% alzhub.org library filter % Source: https://alzhub.org/research?institution=I136199984 % 500 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{barnes2023-37466280, author = {Barnes, L. L. and Dhana, K. and Liu, X. and Carey, V. J. and Ventrelle, J. and Johnson, K. and others}, title = {{Trial of the MIND Diet for Prevention of Cognitive Decline in Older Persons}}, journal = {New England Journal of Medicine}, year = {2023}, doi = {10.1056/NEJMoa2302368}, pmid = {37466280}, url = {https://doi.org/10.1056/NEJMoa2302368} } @article{kunkle2019-30820047, author = {Kunkle, B. W. and Grenier-Boley, B. and Sims, R. and Bis, J. C. and Damotte, V. and Naj, A. C. and Boland, A. and Vronskaya, M. and others}, title = {{Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing}}, journal = {Nature genetics}, year = {2019}, doi = {10.1038/s41588-019-0358-2}, pmid = {30820047}, url = {https://doi.org/10.1038/s41588-019-0358-2} } @article{zimmer2025-40063015, author = {Zimmer, J. A. and Ardayfio, P. and Wang, H. and Khanna, R. and Evans, C. D. and Lu, M. and Sparks, J. and Andersen, S. and Lauzon, S. and Nery, E. S. M. and others}, title = {{Amyloid-Related Imaging Abnormalities With Donanemab in Early Symptomatic Alzheimer Disease: Secondary Analysis of the TRAILBLAZER-ALZ and ALZ 2 Randomized Clinical Trials}}, journal = {JAMA Neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.0065}, pmid = {40063015}, url = {https://doi.org/10.1001/jamaneurol.2025.0065} } @article{naj2011-21460841, author = {Naj, A. C. and Jun, G. and Beecham, G. W. and Wang, L. S. and Vardarajan, B. N. and Buros, J. and Gallins, P. J. and Buxbaum, J. D. and others}, title = {{Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease}}, journal = {Nature genetics}, year = {2011}, doi = {10.1038/ng.801}, pmid = {21460841}, url = {https://doi.org/10.1038/ng.801} } @article{wolters2020-32611641, author = {Wolters, F. J. and Chibnik, L. B. and Waziry, R. and Anderson, R. and Berr, C. and Beiser, A. and Bis, J. C. and Blacker, D. and others}, title = {{Twenty-seven-year time trends in dementia incidence in Europe and the United States: The Alzheimer Cohorts Consortium}}, journal = {Neurology}, year = {2020}, doi = {10.1212/wnl.0000000000010022}, pmid = {32611641}, url = {https://doi.org/10.1212/wnl.0000000000010022} } @article{florian2023-36730056, author = {Florian, H. and Wang, D. and Arnold, S. E. and Boada, M. and Guo, Q. and Jin, Z. and Zheng, H. and Fisseha, N. and others}, title = {{Tilavonemab in early Alzheimer's disease: results from a phase 2, randomized, double-blind study}}, journal = {Brain : a journal of neurology}, year = {2023}, doi = {10.1093/brain/awad024}, pmid = {36730056}, url = {https://doi.org/10.1093/brain/awad024} } @article{chen2023-37133875, author = {Chen, H. and Dhana, K. and Huang, Y. and Huang, L. and Tao, Y. and Liu, X. and others}, title = {{Association of the Mediterranean Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diet With the Risk of Dementia}}, journal = {JAMA Psychiatry}, year = {2023}, doi = {10.1001/jamapsychiatry.2023.0800}, pmid = {37133875}, url = {https://doi.org/10.1001/jamapsychiatry.2023.0800} } @article{ostrowitzki2022-36121669, author = {Ostrowitzki, S. and Bittner, T. and Sink, K. M. and Mackey, H. and Rabe, C. and Honig, L. S. and Cassetta, E. and Woodward, M. and others}, title = {{Evaluating the Safety and Efficacy of Crenezumab vs Placebo in Adults With Early Alzheimer Disease: Two Phase 3 Randomized Placebo-Controlled Trials}}, journal = {JAMA neurology}, year = {2022}, doi = {10.1001/jamaneurol.2022.2909}, pmid = {36121669}, url = {https://doi.org/10.1001/jamaneurol.2022.2909} } @article{moayyedi2019-31152740, author = {Moayyedi, P. and Eikelboom, J. W. and Bosch, J. and Connolly, S. J. and Dyal, L. and Shestakovska, O. and Leong, D. and Anand, S. S. and others}, title = {{Safety of Proton Pump Inhibitors Based on a Large, Multi-Year, Randomized Trial of Patients Receiving Rivaroxaban or Aspirin}}, journal = {Gastroenterology}, year = {2019}, doi = {10.1053/j.gastro.2019.05.056}, pmid = {31152740}, url = {https://doi.org/10.1053/j.gastro.2019.05.056} } @article{cummings2025-39780249, author = {Cummings, J. L. and Atri, A. and Feldman, H. H. and Hansson, O. and Sano, M. and Knop, F. K. and Johannsen, P. and León, T. and others}, title = {{evoke and evoke+: design of two large-scale, double-blind, placebo-controlled, phase 3 studies evaluating efficacy, safety, and tolerability of semaglutide in early-stage symptomatic Alzheimer's disease}}, journal = {Alzheimer's research \& therapy}, year = {2025}, doi = {10.1186/s13195-024-01666-7}, pmid = {39780249}, url = {https://doi.org/10.1186/s13195-024-01666-7} } @article{manson2013-24084921, author = {Manson, J. E. and Chlebowski, R. T. and Stefanick, M. L. and Aragaki, A. K. and Rossouw, J. E. and Prentice, R. L. and Anderson, G. and Howard, B. V. and others}, title = {{Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the Women's Health Initiative randomized trials}}, journal = {JAMA}, year = {2013}, doi = {10.1001/jama.2013.278040}, pmid = {24084921}, url = {https://doi.org/10.1001/jama.2013.278040} } @article{pase2023-37462968, author = {Pase, M. P. and Harrison, S. and Misialek, JR. and Kline, C. E. and Cavuoto, M. and Baril, A. A. and Yiallourou, S. and Bisson, A. and others}, title = {{Sleep Architecture, Obstructive Sleep Apnea, and Cognitive Function in Adults}}, journal = {JAMA network open}, year = {2023}, doi = {10.1001/jamanetworkopen.2023.25152}, pmid = {37462968}, url = {https://doi.org/10.1001/jamanetworkopen.2023.25152} } @article{bouzid2023-37322115, author = {Bouzid, H. and Belk, J. A. and Jan, M. and Qi, Y. and Sarnowski, C. and Wirth, S. and Ma, L. and Chrostek, M. R. and others}, title = {{Clonal hematopoiesis is associated with protection from Alzheimer's disease}}, journal = {Nature medicine}, year = {2023}, doi = {10.1038/s41591-023-02397-2}, pmid = {37322115}, url = {https://doi.org/10.1038/s41591-023-02397-2} } @article{blazhenets2026-42441390, author = {Blazhenets, Ganna and Soleimani-Meigooni, David N and Chiotis, Konstantinos and Allen, Isabel E and Rabinovici, Gil D and La Joie, Renaud and {Meta-Centiloid Study Group} and Apostolova, Liana G and others}, title = {{Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis}}, journal = {JAMA}, year = {2026}, doi = {10.1001/jama.2026.13116}, pmid = {42441390}, url = {https://doi.org/10.1001/jama.2026.13116} } @article{jun2016-25778476, author = {Jun, G. and Ibrahim-Verbaas, C. A. and Vronskaya, M. and Lambert, J. C. and Chung, J. and Naj, A. C. and Kunkle, B. W. and Wang, L. S. and others}, title = {{A novel Alzheimer disease locus located near the gene encoding tau protein}}, journal = {Molecular psychiatry}, year = {2016}, doi = {10.1038/mp.2015.23}, pmid = {25778476}, url = {https://doi.org/10.1038/mp.2015.23} } @article{bateman2012-22784036, author = {Bateman, Randall John and Xiong, Chengjie and Benzinger, Tammie L.S. and Fagan, Anne M. and Goate, Alison and Fox, Nick C. and Marcus, Daniel S. and Cairns, Nigel J. and others}, title = {{Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease}}, journal = {New England Journal of Medicine}, year = {2012}, doi = {10.1056/nejmoa1202753}, pmid = {22784036}, url = {https://doi.org/10.1056/nejmoa1202753} } @article{reitz2013-23571587, author = {Reitz, C. and Jun, G. and Naj, A. and Rajbhandary, R. and Vardarajan, B. N. and Wang, L. S. and Valladares, O. and Lin, C. F. and others}, title = {{Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans}}, journal = {JAMA}, year = {2013}, doi = {10.1001/jama.2013.2973}, pmid = {23571587}, url = {https://doi.org/10.1001/jama.2013.2973} } @article{honig2024-38730496, author = {Honig, L. S. and Sabbagh, M. N. and van Dyck, C. H. and Sperling, R. A. and Hersch, S. and Matta, A. and Giorgi, L. and Gee, M. and others}, title = {{Updated safety results from phase 3 lecanemab study in early Alzheimer's disease}}, journal = {Alzheimer's research \& therapy}, year = {2024}, doi = {10.1186/s13195-024-01441-8}, pmid = {38730496}, url = {https://doi.org/10.1186/s13195-024-01441-8} } @article{atri2018-29318278, author = {Atri, A. and Frölich, L. and Ballard, C. and Tariot, P. N. and Molinuevo, J. L. and Boneva, N. and Windfeld, K. and Raket, L. L. and others}, title = {{Effect of Idalopirdine as Adjunct to Cholinesterase Inhibitors on Change in Cognition in Patients With Alzheimer Disease: Three Randomized Clinical Trials}}, journal = {JAMA}, year = {2018}, doi = {10.1001/jama.2017.20373}, pmid = {29318278}, url = {https://doi.org/10.1001/jama.2017.20373} } @article{palmqvist2020-32722745, author = {Palmqvist, S. and Janelidze, S. and Quiroz, Y. T. and Zetterberg, H. and Lopera, F. and Stomrud, E. and Su, Y. and Chen, Y. and others}, title = {{Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders}}, journal = {JAMA}, year = {2020}, doi = {10.1001/jama.2020.12134}, pmid = {32722745}, url = {https://doi.org/10.1001/jama.2020.12134} } @article{hanseeuw2019-31157827, author = {Hanseeuw, B. J. and Betensky, R. A. and Jacobs, H. I. L. and Schultz, A. P. and Sepulcre, J. and Becker, J. A. and Cosio, D. M. O. and Farrell, M. and others}, title = {{Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease: A Longitudinal Study}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2019.1424}, pmid = {31157827}, url = {https://doi.org/10.1001/jamaneurol.2019.1424} } @article{gordon2018-29397305, author = {Gordon, B. A. and Blazey, T. M. and Su, Y. and Hari-Raj, A. and Dincer, A. and Flores, S. and Christensen, J. and McDade, E. and others}, title = {{Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study}}, journal = {The Lancet. Neurology}, year = {2018}, doi = {10.1016/s1474-4422(18)30028-0}, pmid = {29397305}, url = {https://doi.org/10.1016/s1474-4422(18)30028-0} } @article{sabbagh2020-31879235, author = {Sabbagh, M. and Sadowsky, C. and Tousi, B. and Agronin, M. E. and Alva, G. and Armon, C. and Bernick, C. and Keegan, A. P. and others}, title = {{Effects of a combined transcranial magnetic stimulation (TMS) and cognitive training intervention in patients with Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2020}, doi = {10.1016/j.jalz.2019.08.197}, pmid = {31879235}, url = {https://doi.org/10.1016/j.jalz.2019.08.197} } @article{rajabli2025-40676597, author = {Rajabli, F. and Benchek, P. and Tosto, G. and Kushch, N. and Sha, J. and Bazemore, K. and Zhu, C. and Lee, W. P. and others}, title = {{Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease}}, journal = {Genome biology}, year = {2025}, doi = {10.1186/s13059-025-03564-z}, pmid = {40676597}, url = {https://doi.org/10.1186/s13059-025-03564-z} } @article{wang2025-40172303, author = {Wang, H. and Serap Monkul Nery, E. and Ardayfio, P. and Khanna, R. and Otero Svaldi, D. and Gueorguieva, I. and Shcherbinin, S. and Andersen, S. W. and Hauck, P. M. and Engle, S. E. and others}, title = {{Modified titration of donanemab reduces ARIA risk and maintains amyloid reduction}}, journal = {Alzheimer's \& Dementia}, year = {2025}, doi = {10.1002/alz.70062}, pmid = {40172303}, url = {https://doi.org/10.1002/alz.70062} } @article{bertram2007-17192785, author = {Bertram, L. and McQueen, M. B. and Mullin, K. and Blacker, D. and Tanzi, R. E.}, title = {{Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database}}, journal = {Nature genetics}, year = {2007}, doi = {10.1038/ng1934}, pmid = {17192785}, url = {https://doi.org/10.1038/ng1934} } @article{bergeron2018-30255971, author = {Bergeron, D. and Gorno-Tempini, M. L. and Rabinovici, G. D. and Santos-Santos, M. A. and Seeley, W. and Miller, B. L. and Pijnenburg, Y. and Keulen, M. A. and others}, title = {{Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia}}, journal = {Annals of neurology}, year = {2018}, doi = {10.1002/ana.25333}, pmid = {30255971}, url = {https://doi.org/10.1002/ana.25333} } @article{coughlan2025-40029638, author = {Coughlan, G. T. and Klinger, H. M. and Boyle, R. and Betthauser, T. J. and Binette, A. P. and Christenson, L. and Chadwick, T. and Hansson, O. and others}, title = {{Sex Differences in Longitudinal Tau-PET in Preclinical Alzheimer Disease: A Meta-Analysis}}, journal = {JAMA neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.0013}, pmid = {40029638}, url = {https://doi.org/10.1001/jamaneurol.2025.0013} } @article{lee2023-36637034, author = {Lee, J. and Meijer, E. and Langa, K. M. and Ganguli, M. and Varghese, M. and Banerjee, J. and Khobragade, P. and Angrisani, M. and others}, title = {{Prevalence of dementia in India: National and state estimates from a nationwide study}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2023}, doi = {10.1002/alz.12928}, pmid = {36637034}, url = {https://doi.org/10.1002/alz.12928} } @article{ossenkoppele2022-36357681, author = {Ossenkoppele, R. and Pichet Binette, A. and Groot, C. and Smith, R. and Strandberg, O. and Palmqvist, S. and Stomrud, E. and Tideman, P. and others}, title = {{Amyloid and tau PET-positive cognitively unimpaired individuals are at high risk for future cognitive decline}}, journal = {Nature medicine}, year = {2022}, doi = {10.1038/s41591-022-02049-x}, pmid = {36357681}, url = {https://doi.org/10.1038/s41591-022-02049-x} } @article{moscoso2025-40522652, author = {Moscoso, Alexis and Heeman, Fiona and Raghavan, Sheelakumari and Costoya‐Sánchez, Alejandro and van Essen, Martijn and Mainta, Ismini and Camacho, Valle and Rodríguez-Fonseca, Omar Darío and others}, title = {{Frequency and Clinical Outcomes Associated With Tau Positron Emission Tomography Positivity}}, journal = {JAMA}, year = {2025}, doi = {10.1001/jama.2025.7817}, pmid = {40522652}, url = {https://doi.org/10.1001/jama.2025.7817} } @article{baker2025-40720610, author = {Baker, L. D. and Espeland, M. A. and Whitmer, R. A. and Snyder, H. M. and Leng, X. and Lovato, L. and Papp, K. V. and Yu, M. and others}, title = {{Structured vs Self-Guided Multidomain Lifestyle Interventions for Global Cognitive Function: The US POINTER Randomized Clinical Trial}}, journal = {JAMA}, year = {2025}, doi = {10.1001/jama.2025.12923}, pmid = {40720610}, url = {https://doi.org/10.1001/jama.2025.12923} } @article{sherva2023-36543923, author = {Sherva, R. and Zhang, R. and Sahelijo, N. and Jun, G. and Anglin, T. and Chanfreau, C. and Cho, K. and Fonda, JR. and others}, title = {{African ancestry GWAS of dementia in a large military cohort identifies significant risk loci}}, journal = {Molecular psychiatry}, year = {2023}, doi = {10.1038/s41380-022-01890-3}, pmid = {36543923}, url = {https://doi.org/10.1038/s41380-022-01890-3} } @article{mattssoncarlgren2020-33068398, author = {Mattsson-Carlgren, N. and Janelidze, S. and Palmqvist, S. and Cullen, N. and Svenningsson, A. L. and Strandberg, O. and Mengel, D. and Walsh, D. M. and others}, title = {{Longitudinal plasma p-tau217 is increased in early stages of Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2020}, doi = {10.1093/brain/awaa286}, pmid = {33068398}, url = {https://doi.org/10.1093/brain/awaa286} } @article{pottier2025-40280976, author = {Pottier, Cyril P. and Küçükali, Fahri and Baker, Matt C. and Batzler, Anthony and Jenkins, Gregory D. and van Blitterswijk, Marka and Vicente, Cristina T. and De Coster, Wouter and others}, title = {{Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing}}, journal = {Nature Communications}, year = {2025}, doi = {10.1038/s41467-025-59216-0}, pmid = {40280976}, url = {https://doi.org/10.1038/s41467-025-59216-0} } @article{rabinovici2025-39776249, author = {Rabinovici, G. D. and Knopman, D. S. and Arbizu, J. and Benzinger, T. L. S. and Donohoe, K. J. and Hansson, O. and Herscovitch, P. and Kuo, P. H. and Lingler, J. H. and Minoshima, S. and others}, title = {{Updated appropriate use criteria for amyloid and tau PET: A report from the Alzheimer's Association and Society for Nuclear Medicine and Molecular Imaging Workgroup}}, journal = {Alzheimer's \& Dementia}, year = {2025}, doi = {10.1002/alz.14338}, pmid = {39776249}, url = {https://doi.org/10.1002/alz.14338} } @article{preische2019-30664784, author = {Preische, O. and Schultz, S. A. and Apel, A. and Kuhle, J. and Kaeser, S. A. and Barro, C. and Gräber, S. and others}, title = {{Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer's disease}}, journal = {Nature medicine}, year = {2019}, doi = {10.1038/s41591-018-0304-3}, pmid = {30664784}, url = {https://doi.org/10.1038/s41591-018-0304-3} } @article{sperling2024-39044488, author = {Sperling, R. A. and Donohue, M. C. and Rissman, R. A. and Johnson, K. A. and Rentz, D. M. and Grill, J. D. and Heidebrink, J. L. and Jenkins, C. and others}, title = {{Amyloid and Tau Prediction of Cognitive and Functional Decline in Unimpaired Older Individuals: Longitudinal Data from the A4 and LEARN Studies}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2024}, doi = {10.14283/jpad.2024.122}, pmid = {39044488}, url = {https://doi.org/10.14283/jpad.2024.122} } @article{wagemann2024-38683602, author = {Wagemann, O. and Liu, H. and Wang, G. and Shi, X. and Bittner, T. and Scelsi, M. A. and Farlow, M. R. and Clifford, D. B. and others}, title = {{Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease: The DIAN-TU-001 Randomized Clinical Trial}}, journal = {JAMA neurology}, year = {2024}, doi = {10.1001/jamaneurol.2024.0991}, pmid = {38683602}, url = {https://doi.org/10.1001/jamaneurol.2024.0991} } @article{bodick1997-9109749, author = {Bodick, N. C. and Offen, W. W. and Levey, A. I. and Cutler, N. R. and Gauthier, S. G. and Satlin, A. and Shannon, H. E. and Tollefson, G. D. and others}, title = {{Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease}}, journal = {Archives of neurology}, year = {1997}, doi = {10.1001/archneur.1997.00550160091022}, pmid = {9109749}, url = {https://doi.org/10.1001/archneur.1997.00550160091022} } @article{grill2020-32777010, author = {Grill, J. D. and Raman, R. and Ernstrom, K. and Sultzer, D. L. and Burns, J. M. and Donohue, M. C. and Johnson, K. A. and Aisen, P. S. and others}, title = {{Short-term Psychological Outcomes of Disclosing Amyloid Imaging Results to Research Participants Who Do Not Have Cognitive Impairment}}, journal = {JAMA neurology}, year = {2020}, doi = {10.1001/jamaneurol.2020.2734}, pmid = {32777010}, url = {https://doi.org/10.1001/jamaneurol.2020.2734} } @article{ornish2024-38849944, author = {Ornish, D. and Madison, C. and Kivipelto, M. and Kemp, C. and McCulloch, C. E. and Galasko, D. and Artz, J. and Rentz, D. and others}, title = {{Effects of intensive lifestyle changes on the progression of mild cognitive impairment or early dementia due to Alzheimer's disease: a randomized, controlled clinical trial}}, journal = {Alzheimer's research \& therapy}, year = {2024}, doi = {10.1186/s13195-024-01482-z}, pmid = {38849944}, url = {https://doi.org/10.1186/s13195-024-01482-z} } @article{marcantonio2001-11380742, author = {Marcantonio, E. R. and Flacker, J. M. and Wright, R. J. and Resnick, N. M.}, title = {{Reducing delirium after hip fracture: a randomized trial}}, journal = {Journal of the American Geriatrics Society}, year = {2001}, doi = {10.1046/j.1532-5415.2001.49108.x}, pmid = {11380742}, url = {https://doi.org/10.1046/j.1532-5415.2001.49108.x} } @article{rojas2021-33827960, author = {Rojas, J. C. and Wang, P. and Staffaroni, A. M. and Heller, C. and Cobigo, Y. and Wolf, A. and Goh, S. M. and Ljubenkov, P. A. and others}, title = {{Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration}}, journal = {Neurology}, year = {2021}, doi = {10.1212/wnl.0000000000011848}, pmid = {33827960}, url = {https://doi.org/10.1212/wnl.0000000000011848} } @article{zhang2026-41661604, author = {Zhang, Y. and Liu, Y. and Li, Y. and Gu, X. and Kang, J. H. and others}, title = {{Coffee and Tea Intake, Dementia Risk, and Cognitive Function}}, journal = {JAMA}, year = {2026}, doi = {10.1001/jama.2025.27259}, pmid = {41661604}, url = {https://doi.org/10.1001/jama.2025.27259} } @article{leguen2023-36809323, author = {Le Guen, Y. and Raulin, A. C. and Logue, M. W. and Sherva, R. and Belloy, M. E. and Eger, S. J. and Chen, A. and Kennedy, G. and Kuchenbecker, L. and O'Leary, J. P. and Zhang, R. and Merritt, V. C. and others}, title = {{Association of African Ancestry-Specific APOE Missense Variant R145C With Risk of Alzheimer Disease}}, journal = {JAMA}, year = {2023}, doi = {10.1001/jama.2023.0268}, pmid = {36809323}, url = {https://doi.org/10.1001/jama.2023.0268} } @article{chew2015-26305649, author = {Chew, E. Y. and Clemons, T. E. and Agrón, E. and Launer, L. J. and Grodstein, F. and Bernstein, P. S.}, title = {{Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial}}, journal = {JAMA}, year = {2015}, doi = {10.1001/jama.2015.9677}, pmid = {26305649}, url = {https://doi.org/10.1001/jama.2015.9677} } @article{donohue2017-28609533, author = {Donohue, M. C. and Sperling, R. A. and Petersen, R. and Sun, C. K. and Weiner, M. W. and Aisen, P. S. and {Alzheimer’s Disease Neuroimaging Initiative}}, title = {{Association Between Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons}}, journal = {JAMA}, year = {2017}, doi = {10.1001/jama.2017.6669}, pmid = {28609533}, url = {https://doi.org/10.1001/jama.2017.6669} } @article{postuma2019-30789229, author = {Postuma, R. B. and Iranzo, A. and Hu, M. and Högl, B. and Boeve, B. F. and Manni, R. and Oertel, W. H. and Arnulf, I. and others}, title = {{Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study}}, journal = {Brain : a journal of neurology}, year = {2019}, doi = {10.1093/brain/awz030}, pmid = {30789229}, url = {https://doi.org/10.1093/brain/awz030} } @article{rhee2019-30768188, author = {Rhee, C. and Jones, T. M. and Hamad, Y. and Pande, A. and Varon, J. and O'Brien, C. and Anderson, D. J. and Warren, D. K. and others}, title = {{Prevalence, Underlying Causes, and Preventability of Sepsis-Associated Mortality in US Acute Care Hospitals}}, journal = {JAMA network open}, year = {2019}, doi = {10.1001/jamanetworkopen.2018.7571}, pmid = {30768188}, url = {https://doi.org/10.1001/jamanetworkopen.2018.7571} } @article{gomesgoncalves2023-36469335, author = {Gomes Gonçalves, N. and Vidal Ferreira, N. and Khandpur, N. and Martinez Steele, E. and Bertazzi Levy, R. and Andrade Lotufo, P. and others}, title = {{Association Between Consumption of Ultraprocessed Foods and Cognitive Decline}}, journal = {JAMA Neurology}, year = {2023}, doi = {10.1001/jamaneurol.2022.4397}, pmid = {36469335}, url = {https://doi.org/10.1001/jamaneurol.2022.4397} } @article{quiroz2024-38899694, author = {Quiroz, Y. T. and Aguillon, D. and Aguirre-Acevedo, D. C. and Vasquez, D. and Zuluaga, Y. and Baena, A. Y. and Madrigal, L. and Hincapié, L. and Sanchez, J. S. and Langella, S. and Posada-Duque, R. and Littau, J. L. and others}, title = {{APOE3 Christchurch Heterozygosity and Autosomal Dominant Alzheimer's Disease}}, journal = {New England Journal of Medicine}, year = {2024}, doi = {10.1056/NEJMoa2308583}, pmid = {38899694}, url = {https://doi.org/10.1056/NEJMoa2308583} } @article{cronje2023-37392405, author = {Cronjé, H. T. and Liu, X. and Odden, M. C. and Moseholm, K. F. and Seshadri, S. and Satizabal, C. L. and Lopez, O. L. and Bis, J. C. and Djoussé, L. and Fohner, A. E. and Psaty, B. M. and Tracy, R. P. and others}, title = {{Serum NfL and GFAP are associated with incident dementia and dementia mortality in older adults: The cardiovascular health study}}, journal = {Alzheimer's \& Dementia}, year = {2023}, doi = {10.1002/alz.13367}, pmid = {37392405}, url = {https://doi.org/10.1002/alz.13367} } @article{naj2014-25199842, author = {Naj, A. C. and Jun, G. and Reitz, C. and Kunkle, B. W. and Perry, W. and Park, Y. S. and Beecham, G. W. and Rajbhandary, R. A. and others}, title = {{Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study}}, journal = {JAMA neurology}, year = {2014}, doi = {10.1001/jamaneurol.2014.1491}, pmid = {25199842}, url = {https://doi.org/10.1001/jamaneurol.2014.1491} } @article{volandes2023-37695586, author = {Volandes, A. E. and Zupanc, S. N. and Lakin, JR. and Cabral, H. J. and Burns, E. A. and Carney, M. T. and Lopez, S. and Itty, J. and others}, title = {{Video Intervention and Goals-of-Care Documentation in Hospitalized Older Adults: The VIDEO-PCE Randomized Clinical Trial}}, journal = {JAMA network open}, year = {2023}, doi = {10.1001/jamanetworkopen.2023.32556}, pmid = {37695586}, url = {https://doi.org/10.1001/jamanetworkopen.2023.32556} } @article{gustavsson2011-21924589, author = {Gustavsson, A. and Svensson, M. and Jacobi, F. and Allgulander, C. and Alonso, J. and Beghi, E. and Dodel, R. and Ekman, M. and others}, title = {{Cost of disorders of the brain in Europe 2010}}, journal = {European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology}, year = {2011}, doi = {10.1016/j.euroneuro.2011.08.008}, pmid = {21924589}, url = {https://doi.org/10.1016/j.euroneuro.2011.08.008} } @article{dias2019-30422259, author = {Dias, A. and Azariah, F. and Anderson, S. J. and Sequeira, M. and Cohen, A. and Morse, J. Q. and Cuijpers, P. and Patel, V. and others}, title = {{Effect of a Lay Counselor Intervention on Prevention of Major Depression in Older Adults Living in Low- and Middle-Income Countries: A Randomized Clinical Trial}}, journal = {JAMA psychiatry}, year = {2019}, doi = {10.1001/jamapsychiatry.2018.3048}, pmid = {30422259}, url = {https://doi.org/10.1001/jamapsychiatry.2018.3048} } @article{wang2005-16319382, author = {Wang, P. S. and Schneeweiss, S. and Avorn, J. and Fischer, M. A. and Mogun, H. and Solomon, D. H. and Brookhart, M. A.}, title = {{Risk of death in elderly users of conventional vs. atypical antipsychotic medications}}, journal = {The New England journal of medicine}, year = {2005}, doi = {10.1056/nejmoa052827}, pmid = {16319382}, url = {https://doi.org/10.1056/nejmoa052827} } @article{gill2007-17548409, author = {Gill, S. S. and Bronskill, S. E. and Normand, S. L. and Anderson, G. M. and Sykora, K. and Lam, K. and Bell, C. M. and Lee, P. E. and others}, title = {{Antipsychotic drug use and mortality in older adults with dementia}}, journal = {Annals of internal medicine}, year = {2007}, doi = {10.7326/0003-4819-146-11-200706050-00006}, pmid = {17548409}, url = {https://doi.org/10.7326/0003-4819-146-11-200706050-00006} } @article{hampel2020-32296418, author = {Hampel, H. and Caraci, F. and Cuello, A. C. and Caruso, G. and Nisticò, R. and Corbo, M. and Baldacci, F. and Toschi, N. and others}, title = {{A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer's Disease}}, journal = {Frontiers in immunology}, year = {2020}, doi = {10.3389/fimmu.2020.00456}, pmid = {32296418}, url = {https://doi.org/10.3389/fimmu.2020.00456} } @article{wang2023-36848126, author = {Wang, X. and Ma, H. and Li, X. and Heianza, Y. and Manson, J. E. and Franco, O. H. and Qi, L.}, title = {{Association of Cardiovascular Health With Life Expectancy Free of Cardiovascular Disease, Diabetes, Cancer, and Dementia in UK Adults}}, journal = {JAMA internal medicine}, year = {2023}, doi = {10.1001/jamainternmed.2023.0015}, pmid = {36848126}, url = {https://doi.org/10.1001/jamainternmed.2023.0015} } @article{nelson2014-24770881, author = {Nelson, P. T. and Estus, S. and Abner, E. L. and Parikh, I. and Malik, M. and Neltner, J. H. and Ighodaro, E. and Wang, W. X. and others}, title = {{ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology}}, journal = {Acta neuropathologica}, year = {2014}, doi = {10.1007/s00401-014-1282-2}, pmid = {24770881}, url = {https://doi.org/10.1007/s00401-014-1282-2} } @article{sun2026-41854616, author = {Sun, Haoqi and Milton, Sasha and Fang, Yi and Taha, Hash Brown and Shiju, Shreya and Thomas, Robert J and Ganglberger, Wolfgang and Pase, Matthew P and others}, title = {{Machine Learning-Based Sleep Electroencephalographic Brain Age Index and Dementia Risk: An Individual Participant Data Meta-Analysis}}, journal = {JAMA network open}, year = {2026}, doi = {10.1001/jamanetworkopen.2026.1521}, pmid = {41854616}, url = {https://doi.org/10.1001/jamanetworkopen.2026.1521} } @article{hohman2018-29801024, author = {Hohman, T. J. and Dumitrescu, L. and Barnes, L. L. and Thambisetty, M. and Beecham, G. and Kunkle, B. and Gifford, K. A. and Bush, W. S. and others}, title = {{Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau}}, journal = {JAMA neurology}, year = {2018}, doi = {10.1001/jamaneurol.2018.0821}, pmid = {29801024}, url = {https://doi.org/10.1001/jamaneurol.2018.0821} } @article{singh2024-39432286, author = {Singh, S. and Li, X. and Cocoros, N. M. and Antonelli, M. T. and Avula, R. and Crawford, S. L. and Dashevsky, I. and Fouayzi, H. and others}, title = {{High-Risk Medications in Persons Living With Dementia: A Randomized Clinical Trial}}, journal = {JAMA internal medicine}, year = {2024}, doi = {10.1001/jamainternmed.2024.5632}, pmid = {39432286}, url = {https://doi.org/10.1001/jamainternmed.2024.5632} } @article{fong2009-19414723, author = {Fong, T. G. and Jones, R. N. and Shi, P. and Marcantonio, E. R. and Yap, L. and Rudolph, J. L. and Yang, F. M. and Kiely, D. K. and others}, title = {{Delirium accelerates cognitive decline in Alzheimer disease}}, journal = {Neurology}, year = {2009}, doi = {10.1212/wnl.0b013e3181a4129a}, pmid = {19414723}, url = {https://doi.org/10.1212/wnl.0b013e3181a4129a} } @article{mukamal2003-12636463, author = {Mukamal, K. J. and Kuller, L. H. and Fitzpatrick, A. L. and Longstreth, W. T. and Mittleman, M. A. and Siscovick, D. S.}, title = {{Prospective study of alcohol consumption and risk of dementia in older adults}}, journal = {JAMA}, year = {2003}, doi = {10.1001/jama.289.11.1405}, pmid = {12636463}, url = {https://doi.org/10.1001/jama.289.11.1405} } @article{borchert2023-37563912, author = {Borchert, R. J. and Azevedo, T. and Badhwar, A. and Bernal, J. and Betts, M. and Bruffaerts, R. and Burkhart, M. C. and Dewachter, I. and others}, title = {{Artificial intelligence for diagnostic and prognostic neuroimaging in dementia: A systematic review}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2023}, doi = {10.1002/alz.13412}, pmid = {37563912}, url = {https://doi.org/10.1002/alz.13412} } @article{yaffe2011-21828324, author = {Yaffe, K. and Laffan, A. M. and Harrison, S. L. and Redline, S. and Spira, A. P. and Ensrud, K. E. and Ancoli-Israel, S. and Stone, K. L.}, title = {{Sleep-disordered breathing, hypoxia, and risk of mild cognitive impairment and dementia in older women}}, journal = {JAMA}, year = {2011}, doi = {10.1001/jama.2011.1115}, pmid = {21828324}, url = {https://doi.org/10.1001/jama.2011.1115} } @article{parhizkar2019-30617257, author = {Parhizkar, S. and Arzberger, T. and Brendel, M. and Kleinberger, G. and Deussing, M. and Focke, C. and Nuscher, B. and Xiong, M. and others}, title = {{Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE}}, journal = {Nature neuroscience}, year = {2019}, doi = {10.1038/s41593-018-0296-9}, pmid = {30617257}, url = {https://doi.org/10.1038/s41593-018-0296-9} } @article{roostaei2017-27021820, author = {Roostaei, T. and Nazeri, A. and Felsky, D. and De Jager, P. L. and Schneider, J. A. and Pollock, B. G. and Bennett, D. A. and Voineskos, A. N. and others}, title = {{Genome-wide interaction study of brain beta-amyloid burden and cognitive impairment in Alzheimer's disease}}, journal = {Molecular psychiatry}, year = {2017}, doi = {10.1038/mp.2016.35}, pmid = {27021820}, url = {https://doi.org/10.1038/mp.2016.35} } @article{tessier2024-38709531, author = {Tessier, A. J. and Cortese, M. and Yuan, C. and Bjornevik, K. and Ascherio, A. and Wang, D. D. and Chavarro, J. E. and Stampfer, M. J. and Hu, F. B. and Willett, W. C. and others}, title = {{Consumption of Olive Oil and Diet Quality and Risk of Dementia-Related Death}}, journal = {JAMA Network Open}, year = {2024}, doi = {10.1001/jamanetworkopen.2024.10021}, pmid = {38709531}, url = {https://doi.org/10.1001/jamanetworkopen.2024.10021} } @article{atri2024-39713942, author = {Atri, A. and Dickerson, B. C. and Clevenger, C. and Karlawish, J. and Knopman, D. and Lin, P. J. and Norman, M. and Onyike, C. and Sano, M. and Scanland, S. and others}, title = {{Alzheimer's Association clinical practice guideline for the Diagnostic Evaluation, Testing, Counseling, and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD-ADRD): Executive summary of recommendations for primary care}}, journal = {Alzheimer's \& Dementia}, year = {2024}, doi = {10.1002/alz.14333}, pmid = {39713942}, url = {https://doi.org/10.1002/alz.14333} } @article{sanchez2025-40063856, author = {Sanchez, E. and Coughlan, G. T. and Wilkinson, T. and Ramirez, J. and Mirza, S. S. and Baril, A. A. and Dilliott, A. A. and Frank, A. and others}, title = {{Association of Plasma Biomarkers With Longitudinal Atrophy and Microvascular Burden on MRI Across Neurodegenerative and Cerebrovascular Diseases}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000213438}, pmid = {40063856}, url = {https://doi.org/10.1212/wnl.0000000000213438} } @article{sargurupremraj2020-33293549, author = {Sargurupremraj, M. and Suzuki, H. and Jian, X. and Sarnowski, C. and Evans, T. E. and Bis, J. C. and Eiriksdottir, G. and Sakaue, S. and others}, title = {{Cerebral small vessel disease genomics and its implications across the lifespan}}, journal = {Nature communications}, year = {2020}, doi = {10.1038/s41467-020-19111-2}, pmid = {33293549}, url = {https://doi.org/10.1038/s41467-020-19111-2} } @article{shinto2024-39088212, author = {Shinto, L. H. and Murchison, C. F. and Silbert, L. C. and Dodge, H. H. and Lahna, D. and Rooney, W. and Kaye, J. and Quinn, J. F. and others}, title = {{ω-3 PUFA for Secondary Prevention of White Matter Lesions and Neuronal Integrity Breakdown in Older Adults: A Randomized Clinical Trial}}, journal = {JAMA network open}, year = {2024}, doi = {10.1001/jamanetworkopen.2024.26872}, pmid = {39088212}, url = {https://doi.org/10.1001/jamanetworkopen.2024.26872} } @article{wayne2014-24383523, author = {Wayne, P. M. and Walsh, J. N. and Taylor-Piliae, R. E. and Wells, R. E. and Papp, K. V. and Donovan, N. J. and Yeh, G. Y.}, title = {{Effect of tai chi on cognitive performance in older adults: systematic review and meta-analysis}}, journal = {Journal of the American Geriatrics Society}, year = {2014}, doi = {10.1111/jgs.12611}, pmid = {24383523}, url = {https://doi.org/10.1111/jgs.12611} } @article{sperling2011-21514248, author = {Sperling, R. A. and Aisen, P. S. and Beckett, L. A. and Bennett, D. A. and Craft, S. and Fagan, A. M. and Iwatsubo, T. and Jack, C. R. and others}, title = {{Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2011}, doi = {10.1016/j.jalz.2011.03.003}, pmid = {21514248}, url = {https://doi.org/10.1016/j.jalz.2011.03.003} } @article{dube2019-31591557, author = {Dube, U. and Del-Aguila, J. L. and Li, Z. and Budde, J. P. and Jiang, S. and Hsu, S. and Ibanez, L. and Fernandez, M. V. and others}, title = {{An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations}}, journal = {Nature neuroscience}, year = {2019}, doi = {10.1038/s41593-019-0501-5}, pmid = {31591557}, url = {https://doi.org/10.1038/s41593-019-0501-5} } @article{moguilner2024-39187698, author = {Moguilner, S. and Baez, S. and Hernandez, H. and Migeot, J. and Legaz, A. and Gonzalez-Gomez, R. and Farina, F. R. and Prado, P. and others}, title = {{Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations}}, journal = {Nature medicine}, year = {2024}, doi = {10.1038/s41591-024-03209-x}, pmid = {39187698}, url = {https://doi.org/10.1038/s41591-024-03209-x} } @article{marden2014-25328845, author = {Marden, JR. and Walter, S. and Tchetgen Tchetgen, E. J. and Kawachi, I. and Glymour, M. M.}, title = {{Validation of a polygenic risk score for dementia in black and white individuals}}, journal = {Brain and behavior}, year = {2014}, doi = {10.1002/brb3.248}, pmid = {25328845}, url = {https://doi.org/10.1002/brb3.248} } @article{driver2012-22411920, author = {Driver, J. A. and Beiser, A. and Au, R. and Kreger, B. E. and Splansky, G. L. and Kurth, T. and Kiel, D. P. and Lu, K. P. and others}, title = {{Inverse association between cancer and Alzheimer's disease: results from the Framingham Heart Study}}, journal = {BMJ (Clinical research ed.)}, year = {2012}, doi = {10.1136/bmj.e1442}, pmid = {22411920}, url = {https://doi.org/10.1136/bmj.e1442} } @article{younan2020-31746986, author = {Younan, D. and Petkus, A. J. and Widaman, K. F. and Wang, X. and Casanova, R. and Espeland, M. A. and Gatz, M. and Henderson, V. W. and others}, title = {{Particulate matter and episodic memory decline mediated by early neuroanatomic biomarkers of Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2020}, doi = {10.1093/brain/awz348}, pmid = {31746986}, url = {https://doi.org/10.1093/brain/awz348} } @article{szwedo2022-35106798, author = {Szwedo, A. A. and Dalen, I. and Pedersen, K. F. and Camacho, M. and Bäckström, D. and Forsgren, L. and Tzoulis, C. and Winder-Rhodes, S. and others}, title = {{GBA and APOE Impact Cognitive Decline in Parkinson's Disease: A 10-Year Population-Based Study}}, journal = {Movement disorders : official journal of the Movement Disorder Society}, year = {2022}, doi = {10.1002/mds.28932}, pmid = {35106798}, url = {https://doi.org/10.1002/mds.28932} } @article{vanderlee2018-29555425, author = {van der Lee, S. J. and Wolters, F. J. and Ikram, M. K. and Hofman, A. and Ikram, M. A. and Amin, N. and van Duijn, C. M.}, title = {{The effect of APOE and other common genetic variants on the onset of Alzheimer's disease and dementia: a community-based cohort study}}, journal = {The Lancet. Neurology}, year = {2018}, doi = {10.1016/s1474-4422(18)30053-x}, pmid = {29555425}, url = {https://doi.org/10.1016/s1474-4422(18)30053-x} } @article{kwok2025-40094667, author = {Kwok, J. Y. Y. and Cheung, D. S. K. and Zarit, S. and Cheung, K. S. and Lau, B. H. P. and Lou, V. W. and Cheng, S. T. and Gallagher-Thompson, D. and Qian, M. and Chou, K. L.}, title = {{Multicomponent Intervention for Distressed Informal Caregivers of People With Dementia: A Randomized Clinical Trial}}, journal = {JAMA Network Open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.0069}, pmid = {40094667}, url = {https://doi.org/10.1001/jamanetworkopen.2025.0069} } @article{shadyab2026-41805953, author = {Shadyab, A. H. and Zhang, B. and LaCroix, A. Z. and Mielke, M. M. and Resnick, S. M. and Nguyen, S. and Ferrucci, L. and Libermann, T. A. and Ngo, L. and Casanova, R. and others}, title = {{Plasma Phosphorylated Tau 217 and Incident Mild Cognitive Impairment and Dementia in Older Women}}, journal = {JAMA Network Open}, year = {2026}, doi = {10.1001/jamanetworkopen.2026.1295}, pmid = {41805953}, url = {https://doi.org/10.1001/jamanetworkopen.2026.1295} } @article{wilker2023-37019461, author = {Wilker, E. H. and Osman, M. and Weisskopf, M. G.}, title = {{Ambient air pollution and clinical dementia: systematic review and meta-analysis}}, journal = {BMJ}, year = {2023}, doi = {10.1136/bmj-2022-071620}, pmid = {37019461}, url = {https://doi.org/10.1136/bmj-2022-071620} } @article{insel2025-40853684, author = {Insel, P. S. and Mattsson-Carlgren, N. and Langford, O. and Caruso, V. M. and Leuzy, A. and Young, C. B. and Boxer, A. and Aisen, P. S. and Sperling, R. A. and Mormino, E. C. and Donohue, M. C.}, title = {{Concurrent Changes in Plasma Phosphorylated Tau 217, Tau PET, and Cognition in Preclinical Alzheimer Disease}}, journal = {JAMA Neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.2974}, pmid = {40853684}, url = {https://doi.org/10.1001/jamaneurol.2025.2974} } @article{verhaaren2015-25663218, author = {Verhaaren, B. F. and Debette, S. and Bis, J. C. and Smith, J. A. and Ikram, M. K. and Adams, H. H. and Beecham, A. H. and Rajan, K. B. and others}, title = {{Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI}}, journal = {Circulation. Cardiovascular genetics}, year = {2015}, doi = {10.1161/circgenetics.114.000858}, pmid = {25663218}, url = {https://doi.org/10.1161/circgenetics.114.000858} } @article{grodstein2013-24490265, author = {Grodstein, F. and O'Brien, J. and Kang, J. H. and Dushkes, R. and Cook, N. R. and Okereke, O. and Manson, J. E. and Glynn, R. J. and others}, title = {{Long-term multivitamin supplementation and cognitive function in men: a randomized trial}}, journal = {Annals of internal medicine}, year = {2013}, doi = {10.7326/0003-4819-159-12-201312170-00006}, pmid = {24490265}, url = {https://doi.org/10.7326/0003-4819-159-12-201312170-00006} } @article{christensen2018-28726810, author = {Christensen, K. D. and Uhlmann, W. R. and Roberts, J. S. and Linnenbringer, E. and Whitehouse, P. J. and Royal, C. D. M. and Obisesan, T. O. and Cupples, L. A. and others}, title = {{A randomized controlled trial of disclosing genetic risk information for Alzheimer disease via telephone}}, journal = {Genetics in medicine : official journal of the American College of Medical Genetics}, year = {2018}, doi = {10.1038/gim.2017.103}, pmid = {28726810}, url = {https://doi.org/10.1038/gim.2017.103} } @article{rabin2018-29799986, author = {Rabin, J. S. and Schultz, A. P. and Hedden, T. and Viswanathan, A. and Marshall, G. A. and Kilpatrick, E. and Klein, H. and Buckley, R. F. and others}, title = {{Interactive Associations of Vascular Risk and β-Amyloid Burden With Cognitive Decline in Clinically Normal Elderly Individuals: Findings From the Harvard Aging Brain Study}}, journal = {JAMA neurology}, year = {2018}, doi = {10.1001/jamaneurol.2018.1123}, pmid = {29799986}, url = {https://doi.org/10.1001/jamaneurol.2018.1123} } @article{sanchez2021-33472953, author = {Sanchez, J. S. and Becker, J. A. and Jacobs, H. I. L. and Hanseeuw, B. J. and Jiang, S. and Schultz, A. P. and Properzi, M. J. and Katz, SR. and others}, title = {{The cortical origin and initial spread of medial temporal tauopathy in Alzheimer's disease assessed with positron emission tomography}}, journal = {Science translational medicine}, year = {2021}, doi = {10.1126/scitranslmed.abc0655}, pmid = {33472953}, url = {https://doi.org/10.1126/scitranslmed.abc0655} } @article{fortea2024-38710950, author = {Fortea, J. and Pegueroles, J. and Alcolea, D. and Belbin, O. and Dols-Icardo, O. and Vaqué-Alcázar, L. and Videla, L. and Gispert, J. D. and others}, title = {{APOE4 homozygozity represents a distinct genetic form of Alzheimer's disease}}, journal = {Nature medicine}, year = {2024}, doi = {10.1038/s41591-024-02931-w}, pmid = {38710950}, url = {https://doi.org/10.1038/s41591-024-02931-w} } @article{costoyasanchez2023-37578787, author = {Costoya-Sánchez, A. and Moscoso, A. and Silva-Rodríguez, J. and Pontecorvo, M. J. and Devous, M. D. and Aguiar, P. and Schöll, M. and Grothe, M. J. and others}, title = {{Increased Medial Temporal Tau Positron Emission Tomography Uptake in the Absence of Amyloid-β Positivity}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.2560}, pmid = {37578787}, url = {https://doi.org/10.1001/jamaneurol.2023.2560} } @article{weiner2015-26073027, author = {Weiner, M. W. and Veitch, D. P. and Aisen, P. S. and Beckett, L. A. and Cairns, N. J. and Cedarbaum, J. and Green, R. C. and Harvey, D. and others}, title = {{2014 Update of the Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2015}, doi = {10.1016/j.jalz.2014.11.001}, pmid = {26073027}, url = {https://doi.org/10.1016/j.jalz.2014.11.001} } @article{mathys2024-39048816, author = {Mathys, H. and Boix, C. A. and Akay, L. A. and Xia, Z. and Davila-Velderrain, J. and Ng, A. P. and Jiang, X. and Abdelhady, G. and others}, title = {{Single-cell multiregion dissection of Alzheimer's disease}}, journal = {Nature}, year = {2024}, doi = {10.1038/s41586-024-07606-7}, pmid = {39048816}, url = {https://doi.org/10.1038/s41586-024-07606-7} } @article{ko2022-36399339, author = {Ko, Darae and Lin, Kueiyu Joshua and Bessette, Lily Gui and Lee, Su Been and Walkey, Allan J. and Cheng, Susan C. and Kim, Erin and Glynn, Robert J. and others}, title = {{Trends in Use of Oral Anticoagulants in Older Adults With Newly Diagnosed Atrial Fibrillation, 2010-2020}}, journal = {JAMA Network Open}, year = {2022}, doi = {10.1001/jamanetworkopen.2022.42964}, pmid = {36399339}, url = {https://doi.org/10.1001/jamanetworkopen.2022.42964} } @article{topiwala2026-40987604, author = {Topiwala, A. and Levey, D. F. and Zhou, H. and Deak, J. D. and Adhikari, K. and Ebmeier, K. P. and others}, title = {{Alcohol use and risk of dementia in diverse populations: evidence from cohort, case-control and Mendelian randomisation approaches}}, journal = {BMJ Evidence-Based Medicine}, year = {2026}, doi = {10.1136/bmjebm-2025-113913}, pmid = {40987604}, url = {https://doi.org/10.1136/bmjebm-2025-113913} } @article{coughlan2026-41697669, author = {Coughlan, Gillian T and Ourry, Valentin and Townsend, Diana and Klinger, Hannah and Brown, Jane A and Cuppels, Madison and Betthauser, Tobey and Langhough, Rebecca and others}, title = {{Sex Differences in P-Tau217, Tau Aggregation, and Cognitive Decline}}, journal = {JAMA neurology}, year = {2026}, doi = {10.1001/jamaneurol.2025.5670}, pmid = {41697669}, url = {https://doi.org/10.1001/jamaneurol.2025.5670} } @article{sperling2020-32250387, author = {Sperling, R. A. and Donohue, M. C. and Raman, R. and Sun, C. K. and Yaari, R. and Holdridge, K. and Siemers, E. and Johnson, K. A. and others}, title = {{Association of Factors With Elevated Amyloid Burden in Clinically Normal Older Individuals}}, journal = {JAMA neurology}, year = {2020}, doi = {10.1001/jamaneurol.2020.0387}, pmid = {32250387}, url = {https://doi.org/10.1001/jamaneurol.2020.0387} } @article{liu2018-29429971, author = {Liu, E. and Wang, D. and Sperling, R. and Salloway, S. and Fox, N. C. and Blennow, K. and Scheltens, P. and Schmidt, M. E. and others}, title = {{Biomarker pattern of ARIA-E participants in phase 3 randomized clinical trials with bapineuzumab}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000005060}, pmid = {29429971}, url = {https://doi.org/10.1212/wnl.0000000000005060} } @article{yang2024-38315899, author = {Yang, H. S. and Yau, W. W. and Carlyle, B. C. and Trombetta, B. A. and Zhang, C. and Shirzadi, Z. and Schultz, A. P. and Pruzin, J. J. and others}, title = {{Plasma VEGFA and PGF impact longitudinal tau and cognition in preclinical Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2024}, doi = {10.1093/brain/awae034}, pmid = {38315899}, url = {https://doi.org/10.1093/brain/awae034} } @article{yu2015-25365775, author = {Yu, L. and Chibnik, L. B. and Srivastava, G. P. and Pochet, N. and Yang, J. and Xu, J. and Kozubek, J. and Obholzer, N. and others}, title = {{Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease}}, journal = {JAMA neurology}, year = {2015}, doi = {10.1001/jamaneurol.2014.3049}, pmid = {25365775}, url = {https://doi.org/10.1001/jamaneurol.2014.3049} } @article{shao2012-23100399, author = {Shao, H. and Breitner, J. C. and Whitmer, R. A. and Wang, J. and Hayden, K. and Wengreen, H. and Corcoran, C. and Tschanz, J. and others}, title = {{Hormone therapy and Alzheimer disease dementia: new findings from the Cache County Study}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e318271f823}, pmid = {23100399}, url = {https://doi.org/10.1212/wnl.0b013e318271f823} } @article{dubbelman2025-40440591, author = {Dubbelman, M. A. and Liu, A. and Donohue, M. C. and Langford, O. and Raman, R. and Rentz, D. M. and Amariglio, R. and Sperling, R. A. and others}, title = {{Changes in Daily Functioning in Association With Tau and Amyloid Among Unimpaired Older Adults With and Without Elevated Amyloid}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000213775}, pmid = {40440591}, url = {https://doi.org/10.1212/wnl.0000000000213775} } @article{chen2016-26086180, author = {Chen, J. C. and Espeland, M. A. and Brunner, R. L. and Lovato, L. C. and Wallace, R. B. and Leng, X. and Phillips, L. S. and Robinson, J. G. and others}, title = {{Sleep duration, cognitive decline, and dementia risk in older women}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2016}, doi = {10.1016/j.jalz.2015.03.004}, pmid = {26086180}, url = {https://doi.org/10.1016/j.jalz.2015.03.004} } @article{jick2000-11089820, author = {Jick, H. and Zornberg, G. L. and Jick, S. S. and Seshadri, S. and Drachman, D. A.}, title = {{Statins and the risk of dementia}}, journal = {Lancet (London, England)}, year = {2000}, doi = {10.1016/s0140-6736(00)03155-x}, pmid = {11089820}, url = {https://doi.org/10.1016/s0140-6736(00)03155-x} } @article{dewolf2020-32206776, author = {de Wolf, F. and Ghanbari, M. and Licher, S. and McRae-McKee, K. and Gras, L. and Weverling, G. J. and Wermeling, P. and Sedaghat, S. and others}, title = {{Plasma tau, neurofilament light chain and amyloid-β levels and risk of dementia; a population-based cohort study}}, journal = {Brain : a journal of neurology}, year = {2020}, doi = {10.1093/brain/awaa054}, pmid = {32206776}, url = {https://doi.org/10.1093/brain/awaa054} } @article{gleason2015-26352694, author = {Gleason, L. J. and Schmitt, E. M. and Kosar, C. M. and Tabloski, P. and Saczynski, J. S. and Robinson, T. and Cooper, Z. and Rogers, S. O. and others}, title = {{Effect of Delirium and Other Major Complications on Outcomes After Elective Surgery in Older Adults}}, journal = {JAMA surgery}, year = {2015}, doi = {10.1001/jamasurg.2015.2606}, pmid = {26352694}, url = {https://doi.org/10.1001/jamasurg.2015.2606} } @article{husebo2019-32116687, author = {Husebo, B. S. and Heintz, H. L. and Berge, L. I. and Owoyemi, P. and Rahman, A. T. and Vahia, IV.}, title = {{Sensing Technology to Monitor Behavioral and Psychological Symptoms and to Assess Treatment Response in People With Dementia. A Systematic Review}}, journal = {Frontiers in pharmacology}, year = {2019}, doi = {10.3389/fphar.2019.01699}, pmid = {32116687}, url = {https://doi.org/10.3389/fphar.2019.01699} } @article{ayton2015-25988319, author = {Ayton, S. and Faux, N. G. and Bush, A. I. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE}}, journal = {Nature communications}, year = {2015}, doi = {10.1038/ncomms7760}, pmid = {25988319}, url = {https://doi.org/10.1038/ncomms7760} } @article{carrasquillo2017-27939925, author = {Carrasquillo, M. M. and Allen, M. and Burgess, J. D. and Wang, X. and Strickland, S. L. and Aryal, S. and Siuda, J. and Kachadoorian, M. L. and others}, title = {{A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2017}, doi = {10.1016/j.jalz.2016.10.005}, pmid = {27939925}, url = {https://doi.org/10.1016/j.jalz.2016.10.005} } @article{miyagawa2020-31914218, author = {Miyagawa, T. and Brushaber, D. and Syrjanen, J. and Kremers, W. and Fields, J. and Forsberg, L. K. and Heuer, H. W. and Knopman, D. and others}, title = {{Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2020}, doi = {10.1002/alz.12033}, pmid = {31914218}, url = {https://doi.org/10.1002/alz.12033} } @article{rojassaunero2023-37139580, author = {Rojas-Saunero, L. P. and Young, J. G. and Didelez, V. and Ikram, M. A. and Swanson, S. A.}, title = {{Considering Questions Before Methods in Dementia Research With Competing Events and Causal Goals}}, journal = {American journal of epidemiology}, year = {2023}, doi = {10.1093/aje/kwad090}, pmid = {37139580}, url = {https://doi.org/10.1093/aje/kwad090} } @article{dumanski2016-27231129, author = {Dumanski, J. P. and Lambert, J. C. and Rasi, C. and Giedraitis, V. and Davies, H. and Grenier-Boley, B. and Lindgren, C. M. and Campion, D. and others}, title = {{Mosaic Loss of Chromosome Y in Blood Is Associated with Alzheimer Disease}}, journal = {American journal of human genetics}, year = {2016}, doi = {10.1016/j.ajhg.2016.05.014}, pmid = {27231129}, url = {https://doi.org/10.1016/j.ajhg.2016.05.014} } @article{yeo2025-40111358, author = {Yeo, Brian Sheng Yep and Tan, Vanessa Yee Jueen and Ng, Jia Hui and Tang, Joyce Zhi’en and Sim, Brenda Ling Hui and Tay, Yu Ling and Chowdhury, Anupama Roy and David, Abel P. and others}, title = {{Hearing Loss and Falls}}, journal = {JAMA Otolaryngology–Head \& Neck Surgery}, year = {2025}, doi = {10.1001/jamaoto.2025.0056}, pmid = {40111358}, url = {https://doi.org/10.1001/jamaoto.2025.0056} } @article{himali2023-37902739, author = {Himali, J. J. and Baril, A. A. and Cavuoto, M. G. and Yiallourou, S. and Wiedner, C. D. and Himali, D. and others}, title = {{Association Between Slow-Wave Sleep Loss and Incident Dementia}}, journal = {JAMA Neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.3889}, pmid = {37902739}, url = {https://doi.org/10.1001/jamaneurol.2023.3889} } @article{buckley2026-42449500, author = {Buckley, Rachel F and Townsend, Diana L and Birkenbihl, Colin J and Cuppels, Madison and Coughlan, Gillian T and Seto, Mabel T and Brown, Jane A and Properzi, Michael J and others}, title = {{Prognostic Value of Blood-Based P-Tau217 Levels for Progression to Cognitive Impairment}}, journal = {JAMA}, year = {2026}, doi = {10.1001/jama.2026.12556}, pmid = {42449500}, url = {https://doi.org/10.1001/jama.2026.12556} } @article{sipila2026-41969011, author = {Sipilä, Pyry N and Pentti, Jaana and Frank, Philipp and Duggan, Michael R and Walker, Keenan A and Strandberg, Timo E and Lindbohm, Joni V and Kivimäki, Mika}, title = {{The role of frailty and comorbidities in severe infections and the risk of dementia: a prospective, multicohort, observational study}}, journal = {The lancet. Healthy longevity}, year = {2026}, doi = {10.1016/j.lanhl.2026.100826}, pmid = {41969011}, url = {https://doi.org/10.1016/j.lanhl.2026.100826} } @article{nguyenho2024-38913396, author = {Nguyen Ho, P. T. and Hoepel, S. J. W. and Rodriguez-Ayllon, M. and Luik, A. I. and Vernooij, M. W. and Neitzel, J.}, title = {{Sleep, 24-Hour Activity Rhythms, and Subsequent Amyloid-β Pathology}}, journal = {JAMA neurology}, year = {2024}, doi = {10.1001/jamaneurol.2024.1755}, pmid = {38913396}, url = {https://doi.org/10.1001/jamaneurol.2024.1755} } @article{wisch2024-38631766, author = {Wisch, J. K. and McKay, N. S. and Boerwinkle, A. H. and Kennedy, J. and Flores, S. and Handen, B. L. and Christian, B. T. and Head, E. and others}, title = {{Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study}}, journal = {The Lancet. Neurology}, year = {2024}, doi = {10.1016/s1474-4422(24)00084-x}, pmid = {38631766}, url = {https://doi.org/10.1016/s1474-4422(24)00084-x} } @article{wetmore2024-39748836, author = {Wetmore, J. B. and Rodriguez, S. and Diaz Caro, D. and Cabán, M. and Uhlmann, W. and Goldman, J. and Leu, C. S. and Godinez, J. D. and others}, title = {{Designing and implementing the IDEAL Study: A randomized clinical trial of APOE genotype disclosure for late-onset Alzheimer's disease in an urban Latino population}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2024}, doi = {10.1002/trc2.70016}, pmid = {39748836}, url = {https://doi.org/10.1002/trc2.70016} } @article{nelson2019-31039256, author = {Nelson, P. T. and Dickson, D. W. and Trojanowski, J. Q. and Jack, C. R. and Boyle, P. A. and Arfanakis, K. and Rademakers, R. and Alafuzoff, I. and others}, title = {{Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report}}, journal = {Brain : a journal of neurology}, year = {2019}, doi = {10.1093/brain/awz099}, pmid = {31039256}, url = {https://doi.org/10.1093/brain/awz099} } @article{crane2013-23924004, author = {Crane, P. K. and Walker, R. and Hubbard, R. A. and Li, G. and Nathan, D. M. and Zheng, H. and Haneuse, S. and Craft, S. and others}, title = {{Glucose levels and risk of dementia}}, journal = {The New England journal of medicine}, year = {2013}, doi = {10.1056/nejmoa1215740}, pmid = {23924004}, url = {https://doi.org/10.1056/nejmoa1215740} } @article{bakkour2009-19109536, author = {Bakkour, A. and Morris, J. C. and Dickerson, B. C.}, title = {{The cortical signature of prodromal AD: regional thinning predicts mild AD dementia}}, journal = {Neurology}, year = {2009}, doi = {10.1212/01.wnl.0000340981.97664.2f}, pmid = {19109536}, url = {https://doi.org/10.1212/01.wnl.0000340981.97664.2f} } @article{shirzadi2023-37843849, author = {Shirzadi, Z. and Schultz, S. A. and Yau, W. W. and Joseph-Mathurin, N. and Fitzpatrick, C. D. and Levin, R. and Kantarci, K. and Preboske, G. M. and others}, title = {{Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.3618}, pmid = {37843849}, url = {https://doi.org/10.1001/jamaneurol.2023.3618} } @article{langa2008-18631957, author = {Langa, K. M. and Larson, E. B. and Karlawish, J. H. and Cutler, D. M. and Kabeto, M. U. and Kim, S. Y. and Rosen, A. B.}, title = {{Trends in the prevalence and mortality of cognitive impairment in the United States: is there evidence of a compression of cognitive morbidity?}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2008}, doi = {10.1016/j.jalz.2008.01.001}, pmid = {18631957}, url = {https://doi.org/10.1016/j.jalz.2008.01.001} } @article{henschel2020-32526386, author = {Henschel, L. and Conjeti, S. and Estrada, S. and Diers, K. and Fischl, B. and Reuter, M.}, title = {{FastSurfer - A fast and accurate deep learning based neuroimaging pipeline}}, journal = {NeuroImage}, year = {2020}, doi = {10.1016/j.neuroimage.2020.117012}, pmid = {32526386}, url = {https://doi.org/10.1016/j.neuroimage.2020.117012} } @article{young2018-30323170, author = {Young, A. L. and Marinescu, R. V. and Oxtoby, N. P. and Bocchetta, M. and Yong, K. and Firth, N. C. and Cash, D. M. and Thomas, D. L. and others}, title = {{Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference}}, journal = {Nature communications}, year = {2018}, doi = {10.1038/s41467-018-05892-0}, pmid = {30323170}, url = {https://doi.org/10.1038/s41467-018-05892-0} } @article{mcgrath2017-29117954, author = {McGrath, E. R. and Beiser, A. S. and DeCarli, C. and Plourde, K. L. and Vasan, R. S. and Greenberg, S. M. and Seshadri, S.}, title = {{Blood pressure from mid- to late life and risk of incident dementia}}, journal = {Neurology}, year = {2017}, doi = {10.1212/wnl.0000000000004741}, pmid = {29117954}, url = {https://doi.org/10.1212/wnl.0000000000004741} } @article{song2021-34751136, author = {Song, T. and Song, X. and Zhu, C. and Patrick, R. and Skurla, M. and Santangelo, I. and Green, M. and Harper, D. and others}, title = {{Mitochondrial dysfunction, oxidative stress, neuroinflammation, and metabolic alterations in the progression of Alzheimer's disease: A meta-analysis of in vivo magnetic resonance spectroscopy studies}}, journal = {Ageing research reviews}, year = {2021}, doi = {10.1016/j.arr.2021.101503}, pmid = {34751136}, url = {https://doi.org/10.1016/j.arr.2021.101503} } @article{doraiswamy2012-22786606, author = {Doraiswamy, P. M. and Sperling, R. A. and Coleman, R. E. and Johnson, K. A. and Reiman, E. M. and Davis, M. D. and Grundman, M. and Sabbagh, M. N. and others}, title = {{Amyloid-β assessed by florbetapir F 18 PET and 18-month cognitive decline: a multicenter study}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e3182661f74}, pmid = {22786606}, url = {https://doi.org/10.1212/wnl.0b013e3182661f74} } @article{wolters2017-28588075, author = {Wolters, F. J. and Zonneveld, H. I. and Hofman, A. and van der Lugt, A. and Koudstaal, P. J. and Vernooij, M. W. and Ikram, M. A. and {Heart-Brain Connection Collaborative Research Group}}, title = {{Cerebral Perfusion and the Risk of Dementia: A Population-Based Study}}, journal = {Circulation}, year = {2017}, doi = {10.1161/circulationaha.117.027448}, pmid = {28588075}, url = {https://doi.org/10.1161/circulationaha.117.027448} } @article{licher2018-29740780, author = {Licher, S. and Yilmaz, P. and Leening, M. J. G. and Wolters, F. J. and Vernooij, M. W. and Stephan, B. C. M. and Ikram, M. K. and Ikram, M. A.}, title = {{External validation of four dementia prediction models for use in the general community-dwelling population: a comparative analysis from the Rotterdam Study}}, journal = {European journal of epidemiology}, year = {2018}, doi = {10.1007/s10654-018-0403-y}, pmid = {29740780}, url = {https://doi.org/10.1007/s10654-018-0403-y} } @article{meyerluehmann2008-18256671, author = {Meyer-Luehmann, M. and Spires-Jones, T. L. and Prada, C. and Garcia-Alloza, M. and de Calignon, A. and Rozkalne, A. and Koenigsknecht-Talboo, J. and Holtzman, D. M. and others}, title = {{Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease}}, journal = {Nature}, year = {2008}, doi = {10.1038/nature06616}, pmid = {18256671}, url = {https://doi.org/10.1038/nature06616} } @article{cohen2022-35140117, author = {Cohen, Ken and Ren, Sheng and Heath, Kevin and Dasmariñas, Micah C and Jubilo, Karol Giuseppe and Guo, Yinglong and Lipsitch, Marc and Daugherty, Sarah E.}, title = {{Risk of persistent and new clinical sequelae among adults aged 65 years and older during the post-acute phase of SARS-CoV-2 infection: retrospective cohort study}}, journal = {BMJ}, year = {2022}, doi = {10.1136/bmj-2021-068414}, pmid = {35140117}, url = {https://doi.org/10.1136/bmj-2021-068414} } @article{halabi2024-39666337, author = {Halabi, Cathra and Izzy, Saef and DiGiorgio, Anthony Michael and Mills, Hunter and Radmanesh, Farid and Yue, John K. and Choshali, Habibeh Ashouri and Schenk, Gundolf and others}, title = {{Traumatic Brain Injury and Risk of Incident Comorbidities}}, journal = {JAMA Network Open}, year = {2024}, doi = {10.1001/jamanetworkopen.2024.50499}, pmid = {39666337}, url = {https://doi.org/10.1001/jamanetworkopen.2024.50499} } @article{humbert2025-40167274, author = {Humbert, Marc and McLaughlin, Vallerie V. and Badesch, David B. and Ghofrani, Hossein Ardeschir and Gibbs, J. Simon R. and Gomberg‐Maitland, Mardi and Preston, Ioana R. and Souza, Rogério and others}, title = {{Sotatercept in Patients with Pulmonary Arterial Hypertension at High Risk for Death}}, journal = {New England Journal of Medicine}, year = {2025}, doi = {10.1056/nejmoa2415160}, pmid = {40167274}, url = {https://doi.org/10.1056/nejmoa2415160} } @article{chen2026-41604149, author = {Chen, Bowen and Xue, Erxu and Li, Yining and Tang, Enze and Wang, Yaojie and Wu, Yue and Liu, Shan and Zhao, Jianhui}, title = {{Life-Course Psychosocial Stress and Risk of Dementia and Stroke in Middle-Aged and Older Adults}}, journal = {JAMA Network Open}, year = {2026}, doi = {10.1001/jamanetworkopen.2025.56012}, pmid = {41604149}, url = {https://doi.org/10.1001/jamanetworkopen.2025.56012} } @article{noori2021-33347974, author = {Noori, A. and Mezlini, A. M. and Hyman, B. T. and Serrano-Pozo, A. and Das, S.}, title = {{Systematic review and meta-analysis of human transcriptomics reveals neuroinflammation, deficient energy metabolism, and proteostasis failure across neurodegeneration}}, journal = {Neurobiology of disease}, year = {2021}, doi = {10.1016/j.nbd.2020.105225}, pmid = {33347974}, url = {https://doi.org/10.1016/j.nbd.2020.105225} } @article{liu2023-36966451, author = {Liu, C. and Ma, Y. and Hofman, A. and Waziry, R. and Koton, S. and Pike, JR. and others}, title = {{Educational Attainment and Dementia: Mediation by Mid-Life Vascular Risk Factors}}, journal = {Annals of Neurology}, year = {2023}, doi = {10.1002/ana.26647}, pmid = {36966451}, url = {https://doi.org/10.1002/ana.26647} } @article{shen2026-41564649, author = {Shen, Jie and Chen, Hui and Gong, Yiying and Huang, Yuhui and Wu, Minyu and Gu, Yuxuan and Wang, Tian and Fontana, Luigi and others}, title = {{Association between plant-based diets and incident dementia: results from prospective cohort studies and a meta-analysis}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2026}, doi = {10.1016/j.tjpad.2025.100457}, pmid = {41564649}, url = {https://doi.org/10.1016/j.tjpad.2025.100457} } @article{capuano2025-41151002, author = {Capuano, A. W. and Bennett, D. A. and Dage, J. L. and Russ, K. A. and Arfanakis, K. and Lamar, M. and Barnes, L. L. and Schneider, J. A.}, title = {{Assessing Cognitive Decline and Dementia Risk in Black and White Older Adults With Blood Biomarkers pTau217, GFAP, NfL, and Aβ Ratio}}, journal = {Neurology}, year = {2025}, doi = {10.1212/WNL.0000000000214317}, pmid = {41151002}, url = {https://doi.org/10.1212/WNL.0000000000214317} } @article{buckley2019-30715078, author = {Buckley, R. F. and Mormino, E. C. and Rabin, J. S. and Hohman, T. J. and Landau, S. and Hanseeuw, B. J. and Jacobs, H. I. L. and Papp, K. V. and others}, title = {{Sex Differences in the Association of Global Amyloid and Regional Tau Deposition Measured by Positron Emission Tomography in Clinically Normal Older Adults}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2018.4693}, pmid = {30715078}, url = {https://doi.org/10.1001/jamaneurol.2018.4693} } @article{amariglio2015-25706191, author = {Amariglio, R. E. and Donohue, M. C. and Marshall, G. A. and Rentz, D. M. and Salmon, D. P. and Ferris, S. H. and Karantzoulis, S. and Aisen, P. S. and others}, title = {{Tracking early decline in cognitive function in older individuals at risk for Alzheimer disease dementia: the Alzheimer's Disease Cooperative Study Cognitive Function Instrument}}, journal = {JAMA neurology}, year = {2015}, doi = {10.1001/jamaneurol.2014.3375}, pmid = {25706191}, url = {https://doi.org/10.1001/jamaneurol.2014.3375} } @article{vandyck2019-31329216, author = {van Dyck, C. H. and Nygaard, H. B. and Chen, K. and Donohue, M. C. and Raman, R. and Rissman, R. A. and Brewer, J. B. and Koeppe, R. A. and others}, title = {{Effect of AZD0530 on Cerebral Metabolic Decline in Alzheimer Disease: A Randomized Clinical Trial}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2019.2050}, pmid = {31329216}, url = {https://doi.org/10.1001/jamaneurol.2019.2050} } @article{sevinc2021-34512305, author = {Sevinc, G. and Rusche, J. and Wong, B. and Datta, T. and Kaufman, R. and Gutz, S. E. and Schneider, M. and Todorova, N. and others}, title = {{Mindfulness Training Improves Cognition and Strengthens Intrinsic Connectivity Between the Hippocampus and Posteromedial Cortex in Healthy Older Adults}}, journal = {Frontiers in aging neuroscience}, year = {2021}, doi = {10.3389/fnagi.2021.702796}, pmid = {34512305}, url = {https://doi.org/10.3389/fnagi.2021.702796} } @article{viswanathan2009-19153374, author = {Viswanathan, A. and Raj, S. and Greenberg, S. M. and Stampfer, M. and Campbell, S. and Hyman, B. T. and Irizarry, M. C.}, title = {{Plasma Abeta, homocysteine, and cognition: the Vitamin Intervention for Stroke Prevention (VISP) trial}}, journal = {Neurology}, year = {2009}, doi = {10.1212/01.wnl.0000339486.63862.db}, pmid = {19153374}, url = {https://doi.org/10.1212/01.wnl.0000339486.63862.db} } @article{buckley2017-28592457, author = {Buckley, R. F. and Schultz, A. P. and Hedden, T. and Papp, K. V. and Hanseeuw, B. J. and Marshall, G. and Sepulcre, J. and Smith, E. E. and others}, title = {{Functional network integrity presages cognitive decline in preclinical Alzheimer disease}}, journal = {Neurology}, year = {2017}, doi = {10.1212/wnl.0000000000004059}, pmid = {28592457}, url = {https://doi.org/10.1212/wnl.0000000000004059} } @article{boeve2007-17412731, author = {Boeve, B. F. and Silber, M. H. and Saper, C. B. and Ferman, T. J. and Dickson, D. W. and Parisi, J. E. and Benarroch, E. E. and Ahlskog, J. E. and others}, title = {{Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease}}, journal = {Brain : a journal of neurology}, year = {2007}, doi = {10.1093/brain/awm056}, pmid = {17412731}, url = {https://doi.org/10.1093/brain/awm056} } @article{vandeerlin2010-20154673, author = {Van Deerlin, V. M. and Sleiman, P. M. and Martinez-Lage, M. and Chen-Plotkin, A. and Wang, L. S. and Graff-Radford, N. R. and Dickson, D. W. and Rademakers, R. and others}, title = {{Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions}}, journal = {Nature genetics}, year = {2010}, doi = {10.1038/ng.536}, pmid = {20154673}, url = {https://doi.org/10.1038/ng.536} } @article{kuo2005-15907742, author = {Kuo, H. K. and Yen, C. J. and Chang, C. H. and Kuo, C. K. and Chen, J. H. and Sorond, F.}, title = {{Relation of C-reactive protein to stroke, cognitive disorders, and depression in the general population: systematic review and meta-analysis}}, journal = {The Lancet. Neurology}, year = {2005}, doi = {10.1016/s1474-4422(05)70099-5}, pmid = {15907742}, url = {https://doi.org/10.1016/s1474-4422(05)70099-5} } @article{robinson2018-29878075, author = {Robinson, J. L. and Lee, E. B. and Xie, S. X. and Rennert, L. and Suh, E. and Bredenberg, C. and Caswell, C. and Van Deerlin, V. M. and others}, title = {{Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated}}, journal = {Brain : a journal of neurology}, year = {2018}, doi = {10.1093/brain/awy146}, pmid = {29878075}, url = {https://doi.org/10.1093/brain/awy146} } @article{lee2019-30760848, author = {Lee, G. and Nho, K. and Kang, B. and Sohn, K. A. and Kim, D. and {for Alzheimer’s Disease Neuroimaging Initiative}}, title = {{Predicting Alzheimer's disease progression using multi-modal deep learning approach}}, journal = {Scientific reports}, year = {2019}, doi = {10.1038/s41598-018-37769-z}, pmid = {30760848}, url = {https://doi.org/10.1038/s41598-018-37769-z} } @article{liu2017-28629879, author = {Liu, G. and Locascio, J. J. and Corvol, J. C. and Boot, B. and Liao, Z. and Page, K. and Franco, D. and Burke, K. and others}, title = {{Prediction of cognition in Parkinson's disease with a clinical-genetic score: a longitudinal analysis of nine cohorts}}, journal = {The Lancet. Neurology}, year = {2017}, doi = {10.1016/s1474-4422(17)30122-9}, pmid = {28629879}, url = {https://doi.org/10.1016/s1474-4422(17)30122-9} } @article{marden2017-28541410, author = {Marden, JR. and Tchetgen Tchetgen, E. J. and Kawachi, I. and Glymour, M. M.}, title = {{Contribution of Socioeconomic Status at 3 Life-Course Periods to Late-Life Memory Function and Decline: Early and Late Predictors of Dementia Risk}}, journal = {American journal of epidemiology}, year = {2017}, doi = {10.1093/aje/kwx155}, pmid = {28541410}, url = {https://doi.org/10.1093/aje/kwx155} } @article{kivisakk2026-41610380, author = {Kivisäkk, Pia and Fatima, Hadia A. and Wu, Chao‐Yi and Padmanabhan, Nikhil and Romero, Daniel and Gorham, Taron and Weik, Molly and Dodge, Hiroko H. and others}, title = {{Postmortem Associations Between Alzheimer Disease Pathology and Plasma pTau217, GFAP, and NfL in AD and AD-Related Dementias}}, journal = {Neurology}, year = {2026}, doi = {10.1212/wnl.0000000000214351}, pmid = {41610380}, url = {https://doi.org/10.1212/wnl.0000000000214351} } @article{li2025-39813632, author = {Li, Yuhan and Li, Yanping and Gu, Xiao and Liu, Yuxi and Dong, Danyue and Kang, Jae Hee and Wang, Molin and Eliassen, A. Heather and others}, title = {{Long-Term Intake of Red Meat in Relation to Dementia Risk and Cognitive Function in US Adults}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000210286}, pmid = {39813632}, url = {https://doi.org/10.1212/wnl.0000000000210286} } @article{ni2025-41327300, author = {Ni, Jiaqi and Hernández-Cacho, Adrián and Nishi, Stephanie K. and Babió, Nancy and Belzer, Clara and Konstati, Prokopis and Vioqué, Jesús and Corella, Dolores and others}, title = {{Mediterranean diet, gut microbiota, and cognitive decline in older adults with obesity/overweight and metabolic syndrome: a prospective cohort study}}, journal = {BMC Medicine}, year = {2025}, doi = {10.1186/s12916-025-04488-y}, pmid = {41327300}, url = {https://doi.org/10.1186/s12916-025-04488-y} } @article{lambert2013-24162737, author = {Lambert, Jean‐Charles and Ibrahim‐Verbaas, Carla A. and Harold, Denise H. and Naj, Adam Christian and Sims, Rebecca and Bellenguez, Céline and others}, title = {{Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease}}, journal = {Nature Genetics}, year = {2013}, doi = {10.1038/ng.2802}, pmid = {24162737}, url = {https://doi.org/10.1038/ng.2802} } @article{dubois2014-24849862, author = {Dubois, Bruno and Feldman, Howard and Jacova, Claudia and Hampel, Harald Juergen and Molinuevo, José Luís and Blennow, Kaj and DeKosky, Steven T. and Gauthier, Serge G. and others}, title = {{Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria}}, journal = {The Lancet Neurology}, year = {2014}, doi = {10.1016/s1474-4422(14)70090-0}, pmid = {24849862}, url = {https://doi.org/10.1016/s1474-4422(14)70090-0} } @article{chen2026-42160746, author = {Chen, H. and Wang, J. and Lai, S. and Peng, G. and Zong, G. and Yuan, C. and others}, title = {{Smoking Cessation, Weight Change, and Risk of Dementia: A Prospective Cohort Study}}, journal = {Neurology}, year = {2026}, doi = {10.1212/WNL.0000000000218123}, pmid = {42160746}, url = {https://doi.org/10.1212/WNL.0000000000218123} } @article{shi2017-28959956, author = {Shi, Y. and Yamada, K. and Liddelow, S. A. and Smith, S. T. and Zhao, L. and Luo, W. and Tsai, R. M. and Spina, S. and others}, title = {{ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy}}, journal = {Nature}, year = {2017}, doi = {10.1038/nature24016}, pmid = {28959956}, url = {https://doi.org/10.1038/nature24016} } @article{donohue2014-24886908, author = {Donohue, M. C. and Sperling, R. A. and Salmon, D. P. and Rentz, D. M. and Raman, R. and Thomas, R. G. and Weiner, M. and Aisen, P. S. and others}, title = {{The preclinical Alzheimer cognitive composite: measuring amyloid-related decline}}, journal = {JAMA neurology}, year = {2014}, doi = {10.1001/jamaneurol.2014.803}, pmid = {24886908}, url = {https://doi.org/10.1001/jamaneurol.2014.803} } @article{vermunt2019-31164314, author = {Vermunt, L. and Sikkes, S. A. M. and van den Hout, A. and Handels, R. and Bos, I. and van der Flier, W. M. and Kern, S. and Ousset, P. J. and others}, title = {{Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2019}, doi = {10.1016/j.jalz.2019.04.001}, pmid = {31164314}, url = {https://doi.org/10.1016/j.jalz.2019.04.001} } @article{mormino2014-24748674, author = {Mormino, E. C. and Betensky, R. A. and Hedden, T. and Schultz, A. P. and Ward, A. and Huijbers, W. and Rentz, D. M. and Johnson, K. A. and others}, title = {{Amyloid and APOE ε4 interact to influence short-term decline in preclinical Alzheimer disease}}, journal = {Neurology}, year = {2014}, doi = {10.1212/wnl.0000000000000431}, pmid = {24748674}, url = {https://doi.org/10.1212/wnl.0000000000000431} } @article{zhang2008-18192497, author = {Zhang, B. and Mitchell, S. L. and Bambauer, K. Z. and Jones, R. and Prigerson, H. G.}, title = {{Depressive symptom trajectories and associated risks among bereaved Alzheimer disease caregivers}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2008}, doi = {10.1097/jgp.0b013e318157caec}, pmid = {18192497}, url = {https://doi.org/10.1097/jgp.0b013e318157caec} } @article{rentz2024-39044489, author = {Rentz, D. M. and Rosenberg, P. B. and Sperling, R. A. and Donohue, M. C. and Raman, R. and Liu, A. and Aisen, P. S.}, title = {{Characterizing Clinical Progression in Cognitively Unimpaired Older Individuals with Brain Amyloid: Results from the A4 Study}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2024}, doi = {10.14283/jpad.2024.123}, pmid = {39044489}, url = {https://doi.org/10.14283/jpad.2024.123} } @article{rascovsky2011-21810890, author = {Rascovsky, K. and Hodges, JR. and Knopman, D. and Mendez, M. F. and Kramer, J. H. and Neuhaus, J. and van Swieten, J. C. and Seelaar, H. and others}, title = {{Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia}}, journal = {Brain : a journal of neurology}, year = {2011}, doi = {10.1093/brain/awr179}, pmid = {21810890}, url = {https://doi.org/10.1093/brain/awr179} } @article{volandes2011-21254815, author = {Volandes, A. E. and Ferguson, L. A. and Davis, A. D. and Hull, N. C. and Green, M. J. and Chang, Y. and Deep, K. and Paasche-Orlow, M. K.}, title = {{Assessing end-of-life preferences for advanced dementia in rural patients using an educational video: a randomized controlled trial}}, journal = {Journal of palliative medicine}, year = {2011}, doi = {10.1089/jpm.2010.0299}, pmid = {21254815}, url = {https://doi.org/10.1089/jpm.2010.0299} } @article{tranah2011-22162057, author = {Tranah, G. J. and Blackwell, T. and Stone, K. L. and Ancoli-Israel, S. and Paudel, M. L. and Ensrud, K. E. and Cauley, J. A. and Redline, S. and others}, title = {{Circadian activity rhythms and risk of incident dementia and mild cognitive impairment in older women}}, journal = {Annals of neurology}, year = {2011}, doi = {10.1002/ana.22468}, pmid = {22162057}, url = {https://doi.org/10.1002/ana.22468} } @article{freeman2006-17194275, author = {Freeman, M. P. and Hibbeln, JR. and Wisner, K. L. and Davis, J. M. and Mischoulon, D. and Peet, M. and Keck, P. E. and Marangell, L. B. and others}, title = {{Omega-3 fatty acids: evidence basis for treatment and future research in psychiatry}}, journal = {The Journal of clinical psychiatry}, year = {2006}, doi = {10.4088/jcp.v67n1217}, pmid = {17194275}, url = {https://doi.org/10.4088/jcp.v67n1217} } @article{racine2021-33078300, author = {Racine, A. M. and Tommet, D. and D'Aquila, M. L. and Fong, T. G. and Gou, Y. and Tabloski, P. A. and Metzger, E. D. and Hshieh, T. T. and others}, title = {{Machine Learning to Develop and Internally Validate a Predictive Model for Post-operative Delirium in a Prospective, Observational Clinical Cohort Study of Older Surgical Patients}}, journal = {Journal of general internal medicine}, year = {2021}, doi = {10.1007/s11606-020-06238-7}, pmid = {33078300}, url = {https://doi.org/10.1007/s11606-020-06238-7} } @article{weiner2017-28342697, author = {Weiner, M. W. and Veitch, D. P. and Aisen, P. S. and Beckett, L. A. and Cairns, N. J. and Green, R. C. and Harvey, D. and Jack, C. R. and others}, title = {{Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2017}, doi = {10.1016/j.jalz.2016.11.007}, pmid = {28342697}, url = {https://doi.org/10.1016/j.jalz.2016.11.007} } @article{jefferson2015-25700178, author = {Jefferson, A. L. and Beiser, A. S. and Himali, J. J. and Seshadri, S. and O'Donnell, C. J. and Manning, W. J. and Wolf, P. A. and Au, R. and others}, title = {{Low cardiac index is associated with incident dementia and Alzheimer disease: the Framingham Heart Study}}, journal = {Circulation}, year = {2015}, doi = {10.1161/circulationaha.114.012438}, pmid = {25700178}, url = {https://doi.org/10.1161/circulationaha.114.012438} } @article{mauschitz2018-29716786, author = {Mauschitz, M. M. and Bonnemaijer, P. W. M. and Diers, K. and Rauscher, F. G. and Elze, T. and Engel, C. and Loeffler, M. and Colijn, J. M. and others}, title = {{Systemic and Ocular Determinants of Peripapillary Retinal Nerve Fiber Layer Thickness Measurements in the European Eye Epidemiology (E3) Population}}, journal = {Ophthalmology}, year = {2018}, doi = {10.1016/j.ophtha.2018.03.026}, pmid = {29716786}, url = {https://doi.org/10.1016/j.ophtha.2018.03.026} } @article{assogna2023-37500561, author = {Assogna, M. and Premi, E. and Gazzina, S. and Benussi, A. and Ashton, N. J. and Zetterberg, H. and Blennow, K. and Gasparotti, R. and others}, title = {{Association of Choroid Plexus Volume With Serum Biomarkers, Clinical Features, and Disease Severity in Patients With Frontotemporal Lobar Degeneration Spectrum}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000207600}, pmid = {37500561}, url = {https://doi.org/10.1212/wnl.0000000000207600} } @article{mitchell2005-15673356, author = {Mitchell, Susan L. and Teno, Joan M. and Miller, Susan C. and Mor, Vincent}, title = {{A National Study of the Location of Death for Older Persons with Dementia}}, journal = {Journal of the American Geriatrics Society}, year = {2005}, doi = {10.1111/j.1532-5415.2005.53118.x}, pmid = {15673356}, url = {https://doi.org/10.1111/j.1532-5415.2005.53118.x} } @article{kolo2025-41191359, author = {Kolo, Francis Babaman and Lu, Sophia Francesca DP and Beiser, Alexa S. and Francis, Lily and van Lent, Debora Melo and Gireud, Monica and Himali, Jayandra Jung and Ghosh, Saptaparni and others}, title = {{Hearing Loss, Brain Structure, Cognition, and Dementia Risk in the Framingham Heart Study}}, journal = {JAMA Network Open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.39209}, pmid = {41191359}, url = {https://doi.org/10.1001/jamanetworkopen.2025.39209} } @article{aguilerabuenosvinos2025-39998833, author = {Aguilera-Buenosvinos, Inmaculada and Berstein, Fernanda Morales and González‐Gil, Esther M. and Dossus, Laure and Gunter, Marc James and Biessy, Carine and Masala, Giovanna and de Magistris, Maria Santucci and others}, title = {{Adherence to the Mediterranean Diet and Obesity-Linked Cancer Risk in EPIC}}, journal = {JAMA Network Open}, year = {2025}, doi = {10.1001/jamanetworkopen.2024.61031}, pmid = {39998833}, url = {https://doi.org/10.1001/jamanetworkopen.2024.61031} } @article{bian2025-39920677, author = {Bian, Wenxin and Biswas, Raaj Kishore and Ahmadi, Matthew N. and Bin, Yu Sun and Postnova, Svetlana and Phillips, Andrew J. K. and Koemel, Nicholas A. and Chaput, Jean‐Philippe and others}, title = {{Dose-response associations of device-measured sleep regularity and duration with incident dementia in 82391 UK adults}}, journal = {BMC Public Health}, year = {2025}, doi = {10.1186/s12889-025-21649-z}, pmid = {39920677}, url = {https://doi.org/10.1186/s12889-025-21649-z} } @article{hardy2002-12130773, author = {Hardy, John and Selkoe, Dennis J.}, title = {{The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics}}, journal = {Science}, year = {2002}, doi = {10.1126/science.1072994}, pmid = {12130773}, url = {https://doi.org/10.1126/science.1072994} } @article{hooli2014-25186855, author = {Hooli, B. V. and Parrado, A. R. and Mullin, K. and Yip, W. K. and Liu, T. and Roehr, J. T. and Qiao, D. and Jessen, F. and others}, title = {{The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk}}, journal = {Neurology}, year = {2014}, doi = {10.1212/wnl.0000000000000855}, pmid = {25186855}, url = {https://doi.org/10.1212/wnl.0000000000000855} } @article{hong2016-27033548, author = {Hong, S. and Beja-Glasser, V. F. and Nfonoyim, B. M. and Frouin, A. and Li, S. and Ramakrishnan, S. and Merry, K. M. and Shi, Q. and others}, title = {{Complement and microglia mediate early synapse loss in Alzheimer mouse models}}, journal = {Science (New York, N.Y.)}, year = {2016}, doi = {10.1126/science.aad8373}, pmid = {27033548}, url = {https://doi.org/10.1126/science.aad8373} } @article{janelidze2022-35789365, author = {Janelidze, S. and Christian, B. T. and Price, J. and Laymon, C. and Schupf, N. and Klunk, W. E. and Lott, I. and Silverman, W. and others}, title = {{Detection of Brain Tau Pathology in Down Syndrome Using Plasma Biomarkers}}, journal = {JAMA neurology}, year = {2022}, doi = {10.1001/jamaneurol.2022.1740}, pmid = {35789365}, url = {https://doi.org/10.1001/jamaneurol.2022.1740} } @article{ge2018-29592889, author = {Ge, T. and Sabuncu, M. R. and Smoller, J. W. and Sperling, R. A. and Mormino, E. C. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{Dissociable influences of APOE ε4 and polygenic risk of AD dementia on amyloid and cognition}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000005415}, pmid = {29592889}, url = {https://doi.org/10.1212/wnl.0000000000005415} } @article{friedman2013-23689947, author = {Friedman, S. D. and Baker, L. D. and Borson, S. and Jensen, J. E. and Barsness, S. M. and Craft, S. and Merriam, G. R. and Otto, R. K. and others}, title = {{Growth hormone-releasing hormone effects on brain γ-aminobutyric acid levels in mild cognitive impairment and healthy aging}}, journal = {JAMA neurology}, year = {2013}, doi = {10.1001/jamaneurol.2013.1425}, pmid = {23689947}, url = {https://doi.org/10.1001/jamaneurol.2013.1425} } @article{atri2011-21555634, author = {Atri, A. and O'Brien, J. L. and Sreenivasan, A. and Rastegar, S. and Salisbury, S. and DeLuca, A. N. and O'Keefe, K. M. and LaViolette, P. S. and others}, title = {{Test-retest reliability of memory task functional magnetic resonance imaging in Alzheimer disease clinical trials}}, journal = {Archives of neurology}, year = {2011}, doi = {10.1001/archneurol.2011.94}, pmid = {21555634}, url = {https://doi.org/10.1001/archneurol.2011.94} } @article{mace2024-39571150, author = {Mace, R. A. and Law, M. E. and Cohen, J. E. and Ritchie, C. S. and Okereke, O. I. and Hoeppner, B. B. and Brewer, J. A. and Bartels, S. J. and others}, title = {{A Mindfulness-Based Lifestyle Intervention for Dementia Risk Reduction: Protocol for the My Healthy Brain Feasibility Randomized Controlled Trial}}, journal = {JMIR research protocols}, year = {2024}, doi = {10.2196/64149}, pmid = {39571150}, url = {https://doi.org/10.2196/64149} } @article{saif2020-32665410, author = {Saif, N. and Niotis, K. and Dominguez, M. and Hodes, J. F. and Woodbury, M. and Amini, Y. and Sadek, G. and Scheyer, O. and others}, title = {{Education Research: Online Alzheimer education for high school and college students: A randomized controlled trial}}, journal = {Neurology}, year = {2020}, doi = {10.1212/wnl.0000000000009859}, pmid = {32665410}, url = {https://doi.org/10.1212/wnl.0000000000009859} } @article{marcantonio2014-25329203, author = {Marcantonio, E. R. and Ngo, L. H. and O'Connor, M. and Jones, R. N. and Crane, P. K. and Metzger, E. D. and Inouye, S. K.}, title = {{3D-CAM: derivation and validation of a 3-minute diagnostic interview for CAM-defined delirium: a cross-sectional diagnostic test study}}, journal = {Annals of internal medicine}, year = {2014}, doi = {10.7326/m14-0865}, pmid = {25329203}, url = {https://doi.org/10.7326/m14-0865} } @article{dickerson2011-21490323, author = {Dickerson, B. C. and Stoub, T. R. and Shah, R. C. and Sperling, R. A. and Killiany, R. J. and Albert, M. S. and Hyman, B. T. and Blacker, D. and others}, title = {{Alzheimer-signature MRI biomarker predicts AD dementia in cognitively normal adults}}, journal = {Neurology}, year = {2011}, doi = {10.1212/wnl.0b013e3182166e96}, pmid = {21490323}, url = {https://doi.org/10.1212/wnl.0b013e3182166e96} } @article{shi2023-36574646, author = {Shi, L. and Zhu, Q. and Wang, Y. and Hao, H. and Zhang, H. and Schwartz, J. and Amini, H. and van Donkelaar, A. and others}, title = {{Incident dementia and long-term exposure to constituents of fine particle air pollution: A national cohort study in the United States}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2023}, doi = {10.1073/pnas.2211282119}, pmid = {36574646}, url = {https://doi.org/10.1073/pnas.2211282119} } @article{slot2019-30555032, author = {Slot, R. E. R. and Sikkes, S. A. M. and Berkhof, J. and Brodaty, H. and Buckley, R. and Cavedo, E. and Dardiotis, E. and Guillo-Benarous, F. and others}, title = {{Subjective cognitive decline and rates of incident Alzheimer's disease and non-Alzheimer's disease dementia}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2019}, doi = {10.1016/j.jalz.2018.10.003}, pmid = {30555032}, url = {https://doi.org/10.1016/j.jalz.2018.10.003} } @article{montine2012-22101365, author = {Montine, T. J. and Phelps, C. H. and Beach, T. G. and Bigio, E. H. and Cairns, N. J. and Dickson, D. W. and Duyckaerts, C. and Frosch, M. P. and others}, title = {{National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach}}, journal = {Acta neuropathologica}, year = {2012}, doi = {10.1007/s00401-011-0910-3}, pmid = {22101365}, url = {https://doi.org/10.1007/s00401-011-0910-3} } @article{brown2022-35197628, author = {Brown, A. L. and Wilkins, O. G. and Keuss, M. J. and Kargbo-Hill, S. E. and Zanovello, M. and Lee, W. C. and Bampton, A. and Lee, F. C. Y. and others}, title = {{TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A}}, journal = {Nature}, year = {2022}, doi = {10.1038/s41586-022-04436-3}, pmid = {35197628}, url = {https://doi.org/10.1038/s41586-022-04436-3} } @article{beecham2014-25188341, author = {Beecham, G. W. and Hamilton, K. and Naj, A. C. and Martin, E. R. and Huentelman, M. and Myers, A. J. and Corneveaux, J. J. and Hardy, J. and others}, title = {{Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias}}, journal = {PLoS genetics}, year = {2014}, doi = {10.1371/journal.pgen.1004606}, pmid = {25188341}, url = {https://doi.org/10.1371/journal.pgen.1004606} } @article{llibreguerra2019-31825500, author = {Llibre-Guerra, J. J. and Li, Y. and Schindler, S. E. and Gordon, B. A. and Fagan, A. M. and Morris, J. C. and Benzinger, T. L. S. and Hassenstab, J. and others}, title = {{Association of Longitudinal Changes in Cerebrospinal Fluid Total Tau and Phosphorylated Tau 181 and Brain Atrophy With Disease Progression in Patients With Alzheimer Disease}}, journal = {JAMA network open}, year = {2019}, doi = {10.1001/jamanetworkopen.2019.17126}, pmid = {31825500}, url = {https://doi.org/10.1001/jamanetworkopen.2019.17126} } @article{devore2010-20625087, author = {Devore, E. E. and Grodstein, F. and van Rooij, F. J. and Hofman, A. and Stampfer, M. J. and Witteman, J. C. and Breteler, M. M.}, title = {{Dietary antioxidants and long-term risk of dementia}}, journal = {Archives of neurology}, year = {2010}, doi = {10.1001/archneurol.2010.144}, pmid = {20625087}, url = {https://doi.org/10.1001/archneurol.2010.144} } @article{gamberger2017-28755001, author = {Gamberger, D. and Lavrač, N. and Srivatsa, S. and Tanzi, R. E. and Doraiswamy, P. M.}, title = {{Identification of clusters of rapid and slow decliners among subjects at risk for Alzheimer's disease}}, journal = {Scientific reports}, year = {2017}, doi = {10.1038/s41598-017-06624-y}, pmid = {28755001}, url = {https://doi.org/10.1038/s41598-017-06624-y} } @article{yiallourou2025-40377976, author = {Yiallourou, Stephanie R and Baril, Andrée‐Ann and Wiedner, Crystal and Misialek, Jeffrey R. and Kline, Christopher E. and Harrison, Stephanie Litwack and Cannon, Ethan J. and Yang, Qiong and others}, title = {{Sleep architecture and dementia risk in adults: an analysis of 5 cohorts from the Sleep and Dementia Consortium}}, journal = {SLEEP}, year = {2025}, doi = {10.1093/sleep/zsaf129}, pmid = {40377976}, url = {https://doi.org/10.1093/sleep/zsaf129} } @article{wang2025-40266617, author = {Wang, Jingxuan and Choi, Minhyuk and Buto, Peter T. and Kelly, John Daniel and La Joie, Renaud and Kornak, John and Zimmerman, Scott C. and Chen, Ruijia and others}, title = {{Detection Bias in EHR-Based Research on Clinical Exposures and Dementia}}, journal = {JAMA Network Open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.6637}, pmid = {40266617}, url = {https://doi.org/10.1001/jamanetworkopen.2025.6637} } @article{thapa2026-41495409, author = {Thapa, Rahul and Kjær, Magnus Ruud and He, Bryan D. and Covert, Ian and Moore, Hyatt E. and Hanif, Umaer and Ganjoo, Gauri and Westover, Michael Brandon and others}, title = {{A multimodal sleep foundation model for disease prediction}}, journal = {Nature Medicine}, year = {2026}, doi = {10.1038/s41591-025-04133-4}, pmid = {41495409}, url = {https://doi.org/10.1038/s41591-025-04133-4} } @article{greenberg2025-40977537, author = {Greenberg, Steven Mark and Albert, Marylin S. and An, Hongyu and Arfanakis, Konstantinos and Evia, Arnold Moya and Caprihan, Arvind and Ford, Andria L. and Fornage, Myriam and others}, title = {{MarkVCID2 Consortium for Clinical Validation of Biomarkers of Cerebral Small Vessel Disease: Validation Framework and Baseline Characteristics}}, journal = {Annals of Neurology}, year = {2025}, doi = {10.1002/ana.78040}, pmid = {40977537}, url = {https://doi.org/10.1002/ana.78040} } @article{heneka2015-25792098, author = {Heneka, Michael Thomas and Carson, Monica J. and El Khoury, Joseph B. and Landreth, Gary E. and Brosseron, Frederic and Feinstein, Douglas L. and Jacobs, Andreas Hans and Wyss‐Coray, Tony and others}, title = {{Neuroinflammation in Alzheimer's disease}}, journal = {The Lancet Neurology}, year = {2015}, doi = {10.1016/s1474-4422(15)70016-5}, pmid = {25792098}, url = {https://doi.org/10.1016/s1474-4422(15)70016-5} } @article{sherrington1995-7596406, author = {Sherrington, Robin P. and Rogaev, Evgeny Ivanovich and Liang, Yuh‐Jin and Rogaeva, Ekaterina A. and Lévesque, Georges and Ikeda, Masaki and Chi, H. and Lin, Chiao‐Feng and others}, title = {{Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease}}, journal = {Nature}, year = {1995}, doi = {10.1038/375754a0}, pmid = {7596406}, url = {https://doi.org/10.1038/375754a0} } @article{vassar1999-10531052, author = {Vassar, Robert J. and Bennett, Brian D. and Babu‐Khan, Safura and Kahn, Steve and Mendiaz, Elizabeth A. and Denis, Paul E. and Teplow, David B. and Ross, Sandra L. and others}, title = {{β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE}}, journal = {Science}, year = {1999}, doi = {10.1126/science.286.5440.735}, pmid = {10531052}, url = {https://doi.org/10.1126/science.286.5440.735} } @article{mathys2019-31042697, author = {Mathys, Hansruedi and Dávila-Velderrain, José and Peng, Zhuyu and Gao, Fan and Mohammadi, Shahin and Young, Jennie Z. and Menon, Madhvi and He, Liang and Abdurrob, Fatema and Jiang, Xueqiao and Martorell, Anthony J. and Ransohoff, Richard M. and Hafler, Brian P. and Bennett, David Alan and Kellis, Manolis and Tsai, Li‐Huei}, title = {{Single-cell transcriptomic analysis of Alzheimer’s disease}}, journal = {Nature}, year = {2019}, doi = {10.1038/s41586-019-1195-2}, pmid = {31042697}, url = {https://doi.org/10.1038/s41586-019-1195-2} } @article{page2021-33782057, author = {Page, Matthew James and McKenzie, Joanne E. and Bossuyt, Patrick M. and Boutron, Isabelle and Hoffmann, Tammy and Mulrow, Cynthia D. and Shamseer, Larissa and Tetzlaff, Jennifer and Akl, Elie A. and Brennan, Sue and Chou, Roger and Glanville, Julie and Grimshaw, Jeremy and Hróbjartsson, Asbjørn and Lalu, Manoj Mathew and Li, Tianjing and Loder, Elizabeth and Mayo‐Wilson, Evan and McDonald, Steve J and McGuinness, Luke A. and Stewart, Lesley A. and Thomas, James and Tricco, Andrea C. and Welch, Vivian Andrea and Whiting, Penny F. and Moher, David}, title = {{The PRISMA 2020 statement: an updated guideline for reporting systematic reviews}}, journal = {BMJ}, year = {2021}, doi = {10.1136/bmj.n71}, pmid = {33782057}, url = {https://doi.org/10.1136/bmj.n71} } @article{duering2023-37236211, author = {Duering, Marco and Biessels, Geert Jan and Brodtmann, Amy G. and Chen, Christopher and Cordonnier, Charlotte and de Leeuw, Frank‐Erik and Debette, Stéphanie and Frayne, Richard and Jouvent, Éric and Rost, Natalia S. and ter Telgte, Annemieke and Salman, Rustam Al‐Shahi and Backes, Walter H. and Bae, Hee‐Joon and Brown, Rosalind and Chabriat, Hugues and De Luca, Alberto and DeCarli, Charles S and Dewenter, Anna and Doubal, Fergus and Ewers, Michael and Field, Thalia Shoshana and Ganesh, Aravind and Greenberg, Steven Mark and Helmer, Karl G. and Hilal, Saima and Jochems, Angela C.C. and Jokinen, Hanna and Kuijf, Hugo J. and Lam, Bonnie Y. K. and Lebenberg, Jessica and MacIntosh, Bradley John and Maillard, Pauline and Mok, Vincent and Pantoni, Leonardo and Rudilosso, Salvatore and Satizábal, Claudia Liliana and Schirmer, Markus D. and Schmidt, Reinhold and Smith, Colin and Staals, Julie and Thrippleton, Michael J. and van Veluw, Susanne J. and Vemuri, Prashanthi and Wang, Yilong and Werring, David John and Zedde, Marialuisa and Akinyemi, Rufus and Del Brutto, Óscar H. and Markus, Hugh Stephen and Zhu, Yi‐Cheng and Smith, Eric Edward and Dichgans, Martin and Wardlaw, Joanna Marguerite}, title = {{Neuroimaging standards for research into small vessel disease—advances since 2013}}, journal = {The Lancet Neurology}, year = {2023}, doi = {10.1016/s1474-4422(23)00131-x}, pmid = {37236211}, url = {https://doi.org/10.1016/s1474-4422(23)00131-x} } @article{vandyck2025-41355080, author = {van Dyck, C. H. and Sperling, R. and Johnson, K. and Dhadda, S. and Kanekiyo, M. and Li, D. and Gee, M. and Hersch, S. and Irizarry, M. and Kramer, L.}, title = {{Long-term safety and efficacy of lecanemab in early Alzheimer's disease: Results from the Clarity AD open-label extension study}}, journal = {Alzheimer's \& Dementia}, year = {2025}, doi = {10.1002/alz.70905}, pmid = {41355080}, url = {https://doi.org/10.1002/alz.70905} } @article{atri2026-42128444, author = {Atri, A. and Apostolova, L. G. and Iwata, A. and Wessels, A. M. and Atkins, A. and Lu, M. and Ye, W. and Ryan, S. and Doty, E. G.}, title = {{Clinical Meaningfulness of Donanemab in Early Symptomatic Alzheimer Disease: Data From the Randomized Phase 3 TRAILBLAZER-ALZ 2 Trial}}, journal = {Neurology: Clinical Practice}, year = {2026}, doi = {10.1212/CPJ.0000000000200621}, pmid = {42128444}, url = {https://doi.org/10.1212/CPJ.0000000000200621} } @article{quiroz2020-32470423, author = {Quiroz, Y. T. and Zetterberg, H. and Reiman, E. M. and Chen, Y. and Su, Y. and Fox-Fuller, J. T. and Garcia, G. and Villegas, A. and others}, title = {{Plasma neurofilament light chain in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional and longitudinal cohort study}}, journal = {The Lancet. Neurology}, year = {2020}, doi = {10.1016/s1474-4422(20)30137-x}, pmid = {32470423}, url = {https://doi.org/10.1016/s1474-4422(20)30137-x} } @article{young2022-35435938, author = {Young, C. B. and Winer, JR. and Younes, K. and Cody, K. A. and Betthauser, T. J. and Johnson, S. C. and Schultz, A. and Sperling, R. A. and others}, title = {{Divergent Cortical Tau Positron Emission Tomography Patterns Among Patients With Preclinical Alzheimer Disease}}, journal = {JAMA neurology}, year = {2022}, doi = {10.1001/jamaneurol.2022.0676}, pmid = {35435938}, url = {https://doi.org/10.1001/jamaneurol.2022.0676} } @article{hofmann2024-39557867, author = {Hofmann, A. and Häsler, L. M. and Lambert, M. and Kaeser, S. A. and Gräber-Sultan, S. and Obermüller, U. and Kuder-Buletta, E. and la Fougere, C. and others}, title = {{Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer's disease}}, journal = {Nature communications}, year = {2024}, doi = {10.1038/s41467-024-52937-8}, pmid = {39557867}, url = {https://doi.org/10.1038/s41467-024-52937-8} } @article{obrien2010-20463288, author = {O'Brien, J. L. and O'Keefe, K. M. and LaViolette, P. S. and DeLuca, A. N. and Blacker, D. and Dickerson, B. C. and Sperling, R. A.}, title = {{Longitudinal fMRI in elderly reveals loss of hippocampal activation with clinical decline}}, journal = {Neurology}, year = {2010}, doi = {10.1212/wnl.0b013e3181e3966e}, pmid = {20463288}, url = {https://doi.org/10.1212/wnl.0b013e3181e3966e} } @article{qian2017-28323826, author = {Qian, J. and Wolters, F. J. and Beiser, A. and Haan, M. and Ikram, M. A. and Karlawish, J. and Langbaum, J. B. and Neuhaus, J. M. and others}, title = {{APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts}}, journal = {PLoS medicine}, year = {2017}, doi = {10.1371/journal.pmed.1002254}, pmid = {28323826}, url = {https://doi.org/10.1371/journal.pmed.1002254} } @article{reiman2012-23137948, author = {Reiman, E. M. and Quiroz, Y. T. and Fleisher, A. S. and Chen, K. and Velez-Pardo, C. and Jimenez-Del-Rio, M. and Fagan, A. M. and Shah, A. R. and others}, title = {{Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study}}, journal = {The Lancet. Neurology}, year = {2012}, doi = {10.1016/s1474-4422(12)70228-4}, pmid = {23137948}, url = {https://doi.org/10.1016/s1474-4422(12)70228-4} } @article{licher2019-31451782, author = {Licher, S. and Ahmad, S. and Karamujić-Čomić, H. and Voortman, T. and Leening, M. J. G. and Ikram, M. A. and Ikram, M. K.}, title = {{Genetic predisposition, modifiable-risk-factor profile and long-term dementia risk in the general population}}, journal = {Nature medicine}, year = {2019}, doi = {10.1038/s41591-019-0547-7}, pmid = {31451782}, url = {https://doi.org/10.1038/s41591-019-0547-7} } @article{christakis2006-16481639, author = {Christakis, N. A. and Allison, P. D.}, title = {{Mortality after the hospitalization of a spouse}}, journal = {The New England journal of medicine}, year = {2006}, doi = {10.1056/nejmsa050196}, pmid = {16481639}, url = {https://doi.org/10.1056/nejmsa050196} } @article{johnson2013-23375563, author = {Johnson, K. A. and Sperling, R. A. and Gidicsin, C. M. and Carmasin, J. S. and Maye, J. E. and Coleman, R. E. and Reiman, E. M. and Sabbagh, M. N. and others}, title = {{Florbetapir (F18-AV-45) PET to assess amyloid burden in Alzheimer's disease dementia, mild cognitive impairment, and normal aging}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2013}, doi = {10.1016/j.jalz.2012.10.007}, pmid = {23375563}, url = {https://doi.org/10.1016/j.jalz.2012.10.007} } @article{atherton2022-35759276, author = {Atherton, K. and Han, X. and Chung, J. and Cherry, J. D. and Baucom, Z. and Saltiel, N. and Nair, E. and Abdolmohammadi, B. and others}, title = {{Association of APOE Genotypes and Chronic Traumatic Encephalopathy}}, journal = {JAMA neurology}, year = {2022}, doi = {10.1001/jamaneurol.2022.1634}, pmid = {35759276}, url = {https://doi.org/10.1001/jamaneurol.2022.1634} } @article{marcantonio2000-10855596, author = {Marcantonio, E. R. and Flacker, J. M. and Michaels, M. and Resnick, N. M.}, title = {{Delirium is independently associated with poor functional recovery after hip fracture}}, journal = {Journal of the American Geriatrics Society}, year = {2000}, doi = {10.1111/j.1532-5415.2000.tb04718.x}, pmid = {10855596}, url = {https://doi.org/10.1111/j.1532-5415.2000.tb04718.x} } @article{paranjpe2021-34658838, author = {Paranjpe, M. D. and Belonwu, S. and Wang, J. K. and Oskotsky, T. and Gupta, A. and Taubes, A. and Zalocusky, K. A. and Paranjpe, I. and others}, title = {{Sex-Specific Cross Tissue Meta-Analysis Identifies Immune Dysregulation in Women With Alzheimer's Disease}}, journal = {Frontiers in aging neuroscience}, year = {2021}, doi = {10.3389/fnagi.2021.735611}, pmid = {34658838}, url = {https://doi.org/10.3389/fnagi.2021.735611} } @article{mclachlan2024-c829b099, author = {McLachlan, M. and Bettcher, B. and McVea, A. and DiFillipo, A. and Zammit, M. and LeMerise, L. and Rouanet, J. and Price, J. and others}, title = {{The striatum is an early, accurate indicator of amyloid burden using [11C]PiB in Down syndrome: comparison of two radiotracers}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1101/2024.12.04.24318526}, url = {https://doi.org/10.1101/2024.12.04.24318526} } @article{hyman2012-22265587, author = {Hyman, B. T. and Phelps, C. H. and Beach, T. G. and Bigio, E. H. and Cairns, N. J. and Carrillo, M. C. and Dickson, D. W. and Duyckaerts, C. and others}, title = {{National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2012}, doi = {10.1016/j.jalz.2011.10.007}, pmid = {22265587}, url = {https://doi.org/10.1016/j.jalz.2011.10.007} } @article{rauch2020-32296178, author = {Rauch, J. N. and Luna, G. and Guzman, E. and Audouard, M. and Challis, C. and Sibih, Y. E. and Leshuk, C. and Hernandez, I. and others}, title = {{LRP1 is a master regulator of tau uptake and spread}}, journal = {Nature}, year = {2020}, doi = {10.1038/s41586-020-2156-5}, pmid = {32296178}, url = {https://doi.org/10.1038/s41586-020-2156-5} } @article{huijbers2015-25678559, author = {Huijbers, W. and Mormino, E. C. and Schultz, A. P. and Wigman, S. and Ward, A. M. and Larvie, M. and Amariglio, R. E. and Marshall, G. A. and others}, title = {{Amyloid-β deposition in mild cognitive impairment is associated with increased hippocampal activity, atrophy and clinical progression}}, journal = {Brain : a journal of neurology}, year = {2015}, doi = {10.1093/brain/awv007}, pmid = {25678559}, url = {https://doi.org/10.1093/brain/awv007} } @article{krasemann2017-28930663, author = {Krasemann, S. and Madore, C. and Cialic, R. and Baufeld, C. and Calcagno, N. and El Fatimy, R. and Beckers, L. and O'Loughlin, E. and others}, title = {{The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases}}, journal = {Immunity}, year = {2017}, doi = {10.1016/j.immuni.2017.08.008}, pmid = {28930663}, url = {https://doi.org/10.1016/j.immuni.2017.08.008} } @article{dickerson2007-18056553, author = {Dickerson, B. C. and Sperling, R. A. and Hyman, B. T. and Albert, M. S. and Blacker, D.}, title = {{Clinical prediction of Alzheimer disease dementia across the spectrum of mild cognitive impairment}}, journal = {Archives of general psychiatry}, year = {2007}, doi = {10.1001/archpsyc.64.12.1443}, pmid = {18056553}, url = {https://doi.org/10.1001/archpsyc.64.12.1443} } @article{fotiadis2016-27180034, author = {Fotiadis, P. and van Rooden, S. and van der Grond, J. and Schultz, A. and Martinez-Ramirez, S. and Auriel, E. and Reijmer, Y. and van Opstal, A. M. and others}, title = {{Cortical atrophy in patients with cerebral amyloid angiopathy: a case-control study}}, journal = {The Lancet. Neurology}, year = {2016}, doi = {10.1016/s1474-4422(16)30030-8}, pmid = {27180034}, url = {https://doi.org/10.1016/s1474-4422(16)30030-8} } @article{zhong2024-39106873, author = {Zhong, J. and Zhang, Y. and Zhu, K. and Li, R. and Zhou, X. and Yao, P. and Franco, O. H. and Manson, J. E. and others}, title = {{Associations of social determinants of health with life expectancy and future health risks among individuals with type 2 diabetes: two nationwide cohort studies in the UK and USA}}, journal = {The lancet. Healthy longevity}, year = {2024}, doi = {10.1016/s2666-7568(24)00116-8}, pmid = {39106873}, url = {https://doi.org/10.1016/s2666-7568(24)00116-8} } @article{mcgrath2022-35584926, author = {McGrath, E. R. and Beiser, A. S. and O'Donnell, A. and Himali, J. J. and Pase, M. P. and Satizabal, C. L. and Seshadri, S.}, title = {{Determining Vascular Risk Factors for Dementia and Dementia Risk Prediction Across Mid- to Later Life: The Framingham Heart Study}}, journal = {Neurology}, year = {2022}, doi = {10.1212/wnl.0000000000200521}, pmid = {35584926}, url = {https://doi.org/10.1212/wnl.0000000000200521} } @article{gottesman2020-31860001, author = {Gottesman, R. F. and Mosley, T. H. and Knopman, D. S. and Hao, Q. and Wong, D. and Wagenknecht, L. E. and Hughes, T. M. and Qiao, Y. and others}, title = {{Association of Intracranial Atherosclerotic Disease With Brain β-Amyloid Deposition: Secondary Analysis of the ARIC Study}}, journal = {JAMA neurology}, year = {2020}, doi = {10.1001/jamaneurol.2019.4339}, pmid = {31860001}, url = {https://doi.org/10.1001/jamaneurol.2019.4339} } @article{serranopozo2013-23656989, author = {Serrano-Pozo, A. and Muzikansky, A. and Gómez-Isla, T. and Growdon, J. H. and Betensky, R. A. and Frosch, M. P. and Hyman, B. T.}, title = {{Differential relationships of reactive astrocytes and microglia to fibrillar amyloid deposits in Alzheimer disease}}, journal = {Journal of neuropathology and experimental neurology}, year = {2013}, doi = {10.1097/nen.0b013e3182933788}, pmid = {23656989}, url = {https://doi.org/10.1097/nen.0b013e3182933788} } @article{delaney2025-39899291, author = {Delaney, Scott and Stegmuller, Angela R. and Mork, Daniel and Mock, Lauren and Bell, Michelle Lee and Gill, Thomas M. and Braun, Danielle and Zanobetti, Antonella}, title = {{Extreme Heat and Hospitalization Among Older Persons With Alzheimer Disease and Related Dementias}}, journal = {JAMA Internal Medicine}, year = {2025}, doi = {10.1001/jamainternmed.2024.7719}, pmid = {39899291}, url = {https://doi.org/10.1001/jamainternmed.2024.7719} } @article{grill2026-41910973, author = {Grill, Joshua D. and RAMAN, REMA and Wang, Shunran and Ernstrom, Karin B. and Andrews, Patricia and Appleby, Brian Stephen and Bhangu, Jaspreet S. and Dhadda, Shobha and others}, title = {{Amyloid Imaging and APOE Genotype Disclosure and Short-Term Psychological Distress}}, journal = {JAMA Network Open}, year = {2026}, doi = {10.1001/jamanetworkopen.2026.3845}, pmid = {41910973}, url = {https://doi.org/10.1001/jamanetworkopen.2026.3845} } @article{liu2025-40163358, author = {Liu, Michael and Marinacci, Lucas and Maddox, Karen E. Joynt and Wadhera, Rishi K.}, title = {{Cardiovascular Health Among Rural and Urban US Adults—Healthcare, Lifestyle, and Social Factors}}, journal = {JAMA Cardiology}, year = {2025}, doi = {10.1001/jamacardio.2025.0538}, pmid = {40163358}, url = {https://doi.org/10.1001/jamacardio.2025.0538} } @article{mormino2016-27548655, author = {Mormino, E. C. and Papp, K. V. and Rentz, D. M. and Schultz, A. P. and LaPoint, M. and Amariglio, R. and Hanseeuw, B. and Marshall, G. A. and others}, title = {{Heterogeneity in Suspected Non-Alzheimer Disease Pathophysiology Among Clinically Normal Older Individuals}}, journal = {JAMA neurology}, year = {2016}, doi = {10.1001/jamaneurol.2016.2237}, pmid = {27548655}, url = {https://doi.org/10.1001/jamaneurol.2016.2237} } @article{schultz2024-39074479, author = {Schultz, S. A. and Liu, L. and Schultz, A. P. and Fitzpatrick, C. D. and Levin, R. and Bellier, J. P. and Shirzadi, Z. and Joseph-Mathurin, N. and others}, title = {{γ-Secretase activity, clinical features, and biomarkers of autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analysis of the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS)}}, journal = {The Lancet. Neurology}, year = {2024}, doi = {10.1016/s1474-4422(24)00236-9}, pmid = {39074479}, url = {https://doi.org/10.1016/s1474-4422(24)00236-9} } @article{shankar2008-18568035, author = {Shankar, Ganesh M. and Li, Shaomin and Mehta, Tapan and García-Muñoz, Amaya and Shepardson, Nina E. and Smith, Imelda M. and Brett, Francesca M. and Farrell, Michael Anthony and Rowan, Michael J. and Lemere, Cynthia Ann and Regan, Ciaran M. and Walsh, Dominic M. and Sabatini, Bernardo Luis and Selkoe, Dennis J.}, title = {{Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory}}, journal = {Nature Medicine}, year = {2008}, doi = {10.1038/nm1782}, pmid = {18568035}, url = {https://doi.org/10.1038/nm1782} } @article{study2020-32161412, author = {{the Dominantly Inherited Alzheimer Network} and Barthélemy, Nicolas R. and Li, Yan and Joseph‐Mathurin, Nelly and Gordon, Brian Andrew and Hassenstab, Jason J. and Benzinger, Tammie L.S. and Buckles, Virginia and Fagan, Anne M. and Perrin, Richard J. and Goate, Alison and Morris, John C. and Karch, Celeste M M. and Xiong, Chengjie and Allegri, Ricardo and Méndez, Patricio Chrem and Berman, Sarah B. and Ikeuchi, Takeshi and Mori, Hiroshi and Shimada, Hiroyuki and Shoji, Mikio and Suzuki, Kazushi and Noble, James McC. and Farlow, Martin Rhys and Chhatwal, Jasmeer P. and Graff‐Radford, Neill R. and Salloway, Stephen and Schofield, Peter R. and Masters, Colin Louis and Martins, Ralph Nigel and O’Connor, Antoinette and Fox, Nick C. and Levin, Johannes and Jucker, Mathias and Gabelle, Audrey and Lehmann, Sylvain and Sato, Chihiro and Bateman, Randall John and Bateman, Randall J. and McDade, Eric}, title = {{A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease}}, journal = {Nature Medicine}, year = {2020}, doi = {10.1038/s41591-020-0781-z}, pmid = {32161412}, url = {https://doi.org/10.1038/s41591-020-0781-z} } @article{taddei2023-37812432, author = {Taddei, R. N. and Perbet, R. and Mate de Gerando, A. and Wiedmer, A. E. and Sanchez-Mico, M. and Connors Stewart, T. and Gaona, A. and Melloni, A. and others}, title = {{Tau Oligomer-Containing Synapse Elimination by Microglia and Astrocytes in Alzheimer Disease}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.3530}, pmid = {37812432}, url = {https://doi.org/10.1001/jamaneurol.2023.3530} } @article{fagan2021-34302786, author = {Fagan, A. M. and Henson, R. L. and Li, Y. and Boerwinkle, A. H. and Xiong, C. and Bateman, R. J. and Goate, A. and Ances, B. M. and others}, title = {{Comparison of CSF biomarkers in Down syndrome and autosomal dominant Alzheimer's disease: a cross-sectional study}}, journal = {The Lancet. Neurology}, year = {2021}, doi = {10.1016/s1474-4422(21)00139-3}, pmid = {34302786}, url = {https://doi.org/10.1016/s1474-4422(21)00139-3} } @article{kivisakk2022-35800899, author = {Kivisäkk, P. and Magdamo, C. and Trombetta, B. A. and Noori, A. and Kuo, Y. K. E. and Chibnik, L. B. and Carlyle, B. C. and Serrano-Pozo, A. and others}, title = {{Plasma biomarkers for prognosis of cognitive decline in patients with mild cognitive impairment}}, journal = {Brain communications}, year = {2022}, doi = {10.1093/braincomms/fcac155}, pmid = {35800899}, url = {https://doi.org/10.1093/braincomms/fcac155} } @article{sperling2012-22305802, author = {Sperling, R. and Salloway, S. and Brooks, D. J. and Tampieri, D. and Barakos, J. and Fox, N. C. and Raskind, M. and Sabbagh, M. and others}, title = {{Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis}}, journal = {The Lancet. Neurology}, year = {2012}, doi = {10.1016/s1474-4422(12)70015-7}, pmid = {22305802}, url = {https://doi.org/10.1016/s1474-4422(12)70015-7} } @article{roberts2012-22498844, author = {Roberts, J. S. and Chen, C. A. and Uhlmann, W. R. and Green, R. C.}, title = {{Effectiveness of a condensed protocol for disclosing APOE genotype and providing risk education for Alzheimer disease}}, journal = {Genetics in medicine : official journal of the American College of Medical Genetics}, year = {2012}, doi = {10.1038/gim.2012.37}, pmid = {22498844}, url = {https://doi.org/10.1038/gim.2012.37} } @article{liu2025-40876538, author = {Liu, X. and Sacks, F. M. and Beck, T. and Tangney, C. C. and Willett, W. C. and Yassine, H. and Dhana, K. and Aggarwal, N. T. and others}, title = {{Apolipoprotein E ε4-dependent associations between carotenoids and cognitive decline: Findings from the MIND (Mediterranean-DASH Intervention for Neurodegenerative delay) randomized controlled trial}}, journal = {The American journal of clinical nutrition}, year = {2025}, doi = {10.1016/j.ajcnut.2025.08.012}, pmid = {40876538}, url = {https://doi.org/10.1016/j.ajcnut.2025.08.012} } @article{crary2014-25348064, author = {Crary, J. F. and Trojanowski, J. Q. and Schneider, J. A. and Abisambra, J. F. and Abner, E. L. and Alafuzoff, I. and Arnold, S. E. and Attems, J. and others}, title = {{Primary age-related tauopathy (PART): a common pathology associated with human aging}}, journal = {Acta neuropathologica}, year = {2014}, doi = {10.1007/s00401-014-1349-0}, pmid = {25348064}, url = {https://doi.org/10.1007/s00401-014-1349-0} } @article{buell2010-19940273, author = {Buell, J. S. and Dawson-Hughes, B. and Scott, T. M. and Weiner, D. E. and Dallal, G. E. and Qui, W. Q. and Bergethon, P. and Rosenberg, I. H. and others}, title = {{25-Hydroxyvitamin D, dementia, and cerebrovascular pathology in elders receiving home services}}, journal = {Neurology}, year = {2010}, doi = {10.1212/wnl.0b013e3181beecb7}, pmid = {19940273}, url = {https://doi.org/10.1212/wnl.0b013e3181beecb7} } @article{katzmarzyk2022-33782046, author = {Katzmarzyk, P. T. and Friedenreich, C. and Shiroma, E. J. and Lee, I. M.}, title = {{Physical inactivity and non-communicable disease burden in low-income, middle-income and high-income countries}}, journal = {British journal of sports medicine}, year = {2022}, doi = {10.1136/bjsports-2020-103640}, pmid = {33782046}, url = {https://doi.org/10.1136/bjsports-2020-103640} } @article{buckley2017-28973551, author = {Buckley, R. F. and Hanseeuw, B. and Schultz, A. P. and Vannini, P. and Aghjayan, S. L. and Properzi, M. J. and Jackson, J. D. and Mormino, E. C. and others}, title = {{Region-Specific Association of Subjective Cognitive Decline With Tauopathy Independent of Global β-Amyloid Burden}}, journal = {JAMA neurology}, year = {2017}, doi = {10.1001/jamaneurol.2017.2216}, pmid = {28973551}, url = {https://doi.org/10.1001/jamaneurol.2017.2216} } @article{greenberg2009-19161908, author = {Greenberg, S. M. and Vernooij, M. W. and Cordonnier, C. and Viswanathan, A. and Al-Shahi Salman, R. and Warach, S. and Launer, L. J. and Van Buchem, M. A. and others}, title = {{Cerebral microbleeds: a guide to detection and interpretation}}, journal = {The Lancet. Neurology}, year = {2009}, doi = {10.1016/s1474-4422(09)70013-4}, pmid = {19161908}, url = {https://doi.org/10.1016/s1474-4422(09)70013-4} } @article{benner2002-12132975, author = {Benner, J. S. and Glynn, R. J. and Mogun, H. and Neumann, P. J. and Weinstein, M. C. and Avorn, J.}, title = {{Long-term persistence in use of statin therapy in elderly patients}}, journal = {JAMA}, year = {2002}, doi = {10.1001/jama.288.4.455}, pmid = {12132975}, url = {https://doi.org/10.1001/jama.288.4.455} } @article{akoudad2016-27271785, author = {Akoudad, S. and Wolters, F. J. and Viswanathan, A. and de Bruijn, R. F. and van der Lugt, A. and Hofman, A. and Koudstaal, P. J. and Ikram, M. A. and others}, title = {{Association of Cerebral Microbleeds With Cognitive Decline and Dementia}}, journal = {JAMA neurology}, year = {2016}, doi = {10.1001/jamaneurol.2016.1017}, pmid = {27271785}, url = {https://doi.org/10.1001/jamaneurol.2016.1017} } @article{sekhon2021-33308615, author = {Sekhon, H. and Sekhon, K. and Launay, C. and Afililo, M. and Innocente, N. and Vahia, I. and Rej, S. and Beauchet, O.}, title = {{Telemedicine and the rural dementia population: A systematic review}}, journal = {Maturitas}, year = {2021}, doi = {10.1016/j.maturitas.2020.09.001}, pmid = {33308615}, url = {https://doi.org/10.1016/j.maturitas.2020.09.001} } @article{morris2015-26086182, author = {Morris, M. C. and Tangney, C. C. and Wang, Y. and Sacks, F. M. and Barnes, L. L. and Bennett, D. A. and Aggarwal, N. T.}, title = {{MIND diet slows cognitive decline with aging}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2015}, doi = {10.1016/j.jalz.2015.04.011}, pmid = {26086182}, url = {https://doi.org/10.1016/j.jalz.2015.04.011} } @article{melamed2019-30643298, author = {Melamed, Z. and López-Erauskin, J. and Baughn, M. W. and Zhang, O. and Drenner, K. and Sun, Y. and Freyermuth, F. and McMahon, M. A. and others}, title = {{Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration}}, journal = {Nature neuroscience}, year = {2019}, doi = {10.1038/s41593-018-0293-z}, pmid = {30643298}, url = {https://doi.org/10.1038/s41593-018-0293-z} } @article{ghetti2015-25556536, author = {Ghetti, B. and Oblak, A. L. and Boeve, B. F. and Johnson, K. A. and Dickerson, B. C. and Goedert, M.}, title = {{Invited review: Frontotemporal dementia caused by microtubule-associated protein tau gene (MAPT) mutations: a chameleon for neuropathology and neuroimaging}}, journal = {Neuropathology and applied neurobiology}, year = {2015}, doi = {10.1111/nan.12213}, pmid = {25556536}, url = {https://doi.org/10.1111/nan.12213} } @article{spasov2019-30654174, author = {Spasov, S. and Passamonti, L. and Duggento, A. and Liò, P. and Toschi, N. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{A parameter-efficient deep learning approach to predict conversion from mild cognitive impairment to Alzheimer's disease}}, journal = {NeuroImage}, year = {2019}, doi = {10.1016/j.neuroimage.2019.01.031}, pmid = {30654174}, url = {https://doi.org/10.1016/j.neuroimage.2019.01.031} } @article{meghdadi2021-33544703, author = {Meghdadi, A. H. and Stevanović Karić, M. and McConnell, M. and Rupp, G. and Richard, C. and Hamilton, J. and Salat, D. and Berka, C.}, title = {{Resting state EEG biomarkers of cognitive decline associated with Alzheimer's disease and mild cognitive impairment}}, journal = {PloS one}, year = {2021}, doi = {10.1371/journal.pone.0244180}, pmid = {33544703}, url = {https://doi.org/10.1371/journal.pone.0244180} } @article{li2020-34179863, author = {Li, P. and Gao, L. and Gaba, A. and Yu, L. and Cui, L. and Fan, W. and Lim, A. S. P. and Bennett, D. A. and others}, title = {{Circadian disturbances in Alzheimer's disease progression: a prospective observational cohort study of community-based older adults}}, journal = {The lancet. Healthy longevity}, year = {2020}, doi = {10.1016/s2666-7568(20)30015-5}, pmid = {34179863}, url = {https://doi.org/10.1016/s2666-7568(20)30015-5} } @article{rawlings2018-30045960, author = {Rawlings, A. M. and Juraschek, S. P. and Heiss, G. and Hughes, T. and Meyer, M. L. and Selvin, E. and Sharrett, A. R. and Windham, B. G. and others}, title = {{Association of orthostatic hypotension with incident dementia, stroke, and cognitive decline}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000006027}, pmid = {30045960}, url = {https://doi.org/10.1212/wnl.0000000000006027} } @article{ulsa2022-34558609, author = {Ulsa, M. C. and Xi, Z. and Li, P. and Gaba, A. and Wong, P. M. and Saxena, R. and Scheer, F. A. J. L. and Rutter, M. and others}, title = {{Association of Poor Sleep Burden in Middle Age and Older Adults With Risk for Delirium During Hospitalization}}, journal = {The journals of gerontology. Series A, Biological sciences and medical sciences}, year = {2022}, doi = {10.1093/gerona/glab272}, pmid = {34558609}, url = {https://doi.org/10.1093/gerona/glab272} } @article{ramoscejudo2021-34916927, author = {Ramos-Cejudo, J. and Johnson, A. D. and Beiser, A. and Seshadri, S. and Salinas, J. and Berger, J. S. and Fillmore, N. R. and Do, N. and others}, title = {{The Neutrophil to Lymphocyte Ratio Is Associated With the Risk of Subsequent Dementia in the Framingham Heart Study}}, journal = {Frontiers in aging neuroscience}, year = {2021}, doi = {10.3389/fnagi.2021.773984}, pmid = {34916927}, url = {https://doi.org/10.3389/fnagi.2021.773984} } @article{mormino2017-28253478, author = {Mormino, E. C. and Papp, K. V. and Rentz, D. M. and Donohue, M. C. and Amariglio, R. and Quiroz, Y. T. and Chhatwal, J. and Marshall, G. A. and others}, title = {{Early and late change on the preclinical Alzheimer's cognitive composite in clinically normal older individuals with elevated amyloid β}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2017}, doi = {10.1016/j.jalz.2017.01.018}, pmid = {28253478}, url = {https://doi.org/10.1016/j.jalz.2017.01.018} } @article{dehavenon2023-37218590, author = {de Havenon, Adam and Parasuram, Nethra R. and Crawford, Anna L. and Mazurek, Mercy H. and Chavva, Isha R. and Yadlapalli, Vineetha and Iglesias, Juan Eugenio and Rosen, Matthew Scott and others}, title = {{Identification of White Matter Hyperintensities in Routine Emergency Department Visits Using Portable Bedside Magnetic Resonance Imaging}}, journal = {Journal of the American Heart Association}, year = {2023}, doi = {10.1161/jaha.122.029242}, pmid = {37218590}, url = {https://doi.org/10.1161/jaha.122.029242} } @article{wang2025-40009382, author = {Wang, Anqi and Van Blarigan, Erin Lynn and Cheng, Iona C. and Chan, June M. and Wan, Peggy C. and Park, Song‐Yi and Xiong, Wei and Hamilton, Ann S. and others}, title = {{Race and Ethnicity, Lifestyle, Diet, and Survival in Patients With Prostate Cancer}}, journal = {JAMA Network Open}, year = {2025}, doi = {10.1001/jamanetworkopen.2024.60785}, pmid = {40009382}, url = {https://doi.org/10.1001/jamanetworkopen.2024.60785} } @article{wang2025-40938598, author = {Wang, Jinqi and Jiao, Danyang and Zhao, Xiaoyu and Tian, Yixing and Li, Haibin and Li, Xia and Sheng, Chen and Tao, Lixin and others}, title = {{Childhood Loneliness and Cognitive Decline and Dementia Risk in Middle-Aged and Older Adults}}, journal = {JAMA Network Open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.31493}, pmid = {40938598}, url = {https://doi.org/10.1001/jamanetworkopen.2025.31493} } @article{nelson2012-22487856, author = {Nelson, Peter T. and Alafuzoff, Irina I. and Bigio, Eileen H. and Bouras, Constantin and Braak, Heiko and Cairns, Nigel J. and Castellani, Rudolph J. and Crain, Barbara J. and others}, title = {{Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature}}, journal = {Journal of Neuropathology \& Experimental Neurology}, year = {2012}, doi = {10.1097/nen.0b013e31825018f7}, pmid = {22487856}, url = {https://doi.org/10.1097/nen.0b013e31825018f7} } @article{fischl2002-11832223, author = {Fischl, Bruce R. and Salat, David H. and Busa, Evelina and Albert, Marilyn and Dieterich, Megan and Haselgrove, Christian and van der Kouwe, Andre J. W. and Killiany, Ronald and others}, title = {{Whole Brain Segmentation}}, journal = {Neuron}, year = {2002}, doi = {10.1016/s0896-6273(02)00569-x}, pmid = {11832223}, url = {https://doi.org/10.1016/s0896-6273(02)00569-x} } @article{butovsky2013-24316888, author = {Butovsky, Oleg and Jedrychowski, Mark P. and Moore, Craig Stephen and Cialic, Ron and Lanser, Amanda J. and Gabriely, Galina and Koeglsperger, Thomas and Dake, Ben and Wu, Pauline M. and Doykan, Camille E. and Fanek, Zain and Liu, Liping and Chen, Zhuoxun and Rothstein, Jeffrey D. and Ransohoff, Richard M. and Gygi, Steven P. and Antel, Jack Perry and Weiner, Howard L.}, title = {{Identification of a unique TGF-β–dependent molecular and functional signature in microglia}}, journal = {Nature Neuroscience}, year = {2013}, doi = {10.1038/nn.3599}, pmid = {24316888}, url = {https://doi.org/10.1038/nn.3599} } @article{winblad2016-26987701, author = {Winblad, Bengt G. and Amouyel, Philippe and Andrieu, Sandrine and Ballard, Clive G. and Brayne, Carol and Brodaty, Henry and Cedazo-Mínguez, Ángel and Dubois, Bruno and Edvardsson, David and Feldman, Howard and Fratiglioni, Laura and Frisoni, Giovanni Battista and Gauthier, Serge G. and Georges, Jean and Graff, Caroline and Iqbal, Khalid and Jessen, Frank and Johansson, Gunilla and Jönsson, Linus and Kivipelto, Miia and Knapp, Martin Richard John and Mangialasche, Francesca and Melis, René J. F. and Nordberg, Agneta K. and Rikkert, Marcel G. M. Olde and Qiu, Chengxuan and Sakmar, Thomas P. and Scheltens, Philip and Schneider, Lon S. S. and Sperling, Reisa Anne and Tjernberg, Lars O. and Waldemar, Gunhild and Wimo, Anders and Zetterberg, Henrik}, title = {{Defeating Alzheimer's disease and other dementias: a priority for European science and society}}, journal = {The Lancet Neurology}, year = {2016}, doi = {10.1016/s1474-4422(16)00062-4}, pmid = {26987701}, url = {https://doi.org/10.1016/s1474-4422(16)00062-4} } @article{jessen2020-31958406, author = {Jessen, Frank and Amariglio, Rebecca England and Buckley, Rachel F. and van der Flier, Wiesje M. and Han, Ying and Molinuevo, José Luís and Rabin, Laura A. and Rentz, Dorene M. and Rodríguez‐Gómez, Octavio and Saykin, Andrew J. and Sikkes, Sietske A.M. and Smart, Colette M. and Wolfsgruber, Steffen and Wagner, Michael}, title = {{The characterisation of subjective cognitive decline}}, journal = {The Lancet Neurology}, year = {2020}, doi = {10.1016/s1474-4422(19)30368-0}, pmid = {31958406}, url = {https://doi.org/10.1016/s1474-4422(19)30368-0} } @article{browne2025-39984462, author = {Browne, D. F. and Smirnov, D. S. and Coughlin, D. G. and Peng, I. and Standke, H. G. and Kim, Y. and Pizzo, D. P. and Unapanta, A. and Andreasson, T. and Hiniker, A. and Kraus, A.}, title = {{Early Alzheimer's Disease with frequent neuritic plaques harbors neocortical tau seeds distinct from primary age-related tauopathy}}, journal = {Nature Communications}, year = {2025}, doi = {10.1038/s41467-025-56469-7}, pmid = {39984462}, url = {https://doi.org/10.1038/s41467-025-56469-7} } @article{yu2017-28108637, author = {Yu, L. and Lutz, M. W. and Wilson, R. S. and Burns, D. K. and Roses, A. D. and Saunders, A. M. and Gaiteri, C. and De Jager, P. L. and others}, title = {{TOMM40'523 variant and cognitive decline in older persons with APOE ε3/3 genotype}}, journal = {Neurology}, year = {2017}, doi = {10.1212/wnl.0000000000003614}, pmid = {28108637}, url = {https://doi.org/10.1212/wnl.0000000000003614} } @article{seto2024-38884955, author = {Seto, M. and Hohman, T. J. and Mormino, E. C. and Papp, K. V. and Amariglio, R. E. and Rentz, D. M. and Johnson, K. A. and Schultz, A. P. and others}, title = {{Parental History of Memory Impairment and β-Amyloid in Cognitively Unimpaired Older Adults}}, journal = {JAMA neurology}, year = {2024}, doi = {10.1001/jamaneurol.2024.1763}, pmid = {38884955}, url = {https://doi.org/10.1001/jamaneurol.2024.1763} } @article{rost2022-35420911, author = {Rost, N. S. and Brodtmann, A. and Pase, M. P. and van Veluw, S. J. and Biffi, A. and Duering, M. and Hinman, J. D. and Dichgans, M.}, title = {{Post-Stroke Cognitive Impairment and Dementia}}, journal = {Circulation research}, year = {2022}, doi = {10.1161/circresaha.122.319951}, pmid = {35420911}, url = {https://doi.org/10.1161/circresaha.122.319951} } @article{kivipelto2020-32627328, author = {Kivipelto, M. and Mangialasche, F. and Snyder, H. M. and Allegri, R. and Andrieu, S. and Arai, H. and Baker, L. and Belleville, S. and others}, title = {{World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2020}, doi = {10.1002/alz.12123}, pmid = {32627328}, url = {https://doi.org/10.1002/alz.12123} } @article{reiman2020-32015339, author = {Reiman, E. M. and Arboleda-Velasquez, J. F. and Quiroz, Y. T. and Huentelman, M. J. and Beach, T. G. and Caselli, R. J. and Chen, Y. and Su, Y. and others}, title = {{Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study}}, journal = {Nature communications}, year = {2020}, doi = {10.1038/s41467-019-14279-8}, pmid = {32015339}, url = {https://doi.org/10.1038/s41467-019-14279-8} } @article{shah2016-27751558, author = {Shah, H. and Albanese, E. and Duggan, C. and Rudan, I. and Langa, K. M. and Carrillo, M. C. and Chan, K. Y. and Joanette, Y. and others}, title = {{Research priorities to reduce the global burden of dementia by 2025}}, journal = {The Lancet. Neurology}, year = {2016}, doi = {10.1016/s1474-4422(16)30235-6}, pmid = {27751558}, url = {https://doi.org/10.1016/s1474-4422(16)30235-6} } @article{orkaby2017-28954880, author = {Orkaby, A. R. and Cho, K. and Cormack, J. and Gagnon, D. R. and Driver, J. A.}, title = {{Metformin vs sulfonylurea use and risk of dementia in US veterans aged ≥65 years with diabetes}}, journal = {Neurology}, year = {2017}, doi = {10.1212/wnl.0000000000004586}, pmid = {28954880}, url = {https://doi.org/10.1212/wnl.0000000000004586} } @article{krivanek2021-33935078, author = {Krivanek, T. J. and Gale, S. A. and McFeeley, B. M. and Nicastri, C. M. and Daffner, K. R.}, title = {{Promoting Successful Cognitive Aging: A Ten-Year Update}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2021}, doi = {10.3233/jad-201462}, pmid = {33935078}, url = {https://doi.org/10.3233/jad-201462} } @article{mckhann2011-21514250, author = {McKhann, G. M. and Knopman, D. S. and Chertkow, H. and Hyman, B. T. and Jack, C. R. and Kawas, C. H. and Klunk, W. E. and Koroshetz, W. J. and others}, title = {{The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2011}, doi = {10.1016/j.jalz.2011.03.005}, pmid = {21514250}, url = {https://doi.org/10.1016/j.jalz.2011.03.005} } @article{johnson2016-26505746, author = {Johnson, K. A. and Schultz, A. and Betensky, R. A. and Becker, J. A. and Sepulcre, J. and Rentz, D. and Mormino, E. and Chhatwal, J. and others}, title = {{Tau positron emission tomographic imaging in aging and early Alzheimer disease}}, journal = {Annals of neurology}, year = {2016}, doi = {10.1002/ana.24546}, pmid = {26505746}, url = {https://doi.org/10.1002/ana.24546} } @article{mckee2016-26667418, author = {McKee, A. C. and Cairns, N. J. and Dickson, D. W. and Folkerth, R. D. and Keene, C. D. and Litvan, I. and Perl, D. P. and Stein, T. D. and others}, title = {{The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy}}, journal = {Acta neuropathologica}, year = {2016}, doi = {10.1007/s00401-015-1515-z}, pmid = {26667418}, url = {https://doi.org/10.1007/s00401-015-1515-z} } @article{mollenhauer2011-21317042, author = {Mollenhauer, B. and Locascio, J. J. and Schulz-Schaeffer, W. and Sixel-Döring, F. and Trenkwalder, C. and Schlossmacher, M. G.}, title = {{α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study}}, journal = {The Lancet. Neurology}, year = {2011}, doi = {10.1016/s1474-4422(11)70014-x}, pmid = {21317042}, url = {https://doi.org/10.1016/s1474-4422(11)70014-x} } @article{mayeux1998-9468467, author = {Mayeux, R. and Saunders, A. M. and Shea, S. and Mirra, S. and Evans, D. and Roses, A. D. and Hyman, B. T. and Crain, B. and others}, title = {{Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease. Alzheimer's Disease Centers Consortium on Apolipoprotein E and Alzheimer's Disease}}, journal = {The New England journal of medicine}, year = {1998}, doi = {10.1056/nejm199802193380804}, pmid = {9468467}, url = {https://doi.org/10.1056/nejm199802193380804} } @article{dubois2024-39483064, author = {Dubois, B. and Villain, N. and Schneider, L. and Fox, N. and Campbell, N. and Galasko, D. and Kivipelto, M. and Jessen, F. and others}, title = {{Alzheimer Disease as a Clinical-Biological Construct-An International Working Group Recommendation}}, journal = {JAMA neurology}, year = {2024}, doi = {10.1001/jamaneurol.2024.3770}, pmid = {39483064}, url = {https://doi.org/10.1001/jamaneurol.2024.3770} } @article{smith2008-18195145, author = {Smith, E. E. and Egorova, S. and Blacker, D. and Killiany, R. J. and Muzikansky, A. and Dickerson, B. C. and Tanzi, R. E. and Albert, M. S. and others}, title = {{Magnetic resonance imaging white matter hyperintensities and brain volume in the prediction of mild cognitive impairment and dementia}}, journal = {Archives of neurology}, year = {2008}, doi = {10.1001/archneurol.2007.23}, pmid = {18195145}, url = {https://doi.org/10.1001/archneurol.2007.23} } @article{coughlan2023-37010830, author = {Coughlan, G. T. and Betthauser, T. J. and Boyle, R. and Koscik, R. L. and Klinger, H. M. and Chibnik, L. B. and Jonaitis, E. M. and Yau, W. W. and others}, title = {{Association of Age at Menopause and Hormone Therapy Use With Tau and β-Amyloid Positron Emission Tomography}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.0455}, pmid = {37010830}, url = {https://doi.org/10.1001/jamaneurol.2023.0455} } @article{gonzalezgomez2024-39136296, author = {Gonzalez-Gomez, R. and Legaz, A. and Moguilner, S. and Cruzat, J. and Hernández, H. and Baez, S. and Cocchi, R. and Coronel-Olivero, C. and others}, title = {{Educational disparities in brain health and dementia across Latin America and the United States}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.14085}, pmid = {39136296}, url = {https://doi.org/10.1002/alz.14085} } @article{lu2014-24670762, author = {Lu, T. and Aron, L. and Zullo, J. and Pan, Y. and Kim, H. and Chen, Y. and Yang, T. H. and Kim, H. M. and others}, title = {{REST and stress resistance in ageing and Alzheimer's disease}}, journal = {Nature}, year = {2014}, doi = {10.1038/nature13163}, pmid = {24670762}, url = {https://doi.org/10.1038/nature13163} } @article{crutch2017-28259709, author = {Crutch, S. J. and Schott, J. M. and Rabinovici, G. D. and Murray, M. and Snowden, J. S. and van der Flier, W. M. and Dickerson, B. C. and Vandenberghe, R. and others}, title = {{Consensus classification of posterior cortical atrophy}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2017}, doi = {10.1016/j.jalz.2017.01.014}, pmid = {28259709}, url = {https://doi.org/10.1016/j.jalz.2017.01.014} } @article{damesquita2021-33911285, author = {Da Mesquita, S. and Papadopoulos, Z. and Dykstra, T. and Brase, L. and Farias, F. G. and Wall, M. and Jiang, H. and Kodira, C. D. and others}, title = {{Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy}}, journal = {Nature}, year = {2021}, doi = {10.1038/s41586-021-03489-0}, pmid = {33911285}, url = {https://doi.org/10.1038/s41586-021-03489-0} } @article{hay2025-41092926, author = {Hay, Simon Iain and Ong, Kanyin Liane and Santomauro, Damian Francesco and Bhoomadevi, A and Aalipour, Mohammad Amin and Aalruz, Hasan and Ababneh, Hazim and Abaraogu, Ukachukwu Okoroafor and others}, title = {{Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023}}, journal = {The Lancet}, year = {2025}, doi = {10.1016/s0140-6736(25)01637-x}, pmid = {41092926}, url = {https://doi.org/10.1016/s0140-6736(25)01637-x} } @article{ruizcanela2025-40854218, author = {Ruiz‐Canela, Miguel and Corella, Dolores and Martínez‐González, Miguel Ángel and Babió, Nancy and Martínéz, J. Alfredo and Forga, Lluís and Alonso‐Gómez, Ángel M. and Wärnberǵ, Julia and others}, title = {{Comparison of an Energy-Reduced Mediterranean Diet and Physical Activity Versus an Ad Libitum Mediterranean Diet in the Prevention of Type 2 Diabetes}}, journal = {Annals of Internal Medicine}, year = {2025}, doi = {10.7326/annals-25-00388}, pmid = {40854218}, url = {https://doi.org/10.7326/annals-25-00388} } @article{cribb2025-39894022, author = {Cribb, Lachlan and Moreno‐Betancur, Margarita and Wu, Zimu and Wolfe, Rory and Pase, Matthew Paul and Ryan, Joanne L.}, title = {{Moving beyond the prevalent exposure design for causal inference in dementia research}}, journal = {The Lancet Healthy Longevity}, year = {2025}, doi = {10.1016/j.lanhl.2024.100675}, pmid = {39894022}, url = {https://doi.org/10.1016/j.lanhl.2024.100675} } @article{xu2025-40394891, author = {Xu, Xiaomeng and Yang, Xinyuan and Zhang, Junfang and Wang, Yan and Selim, Magdy H. and Zheng, Yingting and Shen, Ruinan and Sun, Lipeng and others}, title = {{Choroid plexus free‐water correlates with glymphatic function in Alzheimer's disease}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70239}, pmid = {40394891}, url = {https://doi.org/10.1002/alz.70239} } @article{sachdev2025-40955506, author = {Sachdev, Perminder Singh and Bentvelzen, Adam C. and Kochan, Nicole A. and Jiang, Jiyang and Hosoki, Satoshi and Koncz, Rebecca and Chander, Russell Jude and Saks, Danit and others}, title = {{Revised Diagnostic Criteria for Vascular Cognitive Impairment and Dementia—The VasCog-2-WSO Criteria}}, journal = {JAMA Neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.3242}, pmid = {40955506}, url = {https://doi.org/10.1001/jamaneurol.2025.3242} } @article{desikan2006-16530430, author = {Desikan, Rahul S. and Ségonne, Florent and Fischl, Bruce R. and Quinn, Brian T. and Dickerson, Bradford Clark and Blacker, Deborah and Buckner, Randy Lee and Dale, Anders Martin and others}, title = {{An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest}}, journal = {NeuroImage}, year = {2006}, doi = {10.1016/j.neuroimage.2006.01.021}, pmid = {16530430}, url = {https://doi.org/10.1016/j.neuroimage.2006.01.021} } @article{selkoe2016-27025652, author = {Selkoe, Dennis J. and Hardy, John}, title = {{The amyloid hypothesis of Alzheimer's disease at 25 years}}, journal = {EMBO Molecular Medicine}, year = {2016}, doi = {10.15252/emmm.201606210}, pmid = {27025652}, url = {https://doi.org/10.15252/emmm.201606210} } @article{arriagada1992-1549228, author = {Arriagada, Paulina V. and Growdon, John H. and Hedley‐Whyte, E. Tessa and Hyman, Bradley T.}, title = {{Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease}}, journal = {Neurology}, year = {1992}, doi = {10.1212/wnl.42.3.631}, pmid = {1549228}, url = {https://doi.org/10.1212/wnl.42.3.631} } @article{sano1997-9110909, author = {Sano, Mary and Ernesto, Christopher and Thomas, Ronald G. and Klauber, Melville R. and Schafer, Kimberly A and Grundman, Michael and Woodbury, Peter and Growdon, John H. and Cotman, Carl W. and Pfeiffer, Eric A. and Schneider, Lon S. and Thal, Leon J.}, title = {{A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study}}, journal = {New England Journal of Medicine}, year = {1997}, doi = {10.1056/nejm199704243361704}, pmid = {9110909}, url = {https://doi.org/10.1056/nejm199704243361704} } @article{asai2015-26436904, author = {Asai, Hirohide and Ikezu, Seiko and Tsunoda, Satoshi and Medalla, Maria and Luebke, Jennifer Irene and Haydar, Tarik F. and Wolozin, Benjamin L. and Butovsky, Oleg and Kügler, Sebastian and Ikezu, Tsuneya}, title = {{Depletion of microglia and inhibition of exosome synthesis halt tau propagation}}, journal = {Nature Neuroscience}, year = {2015}, doi = {10.1038/nn.4132}, pmid = {26436904}, url = {https://doi.org/10.1038/nn.4132} } @article{rosenberg2025-41350162, author = {Rosenberg, P. B. and Amjad, H. and Burhanullah, H. and Nowrangi, M. and Vandrey, R. and Pierre, M. J. and Outen, J. D. and Schultz, M. and Marano, C. and Agronin, M. and others}, title = {{A Randomized Controlled Trial of the Safety and Efficacy of Dronabinol for Agitation in Alzheimer's Disease}}, journal = {The American Journal of Geriatric Psychiatry}, year = {2025}, doi = {10.1016/j.jagp.2025.10.011}, pmid = {41350162}, url = {https://doi.org/10.1016/j.jagp.2025.10.011} } @article{han2026-42233272, author = {Han, Hae-Ra and Perrin, Nancy and Yun, Ji-Young and Min, Deborah and Kwon, Simona C and Joo, Jinhui and Cho, Ji-Young and Kim, Sara and others}, title = {{Efficacy of a language-concordant community health worker intervention to improve community-to-clinic linkage for dementia care: results of the randomized trial PLAN}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71541}, pmid = {42233272}, url = {https://doi.org/10.1002/alz.71541} } @article{boerwinkle2023-36517172, author = {Boerwinkle, A. H. and Gordon, B. A. and Wisch, J. and Flores, S. and Henson, R. L. and Butt, O. H. and McKay, N. and Chen, C. D. and others}, title = {{Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study}}, journal = {The Lancet. Neurology}, year = {2023}, doi = {10.1016/s1474-4422(22)00408-2}, pmid = {36517172}, url = {https://doi.org/10.1016/s1474-4422(22)00408-2} } @article{mormino2016-27385740, author = {Mormino, E. C. and Sperling, R. A. and Holmes, A. J. and Buckner, R. L. and De Jager, P. L. and Smoller, J. W. and Sabuncu, M. R. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{Polygenic risk of Alzheimer disease is associated with early- and late-life processes}}, journal = {Neurology}, year = {2016}, doi = {10.1212/wnl.0000000000002922}, pmid = {27385740}, url = {https://doi.org/10.1212/wnl.0000000000002922} } @article{nadkarni2017-27842173, author = {Nadkarni, N. K. and Perera, S. and Snitz, B. E. and Mathis, C. A. and Price, J. and Williamson, J. D. and DeKosky, S. T. and Klunk, W. E. and others}, title = {{Association of Brain Amyloid-β With Slow Gait in Elderly Individuals Without Dementia: Influence of Cognition and Apolipoprotein E ε4 Genotype}}, journal = {JAMA neurology}, year = {2017}, doi = {10.1001/jamaneurol.2016.3474}, pmid = {27842173}, url = {https://doi.org/10.1001/jamaneurol.2016.3474} } @article{woodworth2023-37831492, author = {Woodworth, E. C. and Briskin, E. A. and Plys, E. and Macklin, E. and Tatar, R. G. and Huberty, J. and Vranceanu, A. M.}, title = {{Mindfulness-Based App to Reduce Stress in Caregivers of Persons With Alzheimer Disease and Related Dementias: Protocol for a Single-Blind Feasibility Proof-of-Concept Randomized Controlled Trial}}, journal = {JMIR research protocols}, year = {2023}, doi = {10.2196/50108}, pmid = {37831492}, url = {https://doi.org/10.2196/50108} } @article{schmitt2012-22999782, author = {Schmitt, E. M. and Marcantonio, E. R. and Alsop, D. C. and Jones, R. N. and Rogers, S. O. and Fong, T. G. and Metzger, E. and Inouye, S. K. and others}, title = {{Novel risk markers and long-term outcomes of delirium: the successful aging after elective surgery (SAGES) study design and methods}}, journal = {Journal of the American Medical Directors Association}, year = {2012}, doi = {10.1016/j.jamda.2012.08.004}, pmid = {22999782}, url = {https://doi.org/10.1016/j.jamda.2012.08.004} } @article{wang2023-37450568, author = {Wang, T. and Masedunskas, A. and Willett, W. C. and Fontana, L.}, title = {{Vegetarian and vegan diets: benefits and drawbacks}}, journal = {European heart journal}, year = {2023}, doi = {10.1093/eurheartj/ehad436}, pmid = {37450568}, url = {https://doi.org/10.1093/eurheartj/ehad436} } @article{fagan2014-24598588, author = {Fagan, A. M. and Xiong, C. and Jasielec, M. S. and Bateman, R. J. and Goate, A. M. and Benzinger, T. L. and Ghetti, B. and Martins, R. N. and others}, title = {{Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease}}, journal = {Science translational medicine}, year = {2014}, doi = {10.1126/scitranslmed.3007901}, pmid = {24598588}, url = {https://doi.org/10.1126/scitranslmed.3007901} } @article{quiroz2018-29435558, author = {Quiroz, Y. T. and Sperling, R. A. and Norton, D. J. and Baena, A. and Arboleda-Velasquez, J. F. and Cosio, D. and Schultz, A. and Lapoint, M. and others}, title = {{Association Between Amyloid and Tau Accumulation in Young Adults With Autosomal Dominant Alzheimer Disease}}, journal = {JAMA neurology}, year = {2018}, doi = {10.1001/jamaneurol.2017.4907}, pmid = {29435558}, url = {https://doi.org/10.1001/jamaneurol.2017.4907} } @article{lo2012-22972646, author = {Lo, R. Y. and Jagust, W. J. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{Vascular burden and Alzheimer disease pathologic progression}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e31826c1b9d}, pmid = {22972646}, url = {https://doi.org/10.1212/wnl.0b013e31826c1b9d} } @article{thomas2014-25069482, author = {Thomas, J. B. and Brier, M. R. and Bateman, R. J. and Snyder, A. Z. and Benzinger, T. L. and Xiong, C. and Raichle, M. and Holtzman, D. M. and others}, title = {{Functional connectivity in autosomal dominant and late-onset Alzheimer disease}}, journal = {JAMA neurology}, year = {2014}, doi = {10.1001/jamaneurol.2014.1654}, pmid = {25069482}, url = {https://doi.org/10.1001/jamaneurol.2014.1654} } @article{donovan2016-27806159, author = {Donovan, N. J. and Okereke, O. I. and Vannini, P. and Amariglio, R. E. and Rentz, D. M. and Marshall, G. A. and Johnson, K. A. and Sperling, R. A.}, title = {{Association of Higher Cortical Amyloid Burden With Loneliness in Cognitively Normal Older Adults}}, journal = {JAMA psychiatry}, year = {2016}, doi = {10.1001/jamapsychiatry.2016.2657}, pmid = {27806159}, url = {https://doi.org/10.1001/jamapsychiatry.2016.2657} } @article{moura2021-33901296, author = {Moura, L. M. V. R. and Festa, N. and Price, M. and Volya, M. and Benson, N. M. and Zafar, S. and Weiss, M. and Blacker, D. and others}, title = {{Identifying Medicare beneficiaries with dementia}}, journal = {Journal of the American Geriatrics Society}, year = {2021}, doi = {10.1111/jgs.17183}, pmid = {33901296}, url = {https://doi.org/10.1111/jgs.17183} } @article{mirelman2012-22768271, author = {Mirelman, A. and Herman, T. and Brozgol, M. and Dorfman, M. and Sprecher, E. and Schweiger, A. and Giladi, N. and Hausdorff, J. M.}, title = {{Executive function and falls in older adults: new findings from a five-year prospective study link fall risk to cognition}}, journal = {PloS one}, year = {2012}, doi = {10.1371/journal.pone.0040297}, pmid = {22768271}, url = {https://doi.org/10.1371/journal.pone.0040297} } @article{mclachlan2025-40189783, author = {McLachlan, M. and Bettcher, B. and McVea, A. and DiFilippo, A. and Zammit, M. and LeMerise, L. and Rouanet, J. and Price, J. and others}, title = {{The striatum is an early, accurate indicator of amyloid burden using [11C]PiB in Down syndrome: Comparison of two radiotracers}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.70141}, pmid = {40189783}, url = {https://doi.org/10.1002/alz.70141} } @article{hickman2018-30258234, author = {Hickman, S. and Izzy, S. and Sen, P. and Morsett, L. and El Khoury, J.}, title = {{Microglia in neurodegeneration}}, journal = {Nature neuroscience}, year = {2018}, doi = {10.1038/s41593-018-0242-x}, pmid = {30258234}, url = {https://doi.org/10.1038/s41593-018-0242-x} } @article{chan2015-26414614, author = {Chan, G. and White, C. C. and Winn, P. A. and Cimpean, M. and Replogle, J. M. and Glick, L. R. and Cuerdon, N. E. and Ryan, K. J. and others}, title = {{CD33 modulates TREM2: convergence of Alzheimer loci}}, journal = {Nature neuroscience}, year = {2015}, doi = {10.1038/nn.4126}, pmid = {26414614}, url = {https://doi.org/10.1038/nn.4126} } @article{echouffotcheugui2018-30355700, author = {Echouffo-Tcheugui, J. B. and Conner, S. C. and Himali, J. J. and Maillard, P. and DeCarli, C. S. and Beiser, A. S. and Vasan, R. S. and Seshadri, S.}, title = {{Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000006549}, pmid = {30355700}, url = {https://doi.org/10.1212/wnl.0000000000006549} } @article{huang2022-35701596, author = {Huang, S. Y. and Li, Y. Z. and Zhang, Y. R. and Huang, Y. Y. and Wu, B. S. and Zhang, W. and Deng, Y. T. and Chen, S. D. and others}, title = {{Sleep, physical activity, sedentary behavior, and risk of incident dementia: a prospective cohort study of 431,924 UK Biobank participants}}, journal = {Molecular psychiatry}, year = {2022}, doi = {10.1038/s41380-022-01655-y}, pmid = {35701596}, url = {https://doi.org/10.1038/s41380-022-01655-y} } @article{chaker2016-27638924, author = {Chaker, L. and Wolters, F. J. and Bos, D. and Korevaar, T. I. and Hofman, A. and van der Lugt, A. and Koudstaal, P. J. and Franco, O. H. and others}, title = {{Thyroid function and the risk of dementia: The Rotterdam Study}}, journal = {Neurology}, year = {2016}, doi = {10.1212/wnl.0000000000003227}, pmid = {27638924}, url = {https://doi.org/10.1212/wnl.0000000000003227} } @article{freakpoli2022-34842183, author = {Freak-Poli, R. and Wagemaker, N. and Wang, R. and Lysen, T. S. and Ikram, M. A. and Vernooij, M. W. and Dintica, C. S. and Vernooij-Dassen, M. and others}, title = {{Loneliness, Not Social Support, Is Associated with Cognitive Decline and Dementia Across Two Longitudinal Population-Based Cohorts}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2022}, doi = {10.3233/jad-210330}, pmid = {34842183}, url = {https://doi.org/10.3233/jad-210330} } @article{wolters2017-28356461, author = {Wolters, F. J. and van der Lee, S. J. and Koudstaal, P. J. and van Duijn, C. M. and Hofman, A. and Ikram, M. K. and Vernooij, M. W. and Ikram, M. A.}, title = {{Parental family history of dementia in relation to subclinical brain disease and dementia risk}}, journal = {Neurology}, year = {2017}, doi = {10.1212/wnl.0000000000003871}, pmid = {28356461}, url = {https://doi.org/10.1212/wnl.0000000000003871} } @article{baughn2023-36927019, author = {Baughn, M. W. and Melamed, Z. and López-Erauskin, J. and Beccari, M. S. and Ling, K. and Zuberi, A. and Presa, M. and Gonzalo-Gil, E. and others}, title = {{Mechanism of STMN2 cryptic splice-polyadenylation and its correction for TDP-43 proteinopathies}}, journal = {Science (New York, N.Y.)}, year = {2023}, doi = {10.1126/science.abq5622}, pmid = {36927019}, url = {https://doi.org/10.1126/science.abq5622} } @article{green2024-39198642, author = {Green, G. S. and Fujita, M. and Yang, H. S. and Taga, M. and Cain, A. and McCabe, C. and Comandante-Lou, N. and White, C. C. and others}, title = {{Cellular communities reveal trajectories of brain ageing and Alzheimer's disease}}, journal = {Nature}, year = {2024}, doi = {10.1038/s41586-024-07871-6}, pmid = {39198642}, url = {https://doi.org/10.1038/s41586-024-07871-6} } @article{leff2022-36222194, author = {Leff, Bruce A. and Ritchie, Christine Seel and Ciemins, Elizabeth L. and Dunning, Stephan C.}, title = {{Prevalence of use and characteristics of users of home‐based medical care in Medicare Advantage}}, journal = {Journal of the American Geriatrics Society}, year = {2022}, doi = {10.1111/jgs.18085}, pmid = {36222194}, url = {https://doi.org/10.1111/jgs.18085} } @article{migeot2025-40935836, author = {Migeot, Joaquín and Piña‐Escudero, Stefanie Danielle and Hernandez, Hernán and González-Gómez, Raúl and Legaz, Agustina and Fittipaldi, Sol and Resende, Elisa de Paula França and Duran-Aniotz, Claudia A. and others}, title = {{Social exposome and brain health outcomes of dementia across Latin America}}, journal = {Nature Communications}, year = {2025}, doi = {10.1038/s41467-025-63277-6}, pmid = {40935836}, url = {https://doi.org/10.1038/s41467-025-63277-6} } @article{perelman2026-41540920, author = {Perelman, Sarah E. and Meeker, Melissa A and Kennedy, Maura and Joseph, Joshua W. and Liu, Shan W.}, title = {{Emergency Department Hallways Are Associated With Incident Delirium and Severe Agitation in Older Adults Living With Dementia}}, journal = {Journal of the American Geriatrics Society}, year = {2026}, doi = {10.1111/jgs.70307}, pmid = {41540920}, url = {https://doi.org/10.1111/jgs.70307} } @article{masini2025-40052267, author = {Masini, Gabriele and Wang, Wendy and Ji, Yuekai and Eaton, Anne A. and Inciardi, Riccardo Maria and Soliman, Elsayed Z. and PASSMAN, ROD S. and Solomon, Scott David and others}, title = {{Markers of Left Atrial Myopathy: Prognostic Usefulness for Ischemic Stroke and Dementia in People in Sinus Rhythm}}, journal = {Stroke}, year = {2025}, doi = {10.1161/strokeaha.124.047747}, pmid = {40052267}, url = {https://doi.org/10.1161/strokeaha.124.047747} } @article{jessen2014-24798886, author = {Jessen, Frank and Amariglio, Rebecca England and van Boxtel, Martin P.J. and Breteler, Monique M.B. and Ceccaldi, Mathieu and Chételat, Gaël and Dubois, Bruno and Dufouil, Carole and others}, title = {{A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease}}, journal = {Alzheimer s \& Dementia}, year = {2014}, doi = {10.1016/j.jalz.2014.01.001}, pmid = {24798886}, url = {https://doi.org/10.1016/j.jalz.2014.01.001} } @article{walsh2002-11932745, author = {Walsh, Dominic M. and Klyubin, Igor V. and Fadeeva, Julia V. and Cullen, William K. and Anwyl, Roger and Wolfe, Michael S. and Rowan, Michael J. and Selkoe, Dennis J.}, title = {{Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo}}, journal = {Nature}, year = {2002}, doi = {10.1038/416535a}, pmid = {11932745}, url = {https://doi.org/10.1038/416535a} } @article{selkoe2002-12399581, author = {Selkoe, Dennis J.}, title = {{Alzheimer's Disease Is a Synaptic Failure}}, journal = {Science}, year = {2002}, doi = {10.1126/science.1074069}, pmid = {12399581}, url = {https://doi.org/10.1126/science.1074069} } @article{hansson2022-35908251, author = {Hansson, Oskar and Edelmayer, Rebecca M. and Boxer, Adam L. and Carrillo, María C. and Mielke, Michelle M. and Rabinovici, Gil D. and Salloway, Stephen and Sperling, Reisa Anne and Zetterberg, Henrik and Teunissen, Charlotte Elisabeth}, title = {{The Alzheimer's Association appropriate use recommendations for blood biomarkers in Alzheimer's disease}}, journal = {Alzheimer s \& Dementia}, year = {2022}, doi = {10.1002/alz.12756}, pmid = {35908251}, url = {https://doi.org/10.1002/alz.12756} } @article{decalignon2012-22365544, author = {de Calignon, Alix and Polydoro, Manuela and Suárez‐Calvet, Marc and William, Christopher M. and Adamowicz, David H. and Kopeikina, Kathy J. and Pitstick, Rose and Sahara, Naruhiko and Ashe, Karen H. and Carlson, George A. and Spires‐Jones, Tara L. and Hyman, Bradley T.}, title = {{Propagation of Tau Pathology in a Model of Early Alzheimer's Disease}}, journal = {Neuron}, year = {2012}, doi = {10.1016/j.neuron.2011.11.033}, pmid = {22365544}, url = {https://doi.org/10.1016/j.neuron.2011.11.033} } @article{lopera2023-37188781, author = {Lopera, F. and Marino, C. and Chandrahas, A. S. and O'Hare, M. and Villalba-Moreno, N. D. and Aguillon, D. and Baena, A. and Sanchez, J. S. and Vila-Castelar, C. and Ramirez Gomez, L. and Chmielewska, N. and Oliveira, G. M. and others}, title = {{Resilience to autosomal dominant Alzheimer's disease in a Reelin-COLBOS heterozygous man}}, journal = {Nature Medicine}, year = {2023}, doi = {10.1038/s41591-023-02318-3}, pmid = {37188781}, url = {https://doi.org/10.1038/s41591-023-02318-3} } @article{kimura2025-40205047, author = {Kimura, K. and Subramanian, A. and Yin, Z. and Khalilnezhad, A. and Wu, Y. and He, D. and Dixon, K. O. and Chitta, U. K. and Ding, X. and Adhikari, N. and Guzchenko, I. and Zhang, X. and others}, title = {{Immune checkpoint TIM-3 regulates microglia and Alzheimer's disease}}, journal = {Nature}, year = {2025}, doi = {10.1038/s41586-025-08852-z}, pmid = {40205047}, url = {https://doi.org/10.1038/s41586-025-08852-z} } @article{farrell2021-33199430, author = {Farrell, M. E. and Jiang, S. and Schultz, A. P. and Properzi, M. J. and Price, J. C. and Becker, J. A. and Jacobs, H. I. L. and Hanseeuw, B. J. and others}, title = {{Defining the Lowest Threshold for Amyloid-PET to Predict Future Cognitive Decline and Amyloid Accumulation}}, journal = {Neurology}, year = {2021}, doi = {10.1212/wnl.0000000000011214}, pmid = {33199430}, url = {https://doi.org/10.1212/wnl.0000000000011214} } @article{fong2022-36028563, author = {Fong, T. G. and Inouye, S. K.}, title = {{The inter-relationship between delirium and dementia: the importance of delirium prevention}}, journal = {Nature reviews. Neurology}, year = {2022}, doi = {10.1038/s41582-022-00698-7}, pmid = {36028563}, url = {https://doi.org/10.1038/s41582-022-00698-7} } @article{killiany2000-10762153, author = {Killiany, R. J. and Gomez-Isla, T. and Moss, M. and Kikinis, R. and Sandor, T. and Jolesz, F. and Tanzi, R. and Jones, K. and others}, title = {{Use of structural magnetic resonance imaging to predict who will get Alzheimer's disease}}, journal = {Annals of neurology}, year = {2000}, doi = {10.1002/1531-8249(200004)47:4<430::aid-ana5>3.0.co;2-i}, pmid = {10762153}, url = {https://doi.org/10.1002/1531-8249(200004)47:4<430::aid-ana5>3.0.co;2-i} } @article{wachterman2016-27367547, author = {Wachterman, M. W. and Pilver, C. and Smith, D. and Ersek, M. and Lipsitz, SR. and Keating, N. L.}, title = {{Quality of End-of-Life Care Provided to Patients With Different Serious Illnesses}}, journal = {JAMA internal medicine}, year = {2016}, doi = {10.1001/jamainternmed.2016.1200}, pmid = {27367547}, url = {https://doi.org/10.1001/jamainternmed.2016.1200} } @article{marcantonio2003-12534838, author = {Marcantonio, E. R. and Simon, S. E. and Bergmann, M. A. and Jones, R. N. and Murphy, K. M. and Morris, J. N.}, title = {{Delirium symptoms in post-acute care: prevalent, persistent, and associated with poor functional recovery}}, journal = {Journal of the American Geriatrics Society}, year = {2003}, doi = {10.1034/j.1601-5215.2002.51002.x}, pmid = {12534838}, url = {https://doi.org/10.1034/j.1601-5215.2002.51002.x} } @article{jannati2024-38167251, author = {Jannati, A. and Toro-Serey, C. and Gomes-Osman, J. and Banks, R. and Ciesla, M. and Showalter, J. and Bates, D. and Tobyne, S. and others}, title = {{Digital Clock and Recall is superior to the Mini-Mental State Examination for the detection of mild cognitive impairment and mild dementia}}, journal = {Alzheimer's research \& therapy}, year = {2024}, doi = {10.1186/s13195-023-01367-7}, pmid = {38167251}, url = {https://doi.org/10.1186/s13195-023-01367-7} } @article{levine2018-28605446, author = {Levine, D. M. and Lipsitz, SR. and Linder, J. A.}, title = {{Changes in Everyday and Digital Health Technology Use Among Seniors in Declining Health}}, journal = {The journals of gerontology. Series A, Biological sciences and medical sciences}, year = {2018}, doi = {10.1093/gerona/glx116}, pmid = {28605446}, url = {https://doi.org/10.1093/gerona/glx116} } @article{wisch2026-41205623, author = {Wisch, J. K. and Jiao, Z. and Kennedy, J. T. and Cohen, A. D. and Schlachetzki, Z. and Petersen, M. and Handen, B. L. and Christian, B. T. and others}, title = {{Imaging and plasma biomarkers for pathological accumulation in Down syndrome}}, journal = {Brain : a journal of neurology}, year = {2026}, doi = {10.1093/brain/awaf418}, pmid = {41205623}, url = {https://doi.org/10.1093/brain/awaf418} } @article{wachinger2016-27913407, author = {Wachinger, C. and Salat, D. H. and Weiner, M. and Reuter, M. and {Alzheimer’s Disease Neuroimaging Initiative}}, title = {{Whole-brain analysis reveals increased neuroanatomical asymmetries in dementia for hippocampus and amygdala}}, journal = {Brain : a journal of neurology}, year = {2016}, doi = {10.1093/brain/aww243}, pmid = {27913407}, url = {https://doi.org/10.1093/brain/aww243} } @article{grothe2018-30016411, author = {Grothe, M. J. and Sepulcre, J. and Gonzalez-Escamilla, G. and Jelistratova, I. and Schöll, M. and Hansson, O. and Teipel, S. J. and {Alzheimer’s Disease Neuroimaging Initiative}}, title = {{Molecular properties underlying regional vulnerability to Alzheimer's disease pathology}}, journal = {Brain : a journal of neurology}, year = {2018}, doi = {10.1093/brain/awy189}, pmid = {30016411}, url = {https://doi.org/10.1093/brain/awy189} } @article{lysen2020-32558256, author = {Lysen, T. S. and Luik, A. I. and Ikram, M. K. and Tiemeier, H. and Ikram, M. A.}, title = {{Actigraphy-estimated sleep and 24-hour activity rhythms and the risk of dementia}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2020}, doi = {10.1002/alz.12122}, pmid = {32558256}, url = {https://doi.org/10.1002/alz.12122} } @article{elkhoury2007-17351623, author = {El Khoury, J. and Toft, M. and Hickman, S. E. and Means, T. K. and Terada, K. and Geula, C. and Luster, A. D.}, title = {{Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease}}, journal = {Nature medicine}, year = {2007}, doi = {10.1038/nm1555}, pmid = {17351623}, url = {https://doi.org/10.1038/nm1555} } @article{heneka2025-39653749, author = {Heneka, M. T. and van der Flier, W. M. and Jessen, F. and Hoozemanns, J. and Thal, D. R. and Boche, D. and Brosseron, F. and Teunissen, C. and others}, title = {{Neuroinflammation in Alzheimer disease}}, journal = {Nature reviews. Immunology}, year = {2025}, doi = {10.1038/s41577-024-01104-7}, pmid = {39653749}, url = {https://doi.org/10.1038/s41577-024-01104-7} } @article{orkaby2016-28039854, author = {Orkaby, Ariela R. and Ozonoff, Al and Reisman, Joel I. and Miller, Donald Ray and Zhao, Shibei and Rose, Adam J.}, title = {{Continued Use of Warfarin in Veterans with Atrial Fibrillation After Dementia Diagnosis}}, journal = {Journal of the American Geriatrics Society}, year = {2016}, doi = {10.1111/jgs.14573}, pmid = {28039854}, url = {https://doi.org/10.1111/jgs.14573} } @article{spoto2025-41292499, author = {Spoto, F. and Tian, Jiazi and Hügel, Jonas and Ortega, Daniel T. and Ritchie, Christine S. and Blacker, Deborah and Dominici, Francesca and Patel, Chirag J. and others}, title = {{Quantifying diagnostic signal decay in dementia: a national study of Medicare hospitalization data}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70945}, pmid = {41292499}, url = {https://doi.org/10.1002/alz.70945} } @article{berge2025-40042468, author = {Berge, Line Iden and Angeles, Renira C. and Gedde, Marie Hidle and Fæø, Stein Erik and Mannseth, Janne and Vislapuu, Maarja and Puaschitz, Nathalie Genevieve and Hillestad, Eirin and others}, title = {{Burden and care time for dementia caregivers in the LIVE@Home.Path trial}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.14622}, pmid = {40042468}, url = {https://doi.org/10.1002/alz.14622} } @article{gonzalezgomez2025-40270712, author = {González-Gómez, Raúl and Cruzat, Josephine and Hernández, Hernán Guillermo and Migeot, Joaquín and Legaz, Agustina and Santamaría‐García, Hernando A and Fittipaldi, Sol and Maito, Marcelo Adrián and others}, title = {{Qualitative and quantitative educational disparities and brain signatures in healthy aging and dementia across global settings}}, journal = {EClinicalMedicine}, year = {2025}, doi = {10.1016/j.eclinm.2025.103187}, pmid = {40270712}, url = {https://doi.org/10.1016/j.eclinm.2025.103187} } @article{morrow2025-40079430, author = {Morrow, Christopher B. and Kamath, Vidyulata J. and Dickerson, Bradford Clark and Eldaief, Mark C. and Rezaii, Neguine and Wong, Bonnie and McGinnis, Scott and Darby, Ryan and others}, title = {{Neuropsychiatric symptoms cluster and fluctuate over time in behavioral variant frontotemporal dementia}}, journal = {Psychiatry and Clinical Neurosciences}, year = {2025}, doi = {10.1111/pcn.13810}, pmid = {40079430}, url = {https://doi.org/10.1111/pcn.13810} } @article{delafuentearrillaga2025-40882668, author = {de la Fuente‐Arrillaga, Carmen and Carlos, Silvia and Toledo, Estefanía and Barbería-Latasa, María and Razquín, Cristina and Ruiz‐Canela, Miguel and Gea, Alfredo and Martínez‐González, Miguel Ángel and others}, title = {{Cohort Profile Update: The ‘Seguimiento Universidad de Navarra’ (SUN) study after 24 years of follow-up}}, journal = {International Journal of Epidemiology}, year = {2025}, doi = {10.1093/ije/dyaf149}, pmid = {40882668}, url = {https://doi.org/10.1093/ije/dyaf149} } @article{scheuner1996-8705854, author = {Scheuner, Donalyn and Eckman, Christopher B. and Jensen, M. and Song, X.H. and Citron, Martin and Suzuki, Nobuhiro and Bird, Thomas D. and Hardy, John and Hutton, Melanie L. and Kukull, Walter A. and Larson, Eric B. and Levy‐Lahad, Ephrat and Viitanen, Matti H. and Peskind, Elaine R. and Poorkaj, Parvoneh and Schellenberg, Gerald D. and Tanzi, Rudolph E. and Wasco, Wilma and Lannfelt, Lars and Selkoe, Dennis J. and Younkin, Samuel G.}, title = {{Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease}}, journal = {Nature Medicine}, year = {1996}, doi = {10.1038/nm0896-864}, pmid = {8705854}, url = {https://doi.org/10.1038/nm0896-864} } @article{hickman2013-24162652, author = {Hickman, Suzanne E. and Kingery, Nathan D. and Ohsumi, Toshiro K. and Borowsky, Mark L. and Wang, Li-chong and Means, Terry K. and El Khoury, Joseph B.}, title = {{The microglial sensome revealed by direct RNA sequencing}}, journal = {Nature Neuroscience}, year = {2013}, doi = {10.1038/nn.3554}, pmid = {24162652}, url = {https://doi.org/10.1038/nn.3554} } @article{dubois2016-27012484, author = {Dubois, Bruno and Hampel, Harald Juergen and Feldman, Howard and Scheltens, Philip and Aisen, Paul S. S. and Andrieu, Sandrine and Bakardjian, Hovagim and Benali, Habib and Bertram, Lars and Blennow, Kaj and Broich, Karl and Cavedo, Enrica and Crutch, Sebastian James and Dartigues, Jean‐François and Duyckaerts, Charles J. and Epelbaum, Stéphane and Frisoni, Giovanni Battista and Gauthier, Serge G. and Genthon, Rémy and Gouw, Alida A. and Habert, Marie‐Odile and Holtzman, David M. and Kivipelto, Miia and Lista, Simone and Molinuevo, José Luís and O’Bryant, Sid E. and Rabinovici, Gil D. and Rowe, Christopher Cleon and Salloway, Stephen and Schneider, Lon S. S. and Sperling, Reisa Anne and Teichmann, Marc and Carrillo, María C. and Cummings, Jeffrey L. and Jack, Clifford R.}, title = {{Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria}}, journal = {Alzheimer s \& Dementia}, year = {2016}, doi = {10.1016/j.jalz.2016.02.002}, pmid = {27012484}, url = {https://doi.org/10.1016/j.jalz.2016.02.002} } @article{griciuc2013-23623698, author = {Griciuc, Ana and Serrano‐Pozo, Alberto and Parrado, Antonio and Lesinski, Andrea N. and Asselin, Caroline and Mullin, Kristina and Hooli, Basavaraj V. and Choi, Se Hoon and Hyman, Bradley T. and Tanzi, Rudolph E.}, title = {{Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta}}, journal = {Neuron}, year = {2013}, doi = {10.1016/j.neuron.2013.04.014}, pmid = {23623698}, url = {https://doi.org/10.1016/j.neuron.2013.04.014} } @article{purcell2007-17701901, author = {Purcell, Shaun and Neale, Benjamin M. and Todd-Brown, Katherine EO and Thomas, L. Odong and Ferreira, Manuel A. R. and Bender, David and Maller, Julian and Sklar, Pamela and de Bakker, Paul I. W. and Daly, Mark J. and Sham, Pak Chung}, title = {{PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses}}, journal = {The American Journal of Human Genetics}, year = {2007}, doi = {10.1086/519795}, pmid = {17701901}, url = {https://doi.org/10.1086/519795} } @article{fischl2012-22248573, author = {Fischl, Bruce R.}, title = {{FreeSurfer}}, journal = {NeuroImage}, year = {2012}, doi = {10.1016/j.neuroimage.2012.01.021}, pmid = {22248573}, url = {https://doi.org/10.1016/j.neuroimage.2012.01.021} } @article{schafer2012-22632727, author = {Schafer, Dorothy P. and Lehrman, Emily K. and Kautzman, Amanda G. and Koyama, Ryuta and Mardinly, Alan R. and Yamasaki, Ryo and Ransohoff, Richard M. and Greenberg, Michael E. and Barres, Ben A. and Stevens, Beth A.}, title = {{Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner}}, journal = {Neuron}, year = {2012}, doi = {10.1016/j.neuron.2012.03.026}, pmid = {22632727}, url = {https://doi.org/10.1016/j.neuron.2012.03.026} } @article{subramanian2005-16199517, author = {Subramanian, Aravind N. and Tamayo, Pablo and Mootha, Vamsi Krishna and Mukherjee, Sayan and Ebert, Benjamin L. and Gillette, Michael A. and Paulovich, Amanda G. and Pomeroy, Scott L. and Golub, Todd R. and Lander, Eric S. and Mesirov, Jill P.}, title = {{Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles}}, journal = {Proceedings of the National Academy of Sciences}, year = {2005}, doi = {10.1073/pnas.0506580102}, pmid = {16199517}, url = {https://doi.org/10.1073/pnas.0506580102} } @article{sperling2009-19640477, author = {Sperling, Reisa Anne and LaViolette, Peter S. and O’Keefe, Kelly and O’Brien, Jacqueline L. and Rentz, Dorene M. and Pihlajamaki, Maija M. and Marshall, Gad A. and Hyman, Bradley T. and Selkoe, Dennis J. and Hedden, Trey and Buckner, Randy Lee and Becker, John Alex and Johnson, Keith A.}, title = {{Amyloid Deposition Is Associated with Impaired Default Network Function in Older Persons without Dementia}}, journal = {Neuron}, year = {2009}, doi = {10.1016/j.neuron.2009.07.003}, pmid = {19640477}, url = {https://doi.org/10.1016/j.neuron.2009.07.003} } @article{wolfe1999-10206644, author = {Wolfe, Michael S. and Xia, Weiming and Ostaszewski, Beth L. and Diehl, Thekla S. and Kimberly, William Taylor and Selkoe, Dennis J.}, title = {{Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity}}, journal = {Nature}, year = {1999}, doi = {10.1038/19077}, pmid = {10206644}, url = {https://doi.org/10.1038/19077} } @article{amariglio2020-32417775, author = {Amariglio, R. E. and Buckley, R. F. and Rabin, J. S. and Papp, K. V. and Quiroz, Y. T. and Mormino, E. C. and Sparks, K. P. and Johnson, K. A. and others}, title = {{Examining Cognitive Decline Across Black and White Participants in the Harvard Aging Brain Study}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2020}, doi = {10.3233/jad-191291}, pmid = {32417775}, url = {https://doi.org/10.3233/jad-191291} } @article{dumurgier2022-35970577, author = {Dumurgier, J. and Sabia, S. and Zetterberg, H. and Teunissen, C. E. and Hanseeuw, B. and Orellana, A. and Schraen, S. and Gabelle, A. and others}, title = {{A Pragmatic, Data-Driven Method to Determine Cutoffs for CSF Biomarkers of Alzheimer Disease Based on Validation Against PET Imaging}}, journal = {Neurology}, year = {2022}, doi = {10.1212/wnl.0000000000200735}, pmid = {35970577}, url = {https://doi.org/10.1212/wnl.0000000000200735} } @article{buckley2018-29803541, author = {Buckley, R. F. and Mormino, E. C. and Amariglio, R. E. and Properzi, M. J. and Rabin, J. S. and Lim, Y. Y. and Papp, K. V. and Jacobs, H. I. L. and others}, title = {{Sex, amyloid, and APOE ε4 and risk of cognitive decline in preclinical Alzheimer's disease: Findings from three well-characterized cohorts}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2018}, doi = {10.1016/j.jalz.2018.04.010}, pmid = {29803541}, url = {https://doi.org/10.1016/j.jalz.2018.04.010} } @article{babapourmofrad2020-32788242, author = {Babapour Mofrad, R. and Tijms, B. M. and Scheltens, P. and Barkhof, F. and van der Flier, W. M. and Sikkes, S. A. M. and Teunissen, C. E.}, title = {{Sex differences in CSF biomarkers vary by Alzheimer disease stage and APOE ε4 genotype}}, journal = {Neurology}, year = {2020}, doi = {10.1212/wnl.0000000000010629}, pmid = {32788242}, url = {https://doi.org/10.1212/wnl.0000000000010629} } @article{black2010-20505438, author = {Black, R. S. and Sperling, R. A. and Safirstein, B. and Motter, R. N. and Pallay, A. and Nichols, A. and Grundman, M.}, title = {{A single ascending dose study of bapineuzumab in patients with Alzheimer disease}}, journal = {Alzheimer disease and associated disorders}, year = {2010}, doi = {10.1097/wad.0b013e3181c53b00}, pmid = {20505438}, url = {https://doi.org/10.1097/wad.0b013e3181c53b00} } @article{travis2024-39392675, author = {Travis, A. and O'Donnell, A. and Giraldo-Santiago, N. and Stone, S. M. and Torres, D. and Adler, SR. and Vranceanu, A. M. and Ritchie, C. S.}, title = {{Intervention for the Management of Neuropsychiatric Symptoms to Reduce Caregiver Stress: Protocol for the Mindful and Self-Compassion Care Intervention for Caregivers of Persons Living With Dementia}}, journal = {JMIR research protocols}, year = {2024}, doi = {10.2196/58356}, pmid = {39392675}, url = {https://doi.org/10.2196/58356} } @article{jack2011-21514247, author = {Jack, C. R. and Albert, M. S. and Knopman, D. S. and McKhann, G. M. and Sperling, R. A. and Carrillo, M. C. and Thies, B. and Phelps, C. H.}, title = {{Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2011}, doi = {10.1016/j.jalz.2011.03.004}, pmid = {21514247}, url = {https://doi.org/10.1016/j.jalz.2011.03.004} } @article{tandon2013-23800613, author = {Tandon, R. and Gaebel, W. and Barch, D. M. and Bustillo, J. and Gur, R. E. and Heckers, S. and Malaspina, D. and Owen, M. J. and others}, title = {{Definition and description of schizophrenia in the DSM-5}}, journal = {Schizophrenia research}, year = {2013}, doi = {10.1016/j.schres.2013.05.028}, pmid = {23800613}, url = {https://doi.org/10.1016/j.schres.2013.05.028} } @article{lippa2007-17353469, author = {Lippa, C. F. and Duda, J. E. and Grossman, M. and Hurtig, H. I. and Aarsland, D. and Boeve, B. F. and Brooks, D. J. and Dickson, D. W. and others}, title = {{DLB and PDD boundary issues: diagnosis, treatment, molecular pathology, and biomarkers}}, journal = {Neurology}, year = {2007}, doi = {10.1212/01.wnl.0000256715.13907.d3}, pmid = {17353469}, url = {https://doi.org/10.1212/01.wnl.0000256715.13907.d3} } @article{marshall2011-21575871, author = {Marshall, G. A. and Rentz, D. M. and Frey, M. T. and Locascio, J. J. and Johnson, K. A. and Sperling, R. A. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{Executive function and instrumental activities of daily living in mild cognitive impairment and Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2011}, doi = {10.1016/j.jalz.2010.04.005}, pmid = {21575871}, url = {https://doi.org/10.1016/j.jalz.2010.04.005} } @article{chhatwal2013-23884042, author = {Chhatwal, J. P. and Schultz, A. P. and Johnson, K. and Benzinger, T. L. and Jack, C. and Ances, B. M. and Sullivan, C. A. and Salloway, S. P. and others}, title = {{Impaired default network functional connectivity in autosomal dominant Alzheimer disease}}, journal = {Neurology}, year = {2013}, doi = {10.1212/wnl.0b013e3182a1aafe}, pmid = {23884042}, url = {https://doi.org/10.1212/wnl.0b013e3182a1aafe} } @article{lao2020-32944999, author = {Lao, P. J. and Gutierrez, J. and Keator, D. and Rizvi, B. and Banerjee, A. and Igwe, K. C. and Laing, K. K. and Sathishkumar, M. and others}, title = {{Alzheimer-Related Cerebrovascular Disease in Down Syndrome}}, journal = {Annals of neurology}, year = {2020}, doi = {10.1002/ana.25905}, pmid = {32944999}, url = {https://doi.org/10.1002/ana.25905} } @article{conway1998-9809558, author = {Conway, K. A. and Harper, J. D. and Lansbury, P. T.}, title = {{Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease}}, journal = {Nature medicine}, year = {1998}, doi = {10.1038/3311}, pmid = {9809558}, url = {https://doi.org/10.1038/3311} } @article{watts2004-15034582, author = {Watts, G. D. and Wymer, J. and Kovach, M. J. and Mehta, S. G. and Mumm, S. and Darvish, D. and Pestronk, A. and Whyte, M. P. and others}, title = {{Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein}}, journal = {Nature genetics}, year = {2004}, doi = {10.1038/ng1332}, pmid = {15034582}, url = {https://doi.org/10.1038/ng1332} } @article{tagge2018-29360998, author = {Tagge, C. A. and Fisher, A. M. and Minaeva, O. V. and Gaudreau-Balderrama, A. and Moncaster, J. A. and Zhang, X. L. and Wojnarowicz, M. W. and Casey, N. and others}, title = {{Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model}}, journal = {Brain : a journal of neurology}, year = {2018}, doi = {10.1093/brain/awx350}, pmid = {29360998}, url = {https://doi.org/10.1093/brain/awx350} } @article{zhang2013-23438677, author = {Zhang, B. and Tian, M. and Zheng, H. and Zhen, Y. and Yue, Y. and Li, T. and Li, S. and Marcantonio, E. R. and others}, title = {{Effects of anesthetic isoflurane and desflurane on human cerebrospinal fluid Aβ and τ level}}, journal = {Anesthesiology}, year = {2013}, doi = {10.1097/aln.0b013e31828ce55d}, pmid = {23438677}, url = {https://doi.org/10.1097/aln.0b013e31828ce55d} } @article{rabinovici2025-40155270, author = {Rabinovici, G. D. and Selkoe, D. J. and Schindler, S. E. and Aisen, P. and Apostolova, L. G. and Atri, A. and Greenberg, S. M. and Hendrix, S. B. and others}, title = {{Donanemab: Appropriate use recommendations}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2025}, doi = {10.1016/j.tjpad.2025.100150}, pmid = {40155270}, url = {https://doi.org/10.1016/j.tjpad.2025.100150} } @article{albert2007-17402816, author = {Albert, M. and Blacker, D. and Moss, M. B. and Tanzi, R. and McArdle, J. J.}, title = {{Longitudinal change in cognitive performance among individuals with mild cognitive impairment}}, journal = {Neuropsychology}, year = {2007}, doi = {10.1037/0894-4105.21.2.158}, pmid = {17402816}, url = {https://doi.org/10.1037/0894-4105.21.2.158} } @article{wolters2016-27727284, author = {Wolters, F. J. and Mattace-Raso, F. U. and Koudstaal, P. J. and Hofman, A. and Ikram, M. A. and {Heart Brain Connection Collaborative Research Group}}, title = {{Orthostatic Hypotension and the Long-Term Risk of Dementia: A Population-Based Study}}, journal = {PLoS medicine}, year = {2016}, doi = {10.1371/journal.pmed.1002143}, pmid = {27727284}, url = {https://doi.org/10.1371/journal.pmed.1002143} } @article{zhang2016-26998601, author = {Zhang, Y. J. and Gendron, T. F. and Grima, J. C. and Sasaguri, H. and Jansen-West, K. and Xu, Y. F. and Katzman, R. B. and Gass, J. and others}, title = {{C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins}}, journal = {Nature neuroscience}, year = {2016}, doi = {10.1038/nn.4272}, pmid = {26998601}, url = {https://doi.org/10.1038/nn.4272} } @article{liss2021-33458891, author = {Liss, J. L. and Seleri Assunção, S. and Cummings, J. and Atri, A. and Geldmacher, D. S. and Candela, S. F. and Devanand, D. P. and Fillit, H. M. and others}, title = {{Practical recommendations for timely, accurate diagnosis of symptomatic Alzheimer's disease (MCI and dementia) in primary care: a review and synthesis}}, journal = {Journal of internal medicine}, year = {2021}, doi = {10.1111/joim.13244}, pmid = {33458891}, url = {https://doi.org/10.1111/joim.13244} } @article{gibbons2024-39046728, author = {Gibbons, Robert David and Olfson, Mark and Saulsberry, Loren and Edlund, Mark J. and Zangeneh, Sahar Z. and Bareis, Natalie and Chwastiak, Lydia and Gibbons, Jason Brian and others}, title = {{Social Vulnerability and Prevalence and Treatment for Mental Health and Substance Use Disorders}}, journal = {JAMA Psychiatry}, year = {2024}, doi = {10.1001/jamapsychiatry.2024.1870}, pmid = {39046728}, url = {https://doi.org/10.1001/jamapsychiatry.2024.1870} } @article{ottman2026-42712082, author = {Ottman, Ruth and Wetmore, John Brandon and Leu, Cheng-Shiun and Uhlmann, Wendy R. and Goldman, Jill and Rodriguez, Sophia and Caro, Daniela Diaz and Caban, Maria L. and others}, title = {{Psychological impacts of APOE genotype disclosure among Latinos in New York City: a randomized controlled trial}}, journal = {Alzheimer s \& Dementia}, year = {2026}, doi = {10.1002/alz.71796}, pmid = {42712082}, url = {https://doi.org/10.1002/alz.71796} } @article{dong2025-39986315, author = {Dong, Shuxin and Braun, Danielle and Wu, Xiao Jun and Yitshak‐Sade, Maayan and Blacker, Deborah and Kioumourtzoglou, Marianthi‐Anna and Schwartz, Joel and Mork, Daniel and others}, title = {{The impacts of air pollution on mortality and hospital readmission among Medicare beneficiaries with Alzheimer's disease and Alzheimer's disease-related dementias: a national retrospective cohort study in the USA}}, journal = {The Lancet Planetary Health}, year = {2025}, doi = {10.1016/s2542-5196(25)00001-4}, pmid = {39986315}, url = {https://doi.org/10.1016/s2542-5196(25)00001-4} } @article{selkoe2001-11274343, author = {Selkoe, Dennis J.}, title = {{Alzheimer's Disease: Genes, Proteins, and Therapy}}, journal = {Physiological Reviews}, year = {2001}, doi = {10.1152/physrev.2001.81.2.741}, pmid = {11274343}, url = {https://doi.org/10.1152/physrev.2001.81.2.741} } @article{dickerson2008-18632739, author = {Dickerson, Bradford Clark and Bakkour, Akram and Salat, David H. and Feczko, Eric and Pacheco, Jenni and Greve, Douglas N. and Grodstein, Fran and Wright, Christopher Ian and Blacker, Deborah and Rosas, Herminia Diana and Sperling, Reisa Anne and Atri, Alireza and Growdon, John H. and Hyman, Bradley T. and Morris, John C. and Fischl, Bruce R. and Buckner, Randy Lee}, title = {{The Cortical Signature of Alzheimer's Disease: Regionally Specific Cortical Thinning Relates to Symptom Severity in Very Mild to Mild AD Dementia and is Detectable in Asymptomatic Amyloid-Positive Individuals}}, journal = {Cerebral Cortex}, year = {2008}, doi = {10.1093/cercor/bhn113}, pmid = {18632739}, url = {https://doi.org/10.1093/cercor/bhn113} } @article{haass1992-1383826, author = {Haass, Christian and Schlossmacher, Michael G. and Hung, Albert Y. and Vigo‐Pelfrey, Carmen and Mellon, Angela and Ostaszewski, Beth L. and Lieberburg, Ivan M. and Koo, Edward H. and Schenk, Dale and Teplow, David B. and Selkoe, Dennis J.}, title = {{Amyloid β-peptide is produced by cultured cells during normal metabolism}}, journal = {Nature}, year = {1992}, doi = {10.1038/359322a0}, pmid = {1383826}, url = {https://doi.org/10.1038/359322a0} } @article{citron1992-1465129, author = {Citron, Martin and Oltersdorf, Tilman and Haass, Christian and McConlogue, Lisa and Hung, Albert Y. and Seubert, Peter A. and Vigo‐Pelfrey, Carmen and Lieberburg, Ivan M. and Selkoe, Dennis J.}, title = {{Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production}}, journal = {Nature}, year = {1992}, doi = {10.1038/360672a0}, pmid = {1465129}, url = {https://doi.org/10.1038/360672a0} } @article{caviedes2026-41688826, author = {Caviedes, A. and Cabral-Miranda, F. and Orellana, P. and Hernández, H. and Henríquez, F. and Gonzalez-Gomez, R. and Pizarro, M. and Migeot, J. and Ochoa-Rosales, C. and Gonzalez-Silva, C. and Marin-Diaz, N. and Coronel-Oliveros, C. and others}, title = {{Blood-based AT(N) biomarkers for Alzheimer's disease and frontotemporal lobar degeneration in Latin America}}, journal = {Nature Aging}, year = {2026}, doi = {10.1038/s43587-025-01061-3}, pmid = {41688826}, url = {https://doi.org/10.1038/s43587-025-01061-3} } @article{serranopozo2011-22229116, author = {Serrano-Pozo, A. and Frosch, M. P. and Masliah, E. and Hyman, B. T.}, title = {{Neuropathological alterations in Alzheimer disease}}, journal = {Cold Spring Harbor perspectives in medicine}, year = {2011}, doi = {10.1101/cshperspect.a006189}, pmid = {22229116}, url = {https://doi.org/10.1101/cshperspect.a006189} } @article{ingelsson2004-15037694, author = {Ingelsson, M. and Fukumoto, H. and Newell, K. L. and Growdon, J. H. and Hedley-Whyte, E. T. and Frosch, M. P. and Albert, M. S. and Hyman, B. T. and others}, title = {{Early Abeta accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain}}, journal = {Neurology}, year = {2004}, doi = {10.1212/01.wnl.0000115115.98960.37}, pmid = {15037694}, url = {https://doi.org/10.1212/01.wnl.0000115115.98960.37} } @article{ali2023-37101235, author = {Ali, M. and Archer, D. B. and Gorijala, P. and Western, D. and Timsina, J. and Fernández, M. V. and Wang, T. C. and Satizabal, C. L. and others}, title = {{Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease}}, journal = {Acta neuropathologica communications}, year = {2023}, doi = {10.1186/s40478-023-01563-4}, pmid = {37101235}, url = {https://doi.org/10.1186/s40478-023-01563-4} } @article{ma1994-7969426, author = {Ma, J. and Yee, A. and Brewer, H. B. and Das, S. and Potter, H.}, title = {{Amyloid-associated proteins alpha 1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer beta-protein into filaments}}, journal = {Nature}, year = {1994}, doi = {10.1038/372092a0}, pmid = {7969426}, url = {https://doi.org/10.1038/372092a0} } @article{bertram2010-20955934, author = {Bertram, L. and Lill, C. M. and Tanzi, R. E.}, title = {{The genetics of Alzheimer disease: back to the future}}, journal = {Neuron}, year = {2010}, doi = {10.1016/j.neuron.2010.10.013}, pmid = {20955934}, url = {https://doi.org/10.1016/j.neuron.2010.10.013} } @article{shulman2013-23836404, author = {Shulman, J. M. and Chen, K. and Keenan, B. T. and Chibnik, L. B. and Fleisher, A. and Thiyyagura, P. and Roontiva, A. and McCabe, C. and others}, title = {{Genetic susceptibility for Alzheimer disease neuritic plaque pathology}}, journal = {JAMA neurology}, year = {2013}, doi = {10.1001/jamaneurol.2013.2815}, pmid = {23836404}, url = {https://doi.org/10.1001/jamaneurol.2013.2815} } @article{alber2019-31011621, author = {Alber, J. and Alladi, S. and Bae, H. J. and Barton, D. A. and Beckett, L. A. and Bell, J. M. and Berman, S. E. and Biessels, G. J. and others}, title = {{White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2019}, doi = {10.1016/j.trci.2019.02.001}, pmid = {31011621}, url = {https://doi.org/10.1016/j.trci.2019.02.001} } @article{viswanathan2009-19171835, author = {Viswanathan, A. and Rocca, W. A. and Tzourio, C.}, title = {{Vascular risk factors and dementia: how to move forward?}}, journal = {Neurology}, year = {2009}, doi = {10.1212/01.wnl.0000341271.90478.8e}, pmid = {19171835}, url = {https://doi.org/10.1212/01.wnl.0000341271.90478.8e} } @article{marcantonio2012-22669559, author = {Marcantonio, E. R.}, title = {{Postoperative delirium: a 76-year-old woman with delirium following surgery}}, journal = {JAMA}, year = {2012}, doi = {10.1001/jama.2012.6857}, pmid = {22669559}, url = {https://doi.org/10.1001/jama.2012.6857} } @article{ko2025-39680399, author = {Ko, D. and Chung, M. K. and Evans, P. T. and Benjamin, E. J. and Helm, R. H.}, title = {{Atrial Fibrillation: A Review}}, journal = {JAMA}, year = {2025}, doi = {10.1001/jama.2024.22451}, pmid = {39680399}, url = {https://doi.org/10.1001/jama.2024.22451} } @article{marquie2015-26344059, author = {Marquié, M. and Normandin, M. D. and Vanderburg, C. R. and Costantino, I. M. and Bien, E. A. and Rycyna, L. G. and Klunk, W. E. and Mathis, C. A. and others}, title = {{Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue}}, journal = {Annals of neurology}, year = {2015}, doi = {10.1002/ana.24517}, pmid = {26344059}, url = {https://doi.org/10.1002/ana.24517} } @article{schonhaut2017-28980714, author = {Schonhaut, D. R. and McMillan, C. T. and Spina, S. and Dickerson, B. C. and Siderowf, A. and Devous, M. D. and Tsai, R. and Winer, J. and others}, title = {{18 F-flortaucipir tau positron emission tomography distinguishes established progressive supranuclear palsy from controls and Parkinson disease: A multicenter study}}, journal = {Annals of neurology}, year = {2017}, doi = {10.1002/ana.25060}, pmid = {28980714}, url = {https://doi.org/10.1002/ana.25060} } @article{serranopozo2011-21777559, author = {Serrano-Pozo, A. and Mielke, M. L. and Gómez-Isla, T. and Betensky, R. A. and Growdon, J. H. and Frosch, M. P. and Hyman, B. T.}, title = {{Reactive glia not only associates with plaques but also parallels tangles in Alzheimer's disease}}, journal = {The American journal of pathology}, year = {2011}, doi = {10.1016/j.ajpath.2011.05.047}, pmid = {21777559}, url = {https://doi.org/10.1016/j.ajpath.2011.05.047} } @article{gomperts2008-18794492, author = {Gomperts, S. N. and Rentz, D. M. and Moran, E. and Becker, J. A. and Locascio, J. J. and Klunk, W. E. and Mathis, C. A. and Elmaleh, D. R. and others}, title = {{Imaging amyloid deposition in Lewy body diseases}}, journal = {Neurology}, year = {2008}, doi = {10.1212/01.wnl.0000326146.60732.d6}, pmid = {18794492}, url = {https://doi.org/10.1212/01.wnl.0000326146.60732.d6} } @article{drzezga2011-21490054, author = {Drzezga, A. and Becker, J. A. and Van Dijk, K. R. and Sreenivasan, A. and Talukdar, T. and Sullivan, C. and Schultz, A. P. and Sepulcre, J. and others}, title = {{Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden}}, journal = {Brain : a journal of neurology}, year = {2011}, doi = {10.1093/brain/awr066}, pmid = {21490054}, url = {https://doi.org/10.1093/brain/awr066} } @article{mcdonald2010-20403962, author = {Mc Donald, J. M. and Savva, G. M. and Brayne, C. and Welzel, A. T. and Forster, G. and Shankar, G. M. and Selkoe, D. J. and Ince, P. G. and others}, title = {{The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia}}, journal = {Brain : a journal of neurology}, year = {2010}, doi = {10.1093/brain/awq065}, pmid = {20403962}, url = {https://doi.org/10.1093/brain/awq065} } @article{kalaria2024-38696263, author = {Kalaria, R. and Maestre, G. and Mahinrad, S. and Acosta, D. M. and Akinyemi, R. O. and Alladi, S. and Allegri, R. F. and Arshad, F. and others}, title = {{The 2022 symposium on dementia and brain aging in low- and middle-income countries: Highlights on research, diagnosis, care, and impact}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.13836}, pmid = {38696263}, url = {https://doi.org/10.1002/alz.13836} } @article{so2022-35544998, author = {So, R. and Andersen, Z. J. and Chen, J. and Stafoggia, M. and de Hoogh, K. and Katsouyanni, K. and Vienneau, D. and Rodopoulou, S. and others}, title = {{Long-term exposure to air pollution and mortality in a Danish nationwide administrative cohort study: Beyond mortality from cardiopulmonary disease and lung cancer}}, journal = {Environment international}, year = {2022}, doi = {10.1016/j.envint.2022.107241}, pmid = {35544998}, url = {https://doi.org/10.1016/j.envint.2022.107241} } @article{lui2016-27114033, author = {Lui, H. and Zhang, J. and Makinson, SR. and Cahill, M. K. and Kelley, K. W. and Huang, H. Y. and Shang, Y. and Oldham, M. C. and others}, title = {{Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation}}, journal = {Cell}, year = {2016}, doi = {10.1016/j.cell.2016.04.001}, pmid = {27114033}, url = {https://doi.org/10.1016/j.cell.2016.04.001} } @article{dawson2018-30250265, author = {Dawson, T. M. and Golde, T. E. and Lagier-Tourenne, C.}, title = {{Animal models of neurodegenerative diseases}}, journal = {Nature neuroscience}, year = {2018}, doi = {10.1038/s41593-018-0236-8}, pmid = {30250265}, url = {https://doi.org/10.1038/s41593-018-0236-8} } @article{steenland2012-22543846, author = {Steenland, K. and Karnes, C. and Seals, R. and Carnevale, C. and Hermida, A. and Levey, A.}, title = {{Late-life depression as a risk factor for mild cognitive impairment or Alzheimer's disease in 30 US Alzheimer's disease centers}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2012}, doi = {10.3233/jad-2012-111922}, pmid = {22543846}, url = {https://doi.org/10.3233/jad-2012-111922} } @article{koronyo2023-36773106, author = {Koronyo, Y. and Rentsendorj, A. and Mirzaei, N. and Regis, G. C. and Sheyn, J. and Shi, H. and Barron, E. and Cook-Wiens, G. and others}, title = {{Retinal pathological features and proteome signatures of Alzheimer's disease}}, journal = {Acta neuropathologica}, year = {2023}, doi = {10.1007/s00401-023-02548-2}, pmid = {36773106}, url = {https://doi.org/10.1007/s00401-023-02548-2} } @article{hanseeuw2018-29792874, author = {Hanseeuw, B. J. and Betensky, R. A. and Mormino, E. C. and Schultz, A. P. and Sepulcre, J. and Becker, J. A. and Jacobs, H. I. L. and Buckley, R. F. and others}, title = {{PET staging of amyloidosis using striatum}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2018}, doi = {10.1016/j.jalz.2018.04.011}, pmid = {29792874}, url = {https://doi.org/10.1016/j.jalz.2018.04.011} } @article{licher2019-30525906, author = {Licher, S. and Leening, M. J. G. and Yilmaz, P. and Wolters, F. J. and Heeringa, J. and Bindels, P. J. E. and {Alzheimer’s Disease Neuroimaging Initiative} and Vernooij, M. W. and others}, title = {{Development and Validation of a Dementia Risk Prediction Model in the General Population: An Analysis of Three Longitudinal Studies}}, journal = {The American journal of psychiatry}, year = {2019}, doi = {10.1176/appi.ajp.2018.18050566}, pmid = {30525906}, url = {https://doi.org/10.1176/appi.ajp.2018.18050566} } @article{vanarendonk2023-36374264, author = {van Arendonk, J. and Neitzel, J. and Steketee, R. M. E. and van Assema, D. M. E. and Vrooman, H. A. and Segbers, M. and Ikram, M. A. and Vernooij, M. W.}, title = {{Diabetes and hypertension are related to amyloid-beta burden in the population-based Rotterdam Study}}, journal = {Brain : a journal of neurology}, year = {2023}, doi = {10.1093/brain/awac354}, pmid = {36374264}, url = {https://doi.org/10.1093/brain/awac354} } @article{terracciano2021-33819874, author = {Terracciano, A. and Aschwanden, D. and Passamonti, L. and Toschi, N. and Stephan, Y. and Luchetti, M. and Lee, J. H. and Sesker, A. and others}, title = {{Is neuroticism differentially associated with risk of Alzheimer's disease, vascular dementia, and frontotemporal dementia?}}, journal = {Journal of psychiatric research}, year = {2021}, doi = {10.1016/j.jpsychires.2021.03.039}, pmid = {33819874}, url = {https://doi.org/10.1016/j.jpsychires.2021.03.039} } @article{sun2023-36379419, author = {Sun, Y. and Chen, C. and Yu, Y. and Zhang, H. and Tan, X. and Zhang, J. and Qi, L. and Lu, Y. and others}, title = {{Replacement of leisure-time sedentary behavior with various physical activities and the risk of dementia incidence and mortality: A prospective cohort study}}, journal = {Journal of sport and health science}, year = {2023}, doi = {10.1016/j.jshs.2022.11.005}, pmid = {36379419}, url = {https://doi.org/10.1016/j.jshs.2022.11.005} } @article{liu2025-40855194, author = {Liu, Yuxi and Gu, Xiao and Li, Yanping and Wang, Fenglei and Vyas, Chirag M. and Peng, Cheng and Dong, Danyue and Li, Yuhan and others}, title = {{Interplay of genetic predisposition, plasma metabolome and Mediterranean diet in dementia risk and cognitive function}}, journal = {Nature Medicine}, year = {2025}, doi = {10.1038/s41591-025-03891-5}, pmid = {40855194}, url = {https://doi.org/10.1038/s41591-025-03891-5} } @article{li2026-41535386, author = {Li, Jun and Hu, Jie and Yun, Huan and Mei, Zhendong and Wang, Xingyan and Luo, Kai and Guasch‐Ferré, Marta and Han, Xikun and others}, title = {{Circulating metabolites, genetics and lifestyle factors in relation to future risk of type 2 diabetes}}, journal = {Nature Medicine}, year = {2026}, doi = {10.1038/s41591-025-04105-8}, pmid = {41535386}, url = {https://doi.org/10.1038/s41591-025-04105-8} } @article{knaul2025-40021301, author = {Knaul, Felícia Marie and Arreola‐Ornelas, Héctor and Kwete, Xiaoxiao Jiang and Bhadelia, Afsan and Rosa, William E. and Touchton, Michael M. and Méndez-Carniado, Oscar and Vargas, Valentina and others}, title = {{The evolution of serious health-related suffering from 1990 to 2021: an update to The Lancet Commission on global access to palliative care and pain relief}}, journal = {The Lancet Global Health}, year = {2025}, doi = {10.1016/s2214-109x(24)00476-5}, pmid = {40021301}, url = {https://doi.org/10.1016/s2214-109x(24)00476-5} } @article{zhang2025-40906862, author = {Zhang, Xiaodi and Liu, Haiqing and Wu, Xiao Jun and Jia, Longgang and Gadhave, Kundlik and Wang, Lena and Zhang, Kevin and others}, title = {{Lewy body dementia promotion by air pollutants}}, journal = {Science}, year = {2025}, doi = {10.1126/science.adu4132}, pmid = {40906862}, url = {https://doi.org/10.1126/science.adu4132} } @article{liu2025-39903689, author = {Liu, Haiyan and Marsh, Thomas W. and Shi, Xinyu and Renton, Alan Edward and Bowling, Kevin M. and Ziegemeier, Ellen and Wang, Guoqiao and Cao, Yuchen and others}, title = {{The landscape of autosomal-dominant Alzheimer’s disease: global distribution and age of onset}}, journal = {Brain}, year = {2025}, doi = {10.1093/brain/awaf038}, pmid = {39903689}, url = {https://doi.org/10.1093/brain/awaf038} } @article{chan2025-41137616, author = {Chan, Diane and de Weck, Gabrielle and Jackson, Brennan and Suk, Ho‐Jun and Milman, Noah Pollak and Kitchener, Erin G. and Avalos, Vanesa S. Fernandez and Quay, M. J. and others}, title = {{Gamma sensory stimulation in mild Alzheimer's dementia: An open‐label extension study}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70792}, pmid = {41137616}, url = {https://doi.org/10.1002/alz.70792} } @article{koch2025-40176122, author = {Koch, Giacomo and Casula, Elias Paolo and Bonnı̀, Sonia and Borghi, Ilaria and Assogna, Martina and Di Lorenzo, Francesco and Esposito, Romina and Maiella, Michele and others}, title = {{Effects of 52 weeks of precuneus rTMS in Alzheimer’s disease patients: a randomized trial}}, journal = {Alzheimer s Research \& Therapy}, year = {2025}, doi = {10.1186/s13195-025-01709-7}, pmid = {40176122}, url = {https://doi.org/10.1186/s13195-025-01709-7} } @article{groot2026-41990307, author = {Groot, Colin and Calandri, Ismael L. and Bader, Ilse and Bocancea, Diana I. and de Bruin, Hannah and Carrigan, Maria and Collij, Lyduine Eisa and Duits, Flora Hillegonde and others}, title = {{Characterizing Individuals Fulfilling Clinical Criteria for Limbic-Predominant Age-Related TDP-43 Encephalopathy in a Tertiary Memory Clinic}}, journal = {Neurology}, year = {2026}, doi = {10.1212/wnl.0000000000214810}, pmid = {41990307}, url = {https://doi.org/10.1212/wnl.0000000000214810} } @article{fleck2025-39786167, author = {Fleck, Lara and Buß, Claudia and Bauer, M. and Stein, Maike and Mekle, Ralf and Kock, Lena and Klawitter, Heiko and Godara, Malvika and others}, title = {{Early‐Life Adversity Predicts Markers of Aging‐Related Neuroinflammation, Neurodegeneration, and Cognitive Impairment in Women}}, journal = {Annals of Neurology}, year = {2025}, doi = {10.1002/ana.27161}, pmid = {39786167}, url = {https://doi.org/10.1002/ana.27161} } @article{wang2025-41299092, author = {Wang, Yunhe and Xiao, Sihao and Liu, Bowen and Jiang, Rongtao and Liu, Yuxi and Hang, Yian and Chen, Li and Chen, Runsen and others}, title = {{Organ-specific proteomic aging clocks predict disease and longevity across diverse populations}}, journal = {Nature Aging}, year = {2025}, doi = {10.1038/s43587-025-01016-8}, pmid = {41299092}, url = {https://doi.org/10.1038/s43587-025-01016-8} } @article{love2014-25516281, author = {Love, Michael I. and Huber, Wolfgang K. and Anders, Simon}, title = {{Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2}}, journal = {Genome biology}, year = {2014}, doi = {10.1186/s13059-014-0550-8}, pmid = {25516281}, url = {https://doi.org/10.1186/s13059-014-0550-8} } @article{fischl2000-10984517, author = {Fischl, Bruce R. and Dale, Anders Martin}, title = {{Measuring the thickness of the human cerebral cortex from magnetic resonance images}}, journal = {Proceedings of the National Academy of Sciences}, year = {2000}, doi = {10.1073/pnas.200033797}, pmid = {10984517}, url = {https://doi.org/10.1073/pnas.200033797} } @article{cruchaga2013-23562540, author = {Cruchaga, Carlos C and Kauwe, John S. K. and Harari, Oscar and Jin, Sheng Chih and Cai, Yefei and Karch, Celeste M M. and Benítez, Bruno A. and Jeng, Amanda T. and Skorupa, Tara and Carrell, David and Bertelsen, Sarah E. and Bailey, Matthew H. and McKean, David M. and Shulman, Joshua M and De Jager, Philip L. and Chibnik, Lori Beth and Bennett, David and Arnold, S. E. and Harold, Denise H. and Sims, Rebecca and Gerrish, Amy and Williams, Julie H. and Van Deerlin, Vivianna M. and Lee, Virginia M.‐Y. and Shaw, Leslie M. and Trojanowski, John Q. and Haines, Jonathan L. and Mayeux, Richard P and Pericak‐Vance, Margaret A. and Farrer, Lindsay A. and Schellenberg, Gerard D. and Peskind, Elaine R. and Galasko, Douglas R and Fagan, Anne M. and Holtzman, David M. and Morris, John C. and Goate, Alison}, title = {{GWAS of Cerebrospinal Fluid Tau Levels Identifies Risk Variants for Alzheimer’s Disease}}, journal = {Neuron}, year = {2013}, doi = {10.1016/j.neuron.2013.02.026}, pmid = {23562540}, url = {https://doi.org/10.1016/j.neuron.2013.02.026} } @article{hickman2008-18701698, author = {Hickman, Suzanne E. and Allison, Elizabeth K. and El Khoury, Joseph B.}, title = {{Microglial Dysfunction and Defective β-Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice}}, journal = {Journal of Neuroscience}, year = {2008}, doi = {10.1523/jneurosci.0616-08.2008}, pmid = {18701698}, url = {https://doi.org/10.1523/jneurosci.0616-08.2008} } @article{buckner2008-18400922, author = {Buckner, Randy Lee and Andrews‐Hanna, Jessica R. and Schacter, Daniel L.}, title = {{The brain's default network: anatomy, function, and relevance to disease}}, journal = {Annals of the New York Academy of Sciences}, year = {2008}, doi = {10.1196/annals.1440.011}, pmid = {18400922}, url = {https://doi.org/10.1196/annals.1440.011} } @article{tanzi1988-2893290, author = {Tanzi, Rudolph E. and McClatchey, Andrea I. and Lamperti, Edward D. and Villa‐Komaroff, Lydia and Gusella, James F. and Neve, Rachael L.}, title = {{Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease}}, journal = {Nature}, year = {1988}, doi = {10.1038/331528a0}, pmid = {2893290}, url = {https://doi.org/10.1038/331528a0} } @article{kurniansyah2026-42661068, author = {Kurniansyah, N. and Tasaki, S. and Rehman, H. and Zhu, C. and Farrell, J. and Sherva, R. and Hauger, R. and Merritt, V. C. and Panizzon, M. and Zhang, R. and Gaziano, J. M. and Gim, J. and others}, title = {{A multiancestry polygenic risk score for Alzheimer's disease is associated with cognitive decline and neuropathological hallmarks in diverse populations}}, journal = {Nature genetics}, year = {2026}, doi = {10.1038/s41588-026-02722-8}, pmid = {42661068}, url = {https://doi.org/10.1038/s41588-026-02722-8} } @article{therriault2024-38429551, author = {Therriault, J. and Schindler, S. E. and Salvadó, G. and Pascoal, T. A. and Benedet, A. L. and Ashton, N. J. and Karikari, T. K. and Apostolova, L. and others}, title = {{Biomarker-based staging of Alzheimer disease: rationale and clinical applications}}, journal = {Nature reviews. Neurology}, year = {2024}, doi = {10.1038/s41582-024-00942-2}, pmid = {38429551}, url = {https://doi.org/10.1038/s41582-024-00942-2} } @article{lam2024-39331846, author = {Lam, A. D. and Thibault, E. G. and Mayblyum, D. V. and Hsieh, S. and Pellerin, K. R. and Sternberg, E. J. and Viswanathan, A. and Buss, S. and others}, title = {{Association of Seizure Foci and Location of Tau and Amyloid Deposition and Brain Atrophy in Patients With Alzheimer Disease and Seizures}}, journal = {Neurology}, year = {2024}, doi = {10.1212/wnl.0000000000209920}, pmid = {39331846}, url = {https://doi.org/10.1212/wnl.0000000000209920} } @article{blacker1998-9697696, author = {Blacker, D. and Wilcox, M. A. and Laird, N. M. and Rodes, L. and Horvath, S. M. and Go, R. C. and Perry, R. and Watson, B. and others}, title = {{Alpha-2 macroglobulin is genetically associated with Alzheimer disease}}, journal = {Nature genetics}, year = {1998}, doi = {10.1038/1243}, pmid = {9697696}, url = {https://doi.org/10.1038/1243} } @article{brase2023-37085492, author = {Brase, L. and You, S. F. and D'Oliveira Albanus, R. and Del-Aguila, J. L. and Dai, Y. and Novotny, B. C. and Soriano-Tarraga, C. and Dykstra, T. and others}, title = {{Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers}}, journal = {Nature communications}, year = {2023}, doi = {10.1038/s41467-023-37437-5}, pmid = {37085492}, url = {https://doi.org/10.1038/s41467-023-37437-5} } @article{sano1996-8876776, author = {Sano, M. and Ernesto, C. and Klauber, M. R. and Schafer, K. and Woodbury, P. and Thomas, R. and Grundman, M. and Growdon, J. and others}, title = {{Rationale and design of a multicenter study of selegiline and alpha-tocopherol in the treatment of Alzheimer disease using novel clinical outcomes. Alzheimer's Disease Cooperative Study}}, journal = {Alzheimer disease and associated disorders}, year = {1996}, doi = {10.1097/00002093-199601030-00004}, pmid = {8876776}, url = {https://doi.org/10.1097/00002093-199601030-00004} } @article{grill2024-38585443, author = {Grill, J. D. and Raman, R. and Ernstrom, K. and Wang, S. and Donohue, M. C. and Aisen, P. S. and Karlawish, J. and Henley, D. and others}, title = {{Immediate Reactions to Alzheimer Biomarker Disclosure in Cognitively Unimpaired Individuals in a Global Truncated Randomized Trial}}, journal = {Neurology. Clinical practice}, year = {2024}, doi = {10.1212/cpj.0000000000200265}, pmid = {38585443}, url = {https://doi.org/10.1212/cpj.0000000000200265} } @article{mcmanus2022-35220356, author = {McManus, K. R. and Lapid, M. I. and Forester, B. P. and Mueller, M. and Hermida, A. P. and Nykamp, L. and Harper, D. G. and Seiner, S. J. and others}, title = {{Simulated Electroconvulsive Therapy: A Novel Approach to a Control Group in Clinical Trials}}, journal = {The journal of ECT}, year = {2022}, doi = {10.1097/yct.0000000000000832}, pmid = {35220356}, url = {https://doi.org/10.1097/yct.0000000000000832} } @article{sperling2014-24648338, author = {Sperling, R. A. and Rentz, D. M. and Johnson, K. A. and Karlawish, J. and Donohue, M. and Salmon, D. P. and Aisen, P.}, title = {{The A4 study: stopping AD before symptoms begin?}}, journal = {Science translational medicine}, year = {2014}, doi = {10.1126/scitranslmed.3007941}, pmid = {24648338}, url = {https://doi.org/10.1126/scitranslmed.3007941} } @article{fong2015-26139023, author = {Fong, T. G. and Davis, D. and Growdon, M. E. and Albuquerque, A. and Inouye, S. K.}, title = {{The interface between delirium and dementia in elderly adults}}, journal = {The Lancet. Neurology}, year = {2015}, doi = {10.1016/s1474-4422(15)00101-5}, pmid = {26139023}, url = {https://doi.org/10.1016/s1474-4422(15)00101-5} } @article{sachdev2014-25266297, author = {Sachdev, P. S. and Blacker, D. and Blazer, D. G. and Ganguli, M. and Jeste, D. V. and Paulsen, J. S. and Petersen, R. C.}, title = {{Classifying neurocognitive disorders: the DSM-5 approach}}, journal = {Nature reviews. Neurology}, year = {2014}, doi = {10.1038/nrneurol.2014.181}, pmid = {25266297}, url = {https://doi.org/10.1038/nrneurol.2014.181} } @article{kaufmann2017-28093795, author = {Kaufmann, H. and Norcliffe-Kaufmann, L. and Palma, J. A. and Biaggioni, I. and Low, P. A. and Singer, W. and Goldstein, D. S. and Peltier, A. C. and others}, title = {{Natural history of pure autonomic failure: A United States prospective cohort}}, journal = {Annals of neurology}, year = {2017}, doi = {10.1002/ana.24877}, pmid = {28093795}, url = {https://doi.org/10.1002/ana.24877} } @article{jefferson2007-17389308, author = {Jefferson, A. L. and Massaro, J. M. and Wolf, P. A. and Seshadri, S. and Au, R. and Vasan, R. S. and Larson, M. G. and Meigs, J. B. and others}, title = {{Inflammatory biomarkers are associated with total brain volume: the Framingham Heart Study}}, journal = {Neurology}, year = {2007}, doi = {10.1212/01.wnl.0000257815.20548.df}, pmid = {17389308}, url = {https://doi.org/10.1212/01.wnl.0000257815.20548.df} } @article{fleisher2013-22633529, author = {Fleisher, A. S. and Chen, K. and Liu, X. and Ayutyanont, N. and Roontiva, A. and Thiyyagura, P. and Protas, H. and Joshi, A. D. and others}, title = {{Apolipoprotein E ε4 and age effects on florbetapir positron emission tomography in healthy aging and Alzheimer disease}}, journal = {Neurobiology of aging}, year = {2013}, doi = {10.1016/j.neurobiolaging.2012.04.017}, pmid = {22633529}, url = {https://doi.org/10.1016/j.neurobiolaging.2012.04.017} } @article{rentz2021-33589537, author = {Rentz, D. M. and Papp, K. V. and Mayblyum, D. V. and Sanchez, J. S. and Klein, H. and Souillard-Mandar, W. and Sperling, R. A. and Johnson, K. A.}, title = {{Association of Digital Clock Drawing With PET Amyloid and Tau Pathology in Normal Older Adults}}, journal = {Neurology}, year = {2021}, doi = {10.1212/wnl.0000000000011697}, pmid = {33589537}, url = {https://doi.org/10.1212/wnl.0000000000011697} } @article{burberry2020-32483373, author = {Burberry, A. and Wells, M. F. and Limone, F. and Couto, A. and Smith, K. S. and Keaney, J. and Gillet, G. and van Gastel, N. and others}, title = {{C9orf72 suppresses systemic and neural inflammation induced by gut bacteria}}, journal = {Nature}, year = {2020}, doi = {10.1038/s41586-020-2288-7}, pmid = {32483373}, url = {https://doi.org/10.1038/s41586-020-2288-7} } @article{power2018-29944741, author = {Power, M. C. and Mormino, E. and Soldan, A. and James, B. D. and Yu, L. and Armstrong, N. M. and Bangen, K. J. and Delano-Wood, L. and others}, title = {{Combined neuropathological pathways account for age-related risk of dementia}}, journal = {Annals of neurology}, year = {2018}, doi = {10.1002/ana.25246}, pmid = {29944741}, url = {https://doi.org/10.1002/ana.25246} } @article{parra2021-33634602, author = {Parra, M. A. and Baez, S. and Sedeño, L. and Gonzalez Campo, C. and Santamaría-García, H. and Aprahamian, I. and Bertolucci, P. H. and Bustin, J. and others}, title = {{Dementia in Latin America: Paving the way toward a regional action plan}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2021}, doi = {10.1002/alz.12202}, pmid = {33634602}, url = {https://doi.org/10.1002/alz.12202} } @article{antonarakis2020-32029743, author = {Antonarakis, S. E. and Skotko, B. G. and Rafii, M. S. and Strydom, A. and Pape, S. E. and Bianchi, D. W. and Sherman, S. L. and Reeves, R. H.}, title = {{Down syndrome}}, journal = {Nature reviews. Disease primers}, year = {2020}, doi = {10.1038/s41572-019-0143-7}, pmid = {32029743}, url = {https://doi.org/10.1038/s41572-019-0143-7} } @article{birba2022-35491275, author = {Birba, A. and Santamaría-García, H. and Prado, P. and Cruzat, J. and Ballesteros, A. S. and Legaz, A. and Fittipaldi, S. and Duran-Aniotz, C. and others}, title = {{Allostatic-Interoceptive Overload in Frontotemporal Dementia}}, journal = {Biological psychiatry}, year = {2022}, doi = {10.1016/j.biopsych.2022.02.955}, pmid = {35491275}, url = {https://doi.org/10.1016/j.biopsych.2022.02.955} } @article{zammit2026-41240365, author = {Zammit, M. D. and Bruzzone, H. and Cody, K. A. and Morse, J. and Wilson, R. and Bettcher, B. T. and McLachlan, M. J. and McVea, A. K. and others}, title = {{The tau biomarker cascade is condensed in Down syndrome compared with sporadic Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2026}, doi = {10.1093/brain/awaf428}, pmid = {41240365}, url = {https://doi.org/10.1093/brain/awaf428} } @article{xicota2024-39500037, author = {Xicota, L. and Dang, L. T. and Lee, A. and Krinsky-McHale, S. and Pang, D. and Melilli, L. and O'Bryant, S. and Henson, R. L. and others}, title = {{The effects of mosaicism on biological and clinical markers of Alzheimer's disease in adults with Down syndrome}}, journal = {EBioMedicine}, year = {2024}, doi = {10.1016/j.ebiom.2024.105433}, pmid = {39500037}, url = {https://doi.org/10.1016/j.ebiom.2024.105433} } @article{decalignon2010-20357768, author = {de Calignon, A. and Fox, L. M. and Pitstick, R. and Carlson, G. A. and Bacskai, B. J. and Spires-Jones, T. L. and Hyman, B. T.}, title = {{Caspase activation precedes and leads to tangles}}, journal = {Nature}, year = {2010}, doi = {10.1038/nature08890}, pmid = {20357768}, url = {https://doi.org/10.1038/nature08890} } @article{mazaheri2017-28483841, author = {Mazaheri, F. and Snaidero, N. and Kleinberger, G. and Madore, C. and Daria, A. and Werner, G. and Krasemann, S. and Capell, A. and others}, title = {{TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury}}, journal = {EMBO reports}, year = {2017}, doi = {10.15252/embr.201743922}, pmid = {28483841}, url = {https://doi.org/10.15252/embr.201743922} } @article{donovan2014-24698445, author = {Donovan, N. J. and Amariglio, R. E. and Zoller, A. S. and Rudel, R. K. and Gomez-Isla, T. and Blacker, D. and Hyman, B. T. and Locascio, J. J. and others}, title = {{Subjective cognitive concerns and neuropsychiatric predictors of progression to the early clinical stages of Alzheimer disease}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2014}, doi = {10.1016/j.jagp.2014.02.007}, pmid = {24698445}, url = {https://doi.org/10.1016/j.jagp.2014.02.007} } @article{fleisher2015-25580592, author = {Fleisher, A. S. and Chen, K. and Quiroz, Y. T. and Jakimovich, L. J. and Gutierrez Gomez, M. and Langois, C. M. and Langbaum, J. B. and Roontiva, A. and others}, title = {{Associations between biomarkers and age in the presenilin 1 E280A autosomal dominant Alzheimer disease kindred: a cross-sectional study}}, journal = {JAMA neurology}, year = {2015}, doi = {10.1001/jamaneurol.2014.3314}, pmid = {25580592}, url = {https://doi.org/10.1001/jamaneurol.2014.3314} } @article{griciuc2019-31301936, author = {Griciuc, A. and Patel, S. and Federico, A. N. and Choi, S. H. and Innes, B. J. and Oram, M. K. and Cereghetti, G. and McGinty, D. and others}, title = {{TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer's Disease}}, journal = {Neuron}, year = {2019}, doi = {10.1016/j.neuron.2019.06.010}, pmid = {31301936}, url = {https://doi.org/10.1016/j.neuron.2019.06.010} } @article{schindler2019-30846386, author = {Schindler, S. E. and Li, Y. and Todd, K. W. and Herries, E. M. and Henson, R. L. and Gray, J. D. and Wang, G. and Graham, D. L. and others}, title = {{Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2019}, doi = {10.1016/j.jalz.2018.12.019}, pmid = {30846386}, url = {https://doi.org/10.1016/j.jalz.2018.12.019} } @article{donovan2014-23890751, author = {Donovan, N. J. and Wadsworth, L. P. and Lorius, N. and Locascio, J. J. and Rentz, D. M. and Johnson, K. A. and Sperling, R. A. and Marshall, G. A. and others}, title = {{Regional cortical thinning predicts worsening apathy and hallucinations across the Alzheimer disease spectrum}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2014}, doi = {10.1016/j.jagp.2013.03.006}, pmid = {23890751}, url = {https://doi.org/10.1016/j.jagp.2013.03.006} } @article{doraiswamy2014-24614494, author = {Doraiswamy, P. M. and Sperling, R. A. and Johnson, K. and Reiman, E. M. and Wong, T. Z. and Sabbagh, M. N. and Sadowsky, C. H. and Fleisher, A. S. and others}, title = {{Florbetapir F 18 amyloid PET and 36-month cognitive decline: a prospective multicenter study}}, journal = {Molecular psychiatry}, year = {2014}, doi = {10.1038/mp.2014.9}, pmid = {24614494}, url = {https://doi.org/10.1038/mp.2014.9} } @article{pase2017-28835407, author = {Pase, M. P. and Himali, J. J. and Grima, N. A. and Beiser, A. S. and Satizabal, C. L. and Aparicio, H. J. and Thomas, R. J. and Gottlieb, D. J. and others}, title = {{Sleep architecture and the risk of incident dementia in the community}}, journal = {Neurology}, year = {2017}, doi = {10.1212/wnl.0000000000004373}, pmid = {28835407}, url = {https://doi.org/10.1212/wnl.0000000000004373} } @article{peloso2020-32690788, author = {Peloso, G. M. and Beiser, A. S. and Satizabal, C. L. and Xanthakis, V. and Vasan, R. S. and Pase, M. P. and Destefano, A. L. and Seshadri, S.}, title = {{Cardiovascular health, genetic risk, and risk of dementia in the Framingham Heart Study}}, journal = {Neurology}, year = {2020}, doi = {10.1212/wnl.0000000000010306}, pmid = {32690788}, url = {https://doi.org/10.1212/wnl.0000000000010306} } @article{gao2023-36808743, author = {Gao, L. and Li, P. and Gaykova, N. and Zheng, X. and Gao, C. and Lane, J. M. and Saxena, R. and Scheer, F. A. J. L. and others}, title = {{Circadian Rest-Activity Rhythms, Delirium Risk, and Progression to Dementia}}, journal = {Annals of neurology}, year = {2023}, doi = {10.1002/ana.26617}, pmid = {36808743}, url = {https://doi.org/10.1002/ana.26617} } @article{he1997-9024664, author = {He, J. and Chen, Y. and Farzan, M. and Choe, H. and Ohagen, A. and Gartner, S. and Busciglio, J. and Yang, X. and others}, title = {{CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia}}, journal = {Nature}, year = {1997}, doi = {10.1038/385645a0}, pmid = {9024664}, url = {https://doi.org/10.1038/385645a0} } @article{kuchibhotla2009-19251629, author = {Kuchibhotla, K. V. and Lattarulo, C. R. and Hyman, B. T. and Bacskai, B. J.}, title = {{Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice}}, journal = {Science (New York, N.Y.)}, year = {2009}, doi = {10.1126/science.1169096}, pmid = {19251629}, url = {https://doi.org/10.1126/science.1169096} } @article{roy2020-31917687, author = {Roy, E. R. and Wang, B. and Wan, Y. W. and Chiu, G. and Cole, A. and Yin, Z. and Propson, N. E. and Xu, Y. and others}, title = {{Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease}}, journal = {The Journal of clinical investigation}, year = {2020}, doi = {10.1172/jci133737}, pmid = {31917687}, url = {https://doi.org/10.1172/jci133737} } @article{bairamian2022-35248147, author = {Bairamian, D. and Sha, S. and Rolhion, N. and Sokol, H. and Dorothée, G. and Lemere, C. A. and Krantic, S.}, title = {{Microbiota in neuroinflammation and synaptic dysfunction: a focus on Alzheimer's disease}}, journal = {Molecular neurodegeneration}, year = {2022}, doi = {10.1186/s13024-022-00522-2}, pmid = {35248147}, url = {https://doi.org/10.1186/s13024-022-00522-2} } @article{rohatgi2025-41038644, author = {Rohatgi, Saurabh and Zhu, Shenghua and Calle, Esteban and Ford, Jeremy N. and Kozak, Benjamin M. and Chagui, Odette Ganem and Vejdani‐Jahromi, Maryam and Griffin, Harry R. and others}, title = {{Are Deep White Matter Hyperintensities Associated with Amyloid-Related Imaging Abnormalities in Patients with Alzheimer Disease Treated with Lecanemab?}}, journal = {American Journal of Neuroradiology}, year = {2025}, doi = {10.3174/ajnr.a8822}, pmid = {41038644}, url = {https://doi.org/10.3174/ajnr.a8822} } @article{francis2025-40824575, author = {Francis, Lily and Seshadri, Sudha S. and Dillard, Lauren K. and Kujawa, Sharon G. and Welling, D. Bradley and Alcabes, Richard L. and Beiser, Alexa S.}, title = {{Self-Reported Hearing Aid Use and Risk of Incident Dementia}}, journal = {JAMA Neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.2713}, pmid = {40824575}, url = {https://doi.org/10.1001/jamaneurol.2025.2713} } @article{aaronson2025-40249614, author = {Aaronson, Anna and Diaz, Adam and Ashford, Miriam Thiel and Jin, Chengshi and Tank, Rachana and Miller, Melanie Jayne and Kang, Jae Myeong and Manjavong, Manchumad and others}, title = {{Self- and Informant-Report Cognitive Decline Discordance and Mild Cognitive Impairment Diagnosis}}, journal = {JAMA Network Open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.5810}, pmid = {40249614}, url = {https://doi.org/10.1001/jamanetworkopen.2025.5810} } @article{brycesmith2025-41120751, author = {Bryce-Smith, Sam and Brown, Anna‐Leigh and Chien, Max Z. Y. J. and Dattilo, Dario and Mehta, Puja R. and Mattedi, Francesca and Barattucci, Simone and Mikheenko, Alla and others}, title = {{TDP-43 loss induces cryptic polyadenylation in ALS/FTD}}, journal = {Nature Neuroscience}, year = {2025}, doi = {10.1038/s41593-025-02050-w}, pmid = {41120751}, url = {https://doi.org/10.1038/s41593-025-02050-w} } @article{chen2025-40531522, author = {Chen, Hui and Ding, Yihong and Dhana, Klodian and Agarwal, Puja and Beck, Todd L. and Rajan, Kumar Bharat and van Lent, Debora Melo and Ma, Yuan and others}, title = {{Sweetened Beverages and Incident All-Cause Dementia Among Older Adults}}, journal = {JAMA Psychiatry}, year = {2025}, doi = {10.1001/jamapsychiatry.2025.1230}, pmid = {40531522}, url = {https://doi.org/10.1001/jamapsychiatry.2025.1230} } @article{morris2015-25681666, author = {Morris, Martha Clare and Tangney, Christy and Wang, Yamin and Sacks, Frank M. and Bennett, David A. and Aggarwal, Neelum T.}, title = {{MIND diet associated with reduced incidence of Alzheimer's disease}}, journal = {Alzheimer s \& Dementia}, year = {2015}, doi = {10.1016/j.jalz.2014.11.009}, pmid = {25681666}, url = {https://doi.org/10.1016/j.jalz.2014.11.009} } @article{farris2003-12634421, author = {Farris, Wesley and Mansourian, Stefan and Chang, Yang and Lindsley, Loren D. and Eckman, Elizabeth A. and Frosch, Matthew P. and Eckman, Christopher B. and Tanzi, Rudolph E. and Selkoe, Dennis J. and Guénette, Suzanne Y.}, title = {{Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain in vivo}}, journal = {Proceedings of the National Academy of Sciences}, year = {2003}, doi = {10.1073/pnas.0230450100}, pmid = {12634421}, url = {https://doi.org/10.1073/pnas.0230450100} } @article{johnson2013-23360977, author = {Johnson, K. A. and Minoshima, S. and Bohnen, N. I. and Donohoe, K. J. and Foster, N. L. and Herscovitch, P. and Karlawish, J. H. and Rowe, C. C. and others}, title = {{Appropriate use criteria for amyloid PET: a report of the Amyloid Imaging Task Force, the Society of Nuclear Medicine and Molecular Imaging, and the Alzheimer's Association}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2013}, doi = {10.1016/j.jalz.2013.01.002}, pmid = {23360977}, url = {https://doi.org/10.1016/j.jalz.2013.01.002} } @article{quiroz2015-26121081, author = {Quiroz, Y. T. and Schultz, A. P. and Chen, K. and Protas, H. D. and Brickhouse, M. and Fleisher, A. S. and Langbaum, J. B. and Thiyyagura, P. and others}, title = {{Brain Imaging and Blood Biomarker Abnormalities in Children With Autosomal Dominant Alzheimer Disease: A Cross-Sectional Study}}, journal = {JAMA neurology}, year = {2015}, doi = {10.1001/jamaneurol.2015.1099}, pmid = {26121081}, url = {https://doi.org/10.1001/jamaneurol.2015.1099} } @article{schoemaker2021-33627498, author = {Schoemaker, D. and Charidimou, A. and Zanon Zotin, M. C. and Raposo, N. and Johnson, K. A. and Sanchez, J. S. and Greenberg, S. M. and Viswanathan, A.}, title = {{Association of Memory Impairment With Concomitant Tau Pathology in Patients With Cerebral Amyloid Angiopathy}}, journal = {Neurology}, year = {2021}, doi = {10.1212/wnl.0000000000011745}, pmid = {33627498}, url = {https://doi.org/10.1212/wnl.0000000000011745} } @article{tan2003-12742802, author = {Tan, Z. S. and Seshadri, S. and Beiser, A. and Wilson, P. W. and Kiel, D. P. and Tocco, M. and D'Agostino, R. B. and Wolf, P. A.}, title = {{Plasma total cholesterol level as a risk factor for Alzheimer disease: the Framingham Study}}, journal = {Archives of internal medicine}, year = {2003}, doi = {10.1001/archinte.163.9.1053}, pmid = {12742802}, url = {https://doi.org/10.1001/archinte.163.9.1053} } @article{serranopozo2015-25623662, author = {Serrano-Pozo, A. and Qian, J. and Monsell, S. E. and Betensky, R. A. and Hyman, B. T.}, title = {{APOEε2 is associated with milder clinical and pathological Alzheimer disease}}, journal = {Annals of neurology}, year = {2015}, doi = {10.1002/ana.24369}, pmid = {25623662}, url = {https://doi.org/10.1002/ana.24369} } @article{growdon2015-25934852, author = {Growdon, M. E. and Schultz, A. P. and Dagley, A. S. and Amariglio, R. E. and Hedden, T. and Rentz, D. M. and Johnson, K. A. and Sperling, R. A. and others}, title = {{Odor identification and Alzheimer disease biomarkers in clinically normal elderly}}, journal = {Neurology}, year = {2015}, doi = {10.1212/wnl.0000000000001614}, pmid = {25934852}, url = {https://doi.org/10.1212/wnl.0000000000001614} } @article{lai1999-10430422, author = {Lai, F. and Kammann, E. and Rebeck, G. W. and Anderson, A. and Chen, Y. and Nixon, R. A.}, title = {{APOE genotype and gender effects on Alzheimer disease in 100 adults with Down syndrome}}, journal = {Neurology}, year = {1999}, doi = {10.1212/wnl.53.2.331}, pmid = {10430422}, url = {https://doi.org/10.1212/wnl.53.2.331} } @article{mielke2022-35394117, author = {Mielke, M. M. and Aggarwal, N. T. and Vila-Castelar, C. and Agarwal, P. and Arenaza-Urquijo, E. M. and Brett, B. and Brugulat-Serrat, A. and DuBose, L. E. and others}, title = {{Consideration of sex and gender in Alzheimer's disease and related disorders from a global perspective}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2022}, doi = {10.1002/alz.12662}, pmid = {35394117}, url = {https://doi.org/10.1002/alz.12662} } @article{kimberly2009-19349602, author = {Kimberly, W. T. and Gilson, A. and Rost, N. S. and Rosand, J. and Viswanathan, A. and Smith, E. E. and Greenberg, S. M.}, title = {{Silent ischemic infarcts are associated with hemorrhage burden in cerebral amyloid angiopathy}}, journal = {Neurology}, year = {2009}, doi = {10.1212/01.wnl.0000345666.83318.03}, pmid = {19349602}, url = {https://doi.org/10.1212/01.wnl.0000345666.83318.03} } @article{pereznievas2013-23824488, author = {Perez-Nievas, B. G. and Stein, T. D. and Tai, H. C. and Dols-Icardo, O. and Scotton, T. C. and Barroeta-Espar, I. and Fernandez-Carballo, L. and de Munain, E. L. and others}, title = {{Dissecting phenotypic traits linked to human resilience to Alzheimer's pathology}}, journal = {Brain : a journal of neurology}, year = {2013}, doi = {10.1093/brain/awt171}, pmid = {23824488}, url = {https://doi.org/10.1093/brain/awt171} } @article{gomperts2016-27654968, author = {Gomperts, S. N. and Locascio, J. J. and Makaretz, S. J. and Schultz, A. and Caso, C. and Vasdev, N. and Sperling, R. and Growdon, J. H. and others}, title = {{Tau Positron Emission Tomographic Imaging in the Lewy Body Diseases}}, journal = {JAMA neurology}, year = {2016}, doi = {10.1001/jamaneurol.2016.3338}, pmid = {27654968}, url = {https://doi.org/10.1001/jamaneurol.2016.3338} } @article{schraufnagel2019-30419237, author = {Schraufnagel, D. E. and Balmes, JR. and Cowl, C. T. and De Matteis, S. and Jung, S. H. and Mortimer, K. and Perez-Padilla, R. and Rice, M. B. and others}, title = {{Air Pollution and Noncommunicable Diseases: A Review by the Forum of International Respiratory Societies' Environmental Committee, Part 2: Air Pollution and Organ Systems}}, journal = {Chest}, year = {2019}, doi = {10.1016/j.chest.2018.10.041}, pmid = {30419237}, url = {https://doi.org/10.1016/j.chest.2018.10.041} }