% alzhub.org library filter % Source: https://alzhub.org/research?institution=I188891513 % 27 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{kaul2001-11309629, author = {Kaul, M. and Garden, G. A. and Lipton, S. A.}, title = {{Pathways to neuronal injury and apoptosis in HIV-associated dementia}}, journal = {Nature}, year = {2001}, doi = {10.1038/35073667}, pmid = {11309629}, url = {https://doi.org/10.1038/35073667} } @article{zhao2018-29518356, author = {Zhao, Y. and Wu, X. and Li, X. and Jiang, L. L. and Gui, X. and Liu, Y. and Sun, Y. and Zhu, B. and others}, title = {{TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function}}, journal = {Neuron}, year = {2018}, doi = {10.1016/j.neuron.2018.01.031}, pmid = {29518356}, url = {https://doi.org/10.1016/j.neuron.2018.01.031} } @article{zhong2019-30911003, author = {Zhong, L. and Xu, Y. and Zhuo, R. and Wang, T. and Wang, K. and Huang, R. and Wang, D. and Gao, Y. and others}, title = {{Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model}}, journal = {Nature communications}, year = {2019}, doi = {10.1038/s41467-019-09118-9}, pmid = {30911003}, url = {https://doi.org/10.1038/s41467-019-09118-9} } @article{toledo2017-28341160, author = {Toledo, J. B. and Arnold, M. and Kastenmüller, G. and Chang, R. and Baillie, R. A. and Han, X. and Thambisetty, M. and Tenenbaum, J. D. and others}, title = {{Metabolic network failures in Alzheimer's disease: A biochemical road map}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2017}, doi = {10.1016/j.jalz.2017.01.020}, pmid = {28341160}, url = {https://doi.org/10.1016/j.jalz.2017.01.020} } @article{zhong2017-28209725, author = {Zhong, L. and Chen, X. F. and Wang, T. and Wang, Z. and Liao, C. and Huang, R. and Wang, D. and others}, title = {{Soluble TREM2 induces inflammatory responses and enhances microglial survival}}, journal = {The Journal of experimental medicine}, year = {2017}, doi = {10.1084/jem.20160844}, pmid = {28209725}, url = {https://doi.org/10.1084/jem.20160844} } @article{ganguly2024-39172787, author = {Ganguly, S. and Rosenthal, S. B. and Ishizuka, K. and Troutman, T. D. and Rohm, T. V. and Khader, N. and Aleman-Muench, G. and Sano, Y. and others}, title = {{Lipid-associated macrophages' promotion of fibrosis resolution during MASH regression requires TREM2}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2024}, doi = {10.1073/pnas.2405746121}, pmid = {39172787}, url = {https://doi.org/10.1073/pnas.2405746121} } @article{guo2020-32677986, author = {Guo, T. and Zhang, D. and Zeng, Y. and Huang, T. Y. and Xu, H. and Zhao, Y.}, title = {{Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer's disease}}, journal = {Molecular neurodegeneration}, year = {2020}, doi = {10.1186/s13024-020-00391-7}, pmid = {32677986}, url = {https://doi.org/10.1186/s13024-020-00391-7} } @article{lee2018-29518357, author = {Lee, C. Y. D. and Daggett, A. and Gu, X. and Jiang, L. L. and Langfelder, P. and Li, X. and Wang, N. and Zhao, Y. and others}, title = {{Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models}}, journal = {Neuron}, year = {2018}, doi = {10.1016/j.neuron.2018.02.002}, pmid = {29518357}, url = {https://doi.org/10.1016/j.neuron.2018.02.002} } @article{zhang2007-17303576, author = {Zhang, X. and Zhou, K. and Wang, R. and Cui, J. and Lipton, S. A. and Liao, F. F. and Xu, H. and Zhang, Y. W.}, title = {{Hypoxia-inducible factor 1alpha (HIF-1alpha)-mediated hypoxia increases BACE1 expression and beta-amyloid generation}}, journal = {The Journal of biological chemistry}, year = {2007}, doi = {10.1074/jbc.m608856200}, pmid = {17303576}, url = {https://doi.org/10.1074/jbc.m608856200} } @article{zheng2017-28077724, author = {Zheng, H. and Jia, L. and Liu, C. C. and Rong, Z. and Zhong, L. and Yang, L. and Chen, X. F. and Fryer, J. D. and others}, title = {{TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2017}, doi = {10.1523/jneurosci.2459-16.2017}, pmid = {28077724}, url = {https://doi.org/10.1523/jneurosci.2459-16.2017} } @article{zhao2022-36070367, author = {Zhao, P. and Xu, Y. and Jiang, L. and Fan, X. and Li, L. and Li, X. and Arase, H. and Zhao, Y. and others}, title = {{A tetravalent TREM2 agonistic antibody reduced amyloid pathology in a mouse model of Alzheimer's disease}}, journal = {Science translational medicine}, year = {2022}, doi = {10.1126/scitranslmed.abq0095}, pmid = {36070367}, url = {https://doi.org/10.1126/scitranslmed.abq0095} } @article{fang2019-31272829, author = {Fang, M. Y. and Markmiller, S. and Vu, A. Q. and Javaherian, A. and Dowdle, W. E. and Jolivet, P. and Bushway, P. J. and Castello, N. A. and others}, title = {{Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD}}, journal = {Neuron}, year = {2019}, doi = {10.1016/j.neuron.2019.05.048}, pmid = {31272829}, url = {https://doi.org/10.1016/j.neuron.2019.05.048} } @article{zhong2018-29587871, author = {Zhong, L. and Wang, Z. and Wang, D. and Martens, Y. A. and Wu, L. and Xu, Y. and Wang, K. and others}, title = {{Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2)}}, journal = {Molecular neurodegeneration}, year = {2018}, doi = {10.1186/s13024-018-0247-7}, pmid = {29587871}, url = {https://doi.org/10.1186/s13024-018-0247-7} } @article{liu2020-32941599, author = {Liu, T. and Zhu, B. and Liu, Y. and Zhang, X. and Yin, J. and Li, X. and Jiang, L. and Hodges, A. P. and others}, title = {{Multi-omic comparison of Alzheimer's variants in human ESC-derived microglia reveals convergence at APOE}}, journal = {The Journal of experimental medicine}, year = {2020}, doi = {10.1084/jem.20200474}, pmid = {32941599}, url = {https://doi.org/10.1084/jem.20200474} } @article{shinohara2016-26933942, author = {Shinohara, M. and Kanekiyo, T. and Yang, L. and Linthicum, D. and Fu, Y. and Price, L. and Frisch-Daiello, J. L. and others}, title = {{APOE2 eases cognitive decline during Aging: Clinical and preclinical evaluations}}, journal = {Annals of neurology}, year = {2016}, doi = {10.1002/ana.24628}, pmid = {26933942}, url = {https://doi.org/10.1002/ana.24628} } @article{zhu2022-36056435, author = {Zhu, B. and Liu, Y. and Hwang, S. and Archuleta, K. and Huang, H. and Campos, A. and Murad, R. and Piña-Crespo, J. and others}, title = {{Trem2 deletion enhances tau dispersion and pathology through microglia exosomes}}, journal = {Molecular neurodegeneration}, year = {2022}, doi = {10.1186/s13024-022-00562-8}, pmid = {36056435}, url = {https://doi.org/10.1186/s13024-022-00562-8} } @article{zheng2016-27143430, author = {Zheng, H. and Liu, C. C. and Atagi, Y. and Chen, X. F. and Jia, L. and Yang, L. and He, W. and Zhang, X. and others}, title = {{Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation}}, journal = {Neurobiology of aging}, year = {2016}, doi = {10.1016/j.neurobiolaging.2016.03.004}, pmid = {27143430}, url = {https://doi.org/10.1016/j.neurobiolaging.2016.03.004} } @article{zhong2015-25957402, author = {Zhong, L. and Chen, X. F. and Zhang, Z. L. and Wang, Z. and Shi, X. Z. and Xu, K. and Zhang, Y. W. and Xu, H. and others}, title = {{DAP12 Stabilizes the C-terminal Fragment of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) and Protects against LPS-induced Pro-inflammatory Response}}, journal = {The Journal of biological chemistry}, year = {2015}, doi = {10.1074/jbc.m115.645986}, pmid = {25957402}, url = {https://doi.org/10.1074/jbc.m115.645986} } @article{nam2017-28655926, author = {Nam, K. N. and Mounier, A. and Wolfe, C. M. and Fitz, N. F. and Carter, A. Y. and Castranio, E. L. and Kamboh, H. I. and Reeves, V. L. and others}, title = {{Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer's model mice}}, journal = {Scientific reports}, year = {2017}, doi = {10.1038/s41598-017-04412-2}, pmid = {28655926}, url = {https://doi.org/10.1038/s41598-017-04412-2} } @article{zhao2022-35717259, author = {Zhao, P. and Xu, Y. and Jiang, L. L. and Fan, X. and Ku, Z. and Li, L. and Liu, X. and Deng, M. and others}, title = {{LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions}}, journal = {Molecular neurodegeneration}, year = {2022}, doi = {10.1186/s13024-022-00550-y}, pmid = {35717259}, url = {https://doi.org/10.1186/s13024-022-00550-y} } @article{sun2011-21216952, author = {Sun, X. and Wu, Y. and Chen, B. and Zhang, Z. and Zhou, W. and Tong, Y. and Yuan, J. and Xia, K. and others}, title = {{Regulator of calcineurin 1 (RCAN1) facilitates neuronal apoptosis through caspase-3 activation}}, journal = {The Journal of biological chemistry}, year = {2011}, doi = {10.1074/jbc.m110.177519}, pmid = {21216952}, url = {https://doi.org/10.1074/jbc.m110.177519} } @article{vetrivel2006-16930451, author = {Vetrivel, K. S. and Zhang, Y. W. and Xu, H. and Thinakaran, G.}, title = {{Pathological and physiological functions of presenilins}}, journal = {Molecular neurodegeneration}, year = {2006}, doi = {10.1186/1750-1326-1-4}, pmid = {16930451}, url = {https://doi.org/10.1186/1750-1326-1-4} } @article{zhang2005-15711015, author = {Zhang, Y. W. and Luo, W. J. and Wang, H. and Lin, P. and Vetrivel, K. S. and Liao, F. and Li, F. and Wong, P. C. and others}, title = {{Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components}}, journal = {The Journal of biological chemistry}, year = {2005}, doi = {10.1074/jbc.m409467200}, pmid = {15711015}, url = {https://doi.org/10.1074/jbc.m409467200} } @article{zhong2017-28680398, author = {Zhong, L. and Zhang, Z. L. and Li, X. and Liao, C. and Mou, P. and Wang, T. and Wang, Z. and others}, title = {{TREM2/DAP12 Complex Regulates Inflammatory Responses in Microglia via the JNK Signaling Pathway}}, journal = {Frontiers in aging neuroscience}, year = {2017}, doi = {10.3389/fnagi.2017.00204}, pmid = {28680398}, url = {https://doi.org/10.3389/fnagi.2017.00204} } @article{wang2006-16645044, author = {Wang, R. and Zhang, Y. W. and Zhang, X. and Liu, R. and Hong, S. and Xia, K. and Xia, J. and others}, title = {{Transcriptional regulation of APH-1A and increased gamma-secretase cleavage of APP and Notch by HIF-1 and hypoxia}}, journal = {FASEB journal : official publication of the Federation of American Societies for Experimental Biology}, year = {2006}, doi = {10.1096/fj.06-5839fje}, pmid = {16645044}, url = {https://doi.org/10.1096/fj.06-5839fje} } @article{dodd2026-40766450, author = {Dodd, Roger B. and Enomoto, Masahiro and Zhou, Ye and Satoh, Kanayo and Zhang, Yalun and Chen, Fusheng and Acheson, Beatrice and Ghaffari, Deniz and others}, title = {{CD33 and clusterin interact biophysically and genetically to modulate Alzheimer risk}}, journal = {Nature Communications}, year = {2026}, doi = {10.1038/s41467-026-75140-3}, pmid = {40766450}, url = {https://doi.org/10.1038/s41467-026-75140-3} } @article{dodd2026-c8ae3fc8, author = {Dodd, Roger B. and Enomoto, Masahiro and Zhou, Ye and Satoh, Kanayo and Zhang, Yalun and Chen, Fusheng and Acheson, Beatrice and Ghaffari, Deniz and others}, title = {{CD33 and clusterin interact biophysically and genetically to modulate Alzheimer risk}}, journal = {DOAJ (DOAJ: Directory of Open Access Journals)}, year = {2026}, doi = {10.1038/s41467-026-75140-3}, url = {https://doi.org/10.1038/s41467-026-75140-3} }