% alzhub.org library filter % Source: https://alzhub.org/research?institution=I111088046 % 389 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{chatterjee2016-26681727, author = {Chatterjee, S. and Peters, S. A. and Woodward, M. and Mejia Arango, S. and Batty, G. D. and Beckett, N. and Beiser, A. and Borenstein, A. R. and others}, title = {{Type 2 Diabetes as a Risk Factor for Dementia in Women Compared With Men: A Pooled Analysis of 2.3 Million People Comprising More Than 100,000 Cases of Dementia}}, journal = {Diabetes care}, year = {2016}, doi = {10.2337/dc15-1588}, pmid = {26681727}, url = {https://doi.org/10.2337/dc15-1588} } @article{kunkle2019-30820047, author = {Kunkle, B. W. and Grenier-Boley, B. and Sims, R. and Bis, J. C. and Damotte, V. and Naj, A. C. and Boland, A. and Vronskaya, M. and others}, title = {{Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing}}, journal = {Nature genetics}, year = {2019}, doi = {10.1038/s41588-019-0358-2}, pmid = {30820047}, url = {https://doi.org/10.1038/s41588-019-0358-2} } @article{belloy2023-37930705, author = {Belloy, M. E. and Andrews, S. J. and Le Guen, Y. and Cuccaro, M. and Farrer, L. A. and Napolioni, V. and Greicius, M. D.}, title = {{APOE Genotype and Alzheimer Disease Risk Across Age, Sex, and Population Ancestry}}, journal = {JAMA Neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.3599}, pmid = {37930705}, url = {https://doi.org/10.1001/jamaneurol.2023.3599} } @article{naj2011-21460841, author = {Naj, A. C. and Jun, G. and Beecham, G. W. and Wang, L. S. and Vardarajan, B. N. and Buros, J. and Gallins, P. J. and Buxbaum, J. D. and others}, title = {{Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease}}, journal = {Nature genetics}, year = {2011}, doi = {10.1038/ng.801}, pmid = {21460841}, url = {https://doi.org/10.1038/ng.801} } @article{wolters2020-32611641, author = {Wolters, F. J. and Chibnik, L. B. and Waziry, R. and Anderson, R. and Berr, C. and Beiser, A. and Bis, J. C. and Blacker, D. and others}, title = {{Twenty-seven-year time trends in dementia incidence in Europe and the United States: The Alzheimer Cohorts Consortium}}, journal = {Neurology}, year = {2020}, doi = {10.1212/wnl.0000000000010022}, pmid = {32611641}, url = {https://doi.org/10.1212/wnl.0000000000010022} } @article{sims2017-28714976, author = {Sims, R. and van der Lee, S. J. and Naj, A. C. and Bellenguez, C. and Badarinarayan, N. and Jakobsdottir, J. and Kunkle, B. W. and Boland, A. and others}, title = {{Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease}}, journal = {Nature genetics}, year = {2017}, doi = {10.1038/ng.3916}, pmid = {28714976}, url = {https://doi.org/10.1038/ng.3916} } @article{chen2023-37133875, author = {Chen, H. and Dhana, K. and Huang, Y. and Huang, L. and Tao, Y. and Liu, X. and others}, title = {{Association of the Mediterranean Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diet With the Risk of Dementia}}, journal = {JAMA Psychiatry}, year = {2023}, doi = {10.1001/jamapsychiatry.2023.0800}, pmid = {37133875}, url = {https://doi.org/10.1001/jamapsychiatry.2023.0800} } @article{green2009-20009055, author = {Green, R. C. and Schneider, L. S. and Amato, D. A. and Beelen, A. P. and Wilcock, G. and Swabb, E. A. and Zavitz, K. H. and {Tarenflurbil Phase 3 Study Group}}, title = {{Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: a randomized controlled trial}}, journal = {JAMA}, year = {2009}, doi = {10.1001/jama.2009.1866}, pmid = {20009055}, url = {https://doi.org/10.1001/jama.2009.1866} } @article{pase2023-37462968, author = {Pase, M. P. and Harrison, S. and Misialek, JR. and Kline, C. E. and Cavuoto, M. and Baril, A. A. and Yiallourou, S. and Bisson, A. and others}, title = {{Sleep Architecture, Obstructive Sleep Apnea, and Cognitive Function in Adults}}, journal = {JAMA network open}, year = {2023}, doi = {10.1001/jamanetworkopen.2023.25152}, pmid = {37462968}, url = {https://doi.org/10.1001/jamanetworkopen.2023.25152} } @article{bouzid2023-37322115, author = {Bouzid, H. and Belk, J. A. and Jan, M. and Qi, Y. and Sarnowski, C. and Wirth, S. and Ma, L. and Chrostek, M. R. and others}, title = {{Clonal hematopoiesis is associated with protection from Alzheimer's disease}}, journal = {Nature medicine}, year = {2023}, doi = {10.1038/s41591-023-02397-2}, pmid = {37322115}, url = {https://doi.org/10.1038/s41591-023-02397-2} } @article{jun2016-25778476, author = {Jun, G. and Ibrahim-Verbaas, C. A. and Vronskaya, M. and Lambert, J. C. and Chung, J. and Naj, A. C. and Kunkle, B. W. and Wang, L. S. and others}, title = {{A novel Alzheimer disease locus located near the gene encoding tau protein}}, journal = {Molecular psychiatry}, year = {2016}, doi = {10.1038/mp.2015.23}, pmid = {25778476}, url = {https://doi.org/10.1038/mp.2015.23} } @article{seshadri2010-20460622, author = {Seshadri, S. and Fitzpatrick, A. L. and Ikram, M. A. and DeStefano, A. L. and Gudnason, V. and Boada, M. and Bis, J. C. and Smith, A. V. and others}, title = {{Genome-wide analysis of genetic loci associated with Alzheimer disease}}, journal = {JAMA}, year = {2010}, doi = {10.1001/jama.2010.574}, pmid = {20460622}, url = {https://doi.org/10.1001/jama.2010.574} } @article{reitz2013-23571587, author = {Reitz, C. and Jun, G. and Naj, A. and Rajbhandary, R. and Vardarajan, B. N. and Wang, L. S. and Valladares, O. and Lin, C. F. and others}, title = {{Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans}}, journal = {JAMA}, year = {2013}, doi = {10.1001/jama.2013.2973}, pmid = {23571587}, url = {https://doi.org/10.1001/jama.2013.2973} } @article{kunkle2021-33074286, author = {Kunkle, B. W. and Schmidt, M. and Klein, H. U. and Naj, A. C. and Hamilton-Nelson, K. L. and Larson, E. B. and Evans, D. A. and De Jager, P. L. and others}, title = {{Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis}}, journal = {JAMA neurology}, year = {2021}, doi = {10.1001/jamaneurol.2020.3536}, pmid = {33074286}, url = {https://doi.org/10.1001/jamaneurol.2020.3536} } @article{wessels2020-31764959, author = {Wessels, A. M. and Tariot, P. N. and Zimmer, J. A. and Selzler, K. J. and Bragg, S. M. and Andersen, S. W. and Landry, J. and Krull, J. H. and others}, title = {{Efficacy and Safety of Lanabecestat for Treatment of Early and Mild Alzheimer Disease: The AMARANTH and DAYBREAK-ALZ Randomized Clinical Trials}}, journal = {JAMA neurology}, year = {2020}, doi = {10.1001/jamaneurol.2019.3988}, pmid = {31764959}, url = {https://doi.org/10.1001/jamaneurol.2019.3988} } @article{rajabli2025-40676597, author = {Rajabli, F. and Benchek, P. and Tosto, G. and Kushch, N. and Sha, J. and Bazemore, K. and Zhu, C. and Lee, W. P. and others}, title = {{Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease}}, journal = {Genome biology}, year = {2025}, doi = {10.1186/s13059-025-03564-z}, pmid = {40676597}, url = {https://doi.org/10.1186/s13059-025-03564-z} } @article{fornage2011-21681796, author = {Fornage, M. and Debette, S. and Bis, J. C. and Schmidt, H. and Ikram, M. A. and Dufouil, C. and Sigurdsson, S. and Lumley, T. and others}, title = {{Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium}}, journal = {Annals of neurology}, year = {2011}, doi = {10.1002/ana.22403}, pmid = {21681796}, url = {https://doi.org/10.1002/ana.22403} } @article{sherva2023-36543923, author = {Sherva, R. and Zhang, R. and Sahelijo, N. and Jun, G. and Anglin, T. and Chanfreau, C. and Cho, K. and Fonda, JR. and others}, title = {{African ancestry GWAS of dementia in a large military cohort identifies significant risk loci}}, journal = {Molecular psychiatry}, year = {2023}, doi = {10.1038/s41380-022-01890-3}, pmid = {36543923}, url = {https://doi.org/10.1038/s41380-022-01890-3} } @article{neu2017-28846757, author = {Neu, S. C. and Pa, J. and Kukull, W. and Beekly, D. and Kuzma, A. and Gangadharan, P. and Wang, L. S. and Romero, K. and others}, title = {{Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis}}, journal = {JAMA neurology}, year = {2017}, doi = {10.1001/jamaneurol.2017.2188}, pmid = {28846757}, url = {https://doi.org/10.1001/jamaneurol.2017.2188} } @article{sims2023-37459141, author = {Sims, JR. and Zimmer, J. A. and Evans, C. D. and Lu, M. and Ardayfio, P. and Sparks, J. and Wessels, A. M. and Shcherbinin, S. and others}, title = {{Donanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial}}, journal = {JAMA}, year = {2023}, doi = {10.1001/jama.2023.13239}, pmid = {37459141}, url = {https://doi.org/10.1001/jama.2023.13239} } @article{ding2020-31706889, author = {Ding, J. and Davis-Plourde, K. L. and Sedaghat, S. and Tully, P. J. and Wang, W. and Phillips, C. and Pase, M. P. and Himali, J. J. and others}, title = {{Antihypertensive medications and risk for incident dementia and Alzheimer's disease: a meta-analysis of individual participant data from prospective cohort studies}}, journal = {The Lancet. Neurology}, year = {2020}, doi = {10.1016/s1474-4422(19)30393-x}, pmid = {31706889}, url = {https://doi.org/10.1016/s1474-4422(19)30393-x} } @article{leguen2023-36809323, author = {Le Guen, Y. and Raulin, A. C. and Logue, M. W. and Sherva, R. and Belloy, M. E. and Eger, S. J. and Chen, A. and Kennedy, G. and Kuchenbecker, L. and O'Leary, J. P. and Zhang, R. and Merritt, V. C. and others}, title = {{Association of African Ancestry-Specific APOE Missense Variant R145C With Risk of Alzheimer Disease}}, journal = {JAMA}, year = {2023}, doi = {10.1001/jama.2023.0268}, pmid = {36809323}, url = {https://doi.org/10.1001/jama.2023.0268} } @article{jansen2022-36066633, author = {Jansen, I. E. and van der Lee, S. J. and Gomez-Fonseca, D. and de Rojas, I. and Dalmasso, M. C. and Grenier-Boley, B. and Zettergren, A. and Mishra, A. and others}, title = {{Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers}}, journal = {Acta neuropathologica}, year = {2022}, doi = {10.1007/s00401-022-02454-z}, pmid = {36066633}, url = {https://doi.org/10.1007/s00401-022-02454-z} } @article{breitner2011-21784351, author = {Breitner, J. C. and Baker, L. D. and Montine, T. J. and Meinert, C. L. and Lyketsos, C. G. and Ashe, K. H. and Brandt, J. and Craft, S. and others}, title = {{Extended results of the Alzheimer's disease anti-inflammatory prevention trial}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2011}, doi = {10.1016/j.jalz.2010.12.014}, pmid = {21784351}, url = {https://doi.org/10.1016/j.jalz.2010.12.014} } @article{li2026-41559019, author = {Li, Joanne M. and Gauen, Abigail and Zmora, Rachel and Stephen, John J. and Petito, Lucia C. and Scholtens, Denise and Peterson, Elizabeth and Kohli-Lynch, Ciaran Navin and others}, title = {{Midlife and late‐life population attributable fractions of risk factors for dementia in the United States: The Dementia Risk Prediction Project}}, journal = {Alzheimer s \& Dementia}, year = {2026}, doi = {10.1002/alz.71065}, pmid = {41559019}, url = {https://doi.org/10.1002/alz.71065} } @article{cronje2023-37392405, author = {Cronjé, H. T. and Liu, X. and Odden, M. C. and Moseholm, K. F. and Seshadri, S. and Satizabal, C. L. and Lopez, O. L. and Bis, J. C. and Djoussé, L. and Fohner, A. E. and Psaty, B. M. and Tracy, R. P. and others}, title = {{Serum NfL and GFAP are associated with incident dementia and dementia mortality in older adults: The cardiovascular health study}}, journal = {Alzheimer's \& Dementia}, year = {2023}, doi = {10.1002/alz.13367}, pmid = {37392405}, url = {https://doi.org/10.1002/alz.13367} } @article{pase2019-30830207, author = {Pase, M. P. and Beiser, A. S. and Himali, J. J. and Satizabal, C. L. and Aparicio, H. J. and DeCarli, C. and Chêne, G. and Dufouil, C. and others}, title = {{Assessment of Plasma Total Tau Level as a Predictive Biomarker for Dementia and Related Endophenotypes}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2018.4666}, pmid = {30830207}, url = {https://doi.org/10.1001/jamaneurol.2018.4666} } @article{naj2014-25199842, author = {Naj, A. C. and Jun, G. and Reitz, C. and Kunkle, B. W. and Perry, W. and Park, Y. S. and Beecham, G. W. and Rajbhandary, R. A. and others}, title = {{Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study}}, journal = {JAMA neurology}, year = {2014}, doi = {10.1001/jamaneurol.2014.1491}, pmid = {25199842}, url = {https://doi.org/10.1001/jamaneurol.2014.1491} } @article{volandes2023-37695586, author = {Volandes, A. E. and Zupanc, S. N. and Lakin, JR. and Cabral, H. J. and Burns, E. A. and Carney, M. T. and Lopez, S. and Itty, J. and others}, title = {{Video Intervention and Goals-of-Care Documentation in Hospitalized Older Adults: The VIDEO-PCE Randomized Clinical Trial}}, journal = {JAMA network open}, year = {2023}, doi = {10.1001/jamanetworkopen.2023.32556}, pmid = {37695586}, url = {https://doi.org/10.1001/jamanetworkopen.2023.32556} } @article{debette2011-21810696, author = {Debette, S. and Seshadri, S. and Beiser, A. and Au, R. and Himali, J. J. and Palumbo, C. and Wolf, P. A. and DeCarli, C.}, title = {{Midlife vascular risk factor exposure accelerates structural brain aging and cognitive decline}}, journal = {Neurology}, year = {2011}, doi = {10.1212/wnl.0b013e318227b227}, pmid = {21810696}, url = {https://doi.org/10.1212/wnl.0b013e318227b227} } @article{nelson2014-24770881, author = {Nelson, P. T. and Estus, S. and Abner, E. L. and Parikh, I. and Malik, M. and Neltner, J. H. and Ighodaro, E. and Wang, W. X. and others}, title = {{ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology}}, journal = {Acta neuropathologica}, year = {2014}, doi = {10.1007/s00401-014-1282-2}, pmid = {24770881}, url = {https://doi.org/10.1007/s00401-014-1282-2} } @article{jack2008-18302232, author = {Jack, Clifford R. and Bernstein, Matt A. and Fox, Nick C. and Thompson, Paul M. and Alexander, Gene E. and Harvey, Danielle Jenine and Borowski, Bret and Britson, Paula J. and others}, title = {{The Alzheimer's disease neuroimaging initiative (ADNI): MRI methods}}, journal = {Journal of Magnetic Resonance Imaging}, year = {2008}, doi = {10.1002/jmri.21049}, pmid = {18302232}, url = {https://doi.org/10.1002/jmri.21049} } @article{xue2024-38965435, author = {Xue, C. and Kowshik, S. S. and Lteif, D. and Puducheri, S. and Jasodanand, V. H. and Zhou, O. T. and Walia, A. S. and Guney, O. B. and others}, title = {{AI-based differential diagnosis of dementia etiologies on multimodal data}}, journal = {Nature medicine}, year = {2024}, doi = {10.1038/s41591-024-03118-z}, pmid = {38965435}, url = {https://doi.org/10.1038/s41591-024-03118-z} } @article{armstrong2020-32517579, author = {Armstrong, N. J. and Mather, K. A. and Sargurupremraj, M. and Knol, M. J. and Malik, R. and Satizabal, C. L. and Yanek, L. R. and Wen, W. and others}, title = {{Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities}}, journal = {Stroke}, year = {2020}, doi = {10.1161/strokeaha.119.027544}, pmid = {32517579}, url = {https://doi.org/10.1161/strokeaha.119.027544} } @article{wolters2019-31356640, author = {Wolters, F. J. and Yang, Q. and Biggs, M. L. and Jakobsdottir, J. and Li, S. and Evans, D. S. and Bis, J. C. and Harris, T. B. and others}, title = {{The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE)}}, journal = {PloS one}, year = {2019}, doi = {10.1371/journal.pone.0219668}, pmid = {31356640}, url = {https://doi.org/10.1371/journal.pone.0219668} } @article{sargurupremraj2020-33293549, author = {Sargurupremraj, M. and Suzuki, H. and Jian, X. and Sarnowski, C. and Evans, T. E. and Bis, J. C. and Eiriksdottir, G. and Sakaue, S. and others}, title = {{Cerebral small vessel disease genomics and its implications across the lifespan}}, journal = {Nature communications}, year = {2020}, doi = {10.1038/s41467-020-19111-2}, pmid = {33293549}, url = {https://doi.org/10.1038/s41467-020-19111-2} } @article{salinas2022-35131906, author = {Salinas, J. and Beiser, A. S. and Samra, J. K. and O'Donnell, A. and DeCarli, C. S. and Gonzales, M. M. and Aparicio, H. J. and Seshadri, S.}, title = {{Association of Loneliness With 10-Year Dementia Risk and Early Markers of Vulnerability for Neurocognitive Decline}}, journal = {Neurology}, year = {2022}, doi = {10.1212/wnl.0000000000200039}, pmid = {35131906}, url = {https://doi.org/10.1212/wnl.0000000000200039} } @article{hwang2022-35511175, author = {Hwang, P. H. and Longstreth, W. T. and Thielke, S. M. and Francis, C. E. and Carone, M. and Kuller, L. H. and Fitzpatrick, A. L.}, title = {{Longitudinal Changes in Hearing and Visual Impairments and Risk of Dementia in Older Adults in the United States}}, journal = {JAMA network open}, year = {2022}, doi = {10.1001/jamanetworkopen.2022.10734}, pmid = {35511175}, url = {https://doi.org/10.1001/jamanetworkopen.2022.10734} } @article{driver2012-22411920, author = {Driver, J. A. and Beiser, A. and Au, R. and Kreger, B. E. and Splansky, G. L. and Kurth, T. and Kiel, D. P. and Lu, K. P. and others}, title = {{Inverse association between cancer and Alzheimer's disease: results from the Framingham Heart Study}}, journal = {BMJ (Clinical research ed.)}, year = {2012}, doi = {10.1136/bmj.e1442}, pmid = {22411920}, url = {https://doi.org/10.1136/bmj.e1442} } @article{peter2025-40513084, author = {Peter, Christopher and Sathe, Aditi and Shashikumar, Niranjana and Pechman, Kimberly R. and Workmeister, Abigail W. and Jackson, Trevor Bryan and Huo, Yuankai and Mukherjee, Shubhabrata and others}, title = {{White Matter Abnormalities and Cognition in Aging and Alzheimer Disease}}, journal = {JAMA Neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.1601}, pmid = {40513084}, url = {https://doi.org/10.1001/jamaneurol.2025.1601} } @article{miyashita2013-23565137, author = {Miyashita, A. and Koike, A. and Jun, G. and Wang, L. S. and Takahashi, S. and Matsubara, E. and Kawarabayashi, T. and Shoji, M. and others}, title = {{SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians}}, journal = {PloS one}, year = {2013}, doi = {10.1371/journal.pone.0058618}, pmid = {23565137}, url = {https://doi.org/10.1371/journal.pone.0058618} } @article{verhaaren2015-25663218, author = {Verhaaren, B. F. and Debette, S. and Bis, J. C. and Smith, J. A. and Ikram, M. K. and Adams, H. H. and Beecham, A. H. and Rajan, K. B. and others}, title = {{Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI}}, journal = {Circulation. Cardiovascular genetics}, year = {2015}, doi = {10.1161/circgenetics.114.000858}, pmid = {25663218}, url = {https://doi.org/10.1161/circgenetics.114.000858} } @article{chauhan2015-25670335, author = {Chauhan, G. and Adams, H. H. H. and Bis, J. C. and Weinstein, G. and Yu, L. and Töglhofer, A. M. and Smith, A. V. and van der Lee, S. J. and others}, title = {{Association of Alzheimer's disease GWAS loci with MRI markers of brain aging}}, journal = {Neurobiology of aging}, year = {2015}, doi = {10.1016/j.neurobiolaging.2014.12.028}, pmid = {25670335}, url = {https://doi.org/10.1016/j.neurobiolaging.2014.12.028} } @article{christensen2018-28726810, author = {Christensen, K. D. and Uhlmann, W. R. and Roberts, J. S. and Linnenbringer, E. and Whitehouse, P. J. and Royal, C. D. M. and Obisesan, T. O. and Cupples, L. A. and others}, title = {{A randomized controlled trial of disclosing genetic risk information for Alzheimer disease via telephone}}, journal = {Genetics in medicine : official journal of the American College of Medical Genetics}, year = {2018}, doi = {10.1038/gim.2017.103}, pmid = {28726810}, url = {https://doi.org/10.1038/gim.2017.103} } @article{satizabal2016-26863354, author = {Satizabal, C. L. and Beiser, A. S. and Chouraki, V. and Chêne, G. and Dufouil, C. and Seshadri, S.}, title = {{Incidence of Dementia over Three Decades in the Framingham Heart Study}}, journal = {The New England journal of medicine}, year = {2016}, doi = {10.1056/nejmoa1504327}, pmid = {26863354}, url = {https://doi.org/10.1056/nejmoa1504327} } @article{seshadri2002-11844848, author = {Seshadri, S. and Beiser, A. and Selhub, J. and Jacques, P. F. and Rosenberg, I. H. and D'Agostino, R. B. and Wilson, P. W. and Wolf, P. A.}, title = {{Plasma homocysteine as a risk factor for dementia and Alzheimer's disease}}, journal = {The New England journal of medicine}, year = {2002}, doi = {10.1056/nejmoa011613}, pmid = {11844848}, url = {https://doi.org/10.1056/nejmoa011613} } @article{sanchez2021-33472953, author = {Sanchez, J. S. and Becker, J. A. and Jacobs, H. I. L. and Hanseeuw, B. J. and Jiang, S. and Schultz, A. P. and Properzi, M. J. and Katz, SR. and others}, title = {{The cortical origin and initial spread of medial temporal tauopathy in Alzheimer's disease assessed with positron emission tomography}}, journal = {Science translational medicine}, year = {2021}, doi = {10.1126/scitranslmed.abc0655}, pmid = {33472953}, url = {https://doi.org/10.1126/scitranslmed.abc0655} } @article{benitez2014-24439484, author = {Benitez, B. A. and Jin, S. C. and Guerreiro, R. and Graham, R. and Lord, J. and Harold, D. and Sims, R. and Lambert, J. C. and others}, title = {{Missense variant in TREML2 protects against Alzheimer's disease}}, journal = {Neurobiology of aging}, year = {2014}, doi = {10.1016/j.neurobiolaging.2013.12.010}, pmid = {24439484}, url = {https://doi.org/10.1016/j.neurobiolaging.2013.12.010} } @article{charidimou2024-39270153, author = {Charidimou, A. and Boulouis, G.}, title = {{Core CSF Biomarker Profile in Cerebral Amyloid Angiopathy: Updated Meta-Analysis}}, journal = {Neurology}, year = {2024}, doi = {10.1212/wnl.0000000000209795}, pmid = {39270153}, url = {https://doi.org/10.1212/wnl.0000000000209795} } @article{ko2022-36399339, author = {Ko, Darae and Lin, Kueiyu Joshua and Bessette, Lily Gui and Lee, Su Been and Walkey, Allan J. and Cheng, Susan C. and Kim, Erin and Glynn, Robert J. and others}, title = {{Trends in Use of Oral Anticoagulants in Older Adults With Newly Diagnosed Atrial Fibrillation, 2010-2020}}, journal = {JAMA Network Open}, year = {2022}, doi = {10.1001/jamanetworkopen.2022.42964}, pmid = {36399339}, url = {https://doi.org/10.1001/jamanetworkopen.2022.42964} } @article{jick2000-11089820, author = {Jick, H. and Zornberg, G. L. and Jick, S. S. and Seshadri, S. and Drachman, D. A.}, title = {{Statins and the risk of dementia}}, journal = {Lancet (London, England)}, year = {2000}, doi = {10.1016/s0140-6736(00)03155-x}, pmid = {11089820}, url = {https://doi.org/10.1016/s0140-6736(00)03155-x} } @article{holstege2022-36411364, author = {Holstege, H. and Hulsman, M. and Charbonnier, C. and Grenier-Boley, B. and Quenez, O. and Grozeva, D. and van Rooij, J. G. J. and Sims, R. and others}, title = {{Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease}}, journal = {Nature genetics}, year = {2022}, doi = {10.1038/s41588-022-01208-7}, pmid = {36411364}, url = {https://doi.org/10.1038/s41588-022-01208-7} } @article{chouraki2015-25217292, author = {Chouraki, V. and Beiser, A. and Younkin, L. and Preis, SR. and Weinstein, G. and Hansson, O. and Skoog, I. and Lambert, J. C. and others}, title = {{Plasma amyloid-β and risk of Alzheimer's disease in the Framingham Heart Study}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2015}, doi = {10.1016/j.jalz.2014.07.001}, pmid = {25217292}, url = {https://doi.org/10.1016/j.jalz.2014.07.001} } @article{kang2024-38959008, author = {Kang, M. and Li, C. and Mahajan, A. and Spat-Lemus, J. and Durape, S. and Chen, J. and Gurnani, A. S. and Devine, S. and others}, title = {{Subjective Cognitive Decline Plus and Longitudinal Assessment and Risk for Cognitive Impairment}}, journal = {JAMA psychiatry}, year = {2024}, doi = {10.1001/jamapsychiatry.2024.1678}, pmid = {38959008}, url = {https://doi.org/10.1001/jamapsychiatry.2024.1678} } @article{himali2023-37902739, author = {Himali, J. J. and Baril, A. A. and Cavuoto, M. G. and Yiallourou, S. and Wiedner, C. D. and Himali, D. and others}, title = {{Association Between Slow-Wave Sleep Loss and Incident Dementia}}, journal = {JAMA Neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.3889}, pmid = {37902739}, url = {https://doi.org/10.1001/jamaneurol.2023.3889} } @article{antolini2021-34531298, author = {Antolini, L. and DiFrancesco, J. C. and Zedde, M. and Basso, G. and Arighi, A. and Shima, A. and Cagnin, A. and Caulo, M. and others}, title = {{Spontaneous ARIA-like Events in Cerebral Amyloid Angiopathy-Related Inflammation: A Multicenter Prospective Longitudinal Cohort Study}}, journal = {Neurology}, year = {2021}, doi = {10.1212/wnl.0000000000012778}, pmid = {34531298}, url = {https://doi.org/10.1212/wnl.0000000000012778} } @article{schilling2017-28350817, author = {Schilling, S. and Tzourio, C. and Soumaré, A. and Kaffashian, S. and Dartigues, J. F. and Ancelin, M. L. and Samieri, C. and Dufouil, C. and others}, title = {{Differential associations of plasma lipids with incident dementia and dementia subtypes in the 3C Study: A longitudinal, population-based prospective cohort study}}, journal = {PLoS medicine}, year = {2017}, doi = {10.1371/journal.pmed.1002265}, pmid = {28350817}, url = {https://doi.org/10.1371/journal.pmed.1002265} } @article{mielke2007-17984453, author = {Mielke, M. M. and Rosenberg, P. B. and Tschanz, J. and Cook, L. and Corcoran, C. and Hayden, K. M. and Norton, M. and Rabins, P. V. and others}, title = {{Vascular factors predict rate of progression in Alzheimer disease}}, journal = {Neurology}, year = {2007}, doi = {10.1212/01.wnl.0000279520.59792.fe}, pmid = {17984453}, url = {https://doi.org/10.1212/01.wnl.0000279520.59792.fe} } @article{rabin2022-35759327, author = {Rabin, J. S. and Nichols, E. and La Joie, R. and Casaletto, K. B. and Palta, P. and Dams-O'Connor, K. and Kumar, R. G. and George, K. M. and others}, title = {{Cerebral amyloid angiopathy interacts with neuritic amyloid plaques to promote tau and cognitive decline}}, journal = {Brain : a journal of neurology}, year = {2022}, doi = {10.1093/brain/awac178}, pmid = {35759327}, url = {https://doi.org/10.1093/brain/awac178} } @article{stokes2020-32852519, author = {Stokes, A. C. and Weiss, J. and Lundberg, D. J. and Xie, W. and Kim, J. K. and Preston, S. H. and Crimmins, E. M.}, title = {{Estimates of the Association of Dementia With US Mortality Levels Using Linked Survey and Mortality Records}}, journal = {JAMA neurology}, year = {2020}, doi = {10.1001/jamaneurol.2020.2831}, pmid = {32852519}, url = {https://doi.org/10.1001/jamaneurol.2020.2831} } @article{mcgrath2017-29117954, author = {McGrath, E. R. and Beiser, A. S. and DeCarli, C. and Plourde, K. L. and Vasan, R. S. and Greenberg, S. M. and Seshadri, S.}, title = {{Blood pressure from mid- to late life and risk of incident dementia}}, journal = {Neurology}, year = {2017}, doi = {10.1212/wnl.0000000000004741}, pmid = {29117954}, url = {https://doi.org/10.1212/wnl.0000000000004741} } @article{spartano2019-31002329, author = {Spartano, N. L. and Davis-Plourde, K. L. and Himali, J. J. and Andersson, C. and Pase, M. P. and Maillard, P. and DeCarli, C. and Murabito, J. M. and others}, title = {{Association of Accelerometer-Measured Light-Intensity Physical Activity With Brain Volume: The Framingham Heart Study}}, journal = {JAMA network open}, year = {2019}, doi = {10.1001/jamanetworkopen.2019.2745}, pmid = {31002329}, url = {https://doi.org/10.1001/jamanetworkopen.2019.2745} } @article{zimmerman2025-40577672, author = {Zimmerman, S. C. and Choi, M. and Jiang, C. and Ferguson, E. L. and Hoffmann, T. J. and Swinnerton, K. and Oni-Orisan, A. and Gilsanz, P. and Meyers, T. J. and Choudhary, V. and others}, title = {{Statin Initiation and Dementia Incidence in a Large Health Care System From 1997 to 2020: A Target Trial Emulation Study}}, journal = {Neurology}, year = {2025}, doi = {10.1212/WNL.0000000000213855}, pmid = {40577672}, url = {https://doi.org/10.1212/WNL.0000000000213855} } @article{rajan2020-32799383, author = {Rajan, K. B. and Aggarwal, N. T. and McAninch, E. A. and Weuve, J. and Barnes, L. L. and Wilson, R. S. and DeCarli, C. and others}, title = {{Remote Blood Biomarkers of Longitudinal Cognitive Outcomes in a Population Study}}, journal = {Annals of neurology}, year = {2020}, doi = {10.1002/ana.25874}, pmid = {32799383}, url = {https://doi.org/10.1002/ana.25874} } @article{rajan2023-36446595, author = {Rajan, K. B. and McAninch, E. A. and Aggarwal, N. T. and Barnes, L. L. and Wilson, R. S. and Weuve, J. and DeCarli, C. S. and Evans, D. A.}, title = {{Longitudinal Changes in Blood Biomarkers of Clinical Alzheimer Disease in a Biracial Population Sample}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000201289}, pmid = {36446595}, url = {https://doi.org/10.1212/wnl.0000000000201289} } @article{linnenbringer2010-20139767, author = {Linnenbringer, E. and Roberts, J. S. and Hiraki, S. and Cupples, L. A. and Green, R. C.}, title = {{"I know what you told me, but this is what I think:" perceived risk of Alzheimer disease among individuals who accurately recall their genetics-based risk estimate}}, journal = {Genetics in medicine : official journal of the American College of Medical Genetics}, year = {2010}, doi = {10.1097/gim.0b013e3181cef9e1}, pmid = {20139767}, url = {https://doi.org/10.1097/gim.0b013e3181cef9e1} } @article{mckee2013-23208308, author = {McKee, A. C. and Stern, R. A. and Nowinski, C. J. and Stein, T. D. and Alvarez, V. E. and Daneshvar, D. H. and Lee, H. S. and Wojtowicz, S. M. and others}, title = {{The spectrum of disease in chronic traumatic encephalopathy}}, journal = {Brain : a journal of neurology}, year = {2013}, doi = {10.1093/brain/aws307}, pmid = {23208308}, url = {https://doi.org/10.1093/brain/aws307} } @article{piccini2012-22235070, author = {Piccini, J. P. and Hammill, B. G. and Sinner, M. F. and Jensen, P. N. and Hernandez, A. F. and Heckbert, SR. and Benjamin, E. J. and Curtis, L. H.}, title = {{Incidence and prevalence of atrial fibrillation and associated mortality among Medicare beneficiaries, 1993-2007}}, journal = {Circulation. Cardiovascular quality and outcomes}, year = {2012}, doi = {10.1161/circoutcomes.111.962688}, pmid = {22235070}, url = {https://doi.org/10.1161/circoutcomes.111.962688} } @article{seshadri1997-9409336, author = {Seshadri, S. and Wolf, P. A. and Beiser, A. and Au, R. and McNulty, K. and White, R. and D'Agostino, R. B.}, title = {{Lifetime risk of dementia and Alzheimer's disease. The impact of mortality on risk estimates in the Framingham Study}}, journal = {Neurology}, year = {1997}, doi = {10.1212/wnl.49.6.1498}, pmid = {9409336}, url = {https://doi.org/10.1212/wnl.49.6.1498} } @article{vandeerlin2010-20154673, author = {Van Deerlin, V. M. and Sleiman, P. M. and Martinez-Lage, M. and Chen-Plotkin, A. and Wang, L. S. and Graff-Radford, N. R. and Dickson, D. W. and Rademakers, R. and others}, title = {{Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions}}, journal = {Nature genetics}, year = {2010}, doi = {10.1038/ng.536}, pmid = {20154673}, url = {https://doi.org/10.1038/ng.536} } @article{rubenstein2024-39312235, author = {Rubenstein, E. and Tewolde, S. and Michals, A. and Weuve, J. and Fortea, J. and Fox, M. P. and Pescador Jimenez, M. and Scott, A. and others}, title = {{Alzheimer Dementia Among Individuals With Down Syndrome}}, journal = {JAMA network open}, year = {2024}, doi = {10.1001/jamanetworkopen.2024.35018}, pmid = {39312235}, url = {https://doi.org/10.1001/jamanetworkopen.2024.35018} } @article{bellenguez2022-35379992, author = {Bellenguez, C. and Küçükali, F. and Jansen, I. E. and Kleineidam, L. and Moreno-Grau, S. and Amin, N. and Naj, A. C. and Campos-Martin, R. and others}, title = {{New insights into the genetic etiology of Alzheimer's disease and related dementias}}, journal = {Nature genetics}, year = {2022}, doi = {10.1038/s41588-022-01024-z}, pmid = {35379992}, url = {https://doi.org/10.1038/s41588-022-01024-z} } @article{stefanidou2020-33097599, author = {Stefanidou, M. and Beiser, A. S. and Himali, J. J. and Peng, T. J. and Devinsky, O. and Seshadri, S. and Friedman, D.}, title = {{Bi-directional association between epilepsy and dementia: The Framingham Heart Study}}, journal = {Neurology}, year = {2020}, doi = {10.1212/wnl.0000000000011077}, pmid = {33097599}, url = {https://doi.org/10.1212/wnl.0000000000011077} } @article{williams2014-24651765, author = {Williams, SR. and Yang, Q. and Chen, F. and Liu, X. and Keene, K. L. and Jacques, P. and Chen, W. M. and Weinstein, G. and others}, title = {{Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke}}, journal = {PLoS genetics}, year = {2014}, doi = {10.1371/journal.pgen.1004214}, pmid = {24651765}, url = {https://doi.org/10.1371/journal.pgen.1004214} } @article{lambert2013-24162737, author = {Lambert, Jean‐Charles and Ibrahim‐Verbaas, Carla A. and Harold, Denise H. and Naj, Adam Christian and Sims, Rebecca and Bellenguez, Céline and others}, title = {{Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease}}, journal = {Nature Genetics}, year = {2013}, doi = {10.1038/ng.2802}, pmid = {24162737}, url = {https://doi.org/10.1038/ng.2802} } @article{zimmerman2023-37878309, author = {Zimmerman, S. C. and Ferguson, E. L. and Choudhary, V. and Ranatunga, D. K. and Oni-Orisan, A. and Hayes-Larson, E. and others}, title = {{Metformin Cessation and Dementia Incidence}}, journal = {JAMA Network Open}, year = {2023}, doi = {10.1001/jamanetworkopen.2023.39723}, pmid = {37878309}, url = {https://doi.org/10.1001/jamanetworkopen.2023.39723} } @article{ferguson2024-39078629, author = {Ferguson, E. L. and Thoma, M. and Buto, P. T. and Wang, J. and Glymour, M. M. and Hoffmann, T. J. and others}, title = {{Visual Impairment, Eye Conditions, and Diagnoses of Neurodegeneration and Dementia}}, journal = {JAMA Network Open}, year = {2024}, doi = {10.1001/jamanetworkopen.2024.24539}, pmid = {39078629}, url = {https://doi.org/10.1001/jamanetworkopen.2024.24539} } @article{giorgio2026-41936382, author = {Giorgio, Katherine and Stephen, John J and Mansolf, Maxwell and Peterson, Elizabeth A and Gross, Alden L and Briceño, Emily M and Levine, Deborah A and Helmer, Catherine and others}, title = {{Risk factors for early-onset and late-onset dementia: a prospective cohort study}}, journal = {The lancet. Healthy longevity}, year = {2026}, doi = {10.1016/j.lanhl.2026.100831}, pmid = {41936382}, url = {https://doi.org/10.1016/j.lanhl.2026.100831} } @article{gogniat2025-40561381, author = {Gogniat, M. A. and Khan, O. A. and Ratangee, B. and Bolton, C. J. and Zhang, P. and Liu, D. and Pechman, K. R. and Yates, A. and others}, title = {{Cross-Sectional and Longitudinal Associations of Neighborhood Disadvantage With Fluid Biomarkers of Neuroinflammation and Neurodegeneration}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000213770}, pmid = {40561381}, url = {https://doi.org/10.1212/wnl.0000000000213770} } @article{christensen2016-26810768, author = {Christensen, K. D. and Roberts, J. S. and Whitehouse, P. J. and Royal, C. D. and Obisesan, T. O. and Cupples, L. A. and Vernarelli, J. A. and Bhatt, D. L. and others}, title = {{Disclosing Pleiotropic Effects During Genetic Risk Assessment for Alzheimer Disease: A Randomized Trial}}, journal = {Annals of internal medicine}, year = {2016}, doi = {10.7326/m15-0187}, pmid = {26810768}, url = {https://doi.org/10.7326/m15-0187} } @article{volandes2011-21254815, author = {Volandes, A. E. and Ferguson, L. A. and Davis, A. D. and Hull, N. C. and Green, M. J. and Chang, Y. and Deep, K. and Paasche-Orlow, M. K.}, title = {{Assessing end-of-life preferences for advanced dementia in rural patients using an educational video: a randomized controlled trial}}, journal = {Journal of palliative medicine}, year = {2011}, doi = {10.1089/jpm.2010.0299}, pmid = {21254815}, url = {https://doi.org/10.1089/jpm.2010.0299} } @article{li2010-20068258, author = {Li, N. C. and Lee, A. and Whitmer, R. A. and Kivipelto, M. and Lawler, E. and Kazis, L. E. and Wolozin, B.}, title = {{Use of angiotensin receptor blockers and risk of dementia in a predominantly male population: prospective cohort analysis}}, journal = {BMJ (Clinical research ed.)}, year = {2010}, doi = {10.1136/bmj.b5465}, pmid = {20068258}, url = {https://doi.org/10.1136/bmj.b5465} } @article{jefferson2015-25700178, author = {Jefferson, A. L. and Beiser, A. S. and Himali, J. J. and Seshadri, S. and O'Donnell, C. J. and Manning, W. J. and Wolf, P. A. and Au, R. and others}, title = {{Low cardiac index is associated with incident dementia and Alzheimer disease: the Framingham Heart Study}}, journal = {Circulation}, year = {2015}, doi = {10.1161/circulationaha.114.012438}, pmid = {25700178}, url = {https://doi.org/10.1161/circulationaha.114.012438} } @article{kolo2025-41191359, author = {Kolo, Francis Babaman and Lu, Sophia Francesca DP and Beiser, Alexa S. and Francis, Lily and van Lent, Debora Melo and Gireud, Monica and Himali, Jayandra Jung and Ghosh, Saptaparni and others}, title = {{Hearing Loss, Brain Structure, Cognition, and Dementia Risk in the Framingham Heart Study}}, journal = {JAMA Network Open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.39209}, pmid = {41191359}, url = {https://doi.org/10.1001/jamanetworkopen.2025.39209} } @article{weuve2018-28863046, author = {Weuve, J. and Barnes, L. L. and Mendes de Leon, C. F. and Rajan, K. B. and Beck, T. and Aggarwal, N. T. and Hebert, L. E. and Bennett, D. A. and others}, title = {{Cognitive Aging in Black and White Americans: Cognition, Cognitive Decline, and Incidence of Alzheimer Disease Dementia}}, journal = {Epidemiology (Cambridge, Mass.)}, year = {2018}, doi = {10.1097/ede.0000000000000747}, pmid = {28863046}, url = {https://doi.org/10.1097/ede.0000000000000747} } @article{dickerson2011-21490323, author = {Dickerson, B. C. and Stoub, T. R. and Shah, R. C. and Sperling, R. A. and Killiany, R. J. and Albert, M. S. and Hyman, B. T. and Blacker, D. and others}, title = {{Alzheimer-signature MRI biomarker predicts AD dementia in cognitively normal adults}}, journal = {Neurology}, year = {2011}, doi = {10.1212/wnl.0b013e3182166e96}, pmid = {21490323}, url = {https://doi.org/10.1212/wnl.0b013e3182166e96} } @article{cote2020-33505979, author = {Cote, A. C. and Phelps, R. J. and Kabiri, N. S. and Bhangu, J. S. and Thomas, K. K.}, title = {{Evaluation of Wearable Technology in Dementia: A Systematic Review and Meta-Analysis}}, journal = {Frontiers in medicine}, year = {2020}, doi = {10.3389/fmed.2020.501104}, pmid = {33505979}, url = {https://doi.org/10.3389/fmed.2020.501104} } @article{pludowski2013-23542507, author = {Pludowski, P. and Holick, M. F. and Pilz, S. and Wagner, C. L. and Hollis, B. W. and Grant, W. B. and Shoenfeld, Y. and Lerchbaum, E. and others}, title = {{Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality-a review of recent evidence}}, journal = {Autoimmunity reviews}, year = {2013}, doi = {10.1016/j.autrev.2013.02.004}, pmid = {23542507}, url = {https://doi.org/10.1016/j.autrev.2013.02.004} } @article{beecham2014-25188341, author = {Beecham, G. W. and Hamilton, K. and Naj, A. C. and Martin, E. R. and Huentelman, M. and Myers, A. J. and Corneveaux, J. J. and Hardy, J. and others}, title = {{Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias}}, journal = {PLoS genetics}, year = {2014}, doi = {10.1371/journal.pgen.1004606}, pmid = {25188341}, url = {https://doi.org/10.1371/journal.pgen.1004606} } @article{pederson2026-41849727, author = {Pederson, Anna M. and Buto, Peter T. and Zimmerman, Scott C. and Velez, Mabeline and Sims, Kendra D. and Murchland, Audrey R. and Wang, Jingxuan and Brennan, Alana T. and others}, title = {{Type 1 Diabetes and Incident Dementia}}, journal = {Neurology}, year = {2026}, doi = {10.1212/wnl.0000000000214805}, pmid = {41849727}, url = {https://doi.org/10.1212/wnl.0000000000214805} } @article{yiallourou2025-40377976, author = {Yiallourou, Stephanie R and Baril, Andrée‐Ann and Wiedner, Crystal and Misialek, Jeffrey R. and Kline, Christopher E. and Harrison, Stephanie Litwack and Cannon, Ethan J. and Yang, Qiong and others}, title = {{Sleep architecture and dementia risk in adults: an analysis of 5 cohorts from the Sleep and Dementia Consortium}}, journal = {SLEEP}, year = {2025}, doi = {10.1093/sleep/zsaf129}, pmid = {40377976}, url = {https://doi.org/10.1093/sleep/zsaf129} } @article{wang2025-40266617, author = {Wang, Jingxuan and Choi, Minhyuk and Buto, Peter T. and Kelly, John Daniel and La Joie, Renaud and Kornak, John and Zimmerman, Scott C. and Chen, Ruijia and others}, title = {{Detection Bias in EHR-Based Research on Clinical Exposures and Dementia}}, journal = {JAMA Network Open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.6637}, pmid = {40266617}, url = {https://doi.org/10.1001/jamanetworkopen.2025.6637} } @article{duering2023-37236211, author = {Duering, Marco and Biessels, Geert Jan and Brodtmann, Amy G. and Chen, Christopher and Cordonnier, Charlotte and de Leeuw, Frank‐Erik and Debette, Stéphanie and Frayne, Richard and Jouvent, Éric and Rost, Natalia S. and ter Telgte, Annemieke and Salman, Rustam Al‐Shahi and Backes, Walter H. and Bae, Hee‐Joon and Brown, Rosalind and Chabriat, Hugues and De Luca, Alberto and DeCarli, Charles S and Dewenter, Anna and Doubal, Fergus and Ewers, Michael and Field, Thalia Shoshana and Ganesh, Aravind and Greenberg, Steven Mark and Helmer, Karl G. and Hilal, Saima and Jochems, Angela C.C. and Jokinen, Hanna and Kuijf, Hugo J. and Lam, Bonnie Y. K. and Lebenberg, Jessica and MacIntosh, Bradley John and Maillard, Pauline and Mok, Vincent and Pantoni, Leonardo and Rudilosso, Salvatore and Satizábal, Claudia Liliana and Schirmer, Markus D. and Schmidt, Reinhold and Smith, Colin and Staals, Julie and Thrippleton, Michael J. and van Veluw, Susanne J. and Vemuri, Prashanthi and Wang, Yilong and Werring, David John and Zedde, Marialuisa and Akinyemi, Rufus and Del Brutto, Óscar H. and Markus, Hugh Stephen and Zhu, Yi‐Cheng and Smith, Eric Edward and Dichgans, Martin and Wardlaw, Joanna Marguerite}, title = {{Neuroimaging standards for research into small vessel disease—advances since 2013}}, journal = {The Lancet Neurology}, year = {2023}, doi = {10.1016/s1474-4422(23)00131-x}, pmid = {37236211}, url = {https://doi.org/10.1016/s1474-4422(23)00131-x} } @article{quiroz2020-32470423, author = {Quiroz, Y. T. and Zetterberg, H. and Reiman, E. M. and Chen, Y. and Su, Y. and Fox-Fuller, J. T. and Garcia, G. and Villegas, A. and others}, title = {{Plasma neurofilament light chain in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional and longitudinal cohort study}}, journal = {The Lancet. Neurology}, year = {2020}, doi = {10.1016/s1474-4422(20)30137-x}, pmid = {32470423}, url = {https://doi.org/10.1016/s1474-4422(20)30137-x} } @article{tao2018-30646251, author = {Tao, Q. and Ang, T. F. A. and DeCarli, C. and Auerbach, S. H. and Devine, S. and Stein, T. D. and Zhang, X. and Massaro, J. and others}, title = {{Association of Chronic Low-grade Inflammation With Risk of Alzheimer Disease in ApoE4 Carriers}}, journal = {JAMA network open}, year = {2018}, doi = {10.1001/jamanetworkopen.2018.3597}, pmid = {30646251}, url = {https://doi.org/10.1001/jamanetworkopen.2018.3597} } @article{chao2008-18317253, author = {Chao, S. and Roberts, J. S. and Marteau, T. M. and Silliman, R. and Cupples, L. A. and Green, R. C.}, title = {{Health behavior changes after genetic risk assessment for Alzheimer disease: The REVEAL Study}}, journal = {Alzheimer disease and associated disorders}, year = {2008}, doi = {10.1097/wad.0b013e31815a9dcc}, pmid = {18317253}, url = {https://doi.org/10.1097/wad.0b013e31815a9dcc} } @article{rajabli2018-30517106, author = {Rajabli, F. and Feliciano, B. E. and Celis, K. and Hamilton-Nelson, K. L. and Whitehead, P. L. and Adams, L. D. and Bussies, P. L. and Manrique, C. P. and others}, title = {{Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations}}, journal = {PLoS genetics}, year = {2018}, doi = {10.1371/journal.pgen.1007791}, pmid = {30517106}, url = {https://doi.org/10.1371/journal.pgen.1007791} } @article{qian2017-28323826, author = {Qian, J. and Wolters, F. J. and Beiser, A. and Haan, M. and Ikram, M. A. and Karlawish, J. and Langbaum, J. B. and Neuhaus, J. M. and others}, title = {{APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts}}, journal = {PLoS medicine}, year = {2017}, doi = {10.1371/journal.pmed.1002254}, pmid = {28323826}, url = {https://doi.org/10.1371/journal.pmed.1002254} } @article{roberts2003-12794385, author = {Roberts, J. S. and LaRusse, S. A. and Katzen, H. and Whitehouse, P. J. and Barber, M. and Post, S. G. and Relkin, N. and Quaid, K. and others}, title = {{Reasons for seeking genetic susceptibility testing among first-degree relatives of people with Alzheimer disease}}, journal = {Alzheimer disease and associated disorders}, year = {2003}, doi = {10.1097/00002093-200304000-00006}, pmid = {12794385}, url = {https://doi.org/10.1097/00002093-200304000-00006} } @article{reiman2012-23137948, author = {Reiman, E. M. and Quiroz, Y. T. and Fleisher, A. S. and Chen, K. and Velez-Pardo, C. and Jimenez-Del-Rio, M. and Fagan, A. M. and Shah, A. R. and others}, title = {{Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study}}, journal = {The Lancet. Neurology}, year = {2012}, doi = {10.1016/s1474-4422(12)70228-4}, pmid = {23137948}, url = {https://doi.org/10.1016/s1474-4422(12)70228-4} } @article{qiu2020-32357201, author = {Qiu, S. and Joshi, P. S. and Miller, M. I. and Xue, C. and Zhou, X. and Karjadi, C. and Chang, G. H. and Joshi, A. S. and others}, title = {{Development and validation of an interpretable deep learning framework for Alzheimer's disease classification}}, journal = {Brain : a journal of neurology}, year = {2020}, doi = {10.1093/brain/awaa137}, pmid = {32357201}, url = {https://doi.org/10.1093/brain/awaa137} } @article{ivan2004-15118167, author = {Ivan, C. S. and Seshadri, S. and Beiser, A. and Au, R. and Kase, C. S. and Kelly-Hayes, M. and Wolf, P. A.}, title = {{Dementia after stroke: the Framingham Study}}, journal = {Stroke}, year = {2004}, doi = {10.1161/01.str.0000127810.92616.78}, pmid = {15118167}, url = {https://doi.org/10.1161/01.str.0000127810.92616.78} } @article{weinstein2014-24276217, author = {Weinstein, G. and Beiser, A. S. and Choi, S. H. and Preis, SR. and Chen, T. C. and Vorgas, D. and Au, R. and Pikula, A. and others}, title = {{Serum brain-derived neurotrophic factor and the risk for dementia: the Framingham Heart Study}}, journal = {JAMA neurology}, year = {2014}, doi = {10.1001/jamaneurol.2013.4781}, pmid = {24276217}, url = {https://doi.org/10.1001/jamaneurol.2013.4781} } @article{atherton2022-35759276, author = {Atherton, K. and Han, X. and Chung, J. and Cherry, J. D. and Baucom, Z. and Saltiel, N. and Nair, E. and Abdolmohammadi, B. and others}, title = {{Association of APOE Genotypes and Chronic Traumatic Encephalopathy}}, journal = {JAMA neurology}, year = {2022}, doi = {10.1001/jamaneurol.2022.1634}, pmid = {35759276}, url = {https://doi.org/10.1001/jamaneurol.2022.1634} } @article{krasemann2017-28930663, author = {Krasemann, S. and Madore, C. and Cialic, R. and Baufeld, C. and Calcagno, N. and El Fatimy, R. and Beckers, L. and O'Loughlin, E. and others}, title = {{The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases}}, journal = {Immunity}, year = {2017}, doi = {10.1016/j.immuni.2017.08.008}, pmid = {28930663}, url = {https://doi.org/10.1016/j.immuni.2017.08.008} } @article{mcgrath2022-35584926, author = {McGrath, E. R. and Beiser, A. S. and O'Donnell, A. and Himali, J. J. and Pase, M. P. and Satizabal, C. L. and Seshadri, S.}, title = {{Determining Vascular Risk Factors for Dementia and Dementia Risk Prediction Across Mid- to Later Life: The Framingham Heart Study}}, journal = {Neurology}, year = {2022}, doi = {10.1212/wnl.0000000000200521}, pmid = {35584926}, url = {https://doi.org/10.1212/wnl.0000000000200521} } @article{grill2026-41910973, author = {Grill, Joshua D. and RAMAN, REMA and Wang, Shunran and Ernstrom, Karin B. and Andrews, Patricia and Appleby, Brian Stephen and Bhangu, Jaspreet S. and Dhadda, Shobha and others}, title = {{Amyloid Imaging and APOE Genotype Disclosure and Short-Term Psychological Distress}}, journal = {JAMA Network Open}, year = {2026}, doi = {10.1001/jamanetworkopen.2026.3845}, pmid = {41910973}, url = {https://doi.org/10.1001/jamanetworkopen.2026.3845} } @article{weinstein2025-39863327, author = {Weinstein, Galit and Kojis, Daniel J. and Banerjee, Ayantika and Seshadri, Sudha S. and Walker, Maura E. and Beiser, Alexa S.}, title = {{Ultra-processed food consumption and risk of dementia and Alzheimer's disease: The Framingham Heart Study}}, journal = {The Journal of Prevention of Alzheimer s Disease}, year = {2025}, doi = {10.1016/j.tjpad.2024.100042}, pmid = {39863327}, url = {https://doi.org/10.1016/j.tjpad.2024.100042} } @article{saczynski2010-20603483, author = {Saczynski, J. S. and Beiser, A. and Seshadri, S. and Auerbach, S. and Wolf, P. A. and Au, R.}, title = {{Depressive symptoms and risk of dementia: the Framingham Heart Study}}, journal = {Neurology}, year = {2010}, doi = {10.1212/wnl.0b013e3181e62138}, pmid = {20603483}, url = {https://doi.org/10.1212/wnl.0b013e3181e62138} } @article{allen2012-22722634, author = {Allen, M. and Zou, F. and Chai, H. S. and Younkin, C. S. and Crook, J. and Pankratz, V. S. and Carrasquillo, M. M. and Rowley, C. N. and others}, title = {{Novel late-onset Alzheimer disease loci variants associate with brain gene expression}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e3182605801}, pmid = {22722634}, url = {https://doi.org/10.1212/wnl.0b013e3182605801} } @article{dumitriu2012-22761592, author = {Dumitriu, A. and Latourelle, J. C. and Hadzi, T. C. and Pankratz, N. and Garza, D. and Miller, J. P. and Vance, J. M. and Foroud, T. and others}, title = {{Gene expression profiles in Parkinson disease prefrontal cortex implicate FOXO1 and genes under its transcriptional regulation}}, journal = {PLoS genetics}, year = {2012}, doi = {10.1371/journal.pgen.1002794}, pmid = {22761592}, url = {https://doi.org/10.1371/journal.pgen.1002794} } @article{roberts2012-22498844, author = {Roberts, J. S. and Chen, C. A. and Uhlmann, W. R. and Green, R. C.}, title = {{Effectiveness of a condensed protocol for disclosing APOE genotype and providing risk education for Alzheimer disease}}, journal = {Genetics in medicine : official journal of the American College of Medical Genetics}, year = {2012}, doi = {10.1038/gim.2012.37}, pmid = {22498844}, url = {https://doi.org/10.1038/gim.2012.37} } @article{crary2014-25348064, author = {Crary, J. F. and Trojanowski, J. Q. and Schneider, J. A. and Abisambra, J. F. and Abner, E. L. and Alafuzoff, I. and Arnold, S. E. and Attems, J. and others}, title = {{Primary age-related tauopathy (PART): a common pathology associated with human aging}}, journal = {Acta neuropathologica}, year = {2014}, doi = {10.1007/s00401-014-1349-0}, pmid = {25348064}, url = {https://doi.org/10.1007/s00401-014-1349-0} } @article{katz2021-33722990, author = {Katz, D. I. and Bernick, C. and Dodick, D. W. and Mez, J. and Mariani, M. L. and Adler, C. H. and Alosco, M. L. and Balcer, L. J. and others}, title = {{National Institute of Neurological Disorders and Stroke Consensus Diagnostic Criteria for Traumatic Encephalopathy Syndrome}}, journal = {Neurology}, year = {2021}, doi = {10.1212/wnl.0000000000011850}, pmid = {33722990}, url = {https://doi.org/10.1212/wnl.0000000000011850} } @article{eyler2019-31177210, author = {Eyler, L. T. and Elman, J. A. and Hatton, S. N. and Gough, S. and Mischel, A. K. and Hagler, D. J. and Franz, C. E. and Docherty, A. and others}, title = {{Resting State Abnormalities of the Default Mode Network in Mild Cognitive Impairment: A Systematic Review and Meta-Analysis}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2019}, doi = {10.3233/jad-180847}, pmid = {31177210}, url = {https://doi.org/10.3233/jad-180847} } @article{westwood2017-28228567, author = {Westwood, A. J. and Beiser, A. and Jain, N. and Himali, J. J. and DeCarli, C. and Auerbach, S. H. and Pase, M. P. and Seshadri, S.}, title = {{Prolonged sleep duration as a marker of early neurodegeneration predicting incident dementia}}, journal = {Neurology}, year = {2017}, doi = {10.1212/wnl.0000000000003732}, pmid = {28228567}, url = {https://doi.org/10.1212/wnl.0000000000003732} } @article{weinstein2019-30768625, author = {Weinstein, G. and Davis-Plourde, K. L. and Conner, S. and Himali, J. J. and Beiser, A. S. and Lee, A. and Rawlings, A. M. and Sedaghat, S. and others}, title = {{Association of metformin, sulfonylurea and insulin use with brain structure and function and risk of dementia and Alzheimer's disease: Pooled analysis from 5 cohorts}}, journal = {PloS one}, year = {2019}, doi = {10.1371/journal.pone.0212293}, pmid = {30768625}, url = {https://doi.org/10.1371/journal.pone.0212293} } @article{jun2014-25043464, author = {Jun, G. and Asai, H. and Zeldich, E. and Drapeau, E. and Chen, C. and Chung, J. and Park, J. H. and Kim, S. and others}, title = {{PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation}}, journal = {Annals of neurology}, year = {2014}, doi = {10.1002/ana.24219}, pmid = {25043464}, url = {https://doi.org/10.1002/ana.24219} } @article{chen2023-37584418, author = {Chen, J. and Doyle, M. F. and Fang, Y. and Mez, J. and Crane, P. K. and Scollard, P. and {ADSP Data Harmonization Consortium Cognitive Harmonization Core} and Satizabal, C. L. and others}, title = {{Peripheral inflammatory biomarkers are associated with cognitive function and dementia: Framingham Heart Study Offspring cohort}}, journal = {Aging cell}, year = {2023}, doi = {10.1111/acel.13955}, pmid = {37584418}, url = {https://doi.org/10.1111/acel.13955} } @article{ramoscejudo2021-34916927, author = {Ramos-Cejudo, J. and Johnson, A. D. and Beiser, A. and Seshadri, S. and Salinas, J. and Berger, J. S. and Fillmore, N. R. and Do, N. and others}, title = {{The Neutrophil to Lymphocyte Ratio Is Associated With the Risk of Subsequent Dementia in the Framingham Heart Study}}, journal = {Frontiers in aging neuroscience}, year = {2021}, doi = {10.3389/fnagi.2021.773984}, pmid = {34916927}, url = {https://doi.org/10.3389/fnagi.2021.773984} } @article{marino2025-41259024, author = {Marino, Francesca and Lyu, Chenglin and Li, Yuqing and Liu, Tianyu and Au, Rhoda and Hwang, Phillip H}, title = {{Physical Activity Over the Adult Life Course and Risk of Dementia in the Framingham Heart Study}}, journal = {JAMA Network Open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.44439}, pmid = {41259024}, url = {https://doi.org/10.1001/jamanetworkopen.2025.44439} } @article{wang2025-40938598, author = {Wang, Jinqi and Jiao, Danyang and Zhao, Xiaoyu and Tian, Yixing and Li, Haibin and Li, Xia and Sheng, Chen and Tao, Lixin and others}, title = {{Childhood Loneliness and Cognitive Decline and Dementia Risk in Middle-Aged and Older Adults}}, journal = {JAMA Network Open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.31493}, pmid = {40938598}, url = {https://doi.org/10.1001/jamanetworkopen.2025.31493} } @article{nelson2012-22487856, author = {Nelson, Peter T. and Alafuzoff, Irina I. and Bigio, Eileen H. and Bouras, Constantin and Braak, Heiko and Cairns, Nigel J. and Castellani, Rudolph J. and Crain, Barbara J. and others}, title = {{Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature}}, journal = {Journal of Neuropathology \& Experimental Neurology}, year = {2012}, doi = {10.1097/nen.0b013e31825018f7}, pmid = {22487856}, url = {https://doi.org/10.1097/nen.0b013e31825018f7} } @article{fischl2002-11832223, author = {Fischl, Bruce R. and Salat, David H. and Busa, Evelina and Albert, Marilyn and Dieterich, Megan and Haselgrove, Christian and van der Kouwe, Andre J. W. and Killiany, Ronald and others}, title = {{Whole Brain Segmentation}}, journal = {Neuron}, year = {2002}, doi = {10.1016/s0896-6273(02)00569-x}, pmid = {11832223}, url = {https://doi.org/10.1016/s0896-6273(02)00569-x} } @article{nicolas2025-40533518, author = {Nicolas, A. and Sherva, R. and Grenier-Boley, B. and Kim, Y. and Kikuchi, M. and Timsina, J. and de Rojas, I. and Dalmasso, M. C. and Zhou, X. and Le Guen, Y. and Arboleda-Bustos, C. E. and Camargos Bicalho, M. A. and others}, title = {{Transferability of European-derived Alzheimer's disease polygenic risk scores across multiancestry populations}}, journal = {Nature genetics}, year = {2025}, doi = {10.1038/s41588-025-02227-w}, pmid = {40533518}, url = {https://doi.org/10.1038/s41588-025-02227-w} } @article{guo2000-10746604, author = {Guo, Z. and Cupples, L. A. and Kurz, A. and Auerbach, S. H. and Volicer, L. and Chui, H. and Green, R. C. and Sadovnick, A. D. and others}, title = {{Head injury and the risk of AD in the MIRAGE study}}, journal = {Neurology}, year = {2000}, doi = {10.1212/wnl.54.6.1316}, pmid = {10746604}, url = {https://doi.org/10.1212/wnl.54.6.1316} } @article{reiman2020-32015339, author = {Reiman, E. M. and Arboleda-Velasquez, J. F. and Quiroz, Y. T. and Huentelman, M. J. and Beach, T. G. and Caselli, R. J. and Chen, Y. and Su, Y. and others}, title = {{Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study}}, journal = {Nature communications}, year = {2020}, doi = {10.1038/s41467-019-14279-8}, pmid = {32015339}, url = {https://doi.org/10.1038/s41467-019-14279-8} } @article{orkaby2017-28954880, author = {Orkaby, A. R. and Cho, K. and Cormack, J. and Gagnon, D. R. and Driver, J. A.}, title = {{Metformin vs sulfonylurea use and risk of dementia in US veterans aged ≥65 years with diabetes}}, journal = {Neurology}, year = {2017}, doi = {10.1212/wnl.0000000000004586}, pmid = {28954880}, url = {https://doi.org/10.1212/wnl.0000000000004586} } @article{mckee2016-26667418, author = {McKee, A. C. and Cairns, N. J. and Dickson, D. W. and Folkerth, R. D. and Keene, C. D. and Litvan, I. and Perl, D. P. and Stein, T. D. and others}, title = {{The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy}}, journal = {Acta neuropathologica}, year = {2016}, doi = {10.1007/s00401-015-1515-z}, pmid = {26667418}, url = {https://doi.org/10.1007/s00401-015-1515-z} } @article{smith2008-18195145, author = {Smith, E. E. and Egorova, S. and Blacker, D. and Killiany, R. J. and Muzikansky, A. and Dickerson, B. C. and Tanzi, R. E. and Albert, M. S. and others}, title = {{Magnetic resonance imaging white matter hyperintensities and brain volume in the prediction of mild cognitive impairment and dementia}}, journal = {Archives of neurology}, year = {2008}, doi = {10.1001/archneurol.2007.23}, pmid = {18195145}, url = {https://doi.org/10.1001/archneurol.2007.23} } @article{mcbain2019-31485970, author = {McBain, R. K. and Sousa, J. L. and Rose, A. J. and Baxi, S. M. and Faherty, L. J. and Taplin, C. and Chappel, A. and Fischer, S. H.}, title = {{Impact of Project ECHO Models of Medical Tele-Education: a Systematic Review}}, journal = {Journal of general internal medicine}, year = {2019}, doi = {10.1007/s11606-019-05291-1}, pmid = {31485970}, url = {https://doi.org/10.1007/s11606-019-05291-1} } @article{debette2010-20167919, author = {Debette, S. and Beiser, A. and DeCarli, C. and Au, R. and Himali, J. J. and Kelly-Hayes, M. and Romero, JR. and Kase, C. S. and others}, title = {{Association of MRI markers of vascular brain injury with incident stroke, mild cognitive impairment, dementia, and mortality: the Framingham Offspring Study}}, journal = {Stroke}, year = {2010}, doi = {10.1161/strokeaha.109.570044}, pmid = {20167919}, url = {https://doi.org/10.1161/strokeaha.109.570044} } @article{rogaeva2007-17220890, author = {Rogaeva, E. and Meng, Y. and Lee, J. H. and Gu, Y. and Kawarai, T. and Zou, F. and Katayama, T. and Baldwin, C. T. and others}, title = {{The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease}}, journal = {Nature genetics}, year = {2007}, doi = {10.1038/ng1943}, pmid = {17220890}, url = {https://doi.org/10.1038/ng1943} } @article{coogan2025-40189829, author = {Coogan, Patricia F. and Delp, Lauren and Hicks, Jacqueline Milton and Hill‐Jarrett, Tanisha G. and Ortiz, Kasim S. and James, Bryan D. and Bailey, Zinzi and Barnes, Lisa Laverne and others}, title = {{Neighborhood disadvantage and the incidence of dementia in US Black women}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70125}, pmid = {40189829}, url = {https://doi.org/10.1002/alz.70125} } @article{pinheiro2025-40953349, author = {Pinheiro, Adlin and Ekenze, Oluchi Stella and Aparicio, Hugo Javier and Beiser, Alexa S. and DeCarli, Charles S and Demissie, Serkalem and Seshadri, Sudha S. and Romero, Jose Rafael}, title = {{Multimarker Cerebral Small Vessel Disease Score and Risk of Incident Dementia in the Framingham Heart Study}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000214113}, pmid = {40953349}, url = {https://doi.org/10.1212/wnl.0000000000214113} } @article{desikan2006-16530430, author = {Desikan, Rahul S. and Ségonne, Florent and Fischl, Bruce R. and Quinn, Brian T. and Dickerson, Bradford Clark and Blacker, Deborah and Buckner, Randy Lee and Dale, Anders Martin and others}, title = {{An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest}}, journal = {NeuroImage}, year = {2006}, doi = {10.1016/j.neuroimage.2006.01.021}, pmid = {16530430}, url = {https://doi.org/10.1016/j.neuroimage.2006.01.021} } @article{asai2015-26436904, author = {Asai, Hirohide and Ikezu, Seiko and Tsunoda, Satoshi and Medalla, Maria and Luebke, Jennifer Irene and Haydar, Tarik F. and Wolozin, Benjamin L. and Butovsky, Oleg and Kügler, Sebastian and Ikezu, Tsuneya}, title = {{Depletion of microglia and inhibition of exosome synthesis halt tau propagation}}, journal = {Nature Neuroscience}, year = {2015}, doi = {10.1038/nn.4132}, pmid = {26436904}, url = {https://doi.org/10.1038/nn.4132} } @article{vanderlee2018-29316447, author = {van der Lee, S. J. and Teunissen, C. E. and Pool, R. and Shipley, M. J. and Teumer, A. and Chouraki, V. and Melo van Lent, D. and Tynkkynen, J. and others}, title = {{Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2018}, doi = {10.1016/j.jalz.2017.11.012}, pmid = {29316447}, url = {https://doi.org/10.1016/j.jalz.2017.11.012} } @article{imfeld2012-22458300, author = {Imfeld, P. and Bodmer, M. and Jick, S. S. and Meier, C. R.}, title = {{Metformin, other antidiabetic drugs, and risk of Alzheimer's disease: a population-based case-control study}}, journal = {Journal of the American Geriatrics Society}, year = {2012}, doi = {10.1111/j.1532-5415.2012.03916.x}, pmid = {22458300}, url = {https://doi.org/10.1111/j.1532-5415.2012.03916.x} } @article{chene2015-24418058, author = {Chêne, G. and Beiser, A. and Au, R. and Preis, SR. and Wolf, P. A. and Dufouil, C. and Seshadri, S.}, title = {{Gender and incidence of dementia in the Framingham Heart Study from mid-adult life}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2015}, doi = {10.1016/j.jalz.2013.10.005}, pmid = {24418058}, url = {https://doi.org/10.1016/j.jalz.2013.10.005} } @article{echouffotcheugui2018-30355700, author = {Echouffo-Tcheugui, J. B. and Conner, S. C. and Himali, J. J. and Maillard, P. and DeCarli, C. S. and Beiser, A. S. and Vasan, R. S. and Seshadri, S.}, title = {{Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000006549}, pmid = {30355700}, url = {https://doi.org/10.1212/wnl.0000000000006549} } @article{pase2018-30232248, author = {Pase, M. P. and Davis-Plourde, K. and Himali, J. J. and Satizabal, C. L. and Aparicio, H. and Seshadri, S. and Beiser, A. S. and DeCarli, C.}, title = {{Vascular risk at younger ages most strongly associates with current and future brain volume}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000006360}, pmid = {30232248}, url = {https://doi.org/10.1212/wnl.0000000000006360} } @article{wang2025-41461059, author = {Wang, Wendy and Wanigatunga, Amal Asiri and Etzkorn, Lacey and Rabinowitz, Jill A. and Palta, Priya and Pike, James Russell and Dougherty, Ryan James and Zipunnikov, Vadim and others}, title = {{Association Between Circadian Rest-Activity Rhythms and Incident Dementia in Older Adults}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000214513}, pmid = {41461059}, url = {https://doi.org/10.1212/wnl.0000000000214513} } @article{burton2026-41615690, author = {Burton, Rebecca and Durape, Shruti and Price, Eden and Chien‐Young, Kurtis and Joshi, Prajakta S. and Yhang, Eukyung and Liu, Yulin and Devine, Sherral and others}, title = {{Traumatic Brain Injury and All-Cause and Dementia-Related Mortality in the Framingham Heart Study}}, journal = {JAMA Network Open}, year = {2026}, doi = {10.1001/jamanetworkopen.2025.55138}, pmid = {41615690}, url = {https://doi.org/10.1001/jamanetworkopen.2025.55138} } @article{koton2026-41989779, author = {Koton, Silvia and Gross, Alden L. and Aparicio, Hugo Javier and Beiser, Alexa S. and Briceño, Emily M. and Coresh, Josef and Elkind, Mitchell S.V. and Giordani, Bruno and others}, title = {{Ischemic Stroke Incidence and Severity and Poststroke Cognitive Decline and Incident Dementia}}, journal = {JAMA Network Open}, year = {2026}, doi = {10.1001/jamanetworkopen.2026.8900}, pmid = {41989779}, url = {https://doi.org/10.1001/jamanetworkopen.2026.8900} } @article{decalignon2012-22365544, author = {de Calignon, Alix and Polydoro, Manuela and Suárez‐Calvet, Marc and William, Christopher M. and Adamowicz, David H. and Kopeikina, Kathy J. and Pitstick, Rose and Sahara, Naruhiko and Ashe, Karen H. and Carlson, George A. and Spires‐Jones, Tara L. and Hyman, Bradley T.}, title = {{Propagation of Tau Pathology in a Model of Early Alzheimer's Disease}}, journal = {Neuron}, year = {2012}, doi = {10.1016/j.neuron.2011.11.033}, pmid = {22365544}, url = {https://doi.org/10.1016/j.neuron.2011.11.033} } @article{rajabli2023-36539198, author = {Rajabli, F. and Tosto, G. and Hamilton-Nelson, K. L. and Kunkle, B. W. and Vardarajan, B. N. and Naj, A. and Whitehead, P. G. and Gardner, O. K. and Bush, W. S. and Sariya, S. and Mayeux, R. P. and Farrer, L. A. and others}, title = {{Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans}}, journal = {Alzheimer's \& Dementia}, year = {2023}, doi = {10.1002/alz.12865}, pmid = {36539198}, url = {https://doi.org/10.1002/alz.12865} } @article{killiany2000-10762153, author = {Killiany, R. J. and Gomez-Isla, T. and Moss, M. and Kikinis, R. and Sandor, T. and Jolesz, F. and Tanzi, R. and Jones, K. and others}, title = {{Use of structural magnetic resonance imaging to predict who will get Alzheimer's disease}}, journal = {Annals of neurology}, year = {2000}, doi = {10.1002/1531-8249(200004)47:4<430::aid-ana5>3.0.co;2-i}, pmid = {10762153}, url = {https://doi.org/10.1002/1531-8249(200004)47:4<430::aid-ana5>3.0.co;2-i} } @article{seshadri2006-16397184, author = {Seshadri, S. and Beiser, A. and Kelly-Hayes, M. and Kase, C. S. and Au, R. and Kannel, W. B. and Wolf, P. A.}, title = {{The lifetime risk of stroke: estimates from the Framingham Study}}, journal = {Stroke}, year = {2006}, doi = {10.1161/01.str.0000199613.38911.b2}, pmid = {16397184}, url = {https://doi.org/10.1161/01.str.0000199613.38911.b2} } @article{qamar2018-29677515, author = {Qamar, S. and Wang, G. and Randle, S. J. and Ruggeri, F. S. and Varela, J. A. and Lin, J. Q. and Phillips, E. C. and Miyashita, A. and others}, title = {{FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions}}, journal = {Cell}, year = {2018}, doi = {10.1016/j.cell.2018.03.056}, pmid = {29677515}, url = {https://doi.org/10.1016/j.cell.2018.03.056} } @article{yuan2022-37208066, author = {Yuan, J. and Liu, X. and Liu, C. and Ang, A. F. and Massaro, J. and Devine, S. A. and Auerbach, S. H. and Blusztajn, J. K. and others}, title = {{Is dietary choline intake related to dementia and Alzheimer's disease risks? Results from the Framingham Heart Study}}, journal = {The American journal of clinical nutrition}, year = {2022}, doi = {10.1093/ajcn/nqac193}, pmid = {37208066}, url = {https://doi.org/10.1093/ajcn/nqac193} } @article{heneka2025-39653749, author = {Heneka, M. T. and van der Flier, W. M. and Jessen, F. and Hoozemanns, J. and Thal, D. R. and Boche, D. and Brosseron, F. and Teunissen, C. and others}, title = {{Neuroinflammation in Alzheimer disease}}, journal = {Nature reviews. Immunology}, year = {2025}, doi = {10.1038/s41577-024-01104-7}, pmid = {39653749}, url = {https://doi.org/10.1038/s41577-024-01104-7} } @article{orkaby2016-28039854, author = {Orkaby, Ariela R. and Ozonoff, Al and Reisman, Joel I. and Miller, Donald Ray and Zhao, Shibei and Rose, Adam J.}, title = {{Continued Use of Warfarin in Veterans with Atrial Fibrillation After Dementia Diagnosis}}, journal = {Journal of the American Geriatrics Society}, year = {2016}, doi = {10.1111/jgs.14573}, pmid = {28039854}, url = {https://doi.org/10.1111/jgs.14573} } @article{levine2025-40062407, author = {Levine, Deborah A. and Whitney, Rachael T. and Ye, Wen and Briceño, Emily M. and Gross, Alden L. and Giordani, Bruno and Sussman, Jeremy B. and Lazar, Ronald M. and others}, title = {{Associations Between Stroke Type, Ischemic Stroke Subtypes, and Poststroke Cognitive Trajectories}}, journal = {Stroke}, year = {2025}, doi = {10.1161/strokeaha.124.047640}, pmid = {40062407}, url = {https://doi.org/10.1161/strokeaha.124.047640} } @article{graffradford2002-11939894, author = {Graff-Radford, N. R. and Green, R. C. and Go, R. C. and Hutton, M. L. and Edeki, T. and Bachman, D. and Adamson, J. L. and Griffith, P. and others}, title = {{Association between apolipoprotein E genotype and Alzheimer disease in African American subjects}}, journal = {Archives of neurology}, year = {2002}, doi = {10.1001/archneur.59.4.594}, pmid = {11939894}, url = {https://doi.org/10.1001/archneur.59.4.594} } @article{bondi2014-24844687, author = {Bondi, M. W. and Edmonds, E. C. and Jak, A. J. and Clark, L. R. and Delano-Wood, L. and McDonald, C. R. and Nation, D. A. and Libon, D. J. and others}, title = {{Neuropsychological criteria for mild cognitive impairment improves diagnostic precision, biomarker associations, and progression rates}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2014}, doi = {10.3233/jad-140276}, pmid = {24844687}, url = {https://doi.org/10.3233/jad-140276} } @article{tagge2018-29360998, author = {Tagge, C. A. and Fisher, A. M. and Minaeva, O. V. and Gaudreau-Balderrama, A. and Moncaster, J. A. and Zhang, X. L. and Wojnarowicz, M. W. and Casey, N. and others}, title = {{Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model}}, journal = {Brain : a journal of neurology}, year = {2018}, doi = {10.1093/brain/awx350}, pmid = {29360998}, url = {https://doi.org/10.1093/brain/awx350} } @article{albert2007-17402816, author = {Albert, M. and Blacker, D. and Moss, M. B. and Tanzi, R. and McArdle, J. J.}, title = {{Longitudinal change in cognitive performance among individuals with mild cognitive impairment}}, journal = {Neuropsychology}, year = {2007}, doi = {10.1037/0894-4105.21.2.158}, pmid = {17402816}, url = {https://doi.org/10.1037/0894-4105.21.2.158} } @article{ali2023-37101235, author = {Ali, M. and Archer, D. B. and Gorijala, P. and Western, D. and Timsina, J. and Fernández, M. V. and Wang, T. C. and Satizabal, C. L. and others}, title = {{Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease}}, journal = {Acta neuropathologica communications}, year = {2023}, doi = {10.1186/s40478-023-01563-4}, pmid = {37101235}, url = {https://doi.org/10.1186/s40478-023-01563-4} } @article{westwood2014-24706014, author = {Westwood, A. J. and Beiser, A. and Decarli, C. and Harris, T. B. and Chen, T. C. and He, X. M. and Roubenoff, R. and Pikula, A. and others}, title = {{Insulin-like growth factor-1 and risk of Alzheimer dementia and brain atrophy}}, journal = {Neurology}, year = {2014}, doi = {10.1212/wnl.0000000000000382}, pmid = {24706014}, url = {https://doi.org/10.1212/wnl.0000000000000382} } @article{christensen2008-18344711, author = {Christensen, K. D. and Roberts, J. S. and Royal, C. D. and Fasaye, G. A. and Obisesan, T. and Cupples, L. A. and Whitehouse, P. J. and Butson, M. B. and others}, title = {{Incorporating ethnicity into genetic risk assessment for Alzheimer disease: the REVEAL study experience}}, journal = {Genetics in medicine : official journal of the American College of Medical Genetics}, year = {2008}, doi = {10.1097/gim.0b013e318164e4cf}, pmid = {18344711}, url = {https://doi.org/10.1097/gim.0b013e318164e4cf} } @article{alber2019-31011621, author = {Alber, J. and Alladi, S. and Bae, H. J. and Barton, D. A. and Beckett, L. A. and Bell, J. M. and Berman, S. E. and Biessels, G. J. and others}, title = {{White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2019}, doi = {10.1016/j.trci.2019.02.001}, pmid = {31011621}, url = {https://doi.org/10.1016/j.trci.2019.02.001} } @article{fleisher2012-23137949, author = {Fleisher, A. S. and Chen, K. and Quiroz, Y. T. and Jakimovich, L. J. and Gomez, M. G. and Langois, C. M. and Langbaum, J. B. and Ayutyanont, N. and others}, title = {{Florbetapir PET analysis of amyloid-β deposition in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional study}}, journal = {The Lancet. Neurology}, year = {2012}, doi = {10.1016/s1474-4422(12)70227-2}, pmid = {23137949}, url = {https://doi.org/10.1016/s1474-4422(12)70227-2} } @article{gates2002-11943044, author = {Gates, G. A. and Beiser, A. and Rees, T. S. and D'Agostino, R. B. and Wolf, P. A.}, title = {{Central auditory dysfunction may precede the onset of clinical dementia in people with probable Alzheimer's disease}}, journal = {Journal of the American Geriatrics Society}, year = {2002}, doi = {10.1046/j.1532-5415.2002.50114.x}, pmid = {11943044}, url = {https://doi.org/10.1046/j.1532-5415.2002.50114.x} } @article{ko2025-39680399, author = {Ko, D. and Chung, M. K. and Evans, P. T. and Benjamin, E. J. and Helm, R. H.}, title = {{Atrial Fibrillation: A Review}}, journal = {JAMA}, year = {2025}, doi = {10.1001/jama.2024.22451}, pmid = {39680399}, url = {https://doi.org/10.1001/jama.2024.22451} } @article{kalaria2024-38696263, author = {Kalaria, R. and Maestre, G. and Mahinrad, S. and Acosta, D. M. and Akinyemi, R. O. and Alladi, S. and Allegri, R. F. and Arshad, F. and others}, title = {{The 2022 symposium on dementia and brain aging in low- and middle-income countries: Highlights on research, diagnosis, care, and impact}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.13836}, pmid = {38696263}, url = {https://doi.org/10.1002/alz.13836} } @article{wu2017-28497805, author = {Wu, Y. T. and Beiser, A. S. and Breteler, M. M. B. and Fratiglioni, L. and Helmer, C. and Hendrie, H. C. and Honda, H. and Ikram, M. A. and others}, title = {{The changing prevalence and incidence of dementia over time - current evidence}}, journal = {Nature reviews. Neurology}, year = {2017}, doi = {10.1038/nrneurol.2017.63}, pmid = {28497805}, url = {https://doi.org/10.1038/nrneurol.2017.63} } @article{solomon2009-19648749, author = {Solomon, A. and Kivipelto, M. and Wolozin, B. and Zhou, J. and Whitmer, R. A.}, title = {{Midlife serum cholesterol and increased risk of Alzheimer's and vascular dementia three decades later}}, journal = {Dementia and geriatric cognitive disorders}, year = {2009}, doi = {10.1159/000231980}, pmid = {19648749}, url = {https://doi.org/10.1159/000231980} } @article{amini2024-38924662, author = {Amini, S. and Hao, B. and Yang, J. and Karjadi, C. and Kolachalama, V. B. and Au, R. and Paschalidis, I. C.}, title = {{Prediction of Alzheimer's disease progression within 6 years using speech: A novel approach leveraging language models}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.13886}, pmid = {38924662}, url = {https://doi.org/10.1002/alz.13886} } @article{wolozin2007-17640385, author = {Wolozin, B. and Wang, S. W. and Li, N. C. and Lee, A. and Lee, T. A. and Kazis, L. E.}, title = {{Simvastatin is associated with a reduced incidence of dementia and Parkinson's disease}}, journal = {BMC medicine}, year = {2007}, doi = {10.1186/1741-7015-5-20}, pmid = {17640385}, url = {https://doi.org/10.1186/1741-7015-5-20} } @article{tschanz2011-21606896, author = {Tschanz, J. T. and Corcoran, C. D. and Schwartz, S. and Treiber, K. and Green, R. C. and Norton, M. C. and Mielke, M. M. and Piercy, K. and others}, title = {{Progression of cognitive, functional, and neuropsychiatric symptom domains in a population cohort with Alzheimer dementia: the Cache County Dementia Progression study}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2011}, doi = {10.1097/jgp.0b013e3181faec23}, pmid = {21606896}, url = {https://doi.org/10.1097/jgp.0b013e3181faec23} } @article{barnes2014-24491321, author = {Barnes, D. E. and Beiser, A. S. and Lee, A. and Langa, K. M. and Koyama, A. and Preis, SR. and Neuhaus, J. and McCammon, R. J. and others}, title = {{Development and validation of a brief dementia screening indicator for primary care}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2014}, doi = {10.1016/j.jalz.2013.11.006}, pmid = {24491321}, url = {https://doi.org/10.1016/j.jalz.2013.11.006} } @article{weinstein2015-25948725, author = {Weinstein, G. and Maillard, P. and Himali, J. J. and Beiser, A. S. and Au, R. and Wolf, P. A. and Seshadri, S. and DeCarli, C.}, title = {{Glucose indices are associated with cognitive and structural brain measures in young adults}}, journal = {Neurology}, year = {2015}, doi = {10.1212/wnl.0000000000001655}, pmid = {25948725}, url = {https://doi.org/10.1212/wnl.0000000000001655} } @article{seshadri2004-15534241, author = {Seshadri, S. and Wolf, P. A. and Beiser, A. and Elias, M. F. and Au, R. and Kase, C. S. and D'Agostino, R. B. and DeCarli, C.}, title = {{Stroke risk profile, brain volume, and cognitive function: the Framingham Offspring Study}}, journal = {Neurology}, year = {2004}, doi = {10.1212/01.wnl.0000142968.22691.70}, pmid = {15534241}, url = {https://doi.org/10.1212/01.wnl.0000142968.22691.70} } @article{kunkle2025-41437928, author = {Kunkle, Brian W. and Gomez, Lissette and Tosto, Giuseppe and Rodriguez, Omar Garcia and Slifer, Susan H. and Hamilton‐Nelson, Kara L. and Naj, Adam Christian and Kushch, Nicholas A. and others}, title = {{Novel sex‐specific candidate loci associated with Alzheimer disease identified through sex‐aware multi‐ancestry genome‐wide meta‐analysis}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz70855_106407}, pmid = {41437928}, url = {https://doi.org/10.1002/alz70855_106407} } @article{li2026-41535386, author = {Li, Jun and Hu, Jie and Yun, Huan and Mei, Zhendong and Wang, Xingyan and Luo, Kai and Guasch‐Ferré, Marta and Han, Xikun and others}, title = {{Circulating metabolites, genetics and lifestyle factors in relation to future risk of type 2 diabetes}}, journal = {Nature Medicine}, year = {2026}, doi = {10.1038/s41591-025-04105-8}, pmid = {41535386}, url = {https://doi.org/10.1038/s41591-025-04105-8} } @article{cruchaga2013-23562540, author = {Cruchaga, Carlos C and Kauwe, John S. K. and Harari, Oscar and Jin, Sheng Chih and Cai, Yefei and Karch, Celeste M M. and Benítez, Bruno A. and Jeng, Amanda T. and Skorupa, Tara and Carrell, David and Bertelsen, Sarah E. and Bailey, Matthew H. and McKean, David M. and Shulman, Joshua M and De Jager, Philip L. and Chibnik, Lori Beth and Bennett, David and Arnold, S. E. and Harold, Denise H. and Sims, Rebecca and Gerrish, Amy and Williams, Julie H. and Van Deerlin, Vivianna M. and Lee, Virginia M.‐Y. and Shaw, Leslie M. and Trojanowski, John Q. and Haines, Jonathan L. and Mayeux, Richard P and Pericak‐Vance, Margaret A. and Farrer, Lindsay A. and Schellenberg, Gerard D. and Peskind, Elaine R. and Galasko, Douglas R and Fagan, Anne M. and Holtzman, David M. and Morris, John C. and Goate, Alison}, title = {{GWAS of Cerebrospinal Fluid Tau Levels Identifies Risk Variants for Alzheimer’s Disease}}, journal = {Neuron}, year = {2013}, doi = {10.1016/j.neuron.2013.02.026}, pmid = {23562540}, url = {https://doi.org/10.1016/j.neuron.2013.02.026} } @article{kurniansyah2026-42661068, author = {Kurniansyah, N. and Tasaki, S. and Rehman, H. and Zhu, C. and Farrell, J. and Sherva, R. and Hauger, R. and Merritt, V. C. and Panizzon, M. and Zhang, R. and Gaziano, J. M. and Gim, J. and others}, title = {{A multiancestry polygenic risk score for Alzheimer's disease is associated with cognitive decline and neuropathological hallmarks in diverse populations}}, journal = {Nature genetics}, year = {2026}, doi = {10.1038/s41588-026-02722-8}, pmid = {42661068}, url = {https://doi.org/10.1038/s41588-026-02722-8} } @article{desikan2017-28323831, author = {Desikan, R. S. and Fan, C. C. and Wang, Y. and Schork, A. J. and Cabral, H. J. and Cupples, L. A. and Thompson, W. K. and Besser, L. and others}, title = {{Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score}}, journal = {PLoS medicine}, year = {2017}, doi = {10.1371/journal.pmed.1002258}, pmid = {28323831}, url = {https://doi.org/10.1371/journal.pmed.1002258} } @article{schaefer2006-17101822, author = {Schaefer, E. J. and Bongard, V. and Beiser, A. S. and Lamon-Fava, S. and Robins, S. J. and Au, R. and Tucker, K. L. and Kyle, D. J. and others}, title = {{Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: the Framingham Heart Study}}, journal = {Archives of neurology}, year = {2006}, doi = {10.1001/archneur.63.11.1545}, pmid = {17101822}, url = {https://doi.org/10.1001/archneur.63.11.1545} } @article{gavett2010-20587081, author = {Gavett, B. E. and Stern, R. A. and Cantu, R. C. and Nowinski, C. J. and McKee, A. C.}, title = {{Mild traumatic brain injury: a risk factor for neurodegeneration}}, journal = {Alzheimer's research \& therapy}, year = {2010}, doi = {10.1186/alzrt42}, pmid = {20587081}, url = {https://doi.org/10.1186/alzrt42} } @article{pase2017-28428346, author = {Pase, M. P. and Himali, J. J. and Beiser, A. S. and Aparicio, H. J. and Satizabal, C. L. and Vasan, R. S. and Seshadri, S. and Jacques, P. F.}, title = {{Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia: A Prospective Cohort Study}}, journal = {Stroke}, year = {2017}, doi = {10.1161/strokeaha.116.016027}, pmid = {28428346}, url = {https://doi.org/10.1161/strokeaha.116.016027} } @article{weller2018-30135715, author = {Weller, J. and Budson, A.}, title = {{Current understanding of Alzheimer's disease diagnosis and treatment}}, journal = {F1000Research}, year = {2018}, doi = {10.12688/f1000research.14506.1}, pmid = {30135715}, url = {https://doi.org/10.12688/f1000research.14506.1} } @article{jefferson2007-17389308, author = {Jefferson, A. L. and Massaro, J. M. and Wolf, P. A. and Seshadri, S. and Au, R. and Vasan, R. S. and Larson, M. G. and Meigs, J. B. and others}, title = {{Inflammatory biomarkers are associated with total brain volume: the Framingham Heart Study}}, journal = {Neurology}, year = {2007}, doi = {10.1212/01.wnl.0000257815.20548.df}, pmid = {17389308}, url = {https://doi.org/10.1212/01.wnl.0000257815.20548.df} } @article{gendron2013-24129584, author = {Gendron, T. F. and Bieniek, K. F. and Zhang, Y. J. and Jansen-West, K. and Ash, P. E. and Caulfield, T. and Daughrity, L. and Dunmore, J. H. and others}, title = {{Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS}}, journal = {Acta neuropathologica}, year = {2013}, doi = {10.1007/s00401-013-1192-8}, pmid = {24129584}, url = {https://doi.org/10.1007/s00401-013-1192-8} } @article{reinhart2019-30962628, author = {Reinhart, R. M. G. and Nguyen, J. A.}, title = {{Working memory revived in older adults by synchronizing rhythmic brain circuits}}, journal = {Nature neuroscience}, year = {2019}, doi = {10.1038/s41593-019-0371-x}, pmid = {30962628}, url = {https://doi.org/10.1038/s41593-019-0371-x} } @article{kunkle2017-28738127, author = {Kunkle, B. W. and Vardarajan, B. N. and Naj, A. C. and Whitehead, P. L. and Rolati, S. and Slifer, S. and Carney, R. M. and Cuccaro, M. L. and others}, title = {{Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport}}, journal = {JAMA neurology}, year = {2017}, doi = {10.1001/jamaneurol.2017.1518}, pmid = {28738127}, url = {https://doi.org/10.1001/jamaneurol.2017.1518} } @article{edmonds2015-24857234, author = {Edmonds, E. C. and Delano-Wood, L. and Clark, L. R. and Jak, A. J. and Nation, D. A. and McDonald, C. R. and Libon, D. J. and Au, R. and others}, title = {{Susceptibility of the conventional criteria for mild cognitive impairment to false-positive diagnostic errors}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2015}, doi = {10.1016/j.jalz.2014.03.005}, pmid = {24857234}, url = {https://doi.org/10.1016/j.jalz.2014.03.005} } @article{pase2017-28835407, author = {Pase, M. P. and Himali, J. J. and Grima, N. A. and Beiser, A. S. and Satizabal, C. L. and Aparicio, H. J. and Thomas, R. J. and Gottlieb, D. J. and others}, title = {{Sleep architecture and the risk of incident dementia in the community}}, journal = {Neurology}, year = {2017}, doi = {10.1212/wnl.0000000000004373}, pmid = {28835407}, url = {https://doi.org/10.1212/wnl.0000000000004373} } @article{pase2016-27073239, author = {Pase, M. P. and Beiser, A. and Enserro, D. and Xanthakis, V. and Aparicio, H. and Satizabal, C. L. and Himali, J. J. and Kase, C. S. and others}, title = {{Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia}}, journal = {Stroke}, year = {2016}, doi = {10.1161/strokeaha.115.012608}, pmid = {27073239}, url = {https://doi.org/10.1161/strokeaha.115.012608} } @article{peloso2020-32690788, author = {Peloso, G. M. and Beiser, A. S. and Satizabal, C. L. and Xanthakis, V. and Vasan, R. S. and Pase, M. P. and Destefano, A. L. and Seshadri, S.}, title = {{Cardiovascular health, genetic risk, and risk of dementia in the Framingham Heart Study}}, journal = {Neurology}, year = {2020}, doi = {10.1212/wnl.0000000000010306}, pmid = {32690788}, url = {https://doi.org/10.1212/wnl.0000000000010306} } @article{romero2022-36175148, author = {Romero, JR. and Pinheiro, A. and Aparicio, H. J. and DeCarli, C. S. and Demissie, S. and Seshadri, S.}, title = {{MRI-Visible Perivascular Spaces and Risk of Incident Dementia: The Framingham Heart Study}}, journal = {Neurology}, year = {2022}, doi = {10.1212/wnl.0000000000201293}, pmid = {36175148}, url = {https://doi.org/10.1212/wnl.0000000000201293} } @article{spartano2019-31660424, author = {Spartano, N. L. and Demissie, S. and Himali, J. J. and Dukes, K. A. and Murabito, J. M. and Vasan, R. S. and Beiser, A. S. and Seshadri, S.}, title = {{Accelerometer-determined physical activity and cognitive function in middle-aged and older adults from two generations of the Framingham Heart Study}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2019}, doi = {10.1016/j.trci.2019.08.007}, pmid = {31660424}, url = {https://doi.org/10.1016/j.trci.2019.08.007} } @article{francis2025-40824575, author = {Francis, Lily and Seshadri, Sudha S. and Dillard, Lauren K. and Kujawa, Sharon G. and Welling, D. Bradley and Alcabes, Richard L. and Beiser, Alexa S.}, title = {{Self-Reported Hearing Aid Use and Risk of Incident Dementia}}, journal = {JAMA Neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.2713}, pmid = {40824575}, url = {https://doi.org/10.1001/jamaneurol.2025.2713} } @article{lioutas2025-40611491, author = {Lioutas, Vasileios‐Arsenios and Peloso, Gina Marie and Romero, Jose Rafael and Aparicio, Hugo Javier and Gonzales, Mitzi M. and Werry, Amy E. and Himali, Dibya and Himali, Jayandra Jung and others}, title = {{Long‐Term Incidence of Dementia Following Transient Ischemic Attack: A Longitudinal Cohort Study}}, journal = {Journal of the American Heart Association}, year = {2025}, doi = {10.1161/jaha.124.037817}, pmid = {40611491}, url = {https://doi.org/10.1161/jaha.124.037817} } @article{chen2025-40531522, author = {Chen, Hui and Ding, Yihong and Dhana, Klodian and Agarwal, Puja and Beck, Todd L. and Rajan, Kumar Bharat and van Lent, Debora Melo and Ma, Yuan and others}, title = {{Sweetened Beverages and Incident All-Cause Dementia Among Older Adults}}, journal = {JAMA Psychiatry}, year = {2025}, doi = {10.1001/jamapsychiatry.2025.1230}, pmid = {40531522}, url = {https://doi.org/10.1001/jamapsychiatry.2025.1230} } @article{debette2010-20660506, author = {Debette, Stéphanie and Markus, Hugh Stephen}, title = {{The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis}}, journal = {BMJ}, year = {2010}, doi = {10.1136/bmj.c3666}, pmid = {20660506}, url = {https://doi.org/10.1136/bmj.c3666} } @article{rajan2021-34043283, author = {Rajan, Kumar Bharat and Weuve, Jennifer and Barnes, Lisa Laverne and McAninch, Elizabeth A. and Wilson, Robert Smith and Evans, Denis A.}, title = {{Population estimate of people with clinical Alzheimer's disease and mild cognitive impairment in the United States (2020–2060)}}, journal = {Alzheimer s \& Dementia}, year = {2021}, doi = {10.1002/alz.12362}, pmid = {34043283}, url = {https://doi.org/10.1002/alz.12362} } @article{wu2026-42427166, author = {Wu, Y. and Rojas-Saunero, L. P. and Zhou, Y. and Hayes-Larson, E. and Fong, J. O. and Mobley, T. and Brenowitz, W. D. and Hoffmann, T. J. and Deters, K. D. and Whitmer, R. A. and Gilsanz, P. and Gee, G. C. and others}, title = {{APOE-ε4 carriership and dementia risk over 10 years among Asian American and White older adults}}, journal = {Alzheimer's \& Dementia}, year = {2026}, doi = {10.1002/alz.71615}, pmid = {42427166}, url = {https://doi.org/10.1002/alz.71615} } @article{quiroz2015-26121081, author = {Quiroz, Y. T. and Schultz, A. P. and Chen, K. and Protas, H. D. and Brickhouse, M. and Fleisher, A. S. and Langbaum, J. B. and Thiyyagura, P. and others}, title = {{Brain Imaging and Blood Biomarker Abnormalities in Children With Autosomal Dominant Alzheimer Disease: A Cross-Sectional Study}}, journal = {JAMA neurology}, year = {2015}, doi = {10.1001/jamaneurol.2015.1099}, pmid = {26121081}, url = {https://doi.org/10.1001/jamaneurol.2015.1099} } @article{green2002-11790212, author = {Green, R. C. and Cupples, L. A. and Go, R. and Benke, K. S. and Edeki, T. and Griffith, P. A. and Williams, M. and Hipps, Y. and others}, title = {{Risk of dementia among white and African American relatives of patients with Alzheimer disease}}, journal = {JAMA}, year = {2002}, doi = {10.1001/jama.287.3.329}, pmid = {11790212}, url = {https://doi.org/10.1001/jama.287.3.329} } @article{tan2003-12742802, author = {Tan, Z. S. and Seshadri, S. and Beiser, A. and Wilson, P. W. and Kiel, D. P. and Tocco, M. and D'Agostino, R. B. and Wolf, P. A.}, title = {{Plasma total cholesterol level as a risk factor for Alzheimer disease: the Framingham Study}}, journal = {Archives of internal medicine}, year = {2003}, doi = {10.1001/archinte.163.9.1053}, pmid = {12742802}, url = {https://doi.org/10.1001/archinte.163.9.1053} } @article{mielke2022-35394117, author = {Mielke, M. M. and Aggarwal, N. T. and Vila-Castelar, C. and Agarwal, P. and Arenaza-Urquijo, E. M. and Brett, B. and Brugulat-Serrat, A. and DuBose, L. E. and others}, title = {{Consideration of sex and gender in Alzheimer's disease and related disorders from a global perspective}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2022}, doi = {10.1002/alz.12662}, pmid = {35394117}, url = {https://doi.org/10.1002/alz.12662} } @article{elias2000-10867777, author = {Elias, M. F. and Beiser, A. and Wolf, P. A. and Au, R. and White, R. F. and D'Agostino, R. B.}, title = {{The preclinical phase of alzheimer disease: A 22-year prospective study of the Framingham Cohort}}, journal = {Archives of neurology}, year = {2000}, doi = {10.1001/archneur.57.6.808}, pmid = {10867777}, url = {https://doi.org/10.1001/archneur.57.6.808} } @article{bachman1992-1734291, author = {Bachman, D. L. and Wolf, P. A. and Linn, R. and Knoefel, J. E. and Cobb, J. and Belanger, A. and D'Agostino, R. B. and White, L. R.}, title = {{Prevalence of dementia and probable senile dementia of the Alzheimer type in the Framingham Study}}, journal = {Neurology}, year = {1992}, doi = {10.1212/wnl.42.1.115}, pmid = {1734291}, url = {https://doi.org/10.1212/wnl.42.1.115} } @article{amini2023-35796399, author = {Amini, S. and Hao, B. and Zhang, L. and Song, M. and Gupta, A. and Karjadi, C. and Kolachalama, V. B. and Au, R. and others}, title = {{Automated detection of mild cognitive impairment and dementia from voice recordings: A natural language processing approach}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2023}, doi = {10.1002/alz.12721}, pmid = {35796399}, url = {https://doi.org/10.1002/alz.12721} } @article{xue2021-34465384, author = {Xue, C. and Karjadi, C. and Paschalidis, I. C. and Au, R. and Kolachalama, V. B.}, title = {{Detection of dementia on voice recordings using deep learning: a Framingham Heart Study}}, journal = {Alzheimer's research \& therapy}, year = {2021}, doi = {10.1186/s13195-021-00888-3}, pmid = {34465384}, url = {https://doi.org/10.1186/s13195-021-00888-3} } @article{wolozin2019-31582840, author = {Wolozin, B. and Ivanov, P.}, title = {{Stress granules and neurodegeneration}}, journal = {Nature reviews. Neuroscience}, year = {2019}, doi = {10.1038/s41583-019-0222-5}, pmid = {31582840}, url = {https://doi.org/10.1038/s41583-019-0222-5} } @article{liuyesucevitz2010-20948999, author = {Liu-Yesucevitz, L. and Bilgutay, A. and Zhang, Y. J. and Vanderweyde, T. and Citro, A. and Mehta, T. and Zaarur, N. and McKee, A. and others}, title = {{Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue}}, journal = {PloS one}, year = {2010}, doi = {10.1371/journal.pone.0013250}, pmid = {20948999}, url = {https://doi.org/10.1371/journal.pone.0013250} } @article{patel2019-30924900, author = {Patel, D. and Mez, J. and Vardarajan, B. N. and Staley, L. and Chung, J. and Zhang, X. and Farrell, J. J. and Rynkiewicz, M. J. and others}, title = {{Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry}}, journal = {JAMA network open}, year = {2019}, doi = {10.1001/jamanetworkopen.2019.1350}, pmid = {30924900}, url = {https://doi.org/10.1001/jamanetworkopen.2019.1350} } @article{turk2022-35139894, author = {Turk, K. W. and Geada, A. and Alvarez, V. E. and Xia, W. and Cherry, J. D. and Nicks, R. and Meng, G. and Daley, S. and others}, title = {{A comparison between tau and amyloid-β cerebrospinal fluid biomarkers in chronic traumatic encephalopathy and Alzheimer disease}}, journal = {Alzheimer's research \& therapy}, year = {2022}, doi = {10.1186/s13195-022-00976-y}, pmid = {35139894}, url = {https://doi.org/10.1186/s13195-022-00976-y} } @article{akhterkhan2021-33760348, author = {Akhter-Khan, S. C. and Tao, Q. and Ang, T. F. A. and Itchapurapu, I. S. and Alosco, M. L. and Mez, J. and Piers, R. J. and Steffens, D. C. and others}, title = {{Associations of loneliness with risk of Alzheimer's disease dementia in the Framingham Heart Study}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2021}, doi = {10.1002/alz.12327}, pmid = {33760348}, url = {https://doi.org/10.1002/alz.12327} } @article{nishtala2018-28943482, author = {Nishtala, A. and Piers, R. J. and Himali, J. J. and Beiser, A. S. and Davis-Plourde, K. L. and Saczynski, J. S. and McManus, D. D. and Benjamin, E. J. and others}, title = {{Atrial fibrillation and cognitive decline in the Framingham Heart Study}}, journal = {Heart rhythm}, year = {2018}, doi = {10.1016/j.hrthm.2017.09.036}, pmid = {28943482}, url = {https://doi.org/10.1016/j.hrthm.2017.09.036} } @article{seshadri2011-21255742, author = {Seshadri, S. and Beiser, A. and Au, R. and Wolf, P. A. and Evans, D. A. and Wilson, R. S. and Petersen, R. C. and Knopman, D. S. and others}, title = {{Operationalizing diagnostic criteria for Alzheimer's disease and other age-related cognitive impairment-Part 2}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2011}, doi = {10.1016/j.jalz.2010.12.002}, pmid = {21255742}, url = {https://doi.org/10.1016/j.jalz.2010.12.002} } @article{stgeorgehyslop1990-2395471, author = {St George-Hyslop, P. H. and Haines, J. L. and Farrer, L. A. and Polinsky, R. and Van Broeckhoven, C. and Goate, A. and McLachlan, D. R. and Orr, H. and others}, title = {{Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder}}, journal = {Nature}, year = {1990}, doi = {10.1038/347194a0}, pmid = {2395471}, url = {https://doi.org/10.1038/347194a0} } @article{cherry2016-27793189, author = {Cherry, J. D. and Tripodis, Y. and Alvarez, V. E. and Huber, B. and Kiernan, P. T. and Daneshvar, D. H. and Mez, J. and Montenigro, P. H. and others}, title = {{Microglial neuroinflammation contributes to tau accumulation in chronic traumatic encephalopathy}}, journal = {Acta neuropathologica communications}, year = {2016}, doi = {10.1186/s40478-016-0382-8}, pmid = {27793189}, url = {https://doi.org/10.1186/s40478-016-0382-8} } @article{derington2025-39945185, author = {Derington, Catherine G. and Berchie, Ransmond O. and Scharfstein, Daniel O. and Andrews, Ryan M. and Greene, Tom and Xu, Yizhe and King, Jordan B. and Supiano, Mark A. and others}, title = {{Effect of Initiation and Continuous Adherence to ARBs Versus ACEIs on Risk of Adjudicated Mild Cognitive Impairment or Dementia}}, journal = {The Journals of Gerontology Series A}, year = {2025}, doi = {10.1093/gerona/glaf028}, pmid = {39945185}, url = {https://doi.org/10.1093/gerona/glaf028} } @article{krishnan2026-42389671, author = {Krishnan, Laya and Gunasekaran, Gaurie and Dhore, Tamanna and Lauinger, Alexa and Kolachalama, Vijaya and Pappu, Suguna}, title = {{Leveraging artificial intelligence for analysis of the gut microbiome for dementia diagnosis: a scoping review and discussion}}, journal = {Frontiers in Dementia}, year = {2026}, doi = {10.3389/frdem.2026.1865441}, pmid = {42389671}, url = {https://doi.org/10.3389/frdem.2026.1865441} } @article{gallee2025-40990522, author = {Gallée, Jeanne and Gibbons, Laura E. and Choi, Seo‐Eun and Lee, Michael L. and Scollard, Phoebe and Trittschuh, Emily H. and Mez, Jesse and Saykin, Andrew J. and others}, title = {{Facets of language performance in early‐onset and late‐onset Alzheimer's disease dementia}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70705}, pmid = {40990522}, url = {https://doi.org/10.1002/alz.70705} } @article{cukier2016-27231719, author = {Cukier, H. N. and Kunkle, B. W. and Vardarajan, B. N. and Rolati, S. and Hamilton-Nelson, K. L. and Kohli, M. A. and Whitehead, P. L. and Dombroski, B. A. and others}, title = {{ABCA7 frameshift deletion associated with Alzheimer disease in African Americans}}, journal = {Neurology. Genetics}, year = {2016}, doi = {10.1212/nxg.0000000000000079}, pmid = {27231719}, url = {https://doi.org/10.1212/nxg.0000000000000079} } @article{barral2012-22539578, author = {Barral, S. and Bird, T. and Goate, A. and Farlow, M. R. and Diaz-Arrastia, R. and Bennett, D. A. and Graff-Radford, N. and Boeve, B. F. and others}, title = {{Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e3182553c48}, pmid = {22539578}, url = {https://doi.org/10.1212/wnl.0b013e3182553c48} } @article{perneczky2010-20625166, author = {Perneczky, R. and Wagenpfeil, S. and Lunetta, K. L. and Cupples, L. A. and Green, R. C. and Decarli, C. and Farrer, L. A. and Kurz, A. and others}, title = {{Head circumference, atrophy, and cognition: implications for brain reserve in Alzheimer disease}}, journal = {Neurology}, year = {2010}, doi = {10.1212/wnl.0b013e3181e7ca97}, pmid = {20625166}, url = {https://doi.org/10.1212/wnl.0b013e3181e7ca97} } @article{jefferson2011-21880293, author = {Jefferson, A. L. and Himali, J. J. and Au, R. and Seshadri, S. and Decarli, C. and O'Donnell, C. J. and Wolf, P. A. and Manning, W. J. and others}, title = {{Relation of left ventricular ejection fraction to cognitive aging (from the Framingham Heart Study)}}, journal = {The American journal of cardiology}, year = {2011}, doi = {10.1016/j.amjcard.2011.06.056}, pmid = {21880293}, url = {https://doi.org/10.1016/j.amjcard.2011.06.056} } @article{debette2009-20007524, author = {Debette, S. and Wolf, P. A. and Beiser, A. and Au, R. and Himali, J. J. and Pikula, A. and Auerbach, S. and others}, title = {{Association of parental dementia with cognitive and brain MRI measures in middle-aged adults}}, journal = {Neurology}, year = {2009}, doi = {10.1212/wnl.0b013e3181c67833}, pmid = {20007524}, url = {https://doi.org/10.1212/wnl.0b013e3181c67833} } @article{harper2001-11296096, author = {Harper, D. G. and Stopa, E. G. and McKee, A. C. and Satlin, A. and Harlan, P. C. and Goldstein, R. and Volicer, L.}, title = {{Differential circadian rhythm disturbances in men with Alzheimer disease and frontotemporal degeneration}}, journal = {Archives of general psychiatry}, year = {2001}, doi = {10.1001/archpsyc.58.4.353}, pmid = {11296096}, url = {https://doi.org/10.1001/archpsyc.58.4.353} } @article{weiner2010-20451868, author = {Weiner, M. W. and Aisen, P. S. and Jack, C. R. and Jagust, W. J. and Trojanowski, J. Q. and Shaw, L. and Saykin, A. J. and Morris, J. C. and others}, title = {{The Alzheimer's disease neuroimaging initiative: progress report and future plans}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2010}, doi = {10.1016/j.jalz.2010.03.007}, pmid = {20451868}, url = {https://doi.org/10.1016/j.jalz.2010.03.007} } @article{muraoka2020-32854315, author = {Muraoka, S. and Jedrychowski, M. P. and Yanamandra, K. and Ikezu, S. and Gygi, S. P. and Ikezu, T.}, title = {{Proteomic Profiling of Extracellular Vesicles Derived from Cerebrospinal Fluid of Alzheimer's Disease Patients: A Pilot Study}}, journal = {Cells}, year = {2020}, doi = {10.3390/cells9091959}, pmid = {32854315}, url = {https://doi.org/10.3390/cells9091959} } @article{atwood2004-15143299, author = {Atwood, L. D. and Wolf, P. A. and Heard-Costa, N. L. and Massaro, J. M. and Beiser, A. and D'Agostino, R. B. and DeCarli, C.}, title = {{Genetic variation in white matter hyperintensity volume in the Framingham Study}}, journal = {Stroke}, year = {2004}, doi = {10.1161/01.str.0000129643.77045.10}, pmid = {15143299}, url = {https://doi.org/10.1161/01.str.0000129643.77045.10} } @article{berry2007-17923597, author = {Berry, S. D. and Samelson, E. J. and Hannan, M. T. and McLean, R. R. and Lu, M. and Cupples, L. A. and Shaffer, M. L. and Beiser, A. L. and others}, title = {{Second hip fracture in older men and women: the Framingham Study}}, journal = {Archives of internal medicine}, year = {2007}, doi = {10.1001/archinte.167.18.1971}, pmid = {17923597}, url = {https://doi.org/10.1001/archinte.167.18.1971} } @article{karakis2016-26890771, author = {Karakis, I. and Pase, M. P. and Beiser, A. and Booth, S. L. and Jacques, P. F. and Rogers, G. and DeCarli, C. and Vasan, R. S. and others}, title = {{Association of Serum Vitamin D with the Risk of Incident Dementia and Subclinical Indices of Brain Aging: The Framingham Heart Study}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2016}, doi = {10.3233/jad-150991}, pmid = {26890771}, url = {https://doi.org/10.3233/jad-150991} } @article{melovanlent2021-34092629, author = {Melo van Lent, D. and O'Donnell, A. and Beiser, A. S. and Vasan, R. S. and DeCarli, C. S. and Scarmeas, N. and Wagner, M. and Jacques, P. F. and others}, title = {{Mind Diet Adherence and Cognitive Performance in the Framingham Heart Study}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2021}, doi = {10.3233/jad-201238}, pmid = {34092629}, url = {https://doi.org/10.3233/jad-201238} } @article{tong2024-39444005, author = {Tong, T. and Zhu, C. and Farrell, J. J. and Khurshid, Z. and {Alzheimer’s Disease Sequencing Project} and {Alzheimer’s Disease Neuroimaging Initiative} and Martin, E. R. and Pericak-Vance, M. A. and others}, title = {{Blood-derived mitochondrial DNA copy number is associated with Alzheimer disease, Alzheimer-related biomarkers and serum metabolites}}, journal = {Alzheimer's research \& therapy}, year = {2024}, doi = {10.1186/s13195-024-01601-w}, pmid = {39444005}, url = {https://doi.org/10.1186/s13195-024-01601-w} } @article{younes2025-40145384, author = {Younes, K. and Johns, E. and Young, C. B. and Kennedy, G. and Mukherjee, S. and Vossler, H. A. and Winer, J. and Cody, K. and others}, title = {{Amyloid PET predicts longitudinal functional and cognitive trajectories in a heterogeneous cohort}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.70075}, pmid = {40145384}, url = {https://doi.org/10.1002/alz.70075} } @article{jun2017-28183528, author = {Jun, G. R. and Chung, J. and Mez, J. and Barber, R. and Beecham, G. W. and Bennett, D. A. and Buxbaum, J. D. and Byrd, G. S. and others}, title = {{Transethnic genome-wide scan identifies novel Alzheimer's disease loci}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2017}, doi = {10.1016/j.jalz.2016.12.012}, pmid = {28183528}, url = {https://doi.org/10.1016/j.jalz.2016.12.012} } @article{adams2018-30053297, author = {Adams, J. W. and Alvarez, V. E. and Mez, J. and Huber, B. R. and Tripodis, Y. and Xia, W. and Meng, G. and Kubilus, C. A. and others}, title = {{Lewy Body Pathology and Chronic Traumatic Encephalopathy Associated With Contact Sports}}, journal = {Journal of neuropathology and experimental neurology}, year = {2018}, doi = {10.1093/jnen/nly065}, pmid = {30053297}, url = {https://doi.org/10.1093/jnen/nly065} } @article{staerk2017-28450367, author = {Staerk, L. and Sherer, J. A. and Ko, D. and Benjamin, E. J. and Helm, R. H.}, title = {{Atrial Fibrillation: Epidemiology, Pathophysiology, and Clinical Outcomes}}, journal = {Circulation research}, year = {2017}, doi = {10.1161/circresaha.117.309732}, pmid = {28450367}, url = {https://doi.org/10.1161/circresaha.117.309732} } @article{zlokovic2020-33030307, author = {Zlokovic, B. V. and Gottesman, R. F. and Bernstein, K. E. and Seshadri, S. and McKee, A. and Snyder, H. and Greenberg, S. M. and Yaffe, K. and others}, title = {{Vascular contributions to cognitive impairment and dementia (VCID): A report from the 2018 National Heart, Lung, and Blood Institute and National Institute of Neurological Disorders and Stroke Workshop}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2020}, doi = {10.1002/alz.12157}, pmid = {33030307}, url = {https://doi.org/10.1002/alz.12157} } @article{gates1996-8630210, author = {Gates, G. A. and Cobb, J. L. and Linn, R. T. and Rees, T. and Wolf, P. A. and D'Agostino, R. B.}, title = {{Central auditory dysfunction, cognitive dysfunction, and dementia in older people}}, journal = {Archives of otolaryngology--head \& neck surgery}, year = {1996}, doi = {10.1001/archotol.1996.01890140047010}, pmid = {8630210}, url = {https://doi.org/10.1001/archotol.1996.01890140047010} } @article{study2017-29234814, author = {{US Preventive Services Task Force} and Grossman, D. C. and Curry, S. J. and Owens, D. K. and Barry, M. J. and Davidson, K. W. and Doubeni, C. A. and Epling, J. W. and others}, title = {{Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Women: US Preventive Services Task Force Recommendation Statement}}, journal = {JAMA}, year = {2017}, doi = {10.1001/jama.2017.18261}, pmid = {29234814}, url = {https://doi.org/10.1001/jama.2017.18261} } @article{elias2003-12587008, author = {Elias, M. F. and Elias, P. K. and Sullivan, L. M. and Wolf, P. A. and D'Agostino, R. B.}, title = {{Lower cognitive function in the presence of obesity and hypertension: the Framingham heart study}}, journal = {International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity}, year = {2003}, doi = {10.1038/sj.ijo.802225}, pmid = {12587008}, url = {https://doi.org/10.1038/sj.ijo.802225} } @article{mckee2009-19535999, author = {McKee, A. C. and Cantu, R. C. and Nowinski, C. J. and Hedley-Whyte, E. T. and Gavett, B. E. and Budson, A. E. and Santini, V. E. and Lee, H. S. and others}, title = {{Chronic traumatic encephalopathy in athletes: progressive tauopathy after repetitive head injury}}, journal = {Journal of neuropathology and experimental neurology}, year = {2009}, doi = {10.1097/nen.0b013e3181a9d503}, pmid = {19535999}, url = {https://doi.org/10.1097/nen.0b013e3181a9d503} } @article{nori2019-31879701, author = {Nori, V. S. and Hane, C. A. and Crown, W. H. and Au, R. and Burke, W. J. and Sanghavi, D. M. and Bleicher, P.}, title = {{Machine learning models to predict onset of dementia: A label learning approach}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2019}, doi = {10.1016/j.trci.2019.10.006}, pmid = {31879701}, url = {https://doi.org/10.1016/j.trci.2019.10.006} } @article{butler2020-32640168, author = {Butler, L. K. and Kiran, S. and Tager-Flusberg, H.}, title = {{Functional Near-Infrared Spectroscopy in the Study of Speech and Language Impairment Across the Life Span: A Systematic Review}}, journal = {American journal of speech-language pathology}, year = {2020}, doi = {10.1044/2020_ajslp-19-00050}, pmid = {32640168}, url = {https://doi.org/10.1044/2020_ajslp-19-00050} } @article{myers1996-8618665, author = {Myers, R. H. and Schaefer, E. J. and Wilson, P. W. and D'Agostino, R. and Ordovas, J. M. and Espino, A. and Au, R. and White, R. F. and others}, title = {{Apolipoprotein E epsilon4 association with dementia in a population-based study: The Framingham study}}, journal = {Neurology}, year = {1996}, doi = {10.1212/wnl.46.3.673}, pmid = {8618665}, url = {https://doi.org/10.1212/wnl.46.3.673} } @article{mckee2010-20720505, author = {McKee, A. C. and Gavett, B. E. and Stern, R. A. and Nowinski, C. J. and Cantu, R. C. and Kowall, N. W. and Perl, D. P. and Hedley-Whyte, E. T. and others}, title = {{TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy}}, journal = {Journal of neuropathology and experimental neurology}, year = {2010}, doi = {10.1097/nen.0b013e3181ee7d85}, pmid = {20720505}, url = {https://doi.org/10.1097/nen.0b013e3181ee7d85} } @article{you2022-35029059, author = {You, Y. and Muraoka, S. and Jedrychowski, M. P. and Hu, J. and McQuade, A. K. and Young-Pearse, T. and Aslebagh, R. and Shaffer, S. A. and others}, title = {{Human neural cell type-specific extracellular vesicle proteome defines disease-related molecules associated with activated astrocytes in Alzheimer's disease brain}}, journal = {Journal of extracellular vesicles}, year = {2022}, doi = {10.1002/jev2.12183}, pmid = {35029059}, url = {https://doi.org/10.1002/jev2.12183} } @article{jak2016-27029348, author = {Jak, A. J. and Preis, SR. and Beiser, A. S. and Seshadri, S. and Wolf, P. A. and Bondi, M. W. and Au, R.}, title = {{Neuropsychological Criteria for Mild Cognitive Impairment and Dementia Risk in the Framingham Heart Study}}, journal = {Journal of the International Neuropsychological Society : JINS}, year = {2016}, doi = {10.1017/s1355617716000199}, pmid = {27029348}, url = {https://doi.org/10.1017/s1355617716000199} } @article{ridge2016-27036079, author = {Ridge, P. G. and Hoyt, K. B. and Boehme, K. and Mukherjee, S. and Crane, P. K. and Haines, J. L. and Mayeux, R. and Farrer, L. A. and others}, title = {{Assessment of the genetic variance of late-onset Alzheimer's disease}}, journal = {Neurobiology of aging}, year = {2016}, doi = {10.1016/j.neurobiolaging.2016.02.024}, pmid = {27036079}, url = {https://doi.org/10.1016/j.neurobiolaging.2016.02.024} } @article{panitch2021-34480088, author = {Panitch, R. and Hu, J. and Chung, J. and Zhu, C. and Meng, G. and Xia, W. and Bennett, D. A. and Lunetta, K. L. and others}, title = {{Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE ε2 protective effect in Alzheimer disease}}, journal = {Molecular psychiatry}, year = {2021}, doi = {10.1038/s41380-021-01266-z}, pmid = {34480088}, url = {https://doi.org/10.1038/s41380-021-01266-z} } @article{mcgrath2019-30830941, author = {McGrath, E. R. and Himali, J. J. and Levy, D. and Conner, S. C. and Pase, M. P. and Abraham, C. R. and Courchesne, P. and Satizabal, C. L. and others}, title = {{Circulating fibroblast growth factor 23 levels and incident dementia: The Framingham heart study}}, journal = {PloS one}, year = {2019}, doi = {10.1371/journal.pone.0213321}, pmid = {30830941}, url = {https://doi.org/10.1371/journal.pone.0213321} } @article{li2023-37260021, author = {Li, D. and Farrell, J. J. and Mez, J. and Martin, E. R. and Bush, W. S. and Ruiz, A. and Boada, M. and de Rojas, I. and Mayeux, R. and Haines, J. L. and Vance, M. A. P. and Wang, L. S. and others}, title = {{Novel loci for Alzheimer's disease identified by a genome-wide association study in Ashkenazi Jews}}, journal = {Alzheimer's \& Dementia}, year = {2023}, doi = {10.1002/alz.13117}, pmid = {37260021}, url = {https://doi.org/10.1002/alz.13117} } @article{whitson2018-30248173, author = {Whitson, H. E. and Cronin-Golomb, A. and Cruickshanks, K. J. and Gilmore, G. C. and Owsley, C. and Peelle, J. E. and Recanzone, G. and Sharma, A. and others}, title = {{American Geriatrics Society and National Institute on Aging Bench-to-Bedside Conference: Sensory Impairment and Cognitive Decline in Older Adults}}, journal = {Journal of the American Geriatrics Society}, year = {2018}, doi = {10.1111/jgs.15506}, pmid = {30248173}, url = {https://doi.org/10.1111/jgs.15506} } @article{dubois2004-15039037, author = {Dubois, B. and Albert, M. L.}, title = {{Amnestic MCI or prodromal Alzheimer's disease?}}, journal = {The Lancet. Neurology}, year = {2004}, doi = {10.1016/s1474-4422(04)00710-0}, pmid = {15039037}, url = {https://doi.org/10.1016/s1474-4422(04)00710-0} } @article{jefferson2010-20679552, author = {Jefferson, A. L. and Himali, J. J. and Beiser, A. S. and Au, R. and Massaro, J. M. and Seshadri, S. and Gona, P. and Salton, C. J. and others}, title = {{Cardiac index is associated with brain aging: the Framingham Heart Study}}, journal = {Circulation}, year = {2010}, doi = {10.1161/circulationaha.109.905091}, pmid = {20679552}, url = {https://doi.org/10.1161/circulationaha.109.905091} } @article{elias2005-16223549, author = {Elias, M. F. and Elias, P. K. and Sullivan, L. M. and Wolf, P. A. and D'Agostino, R. B.}, title = {{Obesity, diabetes and cognitive deficit: The Framingham Heart Study}}, journal = {Neurobiology of aging}, year = {2005}, doi = {10.1016/j.neurobiolaging.2005.08.019}, pmid = {16223549}, url = {https://doi.org/10.1016/j.neurobiolaging.2005.08.019} } @article{miner2026-42440317, author = {Miner, A. E. and Zetterberg, H. and Blennow, K. and Groh, JR. and Singh, A. and Dieckhoff, K. and Tripodis, Y. and Adler, C. H. and others}, title = {{Plasma Phosphorylated Tau 217 in Participants at Risk for Chronic Traumatic Encephalopathy}}, journal = {JAMA network open}, year = {2026}, doi = {10.1001/jamanetworkopen.2026.22966}, pmid = {42440317}, url = {https://doi.org/10.1001/jamanetworkopen.2026.22966} } @article{chapman2016-26899835, author = {Chapman, K. R. and Bing-Canar, H. and Alosco, M. L. and Steinberg, E. G. and Martin, B. and Chaisson, C. and Kowall, N. and Tripodis, Y. and others}, title = {{Mini Mental State Examination and Logical Memory scores for entry into Alzheimer's disease trials}}, journal = {Alzheimer's research \& therapy}, year = {2016}, doi = {10.1186/s13195-016-0176-z}, pmid = {26899835}, url = {https://doi.org/10.1186/s13195-016-0176-z} } @article{vasan2022-35168368, author = {Vasan, R. S. and Pan, S. and Xanthakis, V. and Beiser, A. and Larson, M. G. and Seshadri, S. and Mitchell, G. F.}, title = {{Arterial Stiffness and Long-Term Risk of Health Outcomes: The Framingham Heart Study}}, journal = {Hypertension (Dallas, Tex. : 1979)}, year = {2022}, doi = {10.1161/hypertensionaha.121.18776}, pmid = {35168368}, url = {https://doi.org/10.1161/hypertensionaha.121.18776} } @article{choi2020-33313380, author = {Choi, S. E. and Mukherjee, S. and Gibbons, L. E. and Sanders, R. E. and Jones, R. N. and Tommet, D. and Mez, J. and Trittschuh, E. H. and others}, title = {{Development and validation of language and visuospatial composite scores in ADNI}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2020}, doi = {10.1002/trc2.12072}, pmid = {33313380}, url = {https://doi.org/10.1002/trc2.12072} } @article{romero2017-28347929, author = {Romero, JR. and Beiser, A. and Himali, J. J. and Shoamanesh, A. and DeCarli, C. and Seshadri, S.}, title = {{Cerebral microbleeds and risk of incident dementia: the Framingham Heart Study}}, journal = {Neurobiology of aging}, year = {2017}, doi = {10.1016/j.neurobiolaging.2017.02.018}, pmid = {28347929}, url = {https://doi.org/10.1016/j.neurobiolaging.2017.02.018} } @article{kumar2026-41616780, author = {Kumar, Mukesh and Schlaffner, Christoph N. and Tang, Shaojun and Beuvink, Maaike A. and Viodé, Arthur and Mair, Waltraud and Jha, Meenakshi and Uncu, Ceren and others}, title = {{Molecular features of human pathological tau distinguish tauopathy-associated dementias}}, journal = {Cell}, year = {2026}, doi = {10.1016/j.cell.2025.12.036}, pmid = {41616780}, url = {https://doi.org/10.1016/j.cell.2025.12.036} } @article{bachman1993-8450993, author = {Bachman, David and Wolf, Philip A. and Linn, Richard T. and Knoefel, Janice E. and Cobb, J. L. and Belanger, Albert J. and White, L. R. B. and D’Agostino, Ralph B.}, title = {{Incidence of dementia and probable Alzheimer's disease in a general population: the Framingham Study}}, journal = {Neurology}, year = {1993}, doi = {10.1212/wnl.43.3_part_1.515}, pmid = {8450993}, url = {https://doi.org/10.1212/wnl.43.3_part_1.515} } @article{mckee2014-24366527, author = {McKee, A. C. and Daneshvar, D. H. and Alvarez, V. E. and Stein, T. D.}, title = {{The neuropathology of sport}}, journal = {Acta neuropathologica}, year = {2014}, doi = {10.1007/s00401-013-1230-6}, pmid = {24366527}, url = {https://doi.org/10.1007/s00401-013-1230-6} } @article{poly2011-22071706, author = {Poly, C. and Massaro, J. M. and Seshadri, S. and Wolf, P. A. and Cho, E. and Krall, E. and Jacques, P. F. and Au, R.}, title = {{The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham Offspring Cohort}}, journal = {The American journal of clinical nutrition}, year = {2011}, doi = {10.3945/ajcn.110.008938}, pmid = {22071706}, url = {https://doi.org/10.3945/ajcn.110.008938} } @article{desikan2008-18672473, author = {Desikan, R. S. and Fischl, B. and Cabral, H. J. and Kemper, T. L. and Guttmann, C. R. and Blacker, D. and Hyman, B. T. and Albert, M. S. and others}, title = {{MRI measures of temporoparietal regions show differential rates of atrophy during prodromal AD}}, journal = {Neurology}, year = {2008}, doi = {10.1212/01.wnl.0000320055.57329.34}, pmid = {18672473}, url = {https://doi.org/10.1212/01.wnl.0000320055.57329.34} } @article{jeerakathil2004-15218158, author = {Jeerakathil, T. and Wolf, P. A. and Beiser, A. and Massaro, J. and Seshadri, S. and D'Agostino, R. B. and DeCarli, C.}, title = {{Stroke risk profile predicts white matter hyperintensity volume: the Framingham Study}}, journal = {Stroke}, year = {2004}, doi = {10.1161/01.str.0000135226.53499.85}, pmid = {15218158}, url = {https://doi.org/10.1161/01.str.0000135226.53499.85} } @article{ferrante1997-9349552, author = {Ferrante, R. J. and Browne, S. E. and Shinobu, L. A. and Bowling, A. C. and Baik, M. J. and MacGarvey, U. and Kowall, N. W. and Brown, R. H. and others}, title = {{Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis}}, journal = {Journal of neurochemistry}, year = {1997}, doi = {10.1046/j.1471-4159.1997.69052064.x}, pmid = {9349552}, url = {https://doi.org/10.1046/j.1471-4159.1997.69052064.x} } @article{jasodanand2025-40983947, author = {Jasodanand, Varuna H. and Bellitti, Matteo and Kolachalama, Vijaya B.}, title = {{An AI‐first framework for multimodal data in Alzheimer's disease and related dementias}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70719}, pmid = {40983947}, url = {https://doi.org/10.1002/alz.70719} } @article{lemere1996-9173910, author = {Lemere, Cynthia Ann and Blusztajn, Jan Krzysztof and Yamaguchi, Hiroki and Wisniewski, Thomas and Saido, Takaomi C. and Selkoe, Dennis J.}, title = {{Sequence of Deposition of Heterogeneous Amyloid β-Peptides and APO E in Down Syndrome: Implications for Initial Events in Amyloid Plaque Formation}}, journal = {Neurobiology of Disease}, year = {1996}, doi = {10.1006/nbdi.1996.0003}, pmid = {9173910}, url = {https://doi.org/10.1006/nbdi.1996.0003} } @article{jun2010-20697030, author = {Jun, G. and Naj, A. C. and Beecham, G. W. and Wang, L. S. and Buros, J. and Gallins, P. J. and Buxbaum, J. D. and Ertekin-Taner, N. and others}, title = {{Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes}}, journal = {Archives of neurology}, year = {2010}, doi = {10.1001/archneurol.2010.201}, pmid = {20697030}, url = {https://doi.org/10.1001/archneurol.2010.201} } @article{seshadri2007-18031707, author = {Seshadri, S. and Wolf, P. A.}, title = {{Lifetime risk of stroke and dementia: current concepts, and estimates from the Framingham Study}}, journal = {The Lancet. Neurology}, year = {2007}, doi = {10.1016/s1474-4422(07)70291-0}, pmid = {18031707}, url = {https://doi.org/10.1016/s1474-4422(07)70291-0} } @article{logue2019-29487403, author = {Logue, M. W. and Panizzon, M. S. and Elman, J. A. and Gillespie, N. A. and Hatton, S. N. and Gustavson, D. E. and Andreassen, O. A. and Dale, A. M. and others}, title = {{Use of an Alzheimer's disease polygenic risk score to identify mild cognitive impairment in adults in their 50s}}, journal = {Molecular psychiatry}, year = {2019}, doi = {10.1038/s41380-018-0030-8}, pmid = {29487403}, url = {https://doi.org/10.1038/s41380-018-0030-8} } @article{indorewalla2021-33612540, author = {Indorewalla, K. K. and O'Connor, M. K. and Budson, A. E. and Guess DiTerlizzi, C. and Jackson, J.}, title = {{Modifiable Barriers for Recruitment and Retention of Older Adults Participants from Underrepresented Minorities in Alzheimer's Disease Research}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2021}, doi = {10.3233/jad-201081}, pmid = {33612540}, url = {https://doi.org/10.3233/jad-201081} } @article{beaufort2026-42691466, author = {Beaufort, Q. and Charbonnier, C. and Ruellan, P. and Ozkul-Wermester, O. and Amar, V. and Turpin, D. and Quillard-Muraine, M. and Gerardin, E. and others}, title = {{Evaluation of Disease Severity Using CSF Biomarkers in Patients With Probable Cerebral Amyloid Angiopathy}}, journal = {Neurology}, year = {2026}, doi = {10.1212/wnl.0000000000218458}, pmid = {42691466}, url = {https://doi.org/10.1212/wnl.0000000000218458} } @article{hammond2025-41434365, author = {Hammond, Angel and Navaratna, Ruvini and Moody, Jason F. and DeWitt, Amanda and Alosco, Michael Louis and Atri, Alireza and Bakulski, Kelly M. and Beach, Thomas G. and others}, title = {{Association of Neighborhood‐Level Disadvantage with Antemortem MRI Brain Volumes in a Multi‐site Brain Bank Donor Cohort}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz70861_108929}, pmid = {41434365}, url = {https://doi.org/10.1002/alz70861_108929} } @article{mancini2025-40118834, author = {Mancini, Martina and Afshari, Mitra and Almeida, Quincy J. and Huffmaster, Sommer L. Amundsen and Balfany, Katherine and Camicioli, Richard M. and Christiansen, Cory L. and Dale, Marian L. and others}, title = {{Digital gait biomarkers in Parkinson’s disease: susceptibility/risk, progression, response to exercise, and prognosis}}, journal = {npj Parkinson s Disease}, year = {2025}, doi = {10.1038/s41531-025-00897-1}, pmid = {40118834}, url = {https://doi.org/10.1038/s41531-025-00897-1} } @article{wang2025-40537069, author = {Wang, Shuyue and Zhang, Fan and Zeng, Qingze and Hong, Hui and Zhang, Yao and Xie, Linyun and Miao, Lin and Jiaerken, Yeerfan and others}, title = {{Association of Superficial White Matter Microstructure With Cortical Pathology Deposition Across Early Stages of the AD Continuum}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000213666}, pmid = {40537069}, url = {https://doi.org/10.1212/wnl.0000000000213666} } @article{urbano2025-40609908, author = {Urbano, Teresa and Michalke, Bernhard and Chiari, Annalisa and Malagoli, Carlotta and Bedin, Roberta and Tondelli, Manuela and Vinceti, Marco and Filippini, Tommaso}, title = {{Iron species in cerebrospinal fluid and dementia risk in subjects with mild cognitive impairment: A cohort study}}, journal = {NeuroToxicology}, year = {2025}, doi = {10.1016/j.neuro.2025.06.006}, pmid = {40609908}, url = {https://doi.org/10.1016/j.neuro.2025.06.006} } @article{larusse2005-15654228, author = {LaRusse, S. and Roberts, J. S. and Marteau, T. M. and Katzen, H. and Linnenbringer, E. L. and Barber, M. and Whitehouse, P. and Quaid, K. and others}, title = {{Genetic susceptibility testing versus family history-based risk assessment: Impact on perceived risk of Alzheimer disease}}, journal = {Genetics in medicine : official journal of the American College of Medical Genetics}, year = {2005}, doi = {10.1097/01.gim.0000151157.13716.6c}, pmid = {15654228}, url = {https://doi.org/10.1097/01.gim.0000151157.13716.6c} } @article{montenigro2014-25580160, author = {Montenigro, P. H. and Baugh, C. M. and Daneshvar, D. H. and Mez, J. and Budson, A. E. and Au, R. and Katz, D. I. and Cantu, R. C. and others}, title = {{Clinical subtypes of chronic traumatic encephalopathy: literature review and proposed research diagnostic criteria for traumatic encephalopathy syndrome}}, journal = {Alzheimer's research \& therapy}, year = {2014}, doi = {10.1186/s13195-014-0068-z}, pmid = {25580160}, url = {https://doi.org/10.1186/s13195-014-0068-z} } @article{gavett2011-21074091, author = {Gavett, B. E. and Stern, R. A. and McKee, A. C.}, title = {{Chronic traumatic encephalopathy: a potential late effect of sport-related concussive and subconcussive head trauma}}, journal = {Clinics in sports medicine}, year = {2011}, doi = {10.1016/j.csm.2010.09.007}, pmid = {21074091}, url = {https://doi.org/10.1016/j.csm.2010.09.007} } @article{kenney2018-29155947, author = {Kenney, K. and Iacono, D. and Edlow, B. L. and Katz, D. I. and Diaz-Arrastia, R. and Dams-O'Connor, K. and Daneshvar, D. H. and Stevens, A. and others}, title = {{Dementia After Moderate-Severe Traumatic Brain Injury: Coexistence of Multiple Proteinopathies}}, journal = {Journal of neuropathology and experimental neurology}, year = {2018}, doi = {10.1093/jnen/nlx101}, pmid = {29155947}, url = {https://doi.org/10.1093/jnen/nlx101} } @article{mckee2015-25702209, author = {Mckee, A. C. and Daneshvar, D. H.}, title = {{The neuropathology of traumatic brain injury}}, journal = {Handbook of clinical neurology}, year = {2015}, doi = {10.1016/b978-0-444-52892-6.00004-0}, pmid = {25702209}, url = {https://doi.org/10.1016/b978-0-444-52892-6.00004-0} } @article{dubal2015-25673831, author = {Dubal, D. B. and Zhu, L. and Sanchez, P. E. and Worden, K. and Broestl, L. and Johnson, E. and Ho, K. and Yu, G. Q. and others}, title = {{Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2015}, doi = {10.1523/jneurosci.5791-12.2015}, pmid = {25673831}, url = {https://doi.org/10.1523/jneurosci.5791-12.2015} } @article{au2006-16476813, author = {Au, R. and Massaro, J. M. and Wolf, P. A. and Young, M. E. and Beiser, A. and Seshadri, S. and D'Agostino, R. B. and DeCarli, C.}, title = {{Association of white matter hyperintensity volume with decreased cognitive functioning: the Framingham Heart Study}}, journal = {Archives of neurology}, year = {2006}, doi = {10.1001/archneur.63.2.246}, pmid = {16476813}, url = {https://doi.org/10.1001/archneur.63.2.246} } @article{lahoz2001-11257253, author = {Lahoz, C. and Schaefer, E. J. and Cupples, L. A. and Wilson, P. W. and Levy, D. and Osgood, D. and Parpos, S. and Pedro-Botet, J. and others}, title = {{Apolipoprotein E genotype and cardiovascular disease in the Framingham Heart Study}}, journal = {Atherosclerosis}, year = {2001}, doi = {10.1016/s0021-9150(00)00570-0}, pmid = {11257253}, url = {https://doi.org/10.1016/s0021-9150(00)00570-0} } @article{au2012-22471865, author = {Au, R. and Seshadri, S. and Knox, K. and Beiser, A. and Himali, J. J. and Cabral, H. J. and Auerbach, S. and Green, R. C. and others}, title = {{The Framingham Brain Donation Program: neuropathology along the cognitive continuum}}, journal = {Current Alzheimer research}, year = {2012}, doi = {10.2174/156720512801322609}, pmid = {22471865}, url = {https://doi.org/10.2174/156720512801322609} } @article{petrea2020-32755403, author = {Petrea, R. E. and O'Donnell, A. and Beiser, A. S. and Habes, M. and Aparicio, H. and DeCarli, C. and Seshadri, S. and Romero, JR.}, title = {{Mid to Late Life Hypertension Trends and Cerebral Small Vessel Disease in the Framingham Heart Study}}, journal = {Hypertension (Dallas, Tex. : 1979)}, year = {2020}, doi = {10.1161/hypertensionaha.120.15073}, pmid = {32755403}, url = {https://doi.org/10.1161/hypertensionaha.120.15073} } @article{baugh2012-22552850, author = {Baugh, C. M. and Stamm, J. M. and Riley, D. O. and Gavett, B. E. and Shenton, M. E. and Lin, A. and Nowinski, C. J. and Cantu, R. C. and others}, title = {{Chronic traumatic encephalopathy: neurodegeneration following repetitive concussive and subconcussive brain trauma}}, journal = {Brain imaging and behavior}, year = {2012}, doi = {10.1007/s11682-012-9164-5}, pmid = {22552850}, url = {https://doi.org/10.1007/s11682-012-9164-5} } @article{lee2003-12655043, author = {Lee, J. and Ryu, H. and Ferrante, R. J. and Morris, S. M. and Ratan, R. R.}, title = {{Translational control of inducible nitric oxide synthase expression by arginine can explain the arginine paradox}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2003}, doi = {10.1073/pnas.0735876100}, pmid = {12655043}, url = {https://doi.org/10.1073/pnas.0735876100} } @article{besser2023-37174185, author = {Besser, Lilah M. and Jimenez, Marcia Pescador and Reimer, Cameron J. and Meyer, Oanh L. and Mitsova, Diana and George, Kristen M. and Adkins‐Jackson, Paris B. and Galvin, James E.}, title = {{Diversity of Studies on Neighborhood Greenspace and Brain Health by Racialized/Ethnic Group and Geographic Region: A Rapid Review}}, journal = {International Journal of Environmental Research and Public Health}, year = {2023}, doi = {10.3390/ijerph20095666}, pmid = {37174185}, url = {https://doi.org/10.3390/ijerph20095666} } @article{gonzales2023-37813589, author = {Gonzales, M. M. and Vela, G. and Philip, V. and Trevino, H. and LaRoche, A. and Wang, C. P. and Parent, D. M. and Kautz, T. and others}, title = {{Demographic and Clinical Characteristics Associated With Serum GFAP Levels in an Ethnically Diverse Cohort}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000207706}, pmid = {37813589}, url = {https://doi.org/10.1212/wnl.0000000000207706} } @article{mckee2015-25904048, author = {McKee, A. C. and Stein, T. D. and Kiernan, P. T. and Alvarez, V. E.}, title = {{The neuropathology of chronic traumatic encephalopathy}}, journal = {Brain pathology (Zurich, Switzerland)}, year = {2015}, doi = {10.1111/bpa.12248}, pmid = {25904048}, url = {https://doi.org/10.1111/bpa.12248} } @article{stern2011-22035690, author = {Stern, R. A. and Riley, D. O. and Daneshvar, D. H. and Nowinski, C. J. and Cantu, R. C. and McKee, A. C.}, title = {{Long-term consequences of repetitive brain trauma: chronic traumatic encephalopathy}}, journal = {PM \& R : the journal of injury, function, and rehabilitation}, year = {2011}, doi = {10.1016/j.pmrj.2011.08.008}, pmid = {22035690}, url = {https://doi.org/10.1016/j.pmrj.2011.08.008} } @article{takahashi2017-28070672, author = {Takahashi, H. and Klein, Z. A. and Bhagat, S. M. and Kaufman, A. C. and Kostylev, M. A. and Ikezu, T. and Strittmatter, S. M. and {Alzheimer’s Disease Neuroimaging Initiative}}, title = {{Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network}}, journal = {Acta neuropathologica}, year = {2017}, doi = {10.1007/s00401-017-1668-z}, pmid = {28070672}, url = {https://doi.org/10.1007/s00401-017-1668-z} } @article{saltmarche2017-28186867, author = {Saltmarche, A. E. and Naeser, M. A. and Ho, K. F. and Hamblin, M. R. and Lim, L.}, title = {{Significant Improvement in Cognition in Mild to Moderately Severe Dementia Cases Treated with Transcranial Plus Intranasal Photobiomodulation: Case Series Report}}, journal = {Photomedicine and laser surgery}, year = {2017}, doi = {10.1089/pho.2016.4227}, pmid = {28186867}, url = {https://doi.org/10.1089/pho.2016.4227} } @article{weinstein2013-23920020, author = {Weinstein, G. and Beiser, A. S. and Decarli, C. and Au, R. and Wolf, P. A. and Seshadri, S.}, title = {{Brain imaging and cognitive predictors of stroke and Alzheimer disease in the Framingham Heart Study}}, journal = {Stroke}, year = {2013}, doi = {10.1161/strokeaha.113.000947}, pmid = {23920020}, url = {https://doi.org/10.1161/strokeaha.113.000947} } @article{ahangaran2025-40084735, author = {Ahangaran, Meysam and Dawalatabad, Nauman and Karjadi, Cody and Glass, James and Au, Rhoda and Kolachalama, Vijaya B.}, title = {{Obfuscation via pitch‐shifting for balancing privacy and diagnostic utility in voice‐based cognitive assessment}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70032}, pmid = {40084735}, url = {https://doi.org/10.1002/alz.70032} } @article{mungas2025-40747592, author = {Mungas, Dan and Gavett, Brandon E. and Rojas‐Saunero, Liliana Paloma and Zhou, Yixuan and Hayes‐Larson, Eleanor and Shaw, Crystal L. and Farias, Sarah Tomaszewski and Widaman, Keith F. and others}, title = {{Machine learning diagnosis of cognitive impairment and dementia in harmonized older adult cohorts}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70508}, pmid = {40747592}, url = {https://doi.org/10.1002/alz.70508} } @article{young2025-40257009, author = {Young, Vanessa M. and Bernal, Rebecca and Baril, Andrée‐Ann and Zeynoun, Joy and Wiedner, Crystal and Gaona, Carlos A. and Beiser, Alexa and Teixeira, Antônio Lúcio and others}, title = {{Long sleep duration, cognitive performance, and the moderating role of depression: A cross‐sectional analysis in the Framingham Heart Study}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70160}, pmid = {40257009}, url = {https://doi.org/10.1002/alz.70160} } @article{kolo2025-41434410, author = {Kolo, Francis Babaman and Lu, Sophia Francesca DP and Beiser, Alexa S. and Francis, Lily and van Lent, Debora Melo and Goss, Monica and Saptaparni, Ghosh and Ting, Shu Jie and others}, title = {{Association of hearing loss to brain structure and cognition in the Framingham Heart Study}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz70860_101741}, pmid = {41434410}, url = {https://doi.org/10.1002/alz70860_101741} } @article{ekenze2025-40867146, author = {Ekenze, Oluchi Stella and Pinheiro, Adlin and Beiser, Alexa S. and Lioutas, Vasileios‐Arsenios and Aparicio, Hugo Javier and Benjamin, Emelia J. and Vasan, Ramachandran Srini and DeCarli, Charles S and others}, title = {{Prevalent Cardiovascular Disease and Atrial Fibrillation in Relation to Cerebral Small Vessel Disease Burden}}, journal = {Brain Sciences}, year = {2025}, doi = {10.3390/brainsci15080813}, pmid = {40867146}, url = {https://doi.org/10.3390/brainsci15080813} } @article{chua2022-f2eb762d, author = {Chua, Kao-Ping and Lee, Joyce M. and Tucker, Joshua E. and Seo, Dominique and Conti, Rena M.}, title = {{Benefits and Cost of a \$35 Insulin Cost-Sharing Cap for Medicare Patients}}, year = {2022}, doi = {10.1101/2022.01.06.22268864}, url = {https://doi.org/10.1101/2022.01.06.22268864} } @article{decarli2005-15653178, author = {DeCarli, Charles S and Massaro, Joseph M. and Harvey, Danielle Jenine and Hald, John K and Tullberg, Mats and Au, Rhoda and Beiser, Alexa S. and D’Agostino, Ralph B. and Wolf, Philip A.}, title = {{Measures of brain morphology and infarction in the framingham heart study: establishing what is normal}}, journal = {Neurobiology of Aging}, year = {2005}, doi = {10.1016/j.neurobiolaging.2004.05.004}, pmid = {15653178}, url = {https://doi.org/10.1016/j.neurobiolaging.2004.05.004} } @article{logue2011-22159054, author = {Logue, M. W. and Schu, M. and Vardarajan, B. N. and Buros, J. and Green, R. C. and Go, R. C. and Griffith, P. and Obisesan, T. O. and others}, title = {{A comprehensive genetic association study of Alzheimer disease in African Americans}}, journal = {Archives of neurology}, year = {2011}, doi = {10.1001/archneurol.2011.646}, pmid = {22159054}, url = {https://doi.org/10.1001/archneurol.2011.646} } @article{yip2005-16043796, author = {Yip, A. G. and McKee, A. C. and Green, R. C. and Wells, J. and Young, H. and Cupples, L. A. and Farrer, L. A.}, title = {{APOE, vascular pathology, and the AD brain}}, journal = {Neurology}, year = {2005}, doi = {10.1212/01.wnl.0000168863.49053.4d}, pmid = {16043796}, url = {https://doi.org/10.1212/01.wnl.0000168863.49053.4d} } @article{mandelblatt2014-24841981, author = {Mandelblatt, J. S. and Stern, R. A. and Luta, G. and McGuckin, M. and Clapp, J. D. and Hurria, A. and Jacobsen, P. B. and others}, title = {{Cognitive impairment in older patients with breast cancer before systemic therapy: is there an interaction between cancer and comorbidity?}}, journal = {Journal of clinical oncology : official journal of the American Society of Clinical Oncology}, year = {2014}, doi = {10.1200/jco.2013.54.2050}, pmid = {24841981}, url = {https://doi.org/10.1200/jco.2013.54.2050} } @article{frost2013-23747948, author = {Frost, J. L. and Le, K. X. and Cynis, H. and Ekpo, E. and Kleinschmidt, M. and Palmour, R. M. and Ervin, F. R. and Snigdha, S. and others}, title = {{Pyroglutamate-3 amyloid-β deposition in the brains of humans, non-human primates, canines, and Alzheimer disease-like transgenic mouse models}}, journal = {The American journal of pathology}, year = {2013}, doi = {10.1016/j.ajpath.2013.05.005}, pmid = {23747948}, url = {https://doi.org/10.1016/j.ajpath.2013.05.005} } @article{lai2021-34300282, author = {Lai, F. and Mercaldo, N. and Wang, C. M. and Hersch, G. G. and Rosas, H. D.}, title = {{Association between Inflammatory Conditions and Alzheimer's Disease Age of Onset in Down Syndrome}}, journal = {Journal of clinical medicine}, year = {2021}, doi = {10.3390/jcm10143116}, pmid = {34300282}, url = {https://doi.org/10.3390/jcm10143116} } @article{vardarajan2012-22673115, author = {Vardarajan, B. N. and Bruesegem, S. Y. and Harbour, M. E. and Inzelberg, R. and Friedland, R. and St George-Hyslop, P. and Seaman, M. N. and Farrer, L. A.}, title = {{Identification of Alzheimer disease-associated variants in genes that regulate retromer function}}, journal = {Neurobiology of aging}, year = {2012}, doi = {10.1016/j.neurobiolaging.2012.04.020}, pmid = {22673115}, url = {https://doi.org/10.1016/j.neurobiolaging.2012.04.020} } @article{chouraki2014-25311924, author = {Chouraki, V. and Seshadri, S.}, title = {{Genetics of Alzheimer's disease}}, journal = {Advances in genetics}, year = {2014}, doi = {10.1016/b978-0-12-800149-3.00005-6}, pmid = {25311924}, url = {https://doi.org/10.1016/b978-0-12-800149-3.00005-6} } @article{panitch2020-51e773db, author = {Panitch, R. and Hu, J. and Chung, J. and Zhu, C. and Meng, G. and Xia, W. and Bennett, D. A. and Lunetta, K. L. and others}, title = {{Integrative Brain Transcriptome Analysis Links Complement Component 4 andHSPA2to theAPOEε2 Protective Effect in Alzheimer Disease}}, journal = {Molecular psychiatry}, year = {2020}, doi = {10.1101/2020.11.23.20235762}, url = {https://doi.org/10.1101/2020.11.23.20235762} } @article{knopman2015-26453643, author = {Knopman, D. S. and Beiser, A. and Machulda, M. M. and Fields, J. and Roberts, R. O. and Pankratz, V. S. and Aakre, J. and Cha, R. H. and others}, title = {{Spectrum of cognition short of dementia: Framingham Heart Study and Mayo Clinic Study of Aging}}, journal = {Neurology}, year = {2015}, doi = {10.1212/wnl.0000000000002100}, pmid = {26453643}, url = {https://doi.org/10.1212/wnl.0000000000002100} } @article{anekwe2025-40937901, author = {Anekwe, Chika Vera and Cano, Antonio Rico and Mulligan, Jennifer and Ang, Seng Bin and Johnson, Corinne N. and Panay, Nick and Schaedel, Zoe and Akam, Eftitan Y. and others}, title = {{The role of lifestyle medicine in menopausal health: a review of non-pharmacologic interventions}}, journal = {Climacteric}, year = {2025}, doi = {10.1080/13697137.2025.2548806}, pmid = {40937901}, url = {https://doi.org/10.1080/13697137.2025.2548806} } @article{meza2025-39868479, author = {Meza, Erika and Romero, Karla Renata Flores and Allen, Isabel Elaine and González, Héctor M. and Glymour, M. Maria and Torres, Jacqueline M.}, title = {{Offspring education and cognitive health: A comparison between Hispanic and White older adults in the United States}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.14523}, pmid = {39868479}, url = {https://doi.org/10.1002/alz.14523} } @article{lenoel2025-40858618, author = {Lenoël, Isadora and Ribon, Matthieu and Lorenc, Félicie and Diebold, Aurélien and Philibert, Clémentine Eva and Robaldo, David and Badsi, Manel and Perronnet, Julianne and others}, title = {{ALS/FTD-linked TBK1 deficiency in microglia induces an aged-like microglial signature and drives social recognition deficits in mice}}, journal = {Nature Communications}, year = {2025}, doi = {10.1038/s41467-025-63211-w}, pmid = {40858618}, url = {https://doi.org/10.1038/s41467-025-63211-w} } @article{pinheiro2025-41195792, author = {Pinheiro, Adlin and Aparicio, Hugo Javier and Lioutas, Vasileios‐Arsenios and Beiser, Alexa S. and Ekenze, Oluchi Stella and DeCarli, Charles S and Seshadri, Sudha S. and Demissie, Serkalem and others}, title = {{Higher Burden of Cerebral Small Vessel Disease Is Associated With Risk of Incident Stroke in Community‐Dwelling Individuals}}, journal = {Journal of the American Heart Association}, year = {2025}, doi = {10.1161/jaha.124.040263}, pmid = {41195792}, url = {https://doi.org/10.1161/jaha.124.040263} } @article{jun2012-22869155, author = {Jun, G. and Vardarajan, B. N. and Buros, J. and Yu, C. E. and Hawk, M. V. and Dombroski, B. A. and Crane, P. K. and Larson, E. B. and others}, title = {{Comprehensive search for Alzheimer disease susceptibility loci in the APOE region}}, journal = {Archives of neurology}, year = {2012}, doi = {10.1001/archneurol.2012.2052}, pmid = {22869155}, url = {https://doi.org/10.1001/archneurol.2012.2052} } @article{jun2012-22984439, author = {Jun, G. and Moncaster, J. A. and Koutras, C. and Seshadri, S. and Buros, J. and McKee, A. C. and Levesque, G. and Wolf, P. A. and others}, title = {{δ-Catenin is genetically and biologically associated with cortical cataract and future Alzheimer-related structural and functional brain changes}}, journal = {PloS one}, year = {2012}, doi = {10.1371/journal.pone.0043728}, pmid = {22984439}, url = {https://doi.org/10.1371/journal.pone.0043728} } @article{lai2021-34573243, author = {Lai, F. and Mercaldo, N. D. and Wang, C. M. and Hersch, M. S. and Hersch, G. G. and Rosas, H. D.}, title = {{Association between Hypothyroidism Onset and Alzheimer Disease Onset in Adults with Down Syndrome}}, journal = {Brain sciences}, year = {2021}, doi = {10.3390/brainsci11091223}, pmid = {34573243}, url = {https://doi.org/10.3390/brainsci11091223} } @article{chou2010-20878991, author = {Chou, K. L. and Amick, M. M. and Brandt, J. and Camicioli, R. and Frei, K. and Gitelman, D. and Goldman, J. and Growdon, J. and others}, title = {{A recommended scale for cognitive screening in clinical trials of Parkinson's disease}}, journal = {Movement disorders : official journal of the Movement Disorder Society}, year = {2010}, doi = {10.1002/mds.23362}, pmid = {20878991}, url = {https://doi.org/10.1002/mds.23362} } @article{walsh2026-42048404, author = {Walsh, Sebastian and Röhr, Susanne and Migeot, Joaquín and Bodryzlova, Yuliya and Ma’u, Etuini and Salemme, Simone and Marshall, Charles R. and Daly, Timothy P and others}, title = {{The principles of Population-Level Approaches to Dementia Risk Reduction (PLADRR)}}, journal = {PLoS Medicine}, year = {2026}, doi = {10.1371/journal.pmed.1005059}, pmid = {42048404}, url = {https://doi.org/10.1371/journal.pmed.1005059} } @article{ramoscejudo2025-41187307, author = {Ramos‐Cejudo, Jaime and Beiser, Alexa S. and Lu, Sophia Francesca DP and Tanner, Jeremy A. and Scott, Matthew R. and He, Tianshe and Ghosh, Saptaparni and Johnson, Keith A. and others}, title = {{Association of Platelet Aggregation With Markers of Alzheimer Disease Pathology in Middle-Aged Participants of the Framingham Heart Study}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000214314}, pmid = {41187307}, url = {https://doi.org/10.1212/wnl.0000000000214314} } @article{guo2025-40693440, author = {Guo, Muqi and Bassil, Darina T. and Farrell, Meagan T. and Wagner, Ryan Gregory and Tipping, Brent and Mahlalela, Nomsa Brightness and Kapaon, David and Tollman, Stephen and others}, title = {{Sensory impairment and dementia risk among older adults in rural South Africa}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70513}, pmid = {40693440}, url = {https://doi.org/10.1002/alz.70513} } @article{yang2026-41794745, author = {Yang, Jingmei and Ding, Huitong and Amini, Samad and Hao, Boran and Karjadi, Cody and Au, Rhoda and Paschalidis, Ioannis Ch.}, title = {{Resource-stratified machine learning framework for cognitive status classification and mild cognitive impairment to dementia progression prediction}}, journal = {Alzheimer s Research \& Therapy}, year = {2026}, doi = {10.1186/s13195-026-02006-7}, pmid = {41794745}, url = {https://doi.org/10.1186/s13195-026-02006-7} } @article{melgarejo2025-40138432, author = {Melgarejo, Jesús D. and Patil, Dhrumil and Charisis, Sokratis and Vatcheva, Kristina P. and Mejía-Arango, Silvia and Mena, Luis Javier and Satizábal, Claudia Liliana and Gaona, Ciro A. and others}, title = {{Baseline associations of office and ambulatory blood pressure monitoring with cognitive function and dementia prevalence}}, journal = {Journal of Alzheimer s Disease}, year = {2025}, doi = {10.1177/13872877251322400}, pmid = {40138432}, url = {https://doi.org/10.1177/13872877251322400} } @article{biard2025-40915983, author = {Biard, Marie and Detcheverry, Flavie E. and Betzner, William and Becker, Sara A. and Grewal, Karl Singh and Azab, Sandi and Bloniasz, Patrick Francis and Mazerolle, Erin L. and others}, title = {{Supporting decision making for individuals living with dementia and their care partners with knowledge translation: An umbrella review}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70636}, pmid = {40915983}, url = {https://doi.org/10.1002/alz.70636} } @article{shuhei2026-41747529, author = {Shuhei, Kobayashi and Atsushi, Nakagomi and Kazushige, Ide and Yu-Ru, Chen and Masamichi, Hanazato and Katsunori, Kondo and Koichiro, Shiba}, title = {{Neighborhood food store and subsequent health and well-being of older adults in Japan: an outcome-wide study}}, journal = {Archives of gerontology and geriatrics}, year = {2026}, doi = {10.1016/j.archger.2026.106186}, pmid = {41747529}, url = {https://doi.org/10.1016/j.archger.2026.106186} } @article{armstrong2021-33180114, author = {Armstrong, G. W. and Kim, L. A. and Vingopoulos, F. and Park, J. Y. and Garg, I. and Kasetty, M. and Silverman, R. F. and Zeng, R. and others}, title = {{Retinal Imaging Findings in Carriers With PSEN1-Associated Early-Onset Familial Alzheimer Disease Before Onset of Cognitive Symptoms}}, journal = {JAMA ophthalmology}, year = {2021}, doi = {10.1001/jamaophthalmol.2020.4909}, pmid = {33180114}, url = {https://doi.org/10.1001/jamaophthalmol.2020.4909} } @article{safransky2024-39496102, author = {Safransky, M. and Groh, JR. and Blennow, K. and Zetterberg, H. and Tripodis, Y. and Martin, B. and Weller, J. and Asken, B. M. and others}, title = {{Lumipulse-Measured Cerebrospinal Fluid Biomarkers for the Early Detection of Alzheimer Disease}}, journal = {Neurology}, year = {2024}, doi = {10.1212/wnl.0000000000209866}, pmid = {39496102}, url = {https://doi.org/10.1212/wnl.0000000000209866} } @article{bis2020-30108311, author = {Bis, J. C. and Jian, X. and Kunkle, B. W. and Chen, Y. and Hamilton-Nelson, K. L. and Bush, W. S. and Salerno, W. J. and Lancour, D. and others}, title = {{Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation}}, journal = {Molecular psychiatry}, year = {2020}, doi = {10.1038/s41380-018-0112-7}, pmid = {30108311}, url = {https://doi.org/10.1038/s41380-018-0112-7} } @article{marin2022-36094804, author = {Marin, A. and DeCaro, R. and Schiloski, K. and Elshaar, A. and Dwyer, B. and Vives-Rodriguez, A. and Palumbo, R. and Turk, K. and others}, title = {{Home-Based Electronic Cognitive Therapy in Patients With Alzheimer Disease: Feasibility Randomized Controlled Trial}}, journal = {JMIR formative research}, year = {2022}, doi = {10.2196/34450}, pmid = {36094804}, url = {https://doi.org/10.2196/34450} } @article{akhterkhan2020-36037052, author = {Akhter-Khan, S. C. and Au, R.}, title = {{Why Loneliness Interventions Are Unsuccessful: A Call for Precision Health}}, journal = {Advances in geriatric medicine and research}, year = {2020}, doi = {10.20900/agmr20200016}, pmid = {36037052}, url = {https://doi.org/10.20900/agmr20200016} } @article{rubenstein2025-41105592, author = {Rubenstein, E. and Tewolde, S. and Michals, A. and Fortea, J. and Jimenez, M. P. and Skotko, B. G. and Tripodis, Y. and Weuve, J. and others}, title = {{Novel predictors of Alzheimer's disease in Down syndrome identified using machine learning}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2025}, doi = {10.1177/13872877251385423}, pmid = {41105592}, url = {https://doi.org/10.1177/13872877251385423} } @article{rosenberg2016-27135718, author = {Rosenberg, R. N. and Lambracht-Washington, D. and Yu, G. and Xia, W.}, title = {{Genomics of Alzheimer Disease: A Review}}, journal = {JAMA neurology}, year = {2016}, doi = {10.1001/jamaneurol.2016.0301}, pmid = {27135718}, url = {https://doi.org/10.1001/jamaneurol.2016.0301} } @article{clayton2017-29311768, author = {Clayton, K. A. and Van Enoo, A. A. and Ikezu, T.}, title = {{Alzheimer's Disease: The Role of Microglia in Brain Homeostasis and Proteopathy}}, journal = {Frontiers in neuroscience}, year = {2017}, doi = {10.3389/fnins.2017.00680}, pmid = {29311768}, url = {https://doi.org/10.3389/fnins.2017.00680} } @article{wolf2007-17430232, author = {Wolf, P. A. and Beiser, A. and Elias, M. F. and Au, R. and Vasan, R. S. and Seshadri, S.}, title = {{Relation of obesity to cognitive function: importance of central obesity and synergistic influence of concomitant hypertension. The Framingham Heart Study}}, journal = {Current Alzheimer research}, year = {2007}, doi = {10.2174/156720507780362263}, pmid = {17430232}, url = {https://doi.org/10.2174/156720507780362263} } @article{baril2022-34310026, author = {Baril, A. A. and Beiser, A. S. and Sanchez, E. and Mysliwiec, V. and Redline, S. and Gottlieb, D. J. and O'Connor, G. T. and Gonzales, M. M. and others}, title = {{Insomnia symptom severity and cognitive performance: Moderating role of APOE genotype}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2022}, doi = {10.1002/alz.12405}, pmid = {34310026}, url = {https://doi.org/10.1002/alz.12405} } @article{kropp2026-42546232, author = {Kropp, Emerson and Varkanitsa, Maria and Stein, Thor D. and Turk, Katherine W. and Alosco, Michael Louis and Tripodis, Yorghos and Romero, Jose Rafael and Kiran, Swathi and others}, title = {{Diagnostic Accuracy of the Boston Criteria v2.0 in Memory Clinic Patients}}, journal = {Neurology}, year = {2026}, doi = {10.1212/wnl.0000000000218314}, pmid = {42546232}, url = {https://doi.org/10.1212/wnl.0000000000218314} } @article{yiallourou2026-42525904, author = {Yiallourou, Stephanie R and Wiedner, Crystal and Yang, Qiong and Baril, Andrée‐Ann and Misialek, Jeffrey R. and Kline, Christopher E. and Harrison, Stephanie and Bernal, Rebecca and others}, title = {{Association of Sleep Variables With Cognitive Performance and the Risk of Dementia in the Sleep and Dementia Consortium}}, journal = {Neurology}, year = {2026}, doi = {10.1212/wnl.0000000000218182}, pmid = {42525904}, url = {https://doi.org/10.1212/wnl.0000000000218182} } @article{chen2026-41760714, author = {Chen, Jiachen and Doyle, Margaret F. and Cao, Yumeng and Iyer, Sandhya and Ragab, Ahmed A. Y. and Murabito, Joanne M. and Lunetta, Kathryn L.}, title = {{Circulating immune cell phenotypes are associated with inflammatory biomarkers in dementia-free participants from the Framingham Heart Study Offspring cohort}}, journal = {Scientific Reports}, year = {2026}, doi = {10.1038/s41598-026-41423-4}, pmid = {41760714}, url = {https://doi.org/10.1038/s41598-026-41423-4} } @article{higgins2026-40903895, author = {Higgins, A. and Tewolde, S. and Page, S. D. and Rubenstein, E.}, title = {{The Occurrence of Obstructive Sleep Apnea and Its Association With Alzheimer Dementia in Medicaid-Enrolled Adults With Down Syndrome, 2011-2019}}, journal = {American journal of medical genetics. Part A}, year = {2026}, doi = {10.1002/ajmg.a.64241}, pmid = {40903895}, url = {https://doi.org/10.1002/ajmg.a.64241} } @article{elias2005-15673620, author = {Elias, P. K. and Elias, M. F. and D'Agostino, R. B. and Sullivan, L. M. and Wolf, P. A.}, title = {{Serum cholesterol and cognitive performance in the Framingham Heart Study}}, journal = {Psychosomatic medicine}, year = {2005}, doi = {10.1097/01.psy.0000151745.67285.c2}, pmid = {15673620}, url = {https://doi.org/10.1097/01.psy.0000151745.67285.c2} } @article{vahidy2023-8cbc6a22, author = {Vahidy, Farhaan and Hosseini, Akram A. and Girard, Timothy D. and Ibrahim, Tamer S. and Jacobs, Heidi I.L. and Román, Gustavo C. and Masdeu, Joseph C. and Li, Karl and others}, title = {{Disparities in Research Participation within a Multi‐Racial SARS‐CoV‐2 Cohort for Evaluation of Ultrahigh Field (7T) MRI and Clinical Precursors of Alzheimer’s Disease and Related Dementias}}, journal = {Alzheimer s \& Dementia}, year = {2023}, doi = {10.1002/alz.077318}, url = {https://doi.org/10.1002/alz.077318} } @article{li2025-39910859, author = {Li, Jinlei and Liu, Chunyu and Ang, Ting Fang Alvin and Au, Rhoda}, title = {{Associations of Mid‐ and Late‐Life Fasting Blood Glucose Levels With Dementia Risk Among Patients With Diabetes: Framingham Heart Study}}, journal = {European Journal of Neurology}, year = {2025}, doi = {10.1111/ene.70062}, pmid = {39910859}, url = {https://doi.org/10.1111/ene.70062} } @article{deandaduran2025-40267270, author = {De Anda‐Duran, Ileana and Hwang, Phillip H and Drabick, Deborah A. G. and Andersen, Stacy L. and Au, Rhoda and Libon, David J.}, title = {{Neuropsychological phenotypic characteristics in a cohort of community-based older adults: Data from the Framingham Heart Study}}, journal = {Journal of Alzheimer s Disease}, year = {2025}, doi = {10.1177/13872877251334608}, pmid = {40267270}, url = {https://doi.org/10.1177/13872877251334608} } @article{parankusham2026-7da4a6e3, author = {Parankusham, H. and Vanderlip, C. and Birkenbihl, C. and Krishna, E. and Ugboaja, C. and Budson, A. and Frank, B.}, title = {{A Two-Stage Plasma Biomarker Algorithm Reduces Amyloid PET Use and the p-Tau217 Gray Zone}}, journal = {Annals of clinical and translational neurology}, year = {2026}, doi = {10.64898/2026.02.03.26345302}, url = {https://doi.org/10.64898/2026.02.03.26345302} } @article{daneshvar2011-22050943, author = {Daneshvar, D. H. and Riley, D. O. and Nowinski, C. J. and McKee, A. C. and Stern, R. A. and Cantu, R. C.}, title = {{Long-term consequences: effects on normal development profile after concussion}}, journal = {Physical medicine and rehabilitation clinics of North America}, year = {2011}, doi = {10.1016/j.pmr.2011.08.009}, pmid = {22050943}, url = {https://doi.org/10.1016/j.pmr.2011.08.009} } @article{piers2017-29036819, author = {Piers, R. J. and Devlin, K. N. and Ning, B. and Liu, Y. and Wasserman, B. and Massaro, J. M. and Lamar, M. and Price, C. C. and others}, title = {{Age and Graphomotor Decision Making Assessed with the Digital Clock Drawing Test: The Framingham Heart Study}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2017}, doi = {10.3233/jad-170444}, pmid = {29036819}, url = {https://doi.org/10.3233/jad-170444} } @article{fraser1993-8515277, author = {Fraser, P. E. and Nguyen, J. T. and McLachlan, D. R. and Abraham, C. R. and Kirschner, D. A.}, title = {{Alpha 1-antichymotrypsin binding to Alzheimer A beta peptides is sequence specific and induces fibril disaggregation in vitro}}, journal = {Journal of neurochemistry}, year = {1993}, doi = {10.1111/j.1471-4159.1993.tb03568.x}, pmid = {8515277}, url = {https://doi.org/10.1111/j.1471-4159.1993.tb03568.x} } @article{li2018-28627378, author = {Li, J. and Ogrodnik, M. and Devine, S. and Auerbach, S. and Wolf, P. A. and Au, R.}, title = {{Practical risk score for 5-, 10-, and 20-year prediction of dementia in elderly persons: Framingham Heart Study}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2018}, doi = {10.1016/j.jalz.2017.04.013}, pmid = {28627378}, url = {https://doi.org/10.1016/j.jalz.2017.04.013} } @article{wolf2012-22213410, author = {Wolf, P. A.}, title = {{Contributions of the Framingham Heart Study to stroke and dementia epidemiologic research at 60 years}}, journal = {Archives of neurology}, year = {2012}, doi = {10.1001/archneurol.2011.977}, pmid = {22213410}, url = {https://doi.org/10.1001/archneurol.2011.977} } @article{lee2025-40042467, author = {Lee, Haeok and Mlombe, Yohannie B. and Song, Yeunjoo E. and Yang, Hyun‐Sik and Phiri, Tiwonge Elisa and Maseke, Joseph and Bauleni, Esther M. and Jun, Gyungah and others}, title = {{Dementia prevalence and risk factors in people with and without HIV in Malawi: A medical record review}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70009}, pmid = {40042467}, url = {https://doi.org/10.1002/alz.70009} } @article{holick2011-21415774, author = {Holick, M. F.}, title = {{Vitamin D: a d-lightful solution for health}}, journal = {Journal of investigative medicine : the official publication of the American Federation for Clinical Research}, year = {2011}, doi = {10.2310/jim.0b013e318214ea2d}, pmid = {21415774}, url = {https://doi.org/10.2310/jim.0b013e318214ea2d} } @article{chung2018-29274321, author = {Chung, J. and Wang, X. and Maruyama, T. and Ma, Y. and Zhang, X. and Mez, J. and Sherva, R. and Takeyama, H. and others}, title = {{Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2018}, doi = {10.1016/j.jalz.2017.11.006}, pmid = {29274321}, url = {https://doi.org/10.1016/j.jalz.2017.11.006} } @article{mckee2006-16783172, author = {McKee, A. C. and Au, R. and Cabral, H. J. and Kowall, N. W. and Seshadri, S. and Kubilus, C. A. and Drake, J. and Wolf, P. A.}, title = {{Visual association pathology in preclinical Alzheimer disease}}, journal = {Journal of neuropathology and experimental neurology}, year = {2006}, doi = {10.1097/00005072-200606000-00010}, pmid = {16783172}, url = {https://doi.org/10.1097/00005072-200606000-00010} } @article{khurshid2026-41857676, author = {Khurshid, Zainab and Tong, Tong and Olayinka, Oluwatosin A and Farrell, John Joseph and Zhu, Congcong and {Alzheimer's Disease Sequencing Project} and Martin, Eden R. and Bush, William S. and others}, title = {{Interactive effects of telomere length and genetic variants on Alzheimer disease risk across multiple ancestral populations}}, journal = {Alzheimer s Research \& Therapy}, year = {2026}, doi = {10.1186/s13195-026-02005-8}, pmid = {41857676}, url = {https://doi.org/10.1186/s13195-026-02005-8} } @article{frank2026-41975557, author = {Frank, Brandon E. and Gurnani, Ashita S. and Hurley, Landon and Guan, Calvin and Andersen, Stacy L. and Devine, Sherral and O’Connor, Maureen K. and Budson, Andrew E. and others}, title = {{Psychometric modeling of Boston process approach data for dementia prediction in the Framingham Heart Study}}, journal = {Journal of the International Neuropsychological Society}, year = {2026}, doi = {10.1017/s1355617726101921}, pmid = {41975557}, url = {https://doi.org/10.1017/s1355617726101921} } @article{rui2025-39853966, author = {Rui, Tongyu and Huang, He‐Zhou and Zheng, Kai and Fan, Hong‐Wei and Zhang, Juan and Guo, Ziyuan and Man, Heng‐Ye and Brazhe, Nadezda A. and others}, title = {{Tau Pathology Drives Disease‐Associated Astrocyte Reactivity in Salt‐Induced Neurodegeneration}}, journal = {Advanced Science}, year = {2025}, doi = {10.1002/advs.202410799}, pmid = {39853966}, url = {https://doi.org/10.1002/advs.202410799} } @article{volicer1990-2146522, author = {Volicer, L. and Crino, P. B.}, title = {{Involvement of free radicals in dementia of the Alzheimer type: a hypothesis}}, journal = {Neurobiology of aging}, year = {1990}, doi = {10.1016/0197-4580(90)90119-k}, pmid = {2146522}, url = {https://doi.org/10.1016/0197-4580(90)90119-k} } @article{nicholas1985-4046581, author = {Nicholas, M. and Obler, L. K. and Albert, M. L. and Helm-Estabrooks, N.}, title = {{Empty speech in Alzheimer's disease and fluent aphasia}}, journal = {Journal of speech and hearing research}, year = {1985}, doi = {10.1044/jshr.2803.405}, pmid = {4046581}, url = {https://doi.org/10.1044/jshr.2803.405} } @article{roscoe2024-c8841b99, author = {Roscoe, Joseph A. and Whitmer, Rachel A. and Gutierrez, Sirena and Eng, Chloe W. and Glymour, M. Maria and DeCarli, Charles S and Barnes, Lisa Laverne and Gavett, Brandon E. and others}, title = {{County‐level indicators of education quality and brain imaging markers of neurodegeneration and vascular injury among racially and ethnically diverse middle‐aged and older adults}}, journal = {Alzheimer s \& Dementia}, year = {2024}, doi = {10.1002/alz.093321}, url = {https://doi.org/10.1002/alz.093321} } @article{libon2025-40262110, author = {Libon, David J. and Swenson, Rodney A. and Langford, Dianne and Cosentino, Stephanie and Price, Catherine C. and Lamar, Melissa and Emrani, Sheina and Au, Rhoda and others}, title = {{Precision neurocognition: An emerging diagnostic paradigm leveraging digital cognitive assessment technology}}, journal = {Journal of Alzheimer s Disease}, year = {2025}, doi = {10.1177/13872877251325725}, pmid = {40262110}, url = {https://doi.org/10.1177/13872877251325725} } @article{katsinelos2025-41260337, author = {Katsinelos, Panagiotis and Lövestam, Sofia and Qi, Chao and Falcon, Benjamin and Macdonald, Jennifer A. and Stephenson, Gabriel and Ghetti, Bernardino Francesco and McKee, Ann Carolyn and others}, title = {{Seeding biosensor cell line that reproduces the Alzheimer tau fold}}, journal = {Journal of Biological Chemistry}, year = {2025}, doi = {10.1016/j.jbc.2025.110952}, pmid = {41260337}, url = {https://doi.org/10.1016/j.jbc.2025.110952} } @article{han2025-40239644, author = {Han, Xudong and Zhang, Yichi and Petrosky, Jillian N and Bald, Sarah and Sherva, Richard and Labadorf, Adam Thomas and Cherry, Jonathan D. and Chung, Jaeyoon and others}, title = {{A structural haplotype in the 17q21.31 MAPT region is associated with increased risk for chronic traumatic encephalopathy endophenotypes}}, journal = {Cell Reports Medicine}, year = {2025}, doi = {10.1016/j.xcrm.2025.102084}, pmid = {40239644}, url = {https://doi.org/10.1016/j.xcrm.2025.102084} } @article{davies1997-9258891, author = {Davies, T. A. and Long, H. J. and Sgro, K. and Rathbun, W. H. and McMenamin, M. E. and Seetoo, K. and Tibbles, H. and Billingslea, A. M. and others}, title = {{Activated Alzheimer disease platelets retain more beta amyloid precursor protein}}, journal = {Neurobiology of aging}, year = {1997}, doi = {10.1016/s0197-4580(97)00013-4}, pmid = {9258891}, url = {https://doi.org/10.1016/s0197-4580(97)00013-4} } @article{mcnamara1992-1547468, author = {McNamara, P. and Obler, L. K. and Au, R. and Durso, R. and Albert, M. L.}, title = {{Speech monitoring skills in Alzheimer's disease, Parkinson's disease, and normal aging}}, journal = {Brain and language}, year = {1992}, doi = {10.1016/0093-934x(92)90055-j}, pmid = {1547468}, url = {https://doi.org/10.1016/0093-934x(92)90055-j} } @article{daigle1993-8265668, author = {Daigle, I. and Li, C.}, title = {{apl-1, a Caenorhabditis elegans gene encoding a protein related to the human beta-amyloid protein precursor}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {1993}, doi = {10.1073/pnas.90.24.12045}, pmid = {8265668}, url = {https://doi.org/10.1073/pnas.90.24.12045} } @article{benchek2025-41447272, author = {Benchek, Penelope H. and Reitz, Christiane and Dietrich, Sven‐Thorsten and Ray, Nicholas R. and Hamilton‐Nelson, Kara L. and Beecham, Gary W and Vance, Jeffery M. and Byrd, Goldie S. and others}, title = {{Heterogeneity in the Genetic Architecture of Alzheimer disease (AD) across Ancestry Groups}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz70855_107285}, pmid = {41447272}, url = {https://doi.org/10.1002/alz70855_107285} } @article{temple2026-41709460, author = {Temple, Seth D and Chapman, Nicola H. and Choi, Seung Min and DeStefano, Anita L. and Thornton, Timothy A. and Wijsman, Ellen Marie and Blue, Elizabeth}, title = {{Multiple-testing corrections in case-control studies using identity-by-descent segments}}, journal = {The American Journal of Human Genetics}, year = {2026}, doi = {10.1016/j.ajhg.2026.01.013}, pmid = {41709460}, url = {https://doi.org/10.1016/j.ajhg.2026.01.013} } @article{wang2025-41326294, author = {Wang, Liming and Glass, Jim and Kourtis, Lampros C. and Au, Rhoda}, title = {{Multi-modal data analysis for early detection of alzheimer’s disease and related dementias}}, journal = {The Journal of Prevention of Alzheimer s Disease}, year = {2025}, doi = {10.1016/j.tjpad.2025.100399}, pmid = {41326294}, url = {https://doi.org/10.1016/j.tjpad.2025.100399} } @article{boller1977-886353, author = {Boller, F. and Boller, M. and Gilbert, J.}, title = {{Familial idiopathic cerebral calcifications}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {1977}, doi = {10.1136/jnnp.40.3.280}, pmid = {886353}, url = {https://doi.org/10.1136/jnnp.40.3.280} } @article{au2017-29376667, author = {Au, R. and Piers, R. J. and Devine, S.}, title = {{How technology is reshaping cognitive assessment: Lessons from the Framingham Heart Study}}, journal = {Neuropsychology}, year = {2017}, doi = {10.1037/neu0000411}, pmid = {29376667}, url = {https://doi.org/10.1037/neu0000411} } @article{george2025-41230793, author = {George, Grace C. and Keller, Sarah A. and Abner, Erin L. and Adar, Sara Dubowsky and Alosco, Michael Louis and Apostolova, Liana G. and Bakulski, Kelly M. and Barnes, Lisa Laverne and others}, title = {{The Neighborhoods Study: Examining the social exposome in Alzheimer's disease and related dementias}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70810}, pmid = {41230793}, url = {https://doi.org/10.1002/alz.70810} } @article{zheng2025-40182055, author = {Zheng, Chao and Xia, Weiming and Zhang, Jianhua}, title = {{Rock inhibitors in Alzheimer’s disease}}, journal = {Frontiers in Aging}, year = {2025}, doi = {10.3389/fragi.2025.1547883}, pmid = {40182055}, url = {https://doi.org/10.3389/fragi.2025.1547883} } @article{kurniansyah2025-41434242, author = {Kurniansyah, Nuzulul and Tasaki, Shinya and Zhu, Congcong and Farrell, John Joseph and Rehman, Habbiburr and Sherva, Richard and Hauger, Richard L. and Merritt, Victoria C. and others}, title = {{Hormone replacement therapy in women and vascular risk factors modify the association of a multi‐ancestry polygenic risk score with Alzheimer disease and related traits}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz70861_108536}, pmid = {41434242}, url = {https://doi.org/10.1002/alz70861_108536} } @article{kapoor2025-41445135, author = {Kapoor, Arushi and Carter, Jeffrey and Landau, Emma and Napolitan, Chris and Simone, Laura and Jarzylo, Larissa A. and Budson, Andrew E.}, title = {{Examining Barriers and Strategies to Improve Alzheimer's Disease Care in the Veterans Affairs Setting}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz70858_102944}, pmid = {41445135}, url = {https://doi.org/10.1002/alz70858_102944} } @article{oneill2025-40706314, author = {O’Neill, Nicholas K. and Kurniansyah, Nuzulul and Zhu, Congcong and Olayinka, Oluwatosin A and Mayeux, Richard P and Haines, Jonathan L. and Pericak‐Vance, Margaret Ann and Wang, Li-San and others}, title = {{Multi-omic derived cell-type specific Alzheimer disease polygenic risk scores}}, journal = {Neurobiology of Aging}, year = {2025}, doi = {10.1016/j.neurobiolaging.2025.07.009}, pmid = {40706314}, url = {https://doi.org/10.1016/j.neurobiolaging.2025.07.009} } @article{graff2025-41128446, author = {Graff, Rebecca E. and Chen, Dorothy M. and Swinnerton, Kaitlin N. and Ackley, Sarah F. and Ospina‐Romero, Monica and Zimmerman, Scott C. and Wang, Jingxuan and Buto, Peter T. and others}, title = {{Evaluation of Polygenic Risk Scores for a Possible Genetic Basis of the Inverse Association Between Cancer and Cognitive Decline}}, journal = {Alzheimer Disease \& Associated Disorders}, year = {2025}, doi = {10.1097/wad.0000000000000696}, pmid = {41128446}, url = {https://doi.org/10.1097/wad.0000000000000696} } @article{rocco1997-9194955, author = {Rocco, F. J. and Cronin-Golomb, A. and Lai, F.}, title = {{Alzheimer-like visual deficits in Down syndrome}}, journal = {Alzheimer disease and associated disorders}, year = {1997}, doi = {10.1097/00002093-199706000-00005}, pmid = {9194955}, url = {https://doi.org/10.1097/00002093-199706000-00005} } @article{tang2026-42218841, author = {Tang, Rongxiang and Elman, Jeremy A. and Hunt, J R and Eyler, Lisa T. and Bell, Tyler Reed and Buchholz, Erik J. and Fennema‐Notestine, Christine and Lyons, Michael J. and others}, title = {{Neighborhood disadvantage and cognitive function in older adults: The moderating role of young adult general cognitive ability}}, journal = {Health \& Place}, year = {2026}, doi = {10.1016/j.healthplace.2026.103690}, pmid = {42218841}, url = {https://doi.org/10.1016/j.healthplace.2026.103690} } @article{cole2025-41511892, author = {Cole, Keith R. and Gifford, Katherine A. and Davidson, Leslie}, title = {{Relationship of cognition and structured grocery shopping in older adults with and without mild cognitive impairment}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz70856_107505}, pmid = {41511892}, url = {https://doi.org/10.1002/alz70856_107505} } @article{tang2026-42178222, author = {Tang, Rongxiang and Beck, Asad I. and Gustavson, Daniel E. and Eyler, Lisa T. and Elman, Jeremy A. and Bell, Tyler Reed and Buchholz, Erik J. and Hunt, J R and others}, title = {{Young adult urbanicity, late midlife neighborhood disadvantage, and cognitive functioning in community-dwelling older men}}, journal = {The Journals of Gerontology Series B}, year = {2026}, doi = {10.1093/geronb/gbag093}, pmid = {42178222}, url = {https://doi.org/10.1093/geronb/gbag093} } @article{kase1991-2059410, author = {Kase, Carlos S.}, title = {{Epidemiology of Multi-Infarct Dementia}}, journal = {Alzheimer Disease \& Associated Disorders}, year = {1991}, doi = {10.1097/00002093-199100520-00004}, pmid = {2059410}, url = {https://doi.org/10.1097/00002093-199100520-00004} } @article{sinex1986-2948082, author = {Sinex, F. M.}, title = {{The mortality of adults with Down syndrome as a function of age}}, journal = {Mechanisms of ageing and development}, year = {1986}, doi = {10.1016/0047-6374(86)90088-6}, pmid = {2948082}, url = {https://doi.org/10.1016/0047-6374(86)90088-6} } @article{wang2026-dbbc063a, author = {Wang, J. and Pederson, A. M. and Flanders, M. D. and Choi, M. and Buto, P. and Sims, K. D. and Chen, R. and Couch, E. and others}, title = {{Education and Alzheimer Disease Genetic Risk in Associations of GLP-1 Receptor Agonists With Dementia Among Adults With Type 2 Diabetes}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.09.04.26362304}, url = {https://doi.org/10.64898/2026.09.04.26362304} } @article{manchanda2026-68b7c246, author = {Manchanda, R. and Pinheiro, A. and Aparicio, H. J. and Lioutas, V.-A. and Beiser, A. S. and Sisto, J. and Ekenze, O. and Benjamin and others}, title = {{Cerebral Small Vessel Disease and Risk of Cardiovascular Events and All-Cause Mortality: The Framingham Heart Study}}, journal = {medRxiv (preprint)}, year = {2026}, doi = {10.64898/2026.09.01.26361997}, url = {https://doi.org/10.64898/2026.09.01.26361997} } @article{zekialhazzouri2026-3687f28d, author = {Zeki Al Hazzouri, A. and Mehio Sibai, A. and Bassil, D. T. and Glymour, M. M. and Manly, J. J. and Abi Chahine, M. and Chehabeddine, L. and Bekdache and others}, title = {{Late Life Learning, Cognition, and Aging: A Longitudinal study of middle and older-aged adults in Beirut, Lebanon (3LC study)}}, journal = {medRxiv (preprint)}, year = {2026}, doi = {10.64898/2026.09.10.26362603}, url = {https://doi.org/10.64898/2026.09.10.26362603} } @article{ma2026-a6a56bb0, author = {Ma, P. and Zhou, J. and Cheng, Y. and McGeary, J. E. and Taveira, T. H. and Ahmed, A. and Wu, W.-C. and Zamrini and others}, title = {{Varenicline as a Repurposable Drug Candidate for ADRD Prevention}}, journal = {medRxiv (preprint)}, year = {2026}, doi = {10.64898/2026.09.17.26363232}, url = {https://doi.org/10.64898/2026.09.17.26363232} }