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% Source: https://alzhub.org/research?institution=I204250578
% 222 entries, in the order the page lists them. Built from alzhub.org's own records.
% 0 entries have no readable author in the source record and carry no author field.

@article{naj2011-21460841,
  author  = {Naj, A. C. and Jun, G. and Beecham, G. W. and Wang, L. S. and Vardarajan, B. N. and Buros, J. and Gallins, P. J. and Buxbaum, J. D. and others},
  title   = {{Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease}},
  journal = {Nature genetics},
  year    = {2011},
  doi     = {10.1038/ng.801},
  pmid    = {21460841},
  url     = {https://doi.org/10.1038/ng.801}
}

@article{blazhenets2026-42441390,
  author  = {Blazhenets, Ganna and Soleimani-Meigooni, David N and Chiotis, Konstantinos and Allen, Isabel E and Rabinovici, Gil D and La Joie, Renaud and {Meta-Centiloid Study Group} and Apostolova, Liana G and others},
  title   = {{Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis}},
  journal = {JAMA},
  year    = {2026},
  doi     = {10.1001/jama.2026.13116},
  pmid    = {42441390},
  url     = {https://doi.org/10.1001/jama.2026.13116}
}

@article{rajabli2025-40676597,
  author  = {Rajabli, F. and Benchek, P. and Tosto, G. and Kushch, N. and Sha, J. and Bazemore, K. and Zhu, C. and Lee, W. P. and others},
  title   = {{Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease}},
  journal = {Genome biology},
  year    = {2025},
  doi     = {10.1186/s13059-025-03564-z},
  pmid    = {40676597},
  url     = {https://doi.org/10.1186/s13059-025-03564-z}
}

@article{grill2020-32777010,
  author  = {Grill, J. D. and Raman, R. and Ernstrom, K. and Sultzer, D. L. and Burns, J. M. and Donohue, M. C. and Johnson, K. A. and Aisen, P. S. and others},
  title   = {{Short-term Psychological Outcomes of Disclosing Amyloid Imaging Results to Research Participants Who Do Not Have Cognitive Impairment}},
  journal = {JAMA neurology},
  year    = {2020},
  doi     = {10.1001/jamaneurol.2020.2734},
  pmid    = {32777010},
  url     = {https://doi.org/10.1001/jamaneurol.2020.2734}
}

@article{peskind2006-16861375,
  author  = {Peskind, E. R. and Potkin, S. G. and Pomara, N. and Ott, B. R. and Graham, S. M. and Olin, J. T. and McDonald, S.},
  title   = {{Memantine treatment in mild to moderate Alzheimer disease: a 24-week randomized, controlled trial}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2006},
  doi     = {10.1097/01.jgp.0000224350.82719.83},
  pmid    = {16861375},
  url     = {https://doi.org/10.1097/01.jgp.0000224350.82719.83}
}

@article{baker2025-40271888,
  author  = {Baker, L. D. and Pa, J. A. and Katula, J. A. and Aslanyan, V. and Salmon, D. P. and Jacobs, D. M. and Chmelo, E. A. and Hodge, H. and Morrison, R. and Matthews, G. and others},
  title   = {{Effects of exercise on cognition and Alzheimer's biomarkers in a randomized controlled trial of adults with mild cognitive impairment: The EXERT study}},
  journal = {Alzheimer's \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.14586},
  pmid    = {40271888},
  url     = {https://doi.org/10.1002/alz.14586}
}

@article{naj2014-25199842,
  author  = {Naj, A. C. and Jun, G. and Reitz, C. and Kunkle, B. W. and Perry, W. and Park, Y. S. and Beecham, G. W. and Rajbhandary, R. A. and others},
  title   = {{Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study}},
  journal = {JAMA neurology},
  year    = {2014},
  doi     = {10.1001/jamaneurol.2014.1491},
  pmid    = {25199842},
  url     = {https://doi.org/10.1001/jamaneurol.2014.1491}
}

@article{galasko2012-22431837,
  author  = {Galasko, D. R. and Peskind, E. and Clark, C. M. and Quinn, J. F. and Ringman, J. M. and Jicha, G. A. and Cotman, C. and Cottrell, B. and others},
  title   = {{Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures}},
  journal = {Archives of neurology},
  year    = {2012},
  doi     = {10.1001/archneurol.2012.85},
  pmid    = {22431837},
  url     = {https://doi.org/10.1001/archneurol.2012.85}
}

@article{nelson2014-24770881,
  author  = {Nelson, P. T. and Estus, S. and Abner, E. L. and Parikh, I. and Malik, M. and Neltner, J. H. and Ighodaro, E. and Wang, W. X. and others},
  title   = {{ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology}},
  journal = {Acta neuropathologica},
  year    = {2014},
  doi     = {10.1007/s00401-014-1282-2},
  pmid    = {24770881},
  url     = {https://doi.org/10.1007/s00401-014-1282-2}
}

@article{grill2025-39671543,
  author  = {Grill, J. D. and Tam, S. and Thai, G. and Vides, B. and Pierce, A. L. and Green, K. and Gillen, D. L. and Teng, E. and others},
  title   = {{Phase 2A Proof-of-Concept Double-Blind, Randomized, Placebo-Controlled Trial of Nicotinamide in Early Alzheimer Disease}},
  journal = {Neurology},
  year    = {2025},
  doi     = {10.1212/wnl.0000000000210152},
  pmid    = {39671543},
  url     = {https://doi.org/10.1212/wnl.0000000000210152}
}

@article{kawas2015-26180144,
  author  = {Kawas, C. H. and Kim, R. C. and Sonnen, J. A. and Bullain, S. S. and Trieu, T. and Corrada, M. M.},
  title   = {{Multiple pathologies are common and related to dementia in the oldest-old: The 90+ Study}},
  journal = {Neurology},
  year    = {2015},
  doi     = {10.1212/wnl.0000000000001831},
  pmid    = {26180144},
  url     = {https://doi.org/10.1212/wnl.0000000000001831}
}

@article{ayton2015-25988319,
  author  = {Ayton, S. and Faux, N. G. and Bush, A. I. and {Alzheimer's Disease Neuroimaging Initiative}},
  title   = {{Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE}},
  journal = {Nature communications},
  year    = {2015},
  doi     = {10.1038/ncomms7760},
  pmid    = {25988319},
  url     = {https://doi.org/10.1038/ncomms7760}
}

@article{wisch2024-38631766,
  author  = {Wisch, J. K. and McKay, N. S. and Boerwinkle, A. H. and Kennedy, J. and Flores, S. and Handen, B. L. and Christian, B. T. and Head, E. and others},
  title   = {{Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study}},
  journal = {The Lancet. Neurology},
  year    = {2024},
  doi     = {10.1016/s1474-4422(24)00084-x},
  pmid    = {38631766},
  url     = {https://doi.org/10.1016/s1474-4422(24)00084-x}
}

@article{mulnard2000-10697060,
  author  = {Mulnard, R. A. and Cotman, C. W. and Kawas, C. and van Dyck, C. H. and Sano, M. and Doody, R. and Koss, E. and Pfeiffer, E. and others},
  title   = {{Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: a randomized controlled trial. Alzheimer's Disease Cooperative Study}},
  journal = {JAMA},
  year    = {2000},
  doi     = {10.1001/jama.283.8.1007},
  pmid    = {10697060},
  url     = {https://doi.org/10.1001/jama.283.8.1007}
}

@article{nelson2019-31039256,
  author  = {Nelson, P. T. and Dickson, D. W. and Trojanowski, J. Q. and Jack, C. R. and Boyle, P. A. and Arfanakis, K. and Rademakers, R. and Alafuzoff, I. and others},
  title   = {{Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report}},
  journal = {Brain : a journal of neurology},
  year    = {2019},
  doi     = {10.1093/brain/awz099},
  pmid    = {31039256},
  url     = {https://doi.org/10.1093/brain/awz099}
}

@article{cholerton2018-29478836,
  author  = {Cholerton, B. and Johnson, C. O. and Fish, B. and Quinn, J. F. and Chung, K. A. and Peterson-Hiller, A. L. and Rosenthal, L. S. and Dawson, T. M. and others},
  title   = {{Sex differences in progression to mild cognitive impairment and dementia in Parkinson's disease}},
  journal = {Parkinsonism \& related disorders},
  year    = {2018},
  doi     = {10.1016/j.parkreldis.2018.02.007},
  pmid    = {29478836},
  url     = {https://doi.org/10.1016/j.parkreldis.2018.02.007}
}

@article{clare2010-20808145,
  author  = {Clare, L. and Linden, D. E. and Woods, R. T. and Whitaker, R. and Evans, S. J. and Parkinson, C. H. and van Paasschen, J. and Nelis, S. M. and others},
  title   = {{Goal-oriented cognitive rehabilitation for people with early-stage Alzheimer disease: a single-blind randomized controlled trial of clinical efficacy}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2010},
  doi     = {10.1097/jgp.0b013e3181d5792a},
  pmid    = {20808145},
  url     = {https://doi.org/10.1097/jgp.0b013e3181d5792a}
}

@article{lopez2003-14568809,
  author  = {Lopez, O. L. and Jagust, W. J. and Dulberg, C. and Becker, J. T. and DeKosky, S. T. and Fitzpatrick, A. and Breitner, J. and Lyketsos, C. and others},
  title   = {{Risk factors for mild cognitive impairment in the Cardiovascular Health Study Cognition Study: part 2}},
  journal = {Archives of neurology},
  year    = {2003},
  doi     = {10.1001/archneur.60.10.1394},
  pmid    = {14568809},
  url     = {https://doi.org/10.1001/archneur.60.10.1394}
}

@article{vandeerlin2010-20154673,
  author  = {Van Deerlin, V. M. and Sleiman, P. M. and Martinez-Lage, M. and Chen-Plotkin, A. and Wang, L. S. and Graff-Radford, N. R. and Dickson, D. W. and Rademakers, R. and others},
  title   = {{Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions}},
  journal = {Nature genetics},
  year    = {2010},
  doi     = {10.1038/ng.536},
  pmid    = {20154673},
  url     = {https://doi.org/10.1038/ng.536}
}

@article{davis2016-27571329,
  author  = {Davis, M. Y. and Johnson, C. O. and Leverenz, J. B. and Weintraub, D. and Trojanowski, J. Q. and Chen-Plotkin, A. and Van Deerlin, V. M. and Quinn, J. F. and others},
  title   = {{Association of GBA Mutations and the E326K Polymorphism With Motor and Cognitive Progression in Parkinson Disease}},
  journal = {JAMA neurology},
  year    = {2016},
  doi     = {10.1001/jamaneurol.2016.2245},
  pmid    = {27571329},
  url     = {https://doi.org/10.1001/jamaneurol.2016.2245}
}

@article{lee2019-30760848,
  author  = {Lee, G. and Nho, K. and Kang, B. and Sohn, K. A. and Kim, D. and {for Alzheimer’s Disease Neuroimaging Initiative}},
  title   = {{Predicting Alzheimer's disease progression using multi-modal deep learning approach}},
  journal = {Scientific reports},
  year    = {2019},
  doi     = {10.1038/s41598-018-37769-z},
  pmid    = {30760848},
  url     = {https://doi.org/10.1038/s41598-018-37769-z}
}

@article{grober2008-18282324,
  author  = {Grober, E. and Hall, C. B. and Lipton, R. B. and Zonderman, A. B. and Resnick, S. M. and Kawas, C.},
  title   = {{Memory impairment, executive dysfunction, and intellectual decline in preclinical Alzheimer's disease}},
  journal = {Journal of the International Neuropsychological Society : JINS},
  year    = {2008},
  doi     = {10.1017/s1355617708080302},
  pmid    = {18282324},
  url     = {https://doi.org/10.1017/s1355617708080302}
}

@article{janelidze2022-35789365,
  author  = {Janelidze, S. and Christian, B. T. and Price, J. and Laymon, C. and Schupf, N. and Klunk, W. E. and Lott, I. and Silverman, W. and others},
  title   = {{Detection of Brain Tau Pathology in Down Syndrome Using Plasma Biomarkers}},
  journal = {JAMA neurology},
  year    = {2022},
  doi     = {10.1001/jamaneurol.2022.1740},
  pmid    = {35789365},
  url     = {https://doi.org/10.1001/jamaneurol.2022.1740}
}

@article{lott2011-21739598,
  author  = {Lott, I. T. and Doran, E. and Nguyen, V. Q. and Tournay, A. and Head, E. and Gillen, D. L.},
  title   = {{Down syndrome and dementia: a randomized, controlled trial of antioxidant supplementation}},
  journal = {American journal of medical genetics. Part A},
  year    = {2011},
  doi     = {10.1002/ajmg.a.34114},
  pmid    = {21739598},
  url     = {https://doi.org/10.1002/ajmg.a.34114}
}

@article{vanderlip2026-41653883,
  author  = {Vanderlip, C. R. and Gillen, D. L. and Grill, J. D. and Stark, C. E. L.},
  title   = {{Digital memory assessments and plasma pTau217 enable efficient preclinical Alzheimer's trials}},
  journal = {The journal of prevention of Alzheimer's disease},
  year    = {2026},
  doi     = {10.1016/j.tjpad.2026.100503},
  pmid    = {41653883},
  url     = {https://doi.org/10.1016/j.tjpad.2026.100503}
}

@article{brown2022-35197628,
  author  = {Brown, A. L. and Wilkins, O. G. and Keuss, M. J. and Kargbo-Hill, S. E. and Zanovello, M. and Lee, W. C. and Bampton, A. and Lee, F. C. Y. and others},
  title   = {{TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A}},
  journal = {Nature},
  year    = {2022},
  doi     = {10.1038/s41586-022-04436-3},
  pmid    = {35197628},
  url     = {https://doi.org/10.1038/s41586-022-04436-3}
}

@article{chia2021-33589841,
  author  = {Chia, R. and Sabir, M. S. and Bandres-Ciga, S. and Saez-Atienzar, S. and Reynolds, R. H. and Gustavsson, E. and Walton, R. L. and Ahmed, S. and others},
  title   = {{Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture}},
  journal = {Nature genetics},
  year    = {2021},
  doi     = {10.1038/s41588-021-00785-3},
  pmid    = {33589841},
  url     = {https://doi.org/10.1038/s41588-021-00785-3}
}

@article{langbaum2025-41319675,
  author  = {Langbaum, J. B. and Bradbury, A. R. and Egleston, B. L. and McCarty Wood, E. and Langlois, C. M. and Largent, E. A. and Harkins, K. and Erickson, C. M. and Stites, S. D. and Oyen, E. and others},
  title   = {{Impact of learning APOE genotype on cognitively unimpaired adults: a pre-screening cohort study of the Alzheimer's Prevention Initiative Generation Study 1}},
  journal = {The Lancet Healthy Longevity},
  year    = {2025},
  doi     = {10.1016/j.lanhl.2025.100778},
  pmid    = {41319675},
  url     = {https://doi.org/10.1016/j.lanhl.2025.100778}
}

@article{sprecher2017-28679595,
  author  = {Sprecher, K. E. and Koscik, R. L. and Carlsson, C. M. and Zetterberg, H. and Blennow, K. and Okonkwo, O. C. and Sager, M. A. and Asthana, S. and others},
  title   = {{Poor sleep is associated with CSF biomarkers of amyloid pathology in cognitively normal adults}},
  journal = {Neurology},
  year    = {2017},
  doi     = {10.1212/wnl.0000000000004171},
  pmid    = {28679595},
  url     = {https://doi.org/10.1212/wnl.0000000000004171}
}

@article{grill2024-37830926,
  author  = {Grill, J. D. and Flournoy, C. and Dhadda, S. and Ernstrom, K. and Sperling, R. and Molina-Henry, D. and Tranotti, K. and Harris, R. and others},
  title   = {{Eligibility Rates among Racially and Ethnically Diverse US Participants in Phase 2 and Phase 3 Placebo-Controlled, Double-Blind, Randomized Trials of Lecanemab and Elenbecestat in Early Alzheimer Disease}},
  journal = {Annals of neurology},
  year    = {2024},
  doi     = {10.1002/ana.26819},
  pmid    = {37830926},
  url     = {https://doi.org/10.1002/ana.26819}
}

@article{corrada2010-20186856,
  author  = {Corrada, M. M. and Brookmeyer, R. and Paganini-Hill, A. and Berlau, D. and Kawas, C. H.},
  title   = {{Dementia incidence continues to increase with age in the oldest old: the 90+ study}},
  journal = {Annals of neurology},
  year    = {2010},
  doi     = {10.1002/ana.21915},
  pmid    = {20186856},
  url     = {https://doi.org/10.1002/ana.21915}
}

@article{mclachlan2024-c829b099,
  author  = {McLachlan, M. and Bettcher, B. and McVea, A. and DiFillipo, A. and Zammit, M. and LeMerise, L. and Rouanet, J. and Price, J. and others},
  title   = {{The striatum is an early, accurate indicator of amyloid burden using [11C]PiB in Down syndrome: comparison of two radiotracers}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2024},
  doi     = {10.1101/2024.12.04.24318526},
  url     = {https://doi.org/10.1101/2024.12.04.24318526}
}

@article{grill2026-41910973,
  author  = {Grill, Joshua D. and RAMAN, REMA and Wang, Shunran and Ernstrom, Karin B. and Andrews, Patricia and Appleby, Brian Stephen and Bhangu, Jaspreet S. and Dhadda, Shobha and others},
  title   = {{Amyloid Imaging and APOE Genotype Disclosure and Short-Term Psychological Distress}},
  journal = {JAMA Network Open},
  year    = {2026},
  doi     = {10.1001/jamanetworkopen.2026.3845},
  pmid    = {41910973},
  url     = {https://doi.org/10.1001/jamanetworkopen.2026.3845}
}

@article{oddo2003-12895417,
  author  = {Oddo, Salvatore and Caccamo, Antonella and Shepherd, Jason D. and Murphy, Michael Paul and Golde, Todd Eliot and Kayed, Rakez and Metherate, Raju and Mattson, Mark P. and others},
  title   = {{Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles}},
  journal = {Neuron},
  year    = {2003},
  doi     = {10.1016/s0896-6273(03)00434-3},
  pmid    = {12895417},
  url     = {https://doi.org/10.1016/s0896-6273(03)00434-3}
}

@article{fagan2021-34302786,
  author  = {Fagan, A. M. and Henson, R. L. and Li, Y. and Boerwinkle, A. H. and Xiong, C. and Bateman, R. J. and Goate, A. and Ances, B. M. and others},
  title   = {{Comparison of CSF biomarkers in Down syndrome and autosomal dominant Alzheimer's disease: a cross-sectional study}},
  journal = {The Lancet. Neurology},
  year    = {2021},
  doi     = {10.1016/s1474-4422(21)00139-3},
  pmid    = {34302786},
  url     = {https://doi.org/10.1016/s1474-4422(21)00139-3}
}

@article{reiman2020-32015339,
  author  = {Reiman, E. M. and Arboleda-Velasquez, J. F. and Quiroz, Y. T. and Huentelman, M. J. and Beach, T. G. and Caselli, R. J. and Chen, Y. and Su, Y. and others},
  title   = {{Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study}},
  journal = {Nature communications},
  year    = {2020},
  doi     = {10.1038/s41467-019-14279-8},
  pmid    = {32015339},
  url     = {https://doi.org/10.1038/s41467-019-14279-8}
}

@article{mckhann2011-21514250,
  author  = {McKhann, G. M. and Knopman, D. S. and Chertkow, H. and Hyman, B. T. and Jack, C. R. and Kawas, C. H. and Klunk, W. E. and Koroshetz, W. J. and others},
  title   = {{The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2011},
  doi     = {10.1016/j.jalz.2011.03.005},
  pmid    = {21514250},
  url     = {https://doi.org/10.1016/j.jalz.2011.03.005}
}

@article{sano1997-9110909,
  author  = {Sano, Mary and Ernesto, Christopher and Thomas, Ronald G. and Klauber, Melville R. and Schafer, Kimberly A and Grundman, Michael and Woodbury, Peter and Growdon, John H. and Cotman, Carl W. and Pfeiffer, Eric A. and Schneider, Lon S. and Thal, Leon J.},
  title   = {{A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study}},
  journal = {New England Journal of Medicine},
  year    = {1997},
  doi     = {10.1056/nejm199704243361704},
  pmid    = {9110909},
  url     = {https://doi.org/10.1056/nejm199704243361704}
}

@article{boerwinkle2023-36517172,
  author  = {Boerwinkle, A. H. and Gordon, B. A. and Wisch, J. and Flores, S. and Henson, R. L. and Butt, O. H. and McKay, N. and Chen, C. D. and others},
  title   = {{Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study}},
  journal = {The Lancet. Neurology},
  year    = {2023},
  doi     = {10.1016/s1474-4422(22)00408-2},
  pmid    = {36517172},
  url     = {https://doi.org/10.1016/s1474-4422(22)00408-2}
}

@article{lo2012-22972646,
  author  = {Lo, R. Y. and Jagust, W. J. and {Alzheimer's Disease Neuroimaging Initiative}},
  title   = {{Vascular burden and Alzheimer disease pathologic progression}},
  journal = {Neurology},
  year    = {2012},
  doi     = {10.1212/wnl.0b013e31826c1b9d},
  pmid    = {22972646},
  url     = {https://doi.org/10.1212/wnl.0b013e31826c1b9d}
}

@article{lopez2003-14568808,
  author  = {Lopez, O. L. and Jagust, W. J. and DeKosky, S. T. and Becker, J. T. and Fitzpatrick, A. and Dulberg, C. and Breitner, J. and Lyketsos, C. and others},
  title   = {{Prevalence and classification of mild cognitive impairment in the Cardiovascular Health Study Cognition Study: part 1}},
  journal = {Archives of neurology},
  year    = {2003},
  doi     = {10.1001/archneur.60.10.1385},
  pmid    = {14568808},
  url     = {https://doi.org/10.1001/archneur.60.10.1385}
}

@article{lott2019-30733618,
  author  = {Lott, I. T. and Head, E.},
  title   = {{Dementia in Down syndrome: unique insights for Alzheimer disease research}},
  journal = {Nature reviews. Neurology},
  year    = {2019},
  doi     = {10.1038/s41582-018-0132-6},
  pmid    = {30733618},
  url     = {https://doi.org/10.1038/s41582-018-0132-6}
}

@article{mclachlan2025-40189783,
  author  = {McLachlan, M. and Bettcher, B. and McVea, A. and DiFilippo, A. and Zammit, M. and LeMerise, L. and Rouanet, J. and Price, J. and others},
  title   = {{The striatum is an early, accurate indicator of amyloid burden using [11C]PiB in Down syndrome: Comparison of two radiotracers}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2025},
  doi     = {10.1002/alz.70141},
  pmid    = {40189783},
  url     = {https://doi.org/10.1002/alz.70141}
}

@article{kimura2025-40205047,
  author  = {Kimura, K. and Subramanian, A. and Yin, Z. and Khalilnezhad, A. and Wu, Y. and He, D. and Dixon, K. O. and Chitta, U. K. and Ding, X. and Adhikari, N. and Guzchenko, I. and Zhang, X. and others},
  title   = {{Immune checkpoint TIM-3 regulates microglia and Alzheimer's disease}},
  journal = {Nature},
  year    = {2025},
  doi     = {10.1038/s41586-025-08852-z},
  pmid    = {40205047},
  url     = {https://doi.org/10.1038/s41586-025-08852-z}
}

@article{fortea2021-34687637,
  author  = {Fortea, J. and Zaman, S. H. and Hartley, S. and Rafii, M. S. and Head, E. and Carmona-Iragui, M.},
  title   = {{Alzheimer's disease associated with Down syndrome: a genetic form of dementia}},
  journal = {The Lancet. Neurology},
  year    = {2021},
  doi     = {10.1016/s1474-4422(21)00245-3},
  pmid    = {34687637},
  url     = {https://doi.org/10.1016/s1474-4422(21)00245-3}
}

@article{wisch2026-41205623,
  author  = {Wisch, J. K. and Jiao, Z. and Kennedy, J. T. and Cohen, A. D. and Schlachetzki, Z. and Petersen, M. and Handen, B. L. and Christian, B. T. and others},
  title   = {{Imaging and plasma biomarkers for pathological accumulation in Down syndrome}},
  journal = {Brain : a journal of neurology},
  year    = {2026},
  doi     = {10.1093/brain/awaf418},
  pmid    = {41205623},
  url     = {https://doi.org/10.1093/brain/awaf418}
}

@article{heneka2025-39653749,
  author  = {Heneka, M. T. and van der Flier, W. M. and Jessen, F. and Hoozemanns, J. and Thal, D. R. and Boche, D. and Brosseron, F. and Teunissen, C. and others},
  title   = {{Neuroinflammation in Alzheimer disease}},
  journal = {Nature reviews. Immunology},
  year    = {2025},
  doi     = {10.1038/s41577-024-01104-7},
  pmid    = {39653749},
  url     = {https://doi.org/10.1038/s41577-024-01104-7}
}

@article{querfurth2010-20107219,
  author  = {Querfurth, Henry W. and LaFerla, Frank M.},
  title   = {{Alzheimer's Disease}},
  journal = {New England Journal of Medicine},
  year    = {2010},
  doi     = {10.1056/nejmra0909142},
  pmid    = {20107219},
  url     = {https://doi.org/10.1056/nejmra0909142}
}

@article{ghanbarian2025-41268784,
  author  = {Ghanbarian, E. and Qian, T. and Khorsand, B. and Zheng, L. and Sajjadi, S. A. and Grill, J. D. and Rabin, L. A. and Lipton, R. B. and Sperling, R. A. and Ezzati, A.},
  title   = {{Prognostic value of plasma glial fibrillary acidic protein in cognitively unimpaired older adults: Results from the A4 study}},
  journal = {Alzheimer's \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70948},
  pmid    = {41268784},
  url     = {https://doi.org/10.1002/alz.70948}
}

@article{mapstone2014-24608097,
  author  = {Mapstone, M. and Cheema, A. K. and Fiandaca, M. S. and Zhong, X. and Mhyre, T. R. and MacArthur, L. H. and Hall, W. J. and Fisher, S. G. and others},
  title   = {{Plasma phospholipids identify antecedent memory impairment in older adults}},
  journal = {Nature medicine},
  year    = {2014},
  doi     = {10.1038/nm.3466},
  pmid    = {24608097},
  url     = {https://doi.org/10.1038/nm.3466}
}

@article{lao2020-32944999,
  author  = {Lao, P. J. and Gutierrez, J. and Keator, D. and Rizvi, B. and Banerjee, A. and Igwe, K. C. and Laing, K. K. and Sathishkumar, M. and others},
  title   = {{Alzheimer-Related Cerebrovascular Disease in Down Syndrome}},
  journal = {Annals of neurology},
  year    = {2020},
  doi     = {10.1002/ana.25905},
  pmid    = {32944999},
  url     = {https://doi.org/10.1002/ana.25905}
}

@article{mata2014-25178429,
  author  = {Mata, I. F. and Leverenz, J. B. and Weintraub, D. and Trojanowski, J. Q. and Hurtig, H. I. and Van Deerlin, V. M. and Ritz, B. and Rausch, R. and others},
  title   = {{APOE, MAPT, and SNCA genes and cognitive performance in Parkinson disease}},
  journal = {JAMA neurology},
  year    = {2014},
  doi     = {10.1001/jamaneurol.2014.1455},
  pmid    = {25178429},
  url     = {https://doi.org/10.1001/jamaneurol.2014.1455}
}

@article{koronyo2023-36773106,
  author  = {Koronyo, Y. and Rentsendorj, A. and Mirzaei, N. and Regis, G. C. and Sheyn, J. and Shi, H. and Barron, E. and Cook-Wiens, G. and others},
  title   = {{Retinal pathological features and proteome signatures of Alzheimer's disease}},
  journal = {Acta neuropathologica},
  year    = {2023},
  doi     = {10.1007/s00401-023-02548-2},
  pmid    = {36773106},
  url     = {https://doi.org/10.1007/s00401-023-02548-2}
}

@article{sible2022-35418462,
  author  = {Sible, I. J. and Nation, D. A. and {Alzheimer's Disease Neuroimaging Initiative}},
  title   = {{Visit-to-Visit Blood Pressure Variability and CSF Alzheimer Disease Biomarkers in Cognitively Unimpaired and Mildly Impaired Older Adults}},
  journal = {Neurology},
  year    = {2022},
  doi     = {10.1212/wnl.0000000000200302},
  pmid    = {35418462},
  url     = {https://doi.org/10.1212/wnl.0000000000200302}
}

@article{marquez2025-40911305,
  author  = {Márquez, F. and Tarraf, W. and Gonzalez, K. and Valencia, D. F. and Stickel, A. M. and Anita, N. Z. and Sotres-Alvarez, D. and Levin, B. E. and others},
  title   = {{Alzheimer Disease Biomarkers and Subjective Cognitive Decline Among Hispanic and/or Latino Adults}},
  journal = {JAMA network open},
  year    = {2025},
  doi     = {10.1001/jamanetworkopen.2025.31038},
  pmid    = {40911305},
  url     = {https://doi.org/10.1001/jamanetworkopen.2025.31038}
}

@article{li2026-41535386,
  author  = {Li, Jun and Hu, Jie and Yun, Huan and Mei, Zhendong and Wang, Xingyan and Luo, Kai and Guasch‐Ferré, Marta and Han, Xikun and others},
  title   = {{Circulating metabolites, genetics and lifestyle factors in relation to future risk of type 2 diabetes}},
  journal = {Nature Medicine},
  year    = {2026},
  doi     = {10.1038/s41591-025-04105-8},
  pmid    = {41535386},
  url     = {https://doi.org/10.1038/s41591-025-04105-8}
}

@article{fleck2025-39786167,
  author  = {Fleck, Lara and Buß, Claudia and Bauer, M. and Stein, Maike and Mekle, Ralf and Kock, Lena and Klawitter, Heiko and Godara, Malvika and others},
  title   = {{Early‐Life Adversity Predicts Markers of Aging‐Related Neuroinflammation, Neurodegeneration, and Cognitive Impairment in Women}},
  journal = {Annals of Neurology},
  year    = {2025},
  doi     = {10.1002/ana.27161},
  pmid    = {39786167},
  url     = {https://doi.org/10.1002/ana.27161}
}

@article{grill2024-38585443,
  author  = {Grill, J. D. and Raman, R. and Ernstrom, K. and Wang, S. and Donohue, M. C. and Aisen, P. S. and Karlawish, J. and Henley, D. and others},
  title   = {{Immediate Reactions to Alzheimer Biomarker Disclosure in Cognitively Unimpaired Individuals in a Global Truncated Randomized Trial}},
  journal = {Neurology. Clinical practice},
  year    = {2024},
  doi     = {10.1212/cpj.0000000000200265},
  pmid    = {38585443},
  url     = {https://doi.org/10.1212/cpj.0000000000200265}
}

@article{zammit2026-41240365,
  author  = {Zammit, M. D. and Bruzzone, H. and Cody, K. A. and Morse, J. and Wilson, R. and Bettcher, B. T. and McLachlan, M. J. and McVea, A. K. and others},
  title   = {{The tau biomarker cascade is condensed in Down syndrome compared with sporadic Alzheimer's disease}},
  journal = {Brain : a journal of neurology},
  year    = {2026},
  doi     = {10.1093/brain/awaf428},
  pmid    = {41240365},
  url     = {https://doi.org/10.1093/brain/awaf428}
}

@article{xicota2024-39500037,
  author  = {Xicota, L. and Dang, L. T. and Lee, A. and Krinsky-McHale, S. and Pang, D. and Melilli, L. and O'Bryant, S. and Henson, R. L. and others},
  title   = {{The effects of mosaicism on biological and clinical markers of Alzheimer's disease in adults with Down syndrome}},
  journal = {EBioMedicine},
  year    = {2024},
  doi     = {10.1016/j.ebiom.2024.105433},
  pmid    = {39500037},
  url     = {https://doi.org/10.1016/j.ebiom.2024.105433}
}

@article{chung2026-42096659,
  author  = {Chung, P. A. and Fleming, V. L. and Reid, K. J. and Plante, D. T. and Hom, C. L. and Ances, B. M. and Handen, B. L. and Christian, B. T. and others},
  title   = {{Circadian Rest-Activity Rhythms, Cognition, and Alzheimer Disease Dementia in Adults With Down Syndrome}},
  journal = {Neurology},
  year    = {2026},
  doi     = {10.1212/wnl.0000000000214938},
  pmid    = {42096659},
  url     = {https://doi.org/10.1212/wnl.0000000000214938}
}

@article{mcquade2020-33097708,
  author  = {McQuade, A. and Kang, Y. J. and Hasselmann, J. and Jairaman, A. and Sotelo, A. and Coburn, M. and Shabestari, S. K. and Chadarevian, J. P. and others},
  title   = {{Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease}},
  journal = {Nature communications},
  year    = {2020},
  doi     = {10.1038/s41467-020-19227-5},
  pmid    = {33097708},
  url     = {https://doi.org/10.1038/s41467-020-19227-5}
}

@article{mata2016-26296077,
  author  = {Mata, I. F. and Leverenz, J. B. and Weintraub, D. and Trojanowski, J. Q. and Chen-Plotkin, A. and Van Deerlin, V. M. and Ritz, B. and Rausch, R. and others},
  title   = {{GBA Variants are associated with a distinct pattern of cognitive deficits in Parkinson's disease}},
  journal = {Movement disorders : official journal of the Movement Disorder Society},
  year    = {2016},
  doi     = {10.1002/mds.26359},
  pmid    = {26296077},
  url     = {https://doi.org/10.1002/mds.26359}
}

@article{brycesmith2025-41120751,
  author  = {Bryce-Smith, Sam and Brown, Anna‐Leigh and Chien, Max Z. Y. J. and Dattilo, Dario and Mehta, Puja R. and Mattedi, Francesca and Barattucci, Simone and Mikheenko, Alla and others},
  title   = {{TDP-43 loss induces cryptic polyadenylation in ALS/FTD}},
  journal = {Nature Neuroscience},
  year    = {2025},
  doi     = {10.1038/s41593-025-02050-w},
  pmid    = {41120751},
  url     = {https://doi.org/10.1038/s41593-025-02050-w}
}

@article{woodworth2025-40323260,
  author  = {Woodworth, Davis C. and Lou, Jicheng and Yong, William H. and Head, Elizabeth and Corrada, María M. and Nelson, Peter T. and Sajjadi, S. Ahmad},
  title   = {{Common neuropathologic change drivers of hippocampal sclerosis of ageing}},
  journal = {Brain},
  year    = {2025},
  doi     = {10.1093/brain/awaf158},
  pmid    = {40323260},
  url     = {https://doi.org/10.1093/brain/awaf158}
}

@article{colbeth2026-42551464,
  author  = {Colbeth, Hilary L and Corrada, Maria M and Mungas, Dan and Gilsanz, Paola and George, Kristen M and Gaied, Reham and Kawas, Claudia H and DeCarli, Charles and others},
  title   = {{Incidence of dementia after age 90 years and association with APOE genotype, race, and sex in the USA: the LifeAfter90 prospective cohort study}},
  journal = {The lancet. Healthy longevity},
  year    = {2026},
  doi     = {10.1016/j.lanhl.2026.100882},
  pmid    = {42551464},
  url     = {https://doi.org/10.1016/j.lanhl.2026.100882}
}

@article{seshadri2011-21255742,
  author  = {Seshadri, S. and Beiser, A. and Au, R. and Wolf, P. A. and Evans, D. A. and Wilson, R. S. and Petersen, R. C. and Knopman, D. S. and others},
  title   = {{Operationalizing diagnostic criteria for Alzheimer's disease and other age-related cognitive impairment-Part 2}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2011},
  doi     = {10.1016/j.jalz.2010.12.002},
  pmid    = {21255742},
  url     = {https://doi.org/10.1016/j.jalz.2010.12.002}
}

@article{kuller2005-15883315,
  author  = {Kuller, L. H. and Lopez, O. L. and Jagust, W. J. and Becker, J. T. and DeKosky, S. T. and Lyketsos, C. and Kawas, C. and Breitner, J. C. and others},
  title   = {{Determinants of vascular dementia in the Cardiovascular Health Cognition Study}},
  journal = {Neurology},
  year    = {2005},
  doi     = {10.1212/01.wnl.0000160115.55756.de},
  pmid    = {15883315},
  url     = {https://doi.org/10.1212/01.wnl.0000160115.55756.de}
}

@article{forseth2018-29860298,
  author  = {Forseth, K. J. and Kadipasaoglu, C. M. and Conner, C. R. and Hickok, G. and Knight, R. T. and Tandon, N.},
  title   = {{A lexical semantic hub for heteromodal naming in middle fusiform gyrus}},
  journal = {Brain : a journal of neurology},
  year    = {2018},
  doi     = {10.1093/brain/awy120},
  pmid    = {29860298},
  url     = {https://doi.org/10.1093/brain/awy120}
}

@article{cummings1995-7491048,
  author  = {Cummings, B. J. and Cotman, C. W.},
  title   = {{Image analysis of beta-amyloid load in Alzheimer's disease and relation to dementia severity}},
  journal = {Lancet (London, England)},
  year    = {1995},
  doi     = {10.1016/s0140-6736(95)92053-6},
  pmid    = {7491048},
  url     = {https://doi.org/10.1016/s0140-6736(95)92053-6}
}

@article{zhu2024-38397619,
  author  = {Zhu, Yachen and Shi, Yuxi Vania and Bartell, Scott M. and Corrada, María M. and Manson, Spero M. and O’Connell, Joan M. and Jiang, Luohua},
  title   = {{Potential Effects of Long-Term Exposure to Air Pollution on Dementia: A Longitudinal Analysis in American Indians Aged 55 Years and Older}},
  journal = {International Journal of Environmental Research and Public Health},
  year    = {2024},
  doi     = {10.3390/ijerph21020128},
  pmid    = {38397619},
  url     = {https://doi.org/10.3390/ijerph21020128}
}

@article{lott2010-20494326,
  author  = {Lott, I. T. and Dierssen, M.},
  title   = {{Cognitive deficits and associated neurological complications in individuals with Down's syndrome}},
  journal = {The Lancet. Neurology},
  year    = {2010},
  doi     = {10.1016/s1474-4422(10)70112-5},
  pmid    = {20494326},
  url     = {https://doi.org/10.1016/s1474-4422(10)70112-5}
}

@article{quiroz2022-35199931,
  author  = {Quiroz, Y. T. and Solis, M. and Aranda, M. P. and Arbaje, A. I. and Arroyo-Miranda, M. and Cabrera, L. Y. and Carrasquillo, M. M. and Corrada, M. M. and others},
  title   = {{Addressing the disparities in dementia risk, early detection and care in Latino populations: Highlights from the second Latinos \& Alzheimer's Symposium}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2022},
  doi     = {10.1002/alz.12589},
  pmid    = {35199931},
  url     = {https://doi.org/10.1002/alz.12589}
}

@article{liu2024-39158850,
  author  = {Liu, L. and Saba, A. and Pascual, JR. and Miller, M. B. and Hennessey, E. L. and Lott, I. T. and Brickman, A. M. and Wilcock, D. M. and others},
  title   = {{Lecanemab and Vascular-Amyloid Deposition in Brains of People With Down Syndrome}},
  journal = {JAMA neurology},
  year    = {2024},
  doi     = {10.1001/jamaneurol.2024.2579},
  pmid    = {39158850},
  url     = {https://doi.org/10.1001/jamaneurol.2024.2579}
}

@article{clinton2010-20505094,
  author  = {Clinton, L. K. and Blurton-Jones, M. and Myczek, K. and Trojanowski, J. Q. and LaFerla, F. M.},
  title   = {{Synergistic Interactions between Abeta, tau, and alpha-synuclein: acceleration of neuropathology and cognitive decline}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2010},
  doi     = {10.1523/jneurosci.0490-10.2010},
  pmid    = {20505094},
  url     = {https://doi.org/10.1523/jneurosci.0490-10.2010}
}

@article{you2022-35029059,
  author  = {You, Y. and Muraoka, S. and Jedrychowski, M. P. and Hu, J. and McQuade, A. K. and Young-Pearse, T. and Aslebagh, R. and Shaffer, S. A. and others},
  title   = {{Human neural cell type-specific extracellular vesicle proteome defines disease-related molecules associated with activated astrocytes in Alzheimer's disease brain}},
  journal = {Journal of extracellular vesicles},
  year    = {2022},
  doi     = {10.1002/jev2.12183},
  pmid    = {35029059},
  url     = {https://doi.org/10.1002/jev2.12183}
}

@article{kianishabestari2022-35705056,
  author  = {Kiani Shabestari, S. and Morabito, S. and Danhash, E. P. and McQuade, A. and Sanchez, JR. and Miyoshi, E. and Chadarevian, J. P. and Claes, C. and others},
  title   = {{Absence of microglia promotes diverse pathologies and early lethality in Alzheimer's disease mice}},
  journal = {Cell reports},
  year    = {2022},
  doi     = {10.1016/j.celrep.2022.110961},
  pmid    = {35705056},
  url     = {https://doi.org/10.1016/j.celrep.2022.110961}
}

@article{cummings1996-9363804,
  author  = {Cummings, B. J. and Pike, C. J. and Shankle, R. and Cotman, C. W.},
  title   = {{Beta-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease}},
  journal = {Neurobiology of aging},
  year    = {1996},
  doi     = {10.1016/s0197-4580(96)00170-4},
  pmid    = {9363804},
  url     = {https://doi.org/10.1016/s0197-4580(96)00170-4}
}

@article{hsieh2009-19302484,
  author  = {Hsieh, C. L. and Koike, M. and Spusta, S. C. and Niemi, E. C. and Yenari, M. and Nakamura, M. C. and Seaman, W. E.},
  title   = {{A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia}},
  journal = {Journal of neurochemistry},
  year    = {2009},
  doi     = {10.1111/j.1471-4159.2009.06042.x},
  pmid    = {19302484},
  url     = {https://doi.org/10.1111/j.1471-4159.2009.06042.x}
}

@article{kapoor2025-39787444,
  author  = {Kapoor, Arunima and Dutt, Shubir and Engstrom, Allison C and Alitin, John Paul M and Lohman, Trevor and Sible, Isabel J. and Marshall, Anisa J. and Shenasa, Fatemah and others},
  title   = {{Association of Medial Temporal Lobe Cerebrovascular Reactivity and Memory Function in Older Adults With and Without Cognitive Impairment}},
  journal = {Neurology},
  year    = {2025},
  doi     = {10.1212/wnl.0000000000210210},
  pmid    = {39787444},
  url     = {https://doi.org/10.1212/wnl.0000000000210210}
}

@article{melikyan2025-40340138,
  author  = {Melikyan, Zarui A. and Aguirre, Colette and Al‐Darsani, Zeinah and Colcord, Katherine A. and Paganini‐Hill, Annlia and Farias, Sarah Tomaszewski and Jiang, Luohua and Kawas, Claudia H. and others},
  title   = {{Subjective memory complaints at age 90 + in relation to cognition and risk of incident dementia: The 90 + Study}},
  journal = {International Psychogeriatrics},
  year    = {2025},
  doi     = {10.1016/j.inpsyc.2025.100083},
  pmid    = {40340138},
  url     = {https://doi.org/10.1016/j.inpsyc.2025.100083}
}

@article{roach2025-41275266,
  author  = {Roach, Jared C. and Glusman, Gwênlyn and Rapozo, Molly K. and Merrill, David A. and Bramen, Jennifer E. and Hodes, John F. and Siddarth, Prabha and Meysami, Somayeh and others},
  title   = {{Multidomain therapy for Alzheimer’s disease: a scoping review of cognitive decline trials}},
  journal = {Molecular Neurodegeneration},
  year    = {2025},
  doi     = {10.1186/s13024-025-00912-2},
  pmid    = {41275266},
  url     = {https://doi.org/10.1186/s13024-025-00912-2}
}

@article{winchester2013-22959822,
  author  = {Winchester, J. and Dick, M. B. and Gillen, D. and Reed, B. and Miller, B. and Tinklenberg, J. and Mungas, D. and Chui, H. and others},
  title   = {{Walking stabilizes cognitive functioning in Alzheimer's disease (AD) across one year}},
  journal = {Archives of gerontology and geriatrics},
  year    = {2013},
  doi     = {10.1016/j.archger.2012.06.016},
  pmid    = {22959822},
  url     = {https://doi.org/10.1016/j.archger.2012.06.016}
}

@article{dishman2006-16648603,
  author  = {Dishman, R. K. and Berthoud, H. R. and Booth, F. W. and Cotman, C. W. and Edgerton, V. R. and Fleshner, M. R. and Gandevia, S. C. and Gomez-Pinilla, F. and others},
  title   = {{Neurobiology of exercise}},
  journal = {Obesity (Silver Spring, Md.)},
  year    = {2006},
  doi     = {10.1038/oby.2006.46},
  pmid    = {16648603},
  url     = {https://doi.org/10.1038/oby.2006.46}
}

@article{head2017-29195510,
  author  = {Head, E. and Phelan, M. J. and Doran, E. and Kim, R. C. and Poon, W. W. and Schmitt, F. A. and Lott, I. T.},
  title   = {{Cerebrovascular pathology in Down syndrome and Alzheimer disease}},
  journal = {Acta neuropathologica communications},
  year    = {2017},
  doi     = {10.1186/s40478-017-0499-4},
  pmid    = {29195510},
  url     = {https://doi.org/10.1186/s40478-017-0499-4}
}

@article{blurtonjones2009-19633196,
  author  = {Blurton-Jones, M. and Kitazawa, M. and Martinez-Coria, H. and Castello, N. A. and Müller, F. J. and Loring, J. F. and Yamasaki, T. R. and Poon, W. W. and others},
  title   = {{Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2009},
  doi     = {10.1073/pnas.0901402106},
  pmid    = {19633196},
  url     = {https://doi.org/10.1073/pnas.0901402106}
}

@article{cohen2013-23575824,
  author  = {Cohen, R. M. and Rezai-Zadeh, K. and Weitz, T. M. and Rentsendorj, A. and Gate, D. and Spivak, I. and Bholat, Y. and Vasilevko, V. and others},
  title   = {{A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal loss}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2013},
  doi     = {10.1523/jneurosci.3672-12.2013},
  pmid    = {23575824},
  url     = {https://doi.org/10.1523/jneurosci.3672-12.2013}
}

@article{hauremirande2017-28612290,
  author  = {Haure-Mirande, J. V. and Audrain, M. and Fanutza, T. and Kim, S. H. and Klein, W. L. and Glabe, C. and Readhead, B. and Dudley, J. T. and others},
  title   = {{Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer's pathology}},
  journal = {Acta neuropathologica},
  year    = {2017},
  doi     = {10.1007/s00401-017-1737-3},
  pmid    = {28612290},
  url     = {https://doi.org/10.1007/s00401-017-1737-3}
}

@article{singh2026-42162487,
  author  = {Singh, Alpana and Denkinger, Marisa N. and Leuzy, Antoine and Dieckhoff, Kari and Liu, Jame and Marques, Tainá M. and Monuki, Edwin S. and Stark, Craig and others},
  title   = {{A plasma protein signature for cerebral amyloid angiopathy}},
  journal = {Acta Neuropathologica},
  year    = {2026},
  doi     = {10.1007/s00401-026-03030-5},
  pmid    = {42162487},
  url     = {https://doi.org/10.1007/s00401-026-03030-5}
}

@article{arnold2025-40454469,
  author  = {Arnold, Frederick J. and Cui, Ya and Michels, Sebastian and Colwin, Michael R. and Stockford, Cameron M. and Ye, Wenbin and Bharathi, Vidhya and Jansen‐West, Karen R. and others},
  title   = {{TDP-43 dysregulation of polyadenylation site selection is a defining feature of RNA misprocessing in amyotrophic lateral sclerosis and frontotemporal dementia}},
  journal = {Journal of Clinical Investigation},
  year    = {2025},
  doi     = {10.1172/jci182088},
  pmid    = {40454469},
  url     = {https://doi.org/10.1172/jci182088}
}

@article{fried1991-1669507,
  author  = {Fried, Linda P. and Borhani, Nemat O. and Enright, Paul and Furberg, Curt Daniel and Gardin, Julius M. and Kronmal, Richard A. and Kuller, Lewis H. and Manolio, Teri A. and Mittelmark, Maurice B. and Newman, Anne B. and O’Leary, Daniel H. and Psaty, Bruce M. and Rautaharju, Pentti M. and Tracy, Russell P. and Weiler, Philip G.},
  title   = {{The cardiovascular health study: Design and rationale}},
  journal = {Annals of Epidemiology},
  year    = {1991},
  doi     = {10.1016/1047-2797(91)90005-w},
  pmid    = {1669507},
  url     = {https://doi.org/10.1016/1047-2797(91)90005-w}
}

@article{claes2021-34301296,
  author  = {Claes, C. and Danhash, E. P. and Hasselmann, J. and Chadarevian, J. P. and Shabestari, S. K. and England, W. E. and Lim, T. E. and Hidalgo, J. L. S. and others},
  title   = {{Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer's disease}},
  journal = {Molecular neurodegeneration},
  year    = {2021},
  doi     = {10.1186/s13024-021-00473-0},
  pmid    = {34301296},
  url     = {https://doi.org/10.1186/s13024-021-00473-0}
}

@article{berlau2009-19255410,
  author  = {Berlau, D. J. and Corrada, M. M. and Head, E. and Kawas, C. H.},
  title   = {{APOE epsilon2 is associated with intact cognition but increased Alzheimer pathology in the oldest old}},
  journal = {Neurology},
  year    = {2009},
  doi     = {10.1212/01.wnl.0000343853.00346.a4},
  pmid    = {19255410},
  url     = {https://doi.org/10.1212/01.wnl.0000343853.00346.a4}
}

@article{tai2013-23293020,
  author  = {Tai, L. M. and Bilousova, T. and Jungbauer, L. and Roeske, S. K. and Youmans, K. L. and Yu, C. and Poon, W. W. and Cornwell, L. B. and others},
  title   = {{Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples}},
  journal = {The Journal of biological chemistry},
  year    = {2013},
  doi     = {10.1074/jbc.m112.442103},
  pmid    = {23293020},
  url     = {https://doi.org/10.1074/jbc.m112.442103}
}

@article{montine2019-30857563,
  author  = {Montine, T. J. and Cholerton, B. A. and Corrada, M. M. and Edland, S. D. and Flanagan, M. E. and Hemmy, L. S. and Kawas, C. H. and White, L. R.},
  title   = {{Concepts for brain aging: resistance, resilience, reserve, and compensation}},
  journal = {Alzheimer's research \& therapy},
  year    = {2019},
  doi     = {10.1186/s13195-019-0479-y},
  pmid    = {30857563},
  url     = {https://doi.org/10.1186/s13195-019-0479-y}
}

@article{varatharajah2019-30783207,
  author  = {Varatharajah, Y. and Ramanan, V. K. and Iyer, R. and Vemuri, P. and {Alzheimer’s Disease Neuroimaging Initiative}},
  title   = {{Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics}},
  journal = {Scientific reports},
  year    = {2019},
  doi     = {10.1038/s41598-019-38793-3},
  pmid    = {30783207},
  url     = {https://doi.org/10.1038/s41598-019-38793-3}
}

@article{hokama2014-23595620,
  author  = {Hokama, M. and Oka, S. and Leon, J. and Ninomiya, T. and Honda, H. and Sasaki, K. and Iwaki, T. and Ohara, T. and others},
  title   = {{Altered expression of diabetes-related genes in Alzheimer's disease brains: the Hisayama study}},
  journal = {Cerebral cortex (New York, N.Y. : 1991)},
  year    = {2014},
  doi     = {10.1093/cercor/bht101},
  pmid    = {23595620},
  url     = {https://doi.org/10.1093/cercor/bht101}
}

@article{castillo2017-29259249,
  author  = {Castillo, E. and Leon, J. and Mazzei, G. and Abolhassani, N. and Haruyama, N. and Saito, T. and Saido, T. and Hokama, M. and others},
  title   = {{Comparative profiling of cortical gene expression in Alzheimer's disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation}},
  journal = {Scientific reports},
  year    = {2017},
  doi     = {10.1038/s41598-017-17999-3},
  pmid    = {29259249},
  url     = {https://doi.org/10.1038/s41598-017-17999-3}
}

@article{liu2020-32941599,
  author  = {Liu, T. and Zhu, B. and Liu, Y. and Zhang, X. and Yin, J. and Li, X. and Jiang, L. and Hodges, A. P. and others},
  title   = {{Multi-omic comparison of Alzheimer's variants in human ESC-derived microglia reveals convergence at APOE}},
  journal = {The Journal of experimental medicine},
  year    = {2020},
  doi     = {10.1084/jem.20200474},
  pmid    = {32941599},
  url     = {https://doi.org/10.1084/jem.20200474}
}

@article{rissman2004-15232619,
  author  = {Rissman, R. A. and Poon, W. W. and Blurton-Jones, M. and Oddo, S. and Torp, R. and Vitek, M. P. and LaFerla, F. M. and Rohn, T. T. and others},
  title   = {{Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology}},
  journal = {The Journal of clinical investigation},
  year    = {2004},
  doi     = {10.1172/jci20640},
  pmid    = {15232619},
  url     = {https://doi.org/10.1172/jci20640}
}

@article{hammond2025-41434365,
  author  = {Hammond, Angel and Navaratna, Ruvini and Moody, Jason F. and DeWitt, Amanda and Alosco, Michael Louis and Atri, Alireza and Bakulski, Kelly M. and Beach, Thomas G. and others},
  title   = {{Association of Neighborhood‐Level Disadvantage with Antemortem MRI Brain Volumes in a Multi‐site Brain Bank Donor Cohort}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70861_108929},
  pmid    = {41434365},
  url     = {https://doi.org/10.1002/alz70861_108929}
}

@article{pfeffer1982-7069156,
  author  = {PFEFFER, R. I. and Kurosaki, Takashi and Harrah, C. H. and Chance, J. M. and Filos, S.},
  title   = {{Measurement of Functional Activities in Older Adults in the Community}},
  journal = {Journal of Gerontology},
  year    = {1982},
  doi     = {10.1093/geronj/37.3.323},
  pmid    = {7069156},
  url     = {https://doi.org/10.1093/geronj/37.3.323}
}

@article{vanderlip2025-40491259,
  author  = {Vanderlip, C. R. and Stark, C. E. L.},
  title   = {{Integrating plasma p-tau217 and digital cognitive assessments for early detection in Alzheimer's disease}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2025},
  doi     = {10.1002/alz.70355},
  pmid    = {40491259},
  url     = {https://doi.org/10.1002/alz.70355}
}

@article{stern2023-cdf6b8dd,
  author  = {Stern, A. M. and Van Pelt, K. L. and Liu, L. and Anderson, A. K. and Ostaszewski, B. and Mapstone, M. and O’Bryant, S. and Petersen, M. E. and others},
  title   = {{Plasma NT1-tau and Aβ42correlate with age and cognitive function in two large Down syndrome cohorts}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2023},
  doi     = {10.1101/2023.03.10.23287109},
  url     = {https://doi.org/10.1101/2023.03.10.23287109}
}

@article{jairaman2022-35191835,
  author  = {Jairaman, A. and McQuade, A. and Granzotto, A. and Kang, Y. J. and Chadarevian, J. P. and Gandhi, S. and Parker, I. and Smith, I. and others},
  title   = {{TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia}},
  journal = {eLife},
  year    = {2022},
  doi     = {10.7554/elife.73021},
  pmid    = {35191835},
  url     = {https://doi.org/10.7554/elife.73021}
}

@article{neumann2007-17279000,
  author  = {Neumann, M. and Mackenzie, I. R. and Cairns, N. J. and Boyer, P. J. and Markesbery, W. R. and Smith, C. D. and Taylor, J. P. and Kretzschmar, H. A. and others},
  title   = {{TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations}},
  journal = {Journal of neuropathology and experimental neurology},
  year    = {2007},
  doi     = {10.1097/nen.0b013e31803020b9},
  pmid    = {17279000},
  url     = {https://doi.org/10.1097/nen.0b013e31803020b9}
}

@article{weihl2008-18796596,
  author  = {Weihl, C. C. and Temiz, P. and Miller, S. E. and Watts, G. and Smith, C. and Forman, M. and Hanson, P. I. and Kimonis, V. and others},
  title   = {{TDP-43 accumulation in inclusion body myopathy muscle suggests a common pathogenic mechanism with frontotemporal dementia}},
  journal = {Journal of neurology, neurosurgery, and psychiatry},
  year    = {2008},
  doi     = {10.1136/jnnp.2007.131334},
  pmid    = {18796596},
  url     = {https://doi.org/10.1136/jnnp.2007.131334}
}

@article{kim2025-40454424,
  author  = {Kim, Jeong Eun and Knox, Melissa L. and Grill, Joshua D. and Witbracht, Megan Gage and Zhang, Yuchen and Salazar, Hector and Garrett, Marita and Russ, Eunji and others},
  title   = {{Virtual Data Collection Strategies in Research on Alzheimer’s Disease and Related Dementias (ADRD)}},
  journal = {Innovation in Aging},
  year    = {2025},
  doi     = {10.1093/geroni/igaf026},
  pmid    = {40454424},
  url     = {https://doi.org/10.1093/geroni/igaf026}
}

@article{rosas2024-39583646,
  author  = {Rosas, H. D. and Mercaldo, N. D. and Hasimoglu, Y. and Petersen, M. and Lewis, L. R. and Lai, F. and Powell, D. and Dhungana, A. and others},
  title   = {{Association of plasma neurofilament light chain with microstructural white matter changes in Down syndrome}},
  journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)},
  year    = {2024},
  doi     = {10.1002/dad2.70023},
  pmid    = {39583646},
  url     = {https://doi.org/10.1002/dad2.70023}
}

@article{clina2026-41561734,
  author  = {Clina, J. G. and Helsel, B. C. and Hartley, S. L. and White, D. A. and Fleming-Batayneh, V. L. and Handen, B. and Christian, B. and Head, E. and others},
  title   = {{The impact of congenital heart disease on the timing of Alzheimer's disease in Down syndrome}},
  journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)},
  year    = {2026},
  doi     = {10.1002/dad2.70257},
  pmid    = {41561734},
  url     = {https://doi.org/10.1002/dad2.70257}
}

@article{pascual2026-41865347,
  author  = {Pascual, JR. and Rivera, I. and Nguyen, H. and Ngo, P. T. and Hoang, A. and Andrews, E. J. and Rouanet, J. and Wright, S. T. and others},
  title   = {{Neuropathological measures of increased tau phosphorylation across the Down syndrome lifespan}},
  journal = {Acta neuropathologica},
  year    = {2026},
  doi     = {10.1007/s00401-026-02994-8},
  pmid    = {41865347},
  url     = {https://doi.org/10.1007/s00401-026-02994-8}
}

@article{yoon2025-40794806,
  author  = {Yoon, D. M. and Plante, D. and Fleming, V. and Handen, B. and Lao, P. and Peven, J. and Christian, B. and Okonkwo, O. and others},
  title   = {{Preliminary Investigation of Obstructive Sleep Apnea and Alzheimer's Disease in Down Syndrome}},
  journal = {Sleep},
  year    = {2025},
  doi     = {10.1093/sleep/zpaf044},
  pmid    = {40794806},
  url     = {https://doi.org/10.1093/sleep/zpaf044}
}

@article{mcquade2019-30738892,
  author  = {McQuade, A. and Blurton-Jones, M.},
  title   = {{Microglia in Alzheimer's Disease: Exploring How Genetics and Phenotype Influence Risk}},
  journal = {Journal of molecular biology},
  year    = {2019},
  doi     = {10.1016/j.jmb.2019.01.045},
  pmid    = {30738892},
  url     = {https://doi.org/10.1016/j.jmb.2019.01.045}
}

@article{hillerstrom2024-38480678,
  author  = {Hillerstrom, Hampus and Fisher, Richard Alan and Janicki, Matthew P. and Chicoine, Brian Allen and Christian, Bradley T. and Esbensen, Anna J. and Esralew, Lucille and Fortea, Juan and others},
  title   = {{Adapting prescribing criteria for amyloid‐targeted antibodies for adults with Down syndrome}},
  journal = {Alzheimer s \& Dementia},
  year    = {2024},
  doi     = {10.1002/alz.13778},
  pmid    = {38480678},
  url     = {https://doi.org/10.1002/alz.13778}
}

@article{ports2025-40034839,
  author  = {Ports, Kayleen Deanna and Dai, Jiahui and Conniff, Kyle R and Corrada, María M. and Manson, Spero M. and O’Connell, Joan M. and Jiang, Luohua},
  title   = {{Machine learning to predict dementia for American Indian and Alaska native peoples: a retrospective cohort study}},
  journal = {The Lancet Regional Health - Americas},
  year    = {2025},
  doi     = {10.1016/j.lana.2025.101013},
  pmid    = {40034839},
  url     = {https://doi.org/10.1016/j.lana.2025.101013}
}

@article{mungas2025-40747592,
  author  = {Mungas, Dan and Gavett, Brandon E. and Rojas‐Saunero, Liliana Paloma and Zhou, Yixuan and Hayes‐Larson, Eleanor and Shaw, Crystal L. and Farias, Sarah Tomaszewski and Widaman, Keith F. and others},
  title   = {{Machine learning diagnosis of cognitive impairment and dementia in harmonized older adult cohorts}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70508},
  pmid    = {40747592},
  url     = {https://doi.org/10.1002/alz.70508}
}

@article{chien2013-ac703d18,
  author  = {Chien, David T. and Szardenings, Anna Katrin and Bahri, Shadfar and Walsh, Joseph C. and Mu, Fanrong and Xia, Chunfang A. and Shankle, William Rodman and Lerner, Alan Jay and Su, Min‐Ying and Elizarov, Arkadij M. and Kolb, Hartmuth Christian},
  title   = {{Early Clinical PET Imaging Results with the Novel PHF-Tau Radioligand [F18]-T808}},
  journal = {Journal of Alzheimer s Disease},
  year    = {2013},
  doi     = {10.3233/jad-130098},
  url     = {https://doi.org/10.3233/jad-130098}
}

@article{chien2013-23234879,
  author  = {Chien, David T. and Bahri, Shadfar and Szardenings, Anna Katrin and Walsh, Joseph C. and Mu, Fanrong and Su, Min‐Ying and Shankle, William Rodman and Elizarov, Arkadij M. and Kolb, Hartmuth Christian},
  title   = {{Early Clinical PET Imaging Results with the Novel PHF-Tau Radioligand [F-18]-T807}},
  journal = {Journal of Alzheimer s Disease},
  year    = {2013},
  doi     = {10.3233/jad-122059},
  pmid    = {23234879},
  url     = {https://doi.org/10.3233/jad-122059}
}

@article{shcherbinin2016-27151986,
  author  = {Shcherbinin, S. and Schwarz, A. J. and Joshi, A. and Navitsky, M. and Flitter, M. and Shankle, W. R. and Devous, M. D. and Mintun, M. A.},
  title   = {{Kinetics of the Tau PET Tracer 18F-AV-1451 (T807) in Subjects with Normal Cognitive Function, Mild Cognitive Impairment, and Alzheimer Disease}},
  journal = {Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year    = {2016},
  doi     = {10.2967/jnumed.115.170027},
  pmid    = {27151986},
  url     = {https://doi.org/10.2967/jnumed.115.170027}
}

@article{chow2015-25614473,
  author  = {Chow, N. and Hwang, K. S. and Hurtz, S. and Green, A. E. and Somme, J. H. and Thompson, P. M. and Elashoff, D. A. and Jack, C. R. and others},
  title   = {{Comparing 3T and 1.5T MRI for mapping hippocampal atrophy in the Alzheimer's Disease Neuroimaging Initiative}},
  journal = {AJNR. American journal of neuroradiology},
  year    = {2015},
  doi     = {10.3174/ajnr.a4228},
  pmid    = {25614473},
  url     = {https://doi.org/10.3174/ajnr.a4228}
}

@article{bruckner2011-21379414,
  author  = {Bruckner, T. A. and Scheffler, R. M. and Shen, G. and Yoon, J. and Chisholm, D. and Morris, J. and Fulton, B. D. and Dal Poz, M. R. and others},
  title   = {{The mental health workforce gap in low- and middle-income countries: a needs-based approach}},
  journal = {Bulletin of the World Health Organization},
  year    = {2011},
  doi     = {10.2471/blt.10.082784},
  pmid    = {21379414},
  url     = {https://doi.org/10.2471/blt.10.082784}
}

@article{coskun2012-21871538,
  author  = {Coskun, P. and Wyrembak, J. and Schriner, S. E. and Chen, H. W. and Marciniack, C. and Laferla, F. and Wallace, D. C.},
  title   = {{A mitochondrial etiology of Alzheimer and Parkinson disease}},
  journal = {Biochimica et biophysica acta},
  year    = {2012},
  doi     = {10.1016/j.bbagen.2011.08.008},
  pmid    = {21871538},
  url     = {https://doi.org/10.1016/j.bbagen.2011.08.008}
}

@article{frost2013-23747948,
  author  = {Frost, J. L. and Le, K. X. and Cynis, H. and Ekpo, E. and Kleinschmidt, M. and Palmour, R. M. and Ervin, F. R. and Snigdha, S. and others},
  title   = {{Pyroglutamate-3 amyloid-β deposition in the brains of humans, non-human primates, canines, and Alzheimer disease-like transgenic mouse models}},
  journal = {The American journal of pathology},
  year    = {2013},
  doi     = {10.1016/j.ajpath.2013.05.005},
  pmid    = {23747948},
  url     = {https://doi.org/10.1016/j.ajpath.2013.05.005}
}

@article{cenini2012-22009041,
  author  = {Cenini, G. and Dowling, A. L. and Beckett, T. L. and Barone, E. and Mancuso, C. and Murphy, M. P. and Levine, H. and Lott, I. T. and others},
  title   = {{Association between frontal cortex oxidative damage and beta-amyloid as a function of age in Down syndrome}},
  journal = {Biochimica et biophysica acta},
  year    = {2012},
  doi     = {10.1016/j.bbadis.2011.10.001},
  pmid    = {22009041},
  url     = {https://doi.org/10.1016/j.bbadis.2011.10.001}
}

@article{dass2025-41104603,
  author  = {Dass, D. and Dang, L. T. and Xicota, L. and Krinsky-McHale, S. and Kannappan, B. and Brickman, A. M. and Christian, B. T. and Head, E. and others},
  title   = {{Examination of metabolic syndrome in Down syndrome and association with dementia}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2025},
  doi     = {10.1002/alz.70799},
  pmid    = {41104603},
  url     = {https://doi.org/10.1002/alz.70799}
}

@article{yoon2025-40917568,
  author  = {Yoon, D. M. and Plante, D. T. and Fleming, V. and Handen, B. and Lao, P. and Peven, J. and Christian, B. and Okonkwo, O. and others},
  title   = {{Preliminary investigation of obstructive sleep apnea and Alzheimer's disease in down syndrome}},
  journal = {Sleep advances : a journal of the Sleep Research Society},
  year    = {2025},
  doi     = {10.1093/sleepadvances/zpaf044},
  pmid    = {40917568},
  url     = {https://doi.org/10.1093/sleepadvances/zpaf044}
}

@article{schworer2025-40254895,
  author  = {Schworer, E. K. and Handen, B. L. and Krinsky-McHale, S. and Hom, C. L. and Clare, I. C. H. and Harp, J. P. and Pulsifer, M. B. and Mapstone, M. and others},
  title   = {{Modified Cued Recall Test: Longitudinal Analysis of Test Versions and Item Recall in Adults With Down Syndrome}},
  journal = {Journal of intellectual disability research : JIDR},
  year    = {2025},
  doi     = {10.1111/jir.13237},
  pmid    = {40254895},
  url     = {https://doi.org/10.1111/jir.13237}
}

@article{green2007-17442823,
  author  = {Green, K. N. and Martinez-Coria, H. and Khashwji, H. and Hall, E. B. and Yurko-Mauro, K. A. and Ellis, L. and LaFerla, F. M.},
  title   = {{Dietary docosahexaenoic acid and docosapentaenoic acid ameliorate amyloid-beta and tau pathology via a mechanism involving presenilin 1 levels}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2007},
  doi     = {10.1523/jneurosci.0055-07.2007},
  pmid    = {17442823},
  url     = {https://doi.org/10.1523/jneurosci.0055-07.2007}
}

@article{fonseca2009-19561098,
  author  = {Fonseca, M. I. and Ager, R. R. and Chu, S. H. and Yazan, O. and Sanderson, S. D. and LaFerla, F. M. and Taylor, S. M. and Woodruff, T. M. and others},
  title   = {{Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease}},
  journal = {Journal of immunology (Baltimore, Md. : 1950)},
  year    = {2009},
  doi     = {10.4049/jimmunol.0901005},
  pmid    = {19561098},
  url     = {https://doi.org/10.4049/jimmunol.0901005}
}

@article{nichol2008-18400101,
  author  = {Nichol, K. E. and Poon, W. W. and Parachikova, A. I. and Cribbs, D. H. and Glabe, C. G. and Cotman, C. W.},
  title   = {{Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid}},
  journal = {Journal of neuroinflammation},
  year    = {2008},
  doi     = {10.1186/1742-2094-5-13},
  pmid    = {18400101},
  url     = {https://doi.org/10.1186/1742-2094-5-13}
}

@article{dai2025-40833693,
  author  = {Dai, Jiahui and Chau, T T and Corrada, María M. and Manson, Spero M. and O’Connell, Joan M. and Jiang, Luohua},
  title   = {{Race and Ethnicity and Comorbidities Among Medicare Beneficiaries With Young-Onset Dementia}},
  journal = {JAMA Network Open},
  year    = {2025},
  doi     = {10.1001/jamanetworkopen.2025.28001},
  pmid    = {40833693},
  url     = {https://doi.org/10.1001/jamanetworkopen.2025.28001}
}

@article{head2026-41505228,
  author  = {Head, Elizabeth and Cohen, Ann D. and Fortea, Juan and McGlinchey, Eimear},
  title   = {{Novel insights into Alzheimer's disease through the study of individuals with Down syndrome}},
  journal = {Alzheimer s \& Dementia},
  year    = {2026},
  doi     = {10.1002/alz.71074},
  pmid    = {41505228},
  url     = {https://doi.org/10.1002/alz.71074}
}

@article{blurtonjones2014-25022790,
  author  = {Blurton-Jones, M. and Spencer, B. and Michael, S. and Castello, N. A. and Agazaryan, A. A. and Davis, J. L. and Müller, F. J. and Loring, J. F. and others},
  title   = {{Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models}},
  journal = {Stem cell research \& therapy},
  year    = {2014},
  doi     = {10.1186/scrt440},
  pmid    = {25022790},
  url     = {https://doi.org/10.1186/scrt440}
}

@article{fichou2015-25918405,
  author  = {Fichou, Y. and Schirò, G. and Gallat, F. X. and Laguri, C. and Moulin, M. and Combet, J. and Zamponi, M. and Härtlein, M. and others},
  title   = {{Hydration water mobility is enhanced around tau amyloid fibers}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2015},
  doi     = {10.1073/pnas.1422824112},
  pmid    = {25918405},
  url     = {https://doi.org/10.1073/pnas.1422824112}
}

@article{abdelmoity2025-40977577,
  author  = {Abdelmoity, O. and Wisch, J. K. and Kennedy, J. T. and Goyal, M. and Vlassenko, A. and Flores, S. and Handen, B. L. and Head, E. and others},
  title   = {{Cross-Sectional FDG in Down Syndrome and Autosomal Dominant Alzheimer's Disease}},
  journal = {Annals of neurology},
  year    = {2025},
  doi     = {10.1002/ana.78002},
  pmid    = {40977577},
  url     = {https://doi.org/10.1002/ana.78002}
}

@article{gandy2010-20641005,
  author  = {Gandy, S. and Simon, A. J. and Steele, J. W. and Lublin, A. L. and Lah, J. J. and Walker, L. C. and Levey, A. I. and Krafft, G. A. and others},
  title   = {{Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomers}},
  journal = {Annals of neurology},
  year    = {2010},
  doi     = {10.1002/ana.22052},
  pmid    = {20641005},
  url     = {https://doi.org/10.1002/ana.22052}
}

@article{vanderlip2025-40577676,
  author  = {Vanderlip, Casey R. and Stark, Craig E.L.},
  title   = {{Time Course and Severity of Cognitive Changes as a Function of Aβ Positivity and APOE Genotype in Alzheimer Disease}},
  journal = {Neurology},
  year    = {2025},
  doi     = {10.1212/wnl.0000000000213853},
  pmid    = {40577676},
  url     = {https://doi.org/10.1212/wnl.0000000000213853}
}

@article{vanderlip2026-42741980,
  author  = {Vanderlip, Casey R. and Stark, Craig E.L.},
  title   = {{Digital cognitive phenotyping enhances risk stratification in preclinical Alzheimer's disease}},
  journal = {Alzheimer s \& Dementia},
  year    = {2026},
  doi     = {10.1002/alz.71834},
  pmid    = {42741980},
  url     = {https://doi.org/10.1002/alz.71834}
}

@article{brandao2025-39813317,
  author  = {Brandão, Wesley Nogueira and Jain, Nimansha and Yin, Zhuoran and Kleemann, Kilian L. and Carpenter, Madison and Bao, Xin and Serrano, Javier Remolina and Tycksen, Eric and others},
  title   = {{Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy}},
  journal = {Science Translational Medicine},
  year    = {2025},
  doi     = {10.1126/scitranslmed.adk3690},
  pmid    = {39813317},
  url     = {https://doi.org/10.1126/scitranslmed.adk3690}
}

@article{short2019-31530940,
  author  = {Short, A. K. and Baram, T. Z.},
  title   = {{Early-life adversity and neurological disease: age-old questions and novel answers}},
  journal = {Nature reviews. Neurology},
  year    = {2019},
  doi     = {10.1038/s41582-019-0246-5},
  pmid    = {31530940},
  url     = {https://doi.org/10.1038/s41582-019-0246-5}
}

@article{tramutola2020-31987911,
  author  = {Tramutola, A. and Lanzillotta, C. and Di Domenico, F. and Head, E. and Butterfield, D. A. and Perluigi, M. and Barone, E.},
  title   = {{Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome}},
  journal = {Neurobiology of disease},
  year    = {2020},
  doi     = {10.1016/j.nbd.2020.104772},
  pmid    = {31987911},
  url     = {https://doi.org/10.1016/j.nbd.2020.104772}
}

@article{nelson2005-15795053,
  author  = {Nelson, L. and Johnson, J. K. and Freedman, M. and Lott, I. and Groot, J. and Chang, M. and Milgram, N. W. and Head, E.},
  title   = {{Learning and memory as a function of age in Down syndrome: a study using animal-based tasks}},
  journal = {Progress in neuro-psychopharmacology \& biological psychiatry},
  year    = {2005},
  doi     = {10.1016/j.pnpbp.2004.12.009},
  pmid    = {15795053},
  url     = {https://doi.org/10.1016/j.pnpbp.2004.12.009}
}

@article{tomic2009-19523517,
  author  = {Tomic, J. L. and Pensalfini, A. and Head, E. and Glabe, C. G.},
  title   = {{Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction}},
  journal = {Neurobiology of disease},
  year    = {2009},
  doi     = {10.1016/j.nbd.2009.05.024},
  pmid    = {19523517},
  url     = {https://doi.org/10.1016/j.nbd.2009.05.024}
}

@article{parachikova2007-17052803,
  author  = {Parachikova, A. and Agadjanyan, M. G. and Cribbs, D. H. and Blurton-Jones, M. and Perreau, V. and Rogers, J. and Beach, T. G. and Cotman, C. W.},
  title   = {{Inflammatory changes parallel the early stages of Alzheimer disease}},
  journal = {Neurobiology of aging},
  year    = {2007},
  doi     = {10.1016/j.neurobiolaging.2006.08.014},
  pmid    = {17052803},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2006.08.014}
}

@article{medeiros2013-23063604,
  author  = {Medeiros, R. and LaFerla, F. M.},
  title   = {{Astrocytes: conductors of the Alzheimer disease neuroinflammatory symphony}},
  journal = {Experimental neurology},
  year    = {2013},
  doi     = {10.1016/j.expneurol.2012.10.007},
  pmid    = {23063604},
  url     = {https://doi.org/10.1016/j.expneurol.2012.10.007}
}

@article{vehmas2003-12498966,
  author  = {Vehmas, A. K. and Kawas, C. H. and Stewart, W. F. and Troncoso, J. C.},
  title   = {{Immune reactive cells in senile plaques and cognitive decline in Alzheimer's disease}},
  journal = {Neurobiology of aging},
  year    = {2003},
  doi     = {10.1016/s0197-4580(02)00090-8},
  pmid    = {12498966},
  url     = {https://doi.org/10.1016/s0197-4580(02)00090-8}
}

@article{thorwald2025-41444200,
  author  = {Thorwald, Max Andrew and Godoy-Lugo, José Arquimides and Vermulst, Marc and Forman, Henry Jay and Head, Elizabeth and Finch, Caleb E.},
  title   = {{Down syndrome with Alzheimer's disease brains have increased iron and associated lipid peroxidation consistent with ferroptosis}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70855_105930},
  pmid    = {41444200},
  url     = {https://doi.org/10.1002/alz70855_105930}
}

@article{valencia2025-41449092,
  author  = {Valencia, Diana K. and Silverman, Wayne P. and Hartley, Sigan L. and Zaman, Shahid H. and Brickman, Adam and Lai, Florence Y. and Mapstone, Mark E. and Krinsky‐McHale, Sharon J. and others},
  title   = {{Factors Associated with Atypical Cognitive Trajectories in Older Adults with Down Syndrome}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70857_105703},
  pmid    = {41449092},
  url     = {https://doi.org/10.1002/alz70857_105703}
}

@article{day2000-10961029,
  author  = {Day, K. and Carreon, D. and Stump, C.},
  title   = {{The therapeutic design of environments for people with dementia: a review of the empirical research}},
  journal = {The Gerontologist},
  year    = {2000},
  doi     = {10.1093/geront/40.4.397},
  pmid    = {10961029},
  url     = {https://doi.org/10.1093/geront/40.4.397}
}

@article{anderson2000-10924764,
  author  = {Anderson, A. J. and Stoltzner, S. and Lai, F. and Su, J. and Nixon, R. A.},
  title   = {{Morphological and biochemical assessment of DNA damage and apoptosis in Down syndrome and Alzheimer disease, and effect of postmortem tissue archival on TUNEL}},
  journal = {Neurobiology of aging},
  year    = {2000},
  doi     = {10.1016/s0197-4580(00)00126-3},
  pmid    = {10924764},
  url     = {https://doi.org/10.1016/s0197-4580(00)00126-3}
}

@article{lanzillotta2021-32795489,
  author  = {Lanzillotta, C. and Zuliani, I. and Tramutola, A. and Barone, E. and Blarzino, C. and Folgiero, V. and Caforio, M. and Valentini, D. and others},
  title   = {{Chronic PERK induction promotes Alzheimer-like neuropathology in Down syndrome: Insights for therapeutic intervention}},
  journal = {Progress in neurobiology},
  year    = {2021},
  doi     = {10.1016/j.pneurobio.2020.101892},
  pmid    = {32795489},
  url     = {https://doi.org/10.1016/j.pneurobio.2020.101892}
}

@article{mangale2020-32449994,
  author  = {Mangale, V. and Syage, A. R. and Ekiz, H. A. and Skinner, D. D. and Cheng, Y. and Stone, C. L. and Brown, R. M. and O'Connell, R. M. and others},
  title   = {{Microglia influence host defense, disease, and repair following murine coronavirus infection of the central nervous system}},
  journal = {Glia},
  year    = {2020},
  doi     = {10.1002/glia.23844},
  pmid    = {32449994},
  url     = {https://doi.org/10.1002/glia.23844}
}

@article{tran2023-36803190,
  author  = {Tran, K. M. and Kawauchi, S. and Kramár, E. A. and Rezaie, N. and Liang, H. Y. and Sakr, J. S. and Gomez-Arboledas, A. and Arreola, M. A. and others},
  title   = {{A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques}},
  journal = {Molecular neurodegeneration},
  year    = {2023},
  doi     = {10.1186/s13024-023-00598-4},
  pmid    = {36803190},
  url     = {https://doi.org/10.1186/s13024-023-00598-4}
}

@article{brothers2025-41444861,
  author  = {Brothers, Courtney E and Wisch, Julie K. and Handen, Benjamin L. and Lao, Patrick J. and Ances, Beau M. and Kennedy, James Tyler and Zammit, Matthew D. and Christian, Bradley T. and others},
  title   = {{Cardiovascular Risk Composite and Time of Amyloid Accumulation and Cognitive Decline in Down Syndrome Alzheimer's Disease}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70857_099395},
  pmid    = {41444861},
  url     = {https://doi.org/10.1002/alz70857_099395}
}

@article{chung2026-02ad0ff8,
  author  = {Chung, Paul A. and Fleming, Victoria and Reid, K and Plante, D and Hom, Christy L. and Ances, Beau M. and Handen, B and Christian, Bradley T. and others},
  title   = {{B31-13 Circadian Rest-Activity Rhythm and Alzheimer’s Disease Biomarkers in Adults With Down Syndrome}},
  journal = {American Journal of Respiratory and Critical Care Medicine},
  year    = {2026},
  doi     = {10.1093/ajrccm/aamag162.6475},
  url     = {https://doi.org/10.1093/ajrccm/aamag162.6475}
}

@article{cacerespalomo2025-41388301,
  author  = {Cáceres-Palomo, Laura and Sánchez‐Mejías, Elisabeth and Trujillo‐Estrada, Laura and Pérez-Moreno, Juan José and Lopez-Oliva, Elba and Lim, Tau En and DeFlitch, Leah and Chang, Serena H. and others},
  title   = {{Human iPSC-derived APOE4/4 Alzheimer´s disease astrocytes exhibit a senescent and pro-inflammatory state that compromises neuronal support}},
  journal = {Journal of Neuroinflammation},
  year    = {2025},
  doi     = {10.1186/s12974-025-03607-z},
  pmid    = {41388301},
  url     = {https://doi.org/10.1186/s12974-025-03607-z}
}

@article{parankusham2026-7da4a6e3,
  author  = {Parankusham, H. and Vanderlip, C. and Birkenbihl, C. and Krishna, E. and Ugboaja, C. and Budson, A. and Frank, B.},
  title   = {{A Two-Stage Plasma Biomarker Algorithm Reduces Amyloid PET Use and the p-Tau217 Gray Zone}},
  journal = {Annals of clinical and translational neurology},
  year    = {2026},
  doi     = {10.64898/2026.02.03.26345302},
  url     = {https://doi.org/10.64898/2026.02.03.26345302}
}

@article{lott2005-15639317,
  author  = {Lott, I. T. and Head, E.},
  title   = {{Alzheimer disease and Down syndrome: factors in pathogenesis}},
  journal = {Neurobiology of aging},
  year    = {2005},
  doi     = {10.1016/j.neurobiolaging.2004.08.005},
  pmid    = {15639317},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2004.08.005}
}

@article{head2003-14533781,
  author  = {Head, E. and Lott, I. T. and Hof, P. R. and Bouras, C. and Su, J. H. and Kim, R. and Haier, R. and Cotman, C. W.},
  title   = {{Parallel compensatory and pathological events associated with tau pathology in middle aged individuals with Down syndrome}},
  journal = {Journal of neuropathology and experimental neurology},
  year    = {2003},
  doi     = {10.1093/jnen/62.9.917},
  pmid    = {14533781},
  url     = {https://doi.org/10.1093/jnen/62.9.917}
}

@article{levine2017-28385551,
  author  = {LeVine, H. and Spielmann, H. P. and Matveev, S. and Cauvi, F. M. and Murphy, M. P. and Beckett, T. L. and McCarty, K. and Lott, I. T. and others},
  title   = {{Down syndrome: age-dependence of PiB binding in postmortem frontal cortex across the lifespan}},
  journal = {Neurobiology of aging},
  year    = {2017},
  doi     = {10.1016/j.neurobiolaging.2017.03.005},
  pmid    = {28385551},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2017.03.005}
}

@article{didomenico2025-41269384,
  author  = {Di Domenico, F. and Greco, V. and Tramutola, A. and Rataj-Baniowska, M. and Barone, E. and Lanzillotta, C. and Pieroni, L. and Butterfield, D. A. and others},
  title   = {{Proteome Signature of Alzheimer-Like Phenotypes in Frontal Cortices From Young and Old Individuals With Down Syndrome}},
  journal = {Molecular neurobiology},
  year    = {2025},
  doi     = {10.1007/s12035-025-05432-0},
  pmid    = {41269384},
  url     = {https://doi.org/10.1007/s12035-025-05432-0}
}

@article{mastroeni2017-27793643,
  author  = {Mastroeni, D. and Khdour, O. M. and Delvaux, E. and Nolz, J. and Olsen, G. and Berchtold, N. and Cotman, C. and Hecht, S. M. and others},
  title   = {{Nuclear but not mitochondrial-encoded oxidative phosphorylation genes are altered in aging, mild cognitive impairment, and Alzheimer's disease}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2017},
  doi     = {10.1016/j.jalz.2016.09.003},
  pmid    = {27793643},
  url     = {https://doi.org/10.1016/j.jalz.2016.09.003}
}

@article{pensalfini2014-25092575,
  author  = {Pensalfini, A. and Albay, R. and Rasool, S. and Wu, J. W. and Hatami, A. and Arai, H. and Margol, L. and Milton, S. and others},
  title   = {{Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques}},
  journal = {Neurobiology of disease},
  year    = {2014},
  doi     = {10.1016/j.nbd.2014.07.011},
  pmid    = {25092575},
  url     = {https://doi.org/10.1016/j.nbd.2014.07.011}
}

@article{kimonis2008-18845250,
  author  = {Kimonis, V. E. and Fulchiero, E. and Vesa, J. and Watts, G.},
  title   = {{VCP disease associated with myopathy, Paget disease of bone and frontotemporal dementia: review of a unique disorder}},
  journal = {Biochimica et biophysica acta},
  year    = {2008},
  doi     = {10.1016/j.bbadis.2008.09.003},
  pmid    = {18845250},
  url     = {https://doi.org/10.1016/j.bbadis.2008.09.003}
}

@article{afagh1996-8593893,
  author  = {Afagh, A. and Cummings, B. J. and Cribbs, D. H. and Cotman, C. W. and Tenner, A. J.},
  title   = {{Localization and cell association of C1q in Alzheimer's disease brain}},
  journal = {Experimental neurology},
  year    = {1996},
  doi     = {10.1006/exnr.1996.0043},
  pmid    = {8593893},
  url     = {https://doi.org/10.1006/exnr.1996.0043}
}

@article{parachikova2008-18258444,
  author  = {Parachikova, A. and Nichol, K. E. and Cotman, C. W.},
  title   = {{Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition}},
  journal = {Neurobiology of disease},
  year    = {2008},
  doi     = {10.1016/j.nbd.2007.12.008},
  pmid    = {18258444},
  url     = {https://doi.org/10.1016/j.nbd.2007.12.008}
}

@article{meeker2023-b608ec21,
  author  = {Meeker, Karin L. and Ances, Beau M. and Petersen, Melissa E. and Barber, Robert C. and Yaffe, Kristine S. and Zhou, Zhengyang and Llibre‐Guerra, Jorge J. and Zhang, Fan and others},
  title   = {{Effects of structural and social determinants of health and comorbidities on ethno‐racial differences in ATN plasma biomarkers of Alzheimer’s disease: A HABS‐HD study}},
  journal = {Alzheimer s \& Dementia},
  year    = {2023},
  doi     = {10.1002/alz.078605},
  url     = {https://doi.org/10.1002/alz.078605}
}

@article{sarsoza2009-19360426,
  author  = {Sarsoza, F. and Saing, T. and Kayed, R. and Dahlin, R. and Dick, M. and Broadwater-Hollifield, C. and Mobley, S. and Lott, I. and others},
  title   = {{A fibril-specific, conformation-dependent antibody recognizes a subset of Abeta plaques in Alzheimer disease, Down syndrome and Tg2576 transgenic mouse brain}},
  journal = {Acta neuropathologica},
  year    = {2009},
  doi     = {10.1007/s00401-009-0530-3},
  pmid    = {19360426},
  url     = {https://doi.org/10.1007/s00401-009-0530-3}
}

@article{dohl2025-40042516,
  author  = {Dohl, J. and Treadwell, Z. and Norris, C. and Head, E.},
  title   = {{Calcineurin inhibition may prevent Alzheimer disease in people with Down syndrome}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2025},
  doi     = {10.1002/alz.70034},
  pmid    = {40042516},
  url     = {https://doi.org/10.1002/alz.70034}
}

@article{knauer1992-1502155,
  author  = {Knauer, M. F. and Soreghan, B. and Burdick, D. and Kosmoski, J. and Glabe, C. G.},
  title   = {{Intracellular accumulation and resistance to degradation of the Alzheimer amyloid A4/beta protein}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {1992},
  doi     = {10.1073/pnas.89.16.7437},
  pmid    = {1502155},
  url     = {https://doi.org/10.1073/pnas.89.16.7437}
}

@article{kammesheidt1992-1438289,
  author  = {Kammesheidt, A. and Boyce, F. M. and Spanoyannis, A. F. and Cummings, B. J. and Ortegón, M. and Cotman, C. and Vaught, J. L. and Neve, R. L.},
  title   = {{Deposition of beta/A4 immunoreactivity and neuronal pathology in transgenic mice expressing the carboxyl-terminal fragment of the Alzheimer amyloid precursor in the brain}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {1992},
  doi     = {10.1073/pnas.89.22.10857},
  pmid    = {1438289},
  url     = {https://doi.org/10.1073/pnas.89.22.10857}
}

@article{temkingreener2005-16365610,
  author  = {Temkin‐Greener, Helena and Bajorska, Alina and Mukamel, Dana B.},
  title   = {{Disenrollment From an Acute/Long-Term Managed Care Program (PACE)}},
  journal = {Medical Care},
  year    = {2005},
  doi     = {10.1097/01.mlr.0000188920.19129.89},
  pmid    = {16365610},
  url     = {https://doi.org/10.1097/01.mlr.0000188920.19129.89}
}

@article{saeed2025-40034508,
  author  = {Saeed, Anum and Chang, Yue-Fang and Swanson, Justin and Vu, Michael and Mapstone, Mark E. and Villemagne, Victor L. and Snitz, Beth Ellen and Royse, Sarah K. and others},
  title   = {{Association of mid-life cardiovascular risk with biomarkers of Alzheimer's disease, neurodegeneration, and white matter hyperintensities: Heart SCORE brain study}},
  journal = {Journal of Alzheimer s Disease Reports},
  year    = {2025},
  doi     = {10.1177/25424823241299297},
  pmid    = {40034508},
  url     = {https://doi.org/10.1177/25424823241299297}
}

@article{cassano2012-22035587,
  author  = {Cassano, T. and Serviddio, G. and Gaetani, S. and Romano, A. and Dipasquale, P. and Cianci, S. and Bellanti, F. and Laconca, L. and others},
  title   = {{Glutamatergic alterations and mitochondrial impairment in a murine model of Alzheimer disease}},
  journal = {Neurobiology of aging},
  year    = {2012},
  doi     = {10.1016/j.neurobiolaging.2011.09.021},
  pmid    = {22035587},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2011.09.021}
}

@article{head2007-17361036,
  author  = {Head, E. and Lott, I. T. and Patterson, D. and Doran, E. and Haier, R. J.},
  title   = {{Possible compensatory events in adult Down syndrome brain prior to the development of Alzheimer disease neuropathology: targets for nonpharmacological intervention}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2007},
  doi     = {10.3233/jad-2007-11110},
  pmid    = {17361036},
  url     = {https://doi.org/10.3233/jad-2007-11110}
}

@article{martin2014-24927707,
  author  = {Martin, S. B. and Dowling, A. L. and Lianekhammy, J. and Lott, I. T. and Doran, E. and Murphy, M. P. and Beckett, T. L. and Schmitt, F. A. and others},
  title   = {{Synaptophysin and synaptojanin-1 in Down syndrome are differentially affected by Alzheimer's disease}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2014},
  doi     = {10.3233/jad-140795},
  pmid    = {24927707},
  url     = {https://doi.org/10.3233/jad-140795}
}

@article{helman2019-30452414,
  author  = {Helman, A. M. and Siever, M. and McCarty, K. L. and Lott, I. T. and Doran, E. and Abner, E. L. and Schmitt, F. A. and Head, E.},
  title   = {{Microbleeds and Cerebral Amyloid Angiopathy in the Brains of People with Down Syndrome with Alzheimer's Disease}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2019},
  doi     = {10.3233/jad-180589},
  pmid    = {30452414},
  url     = {https://doi.org/10.3233/jad-180589}
}

@article{rosas2020-33204811,
  author  = {Rosas, H. D. and Hsu, E. and Mercaldo, N. D. and Lai, F. and Pulsifer, M. and Keator, D. and Brickman, A. M. and Price, J. and others},
  title   = {{Alzheimer-related altered white matter microstructural integrity in Down syndrome: A model for sporadic AD?}},
  journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)},
  year    = {2020},
  doi     = {10.1002/dad2.12040},
  pmid    = {33204811},
  url     = {https://doi.org/10.1002/dad2.12040}
}

@article{lott2022-36419175,
  author  = {Lott, I. T. and Kirby, K. A. and Doran, E. and Grill, J. D.},
  title   = {{Research attitudes in families of individuals with Down syndrome: importance for clinical trials}},
  journal = {Alzheimer's research \& therapy},
  year    = {2022},
  doi     = {10.1186/s13195-022-01120-6},
  pmid    = {36419175},
  url     = {https://doi.org/10.1186/s13195-022-01120-6}
}

@article{armstrong2025-40636063,
  author  = {Armstrong, Melissa J. and Grill, Joshua D. and Tropea, Thomas Francis},
  title   = {{It is time to share Alzheimer biomarker results in dementia with Lewy bodies}},
  journal = {Alzheimer s \& Dementia Diagnosis Assessment \& Disease Monitoring},
  year    = {2025},
  doi     = {10.1002/dad2.70144},
  pmid    = {40636063},
  url     = {https://doi.org/10.1002/dad2.70144}
}

@article{martini2022-35472307,
  author  = {Martini, A. C. and Gross, T. J. and Head, E. and Mapstone, M.},
  title   = {{Beyond amyloid: Immune, cerebrovascular, and metabolic contributions to Alzheimer disease in people with Down syndrome}},
  journal = {Neuron},
  year    = {2022},
  doi     = {10.1016/j.neuron.2022.04.001},
  pmid    = {35472307},
  url     = {https://doi.org/10.1016/j.neuron.2022.04.001}
}

@article{clina2025-41100837,
  author  = {Clina, J. G. and Helsel, B. C. and Hartley, S. L. and Fleming-Batayneh, V. L. and Handen, B. and Christian, B. and Head, E. and Mapstone, M. and others},
  title   = {{The joint association of obesity and physical activity on cognitive function in Down syndrome}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2025},
  doi     = {10.1177/13872877251386474},
  pmid    = {41100837},
  url     = {https://doi.org/10.1177/13872877251386474}
}

@article{oh2025-41356564,
  author  = {Oh, Kyeung Mi and Hong, Sung-Soo and Beran, Krista and Song, Yeonsu and Lee, Jung‐Ah},
  title   = {{Digital Health Literacy and Self-Efficacy in Using Digital Health Resources Among Caregivers of Individuals with Alzheimer’s Disease and Related Dementias}},
  journal = {Sage Open Aging},
  year    = {2025},
  doi     = {10.1177/30495334251398089},
  pmid    = {41356564},
  url     = {https://doi.org/10.1177/30495334251398089}
}

@article{anderson2025-40425038,
  author  = {Anderson, Elizabeth and Goins, R. Turner and Abdulsalam, Ruqoyat and Jiang, Luohua and O’Connell, Joan M.},
  title   = {{End-of Life Care Disparities Experienced by American Indian and Alaska Natives Peoples: An Analysis of Data from the 2019 Medicare Master Beneficiary Summary File}},
  journal = {Journal of Palliative Medicine},
  year    = {2025},
  doi     = {10.1089/jpm.2024.0481},
  pmid    = {40425038},
  url     = {https://doi.org/10.1089/jpm.2024.0481}
}

@article{lott2006-17168651,
  author  = {Lott, I. T. and Head, E. and Doran, E. and Busciglio, J.},
  title   = {{Beta-amyloid, oxidative stress and down syndrome}},
  journal = {Current Alzheimer research},
  year    = {2006},
  doi     = {10.2174/156720506779025305},
  pmid    = {17168651},
  url     = {https://doi.org/10.2174/156720506779025305}
}

@article{lott2012-22206998,
  author  = {Lott, I. T.},
  title   = {{Antioxidants in Down syndrome}},
  journal = {Biochimica et biophysica acta},
  year    = {2012},
  doi     = {10.1016/j.bbadis.2011.12.010},
  pmid    = {22206998},
  url     = {https://doi.org/10.1016/j.bbadis.2011.12.010}
}

@article{vannostrand1991-1946448,
  author  = {Van Nostrand, W. E. and Farrow, J. S. and Wagner, S. L. and Bhasin, R. and Goldgaber, D. and Cotman, C. W. and Cunningham, D. D.},
  title   = {{The predominant form of the amyloid beta-protein precursor in human brain is protease nexin 2}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {1991},
  doi     = {10.1073/pnas.88.22.10302},
  pmid    = {1946448},
  url     = {https://doi.org/10.1073/pnas.88.22.10302}
}

@article{davtyan2019-31847886,
  author  = {Davtyan, H. and Hovakimyan, A. and Kiani Shabestari, S. and Antonyan, T. and Coburn, M. A. and Zagorski, K. and Chailyan, G. and Petrushina, I. and others},
  title   = {{Testing a MultiTEP-based combination vaccine to reduce Aβ and tau pathology in Tau22/5xFAD bigenic mice}},
  journal = {Alzheimer's research \& therapy},
  year    = {2019},
  doi     = {10.1186/s13195-019-0556-2},
  pmid    = {31847886},
  url     = {https://doi.org/10.1186/s13195-019-0556-2}
}

@article{ching2025-41452246,
  author  = {Ching, Annie and Wong, Anson and Nam, Bora and Tzuang, Marian and Nguyen, Linda and Yum, Seoyeon and Deng, Jessie and Huang, Daren and others},
  title   = {{Asian Americans \& Racism: Individual and Structural Experiences (ARISE) Pilot Study: Cultural and Linguistic Considerations in Studying Chinese, Vietnamese, and Korean American Older Adults}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70857_107405},
  pmid    = {41452246},
  url     = {https://doi.org/10.1002/alz70857_107405}
}

@article{george2025-41230793,
  author  = {George, Grace C. and Keller, Sarah A. and Abner, Erin L. and Adar, Sara Dubowsky and Alosco, Michael Louis and Apostolova, Liana G. and Bakulski, Kelly M. and Barnes, Lisa Laverne and others},
  title   = {{The Neighborhoods Study: Examining the social exposome in Alzheimer's disease and related dementias}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70810},
  pmid    = {41230793},
  url     = {https://doi.org/10.1002/alz.70810}
}

@article{ju2025-40098380,
  author  = {Ju, Eunae and Guo, Yuqing and Park, Jung In and Kim, Julie and Qu, Annie and Lee, Jung‐Ah},
  title   = {{Sleep Quality of Persons with Dementia and Family Caregivers in Korean Americans: Wearable Technology to Study the Dyadic Association}},
  journal = {Western Journal of Nursing Research},
  year    = {2025},
  doi     = {10.1177/01939459251323675},
  pmid    = {40098380},
  url     = {https://doi.org/10.1177/01939459251323675}
}

@article{kapoor2025-40034682,
  author  = {Kapoor, Arunima and Dutt, Shubir and Nguyen, Amy and Lohman, Trevor and Gaubert, Aimée and Alitin, John Paul M and Sible, Isabel J. and Marshall, Anisa J. and others},
  title   = {{Endothelial progenitor cells and cerebral small vessel disease in APOE4 carriers}},
  journal = {Cerebral Circulation - Cognition and Behavior},
  year    = {2025},
  doi     = {10.1016/j.cccb.2025.100378},
  pmid    = {40034682},
  url     = {https://doi.org/10.1016/j.cccb.2025.100378}
}

@article{lemoine2020-33222700,
  author  = {Lemoine, L. and Ledreux, A. and Mufson, E. J. and Perez, S. E. and Simic, G. and Doran, E. and Lott, I. and Carroll, S. and others},
  title   = {{Regional binding of tau and amyloid PET tracers in Down syndrome autopsy brain tissue}},
  journal = {Molecular neurodegeneration},
  year    = {2020},
  doi     = {10.1186/s13024-020-00414-3},
  pmid    = {33222700},
  url     = {https://doi.org/10.1186/s13024-020-00414-3}
}

@article{lauterborn2020-31410926,
  author  = {Lauterborn, J. C. and Cox, C. D. and Chan, S. W. and Vanderklish, P. W. and Lynch, G. and Gall, C. M.},
  title   = {{Synaptic actin stabilization protein loss in Down syndrome and Alzheimer disease}},
  journal = {Brain pathology (Zurich, Switzerland)},
  year    = {2020},
  doi     = {10.1111/bpa.12779},
  pmid    = {31410926},
  url     = {https://doi.org/10.1111/bpa.12779}
}

@article{raver2024-38443911,
  author  = {Raver, Eli and Xu, Wendy and Jung, Jeah Kyoungrae and Lee, Sunmin},
  title   = {{Breast cancer screening among Medicare Advantage enrollees with dementia}},
  journal = {BMC Health Services Research},
  year    = {2024},
  doi     = {10.1186/s12913-024-10740-7},
  pmid    = {38443911},
  url     = {https://doi.org/10.1186/s12913-024-10740-7}
}

@article{flemingbatayneh2026-42244445,
  author  = {Fleming-Batayneh, V. L. and Helsel, B. C. and Ptomey, L. T. and Handen, B. L. and Mapstone, M. and Petersen, M. and Krinsky-McHale, S. J. and Hom, C. L. and others},
  title   = {{Inflammation Associated With Obesity, Aging, and Amyloid Burden in Adults With Down Syndrome}},
  journal = {Obesity (Silver Spring, Md.)},
  year    = {2026},
  doi     = {10.1002/oby.70229},
  pmid    = {42244445},
  url     = {https://doi.org/10.1002/oby.70229}
}

@article{zhu2022-e6610b7d,
  author  = {Zhu, Yachen and Shi, Yuxi Vania and Manson, Spero M. and O’Connell, Joan M. and Jiang, Luohua},
  title   = {{Air pollution and dementia using longitudinal electronic health record data from the Indian Health Service}},
  journal = {Alzheimer s \& Dementia},
  year    = {2022},
  doi     = {10.1002/alz.067256},
  url     = {https://doi.org/10.1002/alz.067256}
}

@article{lott2006-19595881,
  author  = {Lott, I. T. and Doran, E. and Walsh, D. M. and Hill, M. A.},
  title   = {{Telemedicine, dementia and Down syndrome: implications for Alzheimer disease}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2006},
  doi     = {10.1016/j.jalz.2006.04.001},
  pmid    = {19595881},
  url     = {https://doi.org/10.1016/j.jalz.2006.04.001}
}

@article{reeves2019-30800043,
  author  = {Reeves, R. H. and Delabar, J. and Potier, M. C. and Bhattacharyya, A. and Head, E. and Lemere, C. and Dekker, A. D. and De Deyn, P. and others},
  title   = {{Paving the Way for Therapy: The Second International Conference of the Trisomy 21 Research Society}},
  journal = {Molecular syndromology},
  year    = {2019},
  doi     = {10.1159/000494231},
  pmid    = {30800043},
  url     = {https://doi.org/10.1159/000494231}
}

@article{head2009-18006193,
  author  = {Head, E. and Corrada, M. M. and Kahle-Wrobleski, K. and Kim, R. C. and Sarsoza, F. and Goodus, M. and Kawas, C. H.},
  title   = {{Synaptic proteins, neuropathology and cognitive status in the oldest-old}},
  journal = {Neurobiology of aging},
  year    = {2009},
  doi     = {10.1016/j.neurobiolaging.2007.10.001},
  pmid    = {18006193},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2007.10.001}
}

@article{taylor2025-41434168,
  author  = {Taylor, Lisa M. and Adams, Jenna N. and DiProspero, Natalie D. and McMillan, Liv C. and Sathishkumar, Mithra T. and Doran, Eric W. and Lai, Florence Y. and Rosas, H. Diana and others},
  title   = {{Functional connectivity differences in the default mode and frontoparietal networks in older adults with Down syndrome are related to obstructive sleep apnea}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70862_110032},
  pmid    = {41434168},
  url     = {https://doi.org/10.1002/alz70862_110032}
}

@article{liou2025-41453185,
  author  = {Liou, Jr‐Jiun and Santini, Tales and Ikonomović, Miloš D. and Villemagne, Victor L. and Cohen, Ann D. and Laymon, Charles M. and Minhas, Davneet Singh and Luo, Weiquan and others},
  title   = {{Correlating antemortem amyloid PET burden, postmortem MRI volumes, with neuropathological measures: Insights from Down syndrome and Alzheimer's disease cohorts}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70856_103737},
  pmid    = {41453185},
  url     = {https://doi.org/10.1002/alz70856_103737}
}

@article{dick2016-26704220,
  author  = {Dick, M. B. and Doran, E. and Phelan, M. and Lott, I. T.},
  title   = {{Cognitive Profiles on the Severe Impairment Battery Are Similar in Alzheimer Disease and Down Syndrome With Dementia}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2016},
  doi     = {10.1097/wad.0000000000000132},
  pmid    = {26704220},
  url     = {https://doi.org/10.1097/wad.0000000000000132}
}

@article{you2025-ef8594f7,
  author  = {You, Seungsook and Nguyen, Danh V. and Zisman‐Ilani, Yaara and Kovesdy, Csaba Pal and Crowley, Susan T. and Mukamel, Dana B. and Vargas, Alejandra Novoa and Narasaki, Yoko and others},
  title   = {{Impact of Conservative Management vs. Dialysis Transition on Cognition in a National Cohort of Patients with Advanced CKD}},
  journal = {Journal of the American Society of Nephrology},
  year    = {2025},
  doi     = {10.1681/asn.2025384tq669},
  url     = {https://doi.org/10.1681/asn.2025384tq669}
}

@article{amiri2023-37141452,
  author  = {Amiri, Solmaz and Jiang, Luohua and Manson, Spero M. and Buchwald, Dedra},
  title   = {{Trends in Alzheimer Disease Mortality Among American Indian and Alaska Native People Between 2011 and 2019}},
  journal = {Alzheimer Disease \& Associated Disorders},
  year    = {2023},
  doi     = {10.1097/wad.0000000000000555},
  pmid    = {37141452},
  url     = {https://doi.org/10.1097/wad.0000000000000555}
}

@article{taylor2025-ac6f6260,
  author  = {Taylor, Lisa M. and Adams, Jenna N. and DiProspero, Natalie D. and McMillan, Liv C. and Sathishkumar, Mithra T. and Doran, Eric W. and Lai, Florence Y. and Rosas, H. Diana and others},
  title   = {{Functional connectivity differences in the default mode and frontoparietal networks in older adults with Down syndrome are related to obstructive sleep apnea}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70856_105803},
  url     = {https://doi.org/10.1002/alz70856_105803}
}

@article{lemoine2020-a970244c,
  author  = {Lemoine, L. and Ledreux, A. and Mufson, E. J. and Perez, S. E. and Simic, G. and Doran, E. and Lott, I. and Carroll, S. and others},
  title   = {{Regional binding of tau and amyloid PET tracers in Down Syndrome autopsy brain tissue}},
  journal = {Molecular neurodegeneration},
  year    = {2020},
  doi     = {10.21203/rs.3.rs-48040/v2},
  url     = {https://doi.org/10.21203/rs.3.rs-48040/v2}
}

@article{yang2024-415a2d4f,
  author  = {Yang, Manxi and Abdulsalam, Ruqoyat and Adjei‐Boateng, Richard and Li, Lingling and Manson, Spero M. and O’Connell, Joan M. and Jiang, Luohua},
  title   = {{Associations between Social Determinants of Health and Alzheimer’s Disease and Related Dementia among American Indian and Alaska Native and White Medicare Beneficiaries}},
  journal = {Alzheimer s \& Dementia},
  year    = {2024},
  doi     = {10.1002/alz.092107},
  url     = {https://doi.org/10.1002/alz.092107}
}

@article{nguyen2026-42660657,
  author  = {Nguyen, Ann M. and Lo, Helen and Fields, James and Cramer, Karina S. and Zeng, Fan‐Gang and Dong, Wei and Xu, Xiangmin},
  title   = {{Temporal progression of auditory brainstem dysfunction and behavioral phenotypes in mouse models of tauopathy}},
  journal = {Journal of Neuroscience},
  year    = {2026},
  doi     = {10.1523/jneurosci.0511-26.2026},
  pmid    = {42660657},
  url     = {https://doi.org/10.1523/jneurosci.0511-26.2026}
}

@article{grill2025-39893378,
  author  = {Grill, Joshua D. and Gillen, Daniel L.},
  title   = {{Effects of intensive lifestyle changes on the progression of mild cognitive impairment or early dementia due to Alzheimer’s disease: the need for rigor}},
  journal = {Alzheimer s Research \& Therapy},
  year    = {2025},
  doi     = {10.1186/s13195-024-01621-6},
  pmid    = {39893378},
  url     = {https://doi.org/10.1186/s13195-024-01621-6}
}

@article{doherty2022-35622461,
  author  = {Doherty, T. and Gee, M. and Maruff, P. and Smith, R. and Murphy, J. and Marsh, J. and Koschalka, L. and Martinez, M. and others},
  title   = {{Increasing the Cognitive Screening Efficiency of Global Phase III Trials in Early Alzheimer Disease: The Cognitive Task Force}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2022},
  doi     = {10.1097/wad.0000000000000508},
  pmid    = {35622461},
  url     = {https://doi.org/10.1097/wad.0000000000000508}
}

@article{shaw2026-7f993fc1,
  author  = {Shaw, Ashley R. and Perales‐Puchalt, Jaime and Sandoval, Rachel and Glover, Crystal M. and Berkley‐Patton, Jannette and Vidoni, Eric D. and Burns, Jeffrey Murray},
  title   = {{Co-Developing a Culturally Tailored Dietary Intervention for ADRD Risk Reduction Using a Community-Based Research Approach: The MIND+SOUL Program}},
  journal = {Journal of Participatory Research Methods},
  year    = {2026},
  doi     = {10.35844/001c.141305},
  url     = {https://doi.org/10.35844/001c.141305}
}

@article{abdulsalam2023-94e9d0a1,
  author  = {Abdulsalam, Ruqoyat and O’Connell, Joan M. and Jiang, Luohua and Grau, Laura},
  title   = {{The relationship between social determinants of health and hospitalization among American Indian and Alaska native older adults with and without dementia}},
  journal = {Alzheimer s \& Dementia},
  year    = {2023},
  doi     = {10.1002/alz.068238},
  url     = {https://doi.org/10.1002/alz.068238}
}

@article{kim2025-40071594,
  author  = {Kim, JinShil and Cho, KyungAh and Hwang, Yoon Young and Lee, Jung‐Ah and Baek, Sang Yi and Yang, Jisun and Park, Yoonji and Heo, Seongkum},
  title   = {{Beliefs and attitudes of family caregivers of People with dementia toward advance care planning: A Q methodology study}},
  journal = {Dementia},
  year    = {2025},
  doi     = {10.1177/14713012251326463},
  pmid    = {40071594},
  url     = {https://doi.org/10.1177/14713012251326463}
}

@article{law2026-75b8b974,
  author  = {Law, Kevin W. and Engstrom, Allison C and Lohman, Trevor and Johnson, Melanie and Kapoor, Arunima and Alitin, John Paul M and Wang, Danny J.J. and Gaubert, Aimée and others},
  title   = {{Older adults in more disadvantaged neighborhoods exhibit brain vascular dysfunction}},
  journal = {Cerebral Circulation - Cognition and Behavior},
  year    = {2026},
  doi     = {10.1016/j.cccb.2026.100562},
  url     = {https://doi.org/10.1016/j.cccb.2026.100562}
}

@article{guirgishely2026-eb95fab7,
  author  = {Guirgis Hely, M.},
  title   = {{The Cost of Alzheimer Drug Treatment}},
  journal = {Zenodo (CERN European Organization for Nuclear Research)},
  year    = {2026},
  doi     = {10.5281/zenodo.18531026},
  url     = {https://doi.org/10.5281/zenodo.18531026}
}

@article{crouzet2025-ff920d55,
  author  = {Crouzet, Christian and Liu, Jihua and Choi, Bernard and Cribbs, David H},
  title   = {{A Novel Mouse Model for Investigating ARIAs in Response to Anti-Abeta Immunotherapy}},
  journal = {Cerebral Circulation - Cognition and Behavior},
  year    = {2025},
  doi     = {10.1016/j.cccb.2025.100475},
  url     = {https://doi.org/10.1016/j.cccb.2025.100475}
}

@article{guirgis2025-2f85dd17,
  author  = {Guirgis, Helmy M.},
  title   = {{The Cost of Alzheimer Drug Treatment}},
  journal = {Medical Research Archives},
  year    = {2025},
  doi     = {10.18103/mra.v14i1.7163},
  url     = {https://doi.org/10.18103/mra.v14i1.7163}
}

@article{karim2026-9885f5da,
  author  = {Karim, F. and Chavez-Jacobo, N. P. and Liang, C. and Head, E. and Mukherjee, J.},
  title   = {{Down syndrome postmortem brains exhibit reduction in [ 18 F]nifene binding to α4β2* nicotinic acetylcholinergic receptors}},
  journal = {bioRxiv},
  year    = {2026},
  doi     = {10.64898/2026.09.09.750420},
  url     = {https://doi.org/10.64898/2026.09.09.750420}
}

@article{song2026-c369392a,
  author  = {Song, Z. and Song, S. and Clare, I. C. and Head, E. and Hom, C. L. and Brickman, A. M. and Hartley, S. and Lao, P. J. and others},
  title   = {{Multi-dimensional attention framework for personalised Alzheimer's disease progression prediction across sporadic and genetic risk cohorts}},
  journal = {Research Square},
  year    = {2026},
  doi     = {10.21203/rs.3.rs-10309496/v1},
  url     = {https://doi.org/10.21203/rs.3.rs-10309496/v1}
}

@article{schworer2024-f00bce0d,
  author  = {Schworer, E. K. and Zammit, M. D. and Wang, J. and Handen, B. L. and Betthauser, T. and Laymon, C. M. and Tudorascu, D. L. and Cohen, A. D. and others},
  title   = {{Amyloid age and tau PET timeline to symptomatic Alzheimer’s disease in Down syndrome}},
  journal = {medRxiv},
  year    = {2024},
  doi     = {10.1101/2024.08.08.24311702},
  url     = {https://doi.org/10.1101/2024.08.08.24311702}
}

@article{edwards2023-e40cb7d2,
  author  = {Edwards, N. C. and Lao, P. J. and Alshikho, M. J. and Ericsson, O. M. and Rizvi, B. and Petersen, M. E. and O’Bryant, S. and Flores-Aguilar, L. and others},
  title   = {{Cerebrovascular disease drives Alzheimer plasma biomarker concentrations in adults with Down syndrome}},
  journal = {medRxiv},
  year    = {2023},
  doi     = {10.1101/2023.11.28.23298693},
  url     = {https://doi.org/10.1101/2023.11.28.23298693}
}