{Mild cognitive impairment in Parkinson disease: a multicenter pooled analysis}}, journal = {Neurology}, year = {2010}, doi = {10.1212/wnl.0b013e3181f39d0e}, pmid = {20855849}, url = {https://doi.org/10.1212/wnl.0b013e3181f39d0e} } @article{weiner2017-28342697, author = {Weiner, M. W. and Veitch, D. P. and Aisen, P. S. and Beckett, L. A. and Cairns, N. J. and Green, R. C. and Harvey, D. and Jack, C. R. and others}, title = {{Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2017}, doi = {10.1016/j.jalz.2016.11.007}, pmid = {28342697}, url = {https://doi.org/10.1016/j.jalz.2016.11.007} } @article{dong2017-28003242, author = {Dong, A. and Toledo, J. B. and Honnorat, N. and Doshi, J. and Varol, E. and Sotiras, A. and Wolk, D. and Trojanowski, J. Q. and others}, title = {{Heterogeneity of neuroanatomical patterns in prodromal Alzheimer's disease: links to cognition, progression and biomarkers}}, journal = {Brain : a journal of neurology}, year = {2017}, doi = {10.1093/brain/aww319}, pmid = {28003242}, url = {https://doi.org/10.1093/brain/aww319} } @article{zhao2020-36659162, author = {Zhao, K. and Ding, Y. and Han, Y. and Fan, Y. and Alexander-Bloch, A. F. and Han, T. and Jin, D. and Liu, B. and others}, title = {{Independent and reproducible hippocampal radiomic biomarkers for multisite Alzheimer's disease: diagnosis, longitudinal progress and biological basis}}, journal = {Science bulletin}, year = {2020}, doi = {10.1016/j.scib.2020.04.003}, pmid = {36659162}, url = {https://doi.org/10.1016/j.scib.2020.04.003} } @article{richards2025-39909068, author = {Richards, Kathy Culpepper and Fry, Liam and Lozano, Alicia J and Ji, Wenyan and Morrison, Janet and Britt, Katherine Carroll and Bliwise, Donald L. and Gooneratne, Nalaka Sudheera and others}, title = {{Treatment of Restless Legs Syndrome Improves Agitation and Sleep in Persons with Dementia: A Randomized Trial}}, journal = {Journal of the American Medical Directors Association}, year = {2025}, doi = {10.1016/j.jamda.2025.105485}, pmid = {39909068}, url = {https://doi.org/10.1016/j.jamda.2025.105485} } @article{cousins2025-40801297, author = {Cousins, K. A. Q. and Korecka, M. and Wan, Y. and Vulaj, A. and Brown, C. and Tropea, T. F. and Lee, E. B. and Tosun, D. and Landau, S. M. and Okonkwo, O. C. and Mindt, M. R. and Weiner, M. W. and others}, title = {{Comparison of plasma p-tau217/Aβ42, p-tau217, and Aβ42/Aβ40 biomarkers by race to detect Alzheimer's disease}}, journal = {Alzheimer's \& Dementia}, year = {2025}, doi = {10.1002/alz.70469}, pmid = {40801297}, url = {https://doi.org/10.1002/alz.70469} } @article{habes2018-30076276, author = {Habes, M. and Sotiras, A. and Erus, G. and Toledo, J. B. and Janowitz, D. and Wolk, D. A. and Shou, H. and Bryan, N. R. and others}, title = {{White matter lesions: Spatial heterogeneity, links to risk factors, cognition, genetics, and atrophy}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000006116}, pmid = {30076276}, url = {https://doi.org/10.1212/wnl.0000000000006116} } @article{streim2008-18591574, author = {Streim, J. E. and Porsteinsson, A. P. and Breder, C. D. and Swanink, R. and Marcus, R. and McQuade, R. and Carson, W. H.}, title = {{A randomized, double-blind, placebo-controlled study of aripiprazole for the treatment of psychosis in nursing home patients with Alzheimer disease}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2008}, doi = {10.1097/jgp.0b013e318165db77}, pmid = {18591574}, url = {https://doi.org/10.1097/jgp.0b013e318165db77} } @article{munro2012-23032478, author = {Munro, C. A. and Longmire, C. F. and Drye, L. T. and Martin, B. K. and Frangakis, C. E. and Meinert, C. L. and Mintzer, J. E. and Porsteinsson, A. P. and others}, title = {{Cognitive outcomes after sertaline treatment in patients with depression of Alzheimer disease}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2012}, doi = {10.1097/jgp.0b013e31826ce4c5}, pmid = {23032478}, url = {https://doi.org/10.1097/jgp.0b013e31826ce4c5} } @article{jack2018-29653606, author = {Jack, C. R. and Bennett, D. A. and Blennow, K. and Carrillo, M. C. and Dunn, B. and Haeberlein, S. B. and Holtzman, D. M. and Jagust, W. and others}, title = {{NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2018}, doi = {10.1016/j.jalz.2018.02.018}, pmid = {29653606}, url = {https://doi.org/10.1016/j.jalz.2018.02.018} } @article{mckeith2005-16237129, author = {McKeith, I. G. and Dickson, D. W. and Lowe, J. and Emre, M. and O'Brien, J. T. and Feldman, H. and Cummings, J. and Duda, J. E. and others}, title = {{Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium}}, journal = {Neurology}, year = {2005}, doi = {10.1212/01.wnl.0000187889.17253.b1}, pmid = {16237129}, url = {https://doi.org/10.1212/01.wnl.0000187889.17253.b1} } @article{habes2016-26912649, author = {Habes, M. and Erus, G. and Toledo, J. B. and Zhang, T. and Bryan, N. and Launer, L. J. and Rosseel, Y. and Janowitz, D. and others}, title = {{White matter hyperintensities and imaging patterns of brain ageing in the general population}}, journal = {Brain : a journal of neurology}, year = {2016}, doi = {10.1093/brain/aww008}, pmid = {26912649}, url = {https://doi.org/10.1093/brain/aww008} } @article{yaffe2016-27397561, author = {Yaffe, K. and Nasrallah, I. and Hoang, T. D. and Lauderdale, D. S. and Knutson, K. L. and Carnethon, M. R. and Launer, L. J. and Lewis, C. E. and others}, title = {{Sleep Duration and White Matter Quality in Middle-Aged Adults}}, journal = {Sleep}, year = {2016}, doi = {10.5665/sleep.6104}, pmid = {27397561}, url = {https://doi.org/10.5665/sleep.6104} } @article{lin2014-24412398, author = {Lin, F. R. and Ferrucci, L. and An, Y. and Goh, J. O. and Doshi, J. and Metter, E. J. and Davatzikos, C. and Kraut, M. A. and others}, title = {{Association of hearing impairment with brain volume changes in older adults}}, journal = {NeuroImage}, year = {2014}, doi = {10.1016/j.neuroimage.2013.12.059}, pmid = {24412398}, url = {https://doi.org/10.1016/j.neuroimage.2013.12.059} } @article{hutton1998-9641683, author = {Hutton, M. and Lendon, C. L. and Rizzu, P. and Baker, M. and Froelich, S. and Houlden, H. and Pickering-Brown, S. and Chakraverty, S. and others}, title = {{Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17}}, journal = {Nature}, year = {1998}, doi = {10.1038/31508}, pmid = {9641683}, url = {https://doi.org/10.1038/31508} } @article{montine2012-22101365, author = {Montine, T. J. and Phelps, C. H. and Beach, T. G. and Bigio, E. H. and Cairns, N. J. and Dickson, D. W. and Duyckaerts, C. and Frosch, M. P. and others}, title = {{National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach}}, journal = {Acta neuropathologica}, year = {2012}, doi = {10.1007/s00401-011-0910-3}, pmid = {22101365}, url = {https://doi.org/10.1007/s00401-011-0910-3} } @article{ma2022-35197626, author = {Ma, X. R. and Prudencio, M. and Koike, Y. and Vatsavayai, S. C. and Kim, G. and Harbinski, F. and Briner, A. and Rodriguez, C. M. and others}, title = {{TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A}}, journal = {Nature}, year = {2022}, doi = {10.1038/s41586-022-04424-7}, pmid = {35197626}, url = {https://doi.org/10.1038/s41586-022-04424-7} } @article{brown2022-35197628, author = {Brown, A. L. and Wilkins, O. G. and Keuss, M. J. and Kargbo-Hill, S. E. and Zanovello, M. and Lee, W. C. and Bampton, A. and Lee, F. C. Y. and others}, title = {{TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A}}, journal = {Nature}, year = {2022}, doi = {10.1038/s41586-022-04436-3}, pmid = {35197628}, url = {https://doi.org/10.1038/s41586-022-04436-3} } @article{chia2021-33589841, author = {Chia, R. and Sabir, M. S. and Bandres-Ciga, S. and Saez-Atienzar, S. and Reynolds, R. H. and Gustavsson, E. and Walton, R. L. and Ahmed, S. and others}, title = {{Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture}}, journal = {Nature genetics}, year = {2021}, doi = {10.1038/s41588-021-00785-3}, pmid = {33589841}, url = {https://doi.org/10.1038/s41588-021-00785-3} } @article{beecham2014-25188341, author = {Beecham, G. W. and Hamilton, K. and Naj, A. C. and Martin, E. R. and Huentelman, M. and Myers, A. J. and Corneveaux, J. J. and Hardy, J. and others}, title = {{Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias}}, journal = {PLoS genetics}, year = {2014}, doi = {10.1371/journal.pgen.1004606}, pmid = {25188341}, url = {https://doi.org/10.1371/journal.pgen.1004606} } @article{thambisetty2012-21824521, author = {Thambisetty, M. and An, Y. and Kinsey, A. and Koka, D. and Saleem, M. and Güntert, A. and Kraut, M. and Ferrucci, L. and others}, title = {{Plasma clusterin concentration is associated with longitudinal brain atrophy in mild cognitive impairment}}, journal = {NeuroImage}, year = {2012}, doi = {10.1016/j.neuroimage.2011.07.056}, pmid = {21824521}, url = {https://doi.org/10.1016/j.neuroimage.2011.07.056} } @article{wilson2013-24080705, author = {Wilson, R. S. and Yu, L. and Trojanowski, J. Q. and Chen, E. Y. and Boyle, P. A. and Bennett, D. A. and Schneider, J. A.}, title = {{TDP-43 pathology, cognitive decline, and dementia in old age}}, journal = {JAMA neurology}, year = {2013}, doi = {10.1001/jamaneurol.2013.3961}, pmid = {24080705}, url = {https://doi.org/10.1001/jamaneurol.2013.3961} } @article{park2020-32227181, author = {Park, Sungchul and White, Lindsay L. Y. and Fishman, Paul Arthur and Larson, Eric B.B. and Coe, Norma B.}, title = {{Health Care Utilization, Care Satisfaction, and Health Status for Medicare Advantage and Traditional Medicare Beneficiaries With and Without Alzheimer Disease and Related Dementias}}, journal = {JAMA Network Open}, year = {2020}, doi = {10.1001/jamanetworkopen.2020.1809}, pmid = {32227181}, url = {https://doi.org/10.1001/jamanetworkopen.2020.1809} } @article{jack2009-20083042, author = {Jack, Clifford R. and Knopman, David S. and Jagust, William J. and Shaw, Leslie M. and Aisen, Paul S. S. and Weiner, Michael Walter and Petersen, Ronald Carl and Trojanowski, John Q.}, title = {{Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade}}, journal = {The Lancet Neurology}, year = {2009}, doi = {10.1016/s1474-4422(09)70299-6}, pmid = {20083042}, url = {https://doi.org/10.1016/s1474-4422(09)70299-6} } @article{jack2013-23332364, author = {Jack, Clifford R. and Knopman, David S. and Jagust, William J. and Petersen, Ronald Carl and Weiner, Michael Walter and Aisen, Paul S. S. and Shaw, Leslie M. and Vemuri, Prashanthi and others}, title = {{Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers}}, journal = {The Lancet Neurology}, year = {2013}, doi = {10.1016/s1474-4422(12)70291-0}, pmid = {23332364}, url = {https://doi.org/10.1016/s1474-4422(12)70291-0} } @article{langbaum2025-41319675, author = {Langbaum, J. B. and Bradbury, A. R. and Egleston, B. L. and McCarty Wood, E. and Langlois, C. M. and Largent, E. A. and Harkins, K. and Erickson, C. M. and Stites, S. D. and Oyen, E. and others}, title = {{Impact of learning APOE genotype on cognitively unimpaired adults: a pre-screening cohort study of the Alzheimer's Prevention Initiative Generation Study 1}}, journal = {The Lancet Healthy Longevity}, year = {2025}, doi = {10.1016/j.lanhl.2025.100778}, pmid = {41319675}, url = {https://doi.org/10.1016/j.lanhl.2025.100778} } @article{zeltzer2025-40720133, author = {Zeltzer, E. and Schonhaut, D. R. and Mundada, N. S. and Blazhenets, G. and Soleimani-Meigooni, D. N. and Cho, H. and Ranasinghe, K. G. and Windon, C. and others}, title = {{Concordance Between Amyloid-PET Quantification and Real-World Visual Reads}}, journal = {JAMA neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.2218}, pmid = {40720133}, url = {https://doi.org/10.1001/jamaneurol.2025.2218} } @article{rajabli2018-30517106, author = {Rajabli, F. and Feliciano, B. E. and Celis, K. and Hamilton-Nelson, K. L. and Whitehead, P. L. and Adams, L. D. and Bussies, P. L. and Manrique, C. P. and others}, title = {{Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations}}, journal = {PLoS genetics}, year = {2018}, doi = {10.1371/journal.pgen.1007791}, pmid = {30517106}, url = {https://doi.org/10.1371/journal.pgen.1007791} } @article{qian2017-28323826, author = {Qian, J. and Wolters, F. J. and Beiser, A. and Haan, M. and Ikram, M. A. and Karlawish, J. and Langbaum, J. B. and Neuhaus, J. M. and others}, title = {{APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts}}, journal = {PLoS medicine}, year = {2017}, doi = {10.1371/journal.pmed.1002254}, pmid = {28323826}, url = {https://doi.org/10.1371/journal.pmed.1002254} } @article{foster2007-17704526, author = {Foster, N. L. and Heidebrink, J. L. and Clark, C. M. and Jagust, W. J. and Arnold, S. E. and Barbas, N. R. and DeCarli, C. S. and Turner, R. S. and others}, title = {{FDG-PET improves accuracy in distinguishing frontotemporal dementia and Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2007}, doi = {10.1093/brain/awm177}, pmid = {17704526}, url = {https://doi.org/10.1093/brain/awm177} } @article{james2016-27694152, author = {James, B. D. and Wilson, R. S. and Boyle, P. A. and Trojanowski, J. Q. and Bennett, D. A. and Schneider, J. A.}, title = {{TDP-43 stage, mixed pathologies, and clinical Alzheimer's-type dementia}}, journal = {Brain : a journal of neurology}, year = {2016}, doi = {10.1093/brain/aww224}, pmid = {27694152}, url = {https://doi.org/10.1093/brain/aww224} } @article{christakis2006-16481639, author = {Christakis, N. A. and Allison, P. D.}, title = {{Mortality after the hospitalization of a spouse}}, journal = {The New England journal of medicine}, year = {2006}, doi = {10.1056/nejmsa050196}, pmid = {16481639}, url = {https://doi.org/10.1056/nejmsa050196} } @article{abuabara2010-20633008, author = {Abuabara, K. and Azfar, R. S. and Shin, D. B. and Neimann, A. L. and Troxel, A. B. and Gelfand, J. M.}, title = {{Cause-specific mortality in patients with severe psoriasis: a population-based cohort study in the U.K}}, journal = {The British journal of dermatology}, year = {2010}, doi = {10.1111/j.1365-2133.2010.09941.x}, pmid = {20633008}, url = {https://doi.org/10.1111/j.1365-2133.2010.09941.x} } @article{hyman2012-22265587, author = {Hyman, B. T. and Phelps, C. H. and Beach, T. G. and Bigio, E. H. and Cairns, N. J. and Carrillo, M. C. and Dickson, D. W. and Duyckaerts, C. and others}, title = {{National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2012}, doi = {10.1016/j.jalz.2011.10.007}, pmid = {22265587}, url = {https://doi.org/10.1016/j.jalz.2011.10.007} } @article{jack2010-20935035, author = {Jack, C. R. and Wiste, H. J. and Vemuri, P. and Weigand, S. D. and Senjem, M. L. and Zeng, G. and Bernstein, M. A. and Gunter, J. L. and others}, title = {{Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2010}, doi = {10.1093/brain/awq277}, pmid = {20935035}, url = {https://doi.org/10.1093/brain/awq277} } @article{leow2009-19280686, author = {Leow, A. D. and Yanovsky, I. and Parikshak, N. and Hua, X. and Lee, S. and Toga, A. W. and Jack, C. R. and Bernstein, M. A. and others}, title = {{Alzheimer's disease neuroimaging initiative: a one-year follow up study using tensor-based morphometry correlating degenerative rates, biomarkers and cognition}}, journal = {NeuroImage}, year = {2009}, doi = {10.1016/j.neuroimage.2009.01.004}, pmid = {19280686}, url = {https://doi.org/10.1016/j.neuroimage.2009.01.004} } @article{katsumata2020-32797255, author = {Katsumata, Y. and Abner, E. L. and Karanth, S. and Teylan, M. A. and Mock, C. N. and Cykowski, M. D. and Lee, E. B. and Boehme, K. L. and others}, title = {{Distinct clinicopathologic clusters of persons with TDP-43 proteinopathy}}, journal = {Acta neuropathologica}, year = {2020}, doi = {10.1007/s00401-020-02211-0}, pmid = {32797255}, url = {https://doi.org/10.1007/s00401-020-02211-0} } @article{mackenzie2007-17469116, author = {Mackenzie, I. R. and Bigio, E. H. and Ince, P. G. and Geser, F. and Neumann, M. and Cairns, N. J. and Kwong, L. K. and Forman, M. S. and others}, title = {{Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations}}, journal = {Annals of neurology}, year = {2007}, doi = {10.1002/ana.21147}, pmid = {17469116}, url = {https://doi.org/10.1002/ana.21147} } @article{kim2025-40920417, author = {Kim, Boram and Blam, Kaitlin and Elser, Holly C. and Xie, Sharon Xiangwen and Van Deerlin, Vivianna M. and Penning, T.M. and Weintraub, Daniel A. and Irwin, David John and others}, title = {{Ambient Air Pollution and the Severity of Alzheimer Disease Neuropathology}}, journal = {JAMA Neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.3316}, pmid = {40920417}, url = {https://doi.org/10.1001/jamaneurol.2025.3316} } @article{grill2026-41910973, author = {Grill, Joshua D. and RAMAN, REMA and Wang, Shunran and Ernstrom, Karin B. and Andrews, Patricia and Appleby, Brian Stephen and Bhangu, Jaspreet S. and Dhadda, Shobha and others}, title = {{Amyloid Imaging and APOE Genotype Disclosure and Short-Term Psychological Distress}}, journal = {JAMA Network Open}, year = {2026}, doi = {10.1001/jamanetworkopen.2026.3845}, pmid = {41910973}, url = {https://doi.org/10.1001/jamanetworkopen.2026.3845} } @article{govindarajan2025-40108173, author = {Govindarajan, Sindhuja Tirumalai and Mamourian, Elizabeth and Erus, Güray and Abdulkadir, Ahmed and Melhem, Randa and Doshi, Jimit J. and Pomponio, Raymond and Tosun, Duygu and others}, title = {{Machine learning reveals distinct neuroanatomical signatures of cardiovascular and metabolic diseases in cognitively unimpaired individuals}}, journal = {Nature Communications}, year = {2025}, doi = {10.1038/s41467-025-57867-7}, pmid = {40108173}, url = {https://doi.org/10.1038/s41467-025-57867-7} } @article{memel2025-40277077, author = {Memel, Molly and Staffaroni, Adam M. and Illán‐Gala, Ignacio and Castro, Jesús García and Kornak, John and Tartaglia, Carmela M. and Saloner, Rowan and VandeBunte, Anna M. and others}, title = {{Sex differences in the clinical manifestation of autosomal dominant frontotemporal dementia}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.14630}, pmid = {40277077}, url = {https://doi.org/10.1002/alz.14630} } @article{honey2026-41986736, author = {Honey, Madison I. J. and Hok-A-Hin, Yanaika Sylvana and Thijssen, Elisabeth H. and Cousins, Katheryn A Q and van der Weijden, Babette and Veld, Lisanne in ‘t and Stoops, Erik and de Boer, Sterre C.M. and others}, title = {{An acetylated Tau-174 CSF biomarker discriminates between TDP-43 and tau pathology in patients with frontotemporal lobar degeneration}}, journal = {Nature Medicine}, year = {2026}, doi = {10.1038/s41591-026-04341-6}, pmid = {41986736}, url = {https://doi.org/10.1038/s41591-026-04341-6} } @article{hajjar2022-36201209, author = {Hajjar, I. and Yang, Z. and Okafor, M. and Liu, C. and Waligorska, T. and Goldstein, F. C. and Shaw, L. M.}, title = {{Association of Plasma and Cerebrospinal Fluid Alzheimer Disease Biomarkers With Race and the Role of Genetic Ancestry, Vascular Comorbidities, and Neighborhood Factors}}, journal = {JAMA network open}, year = {2022}, doi = {10.1001/jamanetworkopen.2022.35068}, pmid = {36201209}, url = {https://doi.org/10.1001/jamanetworkopen.2022.35068} } @article{devanand2015-25471394, author = {Devanand, D. P. and Lee, S. and Manly, J. and Andrews, H. and Schupf, N. and Doty, R. L. and Stern, Y. and Zahodne, L. B. and others}, title = {{Olfactory deficits predict cognitive decline and Alzheimer dementia in an urban community}}, journal = {Neurology}, year = {2015}, doi = {10.1212/wnl.0000000000001132}, pmid = {25471394}, url = {https://doi.org/10.1212/wnl.0000000000001132} } @article{crary2014-25348064, author = {Crary, J. F. and Trojanowski, J. Q. and Schneider, J. A. and Abisambra, J. F. and Abner, E. L. and Alafuzoff, I. and Arnold, S. E. and Attems, J. and others}, title = {{Primary age-related tauopathy (PART): a common pathology associated with human aging}}, journal = {Acta neuropathologica}, year = {2014}, doi = {10.1007/s00401-014-1349-0}, pmid = {25348064}, url = {https://doi.org/10.1007/s00401-014-1349-0} } @article{simuni2024-38267190, author = {Simuni, T. and Chahine, L. M. and Poston, K. and Brumm, M. and Buracchio, T. and Campbell, M. and Chowdhury, S. and Coffey, C. and others}, title = {{A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research}}, journal = {The Lancet. Neurology}, year = {2024}, doi = {10.1016/s1474-4422(23)00405-2}, pmid = {38267190}, url = {https://doi.org/10.1016/s1474-4422(23)00405-2} } @article{galasko1998-9678311, author = {Galasko, D. and Chang, L. and Motter, R. and Clark, C. M. and Kaye, J. and Knopman, D. and Thomas, R. and Kholodenko, D. and others}, title = {{High cerebrospinal fluid tau and low amyloid beta42 levels in the clinical diagnosis of Alzheimer disease and relation to apolipoprotein E genotype}}, journal = {Archives of neurology}, year = {1998}, doi = {10.1001/archneur.55.7.937}, pmid = {9678311}, url = {https://doi.org/10.1001/archneur.55.7.937} } @article{neumann2006-17023659, author = {Neumann, M. and Sampathu, D. M. and Kwong, L. K. and Truax, A. C. and Micsenyi, M. C. and Chou, T. T. and Bruce, J. and Schuck, T. and others}, title = {{Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis}}, journal = {Science (New York, N.Y.)}, year = {2006}, doi = {10.1126/science.1134108}, pmid = {17023659}, url = {https://doi.org/10.1126/science.1134108} } @article{spinelli2017-28133816, author = {Spinelli, E. G. and Mandelli, M. L. and Miller, Z. A. and Santos-Santos, M. A. and Wilson, S. M. and Agosta, F. and Grinberg, L. T. and Huang, E. J. and others}, title = {{Typical and atypical pathology in primary progressive aphasia variants}}, journal = {Annals of neurology}, year = {2017}, doi = {10.1002/ana.24885}, pmid = {28133816}, url = {https://doi.org/10.1002/ana.24885} } @article{davatzikos2009-19416949, author = {Davatzikos, C. and Xu, F. and An, Y. and Fan, Y. and Resnick, S. M.}, title = {{Longitudinal progression of Alzheimer's-like patterns of atrophy in normal older adults: the SPARE-AD index}}, journal = {Brain : a journal of neurology}, year = {2009}, doi = {10.1093/brain/awp091}, pmid = {19416949}, url = {https://doi.org/10.1093/brain/awp091} } @article{berron2021-33725124, author = {Berron, D. and Vogel, J. W. and Insel, P. S. and Pereira, J. B. and Xie, L. and Wisse, L. E. M. and Yushkevich, P. A. and Palmqvist, S. and others}, title = {{Early stages of tau pathology and its associations with functional connectivity, atrophy and memory}}, journal = {Brain : a journal of neurology}, year = {2021}, doi = {10.1093/brain/awab114}, pmid = {33725124}, url = {https://doi.org/10.1093/brain/awab114} } @article{molinuevo2018-30488277, author = {Molinuevo, J. L. and Ayton, S. and Batrla, R. and Bednar, M. M. and Bittner, T. and Cummings, J. and Fagan, A. M. and Hampel, H. and others}, title = {{Current state of Alzheimer's fluid biomarkers}}, journal = {Acta neuropathologica}, year = {2018}, doi = {10.1007/s00401-018-1932-x}, pmid = {30488277}, url = {https://doi.org/10.1007/s00401-018-1932-x} } @article{franzmeier2020-33032659, author = {Franzmeier, N. and Suárez-Calvet, M. and Frontzkowski, L. and Moore, A. and Hohman, T. J. and Morenas-Rodriguez, E. and Nuscher, B. and Shaw, L. and others}, title = {{Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration}}, journal = {Molecular neurodegeneration}, year = {2020}, doi = {10.1186/s13024-020-00407-2}, pmid = {33032659}, url = {https://doi.org/10.1186/s13024-020-00407-2} } @article{jansen2018-29188296, author = {Jansen, W. J. and Ossenkoppele, R. and Tijms, B. M. and Fagan, A. M. and Hansson, O. and Klunk, W. E. and van der Flier, W. M. and Villemagne, V. L. and others}, title = {{Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia}}, journal = {JAMA psychiatry}, year = {2018}, doi = {10.1001/jamapsychiatry.2017.3391}, pmid = {29188296}, url = {https://doi.org/10.1001/jamapsychiatry.2017.3391} } @article{biundo2016-26852137, author = {Biundo, R. and Weis, L. and Bostantjopoulou, S. and Stefanova, E. and Falup-Pecurariu, C. and Kramberger, M. G. and Geurtsen, G. J. and Antonini, A. and others}, title = {{MMSE and MoCA in Parkinson's disease and dementia with Lewy bodies: a multicenter 1-year follow-up study}}, journal = {Journal of neural transmission (Vienna, Austria : 1996)}, year = {2016}, doi = {10.1007/s00702-016-1517-6}, pmid = {26852137}, url = {https://doi.org/10.1007/s00702-016-1517-6} } @article{jun2014-25043464, author = {Jun, G. and Asai, H. and Zeldich, E. and Drapeau, E. and Chen, C. and Chung, J. and Park, J. H. and Kim, S. and others}, title = {{PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation}}, journal = {Annals of neurology}, year = {2014}, doi = {10.1002/ana.24219}, pmid = {25043464}, url = {https://doi.org/10.1002/ana.24219} } @article{reichman2025-40544428, author = {Reichman, Trevor and Markmann, James F. and Odorico, Jon S. and Witkowski, Piotr and Fung, John J. and Wijkstrom, Martin N. and Kandeel, Fouad F and de Koning, Eelco J.P. and others}, title = {{Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes}}, journal = {New England Journal of Medicine}, year = {2025}, doi = {10.1056/nejmoa2506549}, pmid = {40544428}, url = {https://doi.org/10.1056/nejmoa2506549} } @article{nelson2012-22487856, author = {Nelson, Peter T. and Alafuzoff, Irina I. and Bigio, Eileen H. and Bouras, Constantin and Braak, Heiko and Cairns, Nigel J. and Castellani, Rudolph J. and Crain, Barbara J. and others}, title = {{Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature}}, journal = {Journal of Neuropathology \& Experimental Neurology}, year = {2012}, doi = {10.1097/nen.0b013e31825018f7}, pmid = {22487856}, url = {https://doi.org/10.1097/nen.0b013e31825018f7} } @article{fischl2002-11832223, author = {Fischl, Bruce R. and Salat, David H. and Busa, Evelina and Albert, Marilyn and Dieterich, Megan and Haselgrove, Christian and van der Kouwe, Andre J. W. and Killiany, Ronald and others}, title = {{Whole Brain Segmentation}}, journal = {Neuron}, year = {2002}, doi = {10.1016/s0896-6273(02)00569-x}, pmid = {11832223}, url = {https://doi.org/10.1016/s0896-6273(02)00569-x} } @article{doody2014-24450890, author = {Doody, Rachelle Smith and Thomas, Ronald G. and Farlow, Martin Rhys and Iwatsubo, Takeshi and Vellas, Bruno J. and Joffe, Steven and Kieburtz, Karl D. and Raman, Rema and Sun, Xiaoying and Aisen, Paul S. S. and Siemers, Eric and Liu‐Seifert, Hong and Mohs, Richard C.}, title = {{Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease}}, journal = {New England Journal of Medicine}, year = {2014}, doi = {10.1056/nejmoa1312889}, pmid = {24450890}, url = {https://doi.org/10.1056/nejmoa1312889} } @article{toledo2015-25822737, author = {Toledo, J. B. and Bjerke, M. and Da, X. and Landau, S. M. and Foster, N. L. and Jagust, W. and Jack, C. and Weiner, M. and others}, title = {{Nonlinear Association Between Cerebrospinal Fluid and Florbetapir F-18 β-Amyloid Measures Across the Spectrum of Alzheimer Disease}}, journal = {JAMA neurology}, year = {2015}, doi = {10.1001/jamaneurol.2014.4829}, pmid = {25822737}, url = {https://doi.org/10.1001/jamaneurol.2014.4829} } @article{karlawish2008-18310554, author = {Karlawish, J. and Kim, S. Y. and Knopman, D. and van Dyck, C. H. and James, B. D. and Marson, D.}, title = {{The views of Alzheimer disease patients and their study partners on proxy consent for clinical trial enrollment}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2008}, doi = {10.1097/jgp.0b013e318162992d}, pmid = {18310554}, url = {https://doi.org/10.1097/jgp.0b013e318162992d} } @article{reiman2020-32015339, author = {Reiman, E. M. and Arboleda-Velasquez, J. F. and Quiroz, Y. T. and Huentelman, M. J. and Beach, T. G. and Caselli, R. J. and Chen, Y. and Su, Y. and others}, title = {{Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study}}, journal = {Nature communications}, year = {2020}, doi = {10.1038/s41467-019-14279-8}, pmid = {32015339}, url = {https://doi.org/10.1038/s41467-019-14279-8} } @article{vemuri2009-19636049, author = {Vemuri, P. and Wiste, H. J. and Weigand, S. D. and Shaw, L. M. and Trojanowski, J. Q. and Weiner, M. W. and Knopman, D. S. and Petersen, R. C. and others}, title = {{MRI and CSF biomarkers in normal, MCI, and AD subjects: predicting future clinical change}}, journal = {Neurology}, year = {2009}, doi = {10.1212/wnl.0b013e3181af79fb}, pmid = {19636049}, url = {https://doi.org/10.1212/wnl.0b013e3181af79fb} } @article{wilson2007-17909133, author = {Wilson, R. S. and Schneider, J. A. and Arnold, S. E. and Bienias, J. L. and Bennett, D. A.}, title = {{Conscientiousness and the incidence of Alzheimer disease and mild cognitive impairment}}, journal = {Archives of general psychiatry}, year = {2007}, doi = {10.1001/archpsyc.64.10.1204}, pmid = {17909133}, url = {https://doi.org/10.1001/archpsyc.64.10.1204} } @article{russell2017-28295138, author = {Russell, D. and Diamond, E. L. and Lauder, B. and Dignam, R. R. and Dowding, D. W. and Peng, T. R. and Prigerson, H. G. and Bowles, K. H.}, title = {{Frequency and Risk Factors for Live Discharge from Hospice}}, journal = {Journal of the American Geriatrics Society}, year = {2017}, doi = {10.1111/jgs.14859}, pmid = {28295138}, url = {https://doi.org/10.1111/jgs.14859} } @article{johnson2010-21145000, author = {Johnson, J. O. and Mandrioli, J. and Benatar, M. and Abramzon, Y. and Van Deerlin, V. M. and Trojanowski, J. Q. and Gibbs, JR. and Brunetti, M. and others}, title = {{Exome sequencing reveals VCP mutations as a cause of familial ALS}}, journal = {Neuron}, year = {2010}, doi = {10.1016/j.neuron.2010.11.036}, pmid = {21145000}, url = {https://doi.org/10.1016/j.neuron.2010.11.036} } @article{bennett2006-16632311, author = {Bennett, D. A. and Schneider, J. A. and Tang, Y. and Arnold, S. E. and Wilson, R. S.}, title = {{The effect of social networks on the relation between Alzheimer's disease pathology and level of cognitive function in old people: a longitudinal cohort study}}, journal = {The Lancet. Neurology}, year = {2006}, doi = {10.1016/s1474-4422(06)70417-3}, pmid = {16632311}, url = {https://doi.org/10.1016/s1474-4422(06)70417-3} } @article{avants2008-17659998, author = {Avants, B. B. and Epstein, C. L. and Grossman, M. and Gee, J. C.}, title = {{Symmetric diffeomorphic image registration with cross-correlation: evaluating automated labeling of elderly and neurodegenerative brain}}, journal = {Medical image analysis}, year = {2008}, doi = {10.1016/j.media.2007.06.004}, pmid = {17659998}, url = {https://doi.org/10.1016/j.media.2007.06.004} } @article{vandeerlin2008-18396105, author = {Van Deerlin, V. M. and Leverenz, J. B. and Bekris, L. M. and Bird, T. D. and Yuan, W. and Elman, L. B. and Clay, D. and Wood, E. M. and others}, title = {{TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis}}, journal = {The Lancet. Neurology}, year = {2008}, doi = {10.1016/s1474-4422(08)70071-1}, pmid = {18396105}, url = {https://doi.org/10.1016/s1474-4422(08)70071-1} } @article{jaitin2019-31257031, author = {Jaitin, D. A. and Adlung, L. and Thaiss, C. A. and Weiner, A. and Li, B. and Descamps, H. and Lundgren, P. and Bleriot, C. and others}, title = {{Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner}}, journal = {Cell}, year = {2019}, doi = {10.1016/j.cell.2019.05.054}, pmid = {31257031}, url = {https://doi.org/10.1016/j.cell.2019.05.054} } @article{lleo2018-29554190, author = {Lleó, A. and Irwin, D. J. and Illán-Gala, I. and McMillan, C. T. and Wolk, D. A. and Lee, E. B. and Van Deerlin, V. M. and Shaw, L. M. and others}, title = {{A 2-Step Cerebrospinal Algorithm for the Selection of Frontotemporal Lobar Degeneration Subtypes}}, journal = {JAMA neurology}, year = {2018}, doi = {10.1001/jamaneurol.2018.0118}, pmid = {29554190}, url = {https://doi.org/10.1001/jamaneurol.2018.0118} } @article{vansteenoven2014-25381961, author = {van Steenoven, I. and Aarsland, D. and Hurtig, H. and Chen-Plotkin, A. and Duda, J. E. and Rick, J. and Chahine, L. M. and Dahodwala, N. and others}, title = {{Conversion between mini-mental state examination, montreal cognitive assessment, and dementia rating scale-2 scores in Parkinson's disease}}, journal = {Movement disorders : official journal of the Movement Disorder Society}, year = {2014}, doi = {10.1002/mds.26062}, pmid = {25381961}, url = {https://doi.org/10.1002/mds.26062} } @article{robinson2021-33449993, author = {Robinson, J. L. and Richardson, H. and Xie, S. X. and Suh, E. and Van Deerlin, V. M. and Alfaro, B. and Loh, N. and Porras-Paniagua, M. and others}, title = {{The development and convergence of co-pathologies in Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2021}, doi = {10.1093/brain/awaa438}, pmid = {33449993}, url = {https://doi.org/10.1093/brain/awaa438} } @article{toledo2013-23812319, author = {Toledo, J. B. and Korff, A. and Shaw, L. M. and Trojanowski, J. Q. and Zhang, J.}, title = {{CSF α-synuclein improves diagnostic and prognostic performance of CSF tau and Aβ in Alzheimer's disease}}, journal = {Acta neuropathologica}, year = {2013}, doi = {10.1007/s00401-013-1148-z}, pmid = {23812319}, url = {https://doi.org/10.1007/s00401-013-1148-z} } @article{brown2025-41396614, author = {Brown, Christopher Andrew and Mundada, Nidhi S. and Cousins, Katheryn A Q and Sadeghpour, Niyousha and Lyu, Xueying and McGrew, Emily and Korecka, Magdalena and Chen‐Plotkin, Alice S. and others}, title = {{Evaluation of Copathology and Clinical Trajectories in Individuals With Tau-Clinical Mismatch}}, journal = {JAMA Neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.4974}, pmid = {41396614}, url = {https://doi.org/10.1001/jamaneurol.2025.4974} } @article{rojassaunero2025-40048680, author = {Rojas‐Saunero, Liliana Paloma and Zhou, Yixuan and Hayes‐Larson, Eleanor and Wu, Yingyan and Mobley, Taylor M. and Nianogo, Roch A. and Elser, Holly C. and Gee, Gilbert C. and others}, title = {{Effect of Incident Stroke on Dementia Risk Over 10 Years in a Cohort of Asian American and Non-Latino White Older Adults in California}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000213488}, pmid = {40048680}, url = {https://doi.org/10.1212/wnl.0000000000213488} } @article{bartl2021-34618817, author = {Bartl, M. and Dakna, M. and Galasko, D. and Hutten, S. J. and Foroud, T. and Quan, M. and Marek, K. and Siderowf, A. and others}, title = {{Biomarkers of neurodegeneration and glial activation validated in Alzheimer's disease assessed in longitudinal cerebrospinal fluid samples of Parkinson's disease}}, journal = {PloS one}, year = {2021}, doi = {10.1371/journal.pone.0257372}, pmid = {34618817}, url = {https://doi.org/10.1371/journal.pone.0257372} } @article{bradley2025-40556318, author = {Bradley, J. and Pottier, C. and da Fonseca, E. L. and Kurup, J. T. and Western, D. and Wang, C. and Neupane, A. and Ray, N. R. and Jean-Francois, M. and Ali, M. and Timsina, J. and Bergmann, K. and others}, title = {{Novel early-onset Alzheimer-associated genes influence risk through dysregulation of glutamate, immune activation, and intracellular signaling pathways}}, journal = {Alzheimer's \& Dementia}, year = {2025}, doi = {10.1002/alz.70377}, pmid = {40556318}, url = {https://doi.org/10.1002/alz.70377} } @article{cousins2024-38306599, author = {Cousins, K. A. Q. and Irwin, D. J. and Tropea, T. F. and Rhodes, E. and Phillips, J. and Chen-Plotkin, A. S. and Brumm, M. C. and Coffey, C. S. and others}, title = {{Evaluation of ATNPD Framework and Biofluid Markers to Predict Cognitive Decline in Early Parkinson Disease}}, journal = {Neurology}, year = {2024}, doi = {10.1212/wnl.0000000000208033}, pmid = {38306599}, url = {https://doi.org/10.1212/wnl.0000000000208033} } @article{shrestha2025-40373252, author = {Shrestha, S. and Zhu, X. and Griswold, M. E. and Palta, P. and Sullivan, K. J. and Chen, H. and Schneider, A. L. C. and Moghekar, A. and others}, title = {{Olfaction and Plasma Biomarkers of Alzheimer Disease and Neurodegeneration in the Atherosclerosis Risk in Communities Study}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000213706}, pmid = {40373252}, url = {https://doi.org/10.1212/wnl.0000000000213706} } @article{jagust2009-19822868, author = {Jagust, W. J. and Landau, S. M. and Shaw, L. M. and Trojanowski, J. Q. and Koeppe, R. A. and Reiman, E. M. and Foster, N. L. and Petersen, R. C. and others}, title = {{Relationships between biomarkers in aging and dementia}}, journal = {Neurology}, year = {2009}, doi = {10.1212/wnl.0b013e3181bc010c}, pmid = {19822868}, url = {https://doi.org/10.1212/wnl.0b013e3181bc010c} } @article{vemuri2009-19636048, author = {Vemuri, P. and Wiste, H. J. and Weigand, S. D. and Shaw, L. M. and Trojanowski, J. Q. and Weiner, M. W. and Knopman, D. S. and Petersen, R. C. and others}, title = {{MRI and CSF biomarkers in normal, MCI, and AD subjects: diagnostic discrimination and cognitive correlations}}, journal = {Neurology}, year = {2009}, doi = {10.1212/wnl.0b013e3181af79e5}, pmid = {19636048}, url = {https://doi.org/10.1212/wnl.0b013e3181af79e5} } @article{lo2012-22972646, author = {Lo, R. Y. and Jagust, W. J. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{Vascular burden and Alzheimer disease pathologic progression}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e31826c1b9d}, pmid = {22972646}, url = {https://doi.org/10.1212/wnl.0b013e31826c1b9d} } @article{austin2022-35352569, author = {Austin, T. R. and Nasrallah, I. M. and Erus, G. and Desiderio, L. M. and Chen, L. Y. and Greenland, P. and Harding, B. N. and Hughes, T. M. and others}, title = {{Association of Brain Volumes and White Matter Injury With Race, Ethnicity, and Cardiovascular Risk Factors: The Multi-Ethnic Study of Atherosclerosis}}, journal = {Journal of the American Heart Association}, year = {2022}, doi = {10.1161/jaha.121.023159}, pmid = {35352569}, url = {https://doi.org/10.1161/jaha.121.023159} } @article{craigschapiro2010-21035623, author = {Craig-Schapiro, R. and Perrin, R. J. and Roe, C. M. and Xiong, C. and Carter, D. and Cairns, N. J. and Mintun, M. A. and Peskind, E. R. and others}, title = {{YKL-40: a novel prognostic fluid biomarker for preclinical Alzheimer's disease}}, journal = {Biological psychiatry}, year = {2010}, doi = {10.1016/j.biopsych.2010.08.025}, pmid = {21035623}, url = {https://doi.org/10.1016/j.biopsych.2010.08.025} } @article{peng2018-29743672, author = {Peng, C. and Gathagan, R. J. and Covell, D. J. and Medellin, C. and Stieber, A. and Robinson, J. L. and Zhang, B. and Pitkin, R. M. and others}, title = {{Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathies}}, journal = {Nature}, year = {2018}, doi = {10.1038/s41586-018-0104-4}, pmid = {29743672}, url = {https://doi.org/10.1038/s41586-018-0104-4} } @article{ewers2020-32790063, author = {Ewers, M. and Biechele, G. and Suárez-Calvet, M. and Sacher, C. and Blume, T. and Morenas-Rodriguez, E. and Deming, Y. and Piccio, L. and others}, title = {{Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation}}, journal = {EMBO molecular medicine}, year = {2020}, doi = {10.15252/emmm.202012308}, pmid = {32790063}, url = {https://doi.org/10.15252/emmm.202012308} } @article{staffaroni2020-33112398, author = {Staffaroni, A. M. and Goh, S. M. and Cobigo, Y. and Ong, E. and Lee, S. E. and Casaletto, K. B. and Wolf, A. and Forsberg, L. K. and others}, title = {{Rates of Brain Atrophy Across Disease Stages in Familial Frontotemporal Dementia Associated With MAPT, GRN, and C9orf72 Pathogenic Variants}}, journal = {JAMA network open}, year = {2020}, doi = {10.1001/jamanetworkopen.2020.22847}, pmid = {33112398}, url = {https://doi.org/10.1001/jamanetworkopen.2020.22847} } @article{spillantini1997-9278044, author = {Spillantini, Maria Grazia and Schmidt, Marie Luise and Lee, Virginia M.‐Y. and Trojanowski, John Q. and Jakes, Ross and Goedert, Michel}, title = {{α-Synuclein in Lewy bodies}}, journal = {Nature}, year = {1997}, doi = {10.1038/42166}, pmid = {9278044}, url = {https://doi.org/10.1038/42166} } @article{rajabli2023-36539198, author = {Rajabli, F. and Tosto, G. and Hamilton-Nelson, K. L. and Kunkle, B. W. and Vardarajan, B. N. and Naj, A. and Whitehead, P. G. and Gardner, O. K. and Bush, W. S. and Sariya, S. and Mayeux, R. P. and Farrer, L. A. and others}, title = {{Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans}}, journal = {Alzheimer's \& Dementia}, year = {2023}, doi = {10.1002/alz.12865}, pmid = {36539198}, url = {https://doi.org/10.1002/alz.12865} } @article{duggan2022-35985823, author = {Duggan, M. R. and Peng, Z. and An, Y. and Kitner Triolo, M. H. and Shafer, A. T. and Davatzikos, C. and Erus, G. and Karikkineth, A. and others}, title = {{Herpes Viruses in the Baltimore Longitudinal Study of Aging: Associations With Brain Volumes, Cognitive Performance, and Plasma Biomarkers}}, journal = {Neurology}, year = {2022}, doi = {10.1212/wnl.0000000000201036}, pmid = {35985823}, url = {https://doi.org/10.1212/wnl.0000000000201036} } @article{kim2011-21123754, author = {Kim, S. and Swaminathan, S. and Shen, L. and Risacher, S. L. and Nho, K. and Foroud, T. and Shaw, L. M. and Trojanowski, J. Q. and others}, title = {{Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort}}, journal = {Neurology}, year = {2011}, doi = {10.1212/wnl.0b013e318204a397}, pmid = {21123754}, url = {https://doi.org/10.1212/wnl.0b013e318204a397} } @article{martin2006-17068314, author = {Martin, B. K. and Frangakis, C. E. and Rosenberg, P. B. and Mintzer, J. E. and Katz, I. R. and Porsteinsson, A. P. and Schneider, L. S. and Rabins, P. V. and others}, title = {{Design of Depression in Alzheimer's Disease Study-2}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2006}, doi = {10.1097/01.jgp.0000240977.71305.ee}, pmid = {17068314}, url = {https://doi.org/10.1097/01.jgp.0000240977.71305.ee} } @article{cairns2007-17579875, author = {Cairns, N. J. and Bigio, E. H. and Mackenzie, I. R. and Neumann, M. and Lee, V. M. and Hatanpaa, K. J. and White, C. L. and Schneider, J. A. and others}, title = {{Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration}}, journal = {Acta neuropathologica}, year = {2007}, doi = {10.1007/s00401-007-0237-2}, pmid = {17579875}, url = {https://doi.org/10.1007/s00401-007-0237-2} } @article{toledo2013-23842566, author = {Toledo, J. B. and Arnold, S. E. and Raible, K. and Brettschneider, J. and Xie, S. X. and Grossman, M. and Monsell, S. E. and Kukull, W. A. and others}, title = {{Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer's Coordinating Centre}}, journal = {Brain : a journal of neurology}, year = {2013}, doi = {10.1093/brain/awt188}, pmid = {23842566}, url = {https://doi.org/10.1093/brain/awt188} } @article{rowe2008-18191617, author = {Rowe, C. C. and Ackerman, U. and Browne, W. and Mulligan, R. and Pike, K. L. and O'Keefe, G. and Tochon-Danguy, H. and Chan, G. and others}, title = {{Imaging of amyloid beta in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: proof of mechanism}}, journal = {The Lancet. Neurology}, year = {2008}, doi = {10.1016/s1474-4422(08)70001-2}, pmid = {18191617}, url = {https://doi.org/10.1016/s1474-4422(08)70001-2} } @article{wachterman2016-27367547, author = {Wachterman, M. W. and Pilver, C. and Smith, D. and Ersek, M. and Lipsitz, SR. and Keating, N. L.}, title = {{Quality of End-of-Life Care Provided to Patients With Different Serious Illnesses}}, journal = {JAMA internal medicine}, year = {2016}, doi = {10.1001/jamainternmed.2016.1200}, pmid = {27367547}, url = {https://doi.org/10.1001/jamainternmed.2016.1200} } @article{chen2021-34537810, author = {Chen, S. D. and Lu, J. Y. and Li, H. Q. and Yang, Y. X. and Jiang, J. H. and Cui, M. and Zuo, C. T. and Tan, L. and others}, title = {{Staging tau pathology with tau PET in Alzheimer's disease: a longitudinal study}}, journal = {Translational psychiatry}, year = {2021}, doi = {10.1038/s41398-021-01602-5}, pmid = {34537810}, url = {https://doi.org/10.1038/s41398-021-01602-5} } @article{aarsland2021-34210995, author = {Aarsland, D. and Batzu, L. and Halliday, G. M. and Geurtsen, G. J. and Ballard, C. and Ray Chaudhuri, K. and Weintraub, D.}, title = {{Parkinson disease-associated cognitive impairment}}, journal = {Nature reviews. Disease primers}, year = {2021}, doi = {10.1038/s41572-021-00280-3}, pmid = {34210995}, url = {https://doi.org/10.1038/s41572-021-00280-3} } @article{nakashimayasuda2007-17653732, author = {Nakashima-Yasuda, H. and Uryu, K. and Robinson, J. and Xie, S. X. and Hurtig, H. and Duda, J. E. and Arnold, S. E. and Siderowf, A. and others}, title = {{Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases}}, journal = {Acta neuropathologica}, year = {2007}, doi = {10.1007/s00401-007-0261-2}, pmid = {17653732}, url = {https://doi.org/10.1007/s00401-007-0261-2} } @article{turner1996-8967747, author = {Turner, R. S. and Kenyon, L. C. and Trojanowski, J. Q. and Gonatas, N. and Grossman, M.}, title = {{Clinical, neuroimaging, and pathologic features of progressive nonfluent aphasia}}, journal = {Annals of neurology}, year = {1996}, doi = {10.1002/ana.410390205}, pmid = {8967747}, url = {https://doi.org/10.1002/ana.410390205} } @article{fazekas1987-3496763, author = {Fazekas, F. and Chawluk, J. B. and Alavi, A. and Hurtig, H. I. and Zimmerman, R. A.}, title = {{MR signal abnormalities at 1.5 T in Alzheimer's dementia and normal aging}}, journal = {AJR. American journal of roentgenology}, year = {1987}, doi = {10.2214/ajr.149.2.351}, pmid = {3496763}, url = {https://doi.org/10.2214/ajr.149.2.351} } @article{giasson2000-11062131, author = {Giasson, B. I. and Duda, J. E. and Murray, IV. and Chen, Q. and Souza, J. M. and Hurtig, H. I. and Ischiropoulos, H. and Trojanowski, J. Q. and others}, title = {{Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions}}, journal = {Science (New York, N.Y.)}, year = {2000}, doi = {10.1126/science.290.5493.985}, pmid = {11062131}, url = {https://doi.org/10.1126/science.290.5493.985} } @article{hong1998-9836646, author = {Hong, M. and Zhukareva, V. and Vogelsberg-Ragaglia, V. and Wszolek, Z. and Reed, L. and Miller, B. I. and Geschwind, D. H. and Bird, T. D. and others}, title = {{Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17}}, journal = {Science (New York, N.Y.)}, year = {1998}, doi = {10.1126/science.282.5395.1914}, pmid = {9836646}, url = {https://doi.org/10.1126/science.282.5395.1914} } @article{cairns2007-17591968, author = {Cairns, N. J. and Neumann, M. and Bigio, E. H. and Holm, I. E. and Troost, D. and Hatanpaa, K. J. and Foong, C. and White, C. L. and others}, title = {{TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions}}, journal = {The American journal of pathology}, year = {2007}, doi = {10.2353/ajpath.2007.070182}, pmid = {17591968}, url = {https://doi.org/10.2353/ajpath.2007.070182} } @article{leyns2019-31235932, author = {Leyns, C. E. G. and Gratuze, M. and Narasimhan, S. and Jain, N. and Koscal, L. J. and Jiang, H. and Manis, M. and Colonna, M. and others}, title = {{TREM2 function impedes tau seeding in neuritic plaques}}, journal = {Nature neuroscience}, year = {2019}, doi = {10.1038/s41593-019-0433-0}, pmid = {31235932}, url = {https://doi.org/10.1038/s41593-019-0433-0} } @article{ohrfelt2023-36192174, author = {Öhrfelt, A. and Benedet, A. L. and Ashton, N. J. and Kvartsberg, H. and Vandijck, M. and Weiner, M. W. and Trojanowski, J. Q. and Shaw, L. M. and others}, title = {{Association of CSF GAP-43 With the Rate of Cognitive Decline and Progression to Dementia in Amyloid-Positive Individuals}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000201417}, pmid = {36192174}, url = {https://doi.org/10.1212/wnl.0000000000201417} } @article{williams2025-40314392, author = {Williams, Jeremy R. and DeConne, Theodore M. and Pewowaruk, Ryan J. and Korcarz, Claudia E. and Tanley, Jordan E. and Carlsson, Cynthia M. and Heckbert, Susan R. and Habes, Mohamad and others}, title = {{Total and Structural Carotid Artery Stiffness Are Associated With Cognitive Decline and Structural Brain Abnormalities Related to Alzheimer Disease and Alzheimer Disease‐Related Dementias Pathology: The Multi‐Ethnic Study of Atherosclerosis}}, journal = {Journal of the American Heart Association}, year = {2025}, doi = {10.1161/jaha.124.039925}, pmid = {40314392}, url = {https://doi.org/10.1161/jaha.124.039925} } @article{duggan2025-39936291, author = {Duggan, Michael R. and Paterson, Clare and Lü, Yifei and Biegel, Hannah and Dark, Heather E. and Cordon, Jenifer and Bilgel, Murat and Kaneko, Naoto and others}, title = {{The Dementia SomaSignal Test (dSST): A plasma proteomic predictor of 20‐year dementia risk}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.14549}, pmid = {39936291}, url = {https://doi.org/10.1002/alz.14549} } @article{morrow2025-40079430, author = {Morrow, Christopher B. and Kamath, Vidyulata J. and Dickerson, Bradford Clark and Eldaief, Mark C. and Rezaii, Neguine and Wong, Bonnie and McGinnis, Scott and Darby, Ryan and others}, title = {{Neuropsychiatric symptoms cluster and fluctuate over time in behavioral variant frontotemporal dementia}}, journal = {Psychiatry and Clinical Neurosciences}, year = {2025}, doi = {10.1111/pcn.13810}, pmid = {40079430}, url = {https://doi.org/10.1111/pcn.13810} } @article{hoglinger2017-28467028, author = {Höglinger, Günter U. and Respondek, Gesine and Stamelou, María and Kurz, Carolin and Josephs, Keith A. and Lang, Anthony E. and Mollenhauer, Brit and Müller, Ulrich and Nilsson, Christer and Whitwell, Jennifer L. and Arzberger, Thomas and Englund, Elisabet M. and Gelpí, Ellen and Giese, Armin and Irwin, David John and Meissner, Wassilios G. and Pantelyat, Alexander Y. and Rajput, Alex H. and Van Swieten, John Cornelis and Troakes, Claire and Antonini, Angelo and Bhatia, Kailash P. and Bordelon, Yvette M. and Compta, Yaroslau and Corvol, Jean‐Christophe and Colosimo, Carlo and Dickson, Dennis W. and Dodel, Richard C. and Ferguson, Leslie W. and Grossman, Murray and Kassubek, Jan and Krismer, Florian and Levin, Johannes and Lorenzl, Stefan and Morris, Huw R. and Nestor, Peter J. and Oertel, Wolfgang H. and Poewe, Werner H and Rabinovici, Gil D. and Rowe, James Benedict and Schellenberg, Gerard D. and Seppi, Klaus and van Eimeren, Thilo and Wenning, Gregor Karl and Boxer, Adam L. and Golbe, Lawrence I. and Litvan, Irene and {Movement Disorder Society–endorsed PSP Study Group}}, title = {{Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria}}, journal = {Movement Disorders}, year = {2017}, doi = {10.1002/mds.26987}, pmid = {28467028}, url = {https://doi.org/10.1002/mds.26987} } @article{mackenzie2009-19924424, author = {Mackenzie, Ian R. and Neumann, Manuela and Bigio, Eileen H. and Cairns, Nigel J. and Alafuzoff, Irina I. and Kril, Jillian J. and Kovács, Gábor Géza and Ghetti, Bernardino Francesco and Halliday, Glenda Margaret and Holm, Ida E. and Ince, Paul G. and Kamphorst, Wouter and Révész, Tamás and Rozemüller, Annemieke J.M. and Kumar‐Singh, Samir and Akiyama, Haruhiko and Baborie, Atik and Spina, Salvatore E. and Dickson, Dennis W. and Trojanowski, John Q. and Mann, David}, title = {{Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update}}, journal = {Acta Neuropathologica}, year = {2009}, doi = {10.1007/s00401-009-0612-2}, pmid = {19924424}, url = {https://doi.org/10.1007/s00401-009-0612-2} } @article{mackenzie2011-21644037, author = {Mackenzie, Ian R. and Neumann, Manuela and Baborie, Atik and Sampathu, Deepak M. and du Plessis, Daniel and Jaros, Evelyn and Perry, Robert Henry and Trojanowski, John Q. and Mann, David and Lee, Virginia M.‐Y.}, title = {{A harmonized classification system for FTLD-TDP pathology}}, journal = {Acta Neuropathologica}, year = {2011}, doi = {10.1007/s00401-011-0845-8}, pmid = {21644037}, url = {https://doi.org/10.1007/s00401-011-0845-8} } @article{stevens2007-18083105, author = {Stevens, Beth A. and Allen, Nicola J. and Vazquez, Luis E and Howell, Gareth R. and Christopherson, Karen S. and Nouri, Navid and Micheva, Kristina D. and Mehalow, Adrienne K. and Huberman, Andrew D. and Stafford, Benjamin K. and Sher, Alexander and Litke, Alan M and Lambris, John D. and Smith, Stephen J and John, Simon W. M. and Barres, Ben A.}, title = {{The Classical Complement Cascade Mediates CNS Synapse Elimination}}, journal = {Cell}, year = {2007}, doi = {10.1016/j.cell.2007.10.036}, pmid = {18083105}, url = {https://doi.org/10.1016/j.cell.2007.10.036} } @article{morrill2026-42385118, author = {Morrill, V. N. and Pike, JR. and Hu, J. and Fornage, M. and Surapaneni, A. and Walker, K. A. and Knopman, D. S. and Mosley, T. H. and Coresh, J. and Schneider, A. L. C. and others}, title = {{Genetic Risk for Alzheimer Disease, Midlife Hypertension, and Dementia: The ARIC Neurocognitive Study}}, journal = {Neurology}, year = {2026}, doi = {10.1212/WNL.0000000000218280}, pmid = {42385118}, url = {https://doi.org/10.1212/WNL.0000000000218280} } @article{flynnlongmire2014-24314887, author = {Flynn Longmire, C. V. and Drye, L. T. and Frangakis, C. E. and Martin, B. K. and Meinert, C. L. and Mintzer, J. E. and Munro, C. A. and Porsteinsson, A. P. and others}, title = {{Is sertraline treatment or depression remission in depressed Alzheimer patients associated with improved caregiver well being? Depression in Alzheimer's Disease Study 2}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2014}, doi = {10.1016/j.jagp.2013.02.014}, pmid = {24314887}, url = {https://doi.org/10.1016/j.jagp.2013.02.014} } @article{litvan2012-22275317, author = {Litvan, I. and Goldman, J. G. and Tröster, A. I. and Schmand, B. A. and Weintraub, D. and Petersen, R. C. and Mollenhauer, B. and Adler, C. H. and others}, title = {{Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines}}, journal = {Movement disorders : official journal of the Movement Disorder Society}, year = {2012}, doi = {10.1002/mds.24893}, pmid = {22275317}, url = {https://doi.org/10.1002/mds.24893} } @article{tandon2013-23800613, author = {Tandon, R. and Gaebel, W. and Barch, D. M. and Bustillo, J. and Gur, R. E. and Heckers, S. and Malaspina, D. and Owen, M. J. and others}, title = {{Definition and description of schizophrenia in the DSM-5}}, journal = {Schizophrenia research}, year = {2013}, doi = {10.1016/j.schres.2013.05.028}, pmid = {23800613}, url = {https://doi.org/10.1016/j.schres.2013.05.028} } @article{lippa2007-17353469, author = {Lippa, C. F. and Duda, J. E. and Grossman, M. and Hurtig, H. I. and Aarsland, D. and Boeve, B. F. and Brooks, D. J. and Dickson, D. W. and others}, title = {{DLB and PDD boundary issues: diagnosis, treatment, molecular pathology, and biomarkers}}, journal = {Neurology}, year = {2007}, doi = {10.1212/01.wnl.0000256715.13907.d3}, pmid = {17353469}, url = {https://doi.org/10.1212/01.wnl.0000256715.13907.d3} } @article{tracy2022-35063084, author = {Tracy, T. E. and Madero-Pérez, J. and Swaney, D. L. and Chang, T. S. and Moritz, M. and Konrad, C. and Ward, M. E. and Stevenson, E. and others}, title = {{Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration}}, journal = {Cell}, year = {2022}, doi = {10.1016/j.cell.2021.12.041}, pmid = {35063084}, url = {https://doi.org/10.1016/j.cell.2021.12.041} } @article{mattsson2015-25541191, author = {Mattsson, N. and Insel, P. S. and Donohue, M. and Landau, S. and Jagust, W. J. and Shaw, L. M. and Trojanowski, J. Q. and Zetterberg, H. and others}, title = {{Independent information from cerebrospinal fluid amyloid-β and florbetapir imaging in Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2015}, doi = {10.1093/brain/awu367}, pmid = {25541191}, url = {https://doi.org/10.1093/brain/awu367} } @article{brys2009-17889968, author = {Brys, M. and Pirraglia, E. and Rich, K. and Rolstad, S. and Mosconi, L. and Switalski, R. and Glodzik-Sobanska, L. and De Santi, S. and others}, title = {{Prediction and longitudinal study of CSF biomarkers in mild cognitive impairment}}, journal = {Neurobiology of aging}, year = {2009}, doi = {10.1016/j.neurobiolaging.2007.08.010}, pmid = {17889968}, url = {https://doi.org/10.1016/j.neurobiolaging.2007.08.010} } @article{rosenlang2026-42371653, author = {Rosen‐Lang, Yael and Vrillon, Agathe and Pasternak, Shlomit and Blazhenets, Ganna and Soleimani‐Meigooni, David N. and Rabinovici, Gil D. and Weiner, Michael W. and Hantke, Nathan C. and others}, title = {{Prior Traumatic Brain Injury and Alzheimer Disease Blood Biomarkers}}, journal = {JAMA Neurology}, year = {2026}, doi = {10.1001/jamaneurol.2026.2042}, pmid = {42371653}, url = {https://doi.org/10.1001/jamaneurol.2026.2042} } @article{yoshiyama2007-17270732, author = {Yoshiyama, Yasumasa and Higuchi, Makoto and Zhang, Bin and Huang, Shu-Ming and Iwata, Nobuhisa and Saido, Takaomi C. and Maeda, Jun and Suhara, Tetsuya and Trojanowski, John Q. and Lee, Virginia M.‐Y.}, title = {{Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model}}, journal = {Neuron}, year = {2007}, doi = {10.1016/j.neuron.2007.01.010}, pmid = {17270732}, url = {https://doi.org/10.1016/j.neuron.2007.01.010} } @article{mata2014-25178429, author = {Mata, I. F. and Leverenz, J. B. and Weintraub, D. and Trojanowski, J. Q. and Hurtig, H. I. and Van Deerlin, V. M. and Ritz, B. and Rausch, R. and others}, title = {{APOE, MAPT, and SNCA genes and cognitive performance in Parkinson disease}}, journal = {JAMA neurology}, year = {2014}, doi = {10.1001/jamaneurol.2014.1455}, pmid = {25178429}, url = {https://doi.org/10.1001/jamaneurol.2014.1455} } @article{yokoyama2016-27088644, author = {Yokoyama, J. S. and Wang, Y. and Schork, A. J. and Thompson, W. K. and Karch, C. M. and Cruchaga, C. and McEvoy, L. K. and Witoelar, A. and others}, title = {{Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease}}, journal = {JAMA neurology}, year = {2016}, doi = {10.1001/jamaneurol.2016.0150}, pmid = {27088644}, url = {https://doi.org/10.1001/jamaneurol.2016.0150} } @article{habes2016-27045845, author = {Habes, M. and Janowitz, D. and Erus, G. and Toledo, J. B. and Resnick, S. M. and Doshi, J. and Van der Auwera, S. and Wittfeld, K. and others}, title = {{Advanced brain aging: relationship with epidemiologic and genetic risk factors, and overlap with Alzheimer disease atrophy patterns}}, journal = {Translational psychiatry}, year = {2016}, doi = {10.1038/tp.2016.39}, pmid = {27045845}, url = {https://doi.org/10.1038/tp.2016.39} } @article{jack2012-22409939, author = {Jack, C. R. and Vemuri, P. and Wiste, H. J. and Weigand, S. D. and Lesnick, T. G. and Lowe, V. and Kantarci, K. and Bernstein, M. A. and others}, title = {{Shapes of the trajectories of 5 major biomarkers of Alzheimer disease}}, journal = {Archives of neurology}, year = {2012}, doi = {10.1001/archneurol.2011.3405}, pmid = {22409939}, url = {https://doi.org/10.1001/archneurol.2011.3405} } @article{alber2019-31011621, author = {Alber, J. and Alladi, S. and Bae, H. J. and Barton, D. A. and Beckett, L. A. and Bell, J. M. and Berman, S. E. and Biessels, G. J. and others}, title = {{White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2019}, doi = {10.1016/j.trci.2019.02.001}, pmid = {31011621}, url = {https://doi.org/10.1016/j.trci.2019.02.001} } @article{irwin2012-23037886, author = {Irwin, D. J. and White, M. T. and Toledo, J. B. and Xie, S. X. and Robinson, J. L. and Van Deerlin, V. and Lee, V. M. and Leverenz, J. B. and others}, title = {{Neuropathologic substrates of Parkinson disease dementia}}, journal = {Annals of neurology}, year = {2012}, doi = {10.1002/ana.23659}, pmid = {23037886}, url = {https://doi.org/10.1002/ana.23659} } @article{lee2011-21823158, author = {Lee, S. E. and Rabinovici, G. D. and Mayo, M. C. and Wilson, S. M. and Seeley, W. W. and DeArmond, S. J. and Huang, E. J. and Trojanowski, J. Q. and others}, title = {{Clinicopathological correlations in corticobasal degeneration}}, journal = {Annals of neurology}, year = {2011}, doi = {10.1002/ana.22424}, pmid = {21823158}, url = {https://doi.org/10.1002/ana.22424} } @article{clark2003-14676043, author = {Clark, C. M. and Xie, S. and Chittams, J. and Ewbank, D. and Peskind, E. and Galasko, D. and Morris, J. C. and McKeel, D. W. and others}, title = {{Cerebrospinal fluid tau and beta-amyloid: how well do these biomarkers reflect autopsy-confirmed dementia diagnoses?}}, journal = {Archives of neurology}, year = {2003}, doi = {10.1001/archneur.60.12.1696}, pmid = {14676043}, url = {https://doi.org/10.1001/archneur.60.12.1696} } @article{schonhaut2017-28980714, author = {Schonhaut, D. R. and McMillan, C. T. and Spina, S. and Dickerson, B. C. and Siderowf, A. and Devous, M. D. and Tsai, R. and Winer, J. and others}, title = {{18 F-flortaucipir tau positron emission tomography distinguishes established progressive supranuclear palsy from controls and Parkinson disease: A multicenter study}}, journal = {Annals of neurology}, year = {2017}, doi = {10.1002/ana.25060}, pmid = {28980714}, url = {https://doi.org/10.1002/ana.25060} } @article{brettschneider2014-24407427, author = {Brettschneider, J. and Del Tredici, K. and Irwin, D. J. and Grossman, M. and Robinson, J. L. and Toledo, J. B. and Fang, L. and Van Deerlin, V. M. and others}, title = {{Sequential distribution of pTDP-43 pathology in behavioral variant frontotemporal dementia (bvFTD)}}, journal = {Acta neuropathologica}, year = {2014}, doi = {10.1007/s00401-013-1238-y}, pmid = {24407427}, url = {https://doi.org/10.1007/s00401-013-1238-y} } @article{adkinsjackson2023-37074203, author = {Adkins-Jackson, P. B. and George, K. M. and Besser, L. M. and Hyun, J. and Lamar, M. and Hill-Jarrett, T. G. and Bubu, O. M. and Flatt, J. D. and others}, title = {{The structural and social determinants of Alzheimer's disease related dementias}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2023}, doi = {10.1002/alz.13027}, pmid = {37074203}, url = {https://doi.org/10.1002/alz.13027} } @article{willis2014-24336138, author = {Willis, A. W. and Schootman, M. and Kung, N. and Wang, X. Y. and Perlmutter, J. S. and Racette, B. A.}, title = {{Disparities in deep brain stimulation surgery among insured elders with Parkinson disease}}, journal = {Neurology}, year = {2014}, doi = {10.1212/wnl.0000000000000017}, pmid = {24336138}, url = {https://doi.org/10.1212/wnl.0000000000000017} } @article{coughlin2019-30549331, author = {Coughlin, D. and Xie, S. X. and Liang, M. and Williams, A. and Peterson, C. and Weintraub, D. and McMillan, C. T. and Wolk, D. A. and others}, title = {{Cognitive and Pathological Influences of Tau Pathology in Lewy Body Disorders}}, journal = {Annals of neurology}, year = {2019}, doi = {10.1002/ana.25392}, pmid = {30549331}, url = {https://doi.org/10.1002/ana.25392} } @article{perrin2011-21264269, author = {Perrin, R. J. and Craig-Schapiro, R. and Malone, J. P. and Shah, A. R. and Gilmore, P. and Davis, A. E. and Roe, C. M. and Peskind, E. R. and others}, title = {{Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease}}, journal = {PloS one}, year = {2011}, doi = {10.1371/journal.pone.0016032}, pmid = {21264269}, url = {https://doi.org/10.1371/journal.pone.0016032} } @article{fisher2019-31541187, author = {Fisher, C. K. and Smith, A. M. and Walsh, JR. and Diseases, Coalition Against Major and Abbott and {Alliance for Aging Research} and {Alzheimer’s Association} and {Alzheimer’s Foundation of America} and others}, title = {{Machine learning for comprehensive forecasting of Alzheimer's Disease progression}}, journal = {Scientific reports}, year = {2019}, doi = {10.1038/s41598-019-49656-2}, pmid = {31541187}, url = {https://doi.org/10.1038/s41598-019-49656-2} } @article{toledo2014-24602322, author = {Toledo, J. B. and Weiner, M. W. and Wolk, D. A. and Da, X. and Chen, K. and Arnold, S. E. and Jagust, W. and Jack, C. and others}, title = {{Neuronal injury biomarkers and prognosis in ADNI subjects with normal cognition}}, journal = {Acta neuropathologica communications}, year = {2014}, doi = {10.1186/2051-5960-2-26}, pmid = {24602322}, url = {https://doi.org/10.1186/2051-5960-2-26} } @article{schneider2024-39546740, author = {Schneider, Andrea L.C. and Reyes, Anny and Henegan, James A. and Kamath, Vidyulata J. and Wruck, Lisa Miller and Pike, James Russell and Gross, Alden L. and Walker, Keenan A. and others}, title = {{Evaluating Social Determinants of Health–Based Alternatives to Race-Based Cognitive Normative Models}}, journal = {Neurology}, year = {2024}, doi = {10.1212/wnl.0000000000210030}, pmid = {39546740}, url = {https://doi.org/10.1212/wnl.0000000000210030} } @article{kunkle2025-41437928, author = {Kunkle, Brian W. and Gomez, Lissette and Tosto, Giuseppe and Rodriguez, Omar Garcia and Slifer, Susan H. and Hamilton‐Nelson, Kara L. and Naj, Adam Christian and Kushch, Nicholas A. and others}, title = {{Novel sex‐specific candidate loci associated with Alzheimer disease identified through sex‐aware multi‐ancestry genome‐wide meta‐analysis}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz70855_106407}, pmid = {41437928}, url = {https://doi.org/10.1002/alz70855_106407} } @article{stulberg2025-41223343, author = {Stulberg, Eric Lee and Wu, Chaorong and Law, Connor A. and Sabayan, Behnam and Elser, Holly C. and Kumar, Amit and Zheutlin, Alexander R. and Bress, Adam Phillip and others}, title = {{Income, Race-Ethnicity, and Dementia Risk Factors in the United States}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000214402}, pmid = {41223343}, url = {https://doi.org/10.1212/wnl.0000000000214402} } @article{tanaka2026-41587040, author = {Tanaka, Hidetomo and Black, Lauren Elaine and Forrest, Shelley L. and Danics, Krisztina and Sadia, Nusrat and Khodadadi, Mozhgan and Tator, Charles and Smith, Douglas H. and others}, title = {{Spinal Cord Tau and Protein Copathologies Associated With Chronic Traumatic Encephalopathy}}, journal = {JAMA Neurology}, year = {2026}, doi = {10.1001/jamaneurol.2025.5421}, pmid = {41587040}, url = {https://doi.org/10.1001/jamaneurol.2025.5421} } @article{sedaghat2025-40813726, author = {Sedaghat, Sanaz and Park, Saeun and Walker, Rob F. and Wang, Shuo and Liu, Jialing and Hughes, Timothy M. and Sabayan, Behnam and Tang, Weihong and others}, title = {{Proteomics-based aging clocks in midlife or late-life and their associated risk of dementia}}, journal = {Communications Medicine}, year = {2025}, doi = {10.1038/s43856-025-01096-y}, pmid = {40813726}, url = {https://doi.org/10.1038/s43856-025-01096-y} } @article{dehavenon2025-41267647, author = {de Havenon, Adam and Littig, Lauren and Clocchiatti‐Tuozzo, Santiago and Johnson, Ian P and Constantinescu, Sofia and Rivier, Cyprien A. and Huo, Shufan and Kimberly, William Taylor and others}, title = {{Additive Effects of White Matter Hyperintensity and APOE ε4 Status on Risk of Incident Dementia in Two Large Longitudinal Cohorts}}, journal = {Annals of Neurology}, year = {2025}, doi = {10.1002/ana.78103}, pmid = {41267647}, url = {https://doi.org/10.1002/ana.78103} } @article{cruchaga2013-23562540, author = {Cruchaga, Carlos C and Kauwe, John S. K. and Harari, Oscar and Jin, Sheng Chih and Cai, Yefei and Karch, Celeste M M. and Benítez, Bruno A. and Jeng, Amanda T. and Skorupa, Tara and Carrell, David and Bertelsen, Sarah E. and Bailey, Matthew H. and McKean, David M. and Shulman, Joshua M and De Jager, Philip L. and Chibnik, Lori Beth and Bennett, David and Arnold, S. E. and Harold, Denise H. and Sims, Rebecca and Gerrish, Amy and Williams, Julie H. and Van Deerlin, Vivianna M. and Lee, Virginia M.‐Y. and Shaw, Leslie M. and Trojanowski, John Q. and Haines, Jonathan L. and Mayeux, Richard P and Pericak‐Vance, Margaret A. and Farrer, Lindsay A. and Schellenberg, Gerard D. and Peskind, Elaine R. and Galasko, Douglas R and Fagan, Anne M. and Holtzman, David M. and Morris, John C. and Goate, Alison}, title = {{GWAS of Cerebrospinal Fluid Tau Levels Identifies Risk Variants for Alzheimer’s Disease}}, journal = {Neuron}, year = {2013}, doi = {10.1016/j.neuron.2013.02.026}, pmid = {23562540}, url = {https://doi.org/10.1016/j.neuron.2013.02.026} } @article{nguyen2020-32840654, author = {Nguyen, A. T. and Wang, K. and Hu, G. and Wang, X. and Miao, Z. and Azevedo, J. A. and Suh, E. and Van Deerlin, V. M. and others}, title = {{APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer's disease}}, journal = {Acta neuropathologica}, year = {2020}, doi = {10.1007/s00401-020-02200-3}, pmid = {32840654}, url = {https://doi.org/10.1007/s00401-020-02200-3} } @article{kurniansyah2026-42661068, author = {Kurniansyah, N. and Tasaki, S. and Rehman, H. and Zhu, C. and Farrell, J. and Sherva, R. and Hauger, R. and Merritt, V. C. and Panizzon, M. and Zhang, R. and Gaziano, J. M. and Gim, J. and others}, title = {{A multiancestry polygenic risk score for Alzheimer's disease is associated with cognitive decline and neuropathological hallmarks in diverse populations}}, journal = {Nature genetics}, year = {2026}, doi = {10.1038/s41588-026-02722-8}, pmid = {42661068}, url = {https://doi.org/10.1038/s41588-026-02722-8} } @article{morris2022-35580594, author = {Morris, J. C. and Weiner, M. and Xiong, C. and Beckett, L. and Coble, D. and Saito, N. and Aisen, P. S. and Allegri, R. and others}, title = {{Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology}}, journal = {Brain : a journal of neurology}, year = {2022}, doi = {10.1093/brain/awac181}, pmid = {35580594}, url = {https://doi.org/10.1093/brain/awac181} } @article{desikan2017-28323831, author = {Desikan, R. S. and Fan, C. C. and Wang, Y. and Schork, A. J. and Cabral, H. J. and Cupples, L. A. and Thompson, W. K. and Besser, L. and others}, title = {{Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score}}, journal = {PLoS medicine}, year = {2017}, doi = {10.1371/journal.pmed.1002258}, pmid = {28323831}, url = {https://doi.org/10.1371/journal.pmed.1002258} } @article{grill2024-38585443, author = {Grill, J. D. and Raman, R. and Ernstrom, K. and Wang, S. and Donohue, M. C. and Aisen, P. S. and Karlawish, J. and Henley, D. and others}, title = {{Immediate Reactions to Alzheimer Biomarker Disclosure in Cognitively Unimpaired Individuals in a Global Truncated Randomized Trial}}, journal = {Neurology. Clinical practice}, year = {2024}, doi = {10.1212/cpj.0000000000200265}, pmid = {38585443}, url = {https://doi.org/10.1212/cpj.0000000000200265} } @article{sperling2014-24648338, author = {Sperling, R. A. and Rentz, D. M. and Johnson, K. A. and Karlawish, J. and Donohue, M. and Salmon, D. P. and Aisen, P.}, title = {{The A4 study: stopping AD before symptoms begin?}}, journal = {Science translational medicine}, year = {2014}, doi = {10.1126/scitranslmed.3007941}, pmid = {24648338}, url = {https://doi.org/10.1126/scitranslmed.3007941} } @article{li2019-31201098, author = {Li, H. and Habes, M. and Wolk, D. A. and Fan, Y.}, title = {{A deep learning model for early prediction of Alzheimer's disease dementia based on hippocampal magnetic resonance imaging data}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2019}, doi = {10.1016/j.jalz.2019.02.007}, pmid = {31201098}, url = {https://doi.org/10.1016/j.jalz.2019.02.007} } @article{hurtig2000-10822429, author = {Hurtig, H. I. and Trojanowski, J. Q. and Galvin, J. and Ewbank, D. and Schmidt, M. L. and Lee, V. M. and Clark, C. M. and Glosser, G. and others}, title = {{Alpha-synuclein cortical Lewy bodies correlate with dementia in Parkinson's disease}}, journal = {Neurology}, year = {2000}, doi = {10.1212/wnl.54.10.1916}, pmid = {10822429}, url = {https://doi.org/10.1212/wnl.54.10.1916} } @article{fleisher2013-22633529, author = {Fleisher, A. S. and Chen, K. and Liu, X. and Ayutyanont, N. and Roontiva, A. and Thiyyagura, P. and Protas, H. and Joshi, A. D. and others}, title = {{Apolipoprotein E ε4 and age effects on florbetapir positron emission tomography in healthy aging and Alzheimer disease}}, journal = {Neurobiology of aging}, year = {2013}, doi = {10.1016/j.neurobiolaging.2012.04.017}, pmid = {22633529}, url = {https://doi.org/10.1016/j.neurobiolaging.2012.04.017} } @article{fagan2011-21555603, author = {Fagan, A. M. and Shaw, L. M. and Xiong, C. and Vanderstichele, H. and Mintun, M. A. and Trojanowski, J. Q. and Coart, E. and Morris, J. C. and others}, title = {{Comparison of analytical platforms for cerebrospinal fluid measures of β-amyloid 1-42, total tau, and p-tau181 for identifying Alzheimer disease amyloid plaque pathology}}, journal = {Archives of neurology}, year = {2011}, doi = {10.1001/archneurol.2011.105}, pmid = {21555603}, url = {https://doi.org/10.1001/archneurol.2011.105} } @article{wilson2007-17012338, author = {Wilson, R. S. and Arnold, S. E. and Schneider, J. A. and Tang, Y. and Bennett, D. A.}, title = {{The relationship between cerebral Alzheimer's disease pathology and odour identification in old age}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2007}, doi = {10.1136/jnnp.2006.099721}, pmid = {17012338}, url = {https://doi.org/10.1136/jnnp.2006.099721} } @article{robinson2023-36864661, author = {Robinson, J. L. and Xie, S. X. and Baer, D. R. and Suh, E. and Van Deerlin, V. M. and Loh, N. J. and Irwin, D. J. and McMillan, C. T. and others}, title = {{Pathological combinations in neurodegenerative disease are heterogeneous and disease-associated}}, journal = {Brain : a journal of neurology}, year = {2023}, doi = {10.1093/brain/awad059}, pmid = {36864661}, url = {https://doi.org/10.1093/brain/awad059} } @article{volpicellidaley2011-21982369, author = {Volpicelli-Daley, L. A. and Luk, K. C. and Patel, T. P. and Tanik, S. A. and Riddle, D. M. and Stieber, A. and Meaney, D. F. and Trojanowski, J. Q. and others}, title = {{Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death}}, journal = {Neuron}, year = {2011}, doi = {10.1016/j.neuron.2011.08.033}, pmid = {21982369}, url = {https://doi.org/10.1016/j.neuron.2011.08.033} } @article{gassetrosa2019-30853299, author = {Gasset-Rosa, F. and Lu, S. and Yu, H. and Chen, C. and Melamed, Z. and Guo, L. and Shorter, J. and Da Cruz, S. and others}, title = {{Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death}}, journal = {Neuron}, year = {2019}, doi = {10.1016/j.neuron.2019.02.038}, pmid = {30853299}, url = {https://doi.org/10.1016/j.neuron.2019.02.038} } @article{toledo2017-28341160, author = {Toledo, J. B. and Arnold, M. and Kastenmüller, G. and Chang, R. and Baillie, R. A. and Han, X. and Thambisetty, M. and Tenenbaum, J. D. and others}, title = {{Metabolic network failures in Alzheimer's disease: A biochemical road map}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2017}, doi = {10.1016/j.jalz.2017.01.020}, pmid = {28341160}, url = {https://doi.org/10.1016/j.jalz.2017.01.020} } @article{rathore2017-28414186, author = {Rathore, S. and Habes, M. and Iftikhar, M. A. and Shacklett, A. and Davatzikos, C.}, title = {{A review on neuroimaging-based classification studies and associated feature extraction methods for Alzheimer's disease and its prodromal stages}}, journal = {NeuroImage}, year = {2017}, doi = {10.1016/j.neuroimage.2017.03.057}, pmid = {28414186}, url = {https://doi.org/10.1016/j.neuroimage.2017.03.057} } @article{liu2020-31837471, author = {Liu, M. and Li, F. and Yan, H. and Wang, K. and Ma, Y. and {Alzheimer’s Disease Neuroimaging Initiative} and Shen, L. and Xu, M.}, title = {{A multi-model deep convolutional neural network for automatic hippocampus segmentation and classification in Alzheimer's disease}}, journal = {NeuroImage}, year = {2020}, doi = {10.1016/j.neuroimage.2019.116459}, pmid = {31837471}, url = {https://doi.org/10.1016/j.neuroimage.2019.116459} } @article{kunkle2017-28738127, author = {Kunkle, B. W. and Vardarajan, B. N. and Naj, A. C. and Whitehead, P. L. and Rolati, S. and Slifer, S. and Carney, R. M. and Cuccaro, M. L. and others}, title = {{Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport}}, journal = {JAMA neurology}, year = {2017}, doi = {10.1001/jamaneurol.2017.1518}, pmid = {28738127}, url = {https://doi.org/10.1001/jamaneurol.2017.1518} } @article{schindler2019-30846386, author = {Schindler, S. E. and Li, Y. and Todd, K. W. and Herries, E. M. and Henson, R. L. and Gray, J. D. and Wang, G. and Graham, D. L. and others}, title = {{Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2019}, doi = {10.1016/j.jalz.2018.12.019}, pmid = {30846386}, url = {https://doi.org/10.1016/j.jalz.2018.12.019} } @article{mata2016-26296077, author = {Mata, I. F. and Leverenz, J. B. and Weintraub, D. and Trojanowski, J. Q. and Chen-Plotkin, A. and Van Deerlin, V. M. and Ritz, B. and Rausch, R. and others}, title = {{GBA Variants are associated with a distinct pattern of cognitive deficits in Parkinson's disease}}, journal = {Movement disorders : official journal of the Movement Disorder Society}, year = {2016}, doi = {10.1002/mds.26359}, pmid = {26296077}, url = {https://doi.org/10.1002/mds.26359} } @article{rascovsky2005-16087904, author = {Rascovsky, K. and Salmon, D. P. and Lipton, A. M. and Leverenz, J. B. and DeCarli, C. and Jagust, W. J. and Clark, C. M. and Mendez, M. F. and others}, title = {{Rate of progression differs in frontotemporal dementia and Alzheimer disease}}, journal = {Neurology}, year = {2005}, doi = {10.1212/01.wnl.0000171343.43314.6e}, pmid = {16087904}, url = {https://doi.org/10.1212/01.wnl.0000171343.43314.6e} } @article{tosun2024-38770829, author = {Tosun, D. and Hausle, Z. and Iwaki, H. and Thropp, P. and Lamoureux, J. and Lee, E. B. and MacLeod, K. and McEvoy, S. and others}, title = {{A cross-sectional study of α-synuclein seed amplification assay in Alzheimer's disease neuroimaging initiative: Prevalence and associations with Alzheimer's disease biomarkers and cognitive function}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.13858}, pmid = {38770829}, url = {https://doi.org/10.1002/alz.13858} } @article{wong2010-20501908, author = {Wong, D. F. and Rosenberg, P. B. and Zhou, Y. and Kumar, A. and Raymont, V. and Ravert, H. T. and Dannals, R. F. and Nandi, A. and others}, title = {{In vivo imaging of amyloid deposition in Alzheimer disease using the radioligand 18F-AV-45 (florbetapir [corrected] F 18)}}, journal = {Journal of nuclear medicine : official publication, Society of Nuclear Medicine}, year = {2010}, doi = {10.2967/jnumed.109.069088}, pmid = {20501908}, url = {https://doi.org/10.2967/jnumed.109.069088} } @article{roy2020-31917687, author = {Roy, E. R. and Wang, B. and Wan, Y. W. and Chiu, G. and Cole, A. and Yin, Z. and Propson, N. E. and Xu, Y. and others}, title = {{Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease}}, journal = {The Journal of clinical investigation}, year = {2020}, doi = {10.1172/jci133737}, pmid = {31917687}, url = {https://doi.org/10.1172/jci133737} } @article{kosar2023-36753276, author = {Kosar, Cyrus M. and Mor, Vincent and Werner, Rachel M. and Rahman, Momotazur}, title = {{Risk of Discharge to Lower-Quality Nursing Homes Among Hospitalized Older Adults With Alzheimer Disease and Related Dementias}}, journal = {JAMA Network Open}, year = {2023}, doi = {10.1001/jamanetworkopen.2022.55134}, pmid = {36753276}, url = {https://doi.org/10.1001/jamanetworkopen.2022.55134} } @article{gribsholt2025-40766301, author = {Gribsholt, Sigrid Bjerge and Horváth–Puhó, Erzsébet and Elser, Holly C. and Laugesen, Kristina and Skajaa, Nils and Fuglsang, Cecilia Hvitfeldt and Henderson, Victor W. and Sørensen, Henrik Toft}, title = {{Obstructive sleep apnoea and risk of dementia: a Danish population-based cohort study}}, journal = {BMJ Neurology Open}, year = {2025}, doi = {10.1136/bmjno-2025-001174}, pmid = {40766301}, url = {https://doi.org/10.1136/bmjno-2025-001174} } @article{pham2025-40961986, author = {Pham, Kenneth and Salowe, Rebecca and Di Rosa, Isabel and Hamedani, Ali G. and Ying, Gui‐Shuang and O’Brien, Joan M.}, title = {{The Association between Glaucoma and Dementia in a National Cohort of All of Us Participants}}, journal = {Ophthalmology}, year = {2025}, doi = {10.1016/j.ophtha.2025.09.007}, pmid = {40961986}, url = {https://doi.org/10.1016/j.ophtha.2025.09.007} } @article{brycesmith2025-41120751, author = {Bryce-Smith, Sam and Brown, Anna‐Leigh and Chien, Max Z. Y. J. and Dattilo, Dario and Mehta, Puja R. and Mattedi, Francesca and Barattucci, Simone and Mikheenko, Alla and others}, title = {{TDP-43 loss induces cryptic polyadenylation in ALS/FTD}}, journal = {Nature Neuroscience}, year = {2025}, doi = {10.1038/s41593-025-02050-w}, pmid = {41120751}, url = {https://doi.org/10.1038/s41593-025-02050-w} } @article{johnson2013-23360977, author = {Johnson, K. A. and Minoshima, S. and Bohnen, N. I. and Donohoe, K. J. and Foster, N. L. and Herscovitch, P. and Karlawish, J. H. and Rowe, C. C. and others}, title = {{Appropriate use criteria for amyloid PET: a report of the Amyloid Imaging Task Force, the Society of Nuclear Medicine and Molecular Imaging, and the Alzheimer's Association}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2013}, doi = {10.1016/j.jalz.2013.01.002}, pmid = {23360977}, url = {https://doi.org/10.1016/j.jalz.2013.01.002} } @article{karger2024-38861647, author = {Karger, A. B. and Nasrallah, I. M. and Braffett, B. H. and Luchsinger, J. A. and Ryan, C. M. and Bebu, I. and Arends, V. and Habes, M. and others}, title = {{Plasma Biomarkers of Brain Injury and Their Association With Brain MRI and Cognition in Type 1 Diabetes}}, journal = {Diabetes care}, year = {2024}, doi = {10.2337/dc24-0229}, pmid = {38861647}, url = {https://doi.org/10.2337/dc24-0229} } @article{vemuri2010-20373342, author = {Vemuri, P. and Wiste, H. J. and Weigand, S. D. and Knopman, D. S. and Shaw, L. M. and Trojanowski, J. Q. and Aisen, P. S. and Weiner, M. and others}, title = {{Effect of apolipoprotein E on biomarkers of amyloid load and neuronal pathology in Alzheimer disease}}, journal = {Annals of neurology}, year = {2010}, doi = {10.1002/ana.21953}, pmid = {20373342}, url = {https://doi.org/10.1002/ana.21953} } @article{vemuri2010-20625167, author = {Vemuri, P. and Wiste, H. J. and Weigand, S. D. and Knopman, D. S. and Trojanowski, J. Q. and Shaw, L. M. and Bernstein, M. A. and Aisen, P. S. and others}, title = {{Serial MRI and CSF biomarkers in normal aging, MCI, and AD}}, journal = {Neurology}, year = {2010}, doi = {10.1212/wnl.0b013e3181e7ca82}, pmid = {20625167}, url = {https://doi.org/10.1212/wnl.0b013e3181e7ca82} } @article{li2010-20533968, author = {Li, G. and Shofer, J. B. and Rhew, I. C. and Kukull, W. A. and Peskind, E. R. and McCormick, W. and Bowen, J. D. and Schellenberg, G. D. and others}, title = {{Age-varying association between statin use and incident Alzheimer's disease}}, journal = {Journal of the American Geriatrics Society}, year = {2010}, doi = {10.1111/j.1532-5415.2010.02906.x}, pmid = {20533968}, url = {https://doi.org/10.1111/j.1532-5415.2010.02906.x} } @article{leoutsakos2018-29914028, author = {Leoutsakos, J. S. and Yan, H. and Anderson, W. S. and Asaad, W. F. and Baltuch, G. and Burke, A. and Chakravarty, M. M. and Drake, K. E. and others}, title = {{Deep Brain Stimulation Targeting the Fornix for Mild Alzheimer Dementia (the ADvance Trial): A Two Year Follow-up Including Results of Delayed Activation}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2018}, doi = {10.3233/jad-180121}, pmid = {29914028}, url = {https://doi.org/10.3233/jad-180121} } @article{mielke2022-35394117, author = {Mielke, M. M. and Aggarwal, N. T. and Vila-Castelar, C. and Agarwal, P. and Arenaza-Urquijo, E. M. and Brett, B. and Brugulat-Serrat, A. and DuBose, L. E. and others}, title = {{Consideration of sex and gender in Alzheimer's disease and related disorders from a global perspective}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2022}, doi = {10.1002/alz.12662}, pmid = {35394117}, url = {https://doi.org/10.1002/alz.12662} } @article{forman2006-16718704, author = {Forman, M. S. and Farmer, J. and Johnson, J. K. and Clark, C. M. and Arnold, S. E. and Coslett, H. B. and Chatterjee, A. and Hurtig, H. I. and others}, title = {{Frontotemporal dementia: clinicopathological correlations}}, journal = {Annals of neurology}, year = {2006}, doi = {10.1002/ana.20873}, pmid = {16718704}, url = {https://doi.org/10.1002/ana.20873} } @article{gupta2019-31680923, author = {Gupta, Y. and Lama, R. K. and Kwon, G. R. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{Prediction and Classification of Alzheimer's Disease Based on Combined Features From Apolipoprotein-E Genotype, Cerebrospinal Fluid, MR, and FDG-PET Imaging Biomarkers}}, journal = {Frontiers in computational neuroscience}, year = {2019}, doi = {10.3389/fncom.2019.00072}, pmid = {31680923}, url = {https://doi.org/10.3389/fncom.2019.00072} } @article{ash2019-31075725, author = {Ash, S. and Nevler, N. and Phillips, J. and Irwin, D. J. and McMillan, C. T. and Rascovsky, K. and Grossman, M.}, title = {{A longitudinal study of speech production in primary progressive aphasia and behavioral variant frontotemporal dementia}}, journal = {Brain and language}, year = {2019}, doi = {10.1016/j.bandl.2019.04.006}, pmid = {31075725}, url = {https://doi.org/10.1016/j.bandl.2019.04.006} } @article{weiner2017-27931796, author = {Weiner, M. W. and Veitch, D. P. and Aisen, P. S. and Beckett, L. A. and Cairns, N. J. and Green, R. C. and Harvey, D. and Jack, C. R. and others}, title = {{The Alzheimer's Disease Neuroimaging Initiative 3: Continued innovation for clinical trial improvement}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2017}, doi = {10.1016/j.jalz.2016.10.006}, pmid = {27931796}, url = {https://doi.org/10.1016/j.jalz.2016.10.006} } @article{bashore2024-38385291, author = {Bashore, A. C. and Yan, H. and Xue, C. and Zhu, L. Y. and Kim, E. and Mawson, T. and Coronel, J. and Chung, A. and others}, title = {{High-Dimensional Single-Cell Multimodal Landscape of Human Carotid Atherosclerosis}}, journal = {Arteriosclerosis, thrombosis, and vascular biology}, year = {2024}, doi = {10.1161/atvbaha.123.320524}, pmid = {38385291}, url = {https://doi.org/10.1161/atvbaha.123.320524} } @article{patel2019-30924900, author = {Patel, D. and Mez, J. and Vardarajan, B. N. and Staley, L. and Chung, J. and Zhang, X. and Farrell, J. J. and Rynkiewicz, M. J. and others}, title = {{Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry}}, journal = {JAMA network open}, year = {2019}, doi = {10.1001/jamanetworkopen.2019.1350}, pmid = {30924900}, url = {https://doi.org/10.1001/jamanetworkopen.2019.1350} } @article{cho2022-35487701, author = {Cho, S. and Cousins, K. A. Q. and Shellikeri, S. and Ash, S. and Irwin, D. J. and Liberman, M. Y. and Grossman, M. and Nevler, N.}, title = {{Lexical and Acoustic Speech Features Relating to Alzheimer Disease Pathology}}, journal = {Neurology}, year = {2022}, doi = {10.1212/wnl.0000000000200581}, pmid = {35487701}, url = {https://doi.org/10.1212/wnl.0000000000200581} } @article{toledo2013-23812320, author = {Toledo, J. B. and Xie, S. X. and Trojanowski, J. Q. and Shaw, L. M.}, title = {{Longitudinal change in CSF Tau and Aβ biomarkers for up to 48 months in ADNI}}, journal = {Acta neuropathologica}, year = {2013}, doi = {10.1007/s00401-013-1151-4}, pmid = {23812320}, url = {https://doi.org/10.1007/s00401-013-1151-4} } @article{kim2024-38400524, author = {Kim, Bo-Ram and Yannatos, Isabel and Blam, Kaitlin and Wiebe, Douglas J. and Xie, Sharon Xiangwen and McMillan, Corey T. and Mechanic-Hamilton, Dawn J. and Wolk, David A. and others}, title = {{Neighborhood disadvantage reduces cognitive reserve independent of neuropathologic change}}, journal = {Alzheimer s \& Dementia}, year = {2024}, doi = {10.1002/alz.13736}, pmid = {38400524}, url = {https://doi.org/10.1002/alz.13736} } @article{hokahin2025-40866991, author = {Hok-A-Hin, Yanaika Sylvana and Vermunt, Lisa and Peeters, Carel F.W. and van der Ende, Emma Louise and de Boer, Sterre C.M. and Meeter, Lieke H. H. and De Houwer, Julie F. H. and Seelaar, Harro and others}, title = {{Large-scale CSF proteome profiling identifies biomarkers for accurate diagnosis of frontotemporal dementia}}, journal = {Molecular Neurodegeneration}, year = {2025}, doi = {10.1186/s13024-025-00882-5}, pmid = {40866991}, url = {https://doi.org/10.1186/s13024-025-00882-5} } @article{derington2025-39945185, author = {Derington, Catherine G. and Berchie, Ransmond O. and Scharfstein, Daniel O. and Andrews, Ryan M. and Greene, Tom and Xu, Yizhe and King, Jordan B. and Supiano, Mark A. and others}, title = {{Effect of Initiation and Continuous Adherence to ARBs Versus ACEIs on Risk of Adjudicated Mild Cognitive Impairment or Dementia}}, journal = {The Journals of Gerontology Series A}, year = {2025}, doi = {10.1093/gerona/glaf028}, pmid = {39945185}, url = {https://doi.org/10.1093/gerona/glaf028} } @article{rezaii2025-41195302, author = {Rezaii, Neguine and Wong, Bonnie and Aisen, Paul and Beckett, Laurel A. and Dage, Jeffrey L. and Eloyan, Ani and Foroud, Tatiana M. and Womack, Kyle B. and others}, title = {{Voiceprints of cognitive impairment: analyzing digital voice for early detection of Alzheimer’s and related dementias}}, journal = {npj Dementia}, year = {2025}, doi = {10.1038/s44400-025-00040-0}, pmid = {41195302}, url = {https://doi.org/10.1038/s44400-025-00040-0} } @article{parrabravo2024-38582079, author = {Parra Bravo, C. and Giani, A. M. and Madero-Perez, J. and Zhao, Z. and Wan, Y. and Samelson, A. J. and Wong, M. Y. and Evangelisti, A. and Cordes, E. and Fan, L. and Ye, P. and Zhu, D. and others}, title = {{Human iPSC 4R tauopathy model uncovers modifiers of tau propagation}}, journal = {Cell}, year = {2024}, doi = {10.1016/j.cell.2024.03.015}, pmid = {38582079}, url = {https://doi.org/10.1016/j.cell.2024.03.015} } @article{cukier2016-27231719, author = {Cukier, H. N. and Kunkle, B. W. and Vardarajan, B. N. and Rolati, S. and Hamilton-Nelson, K. L. and Kohli, M. A. and Whitehead, P. L. and Dombroski, B. A. and others}, title = {{ABCA7 frameshift deletion associated with Alzheimer disease in African Americans}}, journal = {Neurology. Genetics}, year = {2016}, doi = {10.1212/nxg.0000000000000079}, pmid = {27231719}, url = {https://doi.org/10.1212/nxg.0000000000000079} } @article{barral2012-22539578, author = {Barral, S. and Bird, T. and Goate, A. and Farlow, M. R. and Diaz-Arrastia, R. and Bennett, D. A. and Graff-Radford, N. and Boeve, B. F. and others}, title = {{Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e3182553c48}, pmid = {22539578}, url = {https://doi.org/10.1212/wnl.0b013e3182553c48} } @article{peters2016-26303700, author = {Peters, M. E. and Vaidya, V. and Drye, L. T. and Devanand, D. P. and Mintzer, J. E. and Pollock, B. G. and Porsteinsson, A. P. and Rosenberg, P. B. and others}, title = {{Citalopram for the Treatment of Agitation in Alzheimer Dementia: Genetic Influences}}, journal = {Journal of geriatric psychiatry and neurology}, year = {2016}, doi = {10.1177/0891988715601735}, pmid = {26303700}, url = {https://doi.org/10.1177/0891988715601735} } @article{irwin2013-23900411, author = {Irwin, D. J. and Lee, V. M. and Trojanowski, J. Q.}, title = {{Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies}}, journal = {Nature reviews. Neuroscience}, year = {2013}, doi = {10.1038/nrn3549}, pmid = {23900411}, url = {https://doi.org/10.1038/nrn3549} } @article{hu2010-20819999, author = {Hu, W. T. and Wang, Z. and Lee, V. M. and Trojanowski, J. Q. and Detre, J. A. and Grossman, M.}, title = {{Distinct cerebral perfusion patterns in FTLD and AD}}, journal = {Neurology}, year = {2010}, doi = {10.1212/wnl.0b013e3181f11e35}, pmid = {20819999}, url = {https://doi.org/10.1212/wnl.0b013e3181f11e35} } @article{baumgarten2004-15271116, author = {Baumgarten, M. and Margolis, D. and van Doorn, C. and Gruber-Baldini, A. L. and Hebel, JR. and Zimmerman, S. and Magaziner, J.}, title = {{Black/White differences in pressure ulcer incidence in nursing home residents}}, journal = {Journal of the American Geriatrics Society}, year = {2004}, doi = {10.1111/j.1532-5415.2004.52358.x}, pmid = {15271116}, url = {https://doi.org/10.1111/j.1532-5415.2004.52358.x} } @article{gitler2009-19182805, author = {Gitler, A. D. and Chesi, A. and Geddie, M. L. and Strathearn, K. E. and Hamamichi, S. and Hill, K. J. and Caldwell, K. A. and Caldwell, G. A. and others}, title = {{Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity}}, journal = {Nature genetics}, year = {2009}, doi = {10.1038/ng.300}, pmid = {19182805}, url = {https://doi.org/10.1038/ng.300} } @article{lee2001-11520930, author = {Lee, V. M. and Goedert, M. and Trojanowski, J. Q.}, title = {{Neurodegenerative tauopathies}}, journal = {Annual review of neuroscience}, year = {2001}, doi = {10.1146/annurev.neuro.24.1.1121}, pmid = {11520930}, url = {https://doi.org/10.1146/annurev.neuro.24.1.1121} } @article{volpicellidaley2014-25122523, author = {Volpicelli-Daley, L. A. and Luk, K. C. and Lee, V. M.}, title = {{Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite-like aggregates}}, journal = {Nature protocols}, year = {2014}, doi = {10.1038/nprot.2014.143}, pmid = {25122523}, url = {https://doi.org/10.1038/nprot.2014.143} } @article{cohen2015-25556531, author = {Cohen, T. J. and Hwang, A. W. and Restrepo, C. R. and Yuan, C. X. and Trojanowski, J. Q. and Lee, V. M.}, title = {{An acetylation switch controls TDP-43 function and aggregation propensity}}, journal = {Nature communications}, year = {2015}, doi = {10.1038/ncomms6845}, pmid = {25556531}, url = {https://doi.org/10.1038/ncomms6845} } @article{weiner2010-20451868, author = {Weiner, M. W. and Aisen, P. S. and Jack, C. R. and Jagust, W. J. and Trojanowski, J. Q. and Shaw, L. and Saykin, A. J. and Morris, J. C. and others}, title = {{The Alzheimer's disease neuroimaging initiative: progress report and future plans}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2010}, doi = {10.1016/j.jalz.2010.03.007}, pmid = {20451868}, url = {https://doi.org/10.1016/j.jalz.2010.03.007} } @article{benatar2022-34677606, author = {Benatar, M. and Wuu, J. and McHutchison, C. and Postuma, R. B. and Boeve, B. F. and Petersen, R. and Ross, C. A. and Rosen, H. and others}, title = {{Preventing amyotrophic lateral sclerosis: insights from pre-symptomatic neurodegenerative diseases}}, journal = {Brain : a journal of neurology}, year = {2022}, doi = {10.1093/brain/awab404}, pmid = {34677606}, url = {https://doi.org/10.1093/brain/awab404} } @article{ramakers2013-22954311, author = {Ramakers, I. H. and Verhey, F. R. and Scheltens, P. and Hampel, H. and Soininen, H. and Aalten, P. and Rikkert, M. O. and Verbeek, M. M. and others}, title = {{Anxiety is related to Alzheimer cerebrospinal fluid markers in subjects with mild cognitive impairment}}, journal = {Psychological medicine}, year = {2013}, doi = {10.1017/s0033291712001870}, pmid = {22954311}, url = {https://doi.org/10.1017/s0033291712001870} } @article{cousins2022-36041863, author = {Cousins, K. A. Q. and Arezoumandan, S. and Shellikeri, S. and Ohm, D. and Shaw, L. M. and Grossman, M. and Wolk, D. and McMillan, C. T. and others}, title = {{CSF Biomarkers of Alzheimer Disease in Patients With Concomitant α-Synuclein Pathology}}, journal = {Neurology}, year = {2022}, doi = {10.1212/wnl.0000000000201202}, pmid = {36041863}, url = {https://doi.org/10.1212/wnl.0000000000201202} } @article{medaglia2017-28779011, author = {Medaglia, J. D. and Huang, W. and Segarra, S. and Olm, C. and Gee, J. and Grossman, M. and Ribeiro, A. and McMillan, C. T. and others}, title = {{Brain network efficiency is influenced by the pathologic source of corticobasal syndrome}}, journal = {Neurology}, year = {2017}, doi = {10.1212/wnl.0000000000004324}, pmid = {28779011}, url = {https://doi.org/10.1212/wnl.0000000000004324} } @article{brown2026-42437499, author = {Brown, C. A. and Robinson, J. L. and Das, SR. and McGrew, E. and Suh, E. and Van Deerlin, V. M. and Irwin, D. J. and Nasrallah, I. M. and others}, title = {{Clinicopathologic Evaluation of Amyloid Clearance in Alzheimer Disease}}, journal = {JAMA}, year = {2026}, doi = {10.1001/jama.2026.13058}, pmid = {42437499}, url = {https://doi.org/10.1001/jama.2026.13058} } @article{staffaroni2020-31914230, author = {Staffaroni, A. M. and Bajorek, L. and Casaletto, K. B. and Cobigo, Y. and Goh, S. M. and Wolf, A. and Heuer, H. W. and Elahi, F. M. and others}, title = {{Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2020}, doi = {10.1016/j.jalz.2019.01.012}, pmid = {31914230}, url = {https://doi.org/10.1016/j.jalz.2019.01.012} } @article{fishman2020-32826748, author = {Fishman, Paul Arthur and White, Lindsay L. Y. and Ingraham, Bailey C. and Park, Sungchul and Larson, Eric B.B. and Crane, Paul K. and Coe, Norma B.}, title = {{Health Care Costs of Alzheimer’s and Related Dementias Within a Medicare Managed Care Provider}}, journal = {Medical Care}, year = {2020}, doi = {10.1097/mlr.0000000000001380}, pmid = {32826748}, url = {https://doi.org/10.1097/mlr.0000000000001380} } @article{mueller2005-16443497, author = {Mueller, Susanne G. and Weiner, Michael Walter and Thal, Leon J. and Petersen, Ronald Carl and Jack, Clifford R. and Jagust, William J. and Trojanowski, John Q. and Toga, Arthur W. and Beckett, Laurel A.}, title = {{The Alzheimer's Disease Neuroimaging Initiative}}, journal = {Neuroimaging Clinics of North America}, year = {2005}, doi = {10.1016/j.nic.2005.09.008}, pmid = {16443497}, url = {https://doi.org/10.1016/j.nic.2005.09.008} } @article{mueller2005-17476317, author = {Mueller, Susanne G. and Weiner, Michael Walter and Thal, Leon J. and Petersen, Ronald Carl and Jack, Clifford R. and Jagust, William J. and Trojanowski, John Q. and Toga, Arthur W. and Beckett, Laurel A.}, title = {{Ways toward an early diagnosis in Alzheimer's disease: The Alzheimer's Disease Neuroimaging Initiative (ADNI)}}, journal = {Alzheimer s \& Dementia}, year = {2005}, doi = {10.1016/j.jalz.2005.06.003}, pmid = {17476317}, url = {https://doi.org/10.1016/j.jalz.2005.06.003} } @article{cousins2026-41447112, author = {Cousins, K. A. Q. and Boyle, R. and Morse, C. and Verma, A. and Brown, C. A. and O'Brien, K. S. and Serper, M. and Dehghani, N. and BioBank, Penn Medicine and McMillan, C. T. and Lee, E. B. and Shaw, L. M. and others}, title = {{Electronic Health Records to Test Multimorbidity Influences to Plasma Biomarker Interpretation for Alzheimer's Disease}}, journal = {Annals of neurology}, year = {2026}, doi = {10.1002/ana.78114}, pmid = {41447112}, url = {https://doi.org/10.1002/ana.78114} } @article{tong2024-39444005, author = {Tong, T. and Zhu, C. and Farrell, J. J. and Khurshid, Z. and {Alzheimer’s Disease Sequencing Project} and {Alzheimer’s Disease Neuroimaging Initiative} and Martin, E. R. and Pericak-Vance, M. A. and others}, title = {{Blood-derived mitochondrial DNA copy number is associated with Alzheimer disease, Alzheimer-related biomarkers and serum metabolites}}, journal = {Alzheimer's research \& therapy}, year = {2024}, doi = {10.1186/s13195-024-01601-w}, pmid = {39444005}, url = {https://doi.org/10.1186/s13195-024-01601-w} } @article{jun2017-28183528, author = {Jun, G. R. and Chung, J. and Mez, J. and Barber, R. and Beecham, G. W. and Bennett, D. A. and Buxbaum, J. D. and Byrd, G. S. and others}, title = {{Transethnic genome-wide scan identifies novel Alzheimer's disease loci}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2017}, doi = {10.1016/j.jalz.2016.12.012}, pmid = {28183528}, url = {https://doi.org/10.1016/j.jalz.2016.12.012} } @article{rubright2010-20808101, author = {Rubright, J. and Sankar, P. and Casarett, D. J. and Gur, R. and Xie, S. X. and Karlawish, J.}, title = {{A memory and organizational aid improves Alzheimer disease research consent capacity: results of a randomized, controlled trial}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2010}, doi = {10.1097/jgp.0b013e3181dd1c3b}, pmid = {20808101}, url = {https://doi.org/10.1097/jgp.0b013e3181dd1c3b} } @article{podcasy2016-28179815, author = {Podcasy, J. L. and Epperson, C. N.}, title = {{Considering sex and gender in Alzheimer disease and other dementias}}, journal = {Dialogues in clinical neuroscience}, year = {2016}, doi = {10.31887/dcns.2016.18.4/cepperson}, pmid = {28179815}, url = {https://doi.org/10.31887/dcns.2016.18.4/cepperson} } @article{study2017-29234814, author = {{US Preventive Services Task Force} and Grossman, D. C. and Curry, S. J. and Owens, D. K. and Barry, M. J. and Davidson, K. W. and Doubeni, C. A. and Epling, J. W. and others}, title = {{Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Women: US Preventive Services Task Force Recommendation Statement}}, journal = {JAMA}, year = {2017}, doi = {10.1001/jama.2017.18261}, pmid = {29234814}, url = {https://doi.org/10.1001/jama.2017.18261} } @article{smith2013-23458973, author = {Smith, D. H. and Johnson, V. E. and Stewart, W.}, title = {{Chronic neuropathologies of single and repetitive TBI: substrates of dementia?}}, journal = {Nature reviews. Neurology}, year = {2013}, doi = {10.1038/nrneurol.2013.29}, pmid = {23458973}, url = {https://doi.org/10.1038/nrneurol.2013.29} } @article{roalf2013-23260866, author = {Roalf, D. R. and Moberg, P. J. and Xie, S. X. and Wolk, D. A. and Moelter, S. T. and Arnold, S. E.}, title = {{Comparative accuracies of two common screening instruments for classification of Alzheimer's disease, mild cognitive impairment, and healthy aging}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2013}, doi = {10.1016/j.jalz.2012.10.001}, pmid = {23260866}, url = {https://doi.org/10.1016/j.jalz.2012.10.001} } @article{chen2011-22094481, author = {Chen, Y. and Wolk, D. A. and Reddin, J. S. and Korczykowski, M. and Martinez, P. M. and Musiek, E. S. and Newberg, A. B. and Julin, P. and others}, title = {{Voxel-level comparison of arterial spin-labeled perfusion MRI and FDG-PET in Alzheimer disease}}, journal = {Neurology}, year = {2011}, doi = {10.1212/wnl.0b013e31823a0ef7}, pmid = {22094481}, url = {https://doi.org/10.1212/wnl.0b013e31823a0ef7} } @article{dickerson2012-22189451, author = {Dickerson, B. C. and Wolk, D. A. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{MRI cortical thickness biomarker predicts AD-like CSF and cognitive decline in normal adults}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e31823efc6c}, pmid = {22189451}, url = {https://doi.org/10.1212/wnl.0b013e31823efc6c} } @article{quiroz2022-35199931, author = {Quiroz, Y. T. and Solis, M. and Aranda, M. P. and Arbaje, A. I. and Arroyo-Miranda, M. and Cabrera, L. Y. and Carrasquillo, M. M. and Corrada, M. M. and others}, title = {{Addressing the disparities in dementia risk, early detection and care in Latino populations: Highlights from the second Latinos \& Alzheimer's Symposium}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2022}, doi = {10.1002/alz.12589}, pmid = {35199931}, url = {https://doi.org/10.1002/alz.12589} } @article{braun2015-26324898, author = {Braun, U. and Schäfer, A. and Walter, H. and Erk, S. and Romanczuk-Seiferth, N. and Haddad, L. and Schweiger, J. I. and Grimm, O. and others}, title = {{Dynamic reconfiguration of frontal brain networks during executive cognition in humans}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2015}, doi = {10.1073/pnas.1422487112}, pmid = {26324898}, url = {https://doi.org/10.1073/pnas.1422487112} } @article{johnson2009-19465477, author = {Johnson, B. S. and Snead, D. and Lee, J. J. and McCaffery, J. M. and Shorter, J. and Gitler, A. D.}, title = {{TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity}}, journal = {The Journal of biological chemistry}, year = {2009}, doi = {10.1074/jbc.m109.010264}, pmid = {19465477}, url = {https://doi.org/10.1074/jbc.m109.010264} } @article{winton2008-18305110, author = {Winton, M. J. and Igaz, L. M. and Wong, M. M. and Kwong, L. K. and Trojanowski, J. Q. and Lee, V. M.}, title = {{Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation}}, journal = {The Journal of biological chemistry}, year = {2008}, doi = {10.1074/jbc.m800342200}, pmid = {18305110}, url = {https://doi.org/10.1074/jbc.m800342200} } @article{mann2019-30826182, author = {Mann, JR. and Gleixner, A. M. and Mauna, J. C. and Gomes, E. and DeChellis-Marks, M. R. and Needham, P. G. and Copley, K. E. and Hurtle, B. and others}, title = {{RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43}}, journal = {Neuron}, year = {2019}, doi = {10.1016/j.neuron.2019.01.048}, pmid = {30826182}, url = {https://doi.org/10.1016/j.neuron.2019.01.048} } @article{clinton2010-20505094, author = {Clinton, L. K. and Blurton-Jones, M. and Myczek, K. and Trojanowski, J. Q. and LaFerla, F. M.}, title = {{Synergistic Interactions between Abeta, tau, and alpha-synuclein: acceleration of neuropathology and cognitive decline}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2010}, doi = {10.1523/jneurosci.0490-10.2010}, pmid = {20505094}, url = {https://doi.org/10.1523/jneurosci.0490-10.2010} } @article{mcgurk2018-30100264, author = {McGurk, L. and Gomes, E. and Guo, L. and Mojsilovic-Petrovic, J. and Tran, V. and Kalb, R. G. and Shorter, J. and Bonini, N. M.}, title = {{Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization}}, journal = {Molecular cell}, year = {2018}, doi = {10.1016/j.molcel.2018.07.002}, pmid = {30100264}, url = {https://doi.org/10.1016/j.molcel.2018.07.002} } @article{kalia2015-25401511, author = {Kalia, L. V. and Lang, A. E. and Hazrati, L. N. and Fujioka, S. and Wszolek, Z. K. and Dickson, D. W. and Ross, O. A. and Van Deerlin, V. M. and others}, title = {{Clinical correlations with Lewy body pathology in LRRK2-related Parkinson disease}}, journal = {JAMA neurology}, year = {2015}, doi = {10.1001/jamaneurol.2014.2704}, pmid = {25401511}, url = {https://doi.org/10.1001/jamaneurol.2014.2704} } @article{misra2009-19027862, author = {Misra, C. and Fan, Y. and Davatzikos, C.}, title = {{Baseline and longitudinal patterns of brain atrophy in MCI patients, and their use in prediction of short-term conversion to AD: results from ADNI}}, journal = {NeuroImage}, year = {2009}, doi = {10.1016/j.neuroimage.2008.10.031}, pmid = {19027862}, url = {https://doi.org/10.1016/j.neuroimage.2008.10.031} } @article{ewers2019-31462511, author = {Ewers, M. and Franzmeier, N. and Suárez-Calvet, M. and Morenas-Rodriguez, E. and Caballero, M. A. A. and Kleinberger, G. and Piccio, L. and Cruchaga, C. and others}, title = {{Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease}}, journal = {Science translational medicine}, year = {2019}, doi = {10.1126/scitranslmed.aav6221}, pmid = {31462511}, url = {https://doi.org/10.1126/scitranslmed.aav6221} } @article{weintraub2015-25737166, author = {Weintraub, D. and Simuni, T. and Caspell-Garcia, C. and Coffey, C. and Lasch, S. and Siderowf, A. and Aarsland, D. and Barone, P. and others}, title = {{Cognitive performance and neuropsychiatric symptoms in early, untreated Parkinson's disease}}, journal = {Movement disorders : official journal of the Movement Disorder Society}, year = {2015}, doi = {10.1002/mds.26170}, pmid = {25737166}, url = {https://doi.org/10.1002/mds.26170} } @article{fullard2016-26923521, author = {Fullard, M. E. and Tran, B. and Xie, S. X. and Toledo, J. B. and Scordia, C. and Linder, C. and Purri, R. and Weintraub, D. and others}, title = {{Olfactory impairment predicts cognitive decline in early Parkinson's disease}}, journal = {Parkinsonism \& related disorders}, year = {2016}, doi = {10.1016/j.parkreldis.2016.02.013}, pmid = {26923521}, url = {https://doi.org/10.1016/j.parkreldis.2016.02.013} } @article{gourmaud2020-31834353, author = {Gourmaud, S. and Shou, H. and Irwin, D. J. and Sansalone, K. and Jacobs, L. M. and Lucas, T. H. and Marsh, E. D. and Davis, K. A. and others}, title = {{Alzheimer-like amyloid and tau alterations associated with cognitive deficit in temporal lobe epilepsy}}, journal = {Brain : a journal of neurology}, year = {2020}, doi = {10.1093/brain/awz381}, pmid = {31834353}, url = {https://doi.org/10.1093/brain/awz381} } @article{ridge2016-27036079, author = {Ridge, P. G. and Hoyt, K. B. and Boehme, K. and Mukherjee, S. and Crane, P. K. and Haines, J. L. and Mayeux, R. and Farrer, L. A. and others}, title = {{Assessment of the genetic variance of late-onset Alzheimer's disease}}, journal = {Neurobiology of aging}, year = {2016}, doi = {10.1016/j.neurobiolaging.2016.02.024}, pmid = {27036079}, url = {https://doi.org/10.1016/j.neurobiolaging.2016.02.024} } @article{sayed2021-34851693, author = {Sayed, F. A. and Kodama, L. and Fan, L. and Carling, G. K. and Udeochu, J. C. and Le, D. and Li, Q. and Zhou, L. and others}, title = {{AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation}}, journal = {Science translational medicine}, year = {2021}, doi = {10.1126/scitranslmed.abe3947}, pmid = {34851693}, url = {https://doi.org/10.1126/scitranslmed.abe3947} } @article{bian2008-18458217, author = {Bian, H. and Van Swieten, J. C. and Leight, S. and Massimo, L. and Wood, E. and Forman, M. and Moore, P. and de Koning, I. and others}, title = {{CSF biomarkers in frontotemporal lobar degeneration with known pathology}}, journal = {Neurology}, year = {2008}, doi = {10.1212/01.wnl.0000311445.21321.fc}, pmid = {18458217}, url = {https://doi.org/10.1212/01.wnl.0000311445.21321.fc} } @article{kim2017-28887373, author = {Kim, B. J. and Irwin, D. J. and Song, D. and Daniel, E. and Leveque, J. D. and Raquib, A. R. and Pan, W. and Ying, G. S. and others}, title = {{Optical coherence tomography identifies outer retina thinning in frontotemporal degeneration}}, journal = {Neurology}, year = {2017}, doi = {10.1212/wnl.0000000000004500}, pmid = {28887373}, url = {https://doi.org/10.1212/wnl.0000000000004500} } @article{coughlin2025-41248454, author = {Coughlin, D. G. and Jain, L. and Khrestian, M. and Bozoki, A. C. and Galvin, J. E. and Irwin, D. J. and Lippa, C. F. and Litvan, I. and others}, title = {{CSF α-Synuclein Seed Amplification Assays and Alzheimer Disease Biomarkers in Dementia With Lewy Bodies: Presentation and Progression}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000214346}, pmid = {41248454}, url = {https://doi.org/10.1212/wnl.0000000000214346} } @article{urwin2010-20490813, author = {Urwin, H. and Josephs, K. A. and Rohrer, J. D. and Mackenzie, I. R. and Neumann, M. and Authier, A. and Seelaar, H. and Van Swieten, J. C. and others}, title = {{FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration}}, journal = {Acta neuropathologica}, year = {2010}, doi = {10.1007/s00401-010-0698-6}, pmid = {20490813}, url = {https://doi.org/10.1007/s00401-010-0698-6} } @article{drake2019-31108509, author = {Drake, Coleman and Zhang, Yuehan and Chaiyachati, Krisda H. and Polsky, Daniel E.}, title = {{The Limitations of Poor Broadband Internet Access for Telemedicine Use in Rural America: An Observational Study}}, journal = {Annals of Internal Medicine}, year = {2019}, doi = {10.7326/m19-0283}, pmid = {31108509}, url = {https://doi.org/10.7326/m19-0283} } @article{elo2026-e026a1f9, author = {Elo, Irma T. and Mani, Sneha Sarah and Delaporte, Magdalena and Bravo, David and Behrman, Jere}, title = {{The Chilean harmonized cognitive assessment protocol (Chile-Cog): study design}}, journal = {BMC Public Health}, year = {2026}, doi = {10.1186/s12889-026-28784-1}, url = {https://doi.org/10.1186/s12889-026-28784-1} } @article{njamnshi2025-41395729, author = {Njamnshi, Wepnyu Yembe and Chiotis, Konstantinos and Tsoy, Elena and Blazhenets, Ganna and Maiti, Piyush and Zhang, Jiaxiuxiu and Allen, Isabel Elaine and Rocha, Salma and others}, title = {{Tablet‐based Cognitive Assessment Tool (TabCAT) in a multisite study of early‐onset Alzheimer's disease}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.71012}, pmid = {41395729}, url = {https://doi.org/10.1002/alz.71012} } @article{mekonnen2025-40211155, author = {Mekonnen, Teferi and Skirbekk, Vegard and Haberg, Asta Kristine and Engdahl, Bo and Zotcheva, Ekaterina and Jugessur, Astanand and Bowen, Catherine E. and Selbæk, Geir and others}, title = {{Mediators of educational differences in dementia risk later in life: evidence from the HUNT study}}, journal = {BMC Public Health}, year = {2025}, doi = {10.1186/s12889-025-22592-9}, pmid = {40211155}, url = {https://doi.org/10.1186/s12889-025-22592-9} } @article{moin2025-40331620, author = {Moin, Emily E. and Bayes, Brian A. and Madden, Vanessa L. and Halpern, Scott D. and Courtright, Katherine R.}, title = {{Disease and Race‐Based Differences in Inpatient Palliative Care Consultation in Cancer and Noncancer Serious Illnesses}}, journal = {Journal of the American Geriatrics Society}, year = {2025}, doi = {10.1111/jgs.19509}, pmid = {40331620}, url = {https://doi.org/10.1111/jgs.19509} } @article{pruzin2025-41159258, author = {Pruzin, Jeremy J. and Yau, Wai‐Ying Wendy and Bress, Adam Phillip and Baradaran, Hediyeh and Chhatwal, Jasmeer P. and Tariot, Pierre N. and Cushman, William C. and Gupta, Aditi and others}, title = {{Effect of Intensive Systolic Blood Pressure Control on Markers of Cerebral Small Vessel Disease by Age}}, journal = {Hypertension}, year = {2025}, doi = {10.1161/hypertensionaha.125.25202}, pmid = {41159258}, url = {https://doi.org/10.1161/hypertensionaha.125.25202} } @article{li2023-37260021, author = {Li, D. and Farrell, J. J. and Mez, J. and Martin, E. R. and Bush, W. S. and Ruiz, A. and Boada, M. and de Rojas, I. and Mayeux, R. and Haines, J. L. and Vance, M. A. P. and Wang, L. S. and others}, title = {{Novel loci for Alzheimer's disease identified by a genome-wide association study in Ashkenazi Jews}}, journal = {Alzheimer's \& Dementia}, year = {2023}, doi = {10.1002/alz.13117}, pmid = {37260021}, url = {https://doi.org/10.1002/alz.13117} } @article{hu2010-20713948, author = {Hu, W. T. and McMillan, C. and Libon, D. and Leight, S. and Forman, M. and Lee, V. M. and Trojanowski, J. Q. and Grossman, M.}, title = {{Multimodal predictors for Alzheimer disease in nonfluent primary progressive aphasia}}, journal = {Neurology}, year = {2010}, doi = {10.1212/wnl.0b013e3181ed9c52}, pmid = {20713948}, url = {https://doi.org/10.1212/wnl.0b013e3181ed9c52} } @article{luk2009-19892735, author = {Luk, K. C. and Song, C. and O'Brien, P. and Stieber, A. and Branch, JR. and Brunden, K. R. and Trojanowski, J. Q. and Lee, V. M.}, title = {{Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2009}, doi = {10.1073/pnas.0908005106}, pmid = {19892735}, url = {https://doi.org/10.1073/pnas.0908005106} } @article{iba2013-23325240, author = {Iba, M. and Guo, J. L. and McBride, J. D. and Zhang, B. and Trojanowski, J. Q. and Lee, V. M.}, title = {{Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2013}, doi = {10.1523/jneurosci.2642-12.2013}, pmid = {23325240}, url = {https://doi.org/10.1523/jneurosci.2642-12.2013} } @article{king2012-22445064, author = {King, O. D. and Gitler, A. D. and Shorter, J.}, title = {{The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease}}, journal = {Brain research}, year = {2012}, doi = {10.1016/j.brainres.2012.01.016}, pmid = {22445064}, url = {https://doi.org/10.1016/j.brainres.2012.01.016} } @article{sun2011-21541367, author = {Sun, Z. and Diaz, Z. and Fang, X. and Hart, M. P. and Chesi, A. and Shorter, J. and Gitler, A. D.}, title = {{Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS}}, journal = {PLoS biology}, year = {2011}, doi = {10.1371/journal.pbio.1000614}, pmid = {21541367}, url = {https://doi.org/10.1371/journal.pbio.1000614} } @article{igaz2011-21206091, author = {Igaz, L. M. and Kwong, L. K. and Lee, E. B. and Chen-Plotkin, A. and Swanson, E. and Unger, T. and Malunda, J. and Xu, Y. and others}, title = {{Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice}}, journal = {The Journal of clinical investigation}, year = {2011}, doi = {10.1172/jci44867}, pmid = {21206091}, url = {https://doi.org/10.1172/jci44867} } @article{fan2008-18053747, author = {Fan, Y. and Batmanghelich, N. and Clark, C. M. and Davatzikos, C. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{Spatial patterns of brain atrophy in MCI patients, identified via high-dimensional pattern classification, predict subsequent cognitive decline}}, journal = {NeuroImage}, year = {2008}, doi = {10.1016/j.neuroimage.2007.10.031}, pmid = {18053747}, url = {https://doi.org/10.1016/j.neuroimage.2007.10.031} } @article{trojanowski2010-20451871, author = {Trojanowski, J. Q. and Vandeerstichele, H. and Korecka, M. and Clark, C. M. and Aisen, P. S. and Petersen, R. C. and Blennow, K. and Soares, H. and others}, title = {{Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2010}, doi = {10.1016/j.jalz.2010.03.008}, pmid = {20451871}, url = {https://doi.org/10.1016/j.jalz.2010.03.008} } @article{pereira2014-24808018, author = {Pereira, J. B. and Svenningsson, P. and Weintraub, D. and Brønnick, K. and Lebedev, A. and Westman, E. and Aarsland, D.}, title = {{Initial cognitive decline is associated with cortical thinning in early Parkinson disease}}, journal = {Neurology}, year = {2014}, doi = {10.1212/wnl.0000000000000483}, pmid = {24808018}, url = {https://doi.org/10.1212/wnl.0000000000000483} } @article{wolk2017-27836336, author = {Wolk, D. A. and Das, SR. and Mueller, S. G. and Weiner, M. W. and Yushkevich, P. A. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{Medial temporal lobe subregional morphometry using high resolution MRI in Alzheimer's disease}}, journal = {Neurobiology of aging}, year = {2017}, doi = {10.1016/j.neurobiolaging.2016.09.011}, pmid = {27836336}, url = {https://doi.org/10.1016/j.neurobiolaging.2016.09.011} } @article{toledo2015-26085606, author = {Toledo, J. B. and Bjerke, M. and Chen, K. and Rozycki, M. and Jack, C. R. and Weiner, M. W. and Arnold, S. E. and Reiman, E. M. and others}, title = {{Memory, executive, and multidomain subtle cognitive impairment: clinical and biomarker findings}}, journal = {Neurology}, year = {2015}, doi = {10.1212/wnl.0000000000001738}, pmid = {26085606}, url = {https://doi.org/10.1212/wnl.0000000000001738} } @article{irwin2015-25549971, author = {Irwin, D. J. and Cairns, N. J. and Grossman, M. and McMillan, C. T. and Lee, E. B. and Van Deerlin, V. M. and Lee, V. M. and Trojanowski, J. Q.}, title = {{Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine}}, journal = {Acta neuropathologica}, year = {2015}, doi = {10.1007/s00401-014-1380-1}, pmid = {25549971}, url = {https://doi.org/10.1007/s00401-014-1380-1} } @article{petersen2025-41442191, author = {Petersen, Kellen K. and Milà‐Alomà, Marta and Tosun, Duygu and Li, Yan and Saef, Benjamin A. and Shaw, Leslie M. and Dage, Jeffrey L. and Zetterberg, Henrik and others}, title = {{Predicting onset of Alzheimer disease symptoms with a plasma \%p‐tau217 clock}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz70856_099674}, pmid = {41442191}, url = {https://doi.org/10.1002/alz70856_099674} } @article{baumeister2025-40691867, author = {Baumeister, Hannah and Gellersen, Helena Marie and Polk, Sarah E. and Lattmann, René and Wuestefeld, Anika and Wisse, Laura E.M. and Glenn, Trevor W. and Yakupov, Renat and others}, title = {{Disease stage–specific atrophy markers in Alzheimer's disease}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70482}, pmid = {40691867}, url = {https://doi.org/10.1002/alz.70482} } @article{maust2025-40145303, author = {Maust, Donovan T. and Davis, Rachel E. and Muench, Ulrike and Marcus, Steven C. and Spetz, Joanne}, title = {{Clinician type and care setting for treatment of Medicare beneficiaries with dementia}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70102}, pmid = {40145303}, url = {https://doi.org/10.1002/alz.70102} } @article{liu2025-40277074, author = {Liu, Xulin and de Boer, Sterre C.M. and Cortez, Kasey and Poos, Jackie M. and Illán‐Gala, Ignacio and Heuer, Hilary W. and Forsberg, Leah K. and Casaletto, Kaitlin Blackstone and others}, title = {{Sex differences in clinical phenotypes of behavioral variant frontotemporal dementia}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.14608}, pmid = {40277074}, url = {https://doi.org/10.1002/alz.14608} } @article{hyman1997-9329452, author = {Hyman, Bradley T. and Trojanowski, John Q.}, title = {{Editorial on Consensus Recommendations for the Postmortem Diagnosis of Alzheimer Disease from the National Institute on Aging and the Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer Disease}}, journal = {Journal of Neuropathology \& Experimental Neurology}, year = {1997}, doi = {10.1097/00005072-199710000-00002}, pmid = {9329452}, url = {https://doi.org/10.1097/00005072-199710000-00002} } @article{duggan2024-39143319, author = {Duggan, M. R. and Peng, Z. and Sipilä, P. N. and Lindbohm, J. V. and Chen, J. and Lu, Y. and Davatzikos, C. and Erus, G. and others}, title = {{Proteomics identifies potential immunological drivers of postinfection brain atrophy and cognitive decline}}, journal = {Nature aging}, year = {2024}, doi = {10.1038/s43587-024-00682-4}, pmid = {39143319}, url = {https://doi.org/10.1038/s43587-024-00682-4} } @article{christakis1996-8657216, author = {Christakis, N. A. and Escarce, J. J.}, title = {{Survival of Medicare patients after enrollment in hospice programs}}, journal = {The New England journal of medicine}, year = {1996}, doi = {10.1056/nejm199607183350306}, pmid = {8657216}, url = {https://doi.org/10.1056/nejm199607183350306} } @article{cook2020-32878979, author = {Cook, C. N. and Wu, Y. and Odeh, H. M. and Gendron, T. F. and Jansen-West, K. and Del Rosso, G. and Yue, M. and Jiang, P. and others}, title = {{C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy}}, journal = {Science translational medicine}, year = {2020}, doi = {10.1126/scitranslmed.abb3774}, pmid = {32878979}, url = {https://doi.org/10.1126/scitranslmed.abb3774} } @article{martinezmartin2015-25892660, author = {Martinez-Martin, P. and Rodriguez-Blazquez, C. and Forjaz, M. J. and Frades-Payo, B. and Agüera-Ortiz, L. and Weintraub, D. and Riesco, A. and Kurtis, M. M. and others}, title = {{Neuropsychiatric symptoms and caregiver's burden in Parkinson's disease}}, journal = {Parkinsonism \& related disorders}, year = {2015}, doi = {10.1016/j.parkreldis.2015.03.024}, pmid = {25892660}, url = {https://doi.org/10.1016/j.parkreldis.2015.03.024} } @article{irwin2018-29228211, author = {Irwin, D. J. and McMillan, C. T. and Xie, S. X. and Rascovsky, K. and Van Deerlin, V. M. and Coslett, H. B. and Hamilton, R. and Aguirre, G. K. and others}, title = {{Asymmetry of post-mortem neuropathology in behavioural-variant frontotemporal dementia}}, journal = {Brain : a journal of neurology}, year = {2018}, doi = {10.1093/brain/awx319}, pmid = {29228211}, url = {https://doi.org/10.1093/brain/awx319} } @article{nevler2017-28724588, author = {Nevler, N. and Ash, S. and Jester, C. and Irwin, D. J. and Liberman, M. and Grossman, M.}, title = {{Automatic measurement of prosody in behavioral variant FTD}}, journal = {Neurology}, year = {2017}, doi = {10.1212/wnl.0000000000004236}, pmid = {28724588}, url = {https://doi.org/10.1212/wnl.0000000000004236} } @article{dsouza1999-10318930, author = {D'Souza, I. and Poorkaj, P. and Hong, M. and Nochlin, D. and Lee, V. M. and Bird, T. D. and Schellenberg, G. D.}, title = {{Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {1999}, doi = {10.1073/pnas.96.10.5598}, pmid = {10318930}, url = {https://doi.org/10.1073/pnas.96.10.5598} } @article{uryu2008-18520774, author = {Uryu, K. and Nakashima-Yasuda, H. and Forman, M. S. and Kwong, L. K. and Clark, C. M. and Grossman, M. and Miller, B. L. and Kretzschmar, H. A. and others}, title = {{Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies}}, journal = {Journal of neuropathology and experimental neurology}, year = {2008}, doi = {10.1097/nen.0b013e31817713b5}, pmid = {18520774}, url = {https://doi.org/10.1097/nen.0b013e31817713b5} } @article{igaz2009-19164285, author = {Igaz, L. M. and Kwong, L. K. and Chen-Plotkin, A. and Winton, M. J. and Unger, T. L. and Xu, Y. and Neumann, M. and Trojanowski, J. Q. and others}, title = {{Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies}}, journal = {The Journal of biological chemistry}, year = {2009}, doi = {10.1074/jbc.m809462200}, pmid = {19164285}, url = {https://doi.org/10.1074/jbc.m809462200} } @article{deleon2004-15324364, author = {de Leon, M. J. and DeSanti, S. and Zinkowski, R. and Mehta, P. D. and Pratico, D. and Segal, S. and Clark, C. and Kerkman, D. and others}, title = {{MRI and CSF studies in the early diagnosis of Alzheimer's disease}}, journal = {Journal of internal medicine}, year = {2004}, doi = {10.1111/j.1365-2796.2004.01381.x}, pmid = {15324364}, url = {https://doi.org/10.1111/j.1365-2796.2004.01381.x} } @article{chen2011-21276856, author = {Chen, K. and Ayutyanont, N. and Langbaum, J. B. and Fleisher, A. S. and Reschke, C. and Lee, W. and Liu, X. and Bandy, D. and others}, title = {{Characterizing Alzheimer's disease using a hypometabolic convergence index}}, journal = {NeuroImage}, year = {2011}, doi = {10.1016/j.neuroimage.2011.01.049}, pmid = {21276856}, url = {https://doi.org/10.1016/j.neuroimage.2011.01.049} } @article{dickerson2011-20562467, author = {Dickerson, B. C. and Wolk, D. A. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{Dysexecutive versus amnesic phenotypes of very mild Alzheimer's disease are associated with distinct clinical, genetic and cortical thinning characteristics}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2011}, doi = {10.1136/jnnp.2009.199505}, pmid = {20562467}, url = {https://doi.org/10.1136/jnnp.2009.199505} } @article{shi2018-29604263, author = {Shi, M. and Tang, L. and Toledo, J. B. and Ginghina, C. and Wang, H. and Aro, P. and Jensen, P. H. and Weintraub, D. and others}, title = {{Cerebrospinal fluid α-synuclein contributes to the differential diagnosis of Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2018}, doi = {10.1016/j.jalz.2018.02.015}, pmid = {29604263}, url = {https://doi.org/10.1016/j.jalz.2018.02.015} } @article{yarchoan2012-23204143, author = {Yarchoan, M. and Xie, S. X. and Kling, M. A. and Toledo, J. B. and Wolk, D. A. and Lee, E. B. and Van Deerlin, V. and Lee, V. M. and others}, title = {{Cerebrovascular atherosclerosis correlates with Alzheimer pathology in neurodegenerative dementias}}, journal = {Brain : a journal of neurology}, year = {2012}, doi = {10.1093/brain/aws271}, pmid = {23204143}, url = {https://doi.org/10.1093/brain/aws271} } @article{chenplotkin2012-22895706, author = {Chen-Plotkin, A. S. and Unger, T. L. and Gallagher, M. D. and Bill, E. and Kwong, L. K. and Volpicelli-Daley, L. and Busch, J. I. and Akle, S. and others}, title = {{TMEM106B, the risk gene for frontotemporal dementia, is regulated by the microRNA-132/212 cluster and affects progranulin pathways}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2012}, doi = {10.1523/jneurosci.0521-12.2012}, pmid = {22895706}, url = {https://doi.org/10.1523/jneurosci.0521-12.2012} } @article{werner2025-40377938, author = {Werner, Rachel M. and Kim, Seiyoun and Konetzka, Rita Tamara}, title = {{Trends in Home Health Care Among Traditional Medicare Beneficiaries With or Without Dementia}}, journal = {JAMA Network Open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.10933}, pmid = {40377938}, url = {https://doi.org/10.1001/jamanetworkopen.2025.10933} } @article{mieling2025-40285975, author = {Mieling, Marthe and Yousuf, Mushfa and Bunzeck, Nico and {Alzheimer’s Disease Neuroimaging Initiative} and Weiner, Michael and Aisen, Paul and Petersen, Ronald and Jack, Clifford R. and others}, title = {{Predicting the progression of MCI and Alzheimer’s disease on structural brain integrity and other features with machine learning}}, journal = {GeroScience}, year = {2025}, doi = {10.1007/s11357-025-01626-5}, pmid = {40285975}, url = {https://doi.org/10.1007/s11357-025-01626-5} } @article{blujdea2026-41814022, author = {Blujdea, Elena Raluca and van Bokhoven, Pieter and Adami, Pamela V. Martino and Marshe, Victoria S. and Vromen, Ellen and Hok-A-Hin, Yanaika Sylvana and Boiten, Walter A. and Irwin, David John and others}, title = {{Microglia protein profiles in CSF across Alzheimer’s disease clinical stages}}, journal = {Nature Aging}, year = {2026}, doi = {10.1038/s43587-026-01088-0}, pmid = {41814022}, url = {https://doi.org/10.1038/s43587-026-01088-0} } @article{sun2026-42066773, author = {Sun, X. and Mews, M. and Wheeler, N. R. and Benchek, P. and Gu, T. and Gomez, L. and Ray, N. and Reitz, C. and Naj, A. C. and Below, J. E. and Tosto, G. and Cornejo-Olivas, M. and others}, title = {{Multi-ancestry transcriptome-wide association study reveals shared and population-specific genetic effects in Alzheimer disease}}, journal = {American Journal of Human Genetics}, year = {2026}, doi = {10.1016/j.ajhg.2026.04.007}, pmid = {42066773}, url = {https://doi.org/10.1016/j.ajhg.2026.04.007} } @article{sanchezjuan2014-24353340, author = {Sánchez-Juan, P. and Ghosh, P. M. and Hagen, J. and Gesierich, B. and Henry, M. and Grinberg, L. T. and O'Neil, J. P. and Janabi, M. and others}, title = {{Practical utility of amyloid and FDG-PET in an academic dementia center}}, journal = {Neurology}, year = {2014}, doi = {10.1212/wnl.0000000000000032}, pmid = {24353340}, url = {https://doi.org/10.1212/wnl.0000000000000032} } @article{mozersky2018-29059270, author = {Mozersky, J. and Sankar, P. and Harkins, K. and Hachey, S. and Karlawish, J.}, title = {{Comprehension of an Elevated Amyloid Positron Emission Tomography Biomarker Result by Cognitively Normal Older Adults}}, journal = {JAMA neurology}, year = {2018}, doi = {10.1001/jamaneurol.2017.2954}, pmid = {29059270}, url = {https://doi.org/10.1001/jamaneurol.2017.2954} } @article{bonomi2024-38038976, author = {Bonomi, S. and Lu, R. and Schindler, S. E. and Bui, Q. and Lah, J. J. and Wolk, D. and Gleason, C. E. and Sperling, R. and others}, title = {{Relationships of Cognitive Measures with Cerebrospinal Fluid but Not Imaging Biomarkers of Alzheimer Disease Vary between Black and White Individuals}}, journal = {Annals of neurology}, year = {2024}, doi = {10.1002/ana.26838}, pmid = {38038976}, url = {https://doi.org/10.1002/ana.26838} } @article{duda2002-12210791, author = {Duda, J. E. and Giasson, B. I. and Mabon, M. E. and Lee, V. M. and Trojanowski, J. Q.}, title = {{Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases}}, journal = {Annals of neurology}, year = {2002}, doi = {10.1002/ana.10279}, pmid = {12210791}, url = {https://doi.org/10.1002/ana.10279} } @article{bassil2020-31759806, author = {Bassil, F. and Brown, H. J. and Pattabhiraman, S. and Iwasyk, J. E. and Maghames, C. M. and Meymand, E. S. and Cox, T. O. and Riddle, D. M. and others}, title = {{Amyloid-Beta (Aβ) Plaques Promote Seeding and Spreading of Alpha-Synuclein and Tau in a Mouse Model of Lewy Body Disorders with Aβ Pathology}}, journal = {Neuron}, year = {2020}, doi = {10.1016/j.neuron.2019.10.010}, pmid = {31759806}, url = {https://doi.org/10.1016/j.neuron.2019.10.010} } @article{arvanitakis2006-17159101, author = {Arvanitakis, Z. and Schneider, J. A. and Wilson, R. S. and Li, Y. and Arnold, S. E. and Wang, Z. and Bennett, D. A.}, title = {{Diabetes is related to cerebral infarction but not to AD pathology in older persons}}, journal = {Neurology}, year = {2006}, doi = {10.1212/01.wnl.0000247053.45483.4e}, pmid = {17159101}, url = {https://doi.org/10.1212/01.wnl.0000247053.45483.4e} } @article{mitchell2012-22213494, author = {Mitchell, S. L. and Black, B. S. and Ersek, M. and Hanson, L. C. and Miller, S. C. and Sachs, G. A. and Teno, J. M. and Morrison, R. S.}, title = {{Advanced dementia: state of the art and priorities for the next decade}}, journal = {Annals of internal medicine}, year = {2012}, doi = {10.7326/0003-4819-156-1-201201030-00008}, pmid = {22213494}, url = {https://doi.org/10.7326/0003-4819-156-1-201201030-00008} } @article{cairns2004-15505152, author = {Cairns, N. J. and Grossman, M. and Arnold, S. E. and Burn, D. J. and Jaros, E. and Perry, R. H. and Duyckaerts, C. and Stankoff, B. and others}, title = {{Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease}}, journal = {Neurology}, year = {2004}, doi = {10.1212/01.wnl.0000139809.16817.dd}, pmid = {15505152}, url = {https://doi.org/10.1212/01.wnl.0000139809.16817.dd} } @article{varatharajah2019-30783207, author = {Varatharajah, Y. and Ramanan, V. K. and Iyer, R. and Vemuri, P. and {Alzheimer’s Disease Neuroimaging Initiative}}, title = {{Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics}}, journal = {Scientific reports}, year = {2019}, doi = {10.1038/s41598-019-38793-3}, pmid = {30783207}, url = {https://doi.org/10.1038/s41598-019-38793-3} } @article{weintraub2011-21626547, author = {Weintraub, D. and Burn, D. J.}, title = {{Parkinson's disease: the quintessential neuropsychiatric disorder}}, journal = {Movement disorders : official journal of the Movement Disorder Society}, year = {2011}, doi = {10.1002/mds.23664}, pmid = {21626547}, url = {https://doi.org/10.1002/mds.23664} } @article{ishihara1999-10595524, author = {Ishihara, T. and Hong, M. and Zhang, B. and Nakagawa, Y. and Lee, M. K. and Trojanowski, J. Q. and Lee, V. M.}, title = {{Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform}}, journal = {Neuron}, year = {1999}, doi = {10.1016/s0896-6273(00)81127-7}, pmid = {10595524}, url = {https://doi.org/10.1016/s0896-6273(00)81127-7} } @article{harrison2017-28389532, author = {Harrison, A. F. and Shorter, J.}, title = {{RNA-binding proteins with prion-like domains in health and disease}}, journal = {The Biochemical journal}, year = {2017}, doi = {10.1042/bcj20160499}, pmid = {28389532}, url = {https://doi.org/10.1042/bcj20160499} } @article{da2014-24371799, author = {Da, X. and Toledo, J. B. and Zee, J. and Wolk, D. A. and Xie, S. X. and Ou, Y. and Shacklett, A. and Parmpi, P. and others}, title = {{Integration and relative value of biomarkers for prediction of MCI to AD progression: spatial patterns of brain atrophy, cognitive scores, APOE genotype and CSF biomarkers}}, journal = {NeuroImage. Clinical}, year = {2014}, doi = {10.1016/j.nicl.2013.11.010}, pmid = {24371799}, url = {https://doi.org/10.1016/j.nicl.2013.11.010} } @article{prokop2019-31350575, author = {Prokop, S. and Miller, K. R. and Labra, SR. and Pitkin, R. M. and Hoxha, K. and Narasimhan, S. and Changolkar, L. and Rosenbloom, A. and others}, title = {{Impact of TREM2 risk variants on brain region-specific immune activation and plaque microenvironment in Alzheimer's disease patient brain samples}}, journal = {Acta neuropathologica}, year = {2019}, doi = {10.1007/s00401-019-02048-2}, pmid = {31350575}, url = {https://doi.org/10.1007/s00401-019-02048-2} } @article{igaz2008-18535185, author = {Igaz, L. M. and Kwong, L. K. and Xu, Y. and Truax, A. C. and Uryu, K. and Neumann, M. and Clark, C. M. and Elman, L. B. and others}, title = {{Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis}}, journal = {The American journal of pathology}, year = {2008}, doi = {10.2353/ajpath.2008.080003}, pmid = {18535185}, url = {https://doi.org/10.2353/ajpath.2008.080003} } @article{stirland2025-40755143, author = {Stirland, Lucy and Choate, Radmila and Zanwar, Preeti and Zhang, Panpan and Watermeyer, Tamlyn and Valletta, Martina and Torso, Mario and Tamburin, Stefano and others}, title = {{Multimorbidity in dementia: Current perspectives and future challenges}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70546}, pmid = {40755143}, url = {https://doi.org/10.1002/alz.70546} } @article{obrien2026-42254757, author = {O'Brien, K. and Coykendall, C. and Harkins, K. and Wang, X. and Perelman, A. and Zhang, M. and Karlawish, J.}, title = {{Study of the utility and impact of a plasma p-tau181 Alzheimer's biomarker (SUITABLE)}}, journal = {Alzheimer's \& Dementia: Translational Research \& Clinical Interventions}, year = {2026}, doi = {10.1002/trc2.70207}, pmid = {42254757}, url = {https://doi.org/10.1002/trc2.70207} } @article{wolk2011-21747004, author = {Wolk, D. A. and Grachev, I. D. and Buckley, C. and Kazi, H. and Grady, M. S. and Trojanowski, J. Q. and Hamilton, R. H. and Sherwin, P. and others}, title = {{Association between in vivo fluorine 18-labeled flutemetamol amyloid positron emission tomography imaging and in vivo cerebral cortical histopathology}}, journal = {Archives of neurology}, year = {2011}, doi = {10.1001/archneurol.2011.153}, pmid = {21747004}, url = {https://doi.org/10.1001/archneurol.2011.153} } @article{duong2021-33841127, author = {Duong, M. T. and Nasrallah, I. M. and Wolk, D. A. and Chang, C. C. Y. and Chang, T. Y.}, title = {{Cholesterol, Atherosclerosis, and APOE in Vascular Contributions to Cognitive Impairment and Dementia (VCID): Potential Mechanisms and Therapy}}, journal = {Frontiers in aging neuroscience}, year = {2021}, doi = {10.3389/fnagi.2021.647990}, pmid = {33841127}, url = {https://doi.org/10.3389/fnagi.2021.647990} } @article{grill2013-23255824, author = {Grill, J. D. and Raman, R. and Ernstrom, K. and Aisen, P. and Karlawish, J.}, title = {{Effect of study partner on the conduct of Alzheimer disease clinical trials}}, journal = {Neurology}, year = {2013}, doi = {10.1212/wnl.0b013e31827debfe}, pmid = {23255824}, url = {https://doi.org/10.1212/wnl.0b013e31827debfe} } @article{kim2011-21300949, author = {Kim, S. Y. and Karlawish, J. H. and Kim, H. M. and Wall, I. F. and Bozoki, A. C. and Appelbaum, P. S.}, title = {{Preservation of the capacity to appoint a proxy decision maker: implications for dementia research}}, journal = {Archives of general psychiatry}, year = {2011}, doi = {10.1001/archgenpsychiatry.2010.191}, pmid = {21300949}, url = {https://doi.org/10.1001/archgenpsychiatry.2010.191} } @article{karlawish2008-18556397, author = {Karlawish, J. and Kim, S. Y. and Knopman, D. and van Dyck, C. H. and James, B. D. and Marson, D.}, title = {{Interpreting the clinical significance of capacity scores for informed consent in Alzheimer disease clinical trials}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2008}, doi = {10.1097/jgp.0b013e318172b406}, pmid = {18556397}, url = {https://doi.org/10.1097/jgp.0b013e318172b406} } @article{cummings2007-17938373, author = {Cummings, J. L. and Doody, R. and Clark, C.}, title = {{Disease-modifying therapies for Alzheimer disease: challenges to early intervention}}, journal = {Neurology}, year = {2007}, doi = {10.1212/01.wnl.0000295996.54210.69}, pmid = {17938373}, url = {https://doi.org/10.1212/01.wnl.0000295996.54210.69} } @article{toledo2013-24252435, author = {Toledo, J. B. and Cairns, N. J. and Da, X. and Chen, K. and Carter, D. and Fleisher, A. and Householder, E. and Ayutyanont, N. and others}, title = {{Clinical and multimodal biomarker correlates of ADNI neuropathological findings}}, journal = {Acta neuropathologica communications}, year = {2013}, doi = {10.1186/2051-5960-1-65}, pmid = {24252435}, url = {https://doi.org/10.1186/2051-5960-1-65} } @article{kenney2018-29155947, author = {Kenney, K. and Iacono, D. and Edlow, B. L. and Katz, D. I. and Diaz-Arrastia, R. and Dams-O'Connor, K. and Daneshvar, D. H. and Stevens, A. and others}, title = {{Dementia After Moderate-Severe Traumatic Brain Injury: Coexistence of Multiple Proteinopathies}}, journal = {Journal of neuropathology and experimental neurology}, year = {2018}, doi = {10.1093/jnen/nlx101}, pmid = {29155947}, url = {https://doi.org/10.1093/jnen/nlx101} } @article{weintraub2011-21747029, author = {Weintraub, D. and Chen, P. and Ignacio, R. V. and Mamikonyan, E. and Kales, H. C.}, title = {{Patterns and trends in antipsychotic prescribing for Parkinson disease psychosis}}, journal = {Archives of neurology}, year = {2011}, doi = {10.1001/archneurol.2011.139}, pmid = {21747029}, url = {https://doi.org/10.1001/archneurol.2011.139} } @article{gonzalezscarano2005-15630430, author = {González-Scarano, F. and Martín-García, J.}, title = {{The neuropathogenesis of AIDS}}, journal = {Nature reviews. Immunology}, year = {2005}, doi = {10.1038/nri1527}, pmid = {15630430}, url = {https://doi.org/10.1038/nri1527} } @article{ash2009-22180700, author = {Ash, S. and Moore, P. and Vesely, L. and Gunawardena, D. and McMillan, C. and Anderson, C. and Avants, B. and Grossman, M.}, title = {{Non-Fluent Speech in Frontotemporal Lobar Degeneration}}, journal = {Journal of neurolinguistics}, year = {2009}, doi = {10.1016/j.jneuroling.2008.12.001}, pmid = {22180700}, url = {https://doi.org/10.1016/j.jneuroling.2008.12.001} } @article{gunawardena2010-20713947, author = {Gunawardena, D. and Ash, S. and McMillan, C. and Avants, B. and Gee, J. and Grossman, M.}, title = {{Why are patients with progressive nonfluent aphasia nonfluent?}}, journal = {Neurology}, year = {2010}, doi = {10.1212/wnl.0b013e3181ed9c7d}, pmid = {20713947}, url = {https://doi.org/10.1212/wnl.0b013e3181ed9c7d} } @article{giannini2021-33622418, author = {Giannini, L. A. A. and Peterson, C. and Ohm, D. and Xie, S. X. and McMillan, C. T. and Raskovsky, K. and Massimo, L. and Suh, E. and others}, title = {{Frontotemporal lobar degeneration proteinopathies have disparate microscopic patterns of white and grey matter pathology}}, journal = {Acta neuropathologica communications}, year = {2021}, doi = {10.1186/s40478-021-01129-2}, pmid = {33622418}, url = {https://doi.org/10.1186/s40478-021-01129-2} } @article{hay2015-26574669, author = {Hay, JR. and Johnson, V. E. and Young, A. M. and Smith, D. H. and Stewart, W.}, title = {{Blood-Brain Barrier Disruption Is an Early Event That May Persist for Many Years After Traumatic Brain Injury in Humans}}, journal = {Journal of neuropathology and experimental neurology}, year = {2015}, doi = {10.1097/nen.0000000000000261}, pmid = {26574669}, url = {https://doi.org/10.1097/nen.0000000000000261} } @article{chenplotkin2010-20234357, author = {Chen-Plotkin, A. S. and Lee, V. M. and Trojanowski, J. Q.}, title = {{TAR DNA-binding protein 43 in neurodegenerative disease}}, journal = {Nature reviews. Neurology}, year = {2010}, doi = {10.1038/nrneurol.2010.18}, pmid = {20234357}, url = {https://doi.org/10.1038/nrneurol.2010.18} } @article{lee2006-17015225, author = {Lee, V. M. and Trojanowski, J. Q.}, title = {{Mechanisms of Parkinson's disease linked to pathological alpha-synuclein: new targets for drug discovery}}, journal = {Neuron}, year = {2006}, doi = {10.1016/j.neuron.2006.09.026}, pmid = {17015225}, url = {https://doi.org/10.1016/j.neuron.2006.09.026} } @article{portz2021-33446423, author = {Portz, B. and Lee, B. L. and Shorter, J.}, title = {{FUS and TDP-43 Phases in Health and Disease}}, journal = {Trends in biochemical sciences}, year = {2021}, doi = {10.1016/j.tibs.2020.12.005}, pmid = {33446423}, url = {https://doi.org/10.1016/j.tibs.2020.12.005} } @article{choi2009-19837759, author = {Choi, SR. and Golding, G. and Zhuang, Z. and Zhang, W. and Lim, N. and Hefti, F. and Benedum, T. E. and Kilbourn, M. R. and others}, title = {{Preclinical properties of 18F-AV-45: a PET agent for Abeta plaques in the brain}}, journal = {Journal of nuclear medicine : official publication, Society of Nuclear Medicine}, year = {2009}, doi = {10.2967/jnumed.109.065284}, pmid = {19837759}, url = {https://doi.org/10.2967/jnumed.109.065284} } @article{kang2023-37725909, author = {Kang, J. H. and Korecka, M. and Lee, E. B. and Cousins, K. A. Q. and Tropea, T. F. and Chen-Plotkin, A. A. and Irwin, D. J. and Wolk, D. and others}, title = {{Alzheimer Disease Biomarkers: Moving from CSF to Plasma for Reliable Detection of Amyloid and tau Pathology}}, journal = {Clinical chemistry}, year = {2023}, doi = {10.1093/clinchem/hvad139}, pmid = {37725909}, url = {https://doi.org/10.1093/clinchem/hvad139} } @article{neumann2007-17279000, author = {Neumann, M. and Mackenzie, I. R. and Cairns, N. J. and Boyer, P. J. and Markesbery, W. R. and Smith, C. D. and Taylor, J. P. and Kretzschmar, H. A. and others}, title = {{TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations}}, journal = {Journal of neuropathology and experimental neurology}, year = {2007}, doi = {10.1097/nen.0b013e31803020b9}, pmid = {17279000}, url = {https://doi.org/10.1097/nen.0b013e31803020b9} } @article{uryu2002-11784789, author = {Uryu, K. and Laurer, H. and McIntosh, T. and Praticò, D. and Martinez, D. and Leight, S. and Lee, V. M. and Trojanowski, J. Q.}, title = {{Repetitive mild brain trauma accelerates Abeta deposition, lipid peroxidation, and cognitive impairment in a transgenic mouse model of Alzheimer amyloidosis}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2002}, doi = {10.1523/jneurosci.22-02-00446.2002}, pmid = {11784789}, url = {https://doi.org/10.1523/jneurosci.22-02-00446.2002} } @article{bagasra1996-8780811, author = {Bagasra, O. and Lavi, E. and Bobroski, L. and Khalili, K. and Pestaner, J. P. and Tawadros, R. and Pomerantz, R. J.}, title = {{Cellular reservoirs of HIV-1 in the central nervous system of infected individuals: identification by the combination of in situ polymerase chain reaction and immunohistochemistry}}, journal = {AIDS (London, England)}, year = {1996}, doi = {10.1097/00002030-199606000-00002}, pmid = {8780811}, url = {https://doi.org/10.1097/00002030-199606000-00002} } @article{carpenter2025-40820287, author = {Carpenter, Joan G. and Oduro, Elisha Baafi and Hodgson, Nancy A. and Zhu, Shijun and Gurlu, Merve and Ersek, Mary T. and Hanson, Laura C.}, title = {{Palliative Care Needs of Older Adults With and Without Dementia During Post-Acute Care in Skilled Nursing Facilities}}, journal = {Journal of Applied Gerontology}, year = {2025}, doi = {10.1177/07334648251363646}, pmid = {40820287}, url = {https://doi.org/10.1177/07334648251363646} } @article{gupta2024-03638dde, author = {Gupta, Ravi and Fein, Jay and Newhouse, Joseph P and Schwartz, Aaron L}, title = {{Comparison of prior authorization across insurers: cross sectional evidence from Medicare Advantage}}, journal = {BMJ}, year = {2024}, doi = {10.1136/bmj-2023-077797}, url = {https://doi.org/10.1136/bmj-2023-077797} } @article{doty2012-22584158, author = {Doty, R. L.}, title = {{Olfactory dysfunction in Parkinson disease}}, journal = {Nature reviews. Neurology}, year = {2012}, doi = {10.1038/nrneurol.2012.80}, pmid = {22584158}, url = {https://doi.org/10.1038/nrneurol.2012.80} } @article{irwin2018-30473927, author = {Irwin, D. J. and Hurtig, H. I.}, title = {{The Contribution of Tau, Amyloid-Beta and Alpha-Synuclein Pathology to Dementia in Lewy Body Disorders}}, journal = {Journal of Alzheimer's disease \& Parkinsonism}, year = {2018}, doi = {10.4172/2161-0460.1000444}, pmid = {30473927}, url = {https://doi.org/10.4172/2161-0460.1000444} } @article{boxer2020-31668596, author = {Boxer, A. L. and Gold, M. and Feldman, H. and Boeve, B. F. and Dickinson, S. L. and Fillit, H. and Ho, C. and Paul, R. and others}, title = {{New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2020}, doi = {10.1016/j.jalz.2019.06.4956}, pmid = {31668596}, url = {https://doi.org/10.1016/j.jalz.2019.06.4956} } @article{giannini2019-30851133, author = {Giannini, L. A. A. and Xie, S. X. and McMillan, C. T. and Liang, M. and Williams, A. and Jester, C. and Rascovsky, K. and Wolk, D. A. and others}, title = {{Divergent patterns of TDP-43 and tau pathologies in primary progressive aphasia}}, journal = {Annals of neurology}, year = {2019}, doi = {10.1002/ana.25465}, pmid = {30851133}, url = {https://doi.org/10.1002/ana.25465} } @article{blomeke2022-35655068, author = {Blömeke, L. and Pils, M. and Kraemer-Schulien, V. and Dybala, A. and Schaffrath, A. and Kulawik, A. and Rehn, F. and Cousin, A. and others}, title = {{Quantitative detection of α-Synuclein and Tau oligomers and other aggregates by digital single particle counting}}, journal = {NPJ Parkinson's disease}, year = {2022}, doi = {10.1038/s41531-022-00330-x}, pmid = {35655068}, url = {https://doi.org/10.1038/s41531-022-00330-x} } @article{paumier2015-26093169, author = {Paumier, K. L. and Luk, K. C. and Manfredsson, F. P. and Kanaan, N. M. and Lipton, J. W. and Collier, T. J. and Steece-Collier, K. and Kemp, C. J. and others}, title = {{Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration}}, journal = {Neurobiology of disease}, year = {2015}, doi = {10.1016/j.nbd.2015.06.003}, pmid = {26093169}, url = {https://doi.org/10.1016/j.nbd.2015.06.003} } @article{suarezcalvet2018-30482868, author = {Suárez-Calvet, M. and Capell, A. and MÁ, Araque Caballero and Morenas-Rodríguez, E. and Fellerer, K. and Franzmeier, N. and Kleinberger, G. and Eren, E. and others}, title = {{CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline}}, journal = {EMBO molecular medicine}, year = {2018}, doi = {10.15252/emmm.201809712}, pmid = {30482868}, url = {https://doi.org/10.15252/emmm.201809712} } @article{brettschneider2012-22210083, author = {Brettschneider, J. and Libon, D. J. and Toledo, J. B. and Xie, S. X. and McCluskey, L. and Elman, L. and Geser, F. and Lee, V. M. and others}, title = {{Microglial activation and TDP-43 pathology correlate with executive dysfunction in amyotrophic lateral sclerosis}}, journal = {Acta neuropathologica}, year = {2012}, doi = {10.1007/s00401-011-0932-x}, pmid = {22210083}, url = {https://doi.org/10.1007/s00401-011-0932-x} } @article{young2021-34458723, author = {Young, A. L. and Vogel, J. W. and Aksman, L. M. and Wijeratne, P. A. and Eshaghi, A. and Oxtoby, N. P. and Williams, S. C. R. and Alexander, D. C. and others}, title = {{Ordinal SuStaIn: Subtype and Stage Inference for Clinical Scores, Visual Ratings, and Other Ordinal Data}}, journal = {Frontiers in artificial intelligence}, year = {2021}, doi = {10.3389/frai.2021.613261}, pmid = {34458723}, url = {https://doi.org/10.3389/frai.2021.613261} } @article{ritson2010-20519548, author = {Ritson, G. P. and Custer, S. K. and Freibaum, B. D. and Guinto, J. B. and Geffel, D. and Moore, J. and Tang, W. and Winton, M. J. and others}, title = {{TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2010}, doi = {10.1523/jneurosci.5894-09.2010}, pmid = {20519548}, url = {https://doi.org/10.1523/jneurosci.5894-09.2010} } @article{bayram2025-39886324, author = {Bayram, Ece and Coughlin, David G. and Koga, Shunsuke and Ross, Owen A. and Litvan, Irene and Dickson, Dennis W.}, title = {{Sex differences for regional pathology in people with a high likelihood of Lewy body dementia phenotype based on underlying pathology}}, journal = {Alzheimer s \& Dementia Diagnosis Assessment \& Disease Monitoring}, year = {2025}, doi = {10.1002/dad2.70083}, pmid = {39886324}, url = {https://doi.org/10.1002/dad2.70083} } @article{ingraham2024-38975882, author = {Ingraham, B. C. and Barthold, D. and Coe, N. B. and Fishman, P.}, title = {{Medicare expenditures among spouses of persons with dementia}}, journal = {Journal of the American Geriatrics Society}, year = {2024}, doi = {10.1111/jgs.19074}, pmid = {38975882}, url = {https://doi.org/10.1111/jgs.19074} } @article{johnson2013-23809369, author = {Johnson, K. A. and Minoshima, S. and Bohnen, N. I. and Donohoe, K. J. and Foster, N. L. and Herscovitch, P. and Karlawish, J. H. and Rowe, C. C. and others}, title = {{Update on appropriate use criteria for amyloid PET imaging: dementia experts, mild cognitive impairment, and education. Amyloid Imaging Task Force of the Alzheimer’s Association and Society for Nuclear Medicine and Molecular Imaging}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2013}, doi = {10.1016/j.jalz.2013.06.001}, pmid = {23809369}, url = {https://doi.org/10.1016/j.jalz.2013.06.001} } @article{kovacs2017-28340083, author = {Kovacs, G. G. and Robinson, J. L. and Xie, S. X. and Lee, E. B. and Grossman, M. and Wolk, D. A. and Irwin, D. J. and Weintraub, D. and others}, title = {{Evaluating the Patterns of Aging-Related Tau Astrogliopathy Unravels Novel Insights Into Brain Aging and Neurodegenerative Diseases}}, journal = {Journal of neuropathology and experimental neurology}, year = {2017}, doi = {10.1093/jnen/nlx007}, pmid = {28340083}, url = {https://doi.org/10.1093/jnen/nlx007} } @article{peskind2006-16831961, author = {Peskind, E. R. and Li, G. and Shofer, J. and Quinn, J. F. and Kaye, J. A. and Clark, C. M. and Farlow, M. R. and DeCarli, C. and others}, title = {{Age and apolipoprotein E*4 allele effects on cerebrospinal fluid beta-amyloid 42 in adults with normal cognition}}, journal = {Archives of neurology}, year = {2006}, doi = {10.1001/archneur.63.7.936}, pmid = {16831961}, url = {https://doi.org/10.1001/archneur.63.7.936} } @article{karch2018-29630712, author = {Karch, C. M. and Wen, N. and Fan, C. C. and Yokoyama, J. S. and Kouri, N. and Ross, O. A. and Höglinger, G. and Müller, U. and others}, title = {{Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum}}, journal = {JAMA neurology}, year = {2018}, doi = {10.1001/jamaneurol.2018.0372}, pmid = {29630712}, url = {https://doi.org/10.1001/jamaneurol.2018.0372} } @article{chin2011-21399486, author = {Chin, A. L. and Negash, S. and Hamilton, R.}, title = {{Diversity and disparity in dementia: the impact of ethnoracial differences in Alzheimer disease}}, journal = {Alzheimer disease and associated disorders}, year = {2011}, doi = {10.1097/wad.0b013e318211c6c9}, pmid = {21399486}, url = {https://doi.org/10.1097/wad.0b013e318211c6c9} } @article{grossman2010-20139998, author = {Grossman, M.}, title = {{Primary progressive aphasia: clinicopathological correlations}}, journal = {Nature reviews. Neurology}, year = {2010}, doi = {10.1038/nrneurol.2009.216}, pmid = {20139998}, url = {https://doi.org/10.1038/nrneurol.2009.216} } @article{coskun2012-21871538, author = {Coskun, P. and Wyrembak, J. and Schriner, S. E. and Chen, H. W. and Marciniack, C. and Laferla, F. and Wallace, D. C.}, title = {{A mitochondrial etiology of Alzheimer and Parkinson disease}}, journal = {Biochimica et biophysica acta}, year = {2012}, doi = {10.1016/j.bbagen.2011.08.008}, pmid = {21871538}, url = {https://doi.org/10.1016/j.bbagen.2011.08.008} } @article{lippa2009-20008652, author = {Lippa, C. F. and Rosso, A. L. and Stutzbach, L. D. and Neumann, M. and Lee, V. M. and Trojanowski, J. Q.}, title = {{Transactive response DNA-binding protein 43 burden in familial Alzheimer disease and Down syndrome}}, journal = {Archives of neurology}, year = {2009}, doi = {10.1001/archneurol.2009.277}, pmid = {20008652}, url = {https://doi.org/10.1001/archneurol.2009.277} } @article{ramsey2007-17204939, author = {Ramsey, C. P. and Glass, C. A. and Montgomery, M. B. and Lindl, K. A. and Ritson, G. P. and Chia, L. A. and Hamilton, R. L. and Chu, C. T. and others}, title = {{Expression of Nrf2 in neurodegenerative diseases}}, journal = {Journal of neuropathology and experimental neurology}, year = {2007}, doi = {10.1097/nen.0b013e31802d6da9}, pmid = {17204939}, url = {https://doi.org/10.1097/nen.0b013e31802d6da9} } @article{galvin1999-10557341, author = {Galvin, J. E. and Uryu, K. and Lee, V. M. and Trojanowski, J. Q.}, title = {{Axon pathology in Parkinson's disease and Lewy body dementia hippocampus contains alpha-, beta-, and gamma-synuclein}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {1999}, doi = {10.1073/pnas.96.23.13450}, pmid = {10557341}, url = {https://doi.org/10.1073/pnas.96.23.13450} } @article{wiley2009-19139300, author = {Wiley, C. A. and Lopresti, B. J. and Venneti, S. and Price, J. and Klunk, W. E. and DeKosky, S. T. and Mathis, C. A.}, title = {{Carbon 11-labeled Pittsburgh Compound B and carbon 11-labeled (R)-PK11195 positron emission tomographic imaging in Alzheimer disease}}, journal = {Archives of neurology}, year = {2009}, doi = {10.1001/archneurol.2008.511}, pmid = {19139300}, url = {https://doi.org/10.1001/archneurol.2008.511} } @article{rosenthal2010-20310053, author = {Rosenthal, E. and Brennan, L. and Xie, S. and Hurtig, H. and Milber, J. and Weintraub, D. and Karlawish, J. and Siderowf, A.}, title = {{Association between cognition and function in patients with Parkinson disease with and without dementia}}, journal = {Movement disorders : official journal of the Movement Disorder Society}, year = {2010}, doi = {10.1002/mds.23073}, pmid = {20310053}, url = {https://doi.org/10.1002/mds.23073} } @article{wang2013-24179814, author = {Wang, Z. and Das, SR. and Xie, S. X. and Arnold, S. E. and Detre, J. A. and Wolk, D. A. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{Arterial spin labeled MRI in prodromal Alzheimer's disease: A multi-site study}}, journal = {NeuroImage. Clinical}, year = {2013}, doi = {10.1016/j.nicl.2013.04.014}, pmid = {24179814}, url = {https://doi.org/10.1016/j.nicl.2013.04.014} } @article{arnold2010-20437581, author = {Arnold, S. E. and Lee, E. B. and Moberg, P. J. and Stutzbach, L. and Kazi, H. and Han, L. Y. and Lee, V. M. and Trojanowski, J. Q.}, title = {{Olfactory epithelium amyloid-beta and paired helical filament-tau pathology in Alzheimer disease}}, journal = {Annals of neurology}, year = {2010}, doi = {10.1002/ana.21910}, pmid = {20437581}, url = {https://doi.org/10.1002/ana.21910} } @article{coe2020-32359073, author = {Coe, Norma B. and Van Houtven, Courtney H.}, title = {{Living Arrangements of Older Adults and COVID‐19 Risk: It Is Not Just Nursing Homes}}, journal = {Journal of the American Geriatrics Society}, year = {2020}, doi = {10.1111/jgs.16529}, pmid = {32359073}, url = {https://doi.org/10.1111/jgs.16529} } @article{berridge2025-40313054, author = {Berridge, Clara W. and Turner, Natalie R. and Lober, William B. and Demiris, George and JEFFREY A., K. A. Y. E.}, title = {{Sharing patient technology preferences with care networks: Stakeholders’ views of the “Let’s Talk Tech” decision aid for dementia care}}, journal = {Journal of Alzheimer s Disease}, year = {2025}, doi = {10.1177/13872877251332659}, pmid = {40313054}, url = {https://doi.org/10.1177/13872877251332659} } @article{reddy2025-40586237, author = {Reddy, Mallika and Li, June and Pajewski, Nicholas M. and Gaussoin, Sarah A. and Bryan, Robert Nick and Nasrallah, Ilya M. and Tamura, Manjula Kurella}, title = {{Cerebral small vessel disease and effects of intensive versus standard blood pressure treatment on cardiovascular outcomes and adverse events}}, journal = {Journal of Hypertension}, year = {2025}, doi = {10.1097/hjh.0000000000004093}, pmid = {40586237}, url = {https://doi.org/10.1097/hjh.0000000000004093} } @article{joshi2012-22331215, author = {Joshi, Abhinay D. and Pontecorvo, Michael J. and Clark, Chrisopher M. and Carpenter, Alan P. and Jennings, Danna L. and Sadowsky, Carl and Adler, Lee P. and Kovnat, Karel D. and Seibyl, John Peter and Arora, Anupa and Saha, Krishnendu and Burns, Jason and Lowrey, Mark J. and Mintun, Mark A. and Skovronsky, Daniel and {the Florbetapir F 18 Study Investigators}}, title = {{Performance Characteristics of Amyloid PET with Florbetapir F 18 in Patients with Alzheimer's Disease and Cognitively Normal Subjects}}, journal = {Journal of Nuclear Medicine}, year = {2012}, doi = {10.2967/jnumed.111.090340}, pmid = {22331215}, url = {https://doi.org/10.2967/jnumed.111.090340} } @article{jun2012-22869155, author = {Jun, G. and Vardarajan, B. N. and Buros, J. and Yu, C. E. and Hawk, M. V. and Dombroski, B. A. and Crane, P. K. and Larson, E. B. and others}, title = {{Comprehensive search for Alzheimer disease susceptibility loci in the APOE region}}, journal = {Archives of neurology}, year = {2012}, doi = {10.1001/archneurol.2012.2052}, pmid = {22869155}, url = {https://doi.org/10.1001/archneurol.2012.2052} } @article{smith1999-10499440, author = {Smith, D. H. and Chen, X. H. and Nonaka, M. and Trojanowski, J. Q. and Lee, V. M. and Saatman, K. E. and Leoni, M. J. and Xu, B. N. and others}, title = {{Accumulation of amyloid beta and tau and the formation of neurofilament inclusions following diffuse brain injury in the pig}}, journal = {Journal of neuropathology and experimental neurology}, year = {1999}, doi = {10.1097/00005072-199909000-00008}, pmid = {10499440}, url = {https://doi.org/10.1097/00005072-199909000-00008} } @article{gandy2010-20641005, author = {Gandy, S. and Simon, A. J. and Steele, J. W. and Lublin, A. L. and Lah, J. J. and Walker, L. C. and Levey, A. I. and Krafft, G. A. and others}, title = {{Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomers}}, journal = {Annals of neurology}, year = {2010}, doi = {10.1002/ana.22052}, pmid = {20641005}, url = {https://doi.org/10.1002/ana.22052} } @article{nam2017-28655926, author = {Nam, K. N. and Mounier, A. and Wolfe, C. M. and Fitz, N. F. and Carter, A. Y. and Castranio, E. L. and Kamboh, H. I. and Reeves, V. L. and others}, title = {{Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer's model mice}}, journal = {Scientific reports}, year = {2017}, doi = {10.1038/s41598-017-04412-2}, pmid = {28655926}, url = {https://doi.org/10.1038/s41598-017-04412-2} } @article{ono2025-40042515, author = {Ono, Daisuke and Sekiya, Hiroaki and Maier, Alexia R. and Murray, Melissa Erin and Koga, Shunsuke and Dickson, Dennis W.}, title = {{Parkinsonism in Alzheimer's disease without Lewy bodies in association with nigral neuron loss: A data‐driven clinicopathologic study}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.14628}, pmid = {40042515}, url = {https://doi.org/10.1002/alz.14628} } @article{anagnostakis2025-40951936, author = {Anagnostakis, Filippos and Kokkorakis, Michail and Asvestis, Christos and Papadimopoulos, Ilias and Nagarajan, Shrihari and Talbot, Konrad and Li, Lu and Chen, Yong and others}, title = {{Impact of cardiometabolic conditions on the progression from mild cognitive impairment to dementia: A large cohort study}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70692}, pmid = {40951936}, url = {https://doi.org/10.1002/alz.70692} } @article{lu2025-41277110, author = {Lu, Jiayi and Di Florio, Damian Nicolas and Boya, Patricia and Maday, Sandra and Springer, Wolfdieter and Chu, Charleen T.}, title = {{Autophagy and mitophagy at the synapse and beyond: implications for learning, memory and neurological disorders}}, journal = {Autophagy}, year = {2025}, doi = {10.1080/15548627.2025.2581217}, pmid = {41277110}, url = {https://doi.org/10.1080/15548627.2025.2581217} } @article{katsumi2025-39968692, author = {Katsumi, Yuta and Touroutoglou, Alexandra and Brickhouse, Michael J. and Eloyan, Ani and Eckbo, Ryan and Zaitsev, Alexander and La Joie, Renaud and Lagarde, Julien and others}, title = {{Dissociable spatial topography of cortical atrophy in early‐onset and late‐onset Alzheimer's disease: A head‐to‐head comparison of the LEADS and ADNI cohorts}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.14489}, pmid = {39968692}, url = {https://doi.org/10.1002/alz.14489} } @article{chen2026-dd40034c, author = {Chen, Robin and Chiu, Shannon and DeSimone, Jesse C. and Wang, Wei and Barmpoutis, Angelos and McMillan, Corey T. and Radhakrishnan, Hamsanandini and Irwin, David John and others}, title = {{Automated Imaging Differentiation for Dementia}}, journal = {Neurology Open Access}, year = {2026}, doi = {10.1212/wn9.0000000000000093}, url = {https://doi.org/10.1212/wn9.0000000000000093} } @article{johnson2013-23753186, author = {Johnson, K. A. and Minoshima, S. and Bohnen, N. I. and Donohoe, K. J. and Foster, N. L. and Herscovitch, P. and Karlawish, J. H. and Rowe, C. C. and others}, title = {{Update on appropriate use criteria for amyloid PET imaging: dementia experts, mild cognitive impairment, and education}}, journal = {Journal of nuclear medicine : official publication, Society of Nuclear Medicine}, year = {2013}, doi = {10.2967/jnumed.113.127068}, pmid = {23753186}, url = {https://doi.org/10.2967/jnumed.113.127068} } @article{bis2020-30108311, author = {Bis, J. C. and Jian, X. and Kunkle, B. W. and Chen, Y. and Hamilton-Nelson, K. L. and Bush, W. S. and Salerno, W. J. and Lancour, D. and others}, title = {{Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation}}, journal = {Molecular psychiatry}, year = {2020}, doi = {10.1038/s41380-018-0112-7}, pmid = {30108311}, url = {https://doi.org/10.1038/s41380-018-0112-7} } @article{palmer2013-23498384, author = {Palmer, B. W. and Ryan, K. A. and Kim, H. M. and Karlawish, J. H. and Appelbaum, P. S. and Kim, S. Y.}, title = {{Neuropsychological correlates of capacity determinations in Alzheimer disease: implications for assessment}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2013}, doi = {10.1016/j.jagp.2012.11.008}, pmid = {23498384}, url = {https://doi.org/10.1016/j.jagp.2012.11.008} } @article{grossman2007-17998442, author = {Grossman, M. and Libon, D. J. and Forman, M. S. and Massimo, L. and Wood, E. and Moore, P. and Anderson, C. and Farmer, J. and others}, title = {{Distinct antemortem profiles in patients with pathologically defined frontotemporal dementia}}, journal = {Archives of neurology}, year = {2007}, doi = {10.1001/archneur.64.11.1601}, pmid = {17998442}, url = {https://doi.org/10.1001/archneur.64.11.1601} } @article{tu1996-8610185, author = {Tu, P. H. and Raju, P. and Robinson, K. A. and Gurney, M. E. and Trojanowski, J. Q. and Lee, V. M.}, title = {{Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {1996}, doi = {10.1073/pnas.93.7.3155}, pmid = {8610185}, url = {https://doi.org/10.1073/pnas.93.7.3155} } @article{wolf1995-7876266, author = {Wolf, B. A. and Wertkin, A. M. and Jolly, Y. C. and Yasuda, R. P. and Wolfe, B. B. and Konrad, R. J. and Manning, D. and Ravi, S. and others}, title = {{Muscarinic regulation of Alzheimer's disease amyloid precursor protein secretion and amyloid beta-protein production in human neuronal NT2N cells}}, journal = {The Journal of biological chemistry}, year = {1995}, doi = {10.1074/jbc.270.9.4916}, pmid = {7876266}, url = {https://doi.org/10.1074/jbc.270.9.4916} } @article{irwin2013-23885714, author = {Irwin, D. J. and Cohen, T. J. and Grossman, M. and Arnold, S. E. and McCarty-Wood, E. and Van Deerlin, V. M. and Lee, V. M. and Trojanowski, J. Q.}, title = {{Acetylated tau neuropathology in sporadic and hereditary tauopathies}}, journal = {The American journal of pathology}, year = {2013}, doi = {10.1016/j.ajpath.2013.04.025}, pmid = {23885714}, url = {https://doi.org/10.1016/j.ajpath.2013.04.025} } @article{arai1990-1690426, author = {Arai, H. and Lee, V. M. and Otvos, L. and Greenberg, B. D. and Lowery, D. E. and Sharma, S. K. and Schmidt, M. L. and Trojanowski, J. Q.}, title = {{Defined neurofilament, tau, and beta-amyloid precursor protein epitopes distinguish Alzheimer from non-Alzheimer senile plaques}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {1990}, doi = {10.1073/pnas.87.6.2249}, pmid = {1690426}, url = {https://doi.org/10.1073/pnas.87.6.2249} } @article{irwin2012-22490326, author = {Irwin, D. J. and McMillan, C. T. and Toledo, J. B. and Arnold, S. E. and Shaw, L. M. and Wang, L. S. and Van Deerlin, V. and Lee, V. M. and others}, title = {{Comparison of cerebrospinal fluid levels of tau and Aβ 1-42 in Alzheimer disease and frontotemporal degeneration using 2 analytical platforms}}, journal = {Archives of neurology}, year = {2012}, doi = {10.1001/archneurol.2012.26}, pmid = {22490326}, url = {https://doi.org/10.1001/archneurol.2012.26} } @article{mcmillan2013-23269595, author = {McMillan, C. T. and Avants, B. and Irwin, D. J. and Toledo, J. B. and Wolk, D. A. and Van Deerlin, V. M. and Shaw, L. M. and Trojanoswki, J. Q. and others}, title = {{Can MRI screen for CSF biomarkers in neurodegenerative disease?}}, journal = {Neurology}, year = {2013}, doi = {10.1212/wnl.0b013e31827b9147}, pmid = {23269595}, url = {https://doi.org/10.1212/wnl.0b013e31827b9147} } @article{wang2010-20709038, author = {Wang, J. and Eslinger, P. J. and Doty, R. L. and Zimmerman, E. K. and Grunfeld, R. and Sun, X. and Meadowcroft, M. D. and Connor, JR. and others}, title = {{Olfactory deficit detected by fMRI in early Alzheimer's disease}}, journal = {Brain research}, year = {2010}, doi = {10.1016/j.brainres.2010.08.018}, pmid = {20709038}, url = {https://doi.org/10.1016/j.brainres.2010.08.018} } @article{sunkureddi2018-29449495, author = {Sunkureddi, Prashanth R. and Doogan, Stephen and Heid, John and Benosman, Samir and Ogdie, Alexis and Martin, Layne and Palmer, Jacqueline B.}, title = {{Evaluation of Self-reported Patient Experiences: Insights from Digital Patient Communities in Psoriatic Arthritis}}, journal = {The Journal of Rheumatology}, year = {2018}, doi = {10.3899/jrheum.170500}, pmid = {29449495}, url = {https://doi.org/10.3899/jrheum.170500} } @article{li2026-755a93c8, author = {Li, Yiting and Menon, Gayathri and Long, Jane J. and Kim, Byoungjun and Bae, Sunjae and Orandi, Babak John and DeMarco, Mario P. and Wu, Wenbo and others}, title = {{Neighborhood Disadvantage and Dementia Risk Among Older Patients With Kidney Failure: Differences by Race/Ethnicity and Urbanicity}}, journal = {Kidney Medicine}, year = {2026}, doi = {10.1016/j.xkme.2026.101479}, url = {https://doi.org/10.1016/j.xkme.2026.101479} } @article{mozersky2025-40342234, author = {Mozersky, Jessica T. and Assfaw, Araya Dimtsu and Berry, Joyce E. Balls and Moulder, Krista L. and Denny, Andrea and Aranda, María and Asthana, Sanjay and Babulal, Ganesh Muneshwar and others}, title = {{Enhancing participation of historically minoritized groups in Alzheimer disease and related dementias research: National Conference Report}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70168}, pmid = {40342234}, url = {https://doi.org/10.1002/alz.70168} } @article{kashyap2025-40199828, author = {Kashyap, Aditya M and Rao, Delip and Boland, Mary Regina and Shen, Li and Callison-Burch, Chris}, title = {{Predicting explainable dementia types with LLM-aided feature engineering}}, journal = {Bioinformatics}, year = {2025}, doi = {10.1093/bioinformatics/btaf156}, pmid = {40199828}, url = {https://doi.org/10.1093/bioinformatics/btaf156} } @article{maust2025-40888611, author = {Maust, Donovan T. and Wagner, James R. and Zimmerman, Sheryl Itkin and Wagner, Laura M. and Marcus, Steven C. and White, Elizabeth M. and Tocco, Rachel S. and Rothstein, Joanie and others}, title = {{The National Dementia Workforce Study: Overview}}, journal = {Journal of the American Geriatrics Society}, year = {2025}, doi = {10.1111/jgs.70061}, pmid = {40888611}, url = {https://doi.org/10.1111/jgs.70061} } @article{mohs1997-37e2cc49, author = {Mohs, Richard C. and Knopman, David S. and Petersen, Ronald Carl and Ferris, Steven H. and Ernesto, Chris and Grundman, Michael and Sano, Mary and Bieliauskas, Linas A. and Geldmacher, David and Clark, Chris M. and Thal, Leon J.}, title = {{Development of Cognitive Instruments for Use in Clinical Trials of Antidementia Drugs}}, journal = {Alzheimer Disease \& Associated Disorders}, year = {1997}, doi = {10.1097/00002093-199700112-00003}, url = {https://doi.org/10.1097/00002093-199700112-00003} } @article{arias2014-24477112, author = {Arias, J. J. and Karlawish, J.}, title = {{Confidentiality in preclinical Alzheimer disease studies: when research and medical records meet}}, journal = {Neurology}, year = {2014}, doi = {10.1212/wnl.0000000000000153}, pmid = {24477112}, url = {https://doi.org/10.1212/wnl.0000000000000153} } @article{gallo1999-10478901, author = {Gallo, J. J. and Lebowitz, B. D.}, title = {{The epidemiology of common late-life mental disorders in the community: themes for the new century}}, journal = {Psychiatric services (Washington, D.C.)}, year = {1999}, doi = {10.1176/ps.50.9.1158}, pmid = {10478901}, url = {https://doi.org/10.1176/ps.50.9.1158} } @article{ash2012-22099969, author = {Ash, S. and McMillan, C. and Gross, R. G. and Cook, P. and Gunawardena, D. and Morgan, B. and Boller, A. and Siderowf, A. and others}, title = {{Impairments of speech fluency in Lewy body spectrum disorder}}, journal = {Brain and language}, year = {2012}, doi = {10.1016/j.bandl.2011.09.004}, pmid = {22099969}, url = {https://doi.org/10.1016/j.bandl.2011.09.004} } @article{chen2010-20382237, author = {Chen, R. and Herskovits, E. H.}, title = {{Machine-learning techniques for building a diagnostic model for very mild dementia}}, journal = {NeuroImage}, year = {2010}, doi = {10.1016/j.neuroimage.2010.03.084}, pmid = {20382237}, url = {https://doi.org/10.1016/j.neuroimage.2010.03.084} } @article{higgins2026-40903895, author = {Higgins, A. and Tewolde, S. and Page, S. D. and Rubenstein, E.}, title = {{The Occurrence of Obstructive Sleep Apnea and Its Association With Alzheimer Dementia in Medicaid-Enrolled Adults With Down Syndrome, 2011-2019}}, journal = {American journal of medical genetics. Part A}, year = {2026}, doi = {10.1002/ajmg.a.64241}, pmid = {40903895}, url = {https://doi.org/10.1002/ajmg.a.64241} } @article{tang2011-21857497, author = {Tang, J. X. and Baranov, D. and Hammond, M. and Shaw, L. M. and Eckenhoff, M. F. and Eckenhoff, R. G.}, title = {{Human Alzheimer and inflammation biomarkers after anesthesia and surgery}}, journal = {Anesthesiology}, year = {2011}, doi = {10.1097/aln.0b013e31822e9306}, pmid = {21857497}, url = {https://doi.org/10.1097/aln.0b013e31822e9306} } @article{nettiksimmons2010-20542598, author = {Nettiksimmons, J. and Harvey, D. and Brewer, J. and Carmichael, O. and DeCarli, C. and Jack, C. R. and Petersen, R. and Shaw, L. M. and others}, title = {{Subtypes based on cerebrospinal fluid and magnetic resonance imaging markers in normal elderly predict cognitive decline}}, journal = {Neurobiology of aging}, year = {2010}, doi = {10.1016/j.neurobiolaging.2010.04.025}, pmid = {20542598}, url = {https://doi.org/10.1016/j.neurobiolaging.2010.04.025} } @article{albright1999-9847323, author = {Albright, A. V. and Shieh, J. T. and Itoh, T. and Lee, B. and Pleasure, D. and O'Connor, M. J. and Doms, R. W. and González-Scarano, F.}, title = {{Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates}}, journal = {Journal of virology}, year = {1999}, doi = {10.1128/jvi.73.1.205-213.1999}, pmid = {9847323}, url = {https://doi.org/10.1128/jvi.73.1.205-213.1999} } @article{boyle2025-41346478, author = {Boyle, Rory Thomas and Dehghani, Nadia and Emrani, Sheina and Wadhwani, Anil R. and Matyi, Melanie A. and Cousins, Katheryn A Q and Rhodes, Emma and Nelson, Sacha B. and others}, title = {{Higher neighborhood deprivation is associated with accelerated disease progression in behavioral‐variant frontotemporal degeneration}}, journal = {Alzheimer s \& Dementia Behavior \& Socioeconomics of Aging}, year = {2025}, doi = {10.1002/bsa3.70045}, pmid = {41346478}, url = {https://doi.org/10.1002/bsa3.70045} }