% alzhub.org library filter % Source: https://alzhub.org/research?institution=I45129253 % 500 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{chatterjee2016-26681727, author = {Chatterjee, S. and Peters, S. A. and Woodward, M. and Mejia Arango, S. and Batty, G. D. and Beckett, N. and Beiser, A. and Borenstein, A. R. and others}, title = {{Type 2 Diabetes as a Risk Factor for Dementia in Women Compared With Men: A Pooled Analysis of 2.3 Million People Comprising More Than 100,000 Cases of Dementia}}, journal = {Diabetes care}, year = {2016}, doi = {10.2337/dc15-1588}, pmid = {26681727}, url = {https://doi.org/10.2337/dc15-1588} } @article{salloway2014-24450891, author = {Salloway, S. and Sperling, R. and Fox, N. C. and Blennow, K. and Klunk, W. and Raskind, M. and Sabbagh, M. and Honig, L. S. and others}, title = {{Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease}}, journal = {The New England journal of medicine}, year = {2014}, doi = {10.1056/nejmoa1304839}, pmid = {24450891}, url = {https://doi.org/10.1056/nejmoa1304839} } @article{kunkle2019-30820047, author = {Kunkle, B. W. and Grenier-Boley, B. and Sims, R. and Bis, J. C. and Damotte, V. and Naj, A. C. and Boland, A. and Vronskaya, M. and others}, title = {{Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing}}, journal = {Nature genetics}, year = {2019}, doi = {10.1038/s41588-019-0358-2}, pmid = {30820047}, url = {https://doi.org/10.1038/s41588-019-0358-2} } @article{guerreiro2013-23150934, author = {Guerreiro, R. and Wojtas, A. and Bras, J. and Carrasquillo, M. and Rogaeva, E. and Majounie, E. and Cruchaga, C. and Sassi, C. and others}, title = {{TREM2 variants in Alzheimer's disease}}, journal = {The New England journal of medicine}, year = {2013}, doi = {10.1056/nejmoa1211851}, pmid = {23150934}, url = {https://doi.org/10.1056/nejmoa1211851} } @article{ashton2024-38252443, author = {Ashton, N. J. and Brum, W. S. and Di Molfetta, G. and Benedet, A. L. and Arslan, B. and Jonaitis, E. and Langhough, R. E. and Cody, K. and Wilson, R. and Carlsson, C. M. and Vanmechelen, E. and Montoliu-Gaya, L. and others}, title = {{Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease Pathology}}, journal = {JAMA Neurology}, year = {2024}, doi = {10.1001/jamaneurol.2023.5319}, pmid = {38252443}, url = {https://doi.org/10.1001/jamaneurol.2023.5319} } @article{salloway2022-34807243, author = {Salloway, S. and Chalkias, S. and Barkhof, F. and Burkett, P. and Barakos, J. and Purcell, D. and Suhy, J. and Forrestal, F. and others}, title = {{Amyloid-Related Imaging Abnormalities in 2 Phase 3 Studies Evaluating Aducanumab in Patients With Early Alzheimer Disease}}, journal = {JAMA neurology}, year = {2022}, doi = {10.1001/jamaneurol.2021.4161}, pmid = {34807243}, url = {https://doi.org/10.1001/jamaneurol.2021.4161} } @article{buddhaeberlein2022-35542991, author = {Budd Haeberlein, S. and Aisen, P. S. and Barkhof, F. and Chalkias, S. and Chen, T. and Cohen, S. and Dent, G. and Hansson, O. and others}, title = {{Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer's Disease}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2022}, doi = {10.14283/jpad.2022.30}, pmid = {35542991}, url = {https://doi.org/10.14283/jpad.2022.30} } @article{naj2011-21460841, author = {Naj, A. C. and Jun, G. and Beecham, G. W. and Wang, L. S. and Vardarajan, B. N. and Buros, J. and Gallins, P. J. and Buxbaum, J. D. and others}, title = {{Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease}}, journal = {Nature genetics}, year = {2011}, doi = {10.1038/ng.801}, pmid = {21460841}, url = {https://doi.org/10.1038/ng.801} } @article{olsson2016-27068280, author = {Olsson, B. and Lautner, R. and Andreasson, U. and Öhrfelt, A. and Portelius, E. and Bjerke, M. and Hölttä, M. and Rosén, C. and others}, title = {{CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis}}, journal = {The Lancet. Neurology}, year = {2016}, doi = {10.1016/s1474-4422(16)00070-3}, pmid = {27068280}, url = {https://doi.org/10.1016/s1474-4422(16)00070-3} } @article{bateman2023-37966285, author = {Bateman, R. J. and Smith, J. and Donohue, M. C. and Delmar, P. and Abbas, R. and Salloway, S. and Wojtowicz, J. and Blennow, K. and others}, title = {{Two Phase 3 Trials of Gantenerumab in Early Alzheimer's Disease}}, journal = {The New England journal of medicine}, year = {2023}, doi = {10.1056/nejmoa2304430}, pmid = {37966285}, url = {https://doi.org/10.1056/nejmoa2304430} } @article{moayyedi2019-31152740, author = {Moayyedi, P. and Eikelboom, J. W. and Bosch, J. and Connolly, S. J. and Dyal, L. and Shestakovska, O. and Leong, D. and Anand, S. S. and others}, title = {{Safety of Proton Pump Inhibitors Based on a Large, Multi-Year, Randomized Trial of Patients Receiving Rivaroxaban or Aspirin}}, journal = {Gastroenterology}, year = {2019}, doi = {10.1053/j.gastro.2019.05.056}, pmid = {31152740}, url = {https://doi.org/10.1053/j.gastro.2019.05.056} } @article{kivimaki2019-30995986, author = {Kivimäki, M. and Singh-Manoux, A. and Pentti, J. and Sabia, S. and Nyberg, S. T. and Alfredsson, L. and Goldberg, M. and Knutsson, A. and others}, title = {{Physical inactivity, cardiometabolic disease, and risk of dementia: an individual-participant meta-analysis}}, journal = {BMJ (Clinical research ed.)}, year = {2019}, doi = {10.1136/bmj.l1495}, pmid = {30995986}, url = {https://doi.org/10.1136/bmj.l1495} } @article{bellaver2023-37248300, author = {Bellaver, B. and Povala, G. and Ferreira, P. C. L. and Ferrari-Souza, J. P. and Leffa, D. T. and Lussier, F. Z. and Benedet, A. L. and Ashton, N. J. and Triana-Baltzer, G. and Kolb, H. C. and Tissot, C. and Therriault, J. and others}, title = {{Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer's disease}}, journal = {Nature Medicine}, year = {2023}, doi = {10.1038/s41591-023-02380-x}, pmid = {37248300}, url = {https://doi.org/10.1038/s41591-023-02380-x} } @article{wightman2021-34493870, author = {Wightman, D. P. and Jansen, I. E. and Savage, J. E. and Shadrin, A. A. and Bahrami, S. and Holland, D. and Rongve, A. and Børte, S. and others}, title = {{A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease}}, journal = {Nature genetics}, year = {2021}, doi = {10.1038/s41588-021-00921-z}, pmid = {34493870}, url = {https://doi.org/10.1038/s41588-021-00921-z} } @article{blazhenets2026-42441390, author = {Blazhenets, Ganna and Soleimani-Meigooni, David N and Chiotis, Konstantinos and Allen, Isabel E and Rabinovici, Gil D and La Joie, Renaud and {Meta-Centiloid Study Group} and Apostolova, Liana G and others}, title = {{Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis}}, journal = {JAMA}, year = {2026}, doi = {10.1001/jama.2026.13116}, pmid = {42441390}, url = {https://doi.org/10.1001/jama.2026.13116} } @article{warmenhoven2025-39468767, author = {Warmenhoven, N. and Salvadó, G. and Janelidze, S. and Mattsson-Carlgren, N. and Bali, D. and Orduña Dolado, A. and Kolb, H. and Triana-Baltzer, G. and Barthélemy, N. R. and Schindler, S. E. and Aschenbrenner, A. J. and Raji, C. A. and others}, title = {{A comprehensive head-to-head comparison of key plasma phosphorylated tau 217 biomarker tests}}, journal = {Brain}, year = {2025}, doi = {10.1093/brain/awae346}, pmid = {39468767}, url = {https://doi.org/10.1093/brain/awae346} } @article{mattssoncarlgren2023-36745413, author = {Mattsson-Carlgren, N. and Salvadó, G. and Ashton, N. J. and Tideman, P. and Stomrud, E. and Zetterberg, H. and Ossenkoppele, R. and Betthauser, T. J. and others}, title = {{Prediction of Longitudinal Cognitive Decline in Preclinical Alzheimer Disease Using Plasma Biomarkers}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2022.5272}, pmid = {36745413}, url = {https://doi.org/10.1001/jamaneurol.2022.5272} } @article{jun2016-25778476, author = {Jun, G. and Ibrahim-Verbaas, C. A. and Vronskaya, M. and Lambert, J. C. and Chung, J. and Naj, A. C. and Kunkle, B. W. and Wang, L. S. and others}, title = {{A novel Alzheimer disease locus located near the gene encoding tau protein}}, journal = {Molecular psychiatry}, year = {2016}, doi = {10.1038/mp.2015.23}, pmid = {25778476}, url = {https://doi.org/10.1038/mp.2015.23} } @article{howard2020-31738372, author = {Howard, R. and Zubko, O. and Bradley, R. and Harper, E. and Pank, L. and O'Brien, J. and Fox, C. and Tabet, N. and others}, title = {{Minocycline at 2 Different Dosages vs Placebo for Patients With Mild Alzheimer Disease: A Randomized Clinical Trial}}, journal = {JAMA neurology}, year = {2020}, doi = {10.1001/jamaneurol.2019.3762}, pmid = {31738372}, url = {https://doi.org/10.1001/jamaneurol.2019.3762} } @article{bateman2012-22784036, author = {Bateman, Randall John and Xiong, Chengjie and Benzinger, Tammie L.S. and Fagan, Anne M. and Goate, Alison and Fox, Nick C. and Marcus, Daniel S. and Cairns, Nigel J. and others}, title = {{Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease}}, journal = {New England Journal of Medicine}, year = {2012}, doi = {10.1056/nejmoa1202753}, pmid = {22784036}, url = {https://doi.org/10.1056/nejmoa1202753} } @article{edison2025-41326666, author = {Edison, P. and Femminella, G. D. and Ritchie, C. and Nowell, J. and Holmes, C. and Walker, Z. and Ridha, B. and Raza, S. and Livingston, N. R. and Frangou, E. and others}, title = {{Liraglutide in mild to moderate Alzheimer's disease: a phase 2b clinical trial}}, journal = {Nature Medicine}, year = {2025}, doi = {10.1038/s41591-025-04106-7}, pmid = {41326666}, url = {https://doi.org/10.1038/s41591-025-04106-7} } @article{ayton2025-39495531, author = {Ayton, S. and Barton, D. and Brew, B. and Brodtmann, A. and Clarnette, R. and Desmond, P. and Devos, D. and Ellis, K. A. and others}, title = {{Deferiprone in Alzheimer Disease: A Randomized Clinical Trial}}, journal = {JAMA neurology}, year = {2025}, doi = {10.1001/jamaneurol.2024.3733}, pmid = {39495531}, url = {https://doi.org/10.1001/jamaneurol.2024.3733} } @article{lourida2019-31302669, author = {Lourida, I. and Hannon, E. and Littlejohns, T. J. and Langa, K. M. and Hyppönen, E. and Kuzma, E. and Llewellyn, D. J.}, title = {{Association of Lifestyle and Genetic Risk With Incidence of Dementia}}, journal = {JAMA}, year = {2019}, doi = {10.1001/jama.2019.9879}, pmid = {31302669}, url = {https://doi.org/10.1001/jama.2019.9879} } @article{karikari2020-32333900, author = {Karikari, T. K. and Pascoal, T. A. and Ashton, N. J. and Janelidze, S. and Benedet, A. L. and Rodriguez, J. L. and Chamoun, M. and Savard, M. and others}, title = {{Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts}}, journal = {The Lancet. Neurology}, year = {2020}, doi = {10.1016/s1474-4422(20)30071-5}, pmid = {32333900}, url = {https://doi.org/10.1016/s1474-4422(20)30071-5} } @article{emre2004-15590953, author = {Emre, M. and Aarsland, D. and Albanese, A. and Byrne, E. J. and Deuschl, G. and De Deyn, P. P. and Durif, F. and Kulisevsky, J. and others}, title = {{Rivastigmine for dementia associated with Parkinson's disease}}, journal = {The New England journal of medicine}, year = {2004}, doi = {10.1056/nejmoa041470}, pmid = {15590953}, url = {https://doi.org/10.1056/nejmoa041470} } @article{ostrowitzki2017-29221491, author = {Ostrowitzki, S. and Lasser, R. A. and Dorflinger, E. and Scheltens, P. and Barkhof, F. and Nikolcheva, T. and Ashford, E. and Retout, S. and others}, title = {{A phase III randomized trial of gantenerumab in prodromal Alzheimer's disease}}, journal = {Alzheimer's research \& therapy}, year = {2017}, doi = {10.1186/s13195-017-0318-y}, pmid = {29221491}, url = {https://doi.org/10.1186/s13195-017-0318-y} } @article{ferrari2014-24943344, author = {Ferrari, R. and Hernandez, D. G. and Nalls, M. A. and Rohrer, J. D. and Ramasamy, A. and Kwok, J. B. and Dobson-Stone, C. and Brooks, W. S. and others}, title = {{Frontotemporal dementia and its subtypes: a genome-wide association study}}, journal = {The Lancet. Neurology}, year = {2014}, doi = {10.1016/s1474-4422(14)70065-1}, pmid = {24943344}, url = {https://doi.org/10.1016/s1474-4422(14)70065-1} } @article{pereira2021-34259835, author = {Pereira, J. B. and Janelidze, S. and Smith, R. and Mattsson-Carlgren, N. and Palmqvist, S. and Teunissen, C. E. and Zetterberg, H. and Stomrud, E. and others}, title = {{Plasma GFAP is an early marker of amyloid-β but not tau pathology in Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2021}, doi = {10.1093/brain/awab223}, pmid = {34259835}, url = {https://doi.org/10.1093/brain/awab223} } @article{palmqvist2020-32722745, author = {Palmqvist, S. and Janelidze, S. and Quiroz, Y. T. and Zetterberg, H. and Lopera, F. and Stomrud, E. and Su, Y. and Chen, Y. and others}, title = {{Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders}}, journal = {JAMA}, year = {2020}, doi = {10.1001/jama.2020.12134}, pmid = {32722745}, url = {https://doi.org/10.1001/jama.2020.12134} } @article{salloway2025-39556389, author = {Salloway, S. and Wojtowicz, J. and Voyle, N. and Lane, C. A. and Klein, G. and Lyons, M. and Rossomanno, S. and Mazzo, F. and others}, title = {{Amyloid-Related Imaging Abnormalities (ARIA) in Clinical Trials of Gantenerumab in Early Alzheimer Disease}}, journal = {JAMA neurology}, year = {2025}, doi = {10.1001/jamaneurol.2024.3937}, pmid = {39556389}, url = {https://doi.org/10.1001/jamaneurol.2024.3937} } @article{gordon2018-29397305, author = {Gordon, B. A. and Blazey, T. M. and Su, Y. and Hari-Raj, A. and Dincer, A. and Flores, S. and Christensen, J. and McDade, E. and others}, title = {{Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study}}, journal = {The Lancet. Neurology}, year = {2018}, doi = {10.1016/s1474-4422(18)30028-0}, pmid = {29397305}, url = {https://doi.org/10.1016/s1474-4422(18)30028-0} } @article{oh2025-40164724, author = {Oh, H. S. and Urey, D. Y. and Karlsson, L. and Zhu, Z. and Shen, Y. and Farinas, A. and Timsina, J. and Duggan, M. R. and others}, title = {{A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer's disease}}, journal = {Nature medicine}, year = {2025}, doi = {10.1038/s41591-025-03565-2}, pmid = {40164724}, url = {https://doi.org/10.1038/s41591-025-03565-2} } @article{barbielliniamidei2021-33904867, author = {Barbiellini Amidei, C. and Fayosse, A. and Dumurgier, J. and Machado-Fragua, M. D. and Tabak, A. G. and van Sloten, T. and Kivimäki, M. and Dugravot, A. and others}, title = {{Association Between Age at Diabetes Onset and Subsequent Risk of Dementia}}, journal = {JAMA}, year = {2021}, doi = {10.1001/jama.2021.4001}, pmid = {33904867}, url = {https://doi.org/10.1001/jama.2021.4001} } @article{pascoal2021-34446931, author = {Pascoal, T. A. and Benedet, A. L. and Ashton, N. J. and Kang, M. S. and Therriault, J. and Chamoun, M. and Savard, M. and Lussier, F. Z. and others}, title = {{Microglial activation and tau propagate jointly across Braak stages}}, journal = {Nature medicine}, year = {2021}, doi = {10.1038/s41591-021-01456-w}, pmid = {34446931}, url = {https://doi.org/10.1038/s41591-021-01456-w} } @article{wang2025-40172303, author = {Wang, H. and Serap Monkul Nery, E. and Ardayfio, P. and Khanna, R. and Otero Svaldi, D. and Gueorguieva, I. and Shcherbinin, S. and Andersen, S. W. and Hauck, P. M. and Engle, S. E. and others}, title = {{Modified titration of donanemab reduces ARIA risk and maintains amyloid reduction}}, journal = {Alzheimer's \& Dementia}, year = {2025}, doi = {10.1002/alz.70062}, pmid = {40172303}, url = {https://doi.org/10.1002/alz.70062} } @article{mattsson2019-31009028, author = {Mattsson, N. and Cullen, N. C. and Andreasson, U. and Zetterberg, H. and Blennow, K.}, title = {{Association Between Longitudinal Plasma Neurofilament Light and Neurodegeneration in Patients With Alzheimer Disease}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2019.0765}, pmid = {31009028}, url = {https://doi.org/10.1001/jamaneurol.2019.0765} } @article{bergeron2018-30255971, author = {Bergeron, D. and Gorno-Tempini, M. L. and Rabinovici, G. D. and Santos-Santos, M. A. and Seeley, W. and Miller, B. L. and Pijnenburg, Y. and Keulen, M. A. and others}, title = {{Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia}}, journal = {Annals of neurology}, year = {2018}, doi = {10.1002/ana.25333}, pmid = {30255971}, url = {https://doi.org/10.1002/ana.25333} } @article{lanterorodriguez2020-32720099, author = {Lantero Rodriguez, J. and Karikari, T. K. and Suárez-Calvet, M. and Troakes, C. and King, A. and Emersic, A. and Aarsland, D. and Hye, A. and others}, title = {{Plasma p-tau181 accurately predicts Alzheimer's disease pathology at least 8 years prior to post-mortem and improves the clinical characterisation of cognitive decline}}, journal = {Acta neuropathologica}, year = {2020}, doi = {10.1007/s00401-020-02195-x}, pmid = {32720099}, url = {https://doi.org/10.1007/s00401-020-02195-x} } @article{karikari2021-33106600, author = {Karikari, T. K. and Benedet, A. L. and Ashton, N. J. and Lantero Rodriguez, J. and Snellman, A. and Suárez-Calvet, M. and Saha-Chaudhuri, P. and Lussier, F. and others}, title = {{Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer's Disease Neuroimaging Initiative}}, journal = {Molecular psychiatry}, year = {2021}, doi = {10.1038/s41380-020-00923-z}, pmid = {33106600}, url = {https://doi.org/10.1038/s41380-020-00923-z} } @article{xu2025-40067298, author = {Xu, X. and Kwon, J. and Yan, R. and Apio, C. and Song, S. and Heo, G. and Yang, Q. and Timsina, J. and others}, title = {{Sex Differences in Apolipoprotein E and Alzheimer Disease Pathology Across Ancestries}}, journal = {JAMA network open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.0562}, pmid = {40067298}, url = {https://doi.org/10.1001/jamanetworkopen.2025.0562} } @article{moscoso2025-40522652, author = {Moscoso, Alexis and Heeman, Fiona and Raghavan, Sheelakumari and Costoya‐Sánchez, Alejandro and van Essen, Martijn and Mainta, Ismini and Camacho, Valle and Rodríguez-Fonseca, Omar Darío and others}, title = {{Frequency and Clinical Outcomes Associated With Tau Positron Emission Tomography Positivity}}, journal = {JAMA}, year = {2025}, doi = {10.1001/jama.2025.7817}, pmid = {40522652}, url = {https://doi.org/10.1001/jama.2025.7817} } @article{mattsson2017-28346578, author = {Mattsson, N. and Andreasson, U. and Zetterberg, H. and Blennow, K. and {Alzheimer’s Disease Neuroimaging Initiative}}, title = {{Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer Disease}}, journal = {JAMA neurology}, year = {2017}, doi = {10.1001/jamaneurol.2016.6117}, pmid = {28346578}, url = {https://doi.org/10.1001/jamaneurol.2016.6117} } @article{benedet2021-34661615, author = {Benedet, A. L. and Milà-Alomà, M. and Vrillon, A. and Ashton, N. J. and Pascoal, T. A. and Lussier, F. and Karikari, T. K. and Hourregue, C. and others}, title = {{Differences Between Plasma and Cerebrospinal Fluid Glial Fibrillary Acidic Protein Levels Across the Alzheimer Disease Continuum}}, journal = {JAMA neurology}, year = {2021}, doi = {10.1001/jamaneurol.2021.3671}, pmid = {34661615}, url = {https://doi.org/10.1001/jamaneurol.2021.3671} } @article{moscoso2021-33427873, author = {Moscoso, A. and Grothe, M. J. and Ashton, N. J. and Karikari, T. K. and Lantero Rodríguez, J. and Snellman, A. and Suárez-Calvet, M. and Blennow, K. and others}, title = {{Longitudinal Associations of Blood Phosphorylated Tau181 and Neurofilament Light Chain With Neurodegeneration in Alzheimer Disease}}, journal = {JAMA neurology}, year = {2021}, doi = {10.1001/jamaneurol.2020.4986}, pmid = {33427873}, url = {https://doi.org/10.1001/jamaneurol.2020.4986} } @article{ryman2014-24928124, author = {Ryman, D. C. and Acosta-Baena, N. and Aisen, P. S. and Bird, T. and Danek, A. and Fox, N. C. and Goate, A. and Frommelt, P. and others}, title = {{Symptom onset in autosomal dominant Alzheimer disease: a systematic review and meta-analysis}}, journal = {Neurology}, year = {2014}, doi = {10.1212/wnl.0000000000000596}, pmid = {24928124}, url = {https://doi.org/10.1212/wnl.0000000000000596} } @article{mukadam2019-31000129, author = {Mukadam, N. and Sommerlad, A. and Huntley, J. and Livingston, G.}, title = {{Population attributable fractions for risk factors for dementia in low-income and middle-income countries: an analysis using cross-sectional survey data}}, journal = {The Lancet. Global health}, year = {2019}, doi = {10.1016/s2214-109x(19)30074-9}, pmid = {31000129}, url = {https://doi.org/10.1016/s2214-109x(19)30074-9} } @article{janelidze2020-32123385, author = {Janelidze, S. and Mattsson, N. and Palmqvist, S. and Smith, R. and Beach, T. G. and Serrano, G. E. and Chai, X. and Proctor, N. K. and others}, title = {{Plasma P-tau181 in Alzheimer's disease: relationship to other biomarkers, differential diagnosis, neuropathology and longitudinal progression to Alzheimer's dementia}}, journal = {Nature medicine}, year = {2020}, doi = {10.1038/s41591-020-0755-1}, pmid = {32123385}, url = {https://doi.org/10.1038/s41591-020-0755-1} } @article{woods2012-22336813, author = {Woods, B. and Aguirre, E. and Spector, A. E. and Orrell, M.}, title = {{Cognitive stimulation to improve cognitive functioning in people with dementia}}, journal = {The Cochrane database of systematic reviews}, year = {2012}, doi = {10.1002/14651858.cd005562.pub2}, pmid = {22336813}, url = {https://doi.org/10.1002/14651858.cd005562.pub2} } @article{woods2018-29493789, author = {Woods, B. and O'Philbin, L. and Farrell, E. M. and Spector, A. E. and Orrell, M.}, title = {{Reminiscence therapy for dementia}}, journal = {The Cochrane database of systematic reviews}, year = {2018}, doi = {10.1002/14651858.cd001120.pub3}, pmid = {29493789}, url = {https://doi.org/10.1002/14651858.cd001120.pub3} } @article{pottier2025-40280976, author = {Pottier, Cyril P. and Küçükali, Fahri and Baker, Matt C. and Batzler, Anthony and Jenkins, Gregory D. and van Blitterswijk, Marka and Vicente, Cristina T. and De Coster, Wouter and others}, title = {{Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing}}, journal = {Nature Communications}, year = {2025}, doi = {10.1038/s41467-025-59216-0}, pmid = {40280976}, url = {https://doi.org/10.1038/s41467-025-59216-0} } @article{preische2019-30664784, author = {Preische, O. and Schultz, S. A. and Apel, A. and Kuhle, J. and Kaeser, S. A. and Barro, C. and Gräber, S. and others}, title = {{Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer's disease}}, journal = {Nature medicine}, year = {2019}, doi = {10.1038/s41591-018-0304-3}, pmid = {30664784}, url = {https://doi.org/10.1038/s41591-018-0304-3} } @article{wagemann2024-38683602, author = {Wagemann, O. and Liu, H. and Wang, G. and Shi, X. and Bittner, T. and Scelsi, M. A. and Farlow, M. R. and Clifford, D. B. and others}, title = {{Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease: The DIAN-TU-001 Randomized Clinical Trial}}, journal = {JAMA neurology}, year = {2024}, doi = {10.1001/jamaneurol.2024.0991}, pmid = {38683602}, url = {https://doi.org/10.1001/jamaneurol.2024.0991} } @article{salloway2009-19923550, author = {Salloway, S. and Sperling, R. and Gilman, S. and Fox, N. C. and Blennow, K. and Raskind, M. and Sabbagh, M. and Honig, L. S. and others}, title = {{A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease}}, journal = {Neurology}, year = {2009}, doi = {10.1212/wnl.0b013e3181c67808}, pmid = {19923550}, url = {https://doi.org/10.1212/wnl.0b013e3181c67808} } @article{ashton2021-33585983, author = {Ashton, N. J. and Pascoal, T. A. and Karikari, T. K. and Benedet, A. L. and Lantero-Rodriguez, J. and Brinkmalm, G. and Snellman, A. and others}, title = {{Plasma p-tau231: a new biomarker for incipient Alzheimer's disease pathology}}, journal = {Acta neuropathologica}, year = {2021}, doi = {10.1007/s00401-021-02275-6}, pmid = {33585983}, url = {https://doi.org/10.1007/s00401-021-02275-6} } @article{moscoso2021-33257949, author = {Moscoso, A. and Grothe, M. J. and Ashton, N. J. and Karikari, T. K. and Rodriguez, J. L. and Snellman, A. and Suárez-Calvet, M. and Zetterberg, H. and others}, title = {{Time course of phosphorylated-tau181 in blood across the Alzheimer's disease spectrum}}, journal = {Brain : a journal of neurology}, year = {2021}, doi = {10.1093/brain/awaa399}, pmid = {33257949}, url = {https://doi.org/10.1093/brain/awaa399} } @article{woods2023-39804128, author = {Woods, B. and Rai, H. K. and Elliott, E. and Aguirre, E. and Orrell, M. and Spector, A.}, title = {{Cognitive stimulation to improve cognitive functioning in people with dementia}}, journal = {The Cochrane database of systematic reviews}, year = {2023}, doi = {10.1002/14651858.cd005562.pub3}, pmid = {39804128}, url = {https://doi.org/10.1002/14651858.cd005562.pub3} } @article{lawlor2018-30248105, author = {Lawlor, B. and Segurado, R. and Kennelly, S. and Olde Rikkert, M. G. M. and Howard, R. and Pasquier, F. and Börjesson-Hanson, A. and Tsolaki, M. and others}, title = {{Nilvadipine in mild to moderate Alzheimer disease: A randomised controlled trial}}, journal = {PLoS medicine}, year = {2018}, doi = {10.1371/journal.pmed.1002660}, pmid = {30248105}, url = {https://doi.org/10.1371/journal.pmed.1002660} } @article{mummery2026-41787076, author = {Mummery, C. J. and Mayorga, A. J. and Simmons, A. and Chow, T. W. and Burgess, B. and Nguyen, T. and Gao, J. and Budda, B. and Park, L. Q. and Gupta, R. and Li, C. and Shi, L. and others}, title = {{The TREM2 agonistic antibody AL002 in early Alzheimer's disease: a phase 2 randomized trial}}, journal = {Nature Medicine}, year = {2026}, doi = {10.1038/s41591-026-04273-1}, pmid = {41787076}, url = {https://doi.org/10.1038/s41591-026-04273-1} } @article{altomare2023-37155177, author = {Altomare, D. and Barkhof, F. and Caprioglio, C. and Collij, L. E. and Scheltens, P. and Lopes Alves, I. and Bouwman, F. and Berkhof, J. and others}, title = {{Clinical Effect of Early vs Late Amyloid Positron Emission Tomography in Memory Clinic Patients: The AMYPAD-DPMS Randomized Clinical Trial}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.0997}, pmid = {37155177}, url = {https://doi.org/10.1001/jamaneurol.2023.0997} } @article{andre2020-32202593, author = {André, C. and Rehel, S. and Kuhn, E. and Landeau, B. and Moulinet, I. and Touron, E. and Ourry, V. and Le Du, G. and others}, title = {{Association of Sleep-Disordered Breathing With Alzheimer Disease Biomarkers in Community-Dwelling Older Adults: A Secondary Analysis of a Randomized Clinical Trial}}, journal = {JAMA neurology}, year = {2020}, doi = {10.1001/jamaneurol.2020.0311}, pmid = {32202593}, url = {https://doi.org/10.1001/jamaneurol.2020.0311} } @article{kivimaki2020-32007134, author = {Kivimäki, M. and Batty, G. D. and Pentti, J. and Shipley, M. J. and Sipilä, P. N. and Nyberg, S. T. and Suominen, S. B. and Oksanen, T. and others}, title = {{Association between socioeconomic status and the development of mental and physical health conditions in adulthood: a multi-cohort study}}, journal = {The Lancet. Public health}, year = {2020}, doi = {10.1016/s2468-2667(19)30248-8}, pmid = {32007134}, url = {https://doi.org/10.1016/s2468-2667(19)30248-8} } @article{kivimaki2018-29169013, author = {Kivimäki, M. and Luukkonen, R. and Batty, G. D. and Ferrie, J. E. and Pentti, J. and Nyberg, S. T. and Shipley, M. J. and Alfredsson, L. and others}, title = {{Body mass index and risk of dementia: Analysis of individual-level data from 1.3 million individuals}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2018}, doi = {10.1016/j.jalz.2017.09.016}, pmid = {29169013}, url = {https://doi.org/10.1016/j.jalz.2017.09.016} } @article{sabia2017-28642251, author = {Sabia, S. and Dugravot, A. and Dartigues, J. F. and Abell, J. and Elbaz, A. and Kivimäki, M. and Singh-Manoux, A.}, title = {{Physical activity, cognitive decline, and risk of dementia: 28 year follow-up of Whitehall II cohort study}}, journal = {BMJ (Clinical research ed.)}, year = {2017}, doi = {10.1136/bmj.j2709}, pmid = {28642251}, url = {https://doi.org/10.1136/bmj.j2709} } @article{janelidze2018-30054439, author = {Janelidze, S. and Mattsson, N. and Stomrud, E. and Lindberg, O. and Palmqvist, S. and Zetterberg, H. and Blennow, K. and Hansson, O.}, title = {{CSF biomarkers of neuroinflammation and cerebrovascular dysfunction in early Alzheimer disease}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000006082}, pmid = {30054439}, url = {https://doi.org/10.1212/wnl.0000000000006082} } @article{mccarney2007-17608932, author = {McCarney, R. and Warner, J. and Iliffe, S. and van Haselen, R. and Griffin, M. and Fisher, P.}, title = {{The Hawthorne Effect: a randomised, controlled trial}}, journal = {BMC medical research methodology}, year = {2007}, doi = {10.1186/1471-2288-7-30}, pmid = {17608932}, url = {https://doi.org/10.1186/1471-2288-7-30} } @article{biessels2006-16361024, author = {Biessels, G. J. and Staekenborg, S. and Brunner, E. and Brayne, C. and Scheltens, P.}, title = {{Risk of dementia in diabetes mellitus: a systematic review}}, journal = {The Lancet. Neurology}, year = {2006}, doi = {10.1016/s1474-4422(05)70284-2}, pmid = {16361024}, url = {https://doi.org/10.1016/s1474-4422(05)70284-2} } @article{feldman2007-17509485, author = {Feldman, H. H. and Ferris, S. and Winblad, B. and Sfikas, N. and Mancione, L. and He, Y. and Tekin, S. and Burns, A. and others}, title = {{Effect of rivastigmine on delay to diagnosis of Alzheimer's disease from mild cognitive impairment: the InDDEx study}}, journal = {The Lancet. Neurology}, year = {2007}, doi = {10.1016/s1474-4422(07)70109-6}, pmid = {17509485}, url = {https://doi.org/10.1016/s1474-4422(07)70109-6} } @article{spector2003-12948999, author = {Spector, A. and Thorgrimsen, L. and Woods, B. and Royan, L. and Davies, S. and Butterworth, M. and Orrell, M.}, title = {{Efficacy of an evidence-based cognitive stimulation therapy programme for people with dementia: randomised controlled trial}}, journal = {The British journal of psychiatry : the journal of mental science}, year = {2003}, doi = {10.1192/bjp.183.3.248}, pmid = {12948999}, url = {https://doi.org/10.1192/bjp.183.3.248} } @article{li2026-41559019, author = {Li, Joanne M. and Gauen, Abigail and Zmora, Rachel and Stephen, John J. and Petito, Lucia C. and Scholtens, Denise and Peterson, Elizabeth and Kohli-Lynch, Ciaran Navin and others}, title = {{Midlife and late‐life population attributable fractions of risk factors for dementia in the United States: The Dementia Risk Prediction Project}}, journal = {Alzheimer s \& Dementia}, year = {2026}, doi = {10.1002/alz.71065}, pmid = {41559019}, url = {https://doi.org/10.1002/alz.71065} } @article{rapaport2024-39366393, author = {Rapaport, P. and Amador, S. and Adeleke, M. O. and Barber, J. A. and Banerjee, S. and Charlesworth, G. and others}, title = {{Clinical effectiveness of DREAMS START (Dementia Related Manual for Sleep; Strategies for Relatives) versus usual care for people with dementia and their carers: a single-masked, phase 3, parallel-arm, superiority randomised controlled trial}}, journal = {The Lancet Healthy Longevity}, year = {2024}, doi = {10.1016/j.lanhl.2024.08.004}, pmid = {39366393}, url = {https://doi.org/10.1016/j.lanhl.2024.08.004} } @article{benedict2020-31915189, author = {Benedict, C. and Blennow, K. and Zetterberg, H. and Cedernaes, J.}, title = {{Effects of acute sleep loss on diurnal plasma dynamics of CNS health biomarkers in young men}}, journal = {Neurology}, year = {2020}, doi = {10.1212/wnl.0000000000008866}, pmid = {31915189}, url = {https://doi.org/10.1212/wnl.0000000000008866} } @article{ashton2023-36877496, author = {Ashton, N. J. and Moseby-Knappe, M. and Benedet, A. L. and Grötschel, L. and Lantero-Rodriguez, J. and Karikari, T. K. and Hassager, C. and Wise, M. P. and others}, title = {{Alzheimer Disease Blood Biomarkers in Patients With Out-of-Hospital Cardiac Arrest}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.0050}, pmid = {36877496}, url = {https://doi.org/10.1001/jamaneurol.2023.0050} } @article{naj2014-25199842, author = {Naj, A. C. and Jun, G. and Reitz, C. and Kunkle, B. W. and Perry, W. and Park, Y. S. and Beecham, G. W. and Rajbhandary, R. A. and others}, title = {{Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study}}, journal = {JAMA neurology}, year = {2014}, doi = {10.1001/jamaneurol.2014.1491}, pmid = {25199842}, url = {https://doi.org/10.1001/jamaneurol.2014.1491} } @article{sabia2019-31391187, author = {Sabia, S. and Fayosse, A. and Dumurgier, J. and Schnitzler, A. and Empana, J. P. and Ebmeier, K. P. and Dugravot, A. and Kivimäki, M. and others}, title = {{Association of ideal cardiovascular health at age 50 with incidence of dementia: 25 year follow-up of Whitehall II cohort study}}, journal = {BMJ (Clinical research ed.)}, year = {2019}, doi = {10.1136/bmj.l4414}, pmid = {31391187}, url = {https://doi.org/10.1136/bmj.l4414} } @article{janelidze2023-36087307, author = {Janelidze, S. and Bali, D. and Ashton, N. J. and Barthélemy, N. R. and Vanbrabant, J. and Stoops, E. and Vanmechelen, E. and others}, title = {{Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2023}, doi = {10.1093/brain/awac333}, pmid = {36087307}, url = {https://doi.org/10.1093/brain/awac333} } @article{mckeith2007-17362834, author = {McKeith, I. and O'Brien, J. and Walker, Z. and Tatsch, K. and Booij, J. and Darcourt, J. and Padovani, A. and Giubbini, R. and others}, title = {{Sensitivity and specificity of dopamine transporter imaging with 123I-FP-CIT SPECT in dementia with Lewy bodies: a phase III, multicentre study}}, journal = {The Lancet. Neurology}, year = {2007}, doi = {10.1016/s1474-4422(07)70057-1}, pmid = {17362834}, url = {https://doi.org/10.1016/s1474-4422(07)70057-1} } @article{delpinocasado2019-31141556, author = {Del-Pino-Casado, R. and Rodríguez Cardosa, M. and López-Martínez, C. and Orgeta, V.}, title = {{The association between subjective caregiver burden and depressive symptoms in carers of older relatives: A systematic review and meta-analysis}}, journal = {PloS one}, year = {2019}, doi = {10.1371/journal.pone.0217648}, pmid = {31141556}, url = {https://doi.org/10.1371/journal.pone.0217648} } @article{lovden2020-32772803, author = {Lövdén, M. and Fratiglioni, L. and Glymour, M. M. and Lindenberger, U. and Tucker-Drob, E. M.}, title = {{Education and Cognitive Functioning Across the Life Span}}, journal = {Psychological science in the public interest : a journal of the American Psychological Society}, year = {2020}, doi = {10.1177/1529100620920576}, pmid = {32772803}, url = {https://doi.org/10.1177/1529100620920576} } @article{janelidze2021-34542571, author = {Janelidze, S. and Teunissen, C. E. and Zetterberg, H. and Allué, J. A. and Sarasa, L. and Eichenlaub, U. and Bittner, T. and Ovod, V. and others}, title = {{Head-to-Head Comparison of 8 Plasma Amyloid-β 42/40 Assays in Alzheimer Disease}}, journal = {JAMA neurology}, year = {2021}, doi = {10.1001/jamaneurol.2021.3180}, pmid = {34542571}, url = {https://doi.org/10.1001/jamaneurol.2021.3180} } @article{wischik2015-25550228, author = {Wischik, C. M. and Staff, R. T. and Wischik, D. J. and Bentham, P. and Murray, A. D. and Storey, J. M. and Kook, K. A. and Harrington, C. R.}, title = {{Tau aggregation inhibitor therapy: an exploratory phase 2 study in mild or moderate Alzheimer's disease}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2015}, doi = {10.3233/jad-142874}, pmid = {25550228}, url = {https://doi.org/10.3233/jad-142874} } @article{scott2018-29272357, author = {Scott, G. and Zetterberg, H. and Jolly, A. and Cole, J. H. and De Simoni, S. and Jenkins, P. O. and Feeney, C. and Owen, D. R. and others}, title = {{Minocycline reduces chronic microglial activation after brain trauma but increases neurodegeneration}}, journal = {Brain : a journal of neurology}, year = {2018}, doi = {10.1093/brain/awx339}, pmid = {29272357}, url = {https://doi.org/10.1093/brain/awx339} } @article{cummings2026-41865758, author = {Cummings, Jeffrey L and Atri, Alireza and Sano, Mary and Zetterberg, Henrik and Scheltens, Philip and Knop, Filip K and Johannsen, Peter and Wichmann, Christian Ahmad and others}, title = {{Efficacy and safety of oral semaglutide 14 mg (flexible dose) in early-stage symptomatic Alzheimer's disease (evoke and evoke+): two phase 3, randomised, placebo-controlled trials}}, journal = {The Lancet}, year = {2026}, doi = {10.1016/s0140-6736(26)00459-9}, pmid = {41865758}, url = {https://doi.org/10.1016/s0140-6736(26)00459-9} } @article{jack2008-18302232, author = {Jack, Clifford R. and Bernstein, Matt A. and Fox, Nick C. and Thompson, Paul M. and Alexander, Gene E. and Harvey, Danielle Jenine and Borowski, Bret and Britson, Paula J. and others}, title = {{The Alzheimer's disease neuroimaging initiative (ADNI): MRI methods}}, journal = {Journal of Magnetic Resonance Imaging}, year = {2008}, doi = {10.1002/jmri.21049}, pmid = {18302232}, url = {https://doi.org/10.1002/jmri.21049} } @article{heneka2025-40050444, author = {Heneka, M. T. and Gauthier, S. and Chandekar, S. A. and Hviid Hahn-Pedersen, J. and Bentsen, M. A. and Zetterberg, H.}, title = {{Neuroinflammatory fluid biomarkers in patients with Alzheimer's disease: a systematic literature review}}, journal = {Molecular psychiatry}, year = {2025}, doi = {10.1038/s41380-025-02939-9}, pmid = {40050444}, url = {https://doi.org/10.1038/s41380-025-02939-9} } @article{sommerlad2019-31374073, author = {Sommerlad, A. and Sabia, S. and Singh-Manoux, A. and Lewis, G. and Livingston, G.}, title = {{Association of social contact with dementia and cognition: 28-year follow-up of the Whitehall II cohort study}}, journal = {PLoS Medicine}, year = {2019}, doi = {10.1371/journal.pmed.1002862}, pmid = {31374073}, url = {https://doi.org/10.1371/journal.pmed.1002862} } @article{mummery2023-37095250, author = {Mummery, C. J. and Börjesson-Hanson, A. and Blackburn, D. J. and Vijverberg, E. G. B. and De Deyn, P. P. and Ducharme, S. and Jonsson, M. and Schneider, A. and Rinne, J. O. and Ludolph, A. C. and Bodenschatz, R. and Kordasiewicz, H. and others}, title = {{Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer's disease: a phase 1b, randomized, placebo-controlled trial}}, journal = {Nature Medicine}, year = {2023}, doi = {10.1038/s41591-023-02326-3}, pmid = {37095250}, url = {https://doi.org/10.1038/s41591-023-02326-3} } @article{wang2025-40156286, author = {Wang, J. and Huang, S. and Lan, G. and Lai, Y. J. and Wang, Q. H. and Chen, Y. and Xiao, Z. S. and Chen, X. and Bu, X. L. and Liu, Y. H. and Zeng, F. and Zhang, L. and others}, title = {{Diagnostic accuracy of plasma p-tau217/Aβ42 for Alzheimer's disease in clinical and community cohorts}}, journal = {Alzheimer's \& Dementia}, year = {2025}, doi = {10.1002/alz.70038}, pmid = {40156286}, url = {https://doi.org/10.1002/alz.70038} } @article{palmqvist2019-31233127, author = {Palmqvist, S. and Janelidze, S. and Stomrud, E. and Zetterberg, H. and Karl, J. and Zink, K. and Bittner, T. and Mattsson, N. and others}, title = {{Performance of Fully Automated Plasma Assays as Screening Tests for Alzheimer Disease-Related β-Amyloid Status}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2019.1632}, pmid = {31233127}, url = {https://doi.org/10.1001/jamaneurol.2019.1632} } @article{therriault2023-36508198, author = {Therriault, J. and Vermeiren, M. and Servaes, S. and Tissot, C. and Ashton, N. J. and Benedet, A. L. and Karikari, T. K. and Lantero-Rodriguez, J. and others}, title = {{Association of Phosphorylated Tau Biomarkers With Amyloid Positron Emission Tomography vs Tau Positron Emission Tomography}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2022.4485}, pmid = {36508198}, url = {https://doi.org/10.1001/jamaneurol.2022.4485} } @article{lane2019-31444142, author = {Lane, C. A. and Barnes, J. and Nicholas, J. M. and Sudre, C. H. and Cash, D. M. and Parker, T. D. and Malone, I. B. and Lu, K. and others}, title = {{Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epidemiological study}}, journal = {The Lancet. Neurology}, year = {2019}, doi = {10.1016/s1474-4422(19)30228-5}, pmid = {31444142}, url = {https://doi.org/10.1016/s1474-4422(19)30228-5} } @article{hohman2018-29801024, author = {Hohman, T. J. and Dumitrescu, L. and Barnes, L. L. and Thambisetty, M. and Beecham, G. and Kunkle, B. and Gifford, K. A. and Bush, W. S. and others}, title = {{Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau}}, journal = {JAMA neurology}, year = {2018}, doi = {10.1001/jamaneurol.2018.0821}, pmid = {29801024}, url = {https://doi.org/10.1001/jamaneurol.2018.0821} } @article{kern2018-29653987, author = {Kern, S. and Zetterberg, H. and Kern, J. and Zettergren, A. and Waern, M. and Höglund, K. and Andreasson, U. and Wetterberg, H. and others}, title = {{Prevalence of preclinical Alzheimer disease: Comparison of current classification systems}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000005476}, pmid = {29653987}, url = {https://doi.org/10.1212/wnl.0000000000005476} } @article{sommerlad2018-29183957, author = {Sommerlad, A. and Ruegger, J. and Singh-Manoux, A. and Lewis, G. and Livingston, G.}, title = {{Marriage and risk of dementia: systematic review and meta-analysis of observational studies}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2018}, doi = {10.1136/jnnp-2017-316274}, pmid = {29183957}, url = {https://doi.org/10.1136/jnnp-2017-316274} } @article{nalls2013-23588557, author = {Nalls, M. A. and Duran, R. and Lopez, G. and Kurzawa-Akanbi, M. and McKeith, I. G. and Chinnery, P. F. and Morris, C. M. and Theuns, J. and others}, title = {{A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies}}, journal = {JAMA neurology}, year = {2013}, doi = {10.1001/jamaneurol.2013.1925}, pmid = {23588557}, url = {https://doi.org/10.1001/jamaneurol.2013.1925} } @article{curtis2015-25622185, author = {Curtis, C. and Gamez, J. E. and Singh, U. and Sadowsky, C. H. and Villena, T. and Sabbagh, M. N. and Beach, T. G. and Duara, R. and others}, title = {{Phase 3 trial of flutemetamol labeled with radioactive fluorine 18 imaging and neuritic plaque density}}, journal = {JAMA neurology}, year = {2015}, doi = {10.1001/jamaneurol.2014.4144}, pmid = {25622185}, url = {https://doi.org/10.1001/jamaneurol.2014.4144} } @article{morenasrodriguez2022-35305339, author = {Morenas-Rodríguez, E. and Li, Y. and Nuscher, B. and Franzmeier, N. and Xiong, C. and Suárez-Calvet, M. and Fagan, A. M. and Schultz, S. and others}, title = {{Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study}}, journal = {The Lancet. Neurology}, year = {2022}, doi = {10.1016/s1474-4422(22)00027-8}, pmid = {35305339}, url = {https://doi.org/10.1016/s1474-4422(22)00027-8} } @article{bunn2012-23118618, author = {Bunn, F. and Goodman, C. and Sworn, K. and Rait, G. and Brayne, C. and Robinson, L. and McNeilly, E. and Iliffe, S.}, title = {{Psychosocial factors that shape patient and carer experiences of dementia diagnosis and treatment: a systematic review of qualitative studies}}, journal = {PLoS medicine}, year = {2012}, doi = {10.1371/journal.pmed.1001331}, pmid = {23118618}, url = {https://doi.org/10.1371/journal.pmed.1001331} } @article{orgeta2020-32101639, author = {Orgeta, V. and McDonald, K. R. and Poliakoff, E. and Hindle, J. V. and Clare, L. and Leroi, I.}, title = {{Cognitive training interventions for dementia and mild cognitive impairment in Parkinson's disease}}, journal = {The Cochrane database of systematic reviews}, year = {2020}, doi = {10.1002/14651858.cd011961.pub2}, pmid = {32101639}, url = {https://doi.org/10.1002/14651858.cd011961.pub2} } @article{sabia2021-33879784, author = {Sabia, S. and Fayosse, A. and Dumurgier, J. and van Hees, V. T. and Paquet, C. and Sommerlad, A. and Kivimäki, M. and Dugravot, A. and others}, title = {{Association of sleep duration in middle and old age with incidence of dementia}}, journal = {Nature communications}, year = {2021}, doi = {10.1038/s41467-021-22354-2}, pmid = {33879784}, url = {https://doi.org/10.1038/s41467-021-22354-2} } @article{ashton2021-34099648, author = {Ashton, N. J. and Janelidze, S. and Al Khleifat, A. and Leuzy, A. and van der Ende, E. L. and Karikari, T. K. and Benedet, A. L. and Pascoal, T. A. and others}, title = {{A multicentre validation study of the diagnostic value of plasma neurofilament light}}, journal = {Nature communications}, year = {2021}, doi = {10.1038/s41467-021-23620-z}, pmid = {34099648}, url = {https://doi.org/10.1038/s41467-021-23620-z} } @article{palmqvist2021-34031605, author = {Palmqvist, S. and Tideman, P. and Cullen, N. and Zetterberg, H. and Blennow, K. and {Alzheimer’s Disease Neuroimaging Initiative} and Dage, J. L. and Stomrud, E. and others}, title = {{Prediction of future Alzheimer's disease dementia using plasma phospho-tau combined with other accessible measures}}, journal = {Nature medicine}, year = {2021}, doi = {10.1038/s41591-021-01348-z}, pmid = {34031605}, url = {https://doi.org/10.1038/s41591-021-01348-z} } @article{vanloenhoud2019-31266904, author = {van Loenhoud, A. C. and van der Flier, W. M. and Wink, A. M. and Dicks, E. and Groot, C. and Twisk, J. and Barkhof, F. and Scheltens, P. and others}, title = {{Cognitive reserve and clinical progression in Alzheimer disease: A paradoxical relationship}}, journal = {Neurology}, year = {2019}, doi = {10.1212/wnl.0000000000007821}, pmid = {31266904}, url = {https://doi.org/10.1212/wnl.0000000000007821} } @article{singhmanoux2014-24991031, author = {Singh-Manoux, A. and Dugravot, A. and Brunner, E. and Kumari, M. and Shipley, M. and Elbaz, A. and Kivimaki, M.}, title = {{Interleukin-6 and C-reactive protein as predictors of cognitive decline in late midlife}}, journal = {Neurology}, year = {2014}, doi = {10.1212/wnl.0000000000000665}, pmid = {24991031}, url = {https://doi.org/10.1212/wnl.0000000000000665} } @article{davis2015-26513331, author = {Davis, D. H. and Creavin, S. T. and Yip, J. L. and Noel-Storr, A. H. and Brayne, C. and Cullum, S.}, title = {{Montreal Cognitive Assessment for the diagnosis of Alzheimer's disease and other dementias}}, journal = {The Cochrane database of systematic reviews}, year = {2015}, doi = {10.1002/14651858.cd010775.pub2}, pmid = {26513331}, url = {https://doi.org/10.1002/14651858.cd010775.pub2} } @article{orrell2017-28350796, author = {Orrell, M. and Yates, L. and Leung, P. and Kang, S. and Hoare, Z. and Whitaker, C. and Burns, A. and others}, title = {{The impact of individual Cognitive Stimulation Therapy (iCST) on cognition, quality of life, caregiver health, and family relationships in dementia: A randomised controlled trial}}, journal = {PLoS medicine}, year = {2017}, doi = {10.1371/journal.pmed.1002269}, pmid = {28350796}, url = {https://doi.org/10.1371/journal.pmed.1002269} } @article{sevigny2024-38745011, author = {Sevigny, J. and Uspenskaya, O. and Heckman, L. D. and Wong, L. C. and Hatch, D. A. and Tewari, A. and Vandenberghe, R. and Irwin, D. J. and others}, title = {{Progranulin AAV gene therapy for frontotemporal dementia: translational studies and phase 1/2 trial interim results}}, journal = {Nature medicine}, year = {2024}, doi = {10.1038/s41591-024-02973-0}, pmid = {38745011}, url = {https://doi.org/10.1038/s41591-024-02973-0} } @article{broce2018-29315334, author = {Broce, I. and Karch, C. M. and Wen, N. and Fan, C. C. and Wang, Y. and Tan, C. H. and Kouri, N. and Ross, O. A. and others}, title = {{Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies}}, journal = {PLoS medicine}, year = {2018}, doi = {10.1371/journal.pmed.1002487}, pmid = {29315334}, url = {https://doi.org/10.1371/journal.pmed.1002487} } @article{petersen2026-41714746, author = {Petersen, Kellen K and Milà-Alomà, Marta and Li, Yan and Du, Lianlian and Xiong, Chengjie and Tosun, Duygu and Saef, Benjamin and Saad, Ziad S and others}, title = {{Predicting onset of symptomatic Alzheimer's disease with plasma p-tau217 clocks}}, journal = {Nature medicine}, year = {2026}, doi = {10.1038/s41591-026-04206-y}, pmid = {41714746}, url = {https://doi.org/10.1038/s41591-026-04206-y} } @article{yakoub2025-40008832, author = {Yakoub, Y. and Gonzalez-Ortiz, F. and Ashton, N. J. and Déry, C. and Strikwerda-Brown, C. and St-Onge, F. and Ourry, V. and Schöll, M. and Geddes, M. R. and Ducharme, S. and Montembeault, M. and Rosa-Neto, P. and others}, title = {{Plasma p-tau217 identifies cognitively normal older adults who will develop cognitive impairment in a 10-year window}}, journal = {Alzheimer's \& Dementia}, year = {2025}, doi = {10.1002/alz.14537}, pmid = {40008832}, url = {https://doi.org/10.1002/alz.14537} } @article{sanchez2025-40063856, author = {Sanchez, E. and Coughlan, G. T. and Wilkinson, T. and Ramirez, J. and Mirza, S. S. and Baril, A. A. and Dilliott, A. A. and Frank, A. and others}, title = {{Association of Plasma Biomarkers With Longitudinal Atrophy and Microvascular Burden on MRI Across Neurodegenerative and Cerebrovascular Diseases}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000213438}, pmid = {40063856}, url = {https://doi.org/10.1212/wnl.0000000000213438} } @article{gonzalezortiz2025-40373247, author = {Gonzalez-Ortiz, F. and Kirsebom, B. E. and Yakoub, Y. and Gundersen, J. K. and Pålhaugen, L. and Waterloo, K. and Selnes, P. and Jarholm, J. A. and others}, title = {{Associations Between Changes in Levels of Phosphorylated Tau and Severity of Cognitive Impairment in Early Alzheimer Disease}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000213676}, pmid = {40373247}, url = {https://doi.org/10.1212/wnl.0000000000213676} } @article{hithersay2019-30452522, author = {Hithersay, R. and Startin, C. M. and Hamburg, S. and Mok, K. Y. and Hardy, J. and Fisher, E. M. C. and Tybulewicz, V. L. J. and Nizetic, D. and others}, title = {{Association of Dementia With Mortality Among Adults With Down Syndrome Older Than 35 Years}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2018.3616}, pmid = {30452522}, url = {https://doi.org/10.1001/jamaneurol.2018.3616} } @article{nagga2018-29196581, author = {Nägga, K. and Gustavsson, A. M. and Stomrud, E. and Lindqvist, D. and van Westen, D. and Blennow, K. and Zetterberg, H. and Melander, O. and others}, title = {{Increased midlife triglycerides predict brain β-amyloid and tau pathology 20 years later}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000004749}, pmid = {29196581}, url = {https://doi.org/10.1212/wnl.0000000000004749} } @article{buergel2022-36138150, author = {Buergel, T. and Steinfeldt, J. and Ruyoga, G. and Pietzner, M. and Bizzarri, D. and Vojinovic, D. and Upmeier Zu Belzen, J. and Loock, L. and others}, title = {{Metabolomic profiles predict individual multidisease outcomes}}, journal = {Nature medicine}, year = {2022}, doi = {10.1038/s41591-022-01980-3}, pmid = {36138150}, url = {https://doi.org/10.1038/s41591-022-01980-3} } @article{dugravot2020-31837974, author = {Dugravot, A. and Fayosse, A. and Dumurgier, J. and Bouillon, K. and Rayana, T. B. and Schnitzler, A. and Kivimaki, M. and Sabia, S. and others}, title = {{Social inequalities in multimorbidity, frailty, disability, and transitions to mortality: a 24-year follow-up of the Whitehall II cohort study}}, journal = {The Lancet. Public health}, year = {2020}, doi = {10.1016/s2468-2667(19)30226-9}, pmid = {31837974}, url = {https://doi.org/10.1016/s2468-2667(19)30226-9} } @article{deckers2019-31424404, author = {Deckers, K. and Cadar, D. and van Boxtel, M. P. J. and Verhey, F. R. J. and Steptoe, A. and Köhler, S.}, title = {{Modifiable Risk Factors Explain Socioeconomic Inequalities in Dementia Risk: Evidence from a Population-Based Prospective Cohort Study}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2019}, doi = {10.3233/jad-190541}, pmid = {31424404}, url = {https://doi.org/10.3233/jad-190541} } @article{williamsgray2009-19812213, author = {Williams-Gray, C. H. and Evans, JR. and Goris, A. and Foltynie, T. and Ban, M. and Robbins, T. W. and Brayne, C. and Kolachana, B. S. and others}, title = {{The distinct cognitive syndromes of Parkinson's disease: 5 year follow-up of the CamPaIGN cohort}}, journal = {Brain : a journal of neurology}, year = {2009}, doi = {10.1093/brain/awp245}, pmid = {19812213}, url = {https://doi.org/10.1093/brain/awp245} } @article{singhmanoux2017-28514478, author = {Singh-Manoux, A. and Dugravot, A. and Fournier, A. and Abell, J. and Ebmeier, K. and Kivimäki, M. and Sabia, S.}, title = {{Trajectories of Depressive Symptoms Before Diagnosis of Dementia: A 28-Year Follow-up Study}}, journal = {JAMA psychiatry}, year = {2017}, doi = {10.1001/jamapsychiatry.2017.0660}, pmid = {28514478}, url = {https://doi.org/10.1001/jamapsychiatry.2017.0660} } @article{halliday2011-21720849, author = {Halliday, G. M. and Holton, J. L. and Revesz, T. and Dickson, D. W.}, title = {{Neuropathology underlying clinical variability in patients with synucleinopathies}}, journal = {Acta neuropathologica}, year = {2011}, doi = {10.1007/s00401-011-0852-9}, pmid = {21720849}, url = {https://doi.org/10.1007/s00401-011-0852-9} } @article{dube2019-31591557, author = {Dube, U. and Del-Aguila, J. L. and Li, Z. and Budde, J. P. and Jiang, S. and Hsu, S. and Ibanez, L. and Fernandez, M. V. and others}, title = {{An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations}}, journal = {Nature neuroscience}, year = {2019}, doi = {10.1038/s41593-019-0501-5}, pmid = {31591557}, url = {https://doi.org/10.1038/s41593-019-0501-5} } @article{davis2017-28114436, author = {Davis, D. H. and Muniz-Terrera, G. and Keage, H. A. and Stephan, B. C. and Fleming, J. and Ince, P. G. and Matthews, F. E. and Cunningham, C. and others}, title = {{Association of Delirium With Cognitive Decline in Late Life: A Neuropathologic Study of 3 Population-Based Cohort Studies}}, journal = {JAMA psychiatry}, year = {2017}, doi = {10.1001/jamapsychiatry.2016.3423}, pmid = {28114436}, url = {https://doi.org/10.1001/jamapsychiatry.2016.3423} } @article{hopwood2018-29895512, author = {Hopwood, J. and Walker, N. and McDonagh, L. and Rait, G. and Walters, K. and Iliffe, S. and Ross, J. and Davies, N.}, title = {{Internet-Based Interventions Aimed at Supporting Family Caregivers of People With Dementia: Systematic Review}}, journal = {Journal of medical Internet research}, year = {2018}, doi = {10.2196/jmir.9548}, pmid = {29895512}, url = {https://doi.org/10.2196/jmir.9548} } @article{leung2021-33905138, author = {Leung, D. K. Y. and Chan, W. C. and Spector, A. and Wong, G. H. Y.}, title = {{Prevalence of depression, anxiety, and apathy symptoms across dementia stages: A systematic review and meta-analysis}}, journal = {International journal of geriatric psychiatry}, year = {2021}, doi = {10.1002/gps.5556}, pmid = {33905138}, url = {https://doi.org/10.1002/gps.5556} } @article{sipila2021-34166620, author = {Sipilä, P. N. and Heikkilä, N. and Lindbohm, J. V. and Hakulinen, C. and Vahtera, J. and Elovainio, M. and Suominen, S. and Väänänen, A. and others}, title = {{Hospital-treated infectious diseases and the risk of dementia: a large, multicohort, observational study with a replication cohort}}, journal = {The Lancet. Infectious diseases}, year = {2021}, doi = {10.1016/s1473-3099(21)00144-4}, pmid = {34166620}, url = {https://doi.org/10.1016/s1473-3099(21)00144-4} } @article{sommerlad2018-29703698, author = {Sommerlad, A. and Perera, G. and Singh-Manoux, A. and Lewis, G. and Stewart, R. and Livingston, G.}, title = {{Accuracy of general hospital dementia diagnoses in England: Sensitivity, specificity, and predictors of diagnostic accuracy 2008-2016}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2018}, doi = {10.1016/j.jalz.2018.02.012}, pmid = {29703698}, url = {https://doi.org/10.1016/j.jalz.2018.02.012} } @article{bridel2019-31206160, author = {Bridel, C. and van Wieringen, W. N. and Zetterberg, H. and Tijms, B. M. and Teunissen, C. E. and {the NFL Group} and Alvarez-Cermeño, J. C. and Andreasson, U. and others}, title = {{Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2019.1534}, pmid = {31206160}, url = {https://doi.org/10.1001/jamaneurol.2019.1534} } @article{jabbari2020-31860007, author = {Jabbari, E. and Holland, N. and Chelban, V. and Jones, P. S. and Lamb, R. and Rawlinson, C. and Guo, T. and Costantini, A. A. and others}, title = {{Diagnosis Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Syndrome}}, journal = {JAMA neurology}, year = {2020}, doi = {10.1001/jamaneurol.2019.4347}, pmid = {31860007}, url = {https://doi.org/10.1001/jamaneurol.2019.4347} } @article{farina2017-28167069, author = {Farina, N. and Page, T. E. and Daley, S. and Brown, A. and Bowling, A. and Basset, T. and Livingston, G. and Knapp, M. and others}, title = {{Factors associated with the quality of life of family carers of people with dementia: A systematic review}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2017}, doi = {10.1016/j.jalz.2016.12.010}, pmid = {28167069}, url = {https://doi.org/10.1016/j.jalz.2016.12.010} } @article{zaninotto2018-29691286, author = {Zaninotto, P. and Batty, G. D. and Allerhand, M. and Deary, I. J.}, title = {{Cognitive function trajectories and their determinants in older people: 8 years of follow-up in the English Longitudinal Study of Ageing}}, journal = {Journal of epidemiology and community health}, year = {2018}, doi = {10.1136/jech-2017-210116}, pmid = {29691286}, url = {https://doi.org/10.1136/jech-2017-210116} } @article{selikhova2009-19759203, author = {Selikhova, M. and Williams, D. R. and Kempster, P. A. and Holton, J. L. and Revesz, T. and Lees, A. J.}, title = {{A clinico-pathological study of subtypes in Parkinson's disease}}, journal = {Brain : a journal of neurology}, year = {2009}, doi = {10.1093/brain/awp234}, pmid = {19759203}, url = {https://doi.org/10.1093/brain/awp234} } @article{benitez2014-24439484, author = {Benitez, B. A. and Jin, S. C. and Guerreiro, R. and Graham, R. and Lord, J. and Harold, D. and Sims, R. and Lambert, J. C. and others}, title = {{Missense variant in TREML2 protects against Alzheimer's disease}}, journal = {Neurobiology of aging}, year = {2014}, doi = {10.1016/j.neurobiolaging.2013.12.010}, pmid = {24439484}, url = {https://doi.org/10.1016/j.neurobiolaging.2013.12.010} } @article{costoyasanchez2023-37578787, author = {Costoya-Sánchez, A. and Moscoso, A. and Silva-Rodríguez, J. and Pontecorvo, M. J. and Devous, M. D. and Aguiar, P. and Schöll, M. and Grothe, M. J. and others}, title = {{Increased Medial Temporal Tau Positron Emission Tomography Uptake in the Absence of Amyloid-β Positivity}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.2560}, pmid = {37578787}, url = {https://doi.org/10.1001/jamaneurol.2023.2560} } @article{kivimaki2023-37310738, author = {Kivimäki, M. and Livingston, G. and Singh-Manoux, A. and Mars, N. and Lindbohm, J. V. and Pentti, J. and Nyberg, S. T. and Pirinen, M. and others}, title = {{Estimating Dementia Risk Using Multifactorial Prediction Models}}, journal = {JAMA network open}, year = {2023}, doi = {10.1001/jamanetworkopen.2023.18132}, pmid = {37310738}, url = {https://doi.org/10.1001/jamanetworkopen.2023.18132} } @article{dicken2025-40760353, author = {Dicken, Samuel James and Jassil, Friedrich C. and Brown, Adrian Carl and Kalis, Monika and Stanley, Chloe and Ranson, Chaniqua and Ruwona, Tapiwa and Qamar, Sulmaaz and others}, title = {{Ultraprocessed or minimally processed diets following healthy dietary guidelines on weight and cardiometabolic health: a randomized, crossover trial}}, journal = {Nature Medicine}, year = {2025}, doi = {10.1038/s41591-025-03842-0}, pmid = {40760353}, url = {https://doi.org/10.1038/s41591-025-03842-0} } @article{isaaq2025-39978389, author = {Isaaq, A. and Cooper, C. and Vickerstaff, V. and Barber, J. A. and Walters, K. and Lang, I. A. and Rapaport, P. and Orgeta, V. and Rockwood, K. and Butler, L. T. and Lord, K. and Livingston, G. and others}, title = {{Cost-utility of a new psychosocial goal-setting and manualised support intervention for independence in dementia (NIDUS-Family) versus goal setting and routine care: an economic evaluation embedded within a randomised controlled trial}}, journal = {The Lancet Healthy Longevity}, year = {2025}, doi = {10.1016/j.lanhl.2024.100676}, pmid = {39978389}, url = {https://doi.org/10.1016/j.lanhl.2024.100676} } @article{roemercassiano2025-39841807, author = {Roemer-Cassiano, S. N. and Wagner, F. and Evangelista, L. and Rauchmann, B. S. and Dehsarvi, A. and Steward, A. and Dewenter, A. and Biel, D. and Zhu, Z. and Pescoller, J. and Gross, M. and Perneczky, R. and others}, title = {{Amyloid-associated hyperconnectivity drives tau spread across connected brain regions in Alzheimer's disease}}, journal = {Science Translational Medicine}, year = {2025}, doi = {10.1126/scitranslmed.adp2564}, pmid = {39841807}, url = {https://doi.org/10.1126/scitranslmed.adp2564} } @article{cicognola2021-33773595, author = {Cicognola, C. and Janelidze, S. and Hertze, J. and Zetterberg, H. and Blennow, K. and Mattsson-Carlgren, N. and Hansson, O.}, title = {{Plasma glial fibrillary acidic protein detects Alzheimer pathology and predicts future conversion to Alzheimer dementia in patients with mild cognitive impairment}}, journal = {Alzheimer's research \& therapy}, year = {2021}, doi = {10.1186/s13195-021-00804-9}, pmid = {33773595}, url = {https://doi.org/10.1186/s13195-021-00804-9} } @article{olsson2019-30508027, author = {Olsson, B. and Portelius, E. and Cullen, N. C. and Å, Sandelius and Zetterberg, H. and Andreasson, U. and Höglund, K. and Irwin, D. J. and others}, title = {{Association of Cerebrospinal Fluid Neurofilament Light Protein Levels With Cognition in Patients With Dementia, Motor Neuron Disease, and Movement Disorders}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2018.3746}, pmid = {30508027}, url = {https://doi.org/10.1001/jamaneurol.2018.3746} } @article{collij2020-32675080, author = {Collij, L. E. and Heeman, F. and Salvadó, G. and Ingala, S. and Altomare, D. and de Wilde, A. and Konijnenberg, E. and van Buchem, M. and others}, title = {{Multitracer model for staging cortical amyloid deposition using PET imaging}}, journal = {Neurology}, year = {2020}, doi = {10.1212/wnl.0000000000010256}, pmid = {32675080}, url = {https://doi.org/10.1212/wnl.0000000000010256} } @article{dittrich2023-37225431, author = {Dittrich, A. and Ashton, N. J. and Zetterberg, H. and Blennow, K. and Zettergren, A. and Simrén, J. and Skillbäck, T. and Shams, S. and others}, title = {{Association of Chronic Kidney Disease With Plasma NfL and Other Biomarkers of Neurodegeneration: The H70 Birth Cohort Study in Gothenburg}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000207419}, pmid = {37225431}, url = {https://doi.org/10.1212/wnl.0000000000207419} } @article{pichetbinette2025-40388185, author = {Pichet Binette, A. and Smith, R. and Salvadó, G. and Tideman, P. and Glans, I. and van Westen, D. and Groot, C. and Ossenkoppele, R. and others}, title = {{Evaluation of the Revised Criteria for Biological and Clinical Staging of Alzheimer Disease}}, journal = {JAMA neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.1100}, pmid = {40388185}, url = {https://doi.org/10.1001/jamaneurol.2025.1100} } @article{liu2018-29429971, author = {Liu, E. and Wang, D. and Sperling, R. and Salloway, S. and Fox, N. C. and Blennow, K. and Scheltens, P. and Schmidt, M. E. and others}, title = {{Biomarker pattern of ARIA-E participants in phase 3 randomized clinical trials with bapineuzumab}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000005060}, pmid = {29429971}, url = {https://doi.org/10.1212/wnl.0000000000005060} } @article{thal1996-8960716, author = {Thal, L. J. and Schwartz, G. and Sano, M. and Weiner, M. and Knopman, D. and Harrell, L. and Bodenheimer, S. and Rossor, M. and others}, title = {{A multicenter double-blind study of controlled-release physostigmine for the treatment of symptoms secondary to Alzheimer's disease. Physostigmine Study Group}}, journal = {Neurology}, year = {1996}, doi = {10.1212/wnl.47.6.1389}, pmid = {8960716}, url = {https://doi.org/10.1212/wnl.47.6.1389} } @article{pal2018-30182156, author = {Pal, K. and Mukadam, N. and Petersen, I. and Cooper, C.}, title = {{Mild cognitive impairment and progression to dementia in people with diabetes, prediabetes and metabolic syndrome: a systematic review and meta-analysis}}, journal = {Social psychiatry and psychiatric epidemiology}, year = {2018}, doi = {10.1007/s00127-018-1581-3}, pmid = {30182156}, url = {https://doi.org/10.1007/s00127-018-1581-3} } @article{lang2017-28159845, author = {Lang, L. and Clifford, A. and Wei, L. and Zhang, D. and Leung, D. and Augustine, G. and Danat, I. M. and Zhou, W. and others}, title = {{Prevalence and determinants of undetected dementia in the community: a systematic literature review and a meta-analysis}}, journal = {BMJ open}, year = {2017}, doi = {10.1136/bmjopen-2016-011146}, pmid = {28159845}, url = {https://doi.org/10.1136/bmjopen-2016-011146} } @article{hansson2023-37202517, author = {Hansson, O. and Blennow, K. and Zetterberg, H. and Dage, J.}, title = {{Blood biomarkers for Alzheimer's disease in clinical practice and trials}}, journal = {Nature aging}, year = {2023}, doi = {10.1038/s43587-023-00403-3}, pmid = {37202517}, url = {https://doi.org/10.1038/s43587-023-00403-3} } @article{schrag2017-27866858, author = {Schrag, A. and Siddiqui, U. F. and Anastasiou, Z. and Weintraub, D. and Schott, J. M.}, title = {{Clinical variables and biomarkers in prediction of cognitive impairment in patients with newly diagnosed Parkinson's disease: a cohort study}}, journal = {The Lancet. Neurology}, year = {2017}, doi = {10.1016/s1474-4422(16)30328-3}, pmid = {27866858}, url = {https://doi.org/10.1016/s1474-4422(16)30328-3} } @article{gilhooly2016-27193287, author = {Gilhooly, K. J. and Gilhooly, M. L. and Sullivan, M. P. and McIntyre, A. and Wilson, L. and Harding, E. and Woodbridge, R. and Crutch, S.}, title = {{A meta-review of stress, coping and interventions in dementia and dementia caregiving}}, journal = {BMC geriatrics}, year = {2016}, doi = {10.1186/s12877-016-0280-8}, pmid = {27193287}, url = {https://doi.org/10.1186/s12877-016-0280-8} } @article{holstege2022-36411364, author = {Holstege, H. and Hulsman, M. and Charbonnier, C. and Grenier-Boley, B. and Quenez, O. and Grozeva, D. and van Rooij, J. G. J. and Sims, R. and others}, title = {{Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease}}, journal = {Nature genetics}, year = {2022}, doi = {10.1038/s41588-022-01208-7}, pmid = {36411364}, url = {https://doi.org/10.1038/s41588-022-01208-7} } @article{sampson2009-19567898, author = {Sampson, E. L. and Blanchard, M. R. and Jones, L. and Tookman, A. and King, M.}, title = {{Dementia in the acute hospital: prospective cohort study of prevalence and mortality}}, journal = {The British journal of psychiatry : the journal of mental science}, year = {2009}, doi = {10.1192/bjp.bp.108.055335}, pmid = {19567898}, url = {https://doi.org/10.1192/bjp.bp.108.055335} } @article{yu2022-35462001, author = {Yu, C. and Sommerlad, A. and Sakure, L. and Livingston, G.}, title = {{Socially assistive robots for people with dementia: Systematic review and meta-analysis of feasibility, acceptability and the effect on cognition, neuropsychiatric symptoms and quality of life}}, journal = {Ageing research reviews}, year = {2022}, doi = {10.1016/j.arr.2022.101633}, pmid = {35462001}, url = {https://doi.org/10.1016/j.arr.2022.101633} } @article{depablofernandez2019-30640364, author = {De Pablo-Fernández, E. and Lees, A. J. and Holton, J. L. and Warner, T. T.}, title = {{Prognosis and Neuropathologic Correlation of Clinical Subtypes of Parkinson Disease}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2018.4377}, pmid = {30640364}, url = {https://doi.org/10.1001/jamaneurol.2018.4377} } @article{hansson2018-29499171, author = {Hansson, O. and Seibyl, J. and Stomrud, E. and Zetterberg, H. and Trojanowski, J. Q. and Bittner, T. and Lifke, V. and Corradini, V. and others}, title = {{CSF biomarkers of Alzheimer's disease concord with amyloid-β PET and predict clinical progression: A study of fully automated immunoassays in BioFINDER and ADNI cohorts}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2018}, doi = {10.1016/j.jalz.2018.01.010}, pmid = {29499171}, url = {https://doi.org/10.1016/j.jalz.2018.01.010} } @article{elovainio2023-36669514, author = {Elovainio, M. and Komulainen, K. and Sipilä, P. N. and Pulkki-Råback, L. and Cachón Alonso, L. and Pentti, J. and Nyberg, S. T. and Suominen, S. and others}, title = {{Association of social isolation and loneliness with risk of incident hospital-treated infections: an analysis of data from the UK Biobank and Finnish Health and Social Support studies}}, journal = {The Lancet. Public health}, year = {2023}, doi = {10.1016/s2468-2667(22)00253-5}, pmid = {36669514}, url = {https://doi.org/10.1016/s2468-2667(22)00253-5} } @article{demnitzking2025-41130254, author = {Demnitz-King, H. and Adeleke, M. and Barber, J. A. and Poppe, M. and Budgett, J. and Alberts, S. and Duffy, L. and Minihane, A. M. and Gillings, R. and Chapman, H. and others}, title = {{Remote, lower-intensity, multidomain lifestyle intervention for subjective cognitive decline or mild cognitive impairment (APPLE-Tree): a multicentre, single-masked, randomised controlled trial}}, journal = {The Lancet Healthy Longevity}, year = {2025}, doi = {10.1016/j.lanhl.2025.100777}, pmid = {41130254}, url = {https://doi.org/10.1016/j.lanhl.2025.100777} } @article{penfold2026-41911932, author = {Penfold, Rose S and MacRae, Clare and Sampson, Elizabeth L and Davis, Daniel Hj and Anand, Atul and Ely, E Wesley and Guthrie, Bruce and MacLullich, Alasdair Mj}, title = {{Delirium, long-term conditions, and incident dementia in older adults admitted to hospital for emergency care in Lothian, Scotland: a population-based cohort study}}, journal = {The lancet. Healthy longevity}, year = {2026}, doi = {10.1016/j.lanhl.2026.100832}, pmid = {41911932}, url = {https://doi.org/10.1016/j.lanhl.2026.100832} } @article{sipila2026-41969011, author = {Sipilä, Pyry N and Pentti, Jaana and Frank, Philipp and Duggan, Michael R and Walker, Keenan A and Strandberg, Timo E and Lindbohm, Joni V and Kivimäki, Mika}, title = {{The role of frailty and comorbidities in severe infections and the risk of dementia: a prospective, multicohort, observational study}}, journal = {The lancet. Healthy longevity}, year = {2026}, doi = {10.1016/j.lanhl.2026.100826}, pmid = {41969011}, url = {https://doi.org/10.1016/j.lanhl.2026.100826} } @article{zetterberg2016-26524180, author = {Zetterberg, H. and Skillbäck, T. and Mattsson, N. and Trojanowski, J. Q. and Portelius, E. and Shaw, L. M. and Weiner, M. W. and Blennow, K. and others}, title = {{Association of Cerebrospinal Fluid Neurofilament Light Concentration With Alzheimer Disease Progression}}, journal = {JAMA neurology}, year = {2016}, doi = {10.1001/jamaneurol.2015.3037}, pmid = {26524180}, url = {https://doi.org/10.1001/jamaneurol.2015.3037} } @article{khalil2024-38609644, author = {Khalil, M. and Teunissen, C. E. and Lehmann, S. and Otto, M. and Piehl, F. and Ziemssen, T. and Bittner, S. and Sormani, M. P. and others}, title = {{Neurofilaments as biomarkers in neurological disorders - towards clinical application}}, journal = {Nature reviews. Neurology}, year = {2024}, doi = {10.1038/s41582-024-00955-x}, pmid = {38609644}, url = {https://doi.org/10.1038/s41582-024-00955-x} } @article{ossenkoppele2020-32091549, author = {Ossenkoppele, R. and Lyoo, C. H. and Jester-Broms, J. and Sudre, C. H. and Cho, H. and Ryu, Y. H. and Choi, J. Y. and Smith, R. and others}, title = {{Assessment of Demographic, Genetic, and Imaging Variables Associated With Brain Resilience and Cognitive Resilience to Pathological Tau in Patients With Alzheimer Disease}}, journal = {JAMA neurology}, year = {2020}, doi = {10.1001/jamaneurol.2019.5154}, pmid = {32091549}, url = {https://doi.org/10.1001/jamaneurol.2019.5154} } @article{ma2020-32575116, author = {Ma, Y. and Ajnakina, O. and Steptoe, A. and Cadar, D.}, title = {{Higher risk of dementia in English older individuals who are overweight or obese}}, journal = {International journal of epidemiology}, year = {2020}, doi = {10.1093/ije/dyaa099}, pmid = {32575116}, url = {https://doi.org/10.1093/ije/dyaa099} } @article{waldemar2007-17222085, author = {Waldemar, G. and Dubois, B. and Emre, M. and Georges, J. and McKeith, I. G. and Rossor, M. and Scheltens, P. and Tariska, P. and others}, title = {{Recommendations for the diagnosis and management of Alzheimer's disease and other disorders associated with dementia: EFNS guideline}}, journal = {European journal of neurology}, year = {2007}, doi = {10.1111/j.1468-1331.2006.01605.x}, pmid = {17222085}, url = {https://doi.org/10.1111/j.1468-1331.2006.01605.x} } @article{shirzadi2023-37843849, author = {Shirzadi, Z. and Schultz, S. A. and Yau, W. W. and Joseph-Mathurin, N. and Fitzpatrick, C. D. and Levin, R. and Kantarci, K. and Preboske, G. M. and others}, title = {{Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.3618}, pmid = {37843849}, url = {https://doi.org/10.1001/jamaneurol.2023.3618} } @article{gibb2020-32239173, author = {Gibb, K. and Seeley, A. and Quinn, T. and Siddiqi, N. and Shenkin, S. and Rockwood, K. and Davis, D.}, title = {{The consistent burden in published estimates of delirium occurrence in medical inpatients over four decades: a systematic review and meta-analysis study}}, journal = {Age and ageing}, year = {2020}, doi = {10.1093/ageing/afaa040}, pmid = {32239173}, url = {https://doi.org/10.1093/ageing/afaa040} } @article{delgadosaborit2021-33340865, author = {Delgado-Saborit, J. M. and Guercio, V. and Gowers, A. M. and Shaddick, G. and Fox, N. C. and Love, S.}, title = {{A critical review of the epidemiological evidence of effects of air pollution on dementia, cognitive function and cognitive decline in adult population}}, journal = {The Science of the total environment}, year = {2021}, doi = {10.1016/j.scitotenv.2020.143734}, pmid = {33340865}, url = {https://doi.org/10.1016/j.scitotenv.2020.143734} } @article{majounie2012-22406228, author = {Majounie, E. and Renton, A. E. and Mok, K. and Dopper, E. G. and Waite, A. and Rollinson, S. and Chiò, A. and Restagno, G. and others}, title = {{Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study}}, journal = {The Lancet. Neurology}, year = {2012}, doi = {10.1016/s1474-4422(12)70043-1}, pmid = {22406228}, url = {https://doi.org/10.1016/s1474-4422(12)70043-1} } @article{cooper2010-20224516, author = {Cooper, C. and Tandy, A. R. and Balamurali, T. B. and Livingston, G.}, title = {{A systematic review and meta-analysis of ethnic differences in use of dementia treatment, care, and research}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2010}, doi = {10.1097/jgp.0b013e3181bf9caf}, pmid = {20224516}, url = {https://doi.org/10.1097/jgp.0b013e3181bf9caf} } @article{young2018-30323170, author = {Young, A. L. and Marinescu, R. V. and Oxtoby, N. P. and Bocchetta, M. and Yong, K. and Firth, N. C. and Cash, D. M. and Thomas, D. L. and others}, title = {{Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference}}, journal = {Nature communications}, year = {2018}, doi = {10.1038/s41467-018-05892-0}, pmid = {30323170}, url = {https://doi.org/10.1038/s41467-018-05892-0} } @article{vanderroest2017-28602027, author = {Van der Roest, H. G. and Wenborn, J. and Pastink, C. and Dröes, R. M. and Orrell, M.}, title = {{Assistive technology for memory support in dementia}}, journal = {The Cochrane database of systematic reviews}, year = {2017}, doi = {10.1002/14651858.cd009627.pub2}, pmid = {28602027}, url = {https://doi.org/10.1002/14651858.cd009627.pub2} } @article{hippisleycox2021-34535466, author = {Hippisley-Cox, J. and Coupland, C. A. and Mehta, N. and Keogh, R. H. and Diaz-Ordaz, K. and Khunti, K. and Lyons, R. A. and Kee, F. and others}, title = {{Risk prediction of covid-19 related death and hospital admission in adults after covid-19 vaccination: national prospective cohort study}}, journal = {BMJ (Clinical research ed.)}, year = {2021}, doi = {10.1136/bmj.n2244}, pmid = {34535466}, url = {https://doi.org/10.1136/bmj.n2244} } @article{slot2018-30081935, author = {Slot, R. E. R. and Verfaillie, S. C. J. and Overbeek, J. M. and Timmers, T. and Wesselman, L. M. P. and Teunissen, C. E. and Dols, A. and Bouwman, F. H. and others}, title = {{Subjective Cognitive Impairment Cohort (SCIENCe): study design and first results}}, journal = {Alzheimer's research \& therapy}, year = {2018}, doi = {10.1186/s13195-018-0390-y}, pmid = {30081935}, url = {https://doi.org/10.1186/s13195-018-0390-y} } @article{oxtoby2018-29579160, author = {Oxtoby, N. P. and Young, A. L. and Cash, D. M. and Benzinger, T. L. S. and Fagan, A. M. and Morris, J. C. and Bateman, R. J. and Fox, N. C. and others}, title = {{Data-driven models of dominantly-inherited Alzheimer's disease progression}}, journal = {Brain : a journal of neurology}, year = {2018}, doi = {10.1093/brain/awy050}, pmid = {29579160}, url = {https://doi.org/10.1093/brain/awy050} } @article{cullen2021-37117993, author = {Cullen, N. C. and Leuzy, A. and Palmqvist, S. and Janelidze, S. and Stomrud, E. and Pesini, P. and Sarasa, L. and Allué, J. A. and others}, title = {{Individualized prognosis of cognitive decline and dementia in mild cognitive impairment based on plasma biomarker combinations}}, journal = {Nature aging}, year = {2021}, doi = {10.1038/s43587-020-00003-5}, pmid = {37117993}, url = {https://doi.org/10.1038/s43587-020-00003-5} } @article{lane2020-31682678, author = {Lane, C. A. and Barnes, J. and Nicholas, J. M. and Sudre, C. H. and Cash, D. M. and Malone, I. B. and Parker, T. D. and Keshavan, A. and others}, title = {{Associations Between Vascular Risk Across Adulthood and Brain Pathology in Late Life: Evidence From a British Birth Cohort}}, journal = {JAMA neurology}, year = {2020}, doi = {10.1001/jamaneurol.2019.3774}, pmid = {31682678}, url = {https://doi.org/10.1001/jamaneurol.2019.3774} } @article{wang2024-37988283, author = {Wang, Y. T. and Therriault, J. and Servaes, S. and Tissot, C. and Rahmouni, N. and Macedo, A. C. and Fernandez-Arias, J. and Mathotaarachchi, S. S. and others}, title = {{Sex-specific modulation of amyloid-β on tau phosphorylation underlies faster tangle accumulation in females}}, journal = {Brain : a journal of neurology}, year = {2024}, doi = {10.1093/brain/awad397}, pmid = {37988283}, url = {https://doi.org/10.1093/brain/awad397} } @article{gregson2025-40921943, author = {Gregson, Celia Louise and Armstrong, David and Avgerinou, Christina and Bowden, Jean and Cooper, Cyrus and Douglas, Lucy and Edwards, John and Gittoes, Neil J. L. and others}, title = {{The 2024 UK clinical guideline for the prevention and treatment of osteoporosis}}, journal = {Archives of Osteoporosis}, year = {2025}, doi = {10.1007/s11657-025-01588-3}, pmid = {40921943}, url = {https://doi.org/10.1007/s11657-025-01588-3} } @article{livingston2020-32738937, author = {Livingston, Gill and Huntley, Jonathan D. and Sommerlad, Andrew and Ames, David and Ballard, Clive G. and Banerjee, Sube and Brayne, Carol and Burns, Alistair S. and others}, title = {{Dementia prevention, intervention, and care: 2020 report of the Lancet Commission}}, journal = {The Lancet}, year = {2020}, doi = {10.1016/s0140-6736(20)30367-6}, pmid = {32738937}, url = {https://doi.org/10.1016/s0140-6736(20)30367-6} } @article{jansen2019-30617256, author = {Jansen, Iris E. and Savage, Jeanne E. and Watanabe, Kyoko and Bryois, Julien and Williams, Dylan M. and Steinberg, Stacy and Sealock, Julia and Karlsson, Ida and others}, title = {{Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk}}, journal = {Nature Genetics}, year = {2019}, doi = {10.1038/s41588-018-0311-9}, pmid = {30617256}, url = {https://doi.org/10.1038/s41588-018-0311-9} } @article{melville2025-41448220, author = {Melville, M. and He, L. and Desai, R. and Nyamayaro, P. and Fox, C. and Kothari, K. U. and Condron, P. and Miao, M. and Hickey, M. and Spector, A.}, title = {{Menopause hormone therapy and risk of mild cognitive impairment or dementia: a systematic review and meta-analysis}}, journal = {The Lancet Healthy Longevity}, year = {2025}, doi = {10.1016/j.lanhl.2025.100803}, pmid = {41448220}, url = {https://doi.org/10.1016/j.lanhl.2025.100803} } @article{ferrarisouza2026-41198899, author = {Ferrari-Souza, J. P. and Povala, G. and Rahmouni, N. and Bellaver, B. and Ferreira, P. C. L. and De Bastiani, M. A. and Leffa, D. T. and Lussier, F. Z. and Aguzzoli, C. S. and Brum, W. S. and Carello-Collar, G. and Borelli, W. V. and others}, title = {{Microglia modulate Aβ-dependent astrocyte reactivity in Alzheimer's disease}}, journal = {Nature Neuroscience}, year = {2026}, doi = {10.1038/s41593-025-02103-0}, pmid = {41198899}, url = {https://doi.org/10.1038/s41593-025-02103-0} } @article{liu2015-26208959, author = {Liu, E. and Schmidt, M. E. and Margolin, R. and Sperling, R. and Koeppe, R. and Mason, N. S. and Klunk, W. E. and Mathis, C. A. and others}, title = {{Amyloid-β 11C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials}}, journal = {Neurology}, year = {2015}, doi = {10.1212/wnl.0000000000001877}, pmid = {26208959}, url = {https://doi.org/10.1212/wnl.0000000000001877} } @article{vandepol2007-17620494, author = {van de Pol, L. A. and Korf, E. S. and van der Flier, W. M. and Brashear, H. R. and Fox, N. C. and Barkhof, F. and Scheltens, P.}, title = {{Magnetic resonance imaging predictors of cognition in mild cognitive impairment}}, journal = {Archives of neurology}, year = {2007}, doi = {10.1001/archneur.64.7.1023}, pmid = {17620494}, url = {https://doi.org/10.1001/archneur.64.7.1023} } @article{cooper2015-25698435, author = {Cooper, C. and Sommerlad, A. and Lyketsos, C. G. and Livingston, G.}, title = {{Modifiable predictors of dementia in mild cognitive impairment: a systematic review and meta-analysis}}, journal = {The American journal of psychiatry}, year = {2015}, doi = {10.1176/appi.ajp.2014.14070878}, pmid = {25698435}, url = {https://doi.org/10.1176/appi.ajp.2014.14070878} } @article{yates2016-27502691, author = {Yates, L. A. and Ziser, S. and Spector, A. and Orrell, M.}, title = {{Cognitive leisure activities and future risk of cognitive impairment and dementia: systematic review and meta-analysis}}, journal = {International psychogeriatrics}, year = {2016}, doi = {10.1017/s1041610216001137}, pmid = {27502691}, url = {https://doi.org/10.1017/s1041610216001137} } @article{hye2006-17071923, author = {Hye, A. and Lynham, S. and Thambisetty, M. and Causevic, M. and Campbell, J. and Byers, H. L. and Hooper, C. and Rijsdijk, F. and others}, title = {{Proteome-based plasma biomarkers for Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2006}, doi = {10.1093/brain/awl279}, pmid = {17071923}, url = {https://doi.org/10.1093/brain/awl279} } @article{olazaran2010-20838046, author = {Olazarán, J. and Reisberg, B. and Clare, L. and Cruz, I. and Peña-Casanova, J. and Del Ser, T. and Woods, B. and Beck, C. and others}, title = {{Nonpharmacological therapies in Alzheimer's disease: a systematic review of efficacy}}, journal = {Dementia and geriatric cognitive disorders}, year = {2010}, doi = {10.1159/000316119}, pmid = {20838046}, url = {https://doi.org/10.1159/000316119} } @article{feast2016-26989095, author = {Feast, A. and Orrell, M. and Charlesworth, G. and Melunsky, N. and Poland, F. and Moniz-Cook, E.}, title = {{Behavioural and psychological symptoms in dementia and the challenges for family carers: systematic review}}, journal = {The British journal of psychiatry : the journal of mental science}, year = {2016}, doi = {10.1192/bjp.bp.114.153684}, pmid = {26989095}, url = {https://doi.org/10.1192/bjp.bp.114.153684} } @article{pham2018-30123007, author = {Pham, T. M. and Petersen, I. and Walters, K. and Raine, R. and Manthorpe, J. and Mukadam, N. and Cooper, C.}, title = {{Trends in dementia diagnosis rates in UK ethnic groups: analysis of UK primary care data}}, journal = {Clinical epidemiology}, year = {2018}, doi = {10.2147/clep.s152647}, pmid = {30123007}, url = {https://doi.org/10.2147/clep.s152647} } @article{bloomberg2021-33516287, author = {Bloomberg, M. and Dugravot, A. and Dumurgier, J. and Kivimaki, M. and Fayosse, A. and Steptoe, A. and Britton, A. and Singh-Manoux, A. and others}, title = {{Sex differences and the role of education in cognitive ageing: analysis of two UK-based prospective cohort studies}}, journal = {The Lancet. Public health}, year = {2021}, doi = {10.1016/s2468-2667(20)30258-9}, pmid = {33516287}, url = {https://doi.org/10.1016/s2468-2667(20)30258-9} } @article{wellington2016-26826204, author = {Wellington, H. and Paterson, R. W. and Portelius, E. and Törnqvist, U. and Magdalinou, N. and Fox, N. C. and Blennow, K. and Schott, J. M. and others}, title = {{Increased CSF neurogranin concentration is specific to Alzheimer disease}}, journal = {Neurology}, year = {2016}, doi = {10.1212/wnl.0000000000002423}, pmid = {26826204}, url = {https://doi.org/10.1212/wnl.0000000000002423} } @article{martin2023-36735865, author = {Martin, S. A. and Townend, F. J. and Barkhof, F. and Cole, J. H.}, title = {{Interpretable machine learning for dementia: A systematic review}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2023}, doi = {10.1002/alz.12948}, pmid = {36735865}, url = {https://doi.org/10.1002/alz.12948} } @article{vandeerlin2010-20154673, author = {Van Deerlin, V. M. and Sleiman, P. M. and Martinez-Lage, M. and Chen-Plotkin, A. and Wang, L. S. and Graff-Radford, N. R. and Dickson, D. W. and Rademakers, R. and others}, title = {{Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions}}, journal = {Nature genetics}, year = {2010}, doi = {10.1038/ng.536}, pmid = {20154673}, url = {https://doi.org/10.1038/ng.536} } @article{gonzalez2022-34807233, author = {Gonzalez, M. C. and Ashton, N. J. and Gomes, B. F. and Tovar-Rios, D. A. and Blanc, F. and Karikari, T. K. and Mollenhauer, B. and Pilotto, A. and others}, title = {{Association of Plasma p-tau181 and p-tau231 Concentrations With Cognitive Decline in Patients With Probable Dementia With Lewy Bodies}}, journal = {JAMA neurology}, year = {2022}, doi = {10.1001/jamaneurol.2021.4222}, pmid = {34807233}, url = {https://doi.org/10.1001/jamaneurol.2021.4222} } @article{ghahremani2023-36323521, author = {Ghahremani, M. and Wang, M. and Chen, H. Y. and Zetterberg, H. and Smith, E. and Ismail, Z. and {Alzheimer's Disease Neuroimaging Initiative*}}, title = {{Plasma Phosphorylated Tau at Threonine 181 and Neuropsychiatric Symptoms in Preclinical and Prodromal Alzheimer Disease}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000201517}, pmid = {36323521}, url = {https://doi.org/10.1212/wnl.0000000000201517} } @article{saddiki2020-32817639, author = {Saddiki, H. and Fayosse, A. and Cognat, E. and Sabia, S. and Engelborghs, S. and Wallon, D. and Alexopoulos, P. and Blennow, K. and others}, title = {{Age and the association between apolipoprotein E genotype and Alzheimer disease: A cerebrospinal fluid biomarker-based case-control study}}, journal = {PLoS medicine}, year = {2020}, doi = {10.1371/journal.pmed.1003289}, pmid = {32817639}, url = {https://doi.org/10.1371/journal.pmed.1003289} } @article{yu2025-39835654, author = {Yu, Ruan‐Ching and Pavlou, Menelaos and Schilder, Anne GM and Bamiou, Doris‐Eva and Lewis, Glyn and Lin, Frank Robert and Livingston, Gill and Proctor, Danielle and others}, title = {{Early detection and management of hearing loss to reduce dementia risk in older adults with mild cognitive impairment: findings from the treating auditory impairment and cognition trial (TACT)}}, journal = {Age and Ageing}, year = {2025}, doi = {10.1093/ageing/afaf004}, pmid = {39835654}, url = {https://doi.org/10.1093/ageing/afaf004} } @article{lambert2013-24162737, author = {Lambert, Jean‐Charles and Ibrahim‐Verbaas, Carla A. and Harold, Denise H. and Naj, Adam Christian and Sims, Rebecca and Bellenguez, Céline and others}, title = {{Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease}}, journal = {Nature Genetics}, year = {2013}, doi = {10.1038/ng.2802}, pmid = {24162737}, url = {https://doi.org/10.1038/ng.2802} } @article{dubois2014-24849862, author = {Dubois, Bruno and Feldman, Howard and Jacova, Claudia and Hampel, Harald Juergen and Molinuevo, José Luís and Blennow, Kaj and DeKosky, Steven T. and Gauthier, Serge G. and others}, title = {{Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria}}, journal = {The Lancet Neurology}, year = {2014}, doi = {10.1016/s1474-4422(14)70090-0}, pmid = {24849862}, url = {https://doi.org/10.1016/s1474-4422(14)70090-0} } @article{harold2009-19734902, author = {Harold, Denise H. and Abraham, Richard and Hollingworth, Paul and Sims, Rebecca and Gerrish, Amy and Hamshere, Marian L. and Pahwa, Jaspreet Singh and Moskvina, Valentina and others}, title = {{Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease}}, journal = {Nature Genetics}, year = {2009}, doi = {10.1038/ng.440}, pmid = {19734902}, url = {https://doi.org/10.1038/ng.440} } @article{study2011-21460840, author = {{the Alzheimer's Disease Neuroimaging Initiative} and Hollingworth, Paul and Harold, Denise H. and Sims, Rebecca and Gerrish, Amy and Lambert, Jean‐Charles and Carrasquillo, Minerva M. and Abraham, Richard and others}, title = {{Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease}}, journal = {Nature Genetics}, year = {2011}, doi = {10.1038/ng.803}, pmid = {21460840}, url = {https://doi.org/10.1038/ng.803} } @article{yun2026-41627837, author = {Yun, Jihwan and Lee, Jungah and Shin, Daeun and Lee, Eun Hye and Kim, Jun Pyo and Ham, Hongki and Gu, Yuna and Chun, Min Young and others}, title = {{Plasma Phosphorylated Tau 217 Cutoffs for Amyloid Pathology and Kidney Function, Body Mass Index, and Anemia}}, journal = {JAMA neurology}, year = {2026}, doi = {10.1001/jamaneurol.2025.5530}, pmid = {41627837}, url = {https://doi.org/10.1001/jamaneurol.2025.5530} } @article{giorgio2026-41936382, author = {Giorgio, Katherine and Stephen, John J and Mansolf, Maxwell and Peterson, Elizabeth A and Gross, Alden L and Briceño, Emily M and Levine, Deborah A and Helmer, Catherine and others}, title = {{Risk factors for early-onset and late-onset dementia: a prospective cohort study}}, journal = {The lancet. Healthy longevity}, year = {2026}, doi = {10.1016/j.lanhl.2026.100831}, pmid = {41936382}, url = {https://doi.org/10.1016/j.lanhl.2026.100831} } @article{mielke2021-34309632, author = {Mielke, M. M. and Frank, R. D. and Dage, J. L. and Jeromin, A. and Ashton, N. J. and Blennow, K. and Karikari, T. K. and Vanmechelen, E. and others}, title = {{Comparison of Plasma Phosphorylated Tau Species With Amyloid and Tau Positron Emission Tomography, Neurodegeneration, Vascular Pathology, and Cognitive Outcomes}}, journal = {JAMA neurology}, year = {2021}, doi = {10.1001/jamaneurol.2021.2293}, pmid = {34309632}, url = {https://doi.org/10.1001/jamaneurol.2021.2293} } @article{weston2017-29070659, author = {Weston, P. S. J. and Poole, T. and Ryan, N. S. and Nair, A. and Liang, Y. and Macpherson, K. and Druyeh, R. and Malone, I. B. and others}, title = {{Serum neurofilament light in familial Alzheimer disease: A marker of early neurodegeneration}}, journal = {Neurology}, year = {2017}, doi = {10.1212/wnl.0000000000004667}, pmid = {29070659}, url = {https://doi.org/10.1212/wnl.0000000000004667} } @article{illangala2021-33199433, author = {Illán-Gala, I. and Lleo, A. and Karydas, A. and Staffaroni, A. M. and Zetterberg, H. and Sivasankaran, R. and Grinberg, L. T. and Spina, S. and others}, title = {{Plasma Tau and Neurofilament Light in Frontotemporal Lobar Degeneration and Alzheimer Disease}}, journal = {Neurology}, year = {2021}, doi = {10.1212/wnl.0000000000011226}, pmid = {33199433}, url = {https://doi.org/10.1212/wnl.0000000000011226} } @article{josephmathurin2022-36151869, author = {Joseph-Mathurin, N. and Llibre-Guerra, J. J. and Li, Y. and McCullough, A. A. and Hofmann, C. and Wojtowicz, J. and Park, E. and Wang, G. and others}, title = {{Amyloid-Related Imaging Abnormalities in the DIAN-TU-001 Trial of Gantenerumab and Solanezumab: Lessons from a Trial in Dominantly Inherited Alzheimer Disease}}, journal = {Annals of neurology}, year = {2022}, doi = {10.1002/ana.26511}, pmid = {36151869}, url = {https://doi.org/10.1002/ana.26511} } @article{yun2025-39960728, author = {Yun, J. and Shin, D. and Lee, E. H. and Kim, J. P. and Ham, H. and Gu, Y. and Chun, M. Y. and Kang, S. H. and others}, title = {{Temporal Dynamics and Biological Variability of Alzheimer Biomarkers}}, journal = {JAMA neurology}, year = {2025}, doi = {10.1001/jamaneurol.2024.5263}, pmid = {39960728}, url = {https://doi.org/10.1001/jamaneurol.2024.5263} } @article{gogniat2025-40561381, author = {Gogniat, M. A. and Khan, O. A. and Ratangee, B. and Bolton, C. J. and Zhang, P. and Liu, D. and Pechman, K. R. and Yates, A. and others}, title = {{Cross-Sectional and Longitudinal Associations of Neighborhood Disadvantage With Fluid Biomarkers of Neuroinflammation and Neurodegeneration}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000213770}, pmid = {40561381}, url = {https://doi.org/10.1212/wnl.0000000000213770} } @article{vermunt2019-31164314, author = {Vermunt, L. and Sikkes, S. A. M. and van den Hout, A. and Handels, R. and Bos, I. and van der Flier, W. M. and Kern, S. and Ousset, P. J. and others}, title = {{Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2019}, doi = {10.1016/j.jalz.2019.04.001}, pmid = {31164314}, url = {https://doi.org/10.1016/j.jalz.2019.04.001} } @article{demnitzking2023-37450303, author = {Demnitz-King, H. and Requier, F. and Whitfield, T. and Schlosser, M. and Gonneaud, J. and Ware, C. and Barnhofer, T. and Coll-Padros, N. and others}, title = {{Effects of Meditation Training and Non-Native Language Training on Cognition in Older Adults: A Secondary Analysis of a Randomized Clinical Trial}}, journal = {JAMA network open}, year = {2023}, doi = {10.1001/jamanetworkopen.2023.17848}, pmid = {37450303}, url = {https://doi.org/10.1001/jamanetworkopen.2023.17848} } @article{scheltens2021-33667416, author = {Scheltens, P. and De Strooper, B. and Kivipelto, M. and Holstege, H. and Chételat, G. and Teunissen, C. E. and Cummings, J. and van der Flier, W. M.}, title = {{Alzheimer's disease}}, journal = {Lancet (London, England)}, year = {2021}, doi = {10.1016/s0140-6736(20)32205-4}, pmid = {33667416}, url = {https://doi.org/10.1016/s0140-6736(20)32205-4} } @article{dimarco2014-24799342, author = {Di Marco, L. Y. and Marzo, A. and Muñoz-Ruiz, M. and Ikram, M. A. and Kivipelto, M. and Ruefenacht, D. and Venneri, A. and Soininen, H. and others}, title = {{Modifiable lifestyle factors in dementia: a systematic review of longitudinal observational cohort studies}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2014}, doi = {10.3233/jad-132225}, pmid = {24799342}, url = {https://doi.org/10.3233/jad-132225} } @article{rascovsky2011-21810890, author = {Rascovsky, K. and Hodges, JR. and Knopman, D. and Mendez, M. F. and Kramer, J. H. and Neuhaus, J. and van Swieten, J. C. and Seelaar, H. and others}, title = {{Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia}}, journal = {Brain : a journal of neurology}, year = {2011}, doi = {10.1093/brain/awr179}, pmid = {21810890}, url = {https://doi.org/10.1093/brain/awr179} } @article{hamer2009-18570697, author = {Hamer, M. and Chida, Y.}, title = {{Physical activity and risk of neurodegenerative disease: a systematic review of prospective evidence}}, journal = {Psychological medicine}, year = {2009}, doi = {10.1017/s0033291708003681}, pmid = {18570697}, url = {https://doi.org/10.1017/s0033291708003681} } @article{thijssen2021-34418401, author = {Thijssen, E. H. and La Joie, R. and Strom, A. and Fonseca, C. and Iaccarino, L. and Wolf, A. and Spina, S. and Allen, I. E. and others}, title = {{Plasma phosphorylated tau 217 and phosphorylated tau 181 as biomarkers in Alzheimer's disease and frontotemporal lobar degeneration: a retrospective diagnostic performance study}}, journal = {The Lancet. Neurology}, year = {2021}, doi = {10.1016/s1474-4422(21)00214-3}, pmid = {34418401}, url = {https://doi.org/10.1016/s1474-4422(21)00214-3} } @article{trzepacz2015-26346644, author = {Trzepacz, P. T. and Hochstetler, H. and Wang, S. and Walker, B. and Saykin, A. J. and {Alzheimer’s Disease Neuroimaging Initiative}}, title = {{Relationship between the Montreal Cognitive Assessment and Mini-mental State Examination for assessment of mild cognitive impairment in older adults}}, journal = {BMC geriatrics}, year = {2015}, doi = {10.1186/s12877-015-0103-3}, pmid = {26346644}, url = {https://doi.org/10.1186/s12877-015-0103-3} } @article{rohrer2009-19884572, author = {Rohrer, J. D. and Guerreiro, R. and Vandrovcova, J. and Uphill, J. and Reiman, D. and Beck, J. and Isaacs, A. M. and Authier, A. and others}, title = {{The heritability and genetics of frontotemporal lobar degeneration}}, journal = {Neurology}, year = {2009}, doi = {10.1212/wnl.0b013e3181bf997a}, pmid = {19884572}, url = {https://doi.org/10.1212/wnl.0b013e3181bf997a} } @article{vandepol2007-17923611, author = {van de Pol, L. A. and van der Flier, W. M. and Korf, E. S. and Fox, N. C. and Barkhof, F. and Scheltens, P.}, title = {{Baseline predictors of rates of hippocampal atrophy in mild cognitive impairment}}, journal = {Neurology}, year = {2007}, doi = {10.1212/01.wnl.0000277458.26846.96}, pmid = {17923611}, url = {https://doi.org/10.1212/01.wnl.0000277458.26846.96} } @article{livingston2005-16263837, author = {Livingston, G. and Johnston, K. and Katona, C. and Paton, J. and Lyketsos, C. G. and {Old Age Task Force of the World Federation of Biological Psychiatry}}, title = {{Systematic review of psychological approaches to the management of neuropsychiatric symptoms of dementia}}, journal = {The American journal of psychiatry}, year = {2005}, doi = {10.1176/appi.ajp.162.11.1996}, pmid = {16263837}, url = {https://doi.org/10.1176/appi.ajp.162.11.1996} } @article{turner2004-15271637, author = {Turner, S. and Iliffe, S. and Downs, M. and Wilcock, J. and Bryans, M. and Levin, E. and Keady, J. and O'Carroll, R.}, title = {{General practitioners' knowledge, confidence and attitudes in the diagnosis and management of dementia}}, journal = {Age and ageing}, year = {2004}, doi = {10.1093/ageing/afh140}, pmid = {15271637}, url = {https://doi.org/10.1093/ageing/afh140} } @article{benedet2020-33210117, author = {Benedet, A. L. and Leuzy, A. and Pascoal, T. A. and Ashton, N. J. and Mathotaarachchi, S. and Savard, M. and Therriault, J. and Kang, M. S. and others}, title = {{Stage-specific links between plasma neurofilament light and imaging biomarkers of Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2020}, doi = {10.1093/brain/awaa342}, pmid = {33210117}, url = {https://doi.org/10.1093/brain/awaa342} } @article{nguyen2020-32763427, author = {Nguyen, M. and He, T. and An, L. and Alexander, D. C. and Feng, J. and Yeo, B. T. T. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{Predicting Alzheimer's disease progression using deep recurrent neural networks}}, journal = {NeuroImage}, year = {2020}, doi = {10.1016/j.neuroimage.2020.117203}, pmid = {32763427}, url = {https://doi.org/10.1016/j.neuroimage.2020.117203} } @article{duff2025-39885359, author = {Duff, E. P. and Zetterberg, H. and Heslegrave, A. and Dehghan, A. and Elliott, P. and Allen, N. and Runz, H. and Laban, R. and others}, title = {{Plasma proteomic evidence for increased β-amyloid pathology after SARS-CoV-2 infection}}, journal = {Nature medicine}, year = {2025}, doi = {10.1038/s41591-024-03426-4}, pmid = {39885359}, url = {https://doi.org/10.1038/s41591-024-03426-4} } @article{silvarodriguez2025-39888600, author = {Silva‐Rodríguez, Jesús and Labrador‐Espinosa, Miguel Ángel and Zhang, Linda and Castro‐Labrador, Sandra and López‐González, Francisco Javier and Moscoso, Alexis and Sánchez‐Juan, Pascual and Schöll, Michael and others}, title = {{The effect of Lewy body (co-)pathology on the clinical and imaging phenotype of amnestic patients}}, journal = {Brain}, year = {2025}, doi = {10.1093/brain/awaf037}, pmid = {39888600}, url = {https://doi.org/10.1093/brain/awaf037} } @article{livingston2017-28735855, author = {Livingston, Gill and Sommerlad, Andrew and Orgeta, Vasiliki and Costafreda, Sergi G. and Huntley, Jonathan D. and Ames, David and Ballard, Clive G. and Banerjee, Sube and others}, title = {{Dementia prevention, intervention, and care}}, journal = {The Lancet}, year = {2017}, doi = {10.1016/s0140-6736(17)31363-6}, pmid = {28735855}, url = {https://doi.org/10.1016/s0140-6736(17)31363-6} } @article{ebenau2020-32522798, author = {Ebenau, J. L. and Timmers, T. and Wesselman, L. M. P. and Verberk, I. M. W. and Verfaillie, S. C. J. and Slot, R. E. R. and van Harten, A. C. and Teunissen, C. E. and others}, title = {{ATN classification and clinical progression in subjective cognitive decline: The SCIENCe project}}, journal = {Neurology}, year = {2020}, doi = {10.1212/wnl.0000000000009724}, pmid = {32522798}, url = {https://doi.org/10.1212/wnl.0000000000009724} } @article{bejanin2021-34228042, author = {Bejanin, A. and Iulita, M. F. and Vilaplana, E. and Carmona-Iragui, M. and Benejam, B. and Videla, L. and Barroeta, I. and Fernandez, S. and others}, title = {{Association of Apolipoprotein E ɛ4 Allele With Clinical and Multimodal Biomarker Changes of Alzheimer Disease in Adults With Down Syndrome}}, journal = {JAMA neurology}, year = {2021}, doi = {10.1001/jamaneurol.2021.1893}, pmid = {34228042}, url = {https://doi.org/10.1001/jamaneurol.2021.1893} } @article{martinoadami2024-39253733, author = {Martino-Adami, P. V. and Chatterjee, M. and Kleineidam, L. and Weyerer, S. and Bickel, H. and Wiese, B. and Riedel-Heller, S. G. and Scherer, M. and others}, title = {{Prognostic value of Alzheimer's disease plasma biomarkers in the oldest-old: a prospective primary care-based study}}, journal = {The Lancet regional health. Europe}, year = {2024}, doi = {10.1016/j.lanepe.2024.101030}, pmid = {39253733}, url = {https://doi.org/10.1016/j.lanepe.2024.101030} } @article{mckeith2005-16237129, author = {McKeith, I. G. and Dickson, D. W. and Lowe, J. and Emre, M. and O'Brien, J. T. and Feldman, H. and Cummings, J. and Duda, J. E. and others}, title = {{Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium}}, journal = {Neurology}, year = {2005}, doi = {10.1212/01.wnl.0000187889.17253.b1}, pmid = {16237129}, url = {https://doi.org/10.1212/01.wnl.0000187889.17253.b1} } @article{scheltens2016-26921134, author = {Scheltens, P. and Blennow, K. and Breteler, M. M. and de Strooper, B. and Frisoni, G. B. and Salloway, S. and Van der Flier, W. M.}, title = {{Alzheimer's disease}}, journal = {Lancet (London, England)}, year = {2016}, doi = {10.1016/s0140-6736(15)01124-1}, pmid = {26921134}, url = {https://doi.org/10.1016/s0140-6736(15)01124-1} } @article{yang2022-36108674, author = {Yang, Y. and Shi, Y. and Schweighauser, M. and Zhang, X. and Kotecha, A. and Murzin, A. G. and Garringer, H. J. and Cullinane, P. W. and others}, title = {{Structures of α-synuclein filaments from human brains with Lewy pathology}}, journal = {Nature}, year = {2022}, doi = {10.1038/s41586-022-05319-3}, pmid = {36108674}, url = {https://doi.org/10.1038/s41586-022-05319-3} } @article{banerjee2011-21764118, author = {Banerjee, S. and Hellier, J. and Dewey, M. and Romeo, R. and Ballard, C. and Baldwin, R. and Bentham, P. and Fox, C. and others}, title = {{Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial}}, journal = {Lancet (London, England)}, year = {2011}, doi = {10.1016/s0140-6736(11)60830-1}, pmid = {21764118}, url = {https://doi.org/10.1016/s0140-6736(11)60830-1} } @article{feast2016-27345942, author = {Feast, A. and Moniz-Cook, E. and Stoner, C. and Charlesworth, G. and Orrell, M.}, title = {{A systematic review of the relationship between behavioral and psychological symptoms (BPSD) and caregiver well-being}}, journal = {International psychogeriatrics}, year = {2016}, doi = {10.1017/s1041610216000922}, pmid = {27345942}, url = {https://doi.org/10.1017/s1041610216000922} } @article{janelidze2016-27241045, author = {Janelidze, S. and Stomrud, E. and Palmqvist, S. and Zetterberg, H. and van Westen, D. and Jeromin, A. and Song, L. and Hanlon, D. and others}, title = {{Plasma β-amyloid in Alzheimer's disease and vascular disease}}, journal = {Scientific reports}, year = {2016}, doi = {10.1038/srep26801}, pmid = {27241045}, url = {https://doi.org/10.1038/srep26801} } @article{neumann2009-19286695, author = {Neumann, J. and Bras, J. and Deas, E. and O'Sullivan, S. S. and Parkkinen, L. and Lachmann, R. H. and Li, A. and Holton, J. and others}, title = {{Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease}}, journal = {Brain : a journal of neurology}, year = {2009}, doi = {10.1093/brain/awp044}, pmid = {19286695}, url = {https://doi.org/10.1093/brain/awp044} } @article{thijssen2020-32123386, author = {Thijssen, E. H. and La Joie, R. and Wolf, A. and Strom, A. and Wang, P. and Iaccarino, L. and Bourakova, V. and Cobigo, Y. and others}, title = {{Diagnostic value of plasma phosphorylated tau181 in Alzheimer's disease and frontotemporal lobar degeneration}}, journal = {Nature medicine}, year = {2020}, doi = {10.1038/s41591-020-0762-2}, pmid = {32123386}, url = {https://doi.org/10.1038/s41591-020-0762-2} } @article{brown2022-35197628, author = {Brown, A. L. and Wilkins, O. G. and Keuss, M. J. and Kargbo-Hill, S. E. and Zanovello, M. and Lee, W. C. and Bampton, A. and Lee, F. C. Y. and others}, title = {{TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A}}, journal = {Nature}, year = {2022}, doi = {10.1038/s41586-022-04436-3}, pmid = {35197628}, url = {https://doi.org/10.1038/s41586-022-04436-3} } @article{chia2021-33589841, author = {Chia, R. and Sabir, M. S. and Bandres-Ciga, S. and Saez-Atienzar, S. and Reynolds, R. H. and Gustavsson, E. and Walton, R. L. and Ahmed, S. and others}, title = {{Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture}}, journal = {Nature genetics}, year = {2021}, doi = {10.1038/s41588-021-00785-3}, pmid = {33589841}, url = {https://doi.org/10.1038/s41588-021-00785-3} } @article{beecham2014-25188341, author = {Beecham, G. W. and Hamilton, K. and Naj, A. C. and Martin, E. R. and Huentelman, M. and Myers, A. J. and Corneveaux, J. J. and Hardy, J. and others}, title = {{Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias}}, journal = {PLoS genetics}, year = {2014}, doi = {10.1371/journal.pgen.1004606}, pmid = {25188341}, url = {https://doi.org/10.1371/journal.pgen.1004606} } @article{tijms2024-38195725, author = {Tijms, B. M. and Vromen, E. M. and Mjaavatten, O. and Holstege, H. and Reus, L. M. and van der Lee, S. and Wesenhagen, K. E. J. and Lorenzini, L. and others}, title = {{Cerebrospinal fluid proteomics in patients with Alzheimer's disease reveals five molecular subtypes with distinct genetic risk profiles}}, journal = {Nature aging}, year = {2024}, doi = {10.1038/s43587-023-00550-7}, pmid = {38195725}, url = {https://doi.org/10.1038/s43587-023-00550-7} } @article{skillback2014-24566866, author = {Skillbäck, T. and Rosén, C. and Asztely, F. and Mattsson, N. and Blennow, K. and Zetterberg, H.}, title = {{Diagnostic performance of cerebrospinal fluid total tau and phosphorylated tau in Creutzfeldt-Jakob disease: results from the Swedish Mortality Registry}}, journal = {JAMA neurology}, year = {2014}, doi = {10.1001/jamaneurol.2013.6455}, pmid = {24566866}, url = {https://doi.org/10.1001/jamaneurol.2013.6455} } @article{llibreguerra2019-31825500, author = {Llibre-Guerra, J. J. and Li, Y. and Schindler, S. E. and Gordon, B. A. and Fagan, A. M. and Morris, J. C. and Benzinger, T. L. S. and Hassenstab, J. and others}, title = {{Association of Longitudinal Changes in Cerebrospinal Fluid Total Tau and Phosphorylated Tau 181 and Brain Atrophy With Disease Progression in Patients With Alzheimer Disease}}, journal = {JAMA network open}, year = {2019}, doi = {10.1001/jamanetworkopen.2019.17126}, pmid = {31825500}, url = {https://doi.org/10.1001/jamanetworkopen.2019.17126} } @article{coysh2026-42441927, author = {Coysh, T. and Laban, R. and Veleva, E. and Heslegrave, A. J. and Darwent, L. and Holm-Mercer, L. and Mok, T. H. and Hart, M. S. and others}, title = {{Performance of Alzheimer Disease Plasma Biomarkers in Patients With Prion Diseases}}, journal = {Neurology}, year = {2026}, doi = {10.1212/wnl.0000000000214712}, pmid = {42441927}, url = {https://doi.org/10.1212/wnl.0000000000214712} } @article{cheung2025-40413804, author = {Cheung, Edmund Chi Lok and Adesuyan, Matthew and Szilcz, Máté and Ellett, Lisa M. Kalisch and Shah, Sonia H and Jani, Yogini Hariprasad and Hägg, Sara and Pratt, Nicole L. and others}, title = {{Antihypertensive drug classes and risk of incident dementia: a multinational population-based cohort study}}, journal = {Age and Ageing}, year = {2025}, doi = {10.1093/ageing/afaf121}, pmid = {40413804}, url = {https://doi.org/10.1093/ageing/afaf121} } @article{wardlaw2013-23867200, author = {Wardlaw, Joanna Marguerite and Smith, Eric Edward and Biessels, Geert Jan and Cordonnier, Charlotte and Fazekas, Franz and Frayne, Richard and Lindley, Richard I. and O'Brien, John Tiernan and others}, title = {{Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration}}, journal = {The Lancet Neurology}, year = {2013}, doi = {10.1016/s1474-4422(13)70124-8}, pmid = {23867200}, url = {https://doi.org/10.1016/s1474-4422(13)70124-8} } @article{page2021-33782057, author = {Page, Matthew James and McKenzie, Joanne E. and Bossuyt, Patrick M. and Boutron, Isabelle and Hoffmann, Tammy and Mulrow, Cynthia D. and Shamseer, Larissa and Tetzlaff, Jennifer and Akl, Elie A. and Brennan, Sue and Chou, Roger and Glanville, Julie and Grimshaw, Jeremy and Hróbjartsson, Asbjørn and Lalu, Manoj Mathew and Li, Tianjing and Loder, Elizabeth and Mayo‐Wilson, Evan and McDonald, Steve J and McGuinness, Luke A. and Stewart, Lesley A. and Thomas, James and Tricco, Andrea C. and Welch, Vivian Andrea and Whiting, Penny F. and Moher, David}, title = {{The PRISMA 2020 statement: an updated guideline for reporting systematic reviews}}, journal = {BMJ}, year = {2021}, doi = {10.1136/bmj.n71}, pmid = {33782057}, url = {https://doi.org/10.1136/bmj.n71} } @article{duering2023-37236211, author = {Duering, Marco and Biessels, Geert Jan and Brodtmann, Amy G. and Chen, Christopher and Cordonnier, Charlotte and de Leeuw, Frank‐Erik and Debette, Stéphanie and Frayne, Richard and Jouvent, Éric and Rost, Natalia S. and ter Telgte, Annemieke and Salman, Rustam Al‐Shahi and Backes, Walter H. and Bae, Hee‐Joon and Brown, Rosalind and Chabriat, Hugues and De Luca, Alberto and DeCarli, Charles S and Dewenter, Anna and Doubal, Fergus and Ewers, Michael and Field, Thalia Shoshana and Ganesh, Aravind and Greenberg, Steven Mark and Helmer, Karl G. and Hilal, Saima and Jochems, Angela C.C. and Jokinen, Hanna and Kuijf, Hugo J. and Lam, Bonnie Y. K. and Lebenberg, Jessica and MacIntosh, Bradley John and Maillard, Pauline and Mok, Vincent and Pantoni, Leonardo and Rudilosso, Salvatore and Satizábal, Claudia Liliana and Schirmer, Markus D. and Schmidt, Reinhold and Smith, Colin and Staals, Julie and Thrippleton, Michael J. and van Veluw, Susanne J. and Vemuri, Prashanthi and Wang, Yilong and Werring, David John and Zedde, Marialuisa and Akinyemi, Rufus and Del Brutto, Óscar H. and Markus, Hugh Stephen and Zhu, Yi‐Cheng and Smith, Eric Edward and Dichgans, Martin and Wardlaw, Joanna Marguerite}, title = {{Neuroimaging standards for research into small vessel disease—advances since 2013}}, journal = {The Lancet Neurology}, year = {2023}, doi = {10.1016/s1474-4422(23)00131-x}, pmid = {37236211}, url = {https://doi.org/10.1016/s1474-4422(23)00131-x} } @article{ashton2022-36456833, author = {Ashton, Nicholas James and Janelidze, Shorena and Mattsson, Niklas and Binette, Alexa Pichet and Strandberg, Olof T. and Brum, Wagner Scheeren and Karikari, Thomas K. and González‐Ortiz, Fernando and Di Molfetta, Guglielmo and Meda, Francisco J. and Jonaitis, Erin McMullen and Koscik, Rebecca L. and Cody, Karly Alex and Betthauser, Tobey J. and Li, Yan and Vanmechelen, Eugeen and Palmqvist, Sebastian and Stomrud, Erik and Bateman, Randall John and Zetterberg, Henrik and Johnson, Sterling C. and Blennow, Kaj and Hansson, Oskar}, title = {{Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer’s trial selection and disease monitoring}}, journal = {Nature Medicine}, year = {2022}, doi = {10.1038/s41591-022-02074-w}, pmid = {36456833}, url = {https://doi.org/10.1038/s41591-022-02074-w} } @article{milaaloma2022-35953717, author = {Milà-Alomà, M. and Ashton, N. J. and Shekari, M. and Salvadó, G. and Ortiz-Romero, P. and Montoliu-Gaya, L. and Benedet, A. L. and Karikari, T. K. and others}, title = {{Plasma p-tau231 and p-tau217 as state markers of amyloid-β pathology in preclinical Alzheimer's disease}}, journal = {Nature medicine}, year = {2022}, doi = {10.1038/s41591-022-01925-w}, pmid = {35953717}, url = {https://doi.org/10.1038/s41591-022-01925-w} } @article{janbek2026-42425116, author = {Janbek, J. and Laursen, T. M. and Jørgensen, K. and Jensen, M. M. and Eliasen, M. H. and Christensen, A. I. and Walsh, S. and Sommerlad, A. and Brayne, C. and Waldemar, G.}, title = {{Mapping dementia risk factors and their interactions in Denmark: a nationwide cohort study}}, journal = {The Lancet Public Health}, year = {2026}, doi = {10.1016/S2468-2667(26)00124-6}, pmid = {42425116}, url = {https://doi.org/10.1016/S2468-2667(26)00124-6} } @article{mastenbroek2025-40764485, author = {Mastenbroek, S. E. and Collij, L. E. and Vogel, J. W. and Caldera, S. and Serrano, G. E. and Adler, C. H. and Vargiu, C. M. and Palmqvist, S. and Barkhof, F. and Parchi, P. and others}, title = {{Two-step detection of Lewy body pathology via smell-function testing and CSF α-synuclein seed amplification}}, journal = {Nature Communications}, year = {2025}, doi = {10.1038/s41467-025-62458-7}, pmid = {40764485}, url = {https://doi.org/10.1038/s41467-025-62458-7} } @article{aye2025-39485581, author = {Aye, S. and Frisell, O. and Zetterberg, H. and Skillbäck, T. B. and Kern, S. and Eriksdotter, M. and Aho, E. and Xia, X. and Winblad, B. and Wimo, A. and Jönsson, L.}, title = {{Costs of Care in Relation to Alzheimer's Disease Severity in Sweden: A National Registry-Based Cohort Study}}, journal = {PharmacoEconomics}, year = {2025}, doi = {10.1007/s40273-024-01443-2}, pmid = {39485581}, url = {https://doi.org/10.1007/s40273-024-01443-2} } @article{sprecher2017-28679595, author = {Sprecher, K. E. and Koscik, R. L. and Carlsson, C. M. and Zetterberg, H. and Blennow, K. and Okonkwo, O. C. and Sager, M. A. and Asthana, S. and others}, title = {{Poor sleep is associated with CSF biomarkers of amyloid pathology in cognitively normal adults}}, journal = {Neurology}, year = {2017}, doi = {10.1212/wnl.0000000000004171}, pmid = {28679595}, url = {https://doi.org/10.1212/wnl.0000000000004171} } @article{collij2022-35292558, author = {Collij, L. E. and Salvadó, G. and Wottschel, V. and Mastenbroek, S. E. and Schoenmakers, P. and Heeman, F. and Aksman, L. and Wink, A. M. and others}, title = {{Spatial-Temporal Patterns of β-Amyloid Accumulation: A Subtype and Stage Inference Model Analysis}}, journal = {Neurology}, year = {2022}, doi = {10.1212/wnl.0000000000200148}, pmid = {35292558}, url = {https://doi.org/10.1212/wnl.0000000000200148} } @article{cicognola2023-37137722, author = {Cicognola, C. and Mattsson-Carlgren, N. and van Westen, D. and Zetterberg, H. and Blennow, K. and Palmqvist, S. and Ahmadi, K. and Strandberg, O. and others}, title = {{Associations of CSF PDGFRβ With Aging, Blood-Brain Barrier Damage, Neuroinflammation, and Alzheimer Disease Pathologic Changes}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000207358}, pmid = {37137722}, url = {https://doi.org/10.1212/wnl.0000000000207358} } @article{hofmann2024-39557867, author = {Hofmann, A. and Häsler, L. M. and Lambert, M. and Kaeser, S. A. and Gräber-Sultan, S. and Obermüller, U. and Kuder-Buletta, E. and la Fougere, C. and others}, title = {{Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer's disease}}, journal = {Nature communications}, year = {2024}, doi = {10.1038/s41467-024-52937-8}, pmid = {39557867}, url = {https://doi.org/10.1038/s41467-024-52937-8} } @article{kim2025-40042844, author = {Kim, S. A. and Shin, D. and Ham, H. and Kim, Y. and Gu, Y. and Kim, H. J. and Na, D. L. and Zetterberg, H. and others}, title = {{Physical Activity, Alzheimer Plasma Biomarkers, and Cognition}}, journal = {JAMA network open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.0096}, pmid = {40042844}, url = {https://doi.org/10.1001/jamanetworkopen.2025.0096} } @article{honig2024-38377442, author = {Hönig, M. and Altomare, D. and Caprioglio, C. and Collij, L. and Barkhof, F. and Van Berckel, B. and Scheltens, P. and Farrar, G. and others}, title = {{Association Between Years of Education and Amyloid Burden in Patients With Subjective Cognitive Decline, MCI, and Alzheimer Disease}}, journal = {Neurology}, year = {2024}, doi = {10.1212/wnl.0000000000208053}, pmid = {38377442}, url = {https://doi.org/10.1212/wnl.0000000000208053} } @article{ward2022-34933996, author = {Ward, D. D. and Ranson, J. M. and Wallace, L. M. K. and Llewellyn, D. J. and Rockwood, K.}, title = {{Frailty, lifestyle, genetics and dementia risk}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2022}, doi = {10.1136/jnnp-2021-327396}, pmid = {34933996}, url = {https://doi.org/10.1136/jnnp-2021-327396} } @article{shi2021-34588692, author = {Shi, Y. and Zhang, W. and Yang, Y. and Murzin, A. G. and Falcon, B. and Kotecha, A. and van Beers, M. and Tarutani, A. and others}, title = {{Structure-based classification of tauopathies}}, journal = {Nature}, year = {2021}, doi = {10.1038/s41586-021-03911-7}, pmid = {34588692}, url = {https://doi.org/10.1038/s41586-021-03911-7} } @article{singhmanoux2018-28943197, author = {Singh-Manoux, A. and Dugravot, A. and Shipley, M. and Brunner, E. J. and Elbaz, A. and Sabia, S. and Kivimaki, M.}, title = {{Obesity trajectories and risk of dementia: 28 years of follow-up in the Whitehall II Study}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2018}, doi = {10.1016/j.jalz.2017.06.2637}, pmid = {28943197}, url = {https://doi.org/10.1016/j.jalz.2017.06.2637} } @article{lee2016-27016429, author = {Lee, S. and Viqar, F. and Zimmerman, M. E. and Narkhede, A. and Tosto, G. and Benzinger, T. L. and Marcus, D. S. and Fagan, A. M. and others}, title = {{White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network}}, journal = {Annals of neurology}, year = {2016}, doi = {10.1002/ana.24647}, pmid = {27016429}, url = {https://doi.org/10.1002/ana.24647} } @article{vanmaurik2017-29049480, author = {van Maurik, I. S. and Zwan, M. D. and Tijms, B. M. and Bouwman, F. H. and Teunissen, C. E. and Scheltens, P. and Wattjes, M. P. and Barkhof, F. and others}, title = {{Interpreting Biomarker Results in Individual Patients With Mild Cognitive Impairment in the Alzheimer's Biomarkers in Daily Practice (ABIDE) Project}}, journal = {JAMA neurology}, year = {2017}, doi = {10.1001/jamaneurol.2017.2712}, pmid = {29049480}, url = {https://doi.org/10.1001/jamaneurol.2017.2712} } @article{clare2003-14583963, author = {Clare, L. and Woods, R. T. and Moniz Cook, E. D. and Orrell, M. and Spector, A.}, title = {{Cognitive rehabilitation and cognitive training for early-stage Alzheimer's disease and vascular dementia}}, journal = {The Cochrane database of systematic reviews}, year = {2003}, doi = {10.1002/14651858.cd003260}, pmid = {14583963}, url = {https://doi.org/10.1002/14651858.cd003260} } @article{russ2012-22798662, author = {Russ, T. C. and Batty, G. D. and Hearnshaw, G. F. and Fenton, C. and Starr, J. M.}, title = {{Geographical variation in dementia: systematic review with meta-analysis}}, journal = {International journal of epidemiology}, year = {2012}, doi = {10.1093/ije/dys103}, pmid = {22798662}, url = {https://doi.org/10.1093/ije/dys103} } @article{xavier2014-25116923, author = {Xavier, A. J. and d'Orsi, E. and de Oliveira, C. M. and Orrell, M. and Demakakos, P. and Biddulph, J. P. and Marmot, M. G.}, title = {{English Longitudinal Study of Aging: can Internet/E-mail use reduce cognitive decline?}}, journal = {The journals of gerontology. Series A, Biological sciences and medical sciences}, year = {2014}, doi = {10.1093/gerona/glu105}, pmid = {25116923}, url = {https://doi.org/10.1093/gerona/glu105} } @article{renton2011-21944779, author = {Renton, A. E. and Majounie, E. and Waite, A. and Simón-Sánchez, J. and Rollinson, S. and Gibbs, JR. and Schymick, J. C. and Laaksovirta, H. and others}, title = {{A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD}}, journal = {Neuron}, year = {2011}, doi = {10.1016/j.neuron.2011.09.010}, pmid = {21944779}, url = {https://doi.org/10.1016/j.neuron.2011.09.010} } @article{rohrer2016-27581216, author = {Rohrer, J. D. and Woollacott, I. O. and Dick, K. M. and Brotherhood, E. and Gordon, E. and Fellows, A. and Toombs, J. and Druyeh, R. and others}, title = {{Serum neurofilament light chain protein is a measure of disease intensity in frontotemporal dementia}}, journal = {Neurology}, year = {2016}, doi = {10.1212/wnl.0000000000003154}, pmid = {27581216}, url = {https://doi.org/10.1212/wnl.0000000000003154} } @article{yim2025-40829110, author = {Yim, Sohyun and Park, Seongbeom and Lim, Kyoungyoon and Kang, Heekyung and Shin, Daeun and Jo, Hyunjin and Jang, Hyemin and Weiner, Michael Walter and others}, title = {{Integrating MRI Volume and Plasma p-Tau217 for Amyloid Risk Stratification in Early-Stage Alzheimer Disease}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000213954}, pmid = {40829110}, url = {https://doi.org/10.1212/wnl.0000000000213954} } @article{mirza2025-40260680, author = {Mirza, Saira Saeed and Pasternak, Maurice M. and Paterson, Andrew D. and Rogaeva, Ekaterina A. and Tartaglia, Maria Carmela and Mitchell, Sara Berman and Black, Sandra E. and Freedman, Morris and others}, title = {{Disease-modifying effects of TMEM106B in genetic frontotemporal dementia: a longitudinal GENFI study}}, journal = {Brain}, year = {2025}, doi = {10.1093/brain/awaf019}, pmid = {40260680}, url = {https://doi.org/10.1093/brain/awaf019} } @article{kirsebom2025-40442871, author = {Kirsebom, Bjørn‐Eivind and González‐Ortiz, Fernando and Vigneswaran, Sinthujah and Bråthen, Geir and Skogseth, Ragnhild Eide and Gísladóttir, Berglind and Harrison, Peter and Jarholm, Jonas Alexander and others}, title = {{Repeated plasma p‐tau217 measurements to monitor clinical progression heterogeneity}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70319}, pmid = {40442871}, url = {https://doi.org/10.1002/alz.70319} } @article{dyer2025-40832852, author = {Dyer, Suzanne M and Kwok, Wing S and Suen, Jenni and Dawson, Rik and Kneale, Dylan and Sutcliffe, Katy and Seppala, Lotta J and Hill, Keith and others}, title = {{Interventions for preventing falls in older people in care facilities}}, journal = {Cochrane Database of Systematic Reviews}, year = {2025}, doi = {10.1002/14651858.cd016064}, pmid = {40832852}, url = {https://doi.org/10.1002/14651858.cd016064} } @article{study2020-32161412, author = {{the Dominantly Inherited Alzheimer Network} and Barthélemy, Nicolas R. and Li, Yan and Joseph‐Mathurin, Nelly and Gordon, Brian Andrew and Hassenstab, Jason J. and Benzinger, Tammie L.S. and Buckles, Virginia and Fagan, Anne M. and Perrin, Richard J. and Goate, Alison and Morris, John C. and Karch, Celeste M M. and Xiong, Chengjie and Allegri, Ricardo and Méndez, Patricio Chrem and Berman, Sarah B. and Ikeuchi, Takeshi and Mori, Hiroshi and Shimada, Hiroyuki and Shoji, Mikio and Suzuki, Kazushi and Noble, James McC. and Farlow, Martin Rhys and Chhatwal, Jasmeer P. and Graff‐Radford, Neill R. and Salloway, Stephen and Schofield, Peter R. and Masters, Colin Louis and Martins, Ralph Nigel and O’Connor, Antoinette and Fox, Nick C. and Levin, Johannes and Jucker, Mathias and Gabelle, Audrey and Lehmann, Sylvain and Sato, Chihiro and Bateman, Randall John and Bateman, Randall J. and McDade, Eric}, title = {{A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease}}, journal = {Nature Medicine}, year = {2020}, doi = {10.1038/s41591-020-0781-z}, pmid = {32161412}, url = {https://doi.org/10.1038/s41591-020-0781-z} } @article{gonzalez2025-40412418, author = {Gonzalez, L. and Rapaport, P. and Livingston, G. and Amador, S. and Adeleke, M. O. and Barber, J. A. and others}, title = {{Cost-utility analysis of the DREAMS START intervention for people living with dementia and their carers: a within-trial economic evaluation}}, journal = {The Lancet Healthy Longevity}, year = {2025}, doi = {10.1016/j.lanhl.2025.100708}, pmid = {40412418}, url = {https://doi.org/10.1016/j.lanhl.2025.100708} } @article{taddei2023-37812432, author = {Taddei, R. N. and Perbet, R. and Mate de Gerando, A. and Wiedmer, A. E. and Sanchez-Mico, M. and Connors Stewart, T. and Gaona, A. and Melloni, A. and others}, title = {{Tau Oligomer-Containing Synapse Elimination by Microglia and Astrocytes in Alzheimer Disease}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.3530}, pmid = {37812432}, url = {https://doi.org/10.1001/jamaneurol.2023.3530} } @article{fagan2021-34302786, author = {Fagan, A. M. and Henson, R. L. and Li, Y. and Boerwinkle, A. H. and Xiong, C. and Bateman, R. J. and Goate, A. and Ances, B. M. and others}, title = {{Comparison of CSF biomarkers in Down syndrome and autosomal dominant Alzheimer's disease: a cross-sectional study}}, journal = {The Lancet. Neurology}, year = {2021}, doi = {10.1016/s1474-4422(21)00139-3}, pmid = {34302786}, url = {https://doi.org/10.1016/s1474-4422(21)00139-3} } @article{kang2025-40343697, author = {Kang, S. H. and Lee, E. H. and Kim, Y. J. and Jang, H. and Shin, D. and Zetterberg, H. and Blennow, K. and Gonzalez-Ortiz, F. and others}, title = {{Cerebral Amyloid Angiopathy and Downstream Alzheimer Disease Plasma Biomarkers}}, journal = {JAMA network open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.8842}, pmid = {40343697}, url = {https://doi.org/10.1001/jamanetworkopen.2025.8842} } @article{sperling2012-22305802, author = {Sperling, R. and Salloway, S. and Brooks, D. J. and Tampieri, D. and Barakos, J. and Fox, N. C. and Raskind, M. and Sabbagh, M. and others}, title = {{Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis}}, journal = {The Lancet. Neurology}, year = {2012}, doi = {10.1016/s1474-4422(12)70015-7}, pmid = {22305802}, url = {https://doi.org/10.1016/s1474-4422(12)70015-7} } @article{chetelat2020-33098804, author = {Chételat, G. and Arbizu, J. and Barthel, H. and Garibotto, V. and Law, I. and Morbelli, S. and van de Giessen, E. and Agosta, F. and others}, title = {{Amyloid-PET and 18F-FDG-PET in the diagnostic investigation of Alzheimer's disease and other dementias}}, journal = {The Lancet. Neurology}, year = {2020}, doi = {10.1016/s1474-4422(20)30314-8}, pmid = {33098804}, url = {https://doi.org/10.1016/s1474-4422(20)30314-8} } @article{duits2014-24721526, author = {Duits, F. H. and Teunissen, C. E. and Bouwman, F. H. and Visser, P. J. and Mattsson, N. and Zetterberg, H. and Blennow, K. and Hansson, O. and others}, title = {{The cerebrospinal fluid "Alzheimer profile": easily said, but what does it mean?}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2014}, doi = {10.1016/j.jalz.2013.12.023}, pmid = {24721526}, url = {https://doi.org/10.1016/j.jalz.2013.12.023} } @article{weston2016-27733562, author = {Weston, P. S. and Nicholas, J. M. and Lehmann, M. and Ryan, N. S. and Liang, Y. and Macpherson, K. and Modat, M. and Rossor, M. N. and others}, title = {{Presymptomatic cortical thinning in familial Alzheimer disease: A longitudinal MRI study}}, journal = {Neurology}, year = {2016}, doi = {10.1212/wnl.0000000000003322}, pmid = {27733562}, url = {https://doi.org/10.1212/wnl.0000000000003322} } @article{selwood2007-17173977, author = {Selwood, A. and Johnston, K. and Katona, C. and Lyketsos, C. and Livingston, G.}, title = {{Systematic review of the effect of psychological interventions on family caregivers of people with dementia}}, journal = {Journal of affective disorders}, year = {2007}, doi = {10.1016/j.jad.2006.10.025}, pmid = {17173977}, url = {https://doi.org/10.1016/j.jad.2006.10.025} } @article{fox2004-15074306, author = {Fox, N. C. and Schott, J. M.}, title = {{Imaging cerebral atrophy: normal ageing to Alzheimer's disease}}, journal = {Lancet (London, England)}, year = {2004}, doi = {10.1016/s0140-6736(04)15441-x}, pmid = {15074306}, url = {https://doi.org/10.1016/s0140-6736(04)15441-x} } @article{lee2021-33947391, author = {Lee, S. and Zhou, J. and Wong, W. T. and Liu, T. and Wu, W. K. K. and Wong, I. C. K. and Zhang, Q. and Tse, G.}, title = {{Glycemic and lipid variability for predicting complications and mortality in diabetes mellitus using machine learning}}, journal = {BMC endocrine disorders}, year = {2021}, doi = {10.1186/s12902-021-00751-4}, pmid = {33947391}, url = {https://doi.org/10.1186/s12902-021-00751-4} } @article{rohrer2015-25662776, author = {Rohrer, J. D. and Nicholas, J. M. and Cash, D. M. and van Swieten, J. and Dopper, E. and Jiskoot, L. and van Minkelen, R. and Rombouts, S. A. and others}, title = {{Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis}}, journal = {The Lancet. Neurology}, year = {2015}, doi = {10.1016/s1474-4422(14)70324-2}, pmid = {25662776}, url = {https://doi.org/10.1016/s1474-4422(14)70324-2} } @article{molinuevo2018-30488277, author = {Molinuevo, J. L. and Ayton, S. and Batrla, R. and Bednar, M. M. and Bittner, T. and Cummings, J. and Fagan, A. M. and Hampel, H. and others}, title = {{Current state of Alzheimer's fluid biomarkers}}, journal = {Acta neuropathologica}, year = {2018}, doi = {10.1007/s00401-018-1932-x}, pmid = {30488277}, url = {https://doi.org/10.1007/s00401-018-1932-x} } @article{garciaalonso2022-35794482, author = {Garcia-Alonso, L. and Lorenzi, V. and Mazzeo, C. I. and Alves-Lopes, J. P. and Roberts, K. and Sancho-Serra, C. and Engelbert, J. and Marečková, M. and others}, title = {{Single-cell roadmap of human gonadal development}}, journal = {Nature}, year = {2022}, doi = {10.1038/s41586-022-04918-4}, pmid = {35794482}, url = {https://doi.org/10.1038/s41586-022-04918-4} } @article{cooperknock2012-22366792, author = {Cooper-Knock, J. and Hewitt, C. and Highley, JR. and Brockington, A. and Milano, A. and Man, S. and Martindale, J. and Hartley, J. and others}, title = {{Clinico-pathological features in amyotrophic lateral sclerosis with expansions in C9ORF72}}, journal = {Brain : a journal of neurology}, year = {2012}, doi = {10.1093/brain/awr365}, pmid = {22366792}, url = {https://doi.org/10.1093/brain/awr365} } @article{sittichokkananon2025-40181791, author = {Sittichokkananon, Arisa and Garfield, Victoria and Chiesa, Scott T.}, title = {{Genetic and Lifestyle Risks for Coronary Artery Disease and Long-Term Risk of Incident Dementia Subtypes}}, journal = {Circulation}, year = {2025}, doi = {10.1161/circulationaha.124.070632}, pmid = {40181791}, url = {https://doi.org/10.1161/circulationaha.124.070632} } @article{deboer2025-39951678, author = {de Boer, Liset and Poos, Jackie M. and van den Berg, Esther and De Houwer, Julie F. H. and Swartenbroekx, Tine and Dopper, Elise G.P. and Boesjes, Pam and Tahboun, Najlae and others}, title = {{Montreal Cognitive Assessment vs the Mini-Mental State Examination as a Screening Tool for Patients With Genetic Frontotemporal Dementia}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000213401}, pmid = {39951678}, url = {https://doi.org/10.1212/wnl.0000000000213401} } @article{winblad2016-26987701, author = {Winblad, Bengt G. and Amouyel, Philippe and Andrieu, Sandrine and Ballard, Clive G. and Brayne, Carol and Brodaty, Henry and Cedazo-Mínguez, Ángel and Dubois, Bruno and Edvardsson, David and Feldman, Howard and Fratiglioni, Laura and Frisoni, Giovanni Battista and Gauthier, Serge G. and Georges, Jean and Graff, Caroline and Iqbal, Khalid and Jessen, Frank and Johansson, Gunilla and Jönsson, Linus and Kivipelto, Miia and Knapp, Martin Richard John and Mangialasche, Francesca and Melis, René J. F. and Nordberg, Agneta K. and Rikkert, Marcel G. M. Olde and Qiu, Chengxuan and Sakmar, Thomas P. and Scheltens, Philip and Schneider, Lon S. S. and Sperling, Reisa Anne and Tjernberg, Lars O. and Waldemar, Gunhild and Wimo, Anders and Zetterberg, Henrik}, title = {{Defeating Alzheimer's disease and other dementias: a priority for European science and society}}, journal = {The Lancet Neurology}, year = {2016}, doi = {10.1016/s1474-4422(16)00062-4}, pmid = {26987701}, url = {https://doi.org/10.1016/s1474-4422(16)00062-4} } @article{demnitzking2026-42328805, author = {Demnitz-King, Harriet and Cooper, Claudia and Poppe, Michaela and Budgett, Jessica and Alberts, Sweedal and Duffy, Larisa and Adeleke, Mariam and Barber, Julie and others}, title = {{Cost utility and cost-effectiveness of the APPLE-Tree programme: Active Prevention in People at risk of dementia through Lifestyle, bEhaviour change and Technology to build REsiliEnce: economic evaluation embedded within a randomised controlled trial}}, journal = {Age and ageing}, year = {2026}, doi = {10.1093/ageing/afag176}, pmid = {42328805}, url = {https://doi.org/10.1093/ageing/afag176} } @article{verdi2023-37127353, author = {Verdi, S. and Kia, S. M. and Yong, K. X. X. and Tosun, D. and Schott, J. M. and Marquand, A. F. and Cole, J. H.}, title = {{Revealing Individual Neuroanatomical Heterogeneity in Alzheimer Disease Using Neuroanatomical Normative Modeling}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000207298}, pmid = {37127353}, url = {https://doi.org/10.1212/wnl.0000000000207298} } @article{reiman2020-32015339, author = {Reiman, E. M. and Arboleda-Velasquez, J. F. and Quiroz, Y. T. and Huentelman, M. J. and Beach, T. G. and Caselli, R. J. and Chen, Y. and Su, Y. and others}, title = {{Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study}}, journal = {Nature communications}, year = {2020}, doi = {10.1038/s41467-019-14279-8}, pmid = {32015339}, url = {https://doi.org/10.1038/s41467-019-14279-8} } @article{shah2016-27751558, author = {Shah, H. and Albanese, E. and Duggan, C. and Rudan, I. and Langa, K. M. and Carrillo, M. C. and Chan, K. Y. and Joanette, Y. and others}, title = {{Research priorities to reduce the global burden of dementia by 2025}}, journal = {The Lancet. Neurology}, year = {2016}, doi = {10.1016/s1474-4422(16)30235-6}, pmid = {27751558}, url = {https://doi.org/10.1016/s1474-4422(16)30235-6} } @article{dean2017-27842175, author = {Dean, D. C. and Hurley, S. A. and Kecskemeti, SR. and O'Grady, J. P. and Canda, C. and Davenport-Sis, N. J. and Carlsson, C. M. and Zetterberg, H. and others}, title = {{Association of Amyloid Pathology With Myelin Alteration in Preclinical Alzheimer Disease}}, journal = {JAMA neurology}, year = {2017}, doi = {10.1001/jamaneurol.2016.3232}, pmid = {27842175}, url = {https://doi.org/10.1001/jamaneurol.2016.3232} } @article{kaffashian2013-23547265, author = {Kaffashian, S. and Dugravot, A. and Elbaz, A. and Shipley, M. J. and Sabia, S. and Kivimäki, M. and Singh-Manoux, A.}, title = {{Predicting cognitive decline: a dementia risk score vs. the Framingham vascular risk scores}}, journal = {Neurology}, year = {2013}, doi = {10.1212/wnl.0b013e31828ab370}, pmid = {23547265}, url = {https://doi.org/10.1212/wnl.0b013e31828ab370} } @article{mckhann2011-21514250, author = {McKhann, G. M. and Knopman, D. S. and Chertkow, H. and Hyman, B. T. and Jack, C. R. and Kawas, C. H. and Klunk, W. E. and Koroshetz, W. J. and others}, title = {{The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2011}, doi = {10.1016/j.jalz.2011.03.005}, pmid = {21514250}, url = {https://doi.org/10.1016/j.jalz.2011.03.005} } @article{petersen2001-11735772, author = {Petersen, R. C. and Doody, R. and Kurz, A. and Mohs, R. C. and Morris, J. C. and Rabins, P. V. and Ritchie, K. and Rossor, M. and others}, title = {{Current concepts in mild cognitive impairment}}, journal = {Archives of neurology}, year = {2001}, doi = {10.1001/archneur.58.12.1985}, pmid = {11735772}, url = {https://doi.org/10.1001/archneur.58.12.1985} } @article{dubois2010-20934914, author = {Dubois, B. and Feldman, H. H. and Jacova, C. and Cummings, J. L. and Dekosky, S. T. and Barberger-Gateau, P. and Delacourte, A. and Frisoni, G. and others}, title = {{Revising the definition of Alzheimer's disease: a new lexicon}}, journal = {The Lancet. Neurology}, year = {2010}, doi = {10.1016/s1474-4422(10)70223-4}, pmid = {20934914}, url = {https://doi.org/10.1016/s1474-4422(10)70223-4} } @article{dubois2024-39483064, author = {Dubois, B. and Villain, N. and Schneider, L. and Fox, N. and Campbell, N. and Galasko, D. and Kivipelto, M. and Jessen, F. and others}, title = {{Alzheimer Disease as a Clinical-Biological Construct-An International Working Group Recommendation}}, journal = {JAMA neurology}, year = {2024}, doi = {10.1001/jamaneurol.2024.3770}, pmid = {39483064}, url = {https://doi.org/10.1001/jamaneurol.2024.3770} } @article{garciacasal2017-26806365, author = {García-Casal, J. A. and Loizeau, A. and Csipke, E. and Franco-Martín, M. and Perea-Bartolomé, M. V. and Orrell, M.}, title = {{Computer-based cognitive interventions for people living with dementia: a systematic literature review and meta-analysis}}, journal = {Aging \& mental health}, year = {2017}, doi = {10.1080/13607863.2015.1132677}, pmid = {26806365}, url = {https://doi.org/10.1080/13607863.2015.1132677} } @article{suemoto2023-36326095, author = {Suemoto, C. K. and Mukadam, N. and Brucki, S. M. D. and Caramelli, P. and Nitrini, R. and Laks, J. and Livingston, G. and Ferri, C. P.}, title = {{Risk factors for dementia in Brazil: Differences by region and race}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2023}, doi = {10.1002/alz.12820}, pmid = {36326095}, url = {https://doi.org/10.1002/alz.12820} } @article{johnson2010-21145000, author = {Johnson, J. O. and Mandrioli, J. and Benatar, M. and Abramzon, Y. and Van Deerlin, V. M. and Trojanowski, J. Q. and Gibbs, JR. and Brunetti, M. and others}, title = {{Exome sequencing reveals VCP mutations as a cause of familial ALS}}, journal = {Neuron}, year = {2010}, doi = {10.1016/j.neuron.2010.11.036}, pmid = {21145000}, url = {https://doi.org/10.1016/j.neuron.2010.11.036} } @article{harper2016-26936938, author = {Harper, L. and Fumagalli, G. G. and Barkhof, F. and Scheltens, P. and O'Brien, J. T. and Bouwman, F. and Burton, E. J. and Rohrer, J. D. and others}, title = {{MRI visual rating scales in the diagnosis of dementia: evaluation in 184 post-mortem confirmed cases}}, journal = {Brain : a journal of neurology}, year = {2016}, doi = {10.1093/brain/aww005}, pmid = {26936938}, url = {https://doi.org/10.1093/brain/aww005} } @article{foltynie2024-38245250, author = {Foltynie, T. and Bruno, V. and Fox, S. and Kühn, A. A. and Lindop, F. and Lees, A. J.}, title = {{Medical, surgical, and physical treatments for Parkinson's disease}}, journal = {Lancet (London, England)}, year = {2024}, doi = {10.1016/s0140-6736(23)01429-0}, pmid = {38245250}, url = {https://doi.org/10.1016/s0140-6736(23)01429-0} } @article{verhaar2021-35173707, author = {Verhaar, B. J. H. and Hendriksen, H. M. A. and de Leeuw, F. A. and Doorduijn, A. S. and van Leeuwenstijn, M. and Teunissen, C. E. and Barkhof, F. and Scheltens, P. and others}, title = {{Gut Microbiota Composition Is Related to AD Pathology}}, journal = {Frontiers in immunology}, year = {2021}, doi = {10.3389/fimmu.2021.794519}, pmid = {35173707}, url = {https://doi.org/10.3389/fimmu.2021.794519} } @article{young2021-34158384, author = {Young, A. L. and Bocchetta, M. and Russell, L. L. and Convery, R. S. and Peakman, G. and Todd, E. and Cash, D. M. and Greaves, C. V. and others}, title = {{Characterizing the Clinical Features and Atrophy Patterns of MAPT-Related Frontotemporal Dementia With Disease Progression Modeling}}, journal = {Neurology}, year = {2021}, doi = {10.1212/wnl.0000000000012410}, pmid = {34158384}, url = {https://doi.org/10.1212/wnl.0000000000012410} } @article{crutch2017-28259709, author = {Crutch, S. J. and Schott, J. M. and Rabinovici, G. D. and Murray, M. and Snowden, J. S. and van der Flier, W. M. and Dickerson, B. C. and Vandenberghe, R. and others}, title = {{Consensus classification of posterior cortical atrophy}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2017}, doi = {10.1016/j.jalz.2017.01.014}, pmid = {28259709}, url = {https://doi.org/10.1016/j.jalz.2017.01.014} } @article{morgan2019-31047856, author = {Morgan, A. R. and Touchard, S. and Leckey, C. and O'Hagan, C. and Nevado-Holgado, A. J. and {NIMA Consortium} and Barkhof, F. and Bertram, L. and others}, title = {{Inflammatory biomarkers in Alzheimer's disease plasma}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2019}, doi = {10.1016/j.jalz.2019.03.007}, pmid = {31047856}, url = {https://doi.org/10.1016/j.jalz.2019.03.007} } @article{li2024-38478804, author = {Li, G. and Iliff, J. and Shofer, J. and Mayer, C. L. and Meabon, J. and Cook, D. and Pagulayan, K. F. and Raskind, M. A. and others}, title = {{CSF β-Amyloid and Tau Biomarker Changes in Veterans With Mild Traumatic Brain Injury}}, journal = {Neurology}, year = {2024}, doi = {10.1212/wnl.0000000000209197}, pmid = {38478804}, url = {https://doi.org/10.1212/wnl.0000000000209197} } @article{vanderlee2019-31131421, author = {van der Lee, S. J. and Conway, O. J. and Jansen, I. and Carrasquillo, M. M. and Kleineidam, L. and van den Akker, E. and Hernández, I. and van Eijk, K. R. and others}, title = {{A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity}}, journal = {Acta neuropathologica}, year = {2019}, doi = {10.1007/s00401-019-02026-8}, pmid = {31131421}, url = {https://doi.org/10.1007/s00401-019-02026-8} } @article{lindbohm2022-34338426, author = {Lindbohm, J. V. and Mars, N. and Walker, K. A. and Singh-Manoux, A. and Livingston, G. and Brunner, E. J. and Sipilä, P. N. and Saksela, K. and others}, title = {{Plasma proteins, cognitive decline, and 20-year risk of dementia in the Whitehall II and Atherosclerosis Risk in Communities studies}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2022}, doi = {10.1002/alz.12419}, pmid = {34338426}, url = {https://doi.org/10.1002/alz.12419} } @article{aarsland2025-41407852, author = {Aarsland, Dag and Sunde, Anita Lenora and Tovar, Diego and Leuzy, Antoine and Fladby, Tormod and Zetterberg, Henrik and Blennow, Kaj and Tan, Kübra and others}, title = {{Prevalence of Alzheimer’s disease pathology in the community}}, journal = {Nature}, year = {2025}, doi = {10.1038/s41586-025-09841-y}, pmid = {41407852}, url = {https://doi.org/10.1038/s41586-025-09841-y} } @article{gong2025-40092369, author = {Gong, Jessica and Williams, Dylan M. and Scholes, Shaun and Assaad, Sarah and Bu, Feifei and Hayat, Shabina A. and Zaninotto, Paola and Steptoe, Andrew}, title = {{Unraveling the role of proteins in dementia: insights from two UK cohorts with causal evidence}}, journal = {Brain Communications}, year = {2025}, doi = {10.1093/braincomms/fcaf097}, pmid = {40092369}, url = {https://doi.org/10.1093/braincomms/fcaf097} } @article{albert2011-21514249, author = {Albert, Marilyn S. and DeKosky, Steven T. and Dickson, Dennis W. and Dubois, Bruno and Feldman, Howard and Fox, Nick C. and Gamst, Anthony C. and Holtzman, David M. and others}, title = {{The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease}}, journal = {Alzheimer s \& Dementia}, year = {2011}, doi = {10.1016/j.jalz.2011.03.008}, pmid = {21514249}, url = {https://doi.org/10.1016/j.jalz.2011.03.008} } @article{selkoe2016-27025652, author = {Selkoe, Dennis J. and Hardy, John}, title = {{The amyloid hypothesis of Alzheimer's disease at 25 years}}, journal = {EMBO Molecular Medicine}, year = {2016}, doi = {10.15252/emmm.201606210}, pmid = {27025652}, url = {https://doi.org/10.15252/emmm.201606210} } @article{armstrong2013-23359374, author = {Armstrong, Melissa J. and Litvan, Irene and Lang, Anthony E. and Bak, Thomas H. and Bhatia, Kailash P. and Borroni, Barbara and Boxer, Adam L. and Dickson, Dennis W. and Grossman, Murray and Hallett, Mark and Josephs, Keith A. and KERTESZ, ANDREW E. and Lee, Suzee E. and Miller, Bruce L. and Reich, Stephen G. and Riley, David E. and TOLOSA, EDUARDO S. and Tröster, Alexander I. and Vidailhet, Marie and Weiner, William J.}, title = {{Criteria for the diagnosis of corticobasal degeneration}}, journal = {Neurology}, year = {2013}, doi = {10.1212/wnl.0b013e31827f0fd1}, pmid = {23359374}, url = {https://doi.org/10.1212/wnl.0b013e31827f0fd1} } @article{palmqvist2017-29089479, author = {Palmqvist, Sebastian and Schöll, Michael and Strandberg, Olof T. and Mattsson, Niklas and Stomrud, Erik and Zetterberg, Henrik and Blennow, Kaj and Landau, Susan M. and Jagust, William J. and Hansson, Oskar}, title = {{Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity}}, journal = {Nature Communications}, year = {2017}, doi = {10.1038/s41467-017-01150-x}, pmid = {29089479}, url = {https://doi.org/10.1038/s41467-017-01150-x} } @article{wischik2026-41570392, author = {Wischik, C. M. and Stefanacci, R. and Bentham, P. and Gauthier, S. and Zetterberg, H. and Wilcock, G. K. and Froelich, L. and Burns, A. and MacSweeney, E. and Ballard, C. and others}, title = {{Clinical, imaging and blood biomarker outcomes in a Phase 3 clinical trial of tau aggregation inhibitor hydromethylthionine mesylate in mild cognitive impairment and mild to moderate dementia due to Alzheimer's disease}}, journal = {The Journal of Prevention of Alzheimer's Disease}, year = {2026}, doi = {10.1016/j.tjpad.2026.100480}, pmid = {41570392}, url = {https://doi.org/10.1016/j.tjpad.2026.100480} } @article{frank2025-41412145, author = {Frank, P. and Singh-Manoux, A. and Pentti, J. and Batty, G. D. and Sommerlad, A. and Steptoe, A. and others}, title = {{Specific midlife depressive symptoms and long-term dementia risk: a 23-year UK prospective cohort study}}, journal = {Lancet Psychiatry}, year = {2025}, doi = {10.1016/S2215-0366(25)00331-1}, pmid = {41412145}, url = {https://doi.org/10.1016/S2215-0366(25)00331-1} } @article{janelidze2016-27042676, author = {Janelidze, S. and Zetterberg, H. and Mattsson, N. and Palmqvist, S. and Vanderstichele, H. and Lindberg, O. and van Westen, D. and Stomrud, E. and others}, title = {{CSF Aβ42/Aβ40 and Aβ42/Aβ38 ratios: better diagnostic markers of Alzheimer disease}}, journal = {Annals of clinical and translational neurology}, year = {2016}, doi = {10.1002/acn3.274}, pmid = {27042676}, url = {https://doi.org/10.1002/acn3.274} } @article{grothe2021-34266917, author = {Grothe, M. J. and Moscoso, A. and Ashton, N. J. and Karikari, T. K. and Lantero-Rodriguez, J. and Snellman, A. and Zetterberg, H. and Blennow, K. and others}, title = {{Associations of Fully Automated CSF and Novel Plasma Biomarkers With Alzheimer Disease Neuropathology at Autopsy}}, journal = {Neurology}, year = {2021}, doi = {10.1212/wnl.0000000000012513}, pmid = {34266917}, url = {https://doi.org/10.1212/wnl.0000000000012513} } @article{hazan2024-39353147, author = {Hazan, J. and Liu, K. Y. and Costello, H. and Isaacs, J. D. and Thambisetty, M. and Howard, R.}, title = {{Challenges in a Biological Definition of Alzheimer Disease}}, journal = {Neurology}, year = {2024}, doi = {10.1212/wnl.0000000000209884}, pmid = {39353147}, url = {https://doi.org/10.1212/wnl.0000000000209884} } @article{li2023-38019518, author = {Li, X. and Yucel, R. and Clervius, H. and Kamalakar, K. and Zetterberg, H. and Blennow, K. and Zhang, J. and Adimora, A. and others}, title = {{Plasma Biomarkers of Alzheimer Disease in Women With and Without HIV}}, journal = {JAMA network open}, year = {2023}, doi = {10.1001/jamanetworkopen.2023.44194}, pmid = {38019518}, url = {https://doi.org/10.1001/jamanetworkopen.2023.44194} } @article{ballard2015-25523285, author = {Ballard, C. and Thomas, A. and Gerry, S. and Yu, L. M. and Aarsland, D. and Merritt, C. and Corbett, A. and Davison, C. and others}, title = {{A double-blind randomized placebo-controlled withdrawal trial comparing memantine and antipsychotics for the long-term treatment of function and neuropsychiatric symptoms in people with Alzheimer's disease (MAIN-AD)}}, journal = {Journal of the American Medical Directors Association}, year = {2015}, doi = {10.1016/j.jamda.2014.11.002}, pmid = {25523285}, url = {https://doi.org/10.1016/j.jamda.2014.11.002} } @article{vanderlee2018-29316447, author = {van der Lee, S. J. and Teunissen, C. E. and Pool, R. and Shipley, M. J. and Teumer, A. and Chouraki, V. and Melo van Lent, D. and Tynkkynen, J. and others}, title = {{Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2018}, doi = {10.1016/j.jalz.2017.11.012}, pmid = {29316447}, url = {https://doi.org/10.1016/j.jalz.2017.11.012} } @article{kloppel2008-18202106, author = {Klöppel, S. and Stonnington, C. M. and Chu, C. and Draganski, B. and Scahill, R. I. and Rohrer, J. D. and Fox, N. C. and Jack, C. R. and others}, title = {{Automatic classification of MR scans in Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2008}, doi = {10.1093/brain/awm319}, pmid = {18202106}, url = {https://doi.org/10.1093/brain/awm319} } @article{fagan2014-24598588, author = {Fagan, A. M. and Xiong, C. and Jasielec, M. S. and Bateman, R. J. and Goate, A. M. and Benzinger, T. L. and Ghetti, B. and Martins, R. N. and others}, title = {{Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease}}, journal = {Science translational medicine}, year = {2014}, doi = {10.1126/scitranslmed.3007901}, pmid = {24598588}, url = {https://doi.org/10.1126/scitranslmed.3007901} } @article{thomas2014-25069482, author = {Thomas, J. B. and Brier, M. R. and Bateman, R. J. and Snyder, A. Z. and Benzinger, T. L. and Xiong, C. and Raichle, M. and Holtzman, D. M. and others}, title = {{Functional connectivity in autosomal dominant and late-onset Alzheimer disease}}, journal = {JAMA neurology}, year = {2014}, doi = {10.1001/jamaneurol.2014.1654}, pmid = {25069482}, url = {https://doi.org/10.1001/jamaneurol.2014.1654} } @article{monizcook2008-18297476, author = {Moniz-Cook, E. and Vernooij-Dassen, M. and Woods, R. and Verhey, F. and Chattat, R. and De Vugt, M. and Mountain, G. and O'Connell, M. and others}, title = {{A European consensus on outcome measures for psychosocial intervention research in dementia care}}, journal = {Aging \& mental health}, year = {2008}, doi = {10.1080/13607860801919850}, pmid = {18297476}, url = {https://doi.org/10.1080/13607860801919850} } @article{cooper2016-27473843, author = {Cooper, S. A. and Ademola, T. and Caslake, M. and Douglas, E. and Evans, J. and Greenlaw, N. and Haig, C. and Hassiotis, A. and others}, title = {{Towards onset prevention of cognition decline in adults with Down syndrome (The TOP-COG study): A pilot randomised controlled trial}}, journal = {Trials}, year = {2016}, doi = {10.1186/s13063-016-1370-9}, pmid = {27473843}, url = {https://doi.org/10.1186/s13063-016-1370-9} } @article{vanmaurik2019-31526625, author = {van Maurik, I. S. and Vos, S. J. and Bos, I. and Bouwman, F. H. and Teunissen, C. E. and Scheltens, P. and Barkhof, F. and Frolich, L. and others}, title = {{Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study}}, journal = {The Lancet. Neurology}, year = {2019}, doi = {10.1016/s1474-4422(19)30283-2}, pmid = {31526625}, url = {https://doi.org/10.1016/s1474-4422(19)30283-2} } @article{suarezcalvet2016-26941262, author = {Suárez-Calvet, M. and Kleinberger, G. and MÁ, Araque Caballero and Brendel, M. and Rominger, A. and Alcolea, D. and Fortea, J. and Lleó, A. and others}, title = {{sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers}}, journal = {EMBO molecular medicine}, year = {2016}, doi = {10.15252/emmm.201506123}, pmid = {26941262}, url = {https://doi.org/10.15252/emmm.201506123} } @article{heslegrave2016-26754172, author = {Heslegrave, A. and Heywood, W. and Paterson, R. and Magdalinou, N. and Svensson, J. and Johansson, P. and Öhrfelt, A. and Blennow, K. and others}, title = {{Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer's disease}}, journal = {Molecular neurodegeneration}, year = {2016}, doi = {10.1186/s13024-016-0071-x}, pmid = {26754172}, url = {https://doi.org/10.1186/s13024-016-0071-x} } @article{pereira2022-37118533, author = {Pereira, J. B. and Janelidze, S. and Strandberg, O. and Whelan, C. D. and Zetterberg, H. and Blennow, K. and Palmqvist, S. and Stomrud, E. and others}, title = {{Microglial activation protects against accumulation of tau aggregates in nondemented individuals with underlying Alzheimer's disease pathology}}, journal = {Nature aging}, year = {2022}, doi = {10.1038/s43587-022-00310-z}, pmid = {37118533}, url = {https://doi.org/10.1038/s43587-022-00310-z} } @article{clark2018-29523644, author = {Clark, L. R. and Berman, S. E. and Norton, D. and Koscik, R. L. and Jonaitis, E. and Blennow, K. and Bendlin, B. B. and Asthana, S. and others}, title = {{Age-accelerated cognitive decline in asymptomatic adults with CSF β-amyloid}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000005291}, pmid = {29523644}, url = {https://doi.org/10.1212/wnl.0000000000005291} } @article{theodorou2025-38869035, author = {Theodorou, A. and Tsantzali, I. and Stefanou, M. I. and Sacco, S. and Katsanos, A. H. and Shoamanesh, A. and Karapanayiotides, T. and Koutroulou, I. and others}, title = {{CSF and plasma biomarkers in cerebral amyloid angiopathy: A single-center study and a systematic review/meta-analysis}}, journal = {European stroke journal}, year = {2025}, doi = {10.1177/23969873241260538}, pmid = {38869035}, url = {https://doi.org/10.1177/23969873241260538} } @article{gonzalezortiz2023-37232524, author = {Gonzalez-Ortiz, F. and Dias, A. and Turton, M. and Magalhães, R. and Kac, P. R. and Correia, M. and Harrison, P. and Zetterberg, H. and others}, title = {{Preanalytical stability of plasma/serum brain-derived tau}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2023}, doi = {10.1002/alz.13156}, pmid = {37232524}, url = {https://doi.org/10.1002/alz.13156} } @article{lopezmartos2025-41105892, author = {López-Martos, D. and Suárez-Calvet, M. and Milà-Alomà, M. and Gispert, J. D. and Salvadó, G. and Brugulat-Serrat, A. and Shekari, M. and Minguillon, C. and others}, title = {{Longitudinal Associations of Multimodal Core 1 Alzheimer Disease Biomarkers With Cognition in Aging and Preclinical Alzheimer Disease}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000214308}, pmid = {41105892}, url = {https://doi.org/10.1212/wnl.0000000000214308} } @article{whitfield2025-41267582, author = {Whitfield, Elenyd M and Cooper, Claudia and Demnitz‐King, Harriet and Zabihi, Sedigheh and Barber, Julie and Adeleke, Mariam Olaide and Morse, Rachel M. and Ahmed, A Karim and others}, title = {{Process evaluation of APPLE-Tree (active prevention in people at risk of dementia through lifestyle behaviour change and technology to build resilience): dementia prevention study focused on health and lifestyle changes}}, journal = {BJPsych Open}, year = {2025}, doi = {10.1192/bjo.2025.10874}, pmid = {41267582}, url = {https://doi.org/10.1192/bjo.2025.10874} } @article{amador2025-40116618, author = {Amador, Sarah and Livingston, Gill and Adeleke, Mariam Olaide and Barber, Julie and Webster, Lucy Anne and Yuan, Hang and Banerjee, Sube and Bhojwani, Ankita and others}, title = {{Process evaluation in a randomised controlled trial of DREAMS-START (dementia related manual for sleep; strategies for relatives) for sleep disturbance in people with dementia and their carers}}, journal = {Age and Ageing}, year = {2025}, doi = {10.1093/ageing/afaf053}, pmid = {40116618}, url = {https://doi.org/10.1093/ageing/afaf053} } @article{sharif2025-40279515, author = {Sharif, Sergio Fernandez and Guan, Dylan X. and Bodnar, Tamara S. and Joseph, Jeffrey T. and Zetterberg, Henrik and Smith, Eric Edward and Ismail, Zahinoor}, title = {{Neuropsychiatric symptoms and progression to pathologically confirmed Alzheimer’s disease}}, journal = {Brain}, year = {2025}, doi = {10.1093/brain/awaf156}, pmid = {40279515}, url = {https://doi.org/10.1093/brain/awaf156} } @article{hansson2022-35908251, author = {Hansson, Oskar and Edelmayer, Rebecca M. and Boxer, Adam L. and Carrillo, María C. and Mielke, Michelle M. and Rabinovici, Gil D. and Salloway, Stephen and Sperling, Reisa Anne and Zetterberg, Henrik and Teunissen, Charlotte Elisabeth}, title = {{The Alzheimer's Association appropriate use recommendations for blood biomarkers in Alzheimer's disease}}, journal = {Alzheimer s \& Dementia}, year = {2022}, doi = {10.1002/alz.12756}, pmid = {35908251}, url = {https://doi.org/10.1002/alz.12756} } @article{oeckl2023-37052206, author = {Oeckl, P. and Bluma, M. and Bucci, M. and Halbgebauer, S. and Chiotis, K. and Sandebring-Matton, A. and Ashton, N. J. and Molfetta, G. D. and others}, title = {{Blood β-synuclein is related to amyloid PET positivity in memory clinic patients}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2023}, doi = {10.1002/alz.13046}, pmid = {37052206}, url = {https://doi.org/10.1002/alz.13046} } @article{hollingworth2012-22005930, author = {Hollingworth, P. and Sweet, R. and Sims, R. and Harold, D. and Russo, G. and Abraham, R. and Stretton, A. and Jones, N. and others}, title = {{Genome-wide association study of Alzheimer's disease with psychotic symptoms}}, journal = {Molecular psychiatry}, year = {2012}, doi = {10.1038/mp.2011.125}, pmid = {22005930}, url = {https://doi.org/10.1038/mp.2011.125} } @article{cunningham2019-31082921, author = {Cunningham, E. L. and McGuinness, B. and McAuley, D. F. and Toombs, J. and Mawhinney, T. and O'Brien, S. and Beverland, D. and Schott, J. M. and others}, title = {{CSF Beta-amyloid 1-42 Concentration Predicts Delirium Following Elective Arthroplasty Surgery in an Observational Cohort Study}}, journal = {Annals of surgery}, year = {2019}, doi = {10.1097/sla.0000000000002684}, pmid = {31082921}, url = {https://doi.org/10.1097/sla.0000000000002684} } @article{ko2018-29946685, author = {Ko, F. and Muthy, Z. A. and Gallacher, J. and Sudlow, C. and Rees, G. and Yang, Q. and Keane, P. A. and Petzold, A. and others}, title = {{Association of Retinal Nerve Fiber Layer Thinning With Current and Future Cognitive Decline: A Study Using Optical Coherence Tomography}}, journal = {JAMA neurology}, year = {2018}, doi = {10.1001/jamaneurol.2018.1578}, pmid = {29946685}, url = {https://doi.org/10.1001/jamaneurol.2018.1578} } @article{yamamoto2012-22408130, author = {Yamamoto, T. and Kondo, K. and Hirai, H. and Nakade, M. and Aida, J. and Hirata, Y.}, title = {{Association between self-reported dental health status and onset of dementia: a 4-year prospective cohort study of older Japanese adults from the Aichi Gerontological Evaluation Study (AGES) Project}}, journal = {Psychosomatic medicine}, year = {2012}, doi = {10.1097/psy.0b013e318246dffb}, pmid = {22408130}, url = {https://doi.org/10.1097/psy.0b013e318246dffb} } @article{vogt2017-29051531, author = {Vogt, N. M. and Kerby, R. L. and Dill-McFarland, K. A. and Harding, S. J. and Merluzzi, A. P. and Johnson, S. C. and Carlsson, C. M. and Asthana, S. and others}, title = {{Gut microbiome alterations in Alzheimer's disease}}, journal = {Scientific reports}, year = {2017}, doi = {10.1038/s41598-017-13601-y}, pmid = {29051531}, url = {https://doi.org/10.1038/s41598-017-13601-y} } @article{williamsgray2013-23781007, author = {Williams-Gray, C. H. and Mason, S. L. and Evans, JR. and Foltynie, T. and Brayne, C. and Robbins, T. W. and Barker, R. A.}, title = {{The CamPaIGN study of Parkinson's disease: 10-year outlook in an incident population-based cohort}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2013}, doi = {10.1136/jnnp-2013-305277}, pmid = {23781007}, url = {https://doi.org/10.1136/jnnp-2013-305277} } @article{kuan2019-31650125, author = {Kuan, V. and Denaxas, S. and Gonzalez-Izquierdo, A. and Direk, K. and Bhatti, O. and Husain, S. and Sutaria, S. and Hingorani, M. and others}, title = {{A chronological map of 308 physical and mental health conditions from 4 million individuals in the English National Health Service}}, journal = {The Lancet. Digital health}, year = {2019}, doi = {10.1016/s2589-7500(19)30012-3}, pmid = {31650125}, url = {https://doi.org/10.1016/s2589-7500(19)30012-3} } @article{ridha2008-18274807, author = {Ridha, B. H. and Anderson, V. M. and Barnes, J. and Boyes, R. G. and Price, S. L. and Rossor, M. N. and Whitwell, J. L. and Jenkins, L. and others}, title = {{Volumetric MRI and cognitive measures in Alzheimer disease : comparison of markers of progression}}, journal = {Journal of neurology}, year = {2008}, doi = {10.1007/s00415-008-0750-9}, pmid = {18274807}, url = {https://doi.org/10.1007/s00415-008-0750-9} } @article{cash2013-24049139, author = {Cash, D. M. and Ridgway, G. R. and Liang, Y. and Ryan, N. S. and Kinnunen, K. M. and Yeatman, T. and Malone, I. B. and Benzinger, T. L. and others}, title = {{The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study}}, journal = {Neurology}, year = {2013}, doi = {10.1212/wnl.0b013e3182a841c6}, pmid = {24049139}, url = {https://doi.org/10.1212/wnl.0b013e3182a841c6} } @article{chen2021-34537810, author = {Chen, S. D. and Lu, J. Y. and Li, H. Q. and Yang, Y. X. and Jiang, J. H. and Cui, M. and Zuo, C. T. and Tan, L. and others}, title = {{Staging tau pathology with tau PET in Alzheimer's disease: a longitudinal study}}, journal = {Translational psychiatry}, year = {2021}, doi = {10.1038/s41398-021-01602-5}, pmid = {34537810}, url = {https://doi.org/10.1038/s41398-021-01602-5} } @article{cooper2007-17005068, author = {Cooper, C. and Balamurali, T. B. and Livingston, G.}, title = {{A systematic review of the prevalence and covariates of anxiety in caregivers of people with dementia}}, journal = {International psychogeriatrics}, year = {2007}, doi = {10.1017/s1041610206004297}, pmid = {17005068}, url = {https://doi.org/10.1017/s1041610206004297} } @article{leuzy2016-27401520, author = {Leuzy, A. and Chiotis, K. and Hasselbalch, S. G. and Rinne, J. O. and de Mendonça, A. and Otto, M. and Lleó, A. and Castelo-Branco, M. and others}, title = {{Pittsburgh compound B imaging and cerebrospinal fluid amyloid-β in a multicentre European memory clinic study}}, journal = {Brain : a journal of neurology}, year = {2016}, doi = {10.1093/brain/aww160}, pmid = {27401520}, url = {https://doi.org/10.1093/brain/aww160} } @article{compta2011-21596773, author = {Compta, Y. and Parkkinen, L. and O'Sullivan, S. S. and Vandrovcova, J. and Holton, J. L. and Collins, C. and Lashley, T. and Kallis, C. and others}, title = {{Lewy- and Alzheimer-type pathologies in Parkinson's disease dementia: which is more important?}}, journal = {Brain : a journal of neurology}, year = {2011}, doi = {10.1093/brain/awr031}, pmid = {21596773}, url = {https://doi.org/10.1093/brain/awr031} } @article{ridha2006-16987729, author = {Ridha, B. H. and Barnes, J. and Bartlett, J. W. and Godbolt, A. and Pepple, T. and Rossor, M. N. and Fox, N. C.}, title = {{Tracking atrophy progression in familial Alzheimer's disease: a serial MRI study}}, journal = {The Lancet. Neurology}, year = {2006}, doi = {10.1016/s1474-4422(06)70550-6}, pmid = {16987729}, url = {https://doi.org/10.1016/s1474-4422(06)70550-6} } @article{ossenkoppele2021-34254442, author = {Ossenkoppele, R. and Reimand, J. and Smith, R. and Leuzy, A. and Strandberg, O. and Palmqvist, S. and Stomrud, E. and Zetterberg, H. and others}, title = {{Tau PET correlates with different Alzheimer's disease-related features compared to CSF and plasma p-tau biomarkers}}, journal = {EMBO molecular medicine}, year = {2021}, doi = {10.15252/emmm.202114398}, pmid = {34254442}, url = {https://doi.org/10.15252/emmm.202114398} } @article{mancuso2024-38539015, author = {Mancuso, R. and Fattorelli, N. and Martinez-Muriana, A. and Davis, E. and Wolfs, L. and Van Den Daele, J. and Geric, I. and Premereur, J. and others}, title = {{Xenografted human microglia display diverse transcriptomic states in response to Alzheimer's disease-related amyloid-β pathology}}, journal = {Nature neuroscience}, year = {2024}, doi = {10.1038/s41593-024-01600-y}, pmid = {38539015}, url = {https://doi.org/10.1038/s41593-024-01600-y} } @article{cappuyns2025-39709141, author = {Cappuyns, S. and Piqué-Gili, M. and Esteban-Fabró, R. and Philips, G. and Balaseviciute, U. and Pinyol, R. and Gris-Oliver, A. and Vandecaveye, V. and others}, title = {{Single-cell RNA sequencing-derived signatures define response patterns to atezolizumab + bevacizumab in advanced hepatocellular carcinoma}}, journal = {Journal of hepatology}, year = {2025}, doi = {10.1016/j.jhep.2024.12.016}, pmid = {39709141}, url = {https://doi.org/10.1016/j.jhep.2024.12.016} } @article{brosseron2022-34995486, author = {Brosseron, F. and Maass, A. and Kleineidam, L. and Ravichandran, K. A. and González, P. G. and McManus, R. M. and Ising, C. and Santarelli, F. and others}, title = {{Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer's disease}}, journal = {Neuron}, year = {2022}, doi = {10.1016/j.neuron.2021.12.016}, pmid = {34995486}, url = {https://doi.org/10.1016/j.neuron.2021.12.016} } @article{ohrfelt2023-36192174, author = {Öhrfelt, A. and Benedet, A. L. and Ashton, N. J. and Kvartsberg, H. and Vandijck, M. and Weiner, M. W. and Trojanowski, J. Q. and Shaw, L. M. and others}, title = {{Association of CSF GAP-43 With the Rate of Cognitive Decline and Progression to Dementia in Amyloid-Positive Individuals}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000201417}, pmid = {36192174}, url = {https://doi.org/10.1212/wnl.0000000000201417} } @article{lewczuk2018-30055655, author = {Lewczuk, P. and Ermann, N. and Andreasson, U. and Schultheis, C. and Podhorna, J. and Spitzer, P. and Maler, J. M. and Kornhuber, J. and others}, title = {{Plasma neurofilament light as a potential biomarker of neurodegeneration in Alzheimer's disease}}, journal = {Alzheimer's research \& therapy}, year = {2018}, doi = {10.1186/s13195-018-0404-9}, pmid = {30055655}, url = {https://doi.org/10.1186/s13195-018-0404-9} } @article{henry2019-31062029, author = {Henry, A. and Katsoulis, M. and Masi, S. and Fatemifar, G. and Denaxas, S. and Acosta, D. and Garfield, V. and Dale, C. E.}, title = {{The relationship between sleep duration, cognition and dementia: a Mendelian randomization study}}, journal = {International journal of epidemiology}, year = {2019}, doi = {10.1093/ije/dyz071}, pmid = {31062029}, url = {https://doi.org/10.1093/ije/dyz071} } @article{jacobs2020-32934108, author = {Jacobs, B. M. and Belete, D. and Bestwick, J. and Blauwendraat, C. and Bandres-Ciga, S. and Heilbron, K. and Dobson, R. and Nalls, M. A. and others}, title = {{Parkinson's disease determinants, prediction and gene-environment interactions in the UK Biobank}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2020}, doi = {10.1136/jnnp-2020-323646}, pmid = {32934108}, url = {https://doi.org/10.1136/jnnp-2020-323646} } @article{vangennip2021-34588209, author = {van Gennip, A. C. E. and Stehouwer, C. D. A. and van Boxtel, M. P. J. and Verhey, F. R. J. and Koster, A. and Kroon, A. A. and Köhler, S. and van Greevenbroek, M. M. J. and others}, title = {{Association of Type 2 Diabetes, According to the Number of Risk Factors Within Target Range, With Structural Brain Abnormalities, Cognitive Performance, and Risk of Dementia}}, journal = {Diabetes care}, year = {2021}, doi = {10.2337/dc21-0149}, pmid = {34588209}, url = {https://doi.org/10.2337/dc21-0149} } @article{heneka2025-39653749, author = {Heneka, M. T. and van der Flier, W. M. and Jessen, F. and Hoozemanns, J. and Thal, D. R. and Boche, D. and Brosseron, F. and Teunissen, C. and others}, title = {{Neuroinflammation in Alzheimer disease}}, journal = {Nature reviews. Immunology}, year = {2025}, doi = {10.1038/s41577-024-01104-7}, pmid = {39653749}, url = {https://doi.org/10.1038/s41577-024-01104-7} } @article{janelidze2016-26783546, author = {Janelidze, S. and Hertze, J. and Zetterberg, H. and Landqvist Waldö, M. and Santillo, A. and Blennow, K. and Hansson, O.}, title = {{Cerebrospinal fluid neurogranin and YKL-40 as biomarkers of Alzheimer's disease}}, journal = {Annals of clinical and translational neurology}, year = {2016}, doi = {10.1002/acn3.266}, pmid = {26783546}, url = {https://doi.org/10.1002/acn3.266} } @article{kang2025-39773247, author = {Kang, Jae Myeong and Manjavong, Manchumad and Jin, Chengshi and Diaz, Adam and Ashford, Miriam Thiel and Eichenbaum, Joseph and Thorp, Emily and Wragg, Elizabeth and others}, title = {{Subjective cognitive decline predicts longitudinal neuropsychological test performance in an unsupervised online setting in the Brain Health Registry}}, journal = {Alzheimer s Research \& Therapy}, year = {2025}, doi = {10.1186/s13195-024-01641-2}, pmid = {39773247}, url = {https://doi.org/10.1186/s13195-024-01641-2} } @article{lattmann2026-41997924, author = {Lattmann, René and Vockert, Niklas and Bernal, Jose and Wesenberg, Judith and Suksangkharn, Yanin and Yakupov, Renat and Schütze, Hartmut and Glanz, Wenzel and others}, title = {{Dysfunction of the episodic memory network in the Alzheimer’s disease cascade}}, journal = {Nature Communications}, year = {2026}, doi = {10.1038/s41467-026-71831-z}, pmid = {41997924}, url = {https://doi.org/10.1038/s41467-026-71831-z} } @article{dubois2016-27012484, author = {Dubois, Bruno and Hampel, Harald Juergen and Feldman, Howard and Scheltens, Philip and Aisen, Paul S. S. and Andrieu, Sandrine and Bakardjian, Hovagim and Benali, Habib and Bertram, Lars and Blennow, Kaj and Broich, Karl and Cavedo, Enrica and Crutch, Sebastian James and Dartigues, Jean‐François and Duyckaerts, Charles J. and Epelbaum, Stéphane and Frisoni, Giovanni Battista and Gauthier, Serge G. and Genthon, Rémy and Gouw, Alida A. and Habert, Marie‐Odile and Holtzman, David M. and Kivipelto, Miia and Lista, Simone and Molinuevo, José Luís and O’Bryant, Sid E. and Rabinovici, Gil D. and Rowe, Christopher Cleon and Salloway, Stephen and Schneider, Lon S. S. and Sperling, Reisa Anne and Teichmann, Marc and Carrillo, María C. and Cummings, Jeffrey L. and Jack, Clifford R.}, title = {{Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria}}, journal = {Alzheimer s \& Dementia}, year = {2016}, doi = {10.1016/j.jalz.2016.02.002}, pmid = {27012484}, url = {https://doi.org/10.1016/j.jalz.2016.02.002} } @article{hoglinger2017-28467028, author = {Höglinger, Günter U. and Respondek, Gesine and Stamelou, María and Kurz, Carolin and Josephs, Keith A. and Lang, Anthony E. and Mollenhauer, Brit and Müller, Ulrich and Nilsson, Christer and Whitwell, Jennifer L. and Arzberger, Thomas and Englund, Elisabet M. and Gelpí, Ellen and Giese, Armin and Irwin, David John and Meissner, Wassilios G. and Pantelyat, Alexander Y. and Rajput, Alex H. and Van Swieten, John Cornelis and Troakes, Claire and Antonini, Angelo and Bhatia, Kailash P. and Bordelon, Yvette M. and Compta, Yaroslau and Corvol, Jean‐Christophe and Colosimo, Carlo and Dickson, Dennis W. and Dodel, Richard C. and Ferguson, Leslie W. and Grossman, Murray and Kassubek, Jan and Krismer, Florian and Levin, Johannes and Lorenzl, Stefan and Morris, Huw R. and Nestor, Peter J. and Oertel, Wolfgang H. and Poewe, Werner H and Rabinovici, Gil D. and Rowe, James Benedict and Schellenberg, Gerard D. and Seppi, Klaus and van Eimeren, Thilo and Wenning, Gregor Karl and Boxer, Adam L. and Golbe, Lawrence I. and Litvan, Irene and {Movement Disorder Society–endorsed PSP Study Group}}, title = {{Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria}}, journal = {Movement Disorders}, year = {2017}, doi = {10.1002/mds.26987}, pmid = {28467028}, url = {https://doi.org/10.1002/mds.26987} } @article{mackenzie2009-19924424, author = {Mackenzie, Ian R. and Neumann, Manuela and Bigio, Eileen H. and Cairns, Nigel J. and Alafuzoff, Irina I. and Kril, Jillian J. and Kovács, Gábor Géza and Ghetti, Bernardino Francesco and Halliday, Glenda Margaret and Holm, Ida E. and Ince, Paul G. and Kamphorst, Wouter and Révész, Tamás and Rozemüller, Annemieke J.M. and Kumar‐Singh, Samir and Akiyama, Haruhiko and Baborie, Atik and Spina, Salvatore E. and Dickson, Dennis W. and Trojanowski, John Q. and Mann, David}, title = {{Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update}}, journal = {Acta Neuropathologica}, year = {2009}, doi = {10.1007/s00401-009-0612-2}, pmid = {19924424}, url = {https://doi.org/10.1007/s00401-009-0612-2} } @article{good2001-11525331, author = {Good, Catriona D. and Johnsrude, Ingrid S. and Ashburner, John and Henson, Richard N. and Friston, Karl John and Frackowiak, Richard S. J.}, title = {{A Voxel-Based Morphometric Study of Ageing in 465 Normal Adult Human Brains}}, journal = {NeuroImage}, year = {2001}, doi = {10.1006/nimg.2001.0786}, pmid = {11525331}, url = {https://doi.org/10.1006/nimg.2001.0786} } @article{karikari2022-35585226, author = {Karikari, T. K. and Ashton, N. J. and Brinkmalm, G. and Brum, W. S. and Benedet, A. L. and Montoliu-Gaya, L. and Lantero-Rodriguez, J. and Pascoal, T. A. and others}, title = {{Blood phospho-tau in Alzheimer disease: analysis, interpretation, and clinical utility}}, journal = {Nature reviews. Neurology}, year = {2022}, doi = {10.1038/s41582-022-00665-2}, pmid = {35585226}, url = {https://doi.org/10.1038/s41582-022-00665-2} } @article{dewilde2018-29889941, author = {de Wilde, A. and van der Flier, W. M. and Pelkmans, W. and Bouwman, F. and Verwer, J. and Groot, C. and van Buchem, M. M. and Zwan, M. and others}, title = {{Association of Amyloid Positron Emission Tomography With Changes in Diagnosis and Patient Treatment in an Unselected Memory Clinic Cohort: The ABIDE Project}}, journal = {JAMA neurology}, year = {2018}, doi = {10.1001/jamaneurol.2018.1346}, pmid = {29889941}, url = {https://doi.org/10.1001/jamaneurol.2018.1346} } @article{dumurgier2022-35970577, author = {Dumurgier, J. and Sabia, S. and Zetterberg, H. and Teunissen, C. E. and Hanseeuw, B. and Orellana, A. and Schraen, S. and Gabelle, A. and others}, title = {{A Pragmatic, Data-Driven Method to Determine Cutoffs for CSF Biomarkers of Alzheimer Disease Based on Validation Against PET Imaging}}, journal = {Neurology}, year = {2022}, doi = {10.1212/wnl.0000000000200735}, pmid = {35970577}, url = {https://doi.org/10.1212/wnl.0000000000200735} } @article{babapourmofrad2020-32788242, author = {Babapour Mofrad, R. and Tijms, B. M. and Scheltens, P. and Barkhof, F. and van der Flier, W. M. and Sikkes, S. A. M. and Teunissen, C. E.}, title = {{Sex differences in CSF biomarkers vary by Alzheimer disease stage and APOE ε4 genotype}}, journal = {Neurology}, year = {2020}, doi = {10.1212/wnl.0000000000010629}, pmid = {32788242}, url = {https://doi.org/10.1212/wnl.0000000000010629} } @article{walker2015-26595642, author = {Walker, Z. and Possin, K. L. and Boeve, B. F. and Aarsland, D.}, title = {{Lewy body dementias}}, journal = {Lancet (London, England)}, year = {2015}, doi = {10.1016/s0140-6736(15)00462-6}, pmid = {26595642}, url = {https://doi.org/10.1016/s0140-6736(15)00462-6} } @article{coylegilchrist2016-27037234, author = {Coyle-Gilchrist, I. T. and Dick, K. M. and Patterson, K. and Vázquez Rodríquez, P. and Wehmann, E. and Wilcox, A. and Lansdall, C. J. and Dawson, K. E. and others}, title = {{Prevalence, characteristics, and survival of frontotemporal lobar degeneration syndromes}}, journal = {Neurology}, year = {2016}, doi = {10.1212/wnl.0000000000002638}, pmid = {27037234}, url = {https://doi.org/10.1212/wnl.0000000000002638} } @article{kvartsberg2015-25533203, author = {Kvartsberg, H. and Duits, F. H. and Ingelsson, M. and Andreasen, N. and Öhrfelt, A. and Andersson, K. and Brinkmalm, G. and Lannfelt, L. and others}, title = {{Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2015}, doi = {10.1016/j.jalz.2014.10.009}, pmid = {25533203}, url = {https://doi.org/10.1016/j.jalz.2014.10.009} } @article{henneman2009-19289740, author = {Henneman, W. J. and Sluimer, J. D. and Barnes, J. and van der Flier, W. M. and Sluimer, I. C. and Fox, N. C. and Scheltens, P. and Vrenken, H. and others}, title = {{Hippocampal atrophy rates in Alzheimer disease: added value over whole brain volume measures}}, journal = {Neurology}, year = {2009}, doi = {10.1212/01.wnl.0000344568.09360.31}, pmid = {19289740}, url = {https://doi.org/10.1212/01.wnl.0000344568.09360.31} } @article{bunn2014-25358236, author = {Bunn, F. and Burn, A. M. and Goodman, C. and Rait, G. and Norton, S. and Robinson, L. and Schoeman, J. and Brayne, C.}, title = {{Comorbidity and dementia: a scoping review of the literature}}, journal = {BMC medicine}, year = {2014}, doi = {10.1186/s12916-014-0192-4}, pmid = {25358236}, url = {https://doi.org/10.1186/s12916-014-0192-4} } @article{mahoney2012-22366791, author = {Mahoney, C. J. and Beck, J. and Rohrer, J. D. and Lashley, T. and Mok, K. and Shakespeare, T. and Yeatman, T. and Warrington, E. K. and others}, title = {{Frontotemporal dementia with the C9ORF72 hexanucleotide repeat expansion: clinical, neuroanatomical and neuropathological features}}, journal = {Brain : a journal of neurology}, year = {2012}, doi = {10.1093/brain/awr361}, pmid = {22366791}, url = {https://doi.org/10.1093/brain/awr361} } @article{miki2019-31289815, author = {Miki, Y. and Foti, S. C. and Asi, Y. T. and Tsushima, E. and Quinn, N. and Ling, H. and Holton, J. L.}, title = {{Improving diagnostic accuracy of multiple system atrophy: a clinicopathological study}}, journal = {Brain : a journal of neurology}, year = {2019}, doi = {10.1093/brain/awz189}, pmid = {31289815}, url = {https://doi.org/10.1093/brain/awz189} } @article{stamate2019-31890857, author = {Stamate, D. and Kim, M. and Proitsi, P. and Westwood, S. and Baird, A. and Nevado-Holgado, A. and Hye, A. and Bos, I. and others}, title = {{A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2019}, doi = {10.1016/j.trci.2019.11.001}, pmid = {31890857}, url = {https://doi.org/10.1016/j.trci.2019.11.001} } @article{kleinberger2014-24990881, author = {Kleinberger, G. and Yamanishi, Y. and Suárez-Calvet, M. and Czirr, E. and Lohmann, E. and Cuyvers, E. and Struyfs, H. and Pettkus, N. and others}, title = {{TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis}}, journal = {Science translational medicine}, year = {2014}, doi = {10.1126/scitranslmed.3009093}, pmid = {24990881}, url = {https://doi.org/10.1126/scitranslmed.3009093} } @article{mizielinska2014-25103406, author = {Mizielinska, S. and Grönke, S. and Niccoli, T. and Ridler, C. E. and Clayton, E. L. and Devoy, A. and Moens, T. and Norona, F. E. and others}, title = {{C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins}}, journal = {Science (New York, N.Y.)}, year = {2014}, doi = {10.1126/science.1256800}, pmid = {25103406}, url = {https://doi.org/10.1126/science.1256800} } @article{johnson2014-24686783, author = {Johnson, J. O. and Pioro, E. P. and Boehringer, A. and Chia, R. and Feit, H. and Renton, A. E. and Pliner, H. A. and Abramzon, Y. and others}, title = {{Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis}}, journal = {Nature neuroscience}, year = {2014}, doi = {10.1038/nn.3688}, pmid = {24686783}, url = {https://doi.org/10.1038/nn.3688} } @article{mattsson2015-25541191, author = {Mattsson, N. and Insel, P. S. and Donohue, M. and Landau, S. and Jagust, W. J. and Shaw, L. M. and Trojanowski, J. Q. and Zetterberg, H. and others}, title = {{Independent information from cerebrospinal fluid amyloid-β and florbetapir imaging in Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2015}, doi = {10.1093/brain/awu367}, pmid = {25541191}, url = {https://doi.org/10.1093/brain/awu367} } @article{baligacs2024-39639016, author = {Baligács, N. and Albertini, G. and Borrie, S. C. and Serneels, L. and Pridans, C. and Balusu, S. and De Strooper, B.}, title = {{Homeostatic microglia initially seed and activated microglia later reshape amyloid plaques in Alzheimer's Disease}}, journal = {Nature communications}, year = {2024}, doi = {10.1038/s41467-024-54779-w}, pmid = {39639016}, url = {https://doi.org/10.1038/s41467-024-54779-w} } @article{tai2023-36972059, author = {Tai, X. Y. and Torzillo, E. and Lyall, D. M. and Manohar, S. and Husain, M. and Sen, A.}, title = {{Association of Dementia Risk With Focal Epilepsy and Modifiable Cardiovascular Risk Factors}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.0339}, pmid = {36972059}, url = {https://doi.org/10.1001/jamaneurol.2023.0339} } @article{salvado2021-33521872, author = {Salvadó, G. and Grothe, M. J. and Groot, C. and Moscoso, A. and Schöll, M. and Gispert, J. D. and Ossenkoppele, R. and {Alzheimer’s Disease Neuroimaging Initiative}}, title = {{Differential associations of APOE-ε2 and APOE-ε4 alleles with PET-measured amyloid-β and tau deposition in older individuals without dementia}}, journal = {European journal of nuclear medicine and molecular imaging}, year = {2021}, doi = {10.1007/s00259-021-05192-8}, pmid = {33521872}, url = {https://doi.org/10.1007/s00259-021-05192-8} } @article{nyberg2025-39909687, author = {Nyberg, Solja T. and Frank, Philipp and Pentti, Jaana and Alfredsson, Lars S. and Ervasti, Jenni M and Goldberg, Marcel and Knutsson, Anders and Koskinen, Aki and others}, title = {{Health benefits of leisure-time physical activity by socioeconomic status, lifestyle risk, and mental health: a multicohort study}}, journal = {The Lancet Public Health}, year = {2025}, doi = {10.1016/s2468-2667(24)00300-1}, pmid = {39909687}, url = {https://doi.org/10.1016/s2468-2667(24)00300-1} } @article{suemoto2025-40823285, author = {Suemoto, Cláudia Kimie and Borelli, Wyllians Vendramini and Calandri, Ismael Luis and Bertola, Laiss and Castilhos, Raphael Machado and Caramelli, Paulo and Nitríni, Ricardo and Brucki, Sônia Maria Dozzi and others}, title = {{The potential for dementia prevention in Brazil: a population attributable fraction calculation for 14 modifiable risk factors}}, journal = {The Lancet Regional Health - Americas}, year = {2025}, doi = {10.1016/j.lana.2025.101209}, pmid = {40823285}, url = {https://doi.org/10.1016/j.lana.2025.101209} } @article{reyes2025-40318118, author = {Reyes, Ramiro Eduardo Rea and Wilson, Rachael E. and Langhough, Rebecca E. and Studer, Rachel L. and Jonaitis, Erin McMullen and Oomens, Julie Elisabeth and Planalp, Elizabeth M. and Bendlin, Barbara B. and others}, title = {{Targeted proteomic biomarker profiling using NULISA in a cohort enriched with risk for Alzheimer's disease and related dementias}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70166}, pmid = {40318118}, url = {https://doi.org/10.1002/alz.70166} } @article{erickson2026-41557565, author = {Erickson, Pontus and Skillbäck, Tobias Borgh and Kern, Silke and Skoog, I. and Jönsson, Linus and Andréasson, Ulf and Blennow, Kaj and Eriksdotter, Maria and others}, title = {{Limited Diagnostic Performance of Cerebrospinal Fluid Glial Fibrillary Acidic Protein in Dementia}}, journal = {Dementia and Geriatric Cognitive Disorders}, year = {2026}, doi = {10.1159/000550601}, pmid = {41557565}, url = {https://doi.org/10.1159/000550601} } @article{davies2025-40169305, author = {Davies, Nathan and Barrado‐Martín, Yolanda and Aworinde, Jesutofunmi and Vickerstaff, Victoria and Moore, Kirsten J. and Kenten, Charlotte and McMullen, Sarah M. and Evans, Catherine and others}, title = {{A meta-review and synthesis of the effectiveness of psychosocial interventions for people living with dementia nearing the end of life and their family carers}}, journal = {International Psychogeriatrics}, year = {2025}, doi = {10.1016/j.inpsyc.2025.100068}, pmid = {40169305}, url = {https://doi.org/10.1016/j.inpsyc.2025.100068} } @article{khalil2018-30171200, author = {Khalil, Michael and Teunissen, Charlotte Elisabeth and Otto, Markus and Piehl, Fredrik and Sormani, Maria Pia and Gattringer, Thomas and Barro, Christian and Kappos, Ludwig and Comabella, Manuel and Fazekas, Franz and Petzold, Axel and Blennow, Kaj and Zetterberg, Henrik and Kühle, Jens}, title = {{Neurofilaments as biomarkers in neurological disorders}}, journal = {Nature Reviews Neurology}, year = {2018}, doi = {10.1038/s41582-018-0058-z}, pmid = {30171200}, url = {https://doi.org/10.1038/s41582-018-0058-z} } @article{quenez2026-42648288, author = {Quenez, O. and Schramm, C. and Cassinari, K. and Nicolas, A. and Groeneveld, J. and Huguet, G. and Grenier-Boley, B. and Hulsman, M. and Walters, G. B. and de Rojas, I. and Rovelet-Lecrux, A. and Feuillette, S. and others}, title = {{Exome analysis of 22,319 individuals links extremely rare copy-number variants and 22q11.21 dosage to Alzheimer risk}}, journal = {American Journal of Human Genetics}, year = {2026}, doi = {10.1016/j.ajhg.2026.07.013}, pmid = {42648288}, url = {https://doi.org/10.1016/j.ajhg.2026.07.013} } @article{caviedes2026-41688826, author = {Caviedes, A. and Cabral-Miranda, F. and Orellana, P. and Hernández, H. and Henríquez, F. and Gonzalez-Gomez, R. and Pizarro, M. and Migeot, J. and Ochoa-Rosales, C. and Gonzalez-Silva, C. and Marin-Diaz, N. and Coronel-Oliveros, C. and others}, title = {{Blood-based AT(N) biomarkers for Alzheimer's disease and frontotemporal lobar degeneration in Latin America}}, journal = {Nature Aging}, year = {2026}, doi = {10.1038/s43587-025-01061-3}, pmid = {41688826}, url = {https://doi.org/10.1038/s43587-025-01061-3} } @article{skillback2014-25339208, author = {Skillbäck, T. and Farahmand, B. and Bartlett, J. W. and Rosén, C. and Mattsson, N. and Nägga, K. and Kilander, L. and Religa, D. and others}, title = {{CSF neurofilament light differs in neurodegenerative diseases and predicts severity and survival}}, journal = {Neurology}, year = {2014}, doi = {10.1212/wnl.0000000000001015}, pmid = {25339208}, url = {https://doi.org/10.1212/wnl.0000000000001015} } @article{lautner2014-25162367, author = {Lautner, R. and Palmqvist, S. and Mattsson, N. and Andreasson, U. and Wallin, A. and Pålsson, E. and Jakobsson, J. and Herukka, S. K. and others}, title = {{Apolipoprotein E genotype and the diagnostic accuracy of cerebrospinal fluid biomarkers for Alzheimer disease}}, journal = {JAMA psychiatry}, year = {2014}, doi = {10.1001/jamapsychiatry.2014.1060}, pmid = {25162367}, url = {https://doi.org/10.1001/jamapsychiatry.2014.1060} } @article{cooper2014-24888381, author = {Cooper, S. A. and Caslake, M. and Evans, J. and Hassiotis, A. and Jahoda, A. and McConnachie, A. and Morrison, J. and Ring, H. and others}, title = {{Toward onset prevention of cognitive decline in adults with Down syndrome (the TOP-COG study): study protocol for a randomized controlled trial}}, journal = {Trials}, year = {2014}, doi = {10.1186/1745-6215-15-202}, pmid = {24888381}, url = {https://doi.org/10.1186/1745-6215-15-202} } @article{griva2010-20800327, author = {Griva, K. and Stygall, J. and Hankins, M. and Davenport, A. and Harrison, M. and Newman, S. P.}, title = {{Cognitive impairment and 7-year mortality in dialysis patients}}, journal = {American journal of kidney diseases : the official journal of the National Kidney Foundation}, year = {2010}, doi = {10.1053/j.ajkd.2010.07.003}, pmid = {20800327}, url = {https://doi.org/10.1053/j.ajkd.2010.07.003} } @article{hansson2019-31010420, author = {Hansson, O. and Lehmann, S. and Otto, M. and Zetterberg, H. and Lewczuk, P.}, title = {{Advantages and disadvantages of the use of the CSF Amyloid β (Aβ) 42/40 ratio in the diagnosis of Alzheimer's Disease}}, journal = {Alzheimer's research \& therapy}, year = {2019}, doi = {10.1186/s13195-019-0485-0}, pmid = {31010420}, url = {https://doi.org/10.1186/s13195-019-0485-0} } @article{park2013-23495089, author = {Park, J. H. and Seo, S. W. and Kim, C. and Kim, G. H. and Noh, H. J. and Kim, S. T. and Kwak, K. C. and Yoon, U. and others}, title = {{Pathogenesis of cerebral microbleeds: In vivo imaging of amyloid and subcortical ischemic small vessel disease in 226 individuals with cognitive impairment}}, journal = {Annals of neurology}, year = {2013}, doi = {10.1002/ana.23845}, pmid = {23495089}, url = {https://doi.org/10.1002/ana.23845} } @article{cooper2008-18383189, author = {Cooper, C. and Katona, C. and Orrell, M. and Livingston, G.}, title = {{Coping strategies, anxiety and depression in caregivers of people with Alzheimer's disease}}, journal = {International journal of geriatric psychiatry}, year = {2008}, doi = {10.1002/gps.2007}, pmid = {18383189}, url = {https://doi.org/10.1002/gps.2007} } @article{mukadam2011-21157846, author = {Mukadam, N. and Cooper, C. and Livingston, G.}, title = {{A systematic review of ethnicity and pathways to care in dementia}}, journal = {International journal of geriatric psychiatry}, year = {2011}, doi = {10.1002/gps.2484}, pmid = {21157846}, url = {https://doi.org/10.1002/gps.2484} } @article{kalaria2024-38696263, author = {Kalaria, R. and Maestre, G. and Mahinrad, S. and Acosta, D. M. and Akinyemi, R. O. and Alladi, S. and Allegri, R. F. and Arshad, F. and others}, title = {{The 2022 symposium on dementia and brain aging in low- and middle-income countries: Highlights on research, diagnosis, care, and impact}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.13836}, pmid = {38696263}, url = {https://doi.org/10.1002/alz.13836} } @article{coutrot2019-30883560, author = {Coutrot, A. and Schmidt, S. and Coutrot, L. and Pittman, J. and Hong, L. and Wiener, J. M. and Hölscher, C. and Dalton, R. C. and others}, title = {{Virtual navigation tested on a mobile app is predictive of real-world wayfinding navigation performance}}, journal = {PloS one}, year = {2019}, doi = {10.1371/journal.pone.0213272}, pmid = {30883560}, url = {https://doi.org/10.1371/journal.pone.0213272} } @article{volkmer2020-31134821, author = {Volkmer, A. and Spector, A. and Meitanis, V. and Warren, J. D. and Beeke, S.}, title = {{Effects of functional communication interventions for people with primary progressive aphasia and their caregivers: a systematic review}}, journal = {Aging \& mental health}, year = {2020}, doi = {10.1080/13607863.2019.1617246}, pmid = {31134821}, url = {https://doi.org/10.1080/13607863.2019.1617246} } @article{skibinski2005-16041373, author = {Skibinski, G. and Parkinson, N. J. and Brown, J. M. and Chakrabarti, L. and Lloyd, S. L. and Hummerich, H. and Nielsen, J. E. and Hodges, JR. and others}, title = {{Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia}}, journal = {Nature genetics}, year = {2005}, doi = {10.1038/ng1609}, pmid = {16041373}, url = {https://doi.org/10.1038/ng1609} } @article{fisher2019-31541187, author = {Fisher, C. K. and Smith, A. M. and Walsh, JR. and Diseases, Coalition Against Major and Abbott and {Alliance for Aging Research} and {Alzheimer’s Association} and {Alzheimer’s Foundation of America} and others}, title = {{Machine learning for comprehensive forecasting of Alzheimer's Disease progression}}, journal = {Scientific reports}, year = {2019}, doi = {10.1038/s41598-019-49656-2}, pmid = {31541187}, url = {https://doi.org/10.1038/s41598-019-49656-2} } @article{woollacott2018-30111356, author = {Woollacott, I. O. C. and Nicholas, J. M. and Heslegrave, A. and Heller, C. and Foiani, M. S. and Dick, K. M. and Russell, L. L. and Paterson, R. W. and others}, title = {{Cerebrospinal fluid soluble TREM2 levels in frontotemporal dementia differ by genetic and pathological subgroup}}, journal = {Alzheimer's research \& therapy}, year = {2018}, doi = {10.1186/s13195-018-0405-8}, pmid = {30111356}, url = {https://doi.org/10.1186/s13195-018-0405-8} } @article{quesnel2024-37992295, author = {Quesnel, M. J. and Labonté, A. and Picard, C. and Zetterberg, H. and Blennow, K. and Brinkmalm, A. and Villeneuve, S. and Poirier, J. and others}, title = {{Insulin-like growth factor binding protein-2 in at-risk adults and autopsy-confirmed Alzheimer brains}}, journal = {Brain : a journal of neurology}, year = {2024}, doi = {10.1093/brain/awad398}, pmid = {37992295}, url = {https://doi.org/10.1093/brain/awad398} } @article{karran2022-35177833, author = {Karran, E. and De Strooper, B.}, title = {{The amyloid hypothesis in Alzheimer disease: new insights from new therapeutics}}, journal = {Nature reviews. Drug discovery}, year = {2022}, doi = {10.1038/s41573-022-00391-w}, pmid = {35177833}, url = {https://doi.org/10.1038/s41573-022-00391-w} } @article{heller2020-31937580, author = {Heller, C. and Foiani, M. S. and Moore, K. and Convery, R. and Bocchetta, M. and Neason, M. and Cash, D. M. and Thomas, D. and others}, title = {{Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2020}, doi = {10.1136/jnnp-2019-321954}, pmid = {31937580}, url = {https://doi.org/10.1136/jnnp-2019-321954} } @article{chan2003-14550701, author = {Chan, D. and Janssen, J. C. and Whitwell, J. L. and Watt, H. C. and Jenkins, R. and Frost, C. and Rossor, M. N. and Fox, N. C.}, title = {{Change in rates of cerebral atrophy over time in early-onset Alzheimer's disease: longitudinal MRI study}}, journal = {Lancet (London, England)}, year = {2003}, doi = {10.1016/s0140-6736(03)14469-8}, pmid = {14550701}, url = {https://doi.org/10.1016/s0140-6736(03)14469-8} } @article{garfield2021-33464682, author = {Garfield, V. and Farmaki, A. E. and Eastwood, S. V. and Mathur, R. and Rentsch, C. T. and Bhaskaran, K. and Smeeth, L. and Chaturvedi, N.}, title = {{HbA1c and brain health across the entire glycaemic spectrum}}, journal = {Diabetes, obesity \& metabolism}, year = {2021}, doi = {10.1111/dom.14321}, pmid = {33464682}, url = {https://doi.org/10.1111/dom.14321} } @article{anaturk2023-37603383, author = {Anatürk, M. and Patel, R. and Ebmeier, K. P. and Georgiopoulos, G. and Newby, D. and Topiwala, A. and de Lange, A. G. and Cole, J. H. and others}, title = {{Development and validation of a dementia risk score in the UK Biobank and Whitehall II cohorts}}, journal = {BMJ mental health}, year = {2023}, doi = {10.1136/bmjment-2023-300719}, pmid = {37603383}, url = {https://doi.org/10.1136/bmjment-2023-300719} } @article{rohrer2011-21908872, author = {Rohrer, J. D. and Lashley, T. and Schott, J. M. and Warren, J. E. and Mead, S. and Isaacs, A. M. and Beck, J. and Hardy, J. and others}, title = {{Clinical and neuroanatomical signatures of tissue pathology in frontotemporal lobar degeneration}}, journal = {Brain : a journal of neurology}, year = {2011}, doi = {10.1093/brain/awr198}, pmid = {21908872}, url = {https://doi.org/10.1093/brain/awr198} } @article{webster2009-19361613, author = {Webster, J. A. and Gibbs, JR. and Clarke, J. and Ray, M. and Zhang, W. and Holmans, P. and Rohrer, K. and Zhao, A. and others}, title = {{Genetic control of human brain transcript expression in Alzheimer disease}}, journal = {American journal of human genetics}, year = {2009}, doi = {10.1016/j.ajhg.2009.03.011}, pmid = {19361613}, url = {https://doi.org/10.1016/j.ajhg.2009.03.011} } @article{prudencio2020-32790644, author = {Prudencio, M. and Humphrey, J. and Pickles, S. and Brown, A. L. and Hill, S. E. and Kachergus, J. M. and Shi, J. and Heckman, M. G. and others}, title = {{Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia}}, journal = {The Journal of clinical investigation}, year = {2020}, doi = {10.1172/jci139741}, pmid = {32790644}, url = {https://doi.org/10.1172/jci139741} } @article{destrooper2016-26871627, author = {De Strooper, B. and Karran, E.}, title = {{The Cellular Phase of Alzheimer's Disease}}, journal = {Cell}, year = {2016}, doi = {10.1016/j.cell.2015.12.056}, pmid = {26871627}, url = {https://doi.org/10.1016/j.cell.2015.12.056} } @article{gabb2025-40435500, author = {Gabb, Victoria Grace and Blackman, Jonathan and Morrison, Hamish Duncan and Li, Haoxuan and Kendrick, Adrian Hugh and Turner, Nicholas L and Greenwood, Rosemary and Biswas, Bijetri and others}, title = {{Longitudinal Remote Sleep and Cognitive Research in Older Adults With Mild Cognitive Impairment and Dementia: Prospective Feasibility Cohort Study}}, journal = {JMIR Aging}, year = {2025}, doi = {10.2196/72824}, pmid = {40435500}, url = {https://doi.org/10.2196/72824} } @article{gao2026-41548525, author = {Gao, Yaqing and Zaninotto, Paola and Steptoe, Andrew}, title = {{Associations of self- and informant-reported functional impairment with cognitive performance and incident dementia}}, journal = {The Journal of Prevention of Alzheimer s Disease}, year = {2026}, doi = {10.1016/j.tjpad.2026.100482}, pmid = {41548525}, url = {https://doi.org/10.1016/j.tjpad.2026.100482} } @article{zhang2025-40906862, author = {Zhang, Xiaodi and Liu, Haiqing and Wu, Xiao Jun and Jia, Longgang and Gadhave, Kundlik and Wang, Lena and Zhang, Kevin and others}, title = {{Lewy body dementia promotion by air pollutants}}, journal = {Science}, year = {2025}, doi = {10.1126/science.adu4132}, pmid = {40906862}, url = {https://doi.org/10.1126/science.adu4132} } @article{luo2025-40437158, author = {Luo, Hao and Koponen, Marjaana and Roethlein, Christoph and Becker, Cornelia and Bell, J. Simon and Beyene, Kebede Abera and Chai, Yi and Chan, Amy Hai Yan and others}, title = {{A multinational cohort study of trends in survival following dementia diagnosis}}, journal = {Communications Medicine}, year = {2025}, doi = {10.1038/s43856-025-00923-6}, pmid = {40437158}, url = {https://doi.org/10.1038/s43856-025-00923-6} } @article{liu2025-39903689, author = {Liu, Haiyan and Marsh, Thomas W. and Shi, Xinyu and Renton, Alan Edward and Bowling, Kevin M. and Ziegemeier, Ellen and Wang, Guoqiao and Cao, Yuchen and others}, title = {{The landscape of autosomal-dominant Alzheimer’s disease: global distribution and age of onset}}, journal = {Brain}, year = {2025}, doi = {10.1093/brain/awaf038}, pmid = {39903689}, url = {https://doi.org/10.1093/brain/awaf038} } @article{groot2026-41990307, author = {Groot, Colin and Calandri, Ismael L. and Bader, Ilse and Bocancea, Diana I. and de Bruin, Hannah and Carrigan, Maria and Collij, Lyduine Eisa and Duits, Flora Hillegonde and others}, title = {{Characterizing Individuals Fulfilling Clinical Criteria for Limbic-Predominant Age-Related TDP-43 Encephalopathy in a Tertiary Memory Clinic}}, journal = {Neurology}, year = {2026}, doi = {10.1212/wnl.0000000000214810}, pmid = {41990307}, url = {https://doi.org/10.1212/wnl.0000000000214810} } @article{howard2025-41447406, author = {Howard, Connie and Sommerlad, Andrew and Livingston, Gill and Fernández‐Sanlés, Alba}, title = {{The effects of psychosocial interventions on reducing hospitalisation in people with dementia: an umbrella review}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz70858_100202}, pmid = {41447406}, url = {https://doi.org/10.1002/alz70858_100202} } @article{dicaro2026-41943055, author = {Di Caro, V. and Cho, E. and Thiel, J. and Lizama, B. N. and Koel-Simmelink, M. J. A. and Pandey, K. and Duong, D. and Seyfried, N. T. and others}, title = {{Impact of zervimesine on the neuroinflammatory biomarker GFAP and related proteomic molecular correlates in plasma of participants from a phase 2 clinical trial in Alzheimer's disease}}, journal = {Alzheimer's research \& therapy}, year = {2026}, doi = {10.1186/s13195-026-02025-4}, pmid = {41943055}, url = {https://doi.org/10.1186/s13195-026-02025-4} } @article{deng2026-41559195, author = {Deng, Zhenhong and Yang, Yuxin and Lin, Queran and Xiao, Songhua and Zuo, You and Wang, Jinyuan and Xu, Yongteng and Li, Honghong and others}, title = {{Population attributable fractions of a wide range of peripheral diseases for the burden of dementia}}, journal = {Nature human behaviour}, year = {2026}, doi = {10.1038/s41562-025-02392-2}, pmid = {41559195}, url = {https://doi.org/10.1038/s41562-025-02392-2} } @article{xia2026-41920501, author = {Xia, X. and Eriksdotter, M. and Clark, A. and Brogaard, N. J. and Gundgaard, J. and Polavieja, P. and Skajaa, N. and Zetterberg, H. and Kern, S. and Skillbäck, T. B. and Jönsson, L.}, title = {{Utilization and Lifetime Costs of Formal Care for Alzheimer's Disease Dementia in Sweden}}, journal = {PharmacoEconomics}, year = {2026}, doi = {10.1007/s40273-026-01612-5}, pmid = {41920501}, url = {https://doi.org/10.1007/s40273-026-01612-5} } @article{therriault2024-38429551, author = {Therriault, J. and Schindler, S. E. and Salvadó, G. and Pascoal, T. A. and Benedet, A. L. and Ashton, N. J. and Karikari, T. K. and Apostolova, L. and others}, title = {{Biomarker-based staging of Alzheimer disease: rationale and clinical applications}}, journal = {Nature reviews. Neurology}, year = {2024}, doi = {10.1038/s41582-024-00942-2}, pmid = {38429551}, url = {https://doi.org/10.1038/s41582-024-00942-2} } @article{morris2022-35580594, author = {Morris, J. C. and Weiner, M. and Xiong, C. and Beckett, L. and Coble, D. and Saito, N. and Aisen, P. S. and Allegri, R. and others}, title = {{Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology}}, journal = {Brain : a journal of neurology}, year = {2022}, doi = {10.1093/brain/awac181}, pmid = {35580594}, url = {https://doi.org/10.1093/brain/awac181} } @article{okello2009-19587325, author = {Okello, A. and Koivunen, J. and Edison, P. and Archer, H. A. and Turkheimer, F. E. and Någren, K. and Bullock, R. and Walker, Z. and others}, title = {{Conversion of amyloid positive and negative MCI to AD over 3 years: an 11C-PIB PET study}}, journal = {Neurology}, year = {2009}, doi = {10.1212/wnl.0b013e3181b23564}, pmid = {19587325}, url = {https://doi.org/10.1212/wnl.0b013e3181b23564} } @article{desikan2017-28323831, author = {Desikan, R. S. and Fan, C. C. and Wang, Y. and Schork, A. J. and Cabral, H. J. and Cupples, L. A. and Thompson, W. K. and Besser, L. and others}, title = {{Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score}}, journal = {PLoS medicine}, year = {2017}, doi = {10.1371/journal.pmed.1002258}, pmid = {28323831}, url = {https://doi.org/10.1371/journal.pmed.1002258} } @article{fong2015-26139023, author = {Fong, T. G. and Davis, D. and Growdon, M. E. and Albuquerque, A. and Inouye, S. K.}, title = {{The interface between delirium and dementia in elderly adults}}, journal = {The Lancet. Neurology}, year = {2015}, doi = {10.1016/s1474-4422(15)00101-5}, pmid = {26139023}, url = {https://doi.org/10.1016/s1474-4422(15)00101-5} } @article{greaves2019-31119452, author = {Greaves, C. V. and Rohrer, J. D.}, title = {{An update on genetic frontotemporal dementia}}, journal = {Journal of neurology}, year = {2019}, doi = {10.1007/s00415-019-09363-4}, pmid = {31119452}, url = {https://doi.org/10.1007/s00415-019-09363-4} } @article{griffiths2020-32871106, author = {Griffiths, T. D. and Lad, M. and Kumar, S. and Holmes, E. and McMurray, B. and Maguire, E. A. and Billig, A. J. and Sedley, W.}, title = {{How Can Hearing Loss Cause Dementia?}}, journal = {Neuron}, year = {2020}, doi = {10.1016/j.neuron.2020.08.003}, pmid = {32871106}, url = {https://doi.org/10.1016/j.neuron.2020.08.003} } @article{sommerlad2023-37202513, author = {Sommerlad, A. and Kivimäki, M. and Larson, E. B. and Röhr, S. and Shirai, K. and Singh-Manoux, A. and Livingston, G.}, title = {{Social participation and risk of developing dementia}}, journal = {Nature aging}, year = {2023}, doi = {10.1038/s43587-023-00387-0}, pmid = {37202513}, url = {https://doi.org/10.1038/s43587-023-00387-0} } @article{frisoni2010-20139996, author = {Frisoni, G. B. and Fox, N. C. and Jack, C. R. and Scheltens, P. and Thompson, P. M.}, title = {{The clinical use of structural MRI in Alzheimer disease}}, journal = {Nature reviews. Neurology}, year = {2010}, doi = {10.1038/nrneurol.2009.215}, pmid = {20139996}, url = {https://doi.org/10.1038/nrneurol.2009.215} } @article{berg2014-24619848, author = {Berg, D. and Postuma, R. B. and Bloem, B. and Chan, P. and Dubois, B. and Gasser, T. and Goetz, C. G. and Halliday, G. M. and others}, title = {{Time to redefine PD? Introductory statement of the MDS Task Force on the definition of Parkinson's disease}}, journal = {Movement disorders : official journal of the Movement Disorder Society}, year = {2014}, doi = {10.1002/mds.25844}, pmid = {24619848}, url = {https://doi.org/10.1002/mds.25844} } @article{chard2021-33437067, author = {Chard, D. T. and Alahmadi, A. A. S. and Audoin, B. and Charalambous, T. and Enzinger, C. and Hulst, H. E. and Rocca, M. A. and À, Rovira and others}, title = {{Mind the gap: from neurons to networks to outcomes in multiple sclerosis}}, journal = {Nature reviews. Neurology}, year = {2021}, doi = {10.1038/s41582-020-00439-8}, pmid = {33437067}, url = {https://doi.org/10.1038/s41582-020-00439-8} } @article{mattsson2018-29321235, author = {Mattsson, N. and Smith, R. and Strandberg, O. and Palmqvist, S. and Schöll, M. and Insel, P. S. and Hägerström, D. and Ohlsson, T. and others}, title = {{Comparing 18F-AV-1451 with CSF t-tau and p-tau for diagnosis of Alzheimer disease}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000004887}, pmid = {29321235}, url = {https://doi.org/10.1212/wnl.0000000000004887} } @article{castellazzi2020-32595465, author = {Castellazzi, G. and Cuzzoni, M. G. and Cotta Ramusino, M. and Martinelli, D. and Denaro, F. and Ricciardi, A. and Vitali, P. and Anzalone, N. and others}, title = {{A Machine Learning Approach for the Differential Diagnosis of Alzheimer and Vascular Dementia Fed by MRI Selected Features}}, journal = {Frontiers in neuroinformatics}, year = {2020}, doi = {10.3389/fninf.2020.00025}, pmid = {32595465}, url = {https://doi.org/10.3389/fninf.2020.00025} } @article{keezer2016-26549780, author = {Keezer, M. R. and Sisodiya, S. M. and Sander, J. W.}, title = {{Comorbidities of epilepsy: current concepts and future perspectives}}, journal = {The Lancet. Neurology}, year = {2016}, doi = {10.1016/s1474-4422(15)00225-2}, pmid = {26549780}, url = {https://doi.org/10.1016/s1474-4422(15)00225-2} } @article{chan2013-22407743, author = {Chan, D. and Livingston, G. and Jones, L. and Sampson, E. L.}, title = {{Grief reactions in dementia carers: a systematic review}}, journal = {International journal of geriatric psychiatry}, year = {2013}, doi = {10.1002/gps.3795}, pmid = {22407743}, url = {https://doi.org/10.1002/gps.3795} } @article{parra2021-33634602, author = {Parra, M. A. and Baez, S. and Sedeño, L. and Gonzalez Campo, C. and Santamaría-García, H. and Aprahamian, I. and Bertolucci, P. H. and Bustin, J. and others}, title = {{Dementia in Latin America: Paving the way toward a regional action plan}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2021}, doi = {10.1002/alz.12202}, pmid = {33634602}, url = {https://doi.org/10.1002/alz.12202} } @article{wagen2022-36102775, author = {Wagen, A. Z. and Coath, W. and Keshavan, A. and James, S. N. and Parker, T. D. and Lane, C. A. and Buchanan, S. M. and Keuss, S. E. and others}, title = {{Life course, genetic, and neuropathological associations with brain age in the 1946 British Birth Cohort: a population-based study}}, journal = {The lancet. Healthy longevity}, year = {2022}, doi = {10.1016/s2666-7568(22)00167-2}, pmid = {36102775}, url = {https://doi.org/10.1016/s2666-7568(22)00167-2} } @article{lyall2023-37496259, author = {Lyall, D. M. and Kormilitzin, A. and Lancaster, C. and Sousa, J. and Petermann-Rocha, F. and Buckley, C. and Harshfield, E. L. and Iveson, M. H. and others}, title = {{Artificial intelligence for dementia-Applied models and digital health}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2023}, doi = {10.1002/alz.13391}, pmid = {37496259}, url = {https://doi.org/10.1002/alz.13391} } @article{weil2016-27412389, author = {Weil, R. S. and Schrag, A. E. and Warren, J. D. and Crutch, S. J. and Lees, A. J. and Morris, H. R.}, title = {{Visual dysfunction in Parkinson's disease}}, journal = {Brain : a journal of neurology}, year = {2016}, doi = {10.1093/brain/aww175}, pmid = {27412389}, url = {https://doi.org/10.1093/brain/aww175} } @article{kac2025-40275833, author = {Kac, P. R. and Alcolea, D. and Montoliu-Gaya, L. and Fernández, S. and Rodriguez, J. L. and Maure, L. and González-Ortiz, F. and Benejam, B. and others}, title = {{Plasma p-tau212 as a biomarker of sporadic and Down syndrome Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.70172}, pmid = {40275833}, url = {https://doi.org/10.1002/alz.70172} } @article{mummery2000-10632099, author = {Mummery, C. J. and Patterson, K. and Price, C. J. and Ashburner, J. and Frackowiak, R. S. and Hodges, JR.}, title = {{A voxel-based morphometry study of semantic dementia: relationship between temporal lobe atrophy and semantic memory}}, journal = {Annals of neurology}, year = {2000}, doi = {10.1002/1531-8249(200001)47:1<36::aid-ana8>3.0.co;2-l}, pmid = {10632099}, url = {https://doi.org/10.1002/1531-8249(200001)47:1<36::aid-ana8>3.0.co;2-l} } @article{rosen2013-23800368, author = {Rosén, C. and Hansson, O. and Blennow, K. and Zetterberg, H.}, title = {{Fluid biomarkers in Alzheimer's disease - current concepts}}, journal = {Molecular neurodegeneration}, year = {2013}, doi = {10.1186/1750-1326-8-20}, pmid = {23800368}, url = {https://doi.org/10.1186/1750-1326-8-20} } @article{slattery2014-25160042, author = {Slattery, C. F. and Beck, J. A. and Harper, L. and Adamson, G. and Abdi, Z. and Uphill, J. and Campbell, T. and Druyeh, R. and others}, title = {{R47H TREM2 variant increases risk of typical early-onset Alzheimer's disease but not of prion or frontotemporal dementia}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2014}, doi = {10.1016/j.jalz.2014.05.1751}, pmid = {25160042}, url = {https://doi.org/10.1016/j.jalz.2014.05.1751} } @article{ali2022-35617280, author = {Ali, M. and Sung, Y. J. and Wang, F. and Fernández, M. V. and Morris, J. C. and Fagan, A. M. and Blennow, K. and Zetterberg, H. and others}, title = {{Leveraging large multi-center cohorts of Alzheimer disease endophenotypes to understand the role of Klotho heterozygosity on disease risk}}, journal = {PloS one}, year = {2022}, doi = {10.1371/journal.pone.0267298}, pmid = {35617280}, url = {https://doi.org/10.1371/journal.pone.0267298} } @article{zettergren2019-30792413, author = {Zettergren, A. and Höglund, K. and Kern, S. and Thorvaldsson, V. and Johan Skoog, M. and Hansson, O. and Andreasen, N. and Bogdanovic, N. and others}, title = {{Association of IL1RAP-related genetic variation with cerebrospinal fluid concentration of Alzheimer-associated tau protein}}, journal = {Scientific reports}, year = {2019}, doi = {10.1038/s41598-018-36650-3}, pmid = {30792413}, url = {https://doi.org/10.1038/s41598-018-36650-3} } @article{schrag2012-22019547, author = {Schrag, A. and Schott, J. M. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{What is the clinically relevant change on the ADAS-Cog?}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2012}, doi = {10.1136/jnnp-2011-300881}, pmid = {22019547}, url = {https://doi.org/10.1136/jnnp-2011-300881} } @article{jones2010-21085570, author = {Jones, L. and Holmans, P. A. and Hamshere, M. L. and Harold, D. and Moskvina, V. and Ivanov, D. and Pocklington, A. and Abraham, R. and others}, title = {{Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease}}, journal = {PloS one}, year = {2010}, doi = {10.1371/journal.pone.0013950}, pmid = {21085570}, url = {https://doi.org/10.1371/journal.pone.0013950} } @article{charidimou2015-26115675, author = {Charidimou, A. and Linn, J. and Vernooij, M. W. and Opherk, C. and Akoudad, S. and Baron, J. C. and Greenberg, S. M. and Jäger, H. R. and others}, title = {{Cortical superficial siderosis: detection and clinical significance in cerebral amyloid angiopathy and related conditions}}, journal = {Brain : a journal of neurology}, year = {2015}, doi = {10.1093/brain/awv162}, pmid = {26115675}, url = {https://doi.org/10.1093/brain/awv162} } @article{skillback2015-26133663, author = {Skillbäck, T. and Farahmand, B. Y. and Rosén, C. and Mattsson, N. and Nägga, K. and Kilander, L. and Religa, D. and Wimo, A. and others}, title = {{Cerebrospinal fluid tau and amyloid-β1-42 in patients with dementia}}, journal = {Brain : a journal of neurology}, year = {2015}, doi = {10.1093/brain/awv181}, pmid = {26133663}, url = {https://doi.org/10.1093/brain/awv181} } @article{patani2023-37308616, author = {Patani, R. and Hardingham, G. E. and Liddelow, S. A.}, title = {{Functional roles of reactive astrocytes in neuroinflammation and neurodegeneration}}, journal = {Nature reviews. Neurology}, year = {2023}, doi = {10.1038/s41582-023-00822-1}, pmid = {37308616}, url = {https://doi.org/10.1038/s41582-023-00822-1} } @article{bartels2020-33004513, author = {Bartels, T. and De Schepper, S. and Hong, S.}, title = {{Microglia modulate neurodegeneration in Alzheimer's and Parkinson's diseases}}, journal = {Science (New York, N.Y.)}, year = {2020}, doi = {10.1126/science.abb8587}, pmid = {33004513}, url = {https://doi.org/10.1126/science.abb8587} } @article{oomens2025-39841474, author = {Oomens, Julie Elisabeth and van Gils, Veerle and Vos, Stephanie J. B. and Freeze, Whitney M. and Maserejian, Nancy Nairi and Curiale, Gioacchino G. and Gillis, Cai and Boada, Merçé and others}, title = {{Cerebral Microbleeds and Amyloid Pathology Estimates From the Amyloid Biomarker Study}}, journal = {JAMA Network Open}, year = {2025}, doi = {10.1001/jamanetworkopen.2024.55571}, pmid = {39841474}, url = {https://doi.org/10.1001/jamanetworkopen.2024.55571} } @article{smith2025-40967729, author = {Smith, Holly Christina and Petersen, Irene and Hayes, Joseph and Jordan, Kelvin P. and Boman, Magnus and Banerjee, Sube and Walters, Kate R and Cooper, Claudia and others}, title = {{Antipsychotic prescriptions in people with dementia in primary care: a cohort study investigating adherence of dose and duration to UK clinical guidelines}}, journal = {The Lancet Psychiatry}, year = {2025}, doi = {10.1016/s2215-0366(25)00261-5}, pmid = {40967729}, url = {https://doi.org/10.1016/s2215-0366(25)00261-5} } @article{aaronson2025-40249614, author = {Aaronson, Anna and Diaz, Adam and Ashford, Miriam Thiel and Jin, Chengshi and Tank, Rachana and Miller, Melanie Jayne and Kang, Jae Myeong and Manjavong, Manchumad and others}, title = {{Self- and Informant-Report Cognitive Decline Discordance and Mild Cognitive Impairment Diagnosis}}, journal = {JAMA Network Open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.5810}, pmid = {40249614}, url = {https://doi.org/10.1001/jamanetworkopen.2025.5810} } @article{donaghy2025-40156325, author = {Donaghy, Paul C. and Hasoon, Jahfer and Hamilton, Calum Alexander and Ciafone, Joanna and Durcan, Rory and Barnett, Nicola A. and Olsen, Kirsty and Lawley, Sarah and others}, title = {{Plasma Biomarkers and Disease Prognosis in Mild Cognitive Impairment with Lewy Bodies}}, journal = {Movement Disorders}, year = {2025}, doi = {10.1002/mds.30181}, pmid = {40156325}, url = {https://doi.org/10.1002/mds.30181} } @article{kroger2025-40962877, author = {Kröger, Benjamin and Wang, Hui‐Xin and Ekblom, Örjan B. and Wu, Jing and Westerlund, Hugo and Kivimäki, Mika and Wang, Rui}, title = {{Outdoor physical activity, residential green spaces and the risk of dementia in the UK Biobank cohort}}, journal = {Communications Medicine}, year = {2025}, doi = {10.1038/s43856-025-01130-z}, pmid = {40962877}, url = {https://doi.org/10.1038/s43856-025-01130-z} } @article{brycesmith2025-41120751, author = {Bryce-Smith, Sam and Brown, Anna‐Leigh and Chien, Max Z. Y. J. and Dattilo, Dario and Mehta, Puja R. and Mattedi, Francesca and Barattucci, Simone and Mikheenko, Alla and others}, title = {{TDP-43 loss induces cryptic polyadenylation in ALS/FTD}}, journal = {Nature Neuroscience}, year = {2025}, doi = {10.1038/s41593-025-02050-w}, pmid = {41120751}, url = {https://doi.org/10.1038/s41593-025-02050-w} } @article{ashburner2000-10860804, author = {Ashburner, John and Friston, Karl John}, title = {{Voxel-Based Morphometry—The Methods}}, journal = {NeuroImage}, year = {2000}, doi = {10.1006/nimg.2000.0582}, pmid = {10860804}, url = {https://doi.org/10.1006/nimg.2000.0582} } @article{ashburner2005-15955494, author = {Ashburner, John and Friston, Karl John}, title = {{Unified segmentation}}, journal = {NeuroImage}, year = {2005}, doi = {10.1016/j.neuroimage.2005.02.018}, pmid = {15955494}, url = {https://doi.org/10.1016/j.neuroimage.2005.02.018} } @article{pelkmans2024-37690071, author = {Pelkmans, W. and Shekari, M. and Brugulat-Serrat, A. and Sánchez-Benavides, G. and Minguillón, C. and Fauria, K. and Molinuevo, J. L. and Grau-Rivera, O. and others}, title = {{Astrocyte biomarkers GFAP and YKL-40 mediate early Alzheimer's disease progression}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.13450}, pmid = {37690071}, url = {https://doi.org/10.1002/alz.13450} } @article{merluzzi2018-29959263, author = {Merluzzi, A. P. and Carlsson, C. M. and Johnson, S. C. and Schindler, S. E. and Asthana, S. and Blennow, K. and Zetterberg, H. and Bendlin, B. B.}, title = {{Neurodegeneration, synaptic dysfunction, and gliosis are phenotypic of Alzheimer dementia}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000005901}, pmid = {29959263}, url = {https://doi.org/10.1212/wnl.0000000000005901} } @article{leonenko2019-31199530, author = {Leonenko, G. and Shoai, M. and Bellou, E. and Sims, R. and Williams, J. and Hardy, J. and Escott-Price, V. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{Genetic risk for alzheimer disease is distinct from genetic risk for amyloid deposition}}, journal = {Annals of neurology}, year = {2019}, doi = {10.1002/ana.25530}, pmid = {31199530}, url = {https://doi.org/10.1002/ana.25530} } @article{voevodskaya2016-27164711, author = {Voevodskaya, O. and Sundgren, P. C. and Strandberg, O. and Zetterberg, H. and Minthon, L. and Blennow, K. and Wahlund, L. O. and Westman, E. and others}, title = {{Myo-inositol changes precede amyloid pathology and relate to APOE genotype in Alzheimer disease}}, journal = {Neurology}, year = {2016}, doi = {10.1212/wnl.0000000000002672}, pmid = {27164711}, url = {https://doi.org/10.1212/wnl.0000000000002672} } @article{frisoni2023-36895446, author = {Frisoni, G. B. and Altomare, D. and Ribaldi, F. and Villain, N. and Brayne, C. and Mukadam, N. and Abramowicz, M. and Barkhof, F. and others}, title = {{Dementia prevention in memory clinics: recommendations from the European task force for brain health services}}, journal = {The Lancet regional health. Europe}, year = {2023}, doi = {10.1016/j.lanepe.2022.100576}, pmid = {36895446}, url = {https://doi.org/10.1016/j.lanepe.2022.100576} } @article{williams2005-15788542, author = {Williams, D. R. and de Silva, R. and Paviour, D. C. and Pittman, A. and Watt, H. C. and Kilford, L. and Holton, J. L. and Revesz, T. and others}, title = {{Characteristics of two distinct clinical phenotypes in pathologically proven progressive supranuclear palsy: Richardson's syndrome and PSP-parkinsonism}}, journal = {Brain : a journal of neurology}, year = {2005}, doi = {10.1093/brain/awh488}, pmid = {15788542}, url = {https://doi.org/10.1093/brain/awh488} } @article{bourgeat2010-20065247, author = {Bourgeat, P. and Chételat, G. and Villemagne, V. L. and Fripp, J. and Raniga, P. and Pike, K. and Acosta, O. and Szoeke, C. and others}, title = {{Beta-amyloid burden in the temporal neocortex is related to hippocampal atrophy in elderly subjects without dementia}}, journal = {Neurology}, year = {2010}, doi = {10.1212/wnl.0b013e3181c918b5}, pmid = {20065247}, url = {https://doi.org/10.1212/wnl.0b013e3181c918b5} } @article{lee2014-24554306, author = {Lee, M. J. and Seo, S. W. and Na, D. L. and Kim, C. and Park, J. H. and Kim, G. H. and Kim, C. H. and Noh, Y. and others}, title = {{Synergistic effects of ischemia and β-amyloid burden on cognitive decline in patients with subcortical vascular mild cognitive impairment}}, journal = {JAMA psychiatry}, year = {2014}, doi = {10.1001/jamapsychiatry.2013.4506}, pmid = {24554306}, url = {https://doi.org/10.1001/jamapsychiatry.2013.4506} } @article{gonzalezortiz2023-36927491, author = {Gonzalez-Ortiz, F. and Kac, P. R. and Brum, W. S. and Zetterberg, H. and Blennow, K. and Karikari, T. K.}, title = {{Plasma phospho-tau in Alzheimer's disease: towards diagnostic and therapeutic trial applications}}, journal = {Molecular neurodegeneration}, year = {2023}, doi = {10.1186/s13024-023-00605-8}, pmid = {36927491}, url = {https://doi.org/10.1186/s13024-023-00605-8} } @article{gleason2022-34870885, author = {Gleason, C. E. and Zuelsdorff, M. and Gooding, D. C. and Kind, A. J. H. and Johnson, A. L. and James, T. T. and Lambrou, N. H. and Wyman, M. F. and others}, title = {{Alzheimer's disease biomarkers in Black and non-Hispanic White cohorts: A contextualized review of the evidence}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2022}, doi = {10.1002/alz.12511}, pmid = {34870885}, url = {https://doi.org/10.1002/alz.12511} } @article{kloppel2008-18835868, author = {Klöppel, S. and Stonnington, C. M. and Barnes, J. and Chen, F. and Chu, C. and Good, C. D. and Mader, I. and Mitchell, L. A. and others}, title = {{Accuracy of dementia diagnosis: a direct comparison between radiologists and a computerized method}}, journal = {Brain : a journal of neurology}, year = {2008}, doi = {10.1093/brain/awn239}, pmid = {18835868}, url = {https://doi.org/10.1093/brain/awn239} } @article{oxtoby2017-28520598, author = {Oxtoby, N. P. and Alexander, D. C. and {EuroPOND consortium}}, title = {{Imaging plus X: multimodal models of neurodegenerative disease}}, journal = {Current opinion in neurology}, year = {2017}, doi = {10.1097/wco.0000000000000460}, pmid = {28520598}, url = {https://doi.org/10.1097/wco.0000000000000460} } @article{montoliugaya2025-40595720, author = {Montoliu-Gaya, L. and Bian, S. and Dammer, E. B. and Alcolea, D. and Sauer, M. and Martá-Ariza, M. and Ashton, N. J. and Belbin, O. and others}, title = {{Proteomic analysis of Down syndrome cerebrospinal fluid compared to late-onset and autosomal dominant Alzheimer´s disease}}, journal = {Nature communications}, year = {2025}, doi = {10.1038/s41467-025-61054-z}, pmid = {40595720}, url = {https://doi.org/10.1038/s41467-025-61054-z} } @article{filimonenko2007-17984323, author = {Filimonenko, M. and Stuffers, S. and Raiborg, C. and Yamamoto, A. and Malerød, L. and Fisher, E. M. and Isaacs, A. and Brech, A. and others}, title = {{Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease}}, journal = {The Journal of cell biology}, year = {2007}, doi = {10.1083/jcb.200702115}, pmid = {17984323}, url = {https://doi.org/10.1083/jcb.200702115} } @article{lee2013-24290757, author = {Lee, Y. B. and Chen, H. J. and Peres, J. N. and Gomez-Deza, J. and Attig, J. and Stalekar, M. and Troakes, C. and Nishimura, A. L. and others}, title = {{Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic}}, journal = {Cell reports}, year = {2013}, doi = {10.1016/j.celrep.2013.10.049}, pmid = {24290757}, url = {https://doi.org/10.1016/j.celrep.2013.10.049} } @article{young2014-25012224, author = {Young, A. L. and Oxtoby, N. P. and Daga, P. and Cash, D. M. and Fox, N. C. and Ourselin, S. and Schott, J. M. and Alexander, D. C. and others}, title = {{A data-driven model of biomarker changes in sporadic Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2014}, doi = {10.1093/brain/awu176}, pmid = {25012224}, url = {https://doi.org/10.1093/brain/awu176} } @article{athauda2022-35699244, author = {Athauda, D. and Evans, J. and Wernick, A. and Virdi, G. and Choi, M. L. and Lawton, M. and Vijiaratnam, N. and Girges, C. and others}, title = {{The Impact of Type 2 Diabetes in Parkinson's Disease}}, journal = {Movement disorders : official journal of the Movement Disorder Society}, year = {2022}, doi = {10.1002/mds.29122}, pmid = {35699244}, url = {https://doi.org/10.1002/mds.29122} } @article{ma2018-30239611, author = {MÁ, Araque Caballero and Suárez-Calvet, M. and Duering, M. and Franzmeier, N. and Benzinger, T. and Fagan, A. M. and Bateman, R. J. and Jack, C. R. and others}, title = {{White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2018}, doi = {10.1093/brain/awy229}, pmid = {30239611}, url = {https://doi.org/10.1093/brain/awy229} } @article{ruedacarrasco2023-37575021, author = {Rueda-Carrasco, J. and Sokolova, D. and Lee, S. E. and Childs, T. and Jurčáková, N. and Crowley, G. and De Schepper, S. and Ge, J. Z. and others}, title = {{Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models}}, journal = {The EMBO journal}, year = {2023}, doi = {10.15252/embj.2022113246}, pmid = {37575021}, url = {https://doi.org/10.15252/embj.2022113246} } @article{suarezcalvet2020-33169916, author = {Suárez-Calvet, M. and Karikari, T. K. and Ashton, N. J. and Lantero Rodríguez, J. and Milà-Alomà, M. and Gispert, J. D. and Salvadó, G. and others}, title = {{Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer's continuum when only subtle changes in Aβ pathology are detected}}, journal = {EMBO molecular medicine}, year = {2020}, doi = {10.15252/emmm.202012921}, pmid = {33169916}, url = {https://doi.org/10.15252/emmm.202012921} } @article{halbgebauer2026-41665901, author = {Halbgebauer, R. and Gonzalez-Ortiz, F. and Mayer, B. and Berger, C. and Bergmann, C. and Rinderknecht, H. and Barth, E. and Wohlgemuth, L. and others}, title = {{Blood-Based Analysis of Different Tau Variants in Patients With Multiple Traumatic Injuries}}, journal = {JAMA network open}, year = {2026}, doi = {10.1001/jamanetworkopen.2025.58573}, pmid = {41665901}, url = {https://doi.org/10.1001/jamanetworkopen.2025.58573} } @article{biondo2022-36087560, author = {Biondo, F. and Jewell, A. and Pritchard, M. and Aarsland, D. and Steves, C. J. and Mueller, C. and Cole, J. H.}, title = {{Brain-age is associated with progression to dementia in memory clinic patients}}, journal = {NeuroImage. Clinical}, year = {2022}, doi = {10.1016/j.nicl.2022.103175}, pmid = {36087560}, url = {https://doi.org/10.1016/j.nicl.2022.103175} } @article{elovainio2022-35197341, author = {Elovainio, M. and Lahti, J. and Pirinen, M. and Pulkki-Råback, L. and Malmberg, A. and Lipsanen, J. and Virtanen, M. and Kivimäki, M. and others}, title = {{Association of social isolation, loneliness and genetic risk with incidence of dementia: UK Biobank Cohort Study}}, journal = {BMJ open}, year = {2022}, doi = {10.1136/bmjopen-2021-053936}, pmid = {35197341}, url = {https://doi.org/10.1136/bmjopen-2021-053936} } @article{dimolfetta2026-42573994, author = {Di Molfetta, Guglielmo and Brum, Wagner Scheeren and Pola, Ilaria and Tan, Kübra and Benedet, Andréa Lessa and Sauer, Mathias and Montoliu‐Gaya, Laia and Janelidze, Shorena and others}, title = {{Plasma Biomarkers for Neocortical Tau Burden}}, journal = {JAMA Neurology}, year = {2026}, doi = {10.1001/jamaneurol.2026.2650}, pmid = {42573994}, url = {https://doi.org/10.1001/jamaneurol.2026.2650} }