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@article{buddhaeberlein2022-35542991,
  author  = {Budd Haeberlein, S. and Aisen, P. S. and Barkhof, F. and Chalkias, S. and Chen, T. and Cohen, S. and Dent, G. and Hansson, O. and others},
  title   = {{Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer's Disease}},
  journal = {The journal of prevention of Alzheimer's disease},
  year    = {2022},
  doi     = {10.14283/jpad.2022.30},
  pmid    = {35542991},
  url     = {https://doi.org/10.14283/jpad.2022.30}
}

@article{cummings2025-39780249,
  author  = {Cummings, J. L. and Atri, A. and Feldman, H. H. and Hansson, O. and Sano, M. and Knop, F. K. and Johannsen, P. and León, T. and others},
  title   = {{evoke and evoke+: design of two large-scale, double-blind, placebo-controlled, phase 3 studies evaluating efficacy, safety, and tolerability of semaglutide in early-stage symptomatic Alzheimer's disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2025},
  doi     = {10.1186/s13195-024-01666-7},
  pmid    = {39780249},
  url     = {https://doi.org/10.1186/s13195-024-01666-7}
}

@article{warmenhoven2025-39468767,
  author  = {Warmenhoven, N. and Salvadó, G. and Janelidze, S. and Mattsson-Carlgren, N. and Bali, D. and Orduña Dolado, A. and Kolb, H. and Triana-Baltzer, G. and Barthélemy, N. R. and Schindler, S. E. and Aschenbrenner, A. J. and Raji, C. A. and others},
  title   = {{A comprehensive head-to-head comparison of key plasma phosphorylated tau 217 biomarker tests}},
  journal = {Brain},
  year    = {2025},
  doi     = {10.1093/brain/awae346},
  pmid    = {39468767},
  url     = {https://doi.org/10.1093/brain/awae346}
}

@article{ossenkoppele2025-40155777,
  author  = {Ossenkoppele, R. and Salvadó, G. and Janelidze, S. and Pichet Binette, A. and Bali, D. and Karlsson, L. and Palmqvist, S. and Mattsson-Carlgren, N. and Stomrud, E. and Therriault, J. and Rahmouni, N. and Rosa-Neto, P. and others},
  title   = {{Plasma p-tau217 and tau-PET predict future cognitive decline among cognitively unimpaired individuals: implications for clinical trials}},
  journal = {Nature Aging},
  year    = {2025},
  doi     = {10.1038/s43587-025-00835-z},
  pmid    = {40155777},
  url     = {https://doi.org/10.1038/s43587-025-00835-z}
}

@article{mattssoncarlgren2023-36745413,
  author  = {Mattsson-Carlgren, N. and Salvadó, G. and Ashton, N. J. and Tideman, P. and Stomrud, E. and Zetterberg, H. and Ossenkoppele, R. and Betthauser, T. J. and others},
  title   = {{Prediction of Longitudinal Cognitive Decline in Preclinical Alzheimer Disease Using Plasma Biomarkers}},
  journal = {JAMA neurology},
  year    = {2023},
  doi     = {10.1001/jamaneurol.2022.5272},
  pmid    = {36745413},
  url     = {https://doi.org/10.1001/jamaneurol.2022.5272}
}

@article{karikari2020-32333900,
  author  = {Karikari, T. K. and Pascoal, T. A. and Ashton, N. J. and Janelidze, S. and Benedet, A. L. and Rodriguez, J. L. and Chamoun, M. and Savard, M. and others},
  title   = {{Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts}},
  journal = {The Lancet. Neurology},
  year    = {2020},
  doi     = {10.1016/s1474-4422(20)30071-5},
  pmid    = {32333900},
  url     = {https://doi.org/10.1016/s1474-4422(20)30071-5}
}

@article{pereira2021-34259835,
  author  = {Pereira, J. B. and Janelidze, S. and Smith, R. and Mattsson-Carlgren, N. and Palmqvist, S. and Teunissen, C. E. and Zetterberg, H. and Stomrud, E. and others},
  title   = {{Plasma GFAP is an early marker of amyloid-β but not tau pathology in Alzheimer's disease}},
  journal = {Brain : a journal of neurology},
  year    = {2021},
  doi     = {10.1093/brain/awab223},
  pmid    = {34259835},
  url     = {https://doi.org/10.1093/brain/awab223}
}

@article{brum2023-37653254,
  author  = {Brum, W. S. and Cullen, N. C. and Janelidze, S. and Ashton, N. J. and Zimmer, E. R. and Therriault, J. and Benedet, A. L. and Rahmouni, N. and Tissot, C. and Stevenson, J. and Servaes, S. and Triana-Baltzer, G. and others},
  title   = {{A two-step workflow based on plasma p-tau217 to screen for amyloid β positivity with further confirmatory testing only in uncertain cases}},
  journal = {Nature Aging},
  year    = {2023},
  doi     = {10.1038/s43587-023-00471-5},
  pmid    = {37653254},
  url     = {https://doi.org/10.1038/s43587-023-00471-5}
}

@article{mattssoncarlgren2024-38048096,
  author  = {Mattsson-Carlgren, N. and Collij, L. E. and Stomrud, E. and Pichet Binette, A. and Ossenkoppele, R. and Smith, R. and Karlsson, L. and Lantero-Rodriguez, J. and Snellman, A. and Strandberg, O. and Palmqvist, S. and Ashton, N. J. and others},
  title   = {{Plasma Biomarker Strategy for Selecting Patients With Alzheimer Disease for Antiamyloid Immunotherapies}},
  journal = {JAMA Neurology},
  year    = {2024},
  doi     = {10.1001/jamaneurol.2023.4596},
  pmid    = {38048096},
  url     = {https://doi.org/10.1001/jamaneurol.2023.4596}
}

@article{palmqvist2020-32722745,
  author  = {Palmqvist, S. and Janelidze, S. and Quiroz, Y. T. and Zetterberg, H. and Lopera, F. and Stomrud, E. and Su, Y. and Chen, Y. and others},
  title   = {{Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders}},
  journal = {JAMA},
  year    = {2020},
  doi     = {10.1001/jama.2020.12134},
  pmid    = {32722745},
  url     = {https://doi.org/10.1001/jama.2020.12134}
}

@article{ossenkoppele2021-34180956,
  author  = {Ossenkoppele, R. and Smith, R. and Mattsson-Carlgren, N. and Groot, C. and Leuzy, A. and Strandberg, O. and Palmqvist, S. and Olsson, T. and others},
  title   = {{Accuracy of Tau Positron Emission Tomography as a Prognostic Marker in Preclinical and Prodromal Alzheimer Disease: A Head-to-Head Comparison Against Amyloid Positron Emission Tomography and Magnetic Resonance Imaging}},
  journal = {JAMA neurology},
  year    = {2021},
  doi     = {10.1001/jamaneurol.2021.1858},
  pmid    = {34180956},
  url     = {https://doi.org/10.1001/jamaneurol.2021.1858}
}

@article{oh2025-40164724,
  author  = {Oh, H. S. and Urey, D. Y. and Karlsson, L. and Zhu, Z. and Shen, Y. and Farinas, A. and Timsina, J. and Duggan, M. R. and others},
  title   = {{A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer's disease}},
  journal = {Nature medicine},
  year    = {2025},
  doi     = {10.1038/s41591-025-03565-2},
  pmid    = {40164724},
  url     = {https://doi.org/10.1038/s41591-025-03565-2}
}

@article{janelidze2024-39068669,
  author  = {Janelidze, S. and Barthélemy, N. R. and Salvadó, G. and Schindler, S. E. and Palmqvist, S. and Mattsson-Carlgren, N. and Braunstein, J. B. and Ovod, V. and Bollinger, J. G. and He, Y. and Li, Y. and Raji, C. A. and others},
  title   = {{Plasma Phosphorylated Tau 217 and Aβ42/40 to Predict Early Brain Aβ Accumulation in People Without Cognitive Impairment}},
  journal = {JAMA Neurology},
  year    = {2024},
  doi     = {10.1001/jamaneurol.2024.2619},
  pmid    = {39068669},
  url     = {https://doi.org/10.1001/jamaneurol.2024.2619}
}

@article{mattsson2019-31009028,
  author  = {Mattsson, N. and Cullen, N. C. and Andreasson, U. and Zetterberg, H. and Blennow, K.},
  title   = {{Association Between Longitudinal Plasma Neurofilament Light and Neurodegeneration in Patients With Alzheimer Disease}},
  journal = {JAMA neurology},
  year    = {2019},
  doi     = {10.1001/jamaneurol.2019.0765},
  pmid    = {31009028},
  url     = {https://doi.org/10.1001/jamaneurol.2019.0765}
}

@article{bergeron2018-30255971,
  author  = {Bergeron, D. and Gorno-Tempini, M. L. and Rabinovici, G. D. and Santos-Santos, M. A. and Seeley, W. and Miller, B. L. and Pijnenburg, Y. and Keulen, M. A. and others},
  title   = {{Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia}},
  journal = {Annals of neurology},
  year    = {2018},
  doi     = {10.1002/ana.25333},
  pmid    = {30255971},
  url     = {https://doi.org/10.1002/ana.25333}
}

@article{coughlan2025-40029638,
  author  = {Coughlan, G. T. and Klinger, H. M. and Boyle, R. and Betthauser, T. J. and Binette, A. P. and Christenson, L. and Chadwick, T. and Hansson, O. and others},
  title   = {{Sex Differences in Longitudinal Tau-PET in Preclinical Alzheimer Disease: A Meta-Analysis}},
  journal = {JAMA neurology},
  year    = {2025},
  doi     = {10.1001/jamaneurol.2025.0013},
  pmid    = {40029638},
  url     = {https://doi.org/10.1001/jamaneurol.2025.0013}
}

@article{ossenkoppele2022-36357681,
  author  = {Ossenkoppele, R. and Pichet Binette, A. and Groot, C. and Smith, R. and Strandberg, O. and Palmqvist, S. and Stomrud, E. and Tideman, P. and others},
  title   = {{Amyloid and tau PET-positive cognitively unimpaired individuals are at high risk for future cognitive decline}},
  journal = {Nature medicine},
  year    = {2022},
  doi     = {10.1038/s41591-022-02049-x},
  pmid    = {36357681},
  url     = {https://doi.org/10.1038/s41591-022-02049-x}
}

@article{moscoso2025-40522652,
  author  = {Moscoso, Alexis and Heeman, Fiona and Raghavan, Sheelakumari and Costoya‐Sánchez, Alejandro and van Essen, Martijn and Mainta, Ismini and Camacho, Valle and Rodríguez-Fonseca, Omar Darío and others},
  title   = {{Frequency and Clinical Outcomes Associated With Tau Positron Emission Tomography Positivity}},
  journal = {JAMA},
  year    = {2025},
  doi     = {10.1001/jama.2025.7817},
  pmid    = {40522652},
  url     = {https://doi.org/10.1001/jama.2025.7817}
}

@article{mattsson2017-28346578,
  author  = {Mattsson, N. and Andreasson, U. and Zetterberg, H. and Blennow, K. and {Alzheimer’s Disease Neuroimaging Initiative}},
  title   = {{Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer Disease}},
  journal = {JAMA neurology},
  year    = {2017},
  doi     = {10.1001/jamaneurol.2016.6117},
  pmid    = {28346578},
  url     = {https://doi.org/10.1001/jamaneurol.2016.6117}
}

@article{janelidze2021-33165506,
  author  = {Janelidze, S. and Berron, D. and Smith, R. and Strandberg, O. and Proctor, N. K. and Dage, J. L. and Stomrud, E. and Palmqvist, S. and others},
  title   = {{Associations of Plasma Phospho-Tau217 Levels With Tau Positron Emission Tomography in Early Alzheimer Disease}},
  journal = {JAMA neurology},
  year    = {2021},
  doi     = {10.1001/jamaneurol.2020.4201},
  pmid    = {33165506},
  url     = {https://doi.org/10.1001/jamaneurol.2020.4201}
}

@article{janelidze2020-32123385,
  author  = {Janelidze, S. and Mattsson, N. and Palmqvist, S. and Smith, R. and Beach, T. G. and Serrano, G. E. and Chai, X. and Proctor, N. K. and others},
  title   = {{Plasma P-tau181 in Alzheimer's disease: relationship to other biomarkers, differential diagnosis, neuropathology and longitudinal progression to Alzheimer's dementia}},
  journal = {Nature medicine},
  year    = {2020},
  doi     = {10.1038/s41591-020-0755-1},
  pmid    = {32123385},
  url     = {https://doi.org/10.1038/s41591-020-0755-1}
}

@article{janelidze2020-32246036,
  author  = {Janelidze, S. and Stomrud, E. and Smith, R. and Palmqvist, S. and Mattsson, N. and Airey, D. C. and Proctor, N. K. and Chai, X. and others},
  title   = {{Cerebrospinal fluid p-tau217 performs better than p-tau181 as a biomarker of Alzheimer's disease}},
  journal = {Nature communications},
  year    = {2020},
  doi     = {10.1038/s41467-020-15436-0},
  pmid    = {32246036},
  url     = {https://doi.org/10.1038/s41467-020-15436-0}
}

@article{mattssoncarlgren2020-33068398,
  author  = {Mattsson-Carlgren, N. and Janelidze, S. and Palmqvist, S. and Cullen, N. and Svenningsson, A. L. and Strandberg, O. and Mengel, D. and Walsh, D. M. and others},
  title   = {{Longitudinal plasma p-tau217 is increased in early stages of Alzheimer's disease}},
  journal = {Brain : a journal of neurology},
  year    = {2020},
  doi     = {10.1093/brain/awaa286},
  pmid    = {33068398},
  url     = {https://doi.org/10.1093/brain/awaa286}
}

@article{rabinovici2025-39776249,
  author  = {Rabinovici, G. D. and Knopman, D. S. and Arbizu, J. and Benzinger, T. L. S. and Donohoe, K. J. and Hansson, O. and Herscovitch, P. and Kuo, P. H. and Lingler, J. H. and Minoshima, S. and others},
  title   = {{Updated appropriate use criteria for amyloid and tau PET: A report from the Alzheimer's Association and Society for Nuclear Medicine and Molecular Imaging Workgroup}},
  journal = {Alzheimer's \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.14338},
  pmid    = {39776249},
  url     = {https://doi.org/10.1002/alz.14338}
}

@article{barthelemy2024-38382645,
  author  = {Barthélemy, N. R. and Salvadó, G. and Schindler, S. E. and He, Y. and Janelidze, S. and Collij, L. E. and Saef, B. and Henson, R. L. and others},
  title   = {{Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests}},
  journal = {Nature medicine},
  year    = {2024},
  doi     = {10.1038/s41591-024-02869-z},
  pmid    = {38382645},
  url     = {https://doi.org/10.1038/s41591-024-02869-z}
}

@article{sims2023-37459141,
  author  = {Sims, JR. and Zimmer, J. A. and Evans, C. D. and Lu, M. and Ardayfio, P. and Sparks, J. and Wessels, A. M. and Shcherbinin, S. and others},
  title   = {{Donanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial}},
  journal = {JAMA},
  year    = {2023},
  doi     = {10.1001/jama.2023.13239},
  pmid    = {37459141},
  url     = {https://doi.org/10.1001/jama.2023.13239}
}

@article{mattsson2016-27694257,
  author  = {Mattsson, N. and Zetterberg, H. and Janelidze, S. and Insel, P. S. and Andreasson, U. and Stomrud, E. and Palmqvist, S. and Baker, D. and others},
  title   = {{Plasma tau in Alzheimer disease}},
  journal = {Neurology},
  year    = {2016},
  doi     = {10.1212/wnl.0000000000003246},
  pmid    = {27694257},
  url     = {https://doi.org/10.1212/wnl.0000000000003246}
}

@article{palmqvist2025-40729527,
  author  = {Palmqvist, S. and Whitson, H. E. and Allen, L. A. and Suarez-Calvet, M. and Galasko, D. and Karikari, T. K. and Okrahvi, H. R. and Paczynski, M. and Schindler, S. E. and Teunissen, C. E. and others},
  title   = {{Alzheimer's Association Clinical Practice Guideline on the use of blood-based biomarkers in the diagnostic workup of suspected Alzheimer's disease within specialized care settings}},
  journal = {Alzheimer's \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70535},
  pmid    = {40729527},
  url     = {https://doi.org/10.1002/alz.70535}
}

@article{janelidze2018-30054439,
  author  = {Janelidze, S. and Mattsson, N. and Stomrud, E. and Lindberg, O. and Palmqvist, S. and Zetterberg, H. and Blennow, K. and Hansson, O.},
  title   = {{CSF biomarkers of neuroinflammation and cerebrovascular dysfunction in early Alzheimer disease}},
  journal = {Neurology},
  year    = {2018},
  doi     = {10.1212/wnl.0000000000006082},
  pmid    = {30054439},
  url     = {https://doi.org/10.1212/wnl.0000000000006082}
}

@article{mattssoncarlgren2026-41864233,
  author  = {Mattsson-Carlgren, Niklas and Palmqvist, Sebastian and Horie, Kanta and Barthélemy, Nicolas and Salvadó, Gemma and Binette, Alexa Pichet and Tideman, Pontus and Morris, John C and others},
  title   = {{Integration of plasma eMTBR-tau243 and p-tau217 in the diagnosis and stratification of Alzheimer's disease: a prospective cohort study}},
  journal = {The Lancet. Neurology},
  year    = {2026},
  doi     = {10.1016/S1474-4422(26)00029-3},
  pmid    = {41864233},
  url     = {https://doi.org/10.1016/S1474-4422(26)00029-3}
}

@article{salvado2025-40952756,
  author  = {Salvadó, G. and Janelidze, S. and Bali, D. and Dolado, A. O. and Therriault, J. and Brum, W. S. and Pichet Binette, A. and Stomrud, E. and Mattsson-Carlgren, N. and Palmqvist, S. and Coomans, E. M. and Teunissen, C. E. and others},
  title   = {{Plasma Phosphorylated Tau 217 to Identify Preclinical Alzheimer Disease}},
  journal = {JAMA Neurology},
  year    = {2025},
  doi     = {10.1001/jamaneurol.2025.3217},
  pmid    = {40952756},
  url     = {https://doi.org/10.1001/jamaneurol.2025.3217}
}

@article{palmqvist2024-39068545,
  author  = {Palmqvist, S. and Tideman, P. and Mattsson-Carlgren, N. and Schindler, S. E. and Smith, R. and Ossenkoppele, R. and Calling, S. and West, T. and others},
  title   = {{Blood Biomarkers to Detect Alzheimer Disease in Primary Care and Secondary Care}},
  journal = {JAMA},
  year    = {2024},
  doi     = {10.1001/jama.2024.13855},
  pmid    = {39068545},
  url     = {https://doi.org/10.1001/jama.2024.13855}
}

@article{leuzy2022-34928318,
  author  = {Leuzy, A. and Smith, R. and Cullen, N. C. and Strandberg, O. and Vogel, J. W. and Binette, A. P. and Borroni, E. and Janelidze, S. and others},
  title   = {{Biomarker-Based Prediction of Longitudinal Tau Positron Emission Tomography in Alzheimer Disease}},
  journal = {JAMA neurology},
  year    = {2022},
  doi     = {10.1001/jamaneurol.2021.4654},
  pmid    = {34928318},
  url     = {https://doi.org/10.1001/jamaneurol.2021.4654}
}

@article{ashton2023-36877496,
  author  = {Ashton, N. J. and Moseby-Knappe, M. and Benedet, A. L. and Grötschel, L. and Lantero-Rodriguez, J. and Karikari, T. K. and Hassager, C. and Wise, M. P. and others},
  title   = {{Alzheimer Disease Blood Biomarkers in Patients With Out-of-Hospital Cardiac Arrest}},
  journal = {JAMA neurology},
  year    = {2023},
  doi     = {10.1001/jamaneurol.2023.0050},
  pmid    = {36877496},
  url     = {https://doi.org/10.1001/jamaneurol.2023.0050}
}

@article{janelidze2023-36087307,
  author  = {Janelidze, S. and Bali, D. and Ashton, N. J. and Barthélemy, N. R. and Vanbrabant, J. and Stoops, E. and Vanmechelen, E. and others},
  title   = {{Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer's disease}},
  journal = {Brain : a journal of neurology},
  year    = {2023},
  doi     = {10.1093/brain/awac333},
  pmid    = {36087307},
  url     = {https://doi.org/10.1093/brain/awac333}
}

@article{janelidze2021-34542571,
  author  = {Janelidze, S. and Teunissen, C. E. and Zetterberg, H. and Allué, J. A. and Sarasa, L. and Eichenlaub, U. and Bittner, T. and Ovod, V. and others},
  title   = {{Head-to-Head Comparison of 8 Plasma Amyloid-β 42/40 Assays in Alzheimer Disease}},
  journal = {JAMA neurology},
  year    = {2021},
  doi     = {10.1001/jamaneurol.2021.3180},
  pmid    = {34542571},
  url     = {https://doi.org/10.1001/jamaneurol.2021.3180}
}

@article{palmqvist2016-26936941,
  author  = {Palmqvist, S. and Mattsson, N. and Hansson, O. and {Alzheimer’s Disease Neuroimaging Initiative}},
  title   = {{Cerebrospinal fluid analysis detects cerebral amyloid-β accumulation earlier than positron emission tomography}},
  journal = {Brain : a journal of neurology},
  year    = {2016},
  doi     = {10.1093/brain/aww015},
  pmid    = {26936941},
  url     = {https://doi.org/10.1093/brain/aww015}
}

@article{palmqvist2019-31233127,
  author  = {Palmqvist, S. and Janelidze, S. and Stomrud, E. and Zetterberg, H. and Karl, J. and Zink, K. and Bittner, T. and Mattsson, N. and others},
  title   = {{Performance of Fully Automated Plasma Assays as Screening Tests for Alzheimer Disease-Related β-Amyloid Status}},
  journal = {JAMA neurology},
  year    = {2019},
  doi     = {10.1001/jamaneurol.2019.1632},
  pmid    = {31233127},
  url     = {https://doi.org/10.1001/jamaneurol.2019.1632}
}

@article{ossenkoppele2018-30326496,
  author  = {Ossenkoppele, R. and Rabinovici, G. D. and Smith, R. and Cho, H. and Schöll, M. and Strandberg, O. and Palmqvist, S. and Mattsson, N. and others},
  title   = {{Discriminative Accuracy of [18F]flortaucipir Positron Emission Tomography for Alzheimer Disease vs Other Neurodegenerative Disorders}},
  journal = {JAMA},
  year    = {2018},
  doi     = {10.1001/jama.2018.12917},
  pmid    = {30326496},
  url     = {https://doi.org/10.1001/jama.2018.12917}
}

@article{vandenberghe2010-20687209,
  author  = {Vandenberghe, R. and Van Laere, K. and Ivanoiu, A. and Salmon, E. and Bastin, C. and Triau, E. and Hasselbalch, S. and Law, I. and others},
  title   = {{18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: a phase 2 trial}},
  journal = {Annals of neurology},
  year    = {2010},
  doi     = {10.1002/ana.22068},
  pmid    = {20687209},
  url     = {https://doi.org/10.1002/ana.22068}
}

@article{ashton2021-34099648,
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@article{collij2024-39277604,
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@article{janelidze2023-36987840,
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@article{salvado2024-38514824,
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@article{salvado2026-42189519,
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@article{cicognola2021-33773595,
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  title   = {{Associations of CSF PDGFRβ With Aging, Blood-Brain Barrier Damage, Neuroinflammation, and Alzheimer Disease Pathologic Changes}},
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@article{bolsewig2025-39881147,
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@article{an2026-41917159,
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