% alzhub.org library filter % Source: https://alzhub.org/research?design=rct % 476 entries, in the order the page lists them. Built from alzhub.org's own records. % 2 entries have no readable author in the source record and carry no author field. @article{brodaty2025-39875685, author = {Brodaty, Henry and Chau, Tiffany and Heffernan, Megan and Ginige, Jeewani A and Andrews, Gavin and Millard, Michael and Sachdev, Perminder S and Anstey, Kaarin J and others}, title = {{An online multidomain lifestyle intervention to prevent cognitive decline in at-risk older adults: a randomized controlled trial}}, journal = {Nature medicine}, year = {2025}, doi = {10.1038/s41591-024-03351-6}, pmid = {39875685}, url = {https://doi.org/10.1038/s41591-024-03351-6} } @article{edwards2017-29201994, author = {Edwards, J. D. and Xu, H. and Clark, D. O. and Guey, L. T. and Ross, L. A. and Unverzagt, F. W.}, title = {{Speed of processing training results in lower risk of dementia}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2017}, doi = {10.1016/j.trci.2017.09.002}, pmid = {29201994}, url = {https://doi.org/10.1016/j.trci.2017.09.002} } @article{oki2024-39229900, author = {Oki, Y. and Osaki, T. and Kumagai, R. and Murata, S. and Encho, H. and Ono, R. and Yasuda, H. and Kowa, H.}, title = {{An 18-month multimodal intervention trial for preventing dementia: J-MINT PRIME Tamba}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.14170}, pmid = {39229900}, url = {https://doi.org/10.1002/alz.14170} } @article{kim2026-42475653, author = {Kim, Da Ae and Lee, Sun Min and Sun, Kyunghwa and Park, Ji Hyun and Park, Yoo Kyoung and Jeong, Jee Hyang and Hong, Chang Hyung and Jung, Jiwoo and others}, title = {{Multidomain Lifestyle Intervention in Mild Cognitive Impairment: Subgroup Analysis of the SUPERBRAIN-MEET Randomized Trial}}, journal = {Neurology}, year = {2026}, doi = {10.1212/wnl.0000000000218297}, pmid = {42475653}, url = {https://doi.org/10.1212/wnl.0000000000218297} } @article{barnes2023-37466280, author = {Barnes, L. L. and Dhana, K. and Liu, X. and Carey, V. J. and Ventrelle, J. and Johnson, K. and others}, title = {{Trial of the MIND Diet for Prevention of Cognitive Decline in Older Persons}}, journal = {New England Journal of Medicine}, year = {2023}, doi = {10.1056/NEJMoa2302368}, pmid = {37466280}, url = {https://doi.org/10.1056/NEJMoa2302368} } @article{ngandu2015-25771249, author = {Ngandu, T. and Lehtisalo, J. and Solomon, A. and Levälahti, E. and Ahtiluoto, S. and Antikainen, R. and Bäckman, L. and Hänninen, T. and others}, title = {{A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial}}, journal = {Lancet (London, England)}, year = {2015}, doi = {10.1016/s0140-6736(15)60461-5}, pmid = {25771249}, url = {https://doi.org/10.1016/s0140-6736(15)60461-5} } @article{courtright2024-38227032, author = {Courtright, K. R. and Madden, V. and Bayes, B. and Chowdhury, M. and Whitman, C. and Small, D. S. and Harhay, M. O. and Parra, S. and others}, title = {{Default Palliative Care Consultation for Seriously Ill Hospitalized Patients: A Pragmatic Cluster Randomized Trial}}, journal = {JAMA}, year = {2024}, doi = {10.1001/jama.2023.25092}, pmid = {38227032}, url = {https://doi.org/10.1001/jama.2023.25092} } @article{lin2023-37478886, author = {Lin, F. R. and Pike, JR. and Albert, M. S. and Arnold, M. and Burgard, S. and Chisolm, T. and Couper, D. and Deal, J. A. and others}, title = {{Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial}}, journal = {Lancet (London, England)}, year = {2023}, doi = {10.1016/s0140-6736(23)01406-x}, pmid = {37478886}, url = {https://doi.org/10.1016/s0140-6736(23)01406-x} } @article{verghese2021-34522910, author = {Verghese, Joe and Mahoney, Jeannette R and Ayers, Emmeline and Ambrose, Anne and Wang, Cuiling and Holtzer, Roee}, title = {{Computerised cognitive remediation to enhance mobility in older adults: a single-blind, single-centre, randomised trial}}, journal = {The lancet. Healthy longevity}, year = {2021}, doi = {10.1016/s2666-7568(21)00173-2}, pmid = {34522910}, url = {https://doi.org/10.1016/s2666-7568(21)00173-2} } @article{vanasbroeck2024-38759017, author = {Van Asbroeck, Stephanie and Köhler, Sebastian and Wimmers, Sophie C P M and Muris, Jean W M and van Boxtel, Martin P J and Deckers, Kay}, title = {{Multidomain Dementia Risk Reduction in Primary Care is Feasible: A Proof-of-concept study}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2024}, doi = {10.3233/jad-240229}, pmid = {38759017}, url = {https://doi.org/10.3233/jad-240229} } @article{simone2024-37930366, author = {Simone, Tamar and Peltz, Carrie and Rosenberg, Dori E and Barnes, Deborah E and Fleckenstein, Lynn E and Dublin, Sascha and Yaffe, Kristine}, title = {{The Impact of Pandemic-Related Restrictions on Dementia Risk Factors in Older Adults}}, journal = {Journal of applied gerontology : the official journal of the Southern Gerontological Society}, year = {2024}, doi = {10.1177/07334648231210671}, pmid = {37930366}, url = {https://doi.org/10.1177/07334648231210671} } @article{moon2021-34148030, author = {Moon, S. Y. and Hong, C. H. and Jeong, J. H. and Park, Y. K. and Na, H. R. and Song, H. S. and Kim, B. C. and Park, K. W. and others}, title = {{Facility-based and home-based multidomain interventions including cognitive training, exercise, diet, vascular risk management, and motivation for older adults: a randomized controlled feasibility trial}}, journal = {Aging}, year = {2021}, doi = {10.18632/aging.203213}, pmid = {34148030}, url = {https://doi.org/10.18632/aging.203213} } @article{hsu2025-40316479, author = {Hsu, C. W. and Hsu, T. W. and Kao, Y. C. and Lin, Y. H. and Thompson, T. and Carvalho, A. F. and Stubbs, B. and Tseng, P. T. and others}, title = {{The efficacy and safety of anti-amyloid monoclonal antibody versus acetylcholinesterase inhibitor with an in-depth analysis across genotypes and disease stages: a systematic review and meta-analysis}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2025}, doi = {10.1016/j.tjpad.2025.100195}, pmid = {40316479}, url = {https://doi.org/10.1016/j.tjpad.2025.100195} } @article{kehoe2021-34687634, author = {Kehoe, Patrick Gavin and Turner, Nicholas and Howden, Beth and Jarutyte, Lina and Clegg, Shona Louise and Malone, Ian Brian and Barnes, Josephine and Nielsen, Casper and others}, title = {{Safety and efficacy of losartan for the reduction of brain atrophy in clinically diagnosed Alzheimer's disease (the RADAR trial): a double-blind, randomised, placebo-controlled, phase 2 trial}}, journal = {The Lancet. Neurology}, year = {2021}, doi = {10.1016/s1474-4422(21)00263-5}, pmid = {34687634}, url = {https://doi.org/10.1016/s1474-4422(21)00263-5} } @article{liu2025-40806132, author = {Liu, Yuxi and Fowler, Hailie and Wang, Dong D and Barnes, Lisa L and Cornelis, Marilyn C}, title = {{Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Trial: Genetic Resource for Precision Nutrition}}, journal = {Nutrients}, year = {2025}, doi = {10.3390/nu17152548}, pmid = {40806132}, url = {https://doi.org/10.3390/nu17152548} } @article{vallspedret2015-25961184, author = {Valls-Pedret, C. and Sala-Vila, A. and Serra-Mir, M. and Corella, D. and de la Torre, R. and MÁ, Martínez-González and others}, title = {{Mediterranean Diet and Age-Related Cognitive Decline: A Randomized Clinical Trial}}, journal = {JAMA Internal Medicine}, year = {2015}, doi = {10.1001/jamainternmed.2015.1668}, pmid = {25961184}, url = {https://doi.org/10.1001/jamainternmed.2015.1668} } @article{he2025-40258956, author = {He, J. and Zhao, C. and Zhong, S. and Ouyang, N. and Sun, G. and Qiao, L. and others}, title = {{Blood pressure reduction and all-cause dementia in people with uncontrolled hypertension: an open-label, blinded-endpoint, cluster-randomized trial}}, journal = {Nature Medicine}, year = {2025}, doi = {10.1038/s41591-025-03616-8}, pmid = {40258956}, url = {https://doi.org/10.1038/s41591-025-03616-8} } @article{thunborg2024-38812047, author = {Thunborg, C. and Wang, R. and Rosenberg, A. and Sindi, S. and Andersen, P. and Andrieu, S. and Broersen, L. M. and Coley, N. and others}, title = {{Integrating a multimodal lifestyle intervention with medical food in prodromal Alzheimer's disease: the MIND-ADmini randomized controlled trial}}, journal = {Alzheimer's research \& therapy}, year = {2024}, doi = {10.1186/s13195-024-01468-x}, pmid = {38812047}, url = {https://doi.org/10.1186/s13195-024-01468-x} } @article{gassoumis2024-37791406, author = {Gassoumis, Zachary D and Martinez, Julia M and Yonashiro-Cho, Jeanine and Mosqueda, Laura and Hou, Anthony and Han, S Duke and Olsen, Bonnie and Louis, Anat and others}, title = {{Comprehensive Older Adult and Caregiver Help (COACH): A person-centered caregiver intervention prevents elder mistreatment}}, journal = {Journal of the American Geriatrics Society}, year = {2024}, doi = {10.1111/jgs.18597}, pmid = {37791406}, url = {https://doi.org/10.1111/jgs.18597} } @article{sapra2025-40129751, author = {Sapra, Mamta and Hagemann, Lauren and Luci, Katherine and Savla, Jyoti}, title = {{A mindfulness-based multicomponent caregiver intervention (PAACC): objectives, study design, and cohort description}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2025}, doi = {10.1002/trc2.70064}, pmid = {40129751}, url = {https://doi.org/10.1002/trc2.70064} } @article{moayyedi2019-31152740, author = {Moayyedi, P. and Eikelboom, J. W. and Bosch, J. and Connolly, S. J. and Dyal, L. and Shestakovska, O. and Leong, D. and Anand, S. S. and others}, title = {{Safety of Proton Pump Inhibitors Based on a Large, Multi-Year, Randomized Trial of Patients Receiving Rivaroxaban or Aspirin}}, journal = {Gastroenterology}, year = {2019}, doi = {10.1053/j.gastro.2019.05.056}, pmid = {31152740}, url = {https://doi.org/10.1053/j.gastro.2019.05.056} } @article{zulke2024-37768074, author = {Zülke, A. E. and Pabst, A. and Luppa, M. and Roehr, S. and Seidling, H. and Oey, A. and Cardona, M. I. and Blotenberg, I. and others}, title = {{A multidomain intervention against cognitive decline in an at-risk-population in Germany: Results from the cluster-randomized AgeWell.de trial}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.13486}, pmid = {37768074}, url = {https://doi.org/10.1002/alz.13486} } @article{doniger2018-29955655, author = {Doniger, G. M. and Beeri, M. S. and Bahar-Fuchs, A. and Gottlieb, A. and Tkachov, A. and Kenan, H. and Livny, A. and Bahat, Y. and others}, title = {{Virtual reality-based cognitive-motor training for middle-aged adults at high Alzheimer's disease risk: A randomized controlled trial}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2018}, doi = {10.1016/j.trci.2018.02.005}, pmid = {29955655}, url = {https://doi.org/10.1016/j.trci.2018.02.005} } @article{desoutobarreto2021-33569560, author = {de Souto Barreto, P. and Pothier, K. and Soriano, G. and Lussier, M. and Bherer, L. and Guyonnet, S. and Piau, A. and Ousset, P. J. and others}, title = {{A Web-Based Multidomain Lifestyle Intervention for Older Adults: The eMIND Randomized Controlled Trial}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2021}, doi = {10.14283/jpad.2020.70}, pmid = {33569560}, url = {https://doi.org/10.14283/jpad.2020.70} } @article{xu2022-35098972, author = {Xu, X. and Chew, K. A. and Wong, Z. X. and Phua, A. K. S. and Chong, E. J. Y. and Teo, C. K. L. and Sathe, N. and Chooi, Y. C. and others}, title = {{The SINgapore GERiatric Intervention Study to Reduce Cognitive Decline and Physical Frailty (SINGER): Study Design and Protocol}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2022}, doi = {10.14283/jpad.2022.5}, pmid = {35098972}, url = {https://doi.org/10.14283/jpad.2022.5} } @article{eggink2021-34108173, author = {Eggink, E. and Hafdi, M. and Hoevenaar-Blom, M. P. and Song, M. and Andrieu, S. and Barnes, L. E. and Birck, C. and Brooks, R. L. and others}, title = {{Prevention of dementia using mobile phone applications (PRODEMOS): protocol for an international randomised controlled trial}}, journal = {BMJ open}, year = {2021}, doi = {10.1136/bmjopen-2021-049762}, pmid = {34108173}, url = {https://doi.org/10.1136/bmjopen-2021-049762} } @article{deal2017-29067347, author = {Deal, J. A. and Albert, M. S. and Arnold, M. and Bangdiwala, S. I. and Chisolm, T. and Davis, S. and Eddins, A. and Glynn, N. W. and others}, title = {{A randomized feasibility pilot trial of hearing treatment for reducing cognitive decline: Results from the Aging and Cognitive Health Evaluation in Elders Pilot Study}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2017}, doi = {10.1016/j.trci.2017.06.003}, pmid = {29067347}, url = {https://doi.org/10.1016/j.trci.2017.06.003} } @article{lautenschlager2008-18768414, author = {Lautenschlager, N. T. and Cox, K. L. and Flicker, L. and Foster, J. K. and van Bockxmeer, F. M. and Xiao, J. and Greenop, K. R. and Almeida, O. P.}, title = {{Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial}}, journal = {JAMA}, year = {2008}, doi = {10.1001/jama.300.9.1027}, pmid = {18768414}, url = {https://doi.org/10.1001/jama.300.9.1027} } @article{ngandu2022-34668644, author = {Ngandu, T. and Lehtisalo, J. and Korkki, S. and Solomon, A. and Coley, N. and Antikainen, R. and Bäckman, L. and Hänninen, T. and others}, title = {{The effect of adherence on cognition in a multidomain lifestyle intervention (FINGER)}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2022}, doi = {10.1002/alz.12492}, pmid = {34668644}, url = {https://doi.org/10.1002/alz.12492} } @article{kwan2024-39259959, author = {Kwan, R. Y. C. and Liu, J. and Sin, O. S. K. and Fong, K. N. K. and Qin, J. and Wong, J. C. Y. and Lai, C.}, title = {{Effects of Virtual Reality Motor-Cognitive Training for Older People With Cognitive Frailty: Multicentered Randomized Controlled Trial}}, journal = {Journal of medical Internet research}, year = {2024}, doi = {10.2196/57809}, pmid = {39259959}, url = {https://doi.org/10.2196/57809} } @article{ballard2018-29408901, author = {Ballard, C. and Corbett, A. and Orrell, M. and Williams, G. and Moniz-Cook, E. and Romeo, R. and Woods, B. and Garrod, L. and others}, title = {{Impact of person-centred care training and person-centred activities on quality of life, agitation, and antipsychotic use in people with dementia living in nursing homes: A cluster-randomised controlled trial}}, journal = {PLoS medicine}, year = {2018}, doi = {10.1371/journal.pmed.1002500}, pmid = {29408901}, url = {https://doi.org/10.1371/journal.pmed.1002500} } @article{rogalski2025-39588869, author = {Rogalski, Emily and Bona, Matthew and Esparza, Marissa and Mooney, Aimee and Fried-Oken, Melanie and Rademaker, Alfred and Roberts, Angela}, title = {{Communication Bridge-2 randomized controlled trial: Recruitment and baseline features}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.14168}, pmid = {39588869}, url = {https://doi.org/10.1002/alz.14168} } @article{lorenzon2025-40998691, author = {Lorenzon, Giulia and Marseglia, Anna and Mohanty, Rosaleena and Lehtisalo, Jenni and Poulakis, Konstantinos and Ngandu, Tiia and Solomon, Alina and Kivipelto, Miia and others}, title = {{Brain patterns and risk factors in the FINGER RCT multimodal lifestyle intervention}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2025}, doi = {10.1016/j.tjpad.2025.100390}, pmid = {40998691}, url = {https://doi.org/10.1016/j.tjpad.2025.100390} } @article{li2024-38706275, author = {Li, S-Y and Xie, X-Y and Liu, D and Cheng, G-R and Hu, F-F and Zeng, D-Y and Chen, X-C and Jia, L-F and others}, title = {{China Initiative for Multi-Domain Intervention (CHINA-IN-MUDI) to Prevent Cognitive Decline: Study Design and Progress}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2024}, doi = {10.14283/jpad.2024.63}, pmid = {38706275}, url = {https://doi.org/10.14283/jpad.2024.63} } @article{reuben2025-39878968, author = {Reuben, D. B. and Gill, T. M. and Stevens, A. and Williamson, J. and Volpi, E. and Lichtenstein, M. and Jennings, L. A. and others}, title = {{Health System, Community-Based, or Usual Dementia Care for Persons With Dementia and Caregivers: The D-CARE Randomized Clinical Trial}}, journal = {JAMA}, year = {2025}, doi = {10.1001/jama.2024.25056}, pmid = {39878968}, url = {https://doi.org/10.1001/jama.2024.25056} } @article{mollvancharante2016-27474376, author = {Moll van Charante, E. P. and Richard, E. and Eurelings, L. S. and van Dalen, J. W. and Ligthart, S. A. and van Bussel, E. F. and Hoevenaar-Blom, M. P. and Vermeulen, M. and others}, title = {{Effectiveness of a 6-year multidomain vascular care intervention to prevent dementia (preDIVA): a cluster-randomised controlled trial}}, journal = {Lancet (London, England)}, year = {2016}, doi = {10.1016/s0140-6736(16)30950-3}, pmid = {27474376}, url = {https://doi.org/10.1016/s0140-6736(16)30950-3} } @article{liang2021-33765656, author = {Liang, C. K. and Lee, W. J. and Hwang, A. C. and Lin, C. S. and Chou, M. Y. and Peng, L. N. and Lin, M. H. and Chen, L. K.}, title = {{Efficacy of Multidomain Intervention Against Physio-cognitive Decline Syndrome: A Cluster-randomized Trial}}, journal = {Archives of gerontology and geriatrics}, year = {2021}, doi = {10.1016/j.archger.2021.104392}, pmid = {33765656}, url = {https://doi.org/10.1016/j.archger.2021.104392} } @article{ponvel2021-34092633, author = {Ponvel, P. and Shahar, S. and Singh, D. K. A. and Ludin, A. F. M. and Rajikan, R. and Rajab, N. F. and Ai-Vyrn, C. and Din, N. C. and others}, title = {{Multidomain Intervention for Reversal of Cognitive Frailty, Towards a Personalized Approach (AGELESS Trial): Study Design}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2021}, doi = {10.3233/jad-201607}, pmid = {34092633}, url = {https://doi.org/10.3233/jad-201607} } @article{goldberg2013-23819964, author = {Goldberg, S. E. and Bradshaw, L. E. and Kearney, F. C. and Russell, C. and Whittamore, K. H. and Foster, P. E. and Mamza, J. and Gladman, JR. and others}, title = {{Care in specialist medical and mental health unit compared with standard care for older people with cognitive impairment admitted to general hospital: randomised controlled trial (NIHR TEAM trial)}}, journal = {BMJ (Clinical research ed.)}, year = {2013}, doi = {10.1136/bmj.f4132}, pmid = {23819964}, url = {https://doi.org/10.1136/bmj.f4132} } @article{volandes2009-19477893, author = {Volandes, A. E. and Paasche-Orlow, M. K. and Barry, M. J. and Gillick, M. R. and Minaker, K. L. and Chang, Y. and Cook, E. F. and Abbo, E. D. and others}, title = {{Video decision support tool for advance care planning in dementia: randomised controlled trial}}, journal = {BMJ (Clinical research ed.)}, year = {2009}, doi = {10.1136/bmj.b2159}, pmid = {19477893}, url = {https://doi.org/10.1136/bmj.b2159} } @article{tilburgs2020-31759901, author = {Tilburgs, B. and Koopmans, R. and Vernooij-Dassen, M. and Adang, E. and Schers, H. and Teerenstra, S. and van de Pol, M. and Smits, C. and others}, title = {{Educating Dutch General Practitioners in Dementia Advance Care Planning: A Cluster Randomized Controlled Trial}}, journal = {Journal of the American Medical Directors Association}, year = {2020}, doi = {10.1016/j.jamda.2019.09.010}, pmid = {31759901}, url = {https://doi.org/10.1016/j.jamda.2019.09.010} } @article{grudzen2019-30813112, author = {Grudzen, C. R. and Shim, D. J. and Schmucker, A. M. and Cho, J. and Goldfeld, K. S. and {EMPallA Investigators}}, title = {{Emergency Medicine Palliative Care Access (EMPallA): protocol for a multicentre randomised controlled trial comparing the effectiveness of specialty outpatient versus nurse-led telephonic palliative care of older adults with advanced illness}}, journal = {BMJ open}, year = {2019}, doi = {10.1136/bmjopen-2018-025692}, pmid = {30813112}, url = {https://doi.org/10.1136/bmjopen-2018-025692} } @article{beernaert2017-28526493, author = {Beernaert, K. and Smets, T. and Cohen, J. and Verhofstede, R. and Costantini, M. and Eecloo, K. and Van Den Noortgate, N. and Deliens, L.}, title = {{Improving comfort around dying in elderly people: a cluster randomised controlled trial}}, journal = {Lancet (London, England)}, year = {2017}, doi = {10.1016/s0140-6736(17)31265-5}, pmid = {28526493}, url = {https://doi.org/10.1016/s0140-6736(17)31265-5} } @article{solopova2023-38086820, author = {Solopova, E. and Romero-Fernandez, W. and Harmsen, H. and Ventura-Antunes, L. and Wang, E. and Shostak, A. and Maldonado, J. and Donahue, M. J. and others}, title = {{Fatal iatrogenic cerebral β-amyloid-related arteritis in a woman treated with lecanemab for Alzheimer's disease}}, journal = {Nature communications}, year = {2023}, doi = {10.1038/s41467-023-43933-5}, pmid = {38086820}, url = {https://doi.org/10.1038/s41467-023-43933-5} } @article{husebo2011-21765198, author = {Husebo, B. S. and Ballard, C. and Sandvik, R. and Nilsen, O. B. and Aarsland, D.}, title = {{Efficacy of treating pain to reduce behavioural disturbances in residents of nursing homes with dementia: cluster randomised clinical trial}}, journal = {BMJ (Clinical research ed.)}, year = {2011}, doi = {10.1136/bmj.d4065}, pmid = {21765198}, url = {https://doi.org/10.1136/bmj.d4065} } @article{kreijkampkaspers2004-15238592, author = {Kreijkamp-Kaspers, S. and Kok, L. and Grobbee, D. E. and de Haan, E. H. and Aleman, A. and Lampe, J. W. and van der Schouw, Y. T.}, title = {{Effect of soy protein containing isoflavones on cognitive function, bone mineral density, and plasma lipids in postmenopausal women: a randomized controlled trial}}, journal = {JAMA}, year = {2004}, doi = {10.1001/jama.292.1.65}, pmid = {15238592}, url = {https://doi.org/10.1001/jama.292.1.65} } @article{study2014-24928805, author = {{PD Med Collaborative Group} and Gray, R. and Ives, N. and Rick, C. and Patel, S. and Gray, A. and Jenkinson, C. and McIntosh, E. and others}, title = {{Long-term effectiveness of dopamine agonists and monoamine oxidase B inhibitors compared with levodopa as initial treatment for Parkinson's disease (PD MED): a large, open-label, pragmatic randomised trial}}, journal = {Lancet (London, England)}, year = {2014}, doi = {10.1016/s0140-6736(14)60683-8}, pmid = {24928805}, url = {https://doi.org/10.1016/s0140-6736(14)60683-8} } @article{yoon2018-30272098, author = {Yoon, D. H. and Lee, J. Y. and Song, W.}, title = {{Effects of Resistance Exercise Training on Cognitive Function and Physical Performance in Cognitive Frailty: A Randomized Controlled Trial}}, journal = {The journal of nutrition, health \& aging}, year = {2018}, doi = {10.1007/s12603-018-1090-9}, pmid = {30272098}, url = {https://doi.org/10.1007/s12603-018-1090-9} } @article{zhang2025-41137085, author = {Zhang, Wenbo and Song, Jiaqi and Zhong, Fuxin and Yu, Wuhan and Qin, Zhangjin and Yang, Ziying and Liu, Jiarui and Wang, Xiaoqin and others}, title = {{Computerized cognitive training enhances cognitive function in Alzheimer's disease by downregulating Ruminococcus-TMAO pathway}}, journal = {Journal of translational medicine}, year = {2025}, doi = {10.1186/s12967-025-07209-4}, pmid = {41137085}, url = {https://doi.org/10.1186/s12967-025-07209-4} } @article{osullivan2022-34183087, author = {O'Sullivan, Julie L and Lech, Sonia and Gellert, Paul and Grittner, Ulrike and Voigt-Antons, Jan-Niklas and Möller, Sebastian and Kuhlmey, Adelheid and Nordheim, Johanna}, title = {{A tablet-based intervention for activating nursing home residents with dementia: results from a cluster-randomized controlled trial}}, journal = {International psychogeriatrics}, year = {2022}, doi = {10.1017/s1041610221000818}, pmid = {34183087}, url = {https://doi.org/10.1017/s1041610221000818} } @article{brill2022-35962371, author = {Brill, Esther and Krebs, Christine and Falkner, Michael and Peter, Jessica and Henke, Katharina and Züst, Marc and Minkova, Lora and Brem, Anna-Katharine and others}, title = {{Can a serious game-based cognitive training attenuate cognitive decline related to Alzheimer's disease? Protocol for a randomized controlled trial}}, journal = {BMC psychiatry}, year = {2022}, doi = {10.1186/s12888-022-04131-7}, pmid = {35962371}, url = {https://doi.org/10.1186/s12888-022-04131-7} } @article{lin2024-38878393, author = {Lin, Ruizhu and Dai, Yaling and Xu, Jianfeng and Xu, Ying and Huang, Jia and Tao, Jing and Liu, Jiao and Yang, Minguang and others}, title = {{Electroacupuncture improves vascular cognitive impairment no dementia: A Randomized Clinical Trial}}, journal = {Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association}, year = {2024}, doi = {10.1016/j.jstrokecerebrovasdis.2024.107788}, pmid = {38878393}, url = {https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.107788} } @article{salisbury2022-34492709, author = {Salisbury, Dereck and Mathiason, Michelle A and Yu, Fang}, title = {{Exercise Dose and Aerobic Fitness Response in Alzheimer's Dementia: Findings from the FIT-AD Trial}}, journal = {International journal of sports medicine}, year = {2022}, doi = {10.1055/a-1639-2307}, pmid = {34492709}, url = {https://doi.org/10.1055/a-1639-2307} } @article{lin2023-37887501, author = {Lin, Xinyao and Moxley, Jerad H and Czaja, Sara J}, title = {{Caring for Dementia Caregivers: Psychosocial Factors Related to Engagement in Self-Care Activities}}, journal = {Behavioral sciences (Basel, Switzerland)}, year = {2023}, doi = {10.3390/bs13100851}, pmid = {37887501}, url = {https://doi.org/10.3390/bs13100851} } @article{lamb2018-29769247, author = {Lamb, S. E. and Sheehan, B. and Atherton, N. and Nichols, V. and Collins, H. and Mistry, D. and others}, title = {{Dementia And Physical Activity (DAPA) trial of moderate to high intensity exercise training for people with dementia: randomised controlled trial}}, journal = {BMJ}, year = {2018}, doi = {10.1136/bmj.k1675}, pmid = {29769247}, url = {https://doi.org/10.1136/bmj.k1675} } @article{barnes2013-23545598, author = {Barnes, D. E. and Santos-Modesitt, W. and Poelke, G. and Kramer, A. F. and Castro, C. and Middleton, L. E. and Yaffe, K.}, title = {{The Mental Activity and eXercise (MAX) trial: a randomized controlled trial to enhance cognitive function in older adults}}, journal = {JAMA internal medicine}, year = {2013}, doi = {10.1001/jamainternmed.2013.189}, pmid = {23545598}, url = {https://doi.org/10.1001/jamainternmed.2013.189} } @article{smith2010-20838622, author = {Smith, A. D. and Smith, S. M. and de Jager, C. A. and Whitbread, P. and Johnston, C. and Agacinski, G. and Oulhaj, A. and Bradley, K. M. and others}, title = {{Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial}}, journal = {PloS one}, year = {2010}, doi = {10.1371/journal.pone.0012244}, pmid = {20838622}, url = {https://doi.org/10.1371/journal.pone.0012244} } @article{law2019-31801630, author = {Law, L. L. F. and Mok, V. C. T. and Yau, M. M. K.}, title = {{Effects of functional tasks exercise on cognitive functions of older adults with mild cognitive impairment: a randomized controlled pilot trial}}, journal = {Alzheimer's research \& therapy}, year = {2019}, doi = {10.1186/s13195-019-0548-2}, pmid = {31801630}, url = {https://doi.org/10.1186/s13195-019-0548-2} } @article{kulmala2021-34448856, author = {Kulmala, J. and Rosenberg, A. and Ngandu, T. and Hemiö, K. and Tenkula, T. and Hyytiä, A. and Vienola, M. and Huhtamäki-Kuoppala, M. and others}, title = {{Facilitators and barriers to implementing lifestyle intervention programme to prevent cognitive decline}}, journal = {European journal of public health}, year = {2021}, doi = {10.1093/eurpub/ckab087}, pmid = {34448856}, url = {https://doi.org/10.1093/eurpub/ckab087} } @article{park2021-34360490, author = {Park, E. A. and Jung, A. R. and Lee, K. A.}, title = {{The Humanoid Robot Sil-Bot in a Cognitive Training Program for Community-Dwelling Elderly People with Mild Cognitive Impairment during the COVID-19 Pandemic: A Randomized Controlled Trial}}, journal = {International journal of environmental research and public health}, year = {2021}, doi = {10.3390/ijerph18158198}, pmid = {34360490}, url = {https://doi.org/10.3390/ijerph18158198} } @article{park2020-32319247, author = {Park, H. K. and Jeong, J. H. and Moon, S. Y. and Park, Y. K. and Hong, C. H. and Na, H. R. and Song, H. S. and Lee, S. M. and others}, title = {{South Korean Study to Prevent Cognitive Impairment and Protect Brain Health Through Lifestyle Intervention in At-Risk Elderly People: Protocol of a Multicenter, Randomized Controlled Feasibility Trial}}, journal = {Journal of clinical neurology (Seoul, Korea)}, year = {2020}, doi = {10.3988/jcn.2020.16.2.292}, pmid = {32319247}, url = {https://doi.org/10.3988/jcn.2020.16.2.292} } @article{bell2022-35901382, author = {Bell, T. R. and Sprague, B. N. and Ross, L. A.}, title = {{Longitudinal associations of pain and cognitive decline in community-dwelling older adults}}, journal = {Psychology and aging}, year = {2022}, doi = {10.1037/pag0000699}, pmid = {35901382}, url = {https://doi.org/10.1037/pag0000699} } @article{tussinghumphreys2017-28600159, author = {Tussing-Humphreys, L. and Lamar, M. and Blumenthal, J. A. and Babyak, M. and Fantuzzi, G. and Blumstein, L. and Schiffer, L. and Fitzgibbon, M. L.}, title = {{Building research in diet and cognition: The BRIDGE randomized controlled trial}}, journal = {Contemporary clinical trials}, year = {2017}, doi = {10.1016/j.cct.2017.06.003}, pmid = {28600159}, url = {https://doi.org/10.1016/j.cct.2017.06.003} } @article{narayan2017-28853000, author = {Narayan, S. W. and Nishtala, P. S.}, title = {{Discontinuation of Preventive Medicines in Older People with Limited Life Expectancy: A Systematic Review}}, journal = {Drugs \& aging}, year = {2017}, doi = {10.1007/s40266-017-0487-1}, pmid = {28853000}, url = {https://doi.org/10.1007/s40266-017-0487-1} } @article{graff2008-18171718, author = {Graff, M. J. and Adang, E. M. and Vernooij-Dassen, M. J. and Dekker, J. and Jönsson, L. and Thijssen, M. and Hoefnagels, W. H. and Rikkert, M. G.}, title = {{Community occupational therapy for older patients with dementia and their care givers: cost effectiveness study}}, journal = {BMJ (Clinical research ed.)}, year = {2008}, doi = {10.1136/bmj.39408.481898.be}, pmid = {18171718}, url = {https://doi.org/10.1136/bmj.39408.481898.be} } @article{macchi2020-31735048, author = {Macchi, Z. A. and Koljack, C. E. and Miyasaki, J. M. and Katz, M. and Galifianakis, N. and Prizer, L. P. and Sillau, S. H. and Kluger, B. M.}, title = {{Patient and caregiver characteristics associated with caregiver burden in Parkinson's disease: a palliative care approach}}, journal = {Annals of palliative medicine}, year = {2020}, doi = {10.21037/apm.2019.10.01}, pmid = {31735048}, url = {https://doi.org/10.21037/apm.2019.10.01} } @article{solomon2021-34151805, author = {Solomon, Alina and Handels, Ron and Wimo, Anders and Antikainen, Riitta and Laatikainen, Tiina and Levälahti, Esko and Peltonen, Markku and Soininen, Hilkka and others}, title = {{Effect of a Multidomain Lifestyle Intervention on Estimated Dementia Risk}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2021}, doi = {10.3233/jad-210331}, pmid = {34151805}, url = {https://doi.org/10.3233/jad-210331} } @article{mauti2026-183d3fda, author = {Mauti, R. and Chouk, C. and Guillot, A. and Peronin, A. and Fargier, P. and Chabaud, P.}, title = {{A clustering approach based on neuropsychological testing to detect early signs of probable MCI among community-dwelling older adults}}, journal = {Frontiers in aging neuroscience}, year = {2026}, doi = {10.64898/2026.07.04.26357270}, url = {https://doi.org/10.64898/2026.07.04.26357270} } @article{sachs2025-39878993, author = {Sachs, G. A. and Johnson, N. M. and Gao, S. and Torke, A. M. and Hickman, S. E. and Pemberton, A. and Vrobel, A. and Pan, M. and West, J. and Kroenke, K.}, title = {{Palliative Care Program for Community-Dwelling Individuals With Dementia and Caregivers: The IN-PEACE Randomized Clinical Trial}}, journal = {JAMA}, year = {2025}, doi = {10.1001/jama.2024.25845}, pmid = {39878993}, url = {https://doi.org/10.1001/jama.2024.25845} } @article{zhou2023-37879942, author = {Zhou, Z. and Ryan, J. and Tonkin, A. M. and Zoungas, S. and Lacaze, P. and Wolfe, R. and Orchard, S. G. and Murray, A. M. and others}, title = {{Association Between Triglycerides and Risk of Dementia in Community-Dwelling Older Adults: A Prospective Cohort Study}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000207923}, pmid = {37879942}, url = {https://doi.org/10.1212/wnl.0000000000207923} } @article{erickson2011-21282661, author = {Erickson, K. I. and Voss, M. W. and Prakash, R. S. and Basak, C. and Szabo, A. and Chaddock, L. and Kim, J. S. and Heo, S. and others}, title = {{Exercise training increases size of hippocampus and improves memory}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2011}, doi = {10.1073/pnas.1015950108}, pmid = {21282661}, url = {https://doi.org/10.1073/pnas.1015950108} } @article{yaffe2004-15326238, author = {Yaffe, K. and Blackwell, T. and Kanaya, A. M. and Davidowitz, N. and Barrett-Connor, E. and Krueger, K.}, title = {{Diabetes, impaired fasting glucose, and development of cognitive impairment in older women}}, journal = {Neurology}, year = {2004}, doi = {10.1212/01.wnl.0000134666.64593.ba}, pmid = {15326238}, url = {https://doi.org/10.1212/01.wnl.0000134666.64593.ba} } @article{mirelman2016-27524393, author = {Mirelman, A. and Rochester, L. and Maidan, I. and Del Din, S. and Alcock, L. and Nieuwhof, F. and Rikkert, M. O. and Bloem, B. R. and others}, title = {{Addition of a non-immersive virtual reality component to treadmill training to reduce fall risk in older adults (V-TIME): a randomised controlled trial}}, journal = {Lancet (London, England)}, year = {2016}, doi = {10.1016/s0140-6736(16)31325-3}, pmid = {27524393}, url = {https://doi.org/10.1016/s0140-6736(16)31325-3} } @article{stephen2019-31164160, author = {Stephen, R. and Liu, Y. and Ngandu, T. and Antikainen, R. and Hulkkonen, J. and Koikkalainen, J. and Kemppainen, N. and Lötjönen, J. and others}, title = {{Brain volumes and cortical thickness on MRI in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)}}, journal = {Alzheimer's research \& therapy}, year = {2019}, doi = {10.1186/s13195-019-0506-z}, pmid = {31164160}, url = {https://doi.org/10.1186/s13195-019-0506-z} } @article{a2022-35150086, author = {Á, Casas-Herrero and Sáez de Asteasu, M. L. and Antón-Rodrigo, I. and Sánchez-Sánchez, J. L. and Montero-Odasso, M. and Marín-Epelde, I. and Ramón-Espinoza, F. and Zambom-Ferraresi, F. and others}, title = {{Effects of Vivifrail multicomponent intervention on functional capacity: a multicentre, randomized controlled trial}}, journal = {Journal of cachexia, sarcopenia and muscle}, year = {2022}, doi = {10.1002/jcsm.12925}, pmid = {35150086}, url = {https://doi.org/10.1002/jcsm.12925} } @article{fossey2006-16543297, author = {Fossey, J. and Ballard, C. and Juszczak, E. and James, I. and Alder, N. and Jacoby, R. and Howard, R.}, title = {{Effect of enhanced psychosocial care on antipsychotic use in nursing home residents with severe dementia: cluster randomised trial}}, journal = {BMJ (Clinical research ed.)}, year = {2006}, doi = {10.1136/bmj.38782.575868.7c}, pmid = {16543297}, url = {https://doi.org/10.1136/bmj.38782.575868.7c} } @article{oliveira2021-34065698, author = {Oliveira, Jorge and Gamito, Pedro and Souto, Teresa and Conde, Rita and Ferreira, Maria and Corotnean, Tatiana and Fernandes, Adriano and Silva, Henrique and others}, title = {{Virtual Reality-Based Cognitive Stimulation on People with Mild to Moderate Dementia due to Alzheimer's Disease: A Pilot Randomized Controlled Trial}}, journal = {International journal of environmental research and public health}, year = {2021}, doi = {10.3390/ijerph18105290}, pmid = {34065698}, url = {https://doi.org/10.3390/ijerph18105290} } @article{shyu2022-34036705, author = {Shyu, Yea-Ing L and Lin, Chung-Chih and Kwok, Yam-Ting and Shyu, Hann-Yeh and Kuo, Li-Min}, title = {{A community-based computerised cognitive training program for older persons with mild dementia: A pilot study}}, journal = {Australasian journal on ageing}, year = {2022}, doi = {10.1111/ajag.12962}, pmid = {34036705}, url = {https://doi.org/10.1111/ajag.12962} } @article{zuschnegg2025-40802794, author = {Zuschnegg, Julia and Ropele, Stefan and Opriessnig, Peter and Schmidt, Reinhold and Russegger, Silvia and Fellner, Maria and Leitner, Manuel and Spat, Stephan and others}, title = {{The effect of tablet-based multimodal training on cognitive functioning in Alzheimer's disease: A randomized controlled trial}}, journal = {PloS one}, year = {2025}, doi = {10.1371/journal.pone.0329931}, pmid = {40802794}, url = {https://doi.org/10.1371/journal.pone.0329931} } @article{ma2023-38298930, author = {Ma, Suk Ling and Tang, Katsie Tung and Lau, Niki Cheuk Ting and Chiu, Clement Lek Hin and Lin, Cuichan and Lam, Linda Chiu Wa and Lee, Allen Ting Chun}, title = {{Effect of computerized cognitive training on mood, cognition, and serum brain-derived neurotrophic factor level in late-life depression - a pilot randomized controlled trial}}, journal = {Frontiers in psychiatry}, year = {2023}, doi = {10.3389/fpsyt.2023.1287822}, pmid = {38298930}, url = {https://doi.org/10.3389/fpsyt.2023.1287822} } @article{inskip2016-27258533, author = {Inskip, Michael and Mavros, Yorgi and Sachdev, Perminder S and Singh, Maria A Fiatarone}, title = {{Exercise for Individuals with Lewy Body Dementia: A Systematic Review}}, journal = {PloS one}, year = {2016}, doi = {10.1371/journal.pone.0156520}, pmid = {27258533}, url = {https://doi.org/10.1371/journal.pone.0156520} } @article{baker2025-f1551689, author = {Baker, L. D. and others}, title = {{Structured vs Self-Guided Multidomain Lifestyle Interventions for Global Cognitive Function: The US POINTER Randomized Clinical Trial}}, journal = {JAMA}, year = {2025}, pmid = {40720610} } @article{reboussin2025-d972d843, author = {Reboussin, D. M. and Gaussoin, S. A. and Pajewski, N. M. and Jaeger, B. C. and Sachs, B. and Rapp, SR. and Supiano, M. A. and Cleveland, M. L. and Hunter, V. and Demons, J. L. and Ogrocki, P. K. and Lerner, A. J. and Chelune, G. J. and Wadley, V. G. and Scales, M. L. and Woolard, N. F. and Perdue, L. H. and Callahan, K. E. and Williamson, J. D.}, title = {{Long-Term Effect of Intensive vs Standard Blood Pressure Control on Mild Cognitive Impairment and Probable Dementia in SPRINT}}, journal = {Neurology}, year = {2025}, pmid = {39819096} } @article{feldman2010-20200346, author = {Feldman, H. H. and Doody, R. S. and Kivipelto, M. and Sparks, D. L. and Waters, D. D. and Jones, R. W. and Schwam, E. and Schindler, R. and others}, title = {{Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease: LEADe}}, journal = {Neurology}, year = {2010}, doi = {10.1212/wnl.0b013e3181d6476a}, pmid = {20200346}, url = {https://doi.org/10.1212/wnl.0b013e3181d6476a} } @article{adesuyan2024-38324745, author = {Adesuyan, M. and Jani, Y. H. and Alsugeir, D. and Howard, R. and Ju, C. and Wei, L. and Brauer, R.}, title = {{Phosphodiesterase Type 5 Inhibitors in Men With Erectile Dysfunction and the Risk of Alzheimer Disease: A Cohort Study}}, journal = {Neurology}, year = {2024}, doi = {10.1212/wnl.0000000000209131}, pmid = {38324745}, url = {https://doi.org/10.1212/wnl.0000000000209131} } @article{graff2006-17114212, author = {Graff, M. J. and Vernooij-Dassen, M. J. and Thijssen, M. and Dekker, J. and Hoefnagels, W. H. and Rikkert, M. G.}, title = {{Community based occupational therapy for patients with dementia and their care givers: randomised controlled trial}}, journal = {BMJ (Clinical research ed.)}, year = {2006}, doi = {10.1136/bmj.39001.688843.be}, pmid = {17114212}, url = {https://doi.org/10.1136/bmj.39001.688843.be} } @article{liu2021-33434704, author = {Liu, X. and Morris, M. C. and Dhana, K. and Ventrelle, J. and Johnson, K. and Bishop, L. and Hollings, C. S. and Boulin, A. and others}, title = {{Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) study: Rationale, design and baseline characteristics of a randomized control trial of the MIND diet on cognitive decline}}, journal = {Contemporary clinical trials}, year = {2021}, doi = {10.1016/j.cct.2021.106270}, pmid = {33434704}, url = {https://doi.org/10.1016/j.cct.2021.106270} } @article{kulmala2019-30809801, author = {Kulmala, J. and Ngandu, T. and Havulinna, S. and Levälahti, E. and Lehtisalo, J. and Solomon, A. and Antikainen, R. and Laatikainen, T. and others}, title = {{The Effect of Multidomain Lifestyle Intervention on Daily Functioning in Older People}}, journal = {Journal of the American Geriatrics Society}, year = {2019}, doi = {10.1111/jgs.15837}, pmid = {30809801}, url = {https://doi.org/10.1111/jgs.15837} } @article{bernini2021-32895890, author = {Bernini, S. and Panzarasa, S. and Barbieri, M. and Sinforiani, E. and Quaglini, S. and Tassorelli, C. and Bottiroli, S.}, title = {{A double-blind randomized controlled trial of the efficacy of cognitive training delivered using two different methods in mild cognitive impairment in Parkinson's disease: preliminary report of benefits associated with the use of a computerized tool}}, journal = {Aging clinical and experimental research}, year = {2021}, doi = {10.1007/s40520-020-01665-2}, pmid = {32895890}, url = {https://doi.org/10.1007/s40520-020-01665-2} } @article{rodella2022-34156651, author = {Rodella, C. and Bernini, S. and Panzarasa, S. and Sinforiani, E. and Picascia, M. and Quaglini, S. and Cavallini, E. and Vecchi, T. and others}, title = {{A double-blind randomized controlled trial combining cognitive training (CoRe) and neurostimulation (tDCS) in the early stages of cognitive impairment}}, journal = {Aging clinical and experimental research}, year = {2022}, doi = {10.1007/s40520-021-01912-0}, pmid = {34156651}, url = {https://doi.org/10.1007/s40520-021-01912-0} } @article{stephen2020-32925045, author = {Stephen, R. and Solomon, A. and Ngandu, T. and Levälahti, E. and Rinne, J. O. and Kemppainen, N. and Parkkola, R. and Antikainen, R. and others}, title = {{White Matter Changes on Diffusion Tensor Imaging in the FINGER Randomized Controlled Trial}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2020}, doi = {10.3233/jad-200423}, pmid = {32925045}, url = {https://doi.org/10.3233/jad-200423} } @article{kallio2018-29345724, author = {Kallio, E. L. and Öhman, H. and Hietanen, M. and Soini, H. and Strandberg, T. E. and Kautiainen, H. and Pitkälä, K. H.}, title = {{Effects of Cognitive Training on Cognition and Quality of Life of Older Persons with Dementia}}, journal = {Journal of the American Geriatrics Society}, year = {2018}, doi = {10.1111/jgs.15196}, pmid = {29345724}, url = {https://doi.org/10.1111/jgs.15196} } @article{beishuizen2017-28263374, author = {Beishuizen, C. R. L. and Coley, N. and Moll van Charante, E. P. and van Gool, W. A. and Richard, E. and Andrieu, S.}, title = {{Determinants of Dropout and Nonadherence in a Dementia Prevention Randomized Controlled Trial: The Prevention of Dementia by Intensive Vascular Care Trial}}, journal = {Journal of the American Geriatrics Society}, year = {2017}, doi = {10.1111/jgs.14834}, pmid = {28263374}, url = {https://doi.org/10.1111/jgs.14834} } @article{morris2017-28187125, author = {Morris, J. K. and Vidoni, E. D. and Johnson, D. K. and Van Sciver, A. and Mahnken, J. D. and Honea, R. A. and Wilkins, H. M. and Brooks, W. M. and others}, title = {{Aerobic exercise for Alzheimer's disease: A randomized controlled pilot trial}}, journal = {PloS one}, year = {2017}, doi = {10.1371/journal.pone.0170547}, pmid = {28187125}, url = {https://doi.org/10.1371/journal.pone.0170547} } @article{sampson2007-17006875, author = {Sampson, E. L. and Raven, P. R. and Ndhlovu, P. N. and Vallance, A. and Garlick, N. and Watts, J. and Blanchard, M. R. and Bruce, A. and others}, title = {{A randomized, double-blind, placebo-controlled trial of donepezil hydrochloride (Aricept) for reducing the incidence of postoperative delirium after elective total hip replacement}}, journal = {International journal of geriatric psychiatry}, year = {2007}, doi = {10.1002/gps.1679}, pmid = {17006875}, url = {https://doi.org/10.1002/gps.1679} } @article{vandenboogaard2013-23327295, author = {van den Boogaard, M. and Schoonhoven, L. and van Achterberg, T. and van der Hoeven, J. G. and Pickkers, P.}, title = {{Haloperidol prophylaxis in critically ill patients with a high risk for delirium}}, journal = {Critical care (London, England)}, year = {2013}, doi = {10.1186/cc11933}, pmid = {23327295}, url = {https://doi.org/10.1186/cc11933} } @article{bonner2021-32308012, author = {Bonner, G. J. and Freels, S. and Ferrans, C. and Steffen, A. and Suarez, M. L. and Dancy, B. L. and Watkins, Y. J. and Collinge, W. and others}, title = {{Advance Care Planning for African American Caregivers of Relatives With Dementias: Cluster Randomized Controlled Trial}}, journal = {The American journal of hospice \& palliative care}, year = {2021}, doi = {10.1177/1049909120916127}, pmid = {32308012}, url = {https://doi.org/10.1177/1049909120916127} } @article{triana2020-32429770, author = {Triana, Austin J. and Gusdorf, Roman E and Shah, Kaustav P. and Horst, Sara}, title = {{Technology Literacy as a Barrier to Telehealth During COVID-19}}, journal = {Telemedicine Journal and e-Health}, year = {2020}, doi = {10.1089/tmj.2020.0155}, pmid = {32429770}, url = {https://doi.org/10.1089/tmj.2020.0155} } @article{hart2007-17938402, author = {Hart, Robert G. and Pearce, Lesly A. and Aguilar, Maria I.}, title = {{Adjusted-Dose Warfarin versus Aspirin for Preventing Stroke in Patients with Atrial Fibrillation}}, journal = {Annals of Internal Medicine}, year = {2007}, doi = {10.7326/0003-4819-147-8-200710160-00018}, pmid = {17938402}, url = {https://doi.org/10.7326/0003-4819-147-8-200710160-00018} } @article{tolosa2014-24532007, author = {TOLOSA, EDUARDO S. and Litvan, Irene and Höglinger, Günter U. and Burn, David John and Lees, Andrew John and de Andrés, Maria Velasco and Gómez‐Carrillo, Belén and León, Teresa and others}, title = {{A phase 2 trial of the GSK‐3 inhibitor tideglusib in progressive supranuclear palsy}}, journal = {Movement Disorders}, year = {2014}, doi = {10.1002/mds.25824}, pmid = {24532007}, url = {https://doi.org/10.1002/mds.25824} } @article{teri2003-14559955, author = {Teri, L. and Gibbons, L. E. and McCurry, S. M. and Logsdon, R. G. and Buchner, D. M. and Barlow, W. E. and Kukull, W. A. and LaCroix, A. Z. and others}, title = {{Exercise plus behavioral management in patients with Alzheimer disease: a randomized controlled trial}}, journal = {JAMA}, year = {2003}, doi = {10.1001/jama.290.15.2015}, pmid = {14559955}, url = {https://doi.org/10.1001/jama.290.15.2015} } @article{lannfelt2008-18672400, author = {Lannfelt, L. and Blennow, K. and Zetterberg, H. and Batsman, S. and Ames, D. and Harrison, J. and Masters, C. L. and Targum, S. and others}, title = {{Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial}}, journal = {The Lancet. Neurology}, year = {2008}, doi = {10.1016/s1474-4422(08)70167-4}, pmid = {18672400}, url = {https://doi.org/10.1016/s1474-4422(08)70167-4} } @article{tomoto2022-34570024, author = {Tomoto, Tsubasa and Le, Tran and Tarumi, Takashi and Dieppa, Marisara and Bell, Kathleen and Madden, Christopher and Zhang, Rong and Ding, Kan}, title = {{Carotid Arterial Compliance and Aerobic Exercise Training in Chronic Traumatic Brain Injury: A Pilot Study}}, journal = {The Journal of head trauma rehabilitation}, year = {2022}, doi = {10.1097/htr.0000000000000722}, pmid = {34570024}, url = {https://doi.org/10.1097/htr.0000000000000722} } @article{shrestha2022-33357171, author = {Shrestha, Srijana and Richey, Sheila and Lipovac-Dew, Martha and Kunik, Mark E and Stanley, Melinda A and Ramsey, David and Amspoker, Amber B}, title = {{An Examination of Positive and Negative Dementia Caregiving Experiences}}, journal = {Clinical gerontologist}, year = {2022}, doi = {10.1080/07317115.2020.1868033}, pmid = {33357171}, url = {https://doi.org/10.1080/07317115.2020.1868033} } @article{fuju2022-34951029, author = {Fuju, Taiga and Yamagami, Tetsuya and Yamaguchi, Haruyasu and Yamazaki, Tsuneo}, title = {{A randomized controlled trial of the "positive diary" intervention for family caregivers of people with dementia}}, journal = {Perspectives in psychiatric care}, year = {2022}, doi = {10.1111/ppc.13013}, pmid = {34951029}, url = {https://doi.org/10.1111/ppc.13013} } @article{wu2020-30795711, author = {Wu, Chiu-Hsiang Chiu and Perng, Shoa-Jen and Shi, Chun-Kuan and Lai, Hui-Ling}, title = {{Advance Care Planning and Advance Directives: A Multimedia Education Program in Community-Dwelling Older Adults}}, journal = {Journal of applied gerontology : the official journal of the Southern Gerontological Society}, year = {2020}, doi = {10.1177/0733464819831596}, pmid = {30795711}, url = {https://doi.org/10.1177/0733464819831596} } @article{ngandu2015-18edebfe, author = {Ngandu, T. and Lehtisalo, J. and Solomon, A. and Levälahti, E. and Ahtiluoto, S. and Antikainen, R. and Bäckman, L. and Hänninen, T. and Jula, A. and Laatikainen, T. and Lindström, J. and Mangialasche, F. and Paajanen, T. and Pajala, S. and Peltonen, M. and Rauramaa, R. and Stigsdotter-Neely, A. and Strandberg, T. and Tuomilehto, J. and Soininen, H. and Kivipelto, M.}, title = {{A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial}}, journal = {The Lancet}, year = {2015}, doi = {10.1016/s0140-6736(15)60461-5}, pmid = {25771249}, url = {https://doi.org/10.1016/s0140-6736(15)60461-5} } @article{aisen2011-22291741, author = {Aisen, P. S. and Gauthier, S. and Ferris, S. H. and Saumier, D. and Haine, D. and Garceau, D. and Duong, A. and Suhy, J. and others}, title = {{Tramiprosate in mild-to-moderate Alzheimer's disease - a randomized, double-blind, placebo-controlled, multi-centre study (the Alphase Study)}}, journal = {Archives of medical science : AMS}, year = {2011}, doi = {10.5114/aoms.2011.20612}, pmid = {22291741}, url = {https://doi.org/10.5114/aoms.2011.20612} } @article{coric2015-26414022, author = {Coric, V. and Salloway, S. and van Dyck, C. H. and Dubois, B. and Andreasen, N. and Brody, M. and Curtis, C. and Soininen, H. and others}, title = {{Targeting Prodromal Alzheimer Disease With Avagacestat: A Randomized Clinical Trial}}, journal = {JAMA neurology}, year = {2015}, doi = {10.1001/jamaneurol.2015.0607}, pmid = {26414022}, url = {https://doi.org/10.1001/jamaneurol.2015.0607} } @article{martinezlapiscina2013-23732551, author = {Martínez-Lapiscina, E. H. and Clavero, P. and Toledo, E. and San Julián, B. and Sanchez-Tainta, A. and Corella, D. and Lamuela-Raventós, R. M. and Martínez, J. A. and others}, title = {{Virgin olive oil supplementation and long-term cognition: the PREDIMED-NAVARRA randomized, trial}}, journal = {The journal of nutrition, health \& aging}, year = {2013}, doi = {10.1007/s12603-013-0027-6}, pmid = {23732551}, url = {https://doi.org/10.1007/s12603-013-0027-6} } @article{marcantonio2001-11380742, author = {Marcantonio, E. R. and Flacker, J. M. and Wright, R. J. and Resnick, N. M.}, title = {{Reducing delirium after hip fracture: a randomized trial}}, journal = {Journal of the American Geriatrics Society}, year = {2001}, doi = {10.1046/j.1532-5415.2001.49108.x}, pmid = {11380742}, url = {https://doi.org/10.1046/j.1532-5415.2001.49108.x} } @article{mcmaster2020-32909259, author = {McMaster, M. and Kim, S. and Clare, L. and Torres, S. J. and Cherbuin, N. and DʼEste, C. and Anstey, K. J.}, title = {{Lifestyle Risk Factors and Cognitive Outcomes from the Multidomain Dementia Risk Reduction Randomized Controlled Trial, Body Brain Life for Cognitive Decline (BBL-CD)}}, journal = {Journal of the American Geriatrics Society}, year = {2020}, doi = {10.1111/jgs.16762}, pmid = {32909259}, url = {https://doi.org/10.1111/jgs.16762} } @article{tenbrinke2018-29378515, author = {Ten Brinke, L. F. and Best, JR. and Crockett, R. A. and Liu-Ambrose, T.}, title = {{The effects of an 8-week computerized cognitive training program in older adults: a study protocol for a randomized controlled trial}}, journal = {BMC geriatrics}, year = {2018}, doi = {10.1186/s12877-018-0730-6}, pmid = {29378515}, url = {https://doi.org/10.1186/s12877-018-0730-6} } @article{xu2020-33194354, author = {Xu, Z. and Zhang, D. and Lee, A. T. C. and Sit, R. W. S. and Wong, C. and Lee, E. K. P. and Yip, B. H. K. and Tiu, J. Y. S. and others}, title = {{A pilot feasibility randomized controlled trial on combining mind-body physical exercise, cognitive training, and nurse-led risk factor modification to reduce cognitive decline among older adults with mild cognitive impairment in primary care}}, journal = {PeerJ}, year = {2020}, doi = {10.7717/peerj.9845}, pmid = {33194354}, url = {https://doi.org/10.7717/peerj.9845} } @article{sieber2010-20042557, author = {Sieber, F. E. and Zakriya, K. J. and Gottschalk, A. and Blute, M. R. and Lee, H. B. and Rosenberg, P. B. and Mears, S. C.}, title = {{Sedation depth during spinal anesthesia and the development of postoperative delirium in elderly patients undergoing hip fracture repair}}, journal = {Mayo Clinic proceedings}, year = {2010}, doi = {10.4065/mcp.2009.0469}, pmid = {20042557}, url = {https://doi.org/10.4065/mcp.2009.0469} } @article{agar2017-28786995, author = {Agar, M. and Luckett, T. and Luscombe, G. and Phillips, J. and Beattie, E. and Pond, D. and Mitchell, G. and Davidson, P. M. and others}, title = {{Effects of facilitated family case conferencing for advanced dementia: A cluster randomised clinical trial}}, journal = {PloS one}, year = {2017}, doi = {10.1371/journal.pone.0181020}, pmid = {28786995}, url = {https://doi.org/10.1371/journal.pone.0181020} } @article{mor2017-28068789, author = {Mor, V. and Volandes, A. E. and Gutman, R. and Gatsonis, C. and Mitchell, S. L.}, title = {{PRagmatic trial Of Video Education in Nursing homes: The design and rationale for a pragmatic cluster randomized trial in the nursing home setting}}, journal = {Clinical trials (London, England)}, year = {2017}, doi = {10.1177/1740774516685298}, pmid = {28068789}, url = {https://doi.org/10.1177/1740774516685298} } @article{sampson2008-18620567, author = {Sampson, E. L. and Thuné-Boyle, I. and Kukkastenvehmas, R. and Jones, L. and Tookman, A. and King, M. and Blanchard, M. R.}, title = {{Palliative care in advanced dementia; A mixed methods approach for the development of a complex intervention}}, journal = {BMC palliative care}, year = {2008}, doi = {10.1186/1472-684x-7-8}, pmid = {18620567}, url = {https://doi.org/10.1186/1472-684x-7-8} } @article{vanelderen2010-20837967, author = {van Elderen, S. G. and de Roos, A. and de Craen, A. J. and Westendorp, R. G. and Blauw, G. J. and Jukema, J. W. and Bollen, E. L. and Middelkoop, H. A. and others}, title = {{Progression of brain atrophy and cognitive decline in diabetes mellitus: a 3-year follow-up}}, journal = {Neurology}, year = {2010}, doi = {10.1212/wnl.0b013e3181f25f06}, pmid = {20837967}, url = {https://doi.org/10.1212/wnl.0b013e3181f25f06} } @article{meltzer2023-34694201, author = {Meltzer, J. A. and Kates Rose, M. and Le, A. Y. and Spencer, K. A. and Goldstein, L. and Gubanova, A. and Lai, A. C. and Yossofzai, M. and others}, title = {{Improvement in executive function for older adults through smartphone apps: a randomized clinical trial comparing language learning and brain training}}, journal = {Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition}, year = {2023}, doi = {10.1080/13825585.2021.1991262}, pmid = {34694201}, url = {https://doi.org/10.1080/13825585.2021.1991262} } @article{weaver2012-22722632, author = {Weaver, F. M. and Follett, K. A. and Stern, M. and Luo, P. and Harris, C. L. and Hur, K. and Marks, W. J. and Rothlind, J. and others}, title = {{Randomized trial of deep brain stimulation for Parkinson disease: thirty-six-month outcomes}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e31825dcdc1}, pmid = {22722632}, url = {https://doi.org/10.1212/wnl.0b013e31825dcdc1} } @article{lin2023-4ecff333, author = {Lin, F. R. and Pike, JR. and Albert, M. S. and others}, title = {{Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial}}, journal = {The Lancet}, year = {2023}, pmid = {37478886} } @article{study2026-c3d280c0, title = {{The glymphatic system clears amyloid beta and tau from brain to plasma in humans}}, journal = {Nature Communications}, year = {2026} } @article{mittelman2006-b972b154, author = {Mittelman, M. S. and Haley, W. E. and Clay, O. J. and Roth, D. L.}, title = {{Improving Caregiver Well-Being Delays Nursing Home Placement of Patients With Alzheimer Disease}}, journal = {Neurology}, year = {2006}, pmid = {17101889} } @article{mittelman2006-17101889, author = {Mittelman, M. S. and Haley, W. E. and Clay, O. J. and Roth, D. L.}, title = {{Improving caregiver well-being delays nursing home placement of patients with Alzheimer disease}}, journal = {Neurology}, year = {2006}, doi = {10.1212/01.wnl.0000242727.81172.91}, pmid = {17101889}, url = {https://doi.org/10.1212/01.wnl.0000242727.81172.91} } @article{pitkala2013-23589097, author = {Pitkälä, K. H. and Pöysti, M. M. and Laakkonen, M. L. and Tilvis, R. S. and Savikko, N. and Kautiainen, H. and Strandberg, T. E.}, title = {{Effects of the Finnish Alzheimer disease exercise trial (FINALEX): a randomized controlled trial}}, journal = {JAMA internal medicine}, year = {2013}, doi = {10.1001/jamainternmed.2013.359}, pmid = {23589097}, url = {https://doi.org/10.1001/jamainternmed.2013.359} } @article{spector2003-12948999, author = {Spector, A. and Thorgrimsen, L. and Woods, B. and Royan, L. and Davies, S. and Butterworth, M. and Orrell, M.}, title = {{Efficacy of an evidence-based cognitive stimulation therapy programme for people with dementia: randomised controlled trial}}, journal = {The British journal of psychiatry : the journal of mental science}, year = {2003}, doi = {10.1192/bjp.183.3.248}, pmid = {12948999}, url = {https://doi.org/10.1192/bjp.183.3.248} } @article{anderson2011-20980201, author = {Anderson, C. and Teo, K. and Gao, P. and Arima, H. and Dans, A. and Unger, T. and Commerford, P. and Dyal, L. and others}, title = {{Renin-angiotensin system blockade and cognitive function in patients at high risk of cardiovascular disease: analysis of data from the ONTARGET and TRANSCEND studies}}, journal = {The Lancet. Neurology}, year = {2011}, doi = {10.1016/s1474-4422(10)70250-7}, pmid = {20980201}, url = {https://doi.org/10.1016/s1474-4422(10)70250-7} } @article{hwang2020-31479083, author = {Hwang, Hei-Fen and Chen, Chih-Yi and Wei, Li and Chen, Sy-Jou and Yu, Wen-Yu and Lin, Mau-Roung}, title = {{Effects of Computerized Cognitive Training and Tai Chi on Cognitive Performance in Older Adults With Traumatic Brain Injury}}, journal = {The Journal of head trauma rehabilitation}, year = {2020}, doi = {10.1097/htr.0000000000000533}, pmid = {31479083}, url = {https://doi.org/10.1097/htr.0000000000000533} } @article{rapaport2024-39366393, author = {Rapaport, P. and Amador, S. and Adeleke, M. O. and Barber, J. A. and Banerjee, S. and Charlesworth, G. and others}, title = {{Clinical effectiveness of DREAMS START (Dementia Related Manual for Sleep; Strategies for Relatives) versus usual care for people with dementia and their carers: a single-masked, phase 3, parallel-arm, superiority randomised controlled trial}}, journal = {The Lancet Healthy Longevity}, year = {2024}, doi = {10.1016/j.lanhl.2024.08.004}, pmid = {39366393}, url = {https://doi.org/10.1016/j.lanhl.2024.08.004} } @article{crivelli2026-42442374, author = {Crivelli, L. and Suemoto, C. K. and Sosa, A. L. and Lopera, F. and Aguillón, D. and Allegri, R. F. and Nitrini, R. and Calandri, I. L. and Velilla-Jiménez, L. and Yassuda, M. S. and others}, title = {{Multidomain lifestyle intervention for the prevention of cognitive decline in at-risk older adults in Latin America (LatAm-FINGERS): a single-blind, multicentre, randomised controlled trial}}, journal = {The Lancet}, year = {2026}, doi = {10.1016/S0140-6736(26)01278-X}, pmid = {42442374}, url = {https://doi.org/10.1016/S0140-6736(26)01278-X} } @article{gitlin2010-20810376, author = {Gitlin, L. N. and Winter, L. and Dennis, M. P. and Hodgson, N. and Hauck, W. W.}, title = {{A biobehavioral home-based intervention and the well-being of patients with dementia and their caregivers: the COPE randomized trial}}, journal = {JAMA}, year = {2010}, doi = {10.1001/jama.2010.1253}, pmid = {20810376}, url = {https://doi.org/10.1001/jama.2010.1253} } @article{yu2021-33523004, author = {Yu, F. and Vock, D. M. and Zhang, L. and Salisbury, D. and Nelson, N. W. and Chow, L. S. and Smith, G. and Barclay, T. R. and others}, title = {{Cognitive Effects of Aerobic Exercise in Alzheimer's Disease: A Pilot Randomized Controlled Trial}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2021}, doi = {10.3233/jad-201100}, pmid = {33523004}, url = {https://doi.org/10.3233/jad-201100} } @article{clare2019-30724405, author = {Clare, L. and Kudlicka, A. and Oyebode, JR. and Jones, R. W. and Bayer, A. and Leroi, I. and Kopelman, M. and James, I. A. and others}, title = {{Individual goal-oriented cognitive rehabilitation to improve everyday functioning for people with early-stage dementia: A multicentre randomised controlled trial (the GREAT trial)}}, journal = {International journal of geriatric psychiatry}, year = {2019}, doi = {10.1002/gps.5076}, pmid = {30724405}, url = {https://doi.org/10.1002/gps.5076} } @article{temba2025-40181181, author = {Temba, Godfrey S. and Pecht, Tal and Kullaya, Vesla I. and Vadaq, Nadira and Mosha, Mary and Ulas, Thomas and Kanungo, Sneha and van Emst, Liesbeth and others}, title = {{Immune and metabolic effects of African heritage diets versus Western diets in men: a randomized controlled trial}}, journal = {Nature Medicine}, year = {2025}, doi = {10.1038/s41591-025-03602-0}, pmid = {40181181}, url = {https://doi.org/10.1038/s41591-025-03602-0} } @article{coe2026-41669119, author = {Coe, Norma B. and Miller, Katherine E. M. and Sun, Chuxuan and Taggert, Elizabeth and Gross, Alden L. and Jones, Richard Norman and Felix, Cynthia and Albert, Marilyn S. and others}, title = {{Impact of cognitive training on claims‐based diagnosed dementia over 20 years: evidence from the ACTIVE study}}, journal = {Alzheimer s \& Dementia Translational Research \& Clinical Interventions}, year = {2026}, doi = {10.1002/trc2.70197}, pmid = {41669119}, url = {https://doi.org/10.1002/trc2.70197} } @article{martinezlapiscina2014-24643340, author = {Martínez-Lapiscina, E. H. and Galbete, C. and Corella, D. and Toledo, E. and Buil-Cosiales, P. and Salas-Salvado, J. and Ros, E. and Martinez-Gonzalez, M. A.}, title = {{Genotype patterns at CLU, CR1, PICALM and APOE, cognition and Mediterranean diet: the PREDIMED-NAVARRA trial}}, journal = {Genes \& nutrition}, year = {2014}, doi = {10.1007/s12263-014-0393-7}, pmid = {24643340}, url = {https://doi.org/10.1007/s12263-014-0393-7} } @article{petrelli2015-25534579, author = {Petrelli, A. and Kaesberg, S. and Barbe, M. T. and Timmermann, L. and Rosen, J. B. and Fink, G. R. and Kessler, J. and Kalbe, E.}, title = {{Cognitive training in Parkinson's disease reduces cognitive decline in the long term}}, journal = {European journal of neurology}, year = {2015}, doi = {10.1111/ene.12621}, pmid = {25534579}, url = {https://doi.org/10.1111/ene.12621} } @article{yeh2019-30639273, author = {Yeh, T. T. and Chang, K. C. and Wu, C. Y.}, title = {{The Active Ingredient of Cognitive Restoration: A Multicenter Randomized Controlled Trial of Sequential Combination of Aerobic Exercise and Computer-Based Cognitive Training in Stroke Survivors With Cognitive Decline}}, journal = {Archives of physical medicine and rehabilitation}, year = {2019}, doi = {10.1016/j.apmr.2018.12.020}, pmid = {30639273}, url = {https://doi.org/10.1016/j.apmr.2018.12.020} } @article{gill2016-26285025, author = {Gill, D. P. and Gregory, M. A. and Zou, G. and Liu-Ambrose, T. and Shigematsu, R. and Hachinski, V. and Fitzgerald, C. and Petrella, R. J.}, title = {{The Healthy Mind, Healthy Mobility Trial: A Novel Exercise Program for Older Adults}}, journal = {Medicine and science in sports and exercise}, year = {2016}, doi = {10.1249/mss.0000000000000758}, pmid = {26285025}, url = {https://doi.org/10.1249/mss.0000000000000758} } @article{bergamaschi2013-23784727, author = {Bergamaschi, S. and Arcara, G. and Calza, A. and Villani, D. and Orgeta, V. and Mondini, S.}, title = {{One-year repeated cycles of cognitive training (CT) for Alzheimer's disease}}, journal = {Aging clinical and experimental research}, year = {2013}, doi = {10.1007/s40520-013-0065-2}, pmid = {23784727}, url = {https://doi.org/10.1007/s40520-013-0065-2} } @article{chenoweth2009-19282246, author = {Chenoweth, L. and King, M. T. and Jeon, Y. H. and Brodaty, H. and Stein-Parbury, J. and Norman, R. and Haas, M. and Luscombe, G.}, title = {{Caring for Aged Dementia Care Resident Study (CADRES) of person-centred care, dementia-care mapping, and usual care in dementia: a cluster-randomised trial}}, journal = {The Lancet. Neurology}, year = {2009}, doi = {10.1016/s1474-4422(09)70045-6}, pmid = {19282246}, url = {https://doi.org/10.1016/s1474-4422(09)70045-6} } @article{shaw2003-12521968, author = {Shaw, F. E. and Bond, J. and Richardson, D. A. and Dawson, P. and Steen, I. N. and McKeith, I. G. and Kenny, R. A.}, title = {{Multifactorial intervention after a fall in older people with cognitive impairment and dementia presenting to the accident and emergency department: randomised controlled trial}}, journal = {BMJ (Clinical research ed.)}, year = {2003}, doi = {10.1136/bmj.326.7380.73}, pmid = {12521968}, url = {https://doi.org/10.1136/bmj.326.7380.73} } @article{saltvedt2002-12028163, author = {Saltvedt, I. and Mo, E. S. and Fayers, P. and Kaasa, S. and Sletvold, O.}, title = {{Reduced mortality in treating acutely sick, frail older patients in a geriatric evaluation and management unit. A prospective randomized trial}}, journal = {Journal of the American Geriatrics Society}, year = {2002}, doi = {10.1046/j.1532-5415.2002.50202.x}, pmid = {12028163}, url = {https://doi.org/10.1046/j.1532-5415.2002.50202.x} } @article{galik2014-24092822, author = {Galik, E. and Resnick, B. and Hammersla, M. and Brightwater, J.}, title = {{Optimizing function and physical activity among nursing home residents with dementia: testing the impact of function-focused care}}, journal = {The Gerontologist}, year = {2014}, doi = {10.1093/geront/gnt108}, pmid = {24092822}, url = {https://doi.org/10.1093/geront/gnt108} } @article{brazil2018-28786323, author = {Brazil, K. and Carter, G. and Cardwell, C. and Clarke, M. and Hudson, P. and Froggatt, K. and McLaughlin, D. and Passmore, P. and others}, title = {{Effectiveness of advance care planning with family carers in dementia nursing homes: A paired cluster randomized controlled trial}}, journal = {Palliative medicine}, year = {2018}, doi = {10.1177/0269216317722413}, pmid = {28786323}, url = {https://doi.org/10.1177/0269216317722413} } @article{hanson2019-30342242, author = {Hanson, L. C. and Kistler, C. E. and Lavin, K. and Gabriel, S. L. and Ernecoff, N. C. and Lin, F. C. and Sachs, G. A. and Mitchell, S. L.}, title = {{Triggered Palliative Care for Late-Stage Dementia: A Pilot Randomized Trial}}, journal = {Journal of pain and symptom management}, year = {2019}, doi = {10.1016/j.jpainsymman.2018.10.494}, pmid = {30342242}, url = {https://doi.org/10.1016/j.jpainsymman.2018.10.494} } @article{hanson2016-27271683, author = {Hanson, L. C. and Song, M. K. and Zimmerman, S. and Gilliam, R. and Rosemond, C. and Chisholm, L. and Lin, F. C.}, title = {{Fidelity to a behavioral intervention to improve goals of care decisions for nursing home residents with advanced dementia}}, journal = {Clinical trials (London, England)}, year = {2016}, doi = {10.1177/1740774516650863}, pmid = {27271683}, url = {https://doi.org/10.1177/1740774516650863} } @article{avilesolmos2014-24662192, author = {Aviles-Olmos, I. and Dickson, J. and Kefalopoulou, Z. and Djamshidian, A. and Kahan, J. and Ell, P. and Whitton, P. and Wyse, R. and others}, title = {{Motor and cognitive advantages persist 12 months after exenatide exposure in Parkinson's disease}}, journal = {Journal of Parkinson's disease}, year = {2014}, doi = {10.3233/jpd-140364}, pmid = {24662192}, url = {https://doi.org/10.3233/jpd-140364} } @article{hock2003-12765607, author = {Hock, C. and Konietzko, U. and Streffer, JR. and Tracy, J. and Signorell, A. and Müller-Tillmanns, B. and Lemke, U. and Henke, K. and others}, title = {{Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease}}, journal = {Neuron}, year = {2003}, doi = {10.1016/s0896-6273(03)00294-0}, pmid = {12765607}, url = {https://doi.org/10.1016/s0896-6273(03)00294-0} } @article{hoffmann2016-26682695, author = {Hoffmann, K. and Sobol, N. A. and Frederiksen, K. S. and Beyer, N. and Vogel, A. and Vestergaard, K. and Brændgaard, H. and Gottrup, H. and others}, title = {{Moderate-to-High Intensity Physical Exercise in Patients with Alzheimer's Disease: A Randomized Controlled Trial}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2016}, doi = {10.3233/jad-150817}, pmid = {26682695}, url = {https://doi.org/10.3233/jad-150817} } @article{deal2018-30364572, author = {Deal, J. A. and Goman, A. M. and Albert, M. S. and Arnold, M. L. and Burgard, S. and Chisolm, T. and Couper, D. and Glynn, N. W. and others}, title = {{Hearing treatment for reducing cognitive decline: Design and methods of the Aging and Cognitive Health Evaluation in Elders randomized controlled trial}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2018}, doi = {10.1016/j.trci.2018.08.007}, pmid = {30364572}, url = {https://doi.org/10.1016/j.trci.2018.08.007} } @article{study2006-46801c00, author = {{REACH II Investigators}}, title = {{Enhancing the Quality of Life of Dementia Caregivers From Different Ethnic or Racial Groups: A Randomized, Controlled Trial}}, journal = {Annals of Internal Medicine}, year = {2006}, doi = {10.7326/0003-4819-145-10-200611210-00005}, pmid = {17116917}, url = {https://doi.org/10.7326/0003-4819-145-10-200611210-00005} } @article{michalowsky2024-38967926, author = {Michalowsky, B. and Blotenberg, I. and Platen, M. and Teipel, S. and Kilimann, I. and Portacolone, E. and Bohlken, J. and Rädke, A. and Buchholz, M. and Scharf, A. and Muehlichen, F. and Xie, F. and others}, title = {{Clinical Outcomes and Cost-Effectiveness of Collaborative Dementia Care: A Secondary Analysis of a Cluster Randomized Clinical Trial}}, journal = {JAMA Network Open}, year = {2024}, doi = {10.1001/jamanetworkopen.2024.19282}, pmid = {38967926}, url = {https://doi.org/10.1001/jamanetworkopen.2024.19282} } @article{belleville2022-35049127, author = {Belleville, S. and Cloutier, S. and Mellah, S. and Willis, S. and Vellas, B. and Andrieu, S. and Coley, N. and Ngandu, T. and others}, title = {{Is more always better? Dose effect in a multidomain intervention in older adults at risk of dementia}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2022}, doi = {10.1002/alz.12544}, pmid = {35049127}, url = {https://doi.org/10.1002/alz.12544} } @article{riemersmavanderlek2008-18544724, author = {Riemersma-van der Lek, R. F. and Swaab, D. F. and Twisk, J. and Hol, E. M. and Hoogendijk, W. J. and Van Someren, E. J.}, title = {{Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial}}, journal = {JAMA}, year = {2008}, doi = {10.1001/jama.299.22.2642}, pmid = {18544724}, url = {https://doi.org/10.1001/jama.299.22.2642} } @article{cristancholacroix2015-25967983, author = {Cristancho-Lacroix, V. and Wrobel, J. and Cantegreil-Kallen, I. and Dub, T. and Rouquette, A. and Rigaud, A. S.}, title = {{A web-based psychoeducational program for informal caregivers of patients with Alzheimer's disease: a pilot randomized controlled trial}}, journal = {Journal of medical Internet research}, year = {2015}, doi = {10.2196/jmir.3717}, pmid = {25967983}, url = {https://doi.org/10.2196/jmir.3717} } @article{dias2008-18523642, author = {Dias, A. and Dewey, M. E. and D'Souza, J. and Dhume, R. and Motghare, D. D. and Shaji, K. S. and Menon, R. and Prince, M. and others}, title = {{The effectiveness of a home care program for supporting caregivers of persons with dementia in developing countries: a randomised controlled trial from Goa, India}}, journal = {PloS one}, year = {2008}, doi = {10.1371/journal.pone.0002333}, pmid = {18523642}, url = {https://doi.org/10.1371/journal.pone.0002333} } @article{seppi2011-22021174, author = {Seppi, K. and Weintraub, D. and Coelho, M. and Perez-Lloret, S. and Fox, S. H. and Katzenschlager, R. and Hametner, E. M. and Poewe, W. and others}, title = {{The Movement Disorder Society Evidence-Based Medicine Review Update: Treatments for the non-motor symptoms of Parkinson's disease}}, journal = {Movement disorders : official journal of the Movement Disorder Society}, year = {2011}, doi = {10.1002/mds.23884}, pmid = {22021174}, url = {https://doi.org/10.1002/mds.23884} } @article{orrell2017-28350796, author = {Orrell, M. and Yates, L. and Leung, P. and Kang, S. and Hoare, Z. and Whitaker, C. and Burns, A. and others}, title = {{The impact of individual Cognitive Stimulation Therapy (iCST) on cognition, quality of life, caregiver health, and family relationships in dementia: A randomised controlled trial}}, journal = {PLoS medicine}, year = {2017}, doi = {10.1371/journal.pmed.1002269}, pmid = {28350796}, url = {https://doi.org/10.1371/journal.pmed.1002269} } @article{smithray2014-25274713, author = {Smith-Ray, R. L. and Makowski-Woidan, B. and Hughes, S. L.}, title = {{A randomized trial to measure the impact of a community-based cognitive training intervention on balance and gait in cognitively intact Black older adults}}, journal = {Health education \& behavior : the official publication of the Society for Public Health Education}, year = {2014}, doi = {10.1177/1090198114537068}, pmid = {25274713}, url = {https://doi.org/10.1177/1090198114537068} } @article{hassandra2021-33759797, author = {Hassandra, M. and Galanis, E. and Hatzigeorgiadis, A. and Goudas, M. and Mouzakidis, C. and Karathanasi, E. M. and Petridou, N. and Tsolaki, M. and others}, title = {{Α Virtual Reality App for Physical and Cognitive Training of Older People With Mild Cognitive Impairment: Mixed Methods Feasibility Study}}, journal = {JMIR serious games}, year = {2021}, doi = {10.2196/24170}, pmid = {33759797}, url = {https://doi.org/10.2196/24170} } @article{sugimoto2021-34585222, author = {Sugimoto, T. and Sakurai, T. and Akatsu, H. and Doi, T. and Fujiwara, Y. and Hirakawa, A. and Kinoshita, F. and Kuzuya, M. and others}, title = {{The Japan-Multimodal Intervention Trial for Prevention of Dementia (J-MINT): The Study Protocol for an 18-Month, Multicenter, Randomized, Controlled Trial}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2021}, doi = {10.14283/jpad.2021.29}, pmid = {34585222}, url = {https://doi.org/10.14283/jpad.2021.29} } @article{quinn2021-34746430, author = {Quinn, T. J. and Richard, E. and Teuschl, Y. and Gattringer, T. and Hafdi, M. and O'Brien, J. T. and Merriman, N. and Gillebert, C. and others}, title = {{European Stroke Organisation and European Academy of Neurology joint guidelines on post-stroke cognitive impairment}}, journal = {European stroke journal}, year = {2021}, doi = {10.1177/23969873211042192}, pmid = {34746430}, url = {https://doi.org/10.1177/23969873211042192} } @article{ahronheim2000-15859668, author = {Ahronheim, J. C. and Morrison, R. S. and Morris, J. and Baskin, S. and Meier, D. E.}, title = {{Palliative care in advanced dementia: a randomized controlled trial and descriptive analysis}}, journal = {Journal of palliative medicine}, year = {2000}, doi = {10.1089/jpm.2000.3.265}, pmid = {15859668}, url = {https://doi.org/10.1089/jpm.2000.3.265} } @article{song2019-31373868, author = {Song, M. K. and Ward, S. E. and Hepburn, K. and Paul, S. and Kim, H. and Shah, R. C. and Morhardt, D. J. and Medders, L. and others}, title = {{Can Persons with Dementia Meaningfully Participate in Advance Care Planning Discussions? A Mixed-Methods Study of SPIRIT}}, journal = {Journal of palliative medicine}, year = {2019}, doi = {10.1089/jpm.2019.0088}, pmid = {31373868}, url = {https://doi.org/10.1089/jpm.2019.0088} } @article{goossens2020-31818522, author = {Goossens, B. and Sevenants, A. and Declercq, A. and Van Audenhove, C.}, title = {{Improving shared decision-making in advance care planning: Implementation of a cluster randomized staff intervention in dementia care}}, journal = {Patient education and counseling}, year = {2020}, doi = {10.1016/j.pec.2019.11.024}, pmid = {31818522}, url = {https://doi.org/10.1016/j.pec.2019.11.024} } @article{wagstaff2003-12885101, author = {Wagstaff, L. R. and Mitton, M. W. and Arvik, B. M. and Doraiswamy, P. M.}, title = {{Statin-associated memory loss: analysis of 60 case reports and review of the literature}}, journal = {Pharmacotherapy}, year = {2003}, doi = {10.1592/phco.23.7.871.32720}, pmid = {12885101}, url = {https://doi.org/10.1592/phco.23.7.871.32720} } @article{carney2019-31921965, author = {Carney, Greg and Bassett, Ken and Wright, James M and Maclure, Malcolm and McGuire, Nicolette and Dormuth, Colin R}, title = {{Comparison of cholinesterase inhibitor safety in real-world practice}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2019}, doi = {10.1016/j.trci.2019.09.011}, pmid = {31921965}, url = {https://doi.org/10.1016/j.trci.2019.09.011} } @article{hooper2024-38235997, author = {Hooper, Emma and Brown, Laura J E and Cross, Hannah and Dawes, Piers and Leroi, Iracema and Armitage, Christopher J}, title = {{Enablers and Barriers to Hearing aid Use in People Living With Dementia}}, journal = {Journal of applied gerontology : the official journal of the Southern Gerontological Society}, year = {2024}, doi = {10.1177/07334648231225346}, pmid = {38235997}, url = {https://doi.org/10.1177/07334648231225346} } @article{gaugler2013-23339050, author = {Gaugler, Joseph E and Reese, Mark and Mittelman, Mary S}, title = {{Effects of the NYU caregiver intervention-adult child on residential care placement}}, journal = {The Gerontologist}, year = {2013}, doi = {10.1093/geront/gns193}, pmid = {23339050}, url = {https://doi.org/10.1093/geront/gns193} } @article{araki2020-7f71ce0b, author = {Araki, Eiichi and Goto, Atsushi and Kondo, Tatsuya and Noda, Mitsuhiko and Noto, Hiroshi and Origasa, Hideki and Osawa, Haruhiko and Taguchi, Akihiko and others}, title = {{Japanese Clinical Practice Guideline for Diabetes 2019}}, journal = {Journal of Diabetes Investigation}, year = {2020}, doi = {10.1111/jdi.13306}, url = {https://doi.org/10.1111/jdi.13306} } @article{boustani2025-41212562, author = {Boustani, M. A. and Ben Miled, Z. and Owora, A. H. and Fowler, N. R. and Dexter, P. and Puster, E. and Grout, R. W. and Summanwar, D. and Erazo, S. F. and Disla, S. and others}, title = {{Digital Detection of Dementia in Primary Care: A Randomized Clinical Trial}}, journal = {JAMA Network Open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.42222}, pmid = {41212562}, url = {https://doi.org/10.1001/jamanetworkopen.2025.42222} } @article{geldmacher2011-20837824, author = {Geldmacher, D. S. and Fritsch, T. and McClendon, M. J. and Landreth, G.}, title = {{A randomized pilot clinical trial of the safety of pioglitazone in treatment of patients with Alzheimer disease}}, journal = {Archives of neurology}, year = {2011}, doi = {10.1001/archneurol.2010.229}, pmid = {20837824}, url = {https://doi.org/10.1001/archneurol.2010.229} } @article{djaiani2016-26575144, author = {Djaiani, G. and Silverton, N. and Fedorko, L. and Carroll, J. and Styra, R. and Rao, V. and Katznelson, R.}, title = {{Dexmedetomidine versus Propofol Sedation Reduces Delirium after Cardiac Surgery: A Randomized Controlled Trial}}, journal = {Anesthesiology}, year = {2016}, doi = {10.1097/aln.0000000000000951}, pmid = {26575144}, url = {https://doi.org/10.1097/aln.0000000000000951} } @article{phillips2021-33622392, author = {Phillips, M. C. L. and Deprez, L. M. and Mortimer, G. M. N. and Murtagh, D. K. J. and McCoy, S. and Mylchreest, R. and Gilbertson, L. J. and Clark, K. M. and others}, title = {{Randomized crossover trial of a modified ketogenic diet in Alzheimer's disease}}, journal = {Alzheimer's research \& therapy}, year = {2021}, doi = {10.1186/s13195-021-00783-x}, pmid = {33622392}, url = {https://doi.org/10.1186/s13195-021-00783-x} } @article{corbett2015-26543007, author = {Corbett, A. and Owen, A. and Hampshire, A. and Grahn, J. and Stenton, R. and Dajani, S. and Burns, A. and Howard, R. and others}, title = {{The Effect of an Online Cognitive Training Package in Healthy Older Adults: An Online Randomized Controlled Trial}}, journal = {Journal of the American Medical Directors Association}, year = {2015}, doi = {10.1016/j.jamda.2015.06.014}, pmid = {26543007}, url = {https://doi.org/10.1016/j.jamda.2015.06.014} } @article{bartlett2000-10987697, author = {Bartlett, John Gilles and Dowell, Scott F. and Mandell, Lionel A. and File, Thomas M. and Musher, Daniel M. and Fine, Michael J.}, title = {{Practice Guidelines for the Management of Community-Acquired Pneumonia in Adults}}, journal = {Clinical Infectious Diseases}, year = {2000}, doi = {10.1086/313954}, pmid = {10987697}, url = {https://doi.org/10.1086/313954} } @article{zhang2025-40425261, author = {Zhang, Xingyi and Wang, Siming and Zhou, Xingyu and Tang, Ya‐Jie and Xing, Liying and Ma, Shaoning and Yan, Xu and Wu, Chaoqun and others}, title = {{A village doctor-led mobile health intervention for cardiovascular risk reduction in rural China: cluster randomised controlled trial}}, journal = {BMJ}, year = {2025}, doi = {10.1136/bmj-2024-082765}, pmid = {40425261}, url = {https://doi.org/10.1136/bmj-2024-082765} } @article{barbera2018-29480185, author = {Barbera, M. and Mangialasche, F. and Jongstra, S. and Guillemont, J. and Ngandu, T. and Beishuizen, C. and Coley, N. and Brayne, C. and others}, title = {{Designing an Internet-Based Multidomain Intervention for the Prevention of Cardiovascular Disease and Cognitive Impairment in Older Adults: The HATICE Trial}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2018}, doi = {10.3233/jad-170858}, pmid = {29480185}, url = {https://doi.org/10.3233/jad-170858} } @article{knapp2006-16738349, author = {Knapp, M. and Thorgrimsen, L. and Patel, A. and Spector, A. and Hallam, A. and Woods, B. and Orrell, M.}, title = {{Cognitive stimulation therapy for people with dementia: cost-effectiveness analysis}}, journal = {The British journal of psychiatry : the journal of mental science}, year = {2006}, doi = {10.1192/bjp.bp.105.010561}, pmid = {16738349}, url = {https://doi.org/10.1192/bjp.bp.105.010561} } @article{kwok2025-40094667, author = {Kwok, J. Y. Y. and Cheung, D. S. K. and Zarit, S. and Cheung, K. S. and Lau, B. H. P. and Lou, V. W. and Cheng, S. T. and Gallagher-Thompson, D. and Qian, M. and Chou, K. L.}, title = {{Multicomponent Intervention for Distressed Informal Caregivers of People With Dementia: A Randomized Clinical Trial}}, journal = {JAMA Network Open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.0069}, pmid = {40094667}, url = {https://doi.org/10.1001/jamanetworkopen.2025.0069} } @article{watt2020-32546202, author = {Watt, J. A. and Goodarzi, Z. and Veroniki, A. A. and Nincic, V. and Khan, P. A. and Ghassemi, M. and Thompson, Y. and Lai, Y. and others}, title = {{Safety of pharmacologic interventions for neuropsychiatric symptoms in dementia: a systematic review and network meta-analysis}}, journal = {BMC geriatrics}, year = {2020}, doi = {10.1186/s12877-020-01607-7}, pmid = {32546202}, url = {https://doi.org/10.1186/s12877-020-01607-7} } @article{higgins2003-12917896, author = {Higgins, J. P. and Flicker, L.}, title = {{Lecithin for dementia and cognitive impairment}}, journal = {The Cochrane database of systematic reviews}, year = {2003}, doi = {10.1002/14651858.cd001015}, pmid = {12917896}, url = {https://doi.org/10.1002/14651858.cd001015} } @article{andre2023-37258299, author = {André, C. and Kuhn, E. and Rehel, S. and Ourry, V. and Demeilliez-Servouin, S. and Palix, C. and Felisatti, F. and Champetier, P. and others}, title = {{Association of Sleep-Disordered Breathing and Medial Temporal Lobe Atrophy in Cognitively Unimpaired Amyloid-Positive Older Adults}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000207421}, pmid = {37258299}, url = {https://doi.org/10.1212/wnl.0000000000207421} } @article{marcum2023-36598787, author = {Marcum, Z. A. and Gabriel, N. and Bress, A. P. and Hernandez, I.}, title = {{Association of New Use of Antihypertensives That Stimulate vs Inhibit Type 2 and 4 Angiotensin II Receptors With Dementia Among Medicare Beneficiaries}}, journal = {JAMA network open}, year = {2023}, doi = {10.1001/jamanetworkopen.2022.49370}, pmid = {36598787}, url = {https://doi.org/10.1001/jamanetworkopen.2022.49370} } @article{mclachlan1992-1490430, author = {McLachlan, D. R. and Fraser, P. E. and Dalton, A. J.}, title = {{Aluminium and the pathogenesis of Alzheimer's disease: a summary of evidence}}, journal = {Ciba Foundation symposium}, year = {1992}, doi = {10.1002/9780470514306.ch6}, pmid = {1490430}, url = {https://doi.org/10.1002/9780470514306.ch6} } @article{lisko2021-33314384, author = {Lisko, I. and Kulmala, J. and Annetorp, M. and Ngandu, T. and Mangialasche, F. and Kivipelto, M.}, title = {{How can dementia and disability be prevented in older adults: where are we today and where are we going?}}, journal = {Journal of internal medicine}, year = {2021}, doi = {10.1111/joim.13227}, pmid = {33314384}, url = {https://doi.org/10.1111/joim.13227} } @article{prince2007-17659078, author = {Prince, M. and Ferri, C. P. and Acosta, D. and Albanese, E. and Arizaga, R. and Dewey, M. and Gavrilova, S. I. and Guerra, M. and others}, title = {{The protocols for the 10/66 dementia research group population-based research programme}}, journal = {BMC public health}, year = {2007}, doi = {10.1186/1471-2458-7-165}, pmid = {17659078}, url = {https://doi.org/10.1186/1471-2458-7-165} } @article{mervin2018-29325922, author = {Mervin, M. C. and Moyle, W. and Jones, C. and Murfield, J. and Draper, B. and Beattie, E. and Shum, D. H. K. and O'Dwyer, S. and others}, title = {{The Cost-Effectiveness of Using PARO, a Therapeutic Robotic Seal, to Reduce Agitation and Medication Use in Dementia: Findings from a Cluster-Randomized Controlled Trial}}, journal = {Journal of the American Medical Directors Association}, year = {2018}, doi = {10.1016/j.jamda.2017.10.008}, pmid = {29325922}, url = {https://doi.org/10.1016/j.jamda.2017.10.008} } @article{mcadamsdemarco2018-29340317, author = {McAdams-DeMarco, M. A. and Konel, J. and Warsame, F. and Ying, H. and González Fernández, M. and Carlson, M. C. and Fine, D. M. and Appel, L. J. and others}, title = {{Intradialytic Cognitive and Exercise Training May Preserve Cognitive Function}}, journal = {Kidney international reports}, year = {2018}, doi = {10.1016/j.ekir.2017.08.006}, pmid = {29340317}, url = {https://doi.org/10.1016/j.ekir.2017.08.006} } @article{buitenweg2017-29209183, author = {Buitenweg, J. I. V. and van de Ven, R. M. and Prinssen, S. and Murre, J. M. J. and Ridderinkhof, K. R.}, title = {{Cognitive Flexibility Training: A Large-Scale Multimodal Adaptive Active-Control Intervention Study in Healthy Older Adults}}, journal = {Frontiers in human neuroscience}, year = {2017}, doi = {10.3389/fnhum.2017.00529}, pmid = {29209183}, url = {https://doi.org/10.3389/fnhum.2017.00529} } @article{murukesu2020-33014971, author = {Murukesu, R. R. and Singh, D. K. A. and Shahar, S. and Subramaniam, P.}, title = {{A Multi-Domain Intervention Protocol for the Potential Reversal of Cognitive Frailty: "WE-RISE" Randomized Controlled Trial}}, journal = {Frontiers in public health}, year = {2020}, doi = {10.3389/fpubh.2020.00471}, pmid = {33014971}, url = {https://doi.org/10.3389/fpubh.2020.00471} } @article{mcmaster2018-30538436, author = {McMaster, M. and Kim, S. and Clare, L. and Torres, S. J. and D'Este, C. and Anstey, K. J.}, title = {{Body, Brain, Life for Cognitive Decline (BBL-CD): protocol for a multidomain dementia risk reduction randomized controlled trial for subjective cognitive decline and mild cognitive impairment}}, journal = {Clinical interventions in aging}, year = {2018}, doi = {10.2147/cia.s182046}, pmid = {30538436}, url = {https://doi.org/10.2147/cia.s182046} } @article{hanson2011-22091750, author = {Hanson, L. C. and Carey, T. S. and Caprio, A. J. and Lee, T. J. and Ersek, M. and Garrett, J. and Jackman, A. and Gilliam, R. and others}, title = {{Improving decision-making for feeding options in advanced dementia: a randomized, controlled trial}}, journal = {Journal of the American Geriatrics Society}, year = {2011}, doi = {10.1111/j.1532-5415.2011.03629.x}, pmid = {22091750}, url = {https://doi.org/10.1111/j.1532-5415.2011.03629.x} } @article{reinhardt2014-24835382, author = {Reinhardt, J. P. and Chichin, E. and Posner, L. and Kassabian, S.}, title = {{Vital conversations with family in the nursing home: preparation for end-stage dementia care}}, journal = {Journal of social work in end-of-life \& palliative care}, year = {2014}, doi = {10.1080/15524256.2014.906371}, pmid = {24835382}, url = {https://doi.org/10.1080/15524256.2014.906371} } @article{smaling2018-30327407, author = {Smaling, H. J. A. and Joling, K. J. and van de Ven, P. M. and Bosmans, J. E. and Simard, J. and Volicer, L. and Achterberg, W. P. and Francke, A. L. and others}, title = {{Effects of the Namaste Care Family programme on quality of life of nursing home residents with advanced dementia and on family caregiving experiences: study protocol of a cluster-randomised controlled trial}}, journal = {BMJ open}, year = {2018}, doi = {10.1136/bmjopen-2018-025411}, pmid = {30327407}, url = {https://doi.org/10.1136/bmjopen-2018-025411} } @article{scheewe2013-22981376, author = {Scheewe, T. W. and van Haren, N. E. and Sarkisyan, G. and Schnack, H. G. and Brouwer, R. M. and de Glint, M. and Hulshoff Pol, H. E. and Backx, F. J. and others}, title = {{Exercise therapy, cardiorespiratory fitness and their effect on brain volumes: a randomised controlled trial in patients with schizophrenia and healthy controls}}, journal = {European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology}, year = {2013}, doi = {10.1016/j.euroneuro.2012.08.008}, pmid = {22981376}, url = {https://doi.org/10.1016/j.euroneuro.2012.08.008} } @article{ashworth2026-6293a8b2, author = {Ashworth, J. and Cornwall, N. and Harrisson, S. A. and Woodcock, C. and Nicholls, E. and Hughes, G. and Marshall, E. and Lawton, S. A. and others}, title = {{Evaluating a primary care pharmacist-led intervention to reduce opioid use for persistent non-cancer pain: the PROMPPT cluster randomised controlled trial protocol}}, journal = {NIHR Open Res}, year = {2026}, doi = {10.3310/nihropenres.13961.4}, url = {https://doi.org/10.3310/nihropenres.13961.4} } @article{gilbert2018-30508430, author = {Gilbert, Matthew Philip and Bain, Stephen Charles and Franek, Edward and Jódar-Gimeno, Esteban and Nauck, Michael Albrecht and Pratley, Richard E. and Rea, Rosangela Roginski and Saraiva, José Francisco Kerr and others}, title = {{Effect of Liraglutide on Cardiovascular Outcomes in Elderly Patients: A Post Hoc Analysis of a Randomized Controlled Trial}}, journal = {Annals of Internal Medicine}, year = {2018}, doi = {10.7326/m18-1569}, pmid = {30508430}, url = {https://doi.org/10.7326/m18-1569} } @article{isaaq2025-39978389, author = {Isaaq, A. and Cooper, C. and Vickerstaff, V. and Barber, J. A. and Walters, K. and Lang, I. A. and Rapaport, P. and Orgeta, V. and Rockwood, K. and Butler, L. T. and Lord, K. and Livingston, G. and others}, title = {{Cost-utility of a new psychosocial goal-setting and manualised support intervention for independence in dementia (NIDUS-Family) versus goal setting and routine care: an economic evaluation embedded within a randomised controlled trial}}, journal = {The Lancet Healthy Longevity}, year = {2025}, doi = {10.1016/j.lanhl.2024.100676}, pmid = {39978389}, url = {https://doi.org/10.1016/j.lanhl.2024.100676} } @article{shao2012-23100399, author = {Shao, H. and Breitner, J. C. and Whitmer, R. A. and Wang, J. and Hayden, K. and Wengreen, H. and Corcoran, C. and Tschanz, J. and others}, title = {{Hormone therapy and Alzheimer disease dementia: new findings from the Cache County Study}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e318271f823}, pmid = {23100399}, url = {https://doi.org/10.1212/wnl.0b013e318271f823} } @article{bayercarter2011-21670398, author = {Bayer-Carter, J. L. and Green, P. S. and Montine, T. J. and VanFossen, B. and Baker, L. D. and Watson, G. S. and Bonner, L. M. and Callaghan, M. and others}, title = {{Diet intervention and cerebrospinal fluid biomarkers in amnestic mild cognitive impairment}}, journal = {Archives of neurology}, year = {2011}, doi = {10.1001/archneurol.2011.125}, pmid = {21670398}, url = {https://doi.org/10.1001/archneurol.2011.125} } @article{fowler2020-31792940, author = {Fowler, N. R. and Perkins, A. J. and Gao, S. and Sachs, G. A. and Boustani, M. A.}, title = {{Risks and Benefits of Screening for Dementia in Primary Care: The Indiana University Cognitive Health Outcomes Investigation of the Comparative Effectiveness of Dementia Screening (IU CHOICE)Trial}}, journal = {Journal of the American Geriatrics Society}, year = {2020}, doi = {10.1111/jgs.16247}, pmid = {31792940}, url = {https://doi.org/10.1111/jgs.16247} } @article{anstey2020-32969833, author = {Anstey, K. J. and Cherbuin, N. and Kim, S. and McMaster, M. and D'Este, C. and Lautenschlager, N. and Rebok, G. and McRae, I. and others}, title = {{An Internet-Based Intervention Augmented With a Diet and Physical Activity Consultation to Decrease the Risk of Dementia in At-Risk Adults in a Primary Care Setting: Pragmatic Randomized Controlled Trial}}, journal = {Journal of medical Internet research}, year = {2020}, doi = {10.2196/19431}, pmid = {32969833}, url = {https://doi.org/10.2196/19431} } @article{dubbelman2025-40440591, author = {Dubbelman, M. A. and Liu, A. and Donohue, M. C. and Langford, O. and Raman, R. and Rentz, D. M. and Amariglio, R. and Sperling, R. A. and others}, title = {{Changes in Daily Functioning in Association With Tau and Amyloid Among Unimpaired Older Adults With and Without Elevated Amyloid}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000213775}, pmid = {40440591}, url = {https://doi.org/10.1212/wnl.0000000000213775} } @article{turpin2025-39919257, author = {Turpin, A. L. and Felisatti, F. and Chauveau, L. and Haudry, S. and Mézenge, F. and Landeau, B. and Vivien, D. and De La Sayette, V. and others}, title = {{Association Between Lifestyle at Different Life Periods and Brain Integrity in Older Adults}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000213347}, pmid = {39919257}, url = {https://doi.org/10.1212/wnl.0000000000213347} } @article{watne2014-24735588, author = {Watne, L. O. and Torbergsen, A. C. and Conroy, S. and Engedal, K. and Frihagen, F. and Hjorthaug, G. A. and Juliebo, V. and Raeder, J. and others}, title = {{The effect of a pre- and postoperative orthogeriatric service on cognitive function in patients with hip fracture: randomized controlled trial (Oslo Orthogeriatric Trial)}}, journal = {BMC medicine}, year = {2014}, doi = {10.1186/1741-7015-12-63}, pmid = {24735588}, url = {https://doi.org/10.1186/1741-7015-12-63} } @article{neumann2022-34762275, author = {Neumann, J. T. and Thao, L. T. P. and Callander, E. and Chowdhury, E. and Williamson, J. D. and Nelson, M. R. and Donnan, G. and Woods, R. L. and others}, title = {{Cardiovascular risk prediction in healthy older people}}, journal = {GeroScience}, year = {2022}, doi = {10.1007/s11357-021-00486-z}, pmid = {34762275}, url = {https://doi.org/10.1007/s11357-021-00486-z} } @article{rojassaunero2023-37139580, author = {Rojas-Saunero, L. P. and Young, J. G. and Didelez, V. and Ikram, M. A. and Swanson, S. A.}, title = {{Considering Questions Before Methods in Dementia Research With Competing Events and Causal Goals}}, journal = {American journal of epidemiology}, year = {2023}, doi = {10.1093/aje/kwad090}, pmid = {37139580}, url = {https://doi.org/10.1093/aje/kwad090} } @article{ponvel2025-40361174, author = {Ponvel, Pavapriya and Shahar, Suzana and Singh, Devinder Kaur Ajit and Ludin, Arimi Fitri Mat and Subramaniam, Ponnusamy and Ibrahim, Norhayati and Haron, Hasnah and Ismail, Aniza Binti and others}, title = {{The cost effectiveness of a multidomain intervention on physical, cognitive, vascular, dietary and psychosocial outcomes among community dwelling older adults with cognitive frailty in Malaysia: The AGELESS Trial}}, journal = {Alzheimer s Research \& Therapy}, year = {2025}, doi = {10.1186/s13195-025-01722-w}, pmid = {40361174}, url = {https://doi.org/10.1186/s13195-025-01722-w} } @article{demnitzking2025-41130254, author = {Demnitz-King, H. and Adeleke, M. and Barber, J. A. and Poppe, M. and Budgett, J. and Alberts, S. and Duffy, L. and Minihane, A. M. and Gillings, R. and Chapman, H. and others}, title = {{Remote, lower-intensity, multidomain lifestyle intervention for subjective cognitive decline or mild cognitive impairment (APPLE-Tree): a multicentre, single-masked, randomised controlled trial}}, journal = {The Lancet Healthy Longevity}, year = {2025}, doi = {10.1016/j.lanhl.2025.100777}, pmid = {41130254}, url = {https://doi.org/10.1016/j.lanhl.2025.100777} } @article{fernandezgamez2026-41562376, author = {Fernandez-Gamez, B. and Solis-Urra, P. and Coca-Pulido, A. and Molina-Hidalgo, C. and Olvera-Rojas, M. and Bakker, E. A. and others}, title = {{Effect of a 24-week resistance exercise intervention on cognitive function in cognitively normal older adults: The AGUEDA randomized controlled trial}}, journal = {Alzheimer's \& Dementia}, year = {2026}, doi = {10.1002/alz.71019}, pmid = {41562376}, url = {https://doi.org/10.1002/alz.71019} } @article{saadmaan2026-40747850, author = {Saadmaan, Gazi and Dalmasso, Maria Carolina and Maria, Maleeha and Lehtisalo, Jenni and Hiltunen, Mikko and Kaikkonen, Minna U and Levälahti, Esko and Mangialasche, Francesca and others}, title = {{Alzheimer and cardiovascular genetic scores and cognition: the FINGER randomized controlled trial}}, journal = {Brain : a journal of neurology}, year = {2026}, doi = {10.1093/brain/awaf277}, pmid = {40747850}, url = {https://doi.org/10.1093/brain/awaf277} } @article{deheus2019-31542965, author = {de Heus, R. A. A. and Olde Rikkert, M. G. M. and Tully, P. J. and Lawlor, B. A. and Claassen, J. A. H. R. and {NILVAD Study Group}}, title = {{Blood Pressure Variability and Progression of Clinical Alzheimer Disease}}, journal = {Hypertension (Dallas, Tex. : 1979)}, year = {2019}, doi = {10.1161/hypertensionaha.119.13664}, pmid = {31542965}, url = {https://doi.org/10.1161/hypertensionaha.119.13664} } @article{delgadoperaza2023-37730689, author = {Delgado-Peraza, F. and Nogueras-Ortiz, C. and Simonsen, A. H. and Knight, D. D. and Yao, P. J. and Goetzl, E. J. and Jensen, C. S. and Høgh, P. and others}, title = {{Neuron-derived extracellular vesicles in blood reveal effects of exercise in Alzheimer's disease}}, journal = {Alzheimer's research \& therapy}, year = {2023}, doi = {10.1186/s13195-023-01303-9}, pmid = {37730689}, url = {https://doi.org/10.1186/s13195-023-01303-9} } @article{cheung2023-36767702, author = {Cheung, T. and Li, T. M. H. and Ho, Y. S. and Kranz, G. and Fong, K. N. K. and Leung, S. F. and Lam, S. C. and Yeung, W. F. and others}, title = {{Effects of Transcranial Pulse Stimulation (TPS) on Adults with Symptoms of Depression-A Pilot Randomized Controlled Trial}}, journal = {International journal of environmental research and public health}, year = {2023}, doi = {10.3390/ijerph20032333}, pmid = {36767702}, url = {https://doi.org/10.3390/ijerph20032333} } @article{villardita1992-1603291, author = {Villardita, C. and Grioli, S. and Lomeo, C. and Cattaneo, C. and Parini, J.}, title = {{Clinical studies with oxiracetam in patients with dementia of Alzheimer type and multi-infarct dementia of mild to moderate degree}}, journal = {Neuropsychobiology}, year = {1992}, doi = {10.1159/000118805}, pmid = {1603291}, url = {https://doi.org/10.1159/000118805} } @article{wetmore2024-39748836, author = {Wetmore, J. B. and Rodriguez, S. and Diaz Caro, D. and Cabán, M. and Uhlmann, W. and Goldman, J. and Leu, C. S. and Godinez, J. D. and others}, title = {{Designing and implementing the IDEAL Study: A randomized clinical trial of APOE genotype disclosure for late-onset Alzheimer's disease in an urban Latino population}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2024}, doi = {10.1002/trc2.70016}, pmid = {39748836}, url = {https://doi.org/10.1002/trc2.70016} } @article{thapa2020-32365533, author = {Thapa, N. and Park, H. J. and Yang, J. G. and Son, H. and Jang, M. and Lee, J. and Kang, S. W. and Park, K. W. and others}, title = {{The Effect of a Virtual Reality-Based Intervention Program on Cognition in Older Adults with Mild Cognitive Impairment: A Randomized Control Trial}}, journal = {Journal of clinical medicine}, year = {2020}, doi = {10.3390/jcm9051283}, pmid = {32365533}, url = {https://doi.org/10.3390/jcm9051283} } @article{lam2015-25826620, author = {Lam, L. C. and Chan, W. C. and Leung, T. and Fung, A. W. and Leung, E. M.}, title = {{Would older adults with mild cognitive impairment adhere to and benefit from a structured lifestyle activity intervention to enhance cognition?: a cluster randomized controlled trial}}, journal = {PloS one}, year = {2015}, doi = {10.1371/journal.pone.0118173}, pmid = {25826620}, url = {https://doi.org/10.1371/journal.pone.0118173} } @article{niemann2014-25165446, author = {Niemann, C. and Godde, B. and Voelcker-Rehage, C.}, title = {{Not only cardiovascular, but also coordinative exercise increases hippocampal volume in older adults}}, journal = {Frontiers in aging neuroscience}, year = {2014}, doi = {10.3389/fnagi.2014.00170}, pmid = {25165446}, url = {https://doi.org/10.3389/fnagi.2014.00170} } @article{schwarzkopf2011-21914502, author = {Schwarzkopf, L. and Menn, P. and Kunz, S. and Holle, R. and Lauterberg, J. and Marx, P. and Mehlig, H. and Wunder, S. and others}, title = {{Costs of care for dementia patients in community setting: an analysis for mild and moderate disease stage}}, journal = {Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research}, year = {2011}, doi = {10.1016/j.jval.2011.04.005}, pmid = {21914502}, url = {https://doi.org/10.1016/j.jval.2011.04.005} } @article{shekelle2001-11601948, author = {Shekelle, Paul and MacLean, Catherine H. and Morton, Sally C. and Wenger, Neil S.}, title = {{ACOVE Quality Indicators}}, journal = {Annals of Internal Medicine}, year = {2001}, doi = {10.7326/0003-4819-135-8_part_2-200110161-00004}, pmid = {11601948}, url = {https://doi.org/10.7326/0003-4819-135-8_part_2-200110161-00004} } @article{lourida2013-23680940, author = {Lourida, I. and Soni, M. and Thompson-Coon, J. and Purandare, N. and Lang, I. A. and Ukoumunne, O. C. and Llewellyn, D. J.}, title = {{Mediterranean diet, cognitive function, and dementia: a systematic review}}, journal = {Epidemiology (Cambridge, Mass.)}, year = {2013}, doi = {10.1097/ede.0b013e3182944410}, pmid = {23680940}, url = {https://doi.org/10.1097/ede.0b013e3182944410} } @article{clare2010-20808145, author = {Clare, L. and Linden, D. E. and Woods, R. T. and Whitaker, R. and Evans, S. J. and Parkinson, C. H. and van Paasschen, J. and Nelis, S. M. and others}, title = {{Goal-oriented cognitive rehabilitation for people with early-stage Alzheimer disease: a single-blind randomized controlled trial of clinical efficacy}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2010}, doi = {10.1097/jgp.0b013e3181d5792a}, pmid = {20808145}, url = {https://doi.org/10.1097/jgp.0b013e3181d5792a} } @article{linnenbringer2010-20139767, author = {Linnenbringer, E. and Roberts, J. S. and Hiraki, S. and Cupples, L. A. and Green, R. C.}, title = {{"I know what you told me, but this is what I think:" perceived risk of Alzheimer disease among individuals who accurately recall their genetics-based risk estimate}}, journal = {Genetics in medicine : official journal of the American College of Medical Genetics}, year = {2010}, doi = {10.1097/gim.0b013e3181cef9e1}, pmid = {20139767}, url = {https://doi.org/10.1097/gim.0b013e3181cef9e1} } @article{hooper2017-29083439, author = {Hooper, C. and De Souto Barreto, P. and Coley, N. and Cantet, C. and Cesari, M. and Andrieu, S. and Vellas, B.}, title = {{Cognitive Changes with Omega-3 Polyunsaturated Fatty Acids in Non-Demented Older Adults with Low Omega-3 Index}}, journal = {The journal of nutrition, health \& aging}, year = {2017}, doi = {10.1007/s12603-017-0957-5}, pmid = {29083439}, url = {https://doi.org/10.1007/s12603-017-0957-5} } @article{vidoni2019-29286983, author = {Vidoni, E. D. and Perales, J. and Alshehri, M. and Giles, A. M. and Siengsukon, C. F. and Burns, J. M.}, title = {{Aerobic Exercise Sustains Performance of Instrumental Activities of Daily Living in Early-Stage Alzheimer Disease}}, journal = {Journal of geriatric physical therapy (2001)}, year = {2019}, doi = {10.1519/jpt.0000000000000172}, pmid = {29286983}, url = {https://doi.org/10.1519/jpt.0000000000000172} } @article{sevinc2021-34512305, author = {Sevinc, G. and Rusche, J. and Wong, B. and Datta, T. and Kaufman, R. and Gutz, S. E. and Schneider, M. and Todorova, N. and others}, title = {{Mindfulness Training Improves Cognition and Strengthens Intrinsic Connectivity Between the Hippocampus and Posteromedial Cortex in Healthy Older Adults}}, journal = {Frontiers in aging neuroscience}, year = {2021}, doi = {10.3389/fnagi.2021.702796}, pmid = {34512305}, url = {https://doi.org/10.3389/fnagi.2021.702796} } @article{viswanathan2009-19153374, author = {Viswanathan, A. and Raj, S. and Greenberg, S. M. and Stampfer, M. and Campbell, S. and Hyman, B. T. and Irizarry, M. C.}, title = {{Plasma Abeta, homocysteine, and cognition: the Vitamin Intervention for Stroke Prevention (VISP) trial}}, journal = {Neurology}, year = {2009}, doi = {10.1212/01.wnl.0000339486.63862.db}, pmid = {19153374}, url = {https://doi.org/10.1212/01.wnl.0000339486.63862.db} } @article{flo2022-35771851, author = {Flo, B. K. and Matziorinis, A. M. and Skouras, S. and Sudmann, T. T. and Gold, C. and Koelsch, S.}, title = {{Study protocol for the Alzheimer and music therapy study: An RCT to compare the efficacy of music therapy and physical activity on brain plasticity, depressive symptoms, and cognitive decline, in a population with and at risk for Alzheimer's disease}}, journal = {PloS one}, year = {2022}, doi = {10.1371/journal.pone.0270682}, pmid = {35771851}, url = {https://doi.org/10.1371/journal.pone.0270682} } @article{ellis2019-29059120, author = {Ellis, J. L. and Altenburger, P. and Lu, Y.}, title = {{Change in Depression, Confidence, and Physical Function Among Older Adults With Mild Cognitive Impairment}}, journal = {Journal of geriatric physical therapy (2001)}, year = {2019}, doi = {10.1519/jpt.0000000000000143}, pmid = {29059120}, url = {https://doi.org/10.1519/jpt.0000000000000143} } @article{sinn2012-21929835, author = {Sinn, N. and Milte, C. M. and Street, S. J. and Buckley, J. D. and Coates, A. M. and Petkov, J. and Howe, P. R.}, title = {{Effects of n-3 fatty acids, EPA v. DHA, on depressive symptoms, quality of life, memory and executive function in older adults with mild cognitive impairment: a 6-month randomised controlled trial}}, journal = {The British journal of nutrition}, year = {2012}, doi = {10.1017/s0007114511004788}, pmid = {21929835}, url = {https://doi.org/10.1017/s0007114511004788} } @article{song2019-30901716, author = {Song, D. and Yu, D. S. F.}, title = {{Effects of a moderate-intensity aerobic exercise programme on the cognitive function and quality of life of community-dwelling elderly people with mild cognitive impairment: A randomised controlled trial}}, journal = {International journal of nursing studies}, year = {2019}, doi = {10.1016/j.ijnurstu.2019.02.019}, pmid = {30901716}, url = {https://doi.org/10.1016/j.ijnurstu.2019.02.019} } @article{bouchelit2026-8f7376fd, author = {Bouchelit, Mohammed El Amin}, title = {{Stress-Specific Mitochondrial Reserve as a Candidate Modifier of Lipid-Driven Synaptic Failure in Alzheimer Disease}}, journal = {Zenodo (CERN European Organization for Nuclear Research)}, year = {2026}, doi = {10.5281/zenodo.21854146}, url = {https://doi.org/10.5281/zenodo.21854146} } @article{yu2025-39835654, author = {Yu, Ruan‐Ching and Pavlou, Menelaos and Schilder, Anne GM and Bamiou, Doris‐Eva and Lewis, Glyn and Lin, Frank Robert and Livingston, Gill and Proctor, Danielle and others}, title = {{Early detection and management of hearing loss to reduce dementia risk in older adults with mild cognitive impairment: findings from the treating auditory impairment and cognition trial (TACT)}}, journal = {Age and Ageing}, year = {2025}, doi = {10.1093/ageing/afaf004}, pmid = {39835654}, url = {https://doi.org/10.1093/ageing/afaf004} } @article{moon2025-39840755, author = {Moon, So Young and Park, Yoo Kyoung and Jeong, Jee Hyang and Hong, Chang Hyung and Jung, Jiwoo and Na, Hae Ri and Cho, Soo Hyun and Kim, Hyun Sook and others}, title = {{South Korean study to prevent cognitive impairment and protect brain health through multidomain interventions via face‐to‐face and video communication platforms in mild cognitive impairment (SUPERBRAIN‐MEET): A randomized controlled trial}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.14517}, pmid = {39840755}, url = {https://doi.org/10.1002/alz.14517} } @article{scheltens2018-30309389, author = {Scheltens, P. and Hallikainen, M. and Grimmer, T. and Duning, T. and Gouw, A. A. and Teunissen, C. E. and Wink, A. M. and Maruff, P. and others}, title = {{Safety, tolerability and efficacy of the glutaminyl cyclase inhibitor PQ912 in Alzheimer's disease: results of a randomized, double-blind, placebo-controlled phase 2a study}}, journal = {Alzheimer's research \& therapy}, year = {2018}, doi = {10.1186/s13195-018-0431-6}, pmid = {30309389}, url = {https://doi.org/10.1186/s13195-018-0431-6} } @article{lawrence2017-28583011, author = {Lawrence, B. J. and Gasson, N. and Bucks, R. S. and Troeung, L. and Loftus, A. M.}, title = {{Cognitive Training and Noninvasive Brain Stimulation for Cognition in Parkinson's Disease: A Meta-analysis}}, journal = {Neurorehabilitation and neural repair}, year = {2017}, doi = {10.1177/1545968317712468}, pmid = {28583011}, url = {https://doi.org/10.1177/1545968317712468} } @article{galik2017-27776986, author = {Galik, E. and Resnick, B. and Vigne, E. and Holmes, S. D. and Nalls, V.}, title = {{Reliability and Validity of the Resistiveness to Care Scale Among Cognitively Impaired Older Adults}}, journal = {Journal of the American Medical Directors Association}, year = {2017}, doi = {10.1016/j.jamda.2016.08.008}, pmid = {27776986}, url = {https://doi.org/10.1016/j.jamda.2016.08.008} } @article{luckett2017-28651659, author = {Luckett, T. and Chenoweth, L. and Phillips, J. and Brooks, D. and Cook, J. and Mitchell, G. and Pond, D. and Davidson, P. M. and others}, title = {{A facilitated approach to family case conferencing for people with advanced dementia living in nursing homes: perceptions of palliative care planning coordinators and other health professionals in the IDEAL study}}, journal = {International psychogeriatrics}, year = {2017}, doi = {10.1017/s1041610217000977}, pmid = {28651659}, url = {https://doi.org/10.1017/s1041610217000977} } @article{dawes2019-30244688, author = {Dawes, P. and Wolski, L. and Himmelsbach, I. and Regan, J. and Leroi, I.}, title = {{Interventions for hearing and vision impairment to improve outcomes for people with dementia: a scoping review}}, journal = {International psychogeriatrics}, year = {2019}, doi = {10.1017/s1041610218000728}, pmid = {30244688}, url = {https://doi.org/10.1017/s1041610218000728} } @article{bhasin2007-17265415, author = {Bhasin, Mani and Rowan, Elise and Edwards, Keith and McKeith, Ian}, title = {{Cholinesterase inhibitors in dementia with Lewy bodies: a comparative analysis}}, journal = {International journal of geriatric psychiatry}, year = {2007}, doi = {10.1002/gps.1759}, pmid = {17265415}, url = {https://doi.org/10.1002/gps.1759} } @article{falzarano2026-42018322, author = {Falzarano, F. B. and Greenfield, A. and Saviano, S. C. and Kolla, S. and Korian, S. and Osso, F. and Miller, J. and Whitson, H. E. and Maciejewski, P. K. and Prigerson, H. G.}, title = {{Digital Reminiscence for Predeath Grief Among Family Caregivers of Patients With Dementia: A Pilot Randomized Clinical Trial}}, journal = {JAMA Network Open}, year = {2026}, doi = {10.1001/jamanetworkopen.2026.8278}, pmid = {42018322}, url = {https://doi.org/10.1001/jamanetworkopen.2026.8278} } @article{harrison2026-42008251, author = {Harrison, T. M. and Harvey, D. J. and Chadwick, T. and Chao, Y. and Taggett, J. and Maillard, P. and Lovato, L. and Farias, S. T. and Papp, K. V. and Lockhart, S. N. and others}, title = {{Brain Imaging Biomarkers and Cognitive Outcomes in a Multidomain Lifestyle Intervention: The POINTER Imaging Ancillary Study}}, journal = {JAMA Neurology}, year = {2026}, doi = {10.1001/jamaneurol.2026.0832}, pmid = {42008251}, url = {https://doi.org/10.1001/jamaneurol.2026.0832} } @article{liuambrose2026-41795685, author = {Liu-Ambrose, T. and Falck, R. S. and Dao, E. and Crockett, R. A. and Barha, C. K. and Silva, N. C. B. S. and others}, title = {{Resistance training and subcortical vascular cognitive impairment: A 12-month randomized trial}}, journal = {Alzheimer's \& Dementia}, year = {2026}, doi = {10.1002/alz.71245}, pmid = {41795685}, url = {https://doi.org/10.1002/alz.71245} } @article{lingler2018-30094328, author = {Lingler, J. H. and Roberts, J. S. and Kim, H. and Morris, J. L. and Hu, L. and Mattos, M. and McDade, E. and Lopez, O. L.}, title = {{Amyloid positron emission tomography candidates may focus more on benefits than risks of results disclosure}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2018}, doi = {10.1016/j.dadm.2018.05.003}, pmid = {30094328}, url = {https://doi.org/10.1016/j.dadm.2018.05.003} } @article{tariot2006-16905684, author = {Tariot, P. N. and Schneider, L. and Katz, I. R. and Mintzer, J. E. and Street, J. and Copenhaver, M. and Williams-Hughes, C.}, title = {{Quetiapine treatment of psychosis associated with dementia: a double-blind, randomized, placebo-controlled clinical trial}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2006}, doi = {10.1097/01.jgp.0000196628.12010.35}, pmid = {16905684}, url = {https://doi.org/10.1097/01.jgp.0000196628.12010.35} } @article{goekoop2004-15589109, author = {Goekoop, R. and Rombouts, S. A. and Jonker, C. and Hibbel, A. and Knol, D. L. and Truyen, L. and Barkhof, F. and Scheltens, P.}, title = {{Challenging the cholinergic system in mild cognitive impairment: a pharmacological fMRI study}}, journal = {NeuroImage}, year = {2004}, doi = {10.1016/j.neuroimage.2004.08.006}, pmid = {15589109}, url = {https://doi.org/10.1016/j.neuroimage.2004.08.006} } @article{ballard2009-19700946, author = {Ballard, C. and Brown, R. and Fossey, J. and Douglas, S. and Bradley, P. and Hancock, J. and James, I. A. and Juszczak, E. and others}, title = {{Brief psychosocial therapy for the treatment of agitation in Alzheimer disease (the CALM-AD trial)}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2009}, doi = {10.1097/jgp.0b013e3181b0f8c0}, pmid = {19700946}, url = {https://doi.org/10.1097/jgp.0b013e3181b0f8c0} } @article{vellas2006-17101932, author = {Vellas, B. and Andrieu, S. and Ousset, P. J. and Ouzid, M. and Mathiex-Fortunet, H. and {GuidAge Study Group}}, title = {{The GuidAge study: methodological issues. A 5-year double-blind randomized trial of the efficacy of EGb 761 for prevention of Alzheimer disease in patients over 70 with a memory complaint}}, journal = {Neurology}, year = {2006}, doi = {10.1212/wnl.67.9_suppl_3.s6}, pmid = {17101932}, url = {https://doi.org/10.1212/wnl.67.9_suppl_3.s6} } @article{bracco2023-37875856, author = {Bracco, L. and Pinto-Carral, A. and Hillaert, L. and Mourey, F.}, title = {{Tango-therapy vs physical exercise in older people with dementia; a randomized controlled trial}}, journal = {BMC geriatrics}, year = {2023}, doi = {10.1186/s12877-023-04342-x}, pmid = {37875856}, url = {https://doi.org/10.1186/s12877-023-04342-x} } @article{demnitzking2023-37450303, author = {Demnitz-King, H. and Requier, F. and Whitfield, T. and Schlosser, M. and Gonneaud, J. and Ware, C. and Barnhofer, T. and Coll-Padros, N. and others}, title = {{Effects of Meditation Training and Non-Native Language Training on Cognition in Older Adults: A Secondary Analysis of a Randomized Clinical Trial}}, journal = {JAMA network open}, year = {2023}, doi = {10.1001/jamanetworkopen.2023.17848}, pmid = {37450303}, url = {https://doi.org/10.1001/jamanetworkopen.2023.17848} } @article{marchionni2003-12707240, author = {Marchionni, N. and Fattirolli, F. and Fumagalli, S. and Oldridge, N. and Del Lungo, F. and Morosi, L. and Burgisser, C. and Masotti, G.}, title = {{Improved exercise tolerance and quality of life with cardiac rehabilitation of older patients after myocardial infarction: results of a randomized, controlled trial}}, journal = {Circulation}, year = {2003}, doi = {10.1161/01.cir.0000066322.21016.4a}, pmid = {12707240}, url = {https://doi.org/10.1161/01.cir.0000066322.21016.4a} } @article{wang2015-25227314, author = {Wang, J. and Tan, L. and Wang, H. F. and Tan, C. C. and Meng, X. F. and Wang, C. and Tang, S. W. and Yu, J. T.}, title = {{Anti-inflammatory drugs and risk of Alzheimer's disease: an updated systematic review and meta-analysis}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2015}, doi = {10.3233/jad-141506}, pmid = {25227314}, url = {https://doi.org/10.3233/jad-141506} } @article{lam2012-22579072, author = {Lam, L. C. and Chau, R. C. and Wong, B. M. and Fung, A. W. and Tam, C. W. and Leung, G. T. and Kwok, T. C. and Leung, T. Y. and others}, title = {{A 1-year randomized controlled trial comparing mind body exercise (Tai Chi) with stretching and toning exercise on cognitive function in older Chinese adults at risk of cognitive decline}}, journal = {Journal of the American Medical Directors Association}, year = {2012}, doi = {10.1016/j.jamda.2012.03.008}, pmid = {22579072}, url = {https://doi.org/10.1016/j.jamda.2012.03.008} } @article{turner2004-15271637, author = {Turner, S. and Iliffe, S. and Downs, M. and Wilcock, J. and Bryans, M. and Levin, E. and Keady, J. and O'Carroll, R.}, title = {{General practitioners' knowledge, confidence and attitudes in the diagnosis and management of dementia}}, journal = {Age and ageing}, year = {2004}, doi = {10.1093/ageing/afh140}, pmid = {15271637}, url = {https://doi.org/10.1093/ageing/afh140} } @article{gitlin2010-20662955, author = {Gitlin, L. N. and Winter, L. and Dennis, M. P. and Hodgson, N. and Hauck, W. W.}, title = {{Targeting and managing behavioral symptoms in individuals with dementia: a randomized trial of a nonpharmacological intervention}}, journal = {Journal of the American Geriatrics Society}, year = {2010}, doi = {10.1111/j.1532-5415.2010.02971.x}, pmid = {20662955}, url = {https://doi.org/10.1111/j.1532-5415.2010.02971.x} } @article{volandes2011-21254815, author = {Volandes, A. E. and Ferguson, L. A. and Davis, A. D. and Hull, N. C. and Green, M. J. and Chang, Y. and Deep, K. and Paasche-Orlow, M. K.}, title = {{Assessing end-of-life preferences for advanced dementia in rural patients using an educational video: a randomized controlled trial}}, journal = {Journal of palliative medicine}, year = {2011}, doi = {10.1089/jpm.2010.0299}, pmid = {21254815}, url = {https://doi.org/10.1089/jpm.2010.0299} } @article{heffernan2019-30475762, author = {Heffernan, M. and Andrews, G. and Fiatarone Singh, M. A. and Valenzuela, M. and Anstey, K. J. and Maeder, A. J. and McNeil, J. and Jorm, L. and others}, title = {{Maintain Your Brain: Protocol of a 3-Year Randomized Controlled Trial of a Personalized Multi-Modal Digital Health Intervention to Prevent Cognitive Decline Among Community Dwelling 55 to 77 Year Olds}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2019}, doi = {10.3233/jad-180572}, pmid = {30475762}, url = {https://doi.org/10.3233/jad-180572} } @article{scullin2022-34786698, author = {Scullin, M. K. and Jones, W. E. and Phenis, R. and Beevers, S. and Rosen, S. and Dinh, K. and Kiselica, A. and Keefe, F. J. and others}, title = {{Using smartphone technology to improve prospective memory functioning: A randomized controlled trial}}, journal = {Journal of the American Geriatrics Society}, year = {2022}, doi = {10.1111/jgs.17551}, pmid = {34786698}, url = {https://doi.org/10.1111/jgs.17551} } @article{wilcock2002-12409683, author = {Wilcock, G. and Möbius, H. J. and Stöffler, A. and {MMM 500 group}}, title = {{A double-blind, placebo-controlled multicentre study of memantine in mild to moderate vascular dementia (MMM500)}}, journal = {International clinical psychopharmacology}, year = {2002}, doi = {10.1097/00004850-200211000-00005}, pmid = {12409683}, url = {https://doi.org/10.1097/00004850-200211000-00005} } @article{wang2022-36150665, author = {Wang, L. and Zhang, J. and Guo, C. and He, J. and Zhang, S. and Wang, Y. and Zhao, Y. and Li, L. and others}, title = {{The efficacy and safety of transcutaneous auricular vagus nerve stimulation in patients with mild cognitive impairment: A double blinded randomized clinical trial}}, journal = {Brain stimulation}, year = {2022}, doi = {10.1016/j.brs.2022.09.003}, pmid = {36150665}, url = {https://doi.org/10.1016/j.brs.2022.09.003} } @article{study2008-18068522, author = {{AD2000 Collaborative Group} and Bentham, P. and Gray, R. and Sellwood, E. and Hills, R. and Crome, P. and Raftery, J.}, title = {{Aspirin in Alzheimer's disease (AD2000): a randomised open-label trial}}, journal = {The Lancet. Neurology}, year = {2008}, doi = {10.1016/s1474-4422(07)70293-4}, pmid = {18068522}, url = {https://doi.org/10.1016/s1474-4422(07)70293-4} } @article{richards2025-39909068, author = {Richards, Kathy Culpepper and Fry, Liam and Lozano, Alicia J and Ji, Wenyan and Morrison, Janet and Britt, Katherine Carroll and Bliwise, Donald L. and Gooneratne, Nalaka Sudheera and others}, title = {{Treatment of Restless Legs Syndrome Improves Agitation and Sleep in Persons with Dementia: A Randomized Trial}}, journal = {Journal of the American Medical Directors Association}, year = {2025}, doi = {10.1016/j.jamda.2025.105485}, pmid = {39909068}, url = {https://doi.org/10.1016/j.jamda.2025.105485} } @article{betz2024-39531391, author = {Betz, M. E. and Portz, J. and Knoepke, C. and Ranney, M. L. and Fischer, S. M. and Peterson, R. A. and Johnson, R. L. and Omeragic, F. and Castaneda, M. and Greenway, E. and Matlock, D.}, title = {{The Effect of the "Safety in Dementia" Online Tool to Assist Decision Making for Caregivers of Persons With Dementia and Access to Firearms: A Randomized Trial}}, journal = {Annals of Internal Medicine}, year = {2024}, doi = {10.7326/ANNALS-24-00763}, pmid = {39531391}, url = {https://doi.org/10.7326/ANNALS-24-00763} } @article{sveinsdottir2025-41380710, author = {Sveinsdottir, V. and Assmus, J. and Schneider, J. and Baker, F. A. and Uçaner, B. and Kreutz, G. and Geretsegger, M. and others}, title = {{Clinical effectiveness of music interventions for dementia and depression in older people (MIDDEL): a multinational, cluster-randomised controlled trial}}, journal = {The Lancet Healthy Longevity}, year = {2025}, doi = {10.1016/j.lanhl.2025.100783}, pmid = {41380710}, url = {https://doi.org/10.1016/j.lanhl.2025.100783} } @article{xu2025-40294622, author = {Xu, Z. and Zhang, D. and Yip, B. H. and Lee, E. K. and Poon, P. K. and Peters, R. and Yang, Z. and Lee, A. T. and Leung, M. K. and Wong, E. L. and others}, title = {{Combined mind-body physical exercise, cognitive training, and nurse-led risk factor modification to enhance cognition among older adults with mild cognitive impairment in primary care: a three-arm randomised controlled trial}}, journal = {The Lancet Healthy Longevity}, year = {2025}, doi = {10.1016/j.lanhl.2025.100706}, pmid = {40294622}, url = {https://doi.org/10.1016/j.lanhl.2025.100706} } @article{mittelman2007-17804831, author = {Mittelman, M. S. and Roth, D. L. and Clay, O. J. and Haley, W. E.}, title = {{Preserving health of Alzheimer caregivers: impact of a spouse caregiver intervention}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2007}, doi = {10.1097/jgp.0b013e31805d858a}, pmid = {17804831}, url = {https://doi.org/10.1097/jgp.0b013e31805d858a} } @article{atri2011-21555634, author = {Atri, A. and O'Brien, J. L. and Sreenivasan, A. and Rastegar, S. and Salisbury, S. and DeLuca, A. N. and O'Keefe, K. M. and LaViolette, P. S. and others}, title = {{Test-retest reliability of memory task functional magnetic resonance imaging in Alzheimer disease clinical trials}}, journal = {Archives of neurology}, year = {2011}, doi = {10.1001/archneurol.2011.94}, pmid = {21555634}, url = {https://doi.org/10.1001/archneurol.2011.94} } @article{dyer2020-31604674, author = {Dyer, A. H. and Murphy, C. and Lawlor, B. and Kennelly, S. P. and {NILVAD Study Group}}, title = {{Cognitive Outcomes of Long-term Benzodiazepine and Related Drug (BDZR) Use in People Living With Mild to Moderate Alzheimer's Disease: Results From NILVAD}}, journal = {Journal of the American Medical Directors Association}, year = {2020}, doi = {10.1016/j.jamda.2019.08.006}, pmid = {31604674}, url = {https://doi.org/10.1016/j.jamda.2019.08.006} } @article{flicker2001-11405971, author = {Flicker, L. and Grimley Evans, G.}, title = {{Piracetam for dementia or cognitive impairment}}, journal = {The Cochrane database of systematic reviews}, year = {2001}, doi = {10.1002/14651858.cd001011}, pmid = {11405971}, url = {https://doi.org/10.1002/14651858.cd001011} } @article{higgins2000-11034695, author = {Higgins, J. P. and Flicker, L.}, title = {{Lecithin for dementia and cognitive impairment}}, journal = {The Cochrane database of systematic reviews}, year = {2000}, doi = {10.1002/14651858.cd001015}, pmid = {11034695}, url = {https://doi.org/10.1002/14651858.cd001015} } @article{mace2024-39571150, author = {Mace, R. A. and Law, M. E. and Cohen, J. E. and Ritchie, C. S. and Okereke, O. I. and Hoeppner, B. B. and Brewer, J. A. and Bartels, S. J. and others}, title = {{A Mindfulness-Based Lifestyle Intervention for Dementia Risk Reduction: Protocol for the My Healthy Brain Feasibility Randomized Controlled Trial}}, journal = {JMIR research protocols}, year = {2024}, doi = {10.2196/64149}, pmid = {39571150}, url = {https://doi.org/10.2196/64149} } @article{saif2020-32665410, author = {Saif, N. and Niotis, K. and Dominguez, M. and Hodes, J. F. and Woodbury, M. and Amini, Y. and Sadek, G. and Scheyer, O. and others}, title = {{Education Research: Online Alzheimer education for high school and college students: A randomized controlled trial}}, journal = {Neurology}, year = {2020}, doi = {10.1212/wnl.0000000000009859}, pmid = {32665410}, url = {https://doi.org/10.1212/wnl.0000000000009859} } @article{anderson2014-25150681, author = {Anderson, N. D. and Damianakis, T. and Kröger, E. and Wagner, L. M. and Dawson, D. R. and Binns, M. A. and Bernstein, S. and Caspi, E. and others}, title = {{The benefits associated with volunteering among seniors: a critical review and recommendations for future research}}, journal = {Psychological bulletin}, year = {2014}, doi = {10.1037/a0037610}, pmid = {25150681}, url = {https://doi.org/10.1037/a0037610} } @article{moyle2018-29563027, author = {Moyle, W. and Jones, C. and Murfield, J. and Thalib, L. and Beattie, E. and Shum, D. and O'Dwyer, S. and Mervin, M. C. and others}, title = {{Effect of a robotic seal on the motor activity and sleep patterns of older people with dementia, as measured by wearable technology: A cluster-randomised controlled trial}}, journal = {Maturitas}, year = {2018}, doi = {10.1016/j.maturitas.2018.01.007}, pmid = {29563027}, url = {https://doi.org/10.1016/j.maturitas.2018.01.007} } @article{molloy2013-22718435, author = {Molloy, D. W. and Standish, T. I. and Zhou, Q. and Guyatt, G. and {DARAD Study Group}}, title = {{A multicenter, blinded, randomized, factorial controlled trial of doxycycline and rifampin for treatment of Alzheimer's disease: the DARAD trial}}, journal = {International journal of geriatric psychiatry}, year = {2013}, doi = {10.1002/gps.3846}, pmid = {22718435}, url = {https://doi.org/10.1002/gps.3846} } @article{rockwood2006-16554498, author = {Rockwood, K. and Fay, S. and Song, X. and MacKnight, C. and Gorman, M.}, title = {{Attainment of treatment goals by people with Alzheimer's disease receiving galantamine: a randomized controlled trial}}, journal = {CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne}, year = {2006}, doi = {10.1503/cmaj.051432}, pmid = {16554498}, url = {https://doi.org/10.1503/cmaj.051432} } @article{howie2012-22717828, author = {Howie, D. W. and Holubowycz, O. T. and Middleton, R. and {Large Articulation Study Group}}, title = {{Large femoral heads decrease the incidence of dislocation after total hip arthroplasty: a randomized controlled trial}}, journal = {The Journal of bone and joint surgery. American volume}, year = {2012}, doi = {10.2106/jbjs.k.00570}, pmid = {22717828}, url = {https://doi.org/10.2106/jbjs.k.00570} } @article{chi2017-27522059, author = {Chi, G. C. and Fitzpatrick, A. L. and Sharma, M. and Jenny, N. S. and Lopez, O. L. and DeKosky, S. T.}, title = {{Inflammatory Biomarkers Predict Domain-Specific Cognitive Decline in Older Adults}}, journal = {The journals of gerontology. Series A, Biological sciences and medical sciences}, year = {2017}, doi = {10.1093/gerona/glw155}, pmid = {27522059}, url = {https://doi.org/10.1093/gerona/glw155} } @article{widmer2015-25447615, author = {Widmer, R. J. and Flammer, A. J. and Lerman, L. O. and Lerman, A.}, title = {{The Mediterranean diet, its components, and cardiovascular disease}}, journal = {The American journal of medicine}, year = {2015}, doi = {10.1016/j.amjmed.2014.10.014}, pmid = {25447615}, url = {https://doi.org/10.1016/j.amjmed.2014.10.014} } @article{belleville2008-17958927, author = {Belleville, S.}, title = {{Cognitive training for persons with mild cognitive impairment}}, journal = {International psychogeriatrics}, year = {2008}, doi = {10.1017/s104161020700631x}, pmid = {17958927}, url = {https://doi.org/10.1017/s104161020700631x} } @article{martinezgonzalez2016-27552476, author = {Martinez-Gonzalez, M. A. and Martin-Calvo, N.}, title = {{Mediterranean diet and life expectancy; beyond olive oil, fruits, and vegetables}}, journal = {Current opinion in clinical nutrition and metabolic care}, year = {2016}, doi = {10.1097/mco.0000000000000316}, pmid = {27552476}, url = {https://doi.org/10.1097/mco.0000000000000316} } @article{schenck2013-23886593, author = {Schenck, C. H. and Montplaisir, J. Y. and Frauscher, B. and Hogl, B. and Gagnon, J. F. and Postuma, R. and Sonka, K. and Jennum, P. and others}, title = {{Rapid eye movement sleep behavior disorder: devising controlled active treatment studies for symptomatic and neuroprotective therapy--a consensus statement from the International Rapid Eye Movement Sleep Behavior Disorder Study Group}}, journal = {Sleep medicine}, year = {2013}, doi = {10.1016/j.sleep.2013.02.016}, pmid = {23886593}, url = {https://doi.org/10.1016/j.sleep.2013.02.016} } @article{stenvall2012-21930310, author = {Stenvall, M. and Berggren, M. and Lundström, M. and Gustafson, Y. and Olofsson, B.}, title = {{A multidisciplinary intervention program improved the outcome after hip fracture for people with dementia--subgroup analyses of a randomized controlled trial}}, journal = {Archives of gerontology and geriatrics}, year = {2012}, doi = {10.1016/j.archger.2011.08.013}, pmid = {21930310}, url = {https://doi.org/10.1016/j.archger.2011.08.013} } @article{barnard2010-20226390, author = {Barnard, K. and Colón-Emeric, C.}, title = {{Extraskeletal effects of vitamin D in older adults: cardiovascular disease, mortality, mood, and cognition}}, journal = {The American journal of geriatric pharmacotherapy}, year = {2010}, doi = {10.1016/j.amjopharm.2010.02.004}, pmid = {20226390}, url = {https://doi.org/10.1016/j.amjopharm.2010.02.004} } @article{sampson2005-15945590, author = {Sampson, E. L. and Ritchie, C. W. and Lai, R. and Raven, P. W. and Blanchard, M. R.}, title = {{A systematic review of the scientific evidence for the efficacy of a palliative care approach in advanced dementia}}, journal = {International psychogeriatrics}, year = {2005}, doi = {10.1017/s1041610205001018}, pmid = {15945590}, url = {https://doi.org/10.1017/s1041610205001018} } @article{hansen2008-18686744, author = {Hansen, R. A. and Gartlehner, G. and Webb, A. P. and Morgan, L. C. and Moore, C. G. and Jonas, D. E.}, title = {{Efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer's disease: a systematic review and meta-analysis}}, journal = {Clinical interventions in aging}, year = {2008}, pmid = {18686744} } @article{cuestatriana2019-31089731, author = {Cuesta-Triana, F. and Verdejo-Bravo, C. and Fernández-Pérez, C. and Martín-Sánchez, F. J.}, title = {{Effect of Milk and Other Dairy Products on the Risk of Frailty, Sarcopenia, and Cognitive Performance Decline in the Elderly: A Systematic Review}}, journal = {Advances in nutrition (Bethesda, Md.)}, year = {2019}, doi = {10.1093/advances/nmy105}, pmid = {31089731}, url = {https://doi.org/10.1093/advances/nmy105} } @article{realdon2016-27887597, author = {Realdon, O. and Rossetto, F. and Nalin, M. and Baroni, I. and Cabinio, M. and Fioravanti, R. and Saibene, F. L. and Alberoni, M. and others}, title = {{Technology-enhanced multi-domain at home continuum of care program with respect to usual care for people with cognitive impairment: the Ability-TelerehABILITation study protocol for a randomized controlled trial}}, journal = {BMC psychiatry}, year = {2016}, doi = {10.1186/s12888-016-1132-y}, pmid = {27887597}, url = {https://doi.org/10.1186/s12888-016-1132-y} } @article{roberts2003-12794385, author = {Roberts, J. S. and LaRusse, S. A. and Katzen, H. and Whitehouse, P. J. and Barber, M. and Post, S. G. and Relkin, N. and Quaid, K. and others}, title = {{Reasons for seeking genetic susceptibility testing among first-degree relatives of people with Alzheimer disease}}, journal = {Alzheimer disease and associated disorders}, year = {2003}, doi = {10.1097/00002093-200304000-00006}, pmid = {12794385}, url = {https://doi.org/10.1097/00002093-200304000-00006} } @article{hartin2016-27485822, author = {Hartin, P. J. and Nugent, C. D. and McClean, S. I. and Cleland, I. and Tschanz, J. T. and Clark, C. J. and Norton, M. C.}, title = {{The Empowering Role of Mobile Apps in Behavior Change Interventions: The Gray Matters Randomized Controlled Trial}}, journal = {JMIR mHealth and uHealth}, year = {2016}, doi = {10.2196/mhealth.4878}, pmid = {27485822}, url = {https://doi.org/10.2196/mhealth.4878} } @article{lam2011-21495078, author = {Lam, L. C. and Chau, R. C. and Wong, B. M. and Fung, A. W. and Lui, V. W. and Tam, C. C. and Leung, G. T. and Kwok, T. C. and others}, title = {{Interim follow-up of a randomized controlled trial comparing Chinese style mind body (Tai Chi) and stretching exercises on cognitive function in subjects at risk of progressive cognitive decline}}, journal = {International journal of geriatric psychiatry}, year = {2011}, doi = {10.1002/gps.2602}, pmid = {21495078}, url = {https://doi.org/10.1002/gps.2602} } @article{stein2011-21694461, author = {Stein, M. S. and Scherer, S. C. and Ladd, K. S. and Harrison, L. C.}, title = {{A randomized controlled trial of high-dose vitamin D2 followed by intranasal insulin in Alzheimer's disease}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2011}, doi = {10.3233/jad-2011-110149}, pmid = {21694461}, url = {https://doi.org/10.3233/jad-2011-110149} } @article{jarvis2007-18090038, author = {Jarvis, Joseph N and Harrison, Thomas Stephen}, title = {{HIV-associated cryptococcal meningitis}}, journal = {AIDS}, year = {2007}, doi = {10.1097/qad.0b013e3282a4a64d}, pmid = {18090038}, url = {https://doi.org/10.1097/qad.0b013e3282a4a64d} } @article{barthelemy2020-32057125, author = {Barthélemy, N. R. and Liu, H. and Lu, W. and Kotzbauer, P. T. and Bateman, R. J. and Lucey, B. P.}, title = {{Sleep Deprivation Affects Tau Phosphorylation in Human Cerebrospinal Fluid}}, journal = {Annals of neurology}, year = {2020}, doi = {10.1002/ana.25702}, pmid = {32057125}, url = {https://doi.org/10.1002/ana.25702} } @article{gonzalez2025-40412418, author = {Gonzalez, L. and Rapaport, P. and Livingston, G. and Amador, S. and Adeleke, M. O. and Barber, J. A. and others}, title = {{Cost-utility analysis of the DREAMS START intervention for people living with dementia and their carers: a within-trial economic evaluation}}, journal = {The Lancet Healthy Longevity}, year = {2025}, doi = {10.1016/j.lanhl.2025.100708}, pmid = {40412418}, url = {https://doi.org/10.1016/j.lanhl.2025.100708} } @article{mittelman2008-18978250, author = {Mittelman, M. S. and Brodaty, H. and Wallen, A. S. and Burns, A.}, title = {{A three-country randomized controlled trial of a psychosocial intervention for caregivers combined with pharmacological treatment for patients with Alzheimer disease: effects on caregiver depression}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2008}, doi = {10.1097/jgp.0b013e3181898095}, pmid = {18978250}, url = {https://doi.org/10.1097/jgp.0b013e3181898095} } @article{stanley2013-23567399, author = {Stanley, M. A. and Calleo, J. and Bush, A. L. and Wilson, N. and Snow, A. L. and Kraus-Schuman, C. and Paukert, A. L. and Petersen, N. J. and others}, title = {{The peaceful mind program: a pilot test of a cognitive-behavioral therapy-based intervention for anxious patients with dementia}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2013}, doi = {10.1016/j.jagp.2013.01.007}, pmid = {23567399}, url = {https://doi.org/10.1016/j.jagp.2013.01.007} } @article{pages2022-35193041, author = {Pagès, A. and Costa, N. and González-Bautista, E. and Mounié, M. and Juillard-Condat, B. and Molinier, L. and Cestac, P. and Rolland, Y. and others}, title = {{Screening for deficits on intrinsic capacity domains and associated healthcare costs}}, journal = {Archives of gerontology and geriatrics}, year = {2022}, doi = {10.1016/j.archger.2022.104654}, pmid = {35193041}, url = {https://doi.org/10.1016/j.archger.2022.104654} } @article{elalili2020-32887591, author = {El Alili, M. and Smaling, H. J. A. and Joling, K. J. and Achterberg, W. P. and Francke, A. L. and Bosmans, J. E. and van der Steen, J. T.}, title = {{Cost-effectiveness of the Namaste care family program for nursing home residents with advanced dementia in comparison with usual care: a cluster-randomized controlled trial}}, journal = {BMC health services research}, year = {2020}, doi = {10.1186/s12913-020-05570-2}, pmid = {32887591}, url = {https://doi.org/10.1186/s12913-020-05570-2} } @article{sekikawa2025-40838083, author = {Sekikawa, A. and Wharton, W. and Murray-Krezan, C. and Wu, M. and Chang, Y. and Snitz, B. E. and Coccari, M. and Yang, S. and others}, title = {{ACE trial design: Equol targeting estrogen receptor-β in vascular and cognitive aging}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2025}, doi = {10.1002/trc2.70144}, pmid = {40838083}, url = {https://doi.org/10.1002/trc2.70144} } @article{liu2025-40876538, author = {Liu, X. and Sacks, F. M. and Beck, T. and Tangney, C. C. and Willett, W. C. and Yassine, H. and Dhana, K. and Aggarwal, N. T. and others}, title = {{Apolipoprotein E ε4-dependent associations between carotenoids and cognitive decline: Findings from the MIND (Mediterranean-DASH Intervention for Neurodegenerative delay) randomized controlled trial}}, journal = {The American journal of clinical nutrition}, year = {2025}, doi = {10.1016/j.ajcnut.2025.08.012}, pmid = {40876538}, url = {https://doi.org/10.1016/j.ajcnut.2025.08.012} } @article{xiao2025-41023309, author = {Xiao, Lily Dongxia and Ullah, Shahid and Yu, Ying and Meyer, Claudia and Chapman, Michael and Chen, Langduo and Tan, Kai Ping and McKechnie, Sue and others}, title = {{Effects of a virtual iSupport Program on carers and people with dementia}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70747}, pmid = {41023309}, url = {https://doi.org/10.1002/alz.70747} } @article{smaling2025-40684251, author = {Smaling, Hanneke J. A. and Joling, Karlijn J. and Rijnhart, Judith J. M. and Twisk, Jos W. R. and Achterberg, Wilco P. and Francke, Anneke L. and van der Steen, Jenny Theodora}, title = {{Namaste Care Family for people with dementia and family−A randomized controlled trial}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70495}, pmid = {40684251}, url = {https://doi.org/10.1002/alz.70495} } @article{gibson2020-33074237, author = {Gibson, G. E. and Luchsinger, J. A. and Cirio, R. and Chen, H. and Franchino-Elder, J. and Hirsch, J. A. and Bettendorff, L. and Chen, Z. and others}, title = {{Benfotiamine and Cognitive Decline in Alzheimer's Disease: Results of a Randomized Placebo-Controlled Phase IIa Clinical Trial}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2020}, doi = {10.3233/jad-200896}, pmid = {33074237}, url = {https://doi.org/10.3233/jad-200896} } @article{demnitzking2026-42328805, author = {Demnitz-King, Harriet and Cooper, Claudia and Poppe, Michaela and Budgett, Jessica and Alberts, Sweedal and Duffy, Larisa and Adeleke, Mariam and Barber, Julie and others}, title = {{Cost utility and cost-effectiveness of the APPLE-Tree programme: Active Prevention in People at risk of dementia through Lifestyle, bEhaviour change and Technology to build REsiliEnce: economic evaluation embedded within a randomised controlled trial}}, journal = {Age and ageing}, year = {2026}, doi = {10.1093/ageing/afag176}, pmid = {42328805}, url = {https://doi.org/10.1093/ageing/afag176} } @article{radke2025-41143334, author = {Rädke, A. and Michalowsky, B. and Kleinke, F. and Platen, M. and Scharf, A. and Pfaff, M. and Buchholz, M. and Mühlichen, F. and Penndorf, P. and Schade, S. and Dombrowski, J. and Lerch, P. E. M. and others}, title = {{Efficacy and cost-effectiveness of extended nursing roles in dementia care: Results of the cluster-randomized trial InDePendent}}, journal = {Alzheimer's \& Dementia}, year = {2025}, doi = {10.1002/alz.70727}, pmid = {41143334}, url = {https://doi.org/10.1002/alz.70727} } @article{karlawish2008-18310554, author = {Karlawish, J. and Kim, S. Y. and Knopman, D. and van Dyck, C. H. and James, B. D. and Marson, D.}, title = {{The views of Alzheimer disease patients and their study partners on proxy consent for clinical trial enrollment}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2008}, doi = {10.1097/jgp.0b013e318162992d}, pmid = {18310554}, url = {https://doi.org/10.1097/jgp.0b013e318162992d} } @article{prizer2020-32736164, author = {Prizer, L. P. and Kluger, B. M. and Sillau, S. and Katz, M. and Galifianakis, N. B. and Miyasaki, J. M.}, title = {{The presence of a caregiver is associated with patient outcomes in patients with Parkinson's disease and atypical parkinsonisms}}, journal = {Parkinsonism \& related disorders}, year = {2020}, doi = {10.1016/j.parkreldis.2020.07.003}, pmid = {32736164}, url = {https://doi.org/10.1016/j.parkreldis.2020.07.003} } @article{kim2011-21975207, author = {Kim, S. Y. and Kim, H. M. and Knopman, D. S. and De Vries, R. and Damschroder, L. and Appelbaum, P. S.}, title = {{Effect of public deliberation on attitudes toward surrogate consent for dementia research}}, journal = {Neurology}, year = {2011}, doi = {10.1212/wnl.0b013e31823648cb}, pmid = {21975207}, url = {https://doi.org/10.1212/wnl.0b013e31823648cb} } @article{deheus2019-31088188, author = {de Heus, R. A. A. and Donders, R. and Santoso, A. M. M. and Olde Rikkert, M. G. M. and Lawlor, B. A. and Claassen, J. A. H. R. and {Nilvad Study Group}}, title = {{Blood Pressure Lowering With Nilvadipine in Patients With Mild-to-Moderate Alzheimer Disease Does Not Increase the Prevalence of Orthostatic Hypotension}}, journal = {Journal of the American Heart Association}, year = {2019}, doi = {10.1161/jaha.119.011938}, pmid = {31088188}, url = {https://doi.org/10.1161/jaha.119.011938} } @article{wang2025-40552996, author = {Wang, T. and Yan, S. and Shan, Y. and Xue, H. and Xing, Y. and Bi, S. and Chen, Z. and Xi, H. and others}, title = {{Modulation of Cortical and Hippocampal Functional MRI Connectivity Following Transcranial Alternating Current Stimulation in Mild Alzheimer Disease}}, journal = {Radiology}, year = {2025}, doi = {10.1148/radiol.241463}, pmid = {40552996}, url = {https://doi.org/10.1148/radiol.241463} } @article{lilamand2018-30207586, author = {Lilamand, M. and Cesari, M. and Cantet, C. and Payoux, P. and Andrieu, S. and Vellas, B. and {the MAPT/DSA study group}}, title = {{Relationship Between Brain Amyloid Deposition and Instrumental Activities of Daily Living in Older Adults: A Longitudinal Study from the Multidomain Alzheimer Prevention Trial}}, journal = {Journal of the American Geriatrics Society}, year = {2018}, doi = {10.1111/jgs.15497}, pmid = {30207586}, url = {https://doi.org/10.1111/jgs.15497} } @article{vreugdenhil2012-21564154, author = {Vreugdenhil, A. and Cannell, J. and Davies, A. and Razay, G.}, title = {{A community-based exercise programme to improve functional ability in people with Alzheimer's disease: a randomized controlled trial}}, journal = {Scandinavian journal of caring sciences}, year = {2012}, doi = {10.1111/j.1471-6712.2011.00895.x}, pmid = {21564154}, url = {https://doi.org/10.1111/j.1471-6712.2011.00895.x} } @article{mcbain2019-31485970, author = {McBain, R. K. and Sousa, J. L. and Rose, A. J. and Baxi, S. M. and Faherty, L. J. and Taplin, C. and Chappel, A. and Fischer, S. H.}, title = {{Impact of Project ECHO Models of Medical Tele-Education: a Systematic Review}}, journal = {Journal of general internal medicine}, year = {2019}, doi = {10.1007/s11606-019-05291-1}, pmid = {31485970}, url = {https://doi.org/10.1007/s11606-019-05291-1} } @article{vandewinckel2004-15137556, author = {Van de Winckel, A. and Feys, H. and De Weerdt, W. and Dom, R.}, title = {{Cognitive and behavioural effects of music-based exercises in patients with dementia}}, journal = {Clinical rehabilitation}, year = {2004}, doi = {10.1191/0269215504cr750oa}, pmid = {15137556}, url = {https://doi.org/10.1191/0269215504cr750oa} } @article{ye2025-40324768, author = {Ye, Mengfei and Liu, Zheng and Xie, Weigen and Shou, Mengna and Wang, S J and Lin, Xuebing and Xu, Yan and Yao, Miner and others}, title = {{Implementation of Telemedicine for Patients With Dementia and Their Caregivers: Scoping Review}}, journal = {Journal of Medical Internet Research}, year = {2025}, doi = {10.2196/65667}, pmid = {40324768}, url = {https://doi.org/10.2196/65667} } @article{fowler2026-42008257, author = {Fowler, N. R. and Perkins, A. J. and Gao, S. and Bakas, T. and Head, K. J. and Higbie, A. and Baucco, C. and Callahan, C. M. and Williams-Farrelly, M. M. and Boustani, M. A.}, title = {{Benefits and Harms of Dementia Screening for Family Members of Older Adults: A Randomized Clinical Trial}}, journal = {JAMA Internal Medicine}, year = {2026}, doi = {10.1001/jamainternmed.2026.0844}, pmid = {42008257}, url = {https://doi.org/10.1001/jamainternmed.2026.0844} } @article{cheng2026-41644333, author = {Cheng, Sheung-Tak and Ng, Peter H F}, title = {{Intervention Without Borders - an Automated Self-Guided AI-Enhanced Psychoeducation Intervention for Dementia Caregivers: Parallel-Group Randomized Waitlist-Controlled Trial}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2026}, doi = {10.1016/j.jagp.2026.01.001}, pmid = {41644333}, url = {https://doi.org/10.1016/j.jagp.2026.01.001} } @article{han2026-42233272, author = {Han, Hae-Ra and Perrin, Nancy and Yun, Ji-Young and Min, Deborah and Kwon, Simona C and Joo, Jinhui and Cho, Ji-Young and Kim, Sara and others}, title = {{Efficacy of a language-concordant community health worker intervention to improve community-to-clinic linkage for dementia care: results of the randomized trial PLAN}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71541}, pmid = {42233272}, url = {https://doi.org/10.1002/alz.71541} } @article{lin2015-26632742, author = {Lin, F. C. and Chuang, Y. S. and Hsieh, H. M. and Lee, T. C. and Chiu, K. F. and Liu, C. K. and Wu, M. T.}, title = {{Early Statin Use and the Progression of Alzheimer Disease: A Total Population-Based Case-Control Study}}, journal = {Medicine}, year = {2015}, doi = {10.1097/md.0000000000002143}, pmid = {26632742}, url = {https://doi.org/10.1097/md.0000000000002143} } @article{duggleby2019-31625947, author = {Duggleby, W. and Ploeg, J. and McAiney, C. and Fisher, K. and Jovel Ruiz, K. and Ghosh, S. and Peacock, S. and Markle-Reid, M. and others}, title = {{A Comparison of Users and Nonusers of a Web-Based Intervention for Carers of Older Persons With Alzheimer Disease and Related Dementias: Mixed Methods Secondary Analysis}}, journal = {Journal of medical Internet research}, year = {2019}, doi = {10.2196/14254}, pmid = {31625947}, url = {https://doi.org/10.2196/14254} } @article{woodworth2023-37831492, author = {Woodworth, E. C. and Briskin, E. A. and Plys, E. and Macklin, E. and Tatar, R. G. and Huberty, J. and Vranceanu, A. M.}, title = {{Mindfulness-Based App to Reduce Stress in Caregivers of Persons With Alzheimer Disease and Related Dementias: Protocol for a Single-Blind Feasibility Proof-of-Concept Randomized Controlled Trial}}, journal = {JMIR research protocols}, year = {2023}, doi = {10.2196/50108}, pmid = {37831492}, url = {https://doi.org/10.2196/50108} } @article{gentry2019-30416025, author = {Gentry, M. T. and Lapid, M. I. and Rummans, T. A.}, title = {{Geriatric Telepsychiatry: Systematic Review and Policy Considerations}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2019}, doi = {10.1016/j.jagp.2018.10.009}, pmid = {30416025}, url = {https://doi.org/10.1016/j.jagp.2018.10.009} } @article{rait2005-15863409, author = {Rait, G. and Fletcher, A. and Smeeth, L. and Brayne, C. and Stirling, S. and Nunes, M. and Breeze, E. and Ng, E. S. and others}, title = {{Prevalence of cognitive impairment: results from the MRC trial of assessment and management of older people in the community}}, journal = {Age and ageing}, year = {2005}, doi = {10.1093/ageing/afi039}, pmid = {15863409}, url = {https://doi.org/10.1093/ageing/afi039} } @article{whitfield2025-41267582, author = {Whitfield, Elenyd M and Cooper, Claudia and Demnitz‐King, Harriet and Zabihi, Sedigheh and Barber, Julie and Adeleke, Mariam Olaide and Morse, Rachel M. and Ahmed, A Karim and others}, title = {{Process evaluation of APPLE-Tree (active prevention in people at risk of dementia through lifestyle behaviour change and technology to build resilience): dementia prevention study focused on health and lifestyle changes}}, journal = {BJPsych Open}, year = {2025}, doi = {10.1192/bjo.2025.10874}, pmid = {41267582}, url = {https://doi.org/10.1192/bjo.2025.10874} } @article{yuan2025-40925598, author = {Yuan, Shasha and Zhang, Jingbin and Wang, Zheng and Wang, Huali and Xia, Mengfen}, title = {{Supporting Informal Dementia Caregivers Through an iSupport Web-Based Primary Health Care Intervention: Hybrid Effectiveness-Implementation Mixed Methods Study}}, journal = {Journal of Medical Internet Research}, year = {2025}, doi = {10.2196/77688}, pmid = {40925598}, url = {https://doi.org/10.2196/77688} } @article{amador2025-40116618, author = {Amador, Sarah and Livingston, Gill and Adeleke, Mariam Olaide and Barber, Julie and Webster, Lucy Anne and Yuan, Hang and Banerjee, Sube and Bhojwani, Ankita and others}, title = {{Process evaluation in a randomised controlled trial of DREAMS-START (dementia related manual for sleep; strategies for relatives) for sleep disturbance in people with dementia and their carers}}, journal = {Age and Ageing}, year = {2025}, doi = {10.1093/ageing/afaf053}, pmid = {40116618}, url = {https://doi.org/10.1093/ageing/afaf053} } @article{donath2025-40082869, author = {Donath, Carolin and Keck, Antonia and Graessel, Elmar and Altona, Janissa and Stiefler, Susanne and Misonow, Julia and Guenay, Serhat and Wolf‐Ostermann, Karin and others}, title = {{Urban-rural differences in the health care of people living with dementia and mild cognitive impairment in shared-housing arrangements in Germany – have inequities in urban vs. rural locations been overcome?}}, journal = {BMC Health Services Research}, year = {2025}, doi = {10.1186/s12913-025-12508-z}, pmid = {40082869}, url = {https://doi.org/10.1186/s12913-025-12508-z} } @article{sugimoto2025-40065916, author = {Sugimoto, Taiki and Uchida, Kazuaki and Sato, Kenji and Yokoyama, Yoko and Onoyama, Ayaka and Fujita, Kosuke and Kuroda, Yujiro and Wakayama, Satomu and others}, title = {{Factors associated with adherence to tablet‐based cognitive training: J‐MINT study}}, journal = {Alzheimer s \& Dementia Translational Research \& Clinical Interventions}, year = {2025}, doi = {10.1002/trc2.70062}, pmid = {40065916}, url = {https://doi.org/10.1002/trc2.70062} } @article{beyer2025-40378769, author = {Beyer, Frauke and Kleine, Lukas and Zülke, Andrea E. and Luppa, Melanie and Mildner, Toralf and Gensichen, Jochen Stefan and Frese, Thomas and Czock, David and others}, title = {{Exploring the effect of multi-modal intervention against cognitive decline on atrophy and small vessel disease imaging markers in the AgeWell.de imaging study}}, journal = {NeuroImage Clinical}, year = {2025}, doi = {10.1016/j.nicl.2025.103796}, pmid = {40378769}, url = {https://doi.org/10.1016/j.nicl.2025.103796} } @article{munro2025-41173649, author = {Munro, Cindy L. and Liang, Zhan and Elias, Maya N. and Ji, Ming and Chen, Xusheng and Kip, Paula L. and Greengold, Judy and Ely, Eugene Wesley and others}, title = {{Delirium Reduction via Scripted Family Voice Recordings in Critically Ill Patients Receiving Mechanical Ventilation}}, journal = {American Journal of Critical Care}, year = {2025}, doi = {10.4037/ajcc2025486}, pmid = {41173649}, url = {https://doi.org/10.4037/ajcc2025486} } @article{jiaming2023-37227755, author = {Jiaming, Liang and Aranda Maria, P.}, title = {{The Use of Telehealth Among People Living With Dementia-Caregiver Dyads During the COVID-19 Pandemic: Scoping Review}}, journal = {Journal of medical Internet research}, year = {2023}, doi = {10.2196/45045}, pmid = {37227755}, url = {https://doi.org/10.2196/45045} } @article{stevens2025-41085219, author = {Stevens, A. B. and Cho, J. and Birchfield, T. and Reese, J. and Han, G. and Thorud, J. L. and Ory, M. G.}, title = {{A randomized trial of two online platforms for dementia family caregivers: GamePlan4Care and Resources4Care}}, journal = {Alzheimer's \& Dementia}, year = {2025}, doi = {10.1002/alz.70690}, pmid = {41085219}, url = {https://doi.org/10.1002/alz.70690} } @article{albertyn2025-40479610, author = {Albertyn, C. P. and Guu, T. W. and Chu, P. and Creese, B. and Young, A. and Velayudhan, L. and Bhattacharyya, S. and Jafari, H. and Kaur, S. and Kandangwa, P. and others}, title = {{Sativex (nabiximols) for the treatment of Agitation \& Aggression in Alzheimer's dementia in UK nursing homes: a randomised, double-blind, placebo-controlled feasibility trial}}, journal = {Age and Ageing}, year = {2025}, doi = {10.1093/ageing/afaf149}, pmid = {40479610}, url = {https://doi.org/10.1093/ageing/afaf149} } @article{brijnath2026-41719424, author = {Brijnath, Bianca and Dang, Thu Ha and Enticott, Joanne and Tian, Yuan and Markusevska, Simona and Antoniades, Josefine and Nguyen, Tuan Anh and Gilbert, Andrew and others}, title = {{Evaluating the effects of the World Health Organisation's online intervention 'iSupport lite' to reduce burden in multilingual dementia carers: results from the Australian Draw-Care randomised clinical trial}}, journal = {Age and ageing}, year = {2026}, doi = {10.1093/ageing/afag030}, pmid = {41719424}, url = {https://doi.org/10.1093/ageing/afag030} } @article{cheng2014-24688081, author = {Cheng, S. T. and Lau, R. W. and Mak, E. P. and Ng, N. S. and Lam, L. C.}, title = {{Benefit-finding intervention for Alzheimer caregivers: conceptual framework, implementation issues, and preliminary efficacy}}, journal = {The Gerontologist}, year = {2014}, doi = {10.1093/geront/gnu018}, pmid = {24688081}, url = {https://doi.org/10.1093/geront/gnu018} } @article{brodaty2009-19705519, author = {Brodaty, H. and Mittelman, M. and Gibson, L. and Seeher, K. and Burns, A.}, title = {{The effects of counseling spouse caregivers of people with Alzheimer disease taking donepezil and of country of residence on rates of admission to nursing homes and mortality}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2009}, doi = {10.1097/jgp.0b013e3181a65187}, pmid = {19705519}, url = {https://doi.org/10.1097/jgp.0b013e3181a65187} } @article{modrego2010-19874395, author = {Modrego, P. J. and Fayed, N. and Errea, J. M. and Rios, C. and Pina, M. A. and Sarasa, M.}, title = {{Memantine versus donepezil in mild to moderate Alzheimer's disease: a randomized trial with magnetic resonance spectroscopy}}, journal = {European journal of neurology}, year = {2010}, doi = {10.1111/j.1468-1331.2009.02816.x}, pmid = {19874395}, url = {https://doi.org/10.1111/j.1468-1331.2009.02816.x} } @article{vandermaaden2016-27515720, author = {van der Maaden, T. and de Vet, H. C. and Achterberg, W. P. and Boersma, F. and Schols, J. M. and Mehr, D. R. and Galindo-Garre, F. and Hertogh, C. M. and others}, title = {{Improving comfort in people with dementia and pneumonia: a cluster randomized trial}}, journal = {BMC medicine}, year = {2016}, doi = {10.1186/s12916-016-0663-x}, pmid = {27515720}, url = {https://doi.org/10.1186/s12916-016-0663-x} } @article{okumiya1996-8617907, author = {Okumiya, K. and Matsubayashi, K. and Wada, T. and Kimura, S. and Doi, Y. and Ozawa, T.}, title = {{Effects of exercise on neurobehavioral function in community-dwelling older people more than 75 years of age}}, journal = {Journal of the American Geriatrics Society}, year = {1996}, doi = {10.1111/j.1532-5415.1996.tb01444.x}, pmid = {8617907}, url = {https://doi.org/10.1111/j.1532-5415.1996.tb01444.x} } @article{mamas2025-40980721, author = {Mamas, Mamas A. and Bays, Harold Edward and Li, Runjia and Upadhyay, Navneet and Irani, Tanya and Şenyücel, Çağrı and Dunn, Julia P. and Liu‐Seifert, Hong}, title = {{Tirzepatide compared with semaglutide and 10-year cardiovascular disease risk reduction in obesity: post-hoc analysis of the SURMOUNT-5 trial}}, journal = {European Heart Journal Open}, year = {2025}, doi = {10.1093/ehjopen/oeaf117}, pmid = {40980721}, url = {https://doi.org/10.1093/ehjopen/oeaf117} } @article{schneider2025-40559671, author = {Schneider, Andy and Leite, Luciano Bernardes and Teixeira, José E. and Forte, Pedro Miguel and Barbosa, Tiago M. and Monteiro, António M.}, title = {{Multicomponent Exercise and Functional Fitness: Strategies for Fall Prevention in Aging Women}}, journal = {Sports}, year = {2025}, doi = {10.3390/sports13060159}, pmid = {40559671}, url = {https://doi.org/10.3390/sports13060159} } @article{berge2025-40042468, author = {Berge, Line Iden and Angeles, Renira C. and Gedde, Marie Hidle and Fæø, Stein Erik and Mannseth, Janne and Vislapuu, Maarja and Puaschitz, Nathalie Genevieve and Hillestad, Eirin and others}, title = {{Burden and care time for dementia caregivers in the LIVE@Home.Path trial}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.14622}, pmid = {40042468}, url = {https://doi.org/10.1002/alz.14622} } @article{han2025-40163859, author = {Han, Areum and Oster, Robert A. and Yuen, Hon K. and Jenkins, Jeremy and Hawkins, Jessica and Edwards, Lauren}, title = {{Videoconference-Delivered Acceptance and Commitment Therapy for Family Caregivers of People With Dementia: Pilot Randomized Controlled Trial}}, journal = {JMIR Formative Research}, year = {2025}, doi = {10.2196/67545}, pmid = {40163859}, url = {https://doi.org/10.2196/67545} } @article{huang2025-40316979, author = {Huang, Chenshan and Yan, Yuanjiao and Tam, Wilson and Sun, Wenqian and Ye, Yu and Wang, Nafang and Shi, Yanhong and Zhu, Ziping and others}, title = {{Effects of an integrated social-art intervention on cognitive and psychosocial outcomes among older adults with mild cognitive impairment in nursing homes: a mixed methods study}}, journal = {BMC Medicine}, year = {2025}, doi = {10.1186/s12916-025-04085-z}, pmid = {40316979}, url = {https://doi.org/10.1186/s12916-025-04085-z} } @article{amabili2025-40896828, author = {Amabili, Giulio and Maranesi, Elvira and Margaritini, Arianna and Bonfigli, Anna Rita and Felici, Elisa and Barbarossa, Federico and Benadduci, Marco and Gosetto, Laëtitia and others}, title = {{Managing Cognitive Decline Through a Social Robot–Based Intervention: Protocol for the engAGE Proof of Concept and Randomized Controlled Trial}}, journal = {JMIR Research Protocols}, year = {2025}, doi = {10.2196/67601}, pmid = {40896828}, url = {https://doi.org/10.2196/67601} } @article{tainta2025-40589624, author = {Tainta, Mikel and Ecay‐Torres, Mirian and Barandiarán, Myriam and Estanga, Ainara and López, Carolina and Altuna, Miren and Iriondo, Ane and Saldias, Jon and others}, title = {{CITA GO-ON study. A community based multidomain lifestyle intervention to prevent cognitive decline. Protocol design and recruitment process}}, journal = {Frontiers in Aging Neuroscience}, year = {2025}, doi = {10.3389/fnagi.2025.1539711}, pmid = {40589624}, url = {https://doi.org/10.3389/fnagi.2025.1539711} } @article{parkerlauren2021-34647482, author = {Parker Lauren, J. and Katherine, Marx and Gaugler Joseph, E. and Gitlin Laura, N.}, title = {{Implications of the COVID-19 Pandemic on Adult Day Services and the Families They Serve}}, journal = {American journal of Alzheimer's disease and other dementias}, year = {2021}, doi = {10.1177/15333175211050152}, pmid = {34647482}, url = {https://doi.org/10.1177/15333175211050152} } @article{pardini2015-25592742, author = {Pardini, M. and Serrati, C. and Guida, S. and Mattei, C. and Abate, L. and Massucco, D. and Sassos, D. and Amore, M. and others}, title = {{Souvenaid reduces behavioral deficits and improves social cognition skills in frontotemporal dementia: a proof-of-concept study}}, journal = {Neuro-degenerative diseases}, year = {2015}, doi = {10.1159/000369811}, pmid = {25592742}, url = {https://doi.org/10.1159/000369811} } @article{gouilly2025-41287056, author = {Gouilly, D. and Da-Costa, A. and Vrillon, A. and Pistono, A. and Goubeaud, M. and Bertrand, E. and Germain, J. and Ainaoui, N. and others}, title = {{Inhibition of p38α MAPK increases short-term astrocyte reactivity: the exploratory VIP trial in early Alzheimer's disease}}, journal = {Journal of neuroinflammation}, year = {2025}, doi = {10.1186/s12974-025-03625-x}, pmid = {41287056}, url = {https://doi.org/10.1186/s12974-025-03625-x} } @article{lavretsky2010-20104071, author = {Lavretsky, H. and Siddarth, P. and Irwin, M. R.}, title = {{Improving depression and enhancing resilience in family dementia caregivers: a pilot randomized placebo-controlled trial of escitalopram}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2010}, doi = {10.1097/jgp.0b013e3181beab1e}, pmid = {20104071}, url = {https://doi.org/10.1097/jgp.0b013e3181beab1e} } @article{regan2017-28034509, author = {Regan, B. and Wells, Y. and Farrow, M. and O'Halloran, P. and Workman, B.}, title = {{MAXCOG-Maximizing Cognition: A Randomized Controlled Trial of the Efficacy of Goal-Oriented Cognitive Rehabilitation for People with Mild Cognitive Impairment and Early Alzheimer Disease}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2017}, doi = {10.1016/j.jagp.2016.11.008}, pmid = {28034509}, url = {https://doi.org/10.1016/j.jagp.2016.11.008} } @article{baumel2021-33368017, author = {Baumel, B. S. and Doraiswamy, P. M. and Sabbagh, M. and Wurtman, R.}, title = {{Potential Neuroregenerative and Neuroprotective Effects of Uridine/Choline-Enriched Multinutrient Dietary Intervention for Mild Cognitive Impairment: A Narrative Review}}, journal = {Neurology and therapy}, year = {2021}, doi = {10.1007/s40120-020-00227-y}, pmid = {33368017}, url = {https://doi.org/10.1007/s40120-020-00227-y} } @article{papatsimpas2023-37509042, author = {Papatsimpas, V. and Vrouva, S. and Papathanasiou, G. and Papadopoulou, M. and Bouzineki, C. and Kanellopoulou, S. and Moutafi, D. and Bakalidou, D.}, title = {{Does Therapeutic Exercise Support Improvement in Cognitive Function and Instrumental Activities of Daily Living in Patients with Mild Alzheimer's Disease? A Randomized Controlled Trial}}, journal = {Brain sciences}, year = {2023}, doi = {10.3390/brainsci13071112}, pmid = {37509042}, url = {https://doi.org/10.3390/brainsci13071112} } @article{nguyen2018-30334942, author = {Nguyen, T. A. and Nguyen, H. and Pham, T. and Nguyen, T. H. and Hinton, L.}, title = {{A cluster randomized controlled trial to test the feasibility and preliminary effectiveness of a family dementia caregiver intervention in Vietnam: The REACH VN study protocol}}, journal = {Medicine}, year = {2018}, doi = {10.1097/md.0000000000012553}, pmid = {30334942}, url = {https://doi.org/10.1097/md.0000000000012553} } @article{cheng2022-34843329, author = {Cheng, S. T. and Chan, W. C. and Fung, H. H. and Lam, L. C. W.}, title = {{Self-efficacy in controlling upsetting thoughts, but not positive gains, mediates the effects of benefit-finding group intervention for Alzheimer family caregivers}}, journal = {Psychology and aging}, year = {2022}, doi = {10.1037/pag0000654}, pmid = {34843329}, url = {https://doi.org/10.1037/pag0000654} } @article{gonzalezbautista2023-35226732, author = {Gonzalez-Bautista, E. and de Souto Barreto, P. and Salinas-Rodriguez, A. and Manrique-Espinoza, B. and Sourdet, S. and Rolland, Y. and Rodríguez-Mañas, L. and Andrieu, S. and others}, title = {{Development and Validation of a Cutoff for the Chair Stand Test as a Screening for Mobility Impairment in the Context of the Integrated Care for Older People Program}}, journal = {The journals of gerontology. Series A, Biological sciences and medical sciences}, year = {2023}, doi = {10.1093/gerona/glac055}, pmid = {35226732}, url = {https://doi.org/10.1093/gerona/glac055} } @article{duggleby2017-28806917, author = {Duggleby, W. and Ploeg, J. and McAiney, C. and Fisher, K. and Swindle, J. and Chambers, T. and Ghosh, S. and Peacock, S. and others}, title = {{Study protocol: pragmatic randomized control trial of an internet-based intervention (My tools 4 care) for family carers}}, journal = {BMC geriatrics}, year = {2017}, doi = {10.1186/s12877-017-0581-6}, pmid = {28806917}, url = {https://doi.org/10.1186/s12877-017-0581-6} } @article{mccarthy2023-36719721, author = {McCarthy, V. and Portz, J. and Fischer, S. M. and Greenway, E. and Johnson, R. L. and Knoepke, C. E. and Matlock, D. D. and Omeragic, F. and others}, title = {{A Web-Based Decision Aid for Caregivers of Persons With Dementia With Firearm Access (Safe at Home Study): Protocol for a Randomized Controlled Trial}}, journal = {JMIR research protocols}, year = {2023}, doi = {10.2196/43702}, pmid = {36719721}, url = {https://doi.org/10.2196/43702} } @article{travis2024-39392675, author = {Travis, A. and O'Donnell, A. and Giraldo-Santiago, N. and Stone, S. M. and Torres, D. and Adler, SR. and Vranceanu, A. M. and Ritchie, C. S.}, title = {{Intervention for the Management of Neuropsychiatric Symptoms to Reduce Caregiver Stress: Protocol for the Mindful and Self-Compassion Care Intervention for Caregivers of Persons Living With Dementia}}, journal = {JMIR research protocols}, year = {2024}, doi = {10.2196/58356}, pmid = {39392675}, url = {https://doi.org/10.2196/58356} } @article{moletbenhamou2022-36097005, author = {Molet-Benhamou, L. and Giudici, K. V. and de Souto Barreto, P. and Cantet, C. and Rolland, Y. and {MAPT/DSA group}}, title = {{Association between urate-lowering therapies and cognitive decline in community-dwelling older adults}}, journal = {Scientific reports}, year = {2022}, doi = {10.1038/s41598-022-17808-6}, pmid = {36097005}, url = {https://doi.org/10.1038/s41598-022-17808-6} } @article{ottman2026-42712082, author = {Ottman, Ruth and Wetmore, John Brandon and Leu, Cheng-Shiun and Uhlmann, Wendy R. and Goldman, Jill and Rodriguez, Sophia and Caro, Daniela Diaz and Caban, Maria L. and others}, title = {{Psychological impacts of APOE genotype disclosure among Latinos in New York City: a randomized controlled trial}}, journal = {Alzheimer s \& Dementia}, year = {2026}, doi = {10.1002/alz.71796}, pmid = {42712082}, url = {https://doi.org/10.1002/alz.71796} } @article{flanders2026-42149605, author = {Flanders, Michael D. and Caunca, Michelle and La Joie, Renaud and Schneider, Lon S. S. and Ackley, Sarah F.}, title = {{Methodological Considerations for Quantile Aggregation in Alzheimer Disease Trials}}, journal = {JAMA Neurology}, year = {2026}, doi = {10.1001/jamaneurol.2026.1240}, pmid = {42149605}, url = {https://doi.org/10.1001/jamaneurol.2026.1240} } @article{nguyen2025-41000210, author = {Nguyen, Tran To Tran and Vu, Lan Duong Tuyet and Truong, Khoa Tri and Nguyen, Tuan Chau and Thai, Truc Thanh and Schofield, Penelope E. and Nguyen, Tuan Anh and Than, The Ha Ngoc and others}, title = {{Smartphone App-Based Psychoeducation for Caregivers of People with Dementia in Vietnam: A Pilot Randomized Controlled Trial}}, journal = {Clinical Interventions in Aging}, year = {2025}, doi = {10.2147/cia.s551994}, pmid = {41000210}, url = {https://doi.org/10.2147/cia.s551994} } @article{nguyen2025-41158517, author = {Nguyen, Tran To Tran and Vu, Lan Duong Tuyet and Nguyen, Tuan Anh and Truong, Khoa Tri and Thai, Truc Thanh and Than, The Ha Ngoc and Nguyen, Huan Thanh}, title = {{Mobile App Psychoeducation for Dementia Caregivers In Vietnam: A Randomized Controlled Trial}}, journal = {Journal of Multidisciplinary Healthcare}, year = {2025}, doi = {10.2147/jmdh.s557573}, pmid = {41158517}, url = {https://doi.org/10.2147/jmdh.s557573} } @article{gonzalezmoreno2025-39840773, author = {González-Moreno, Jesús and Satorres, Encarnación and Meléndez, Juan C. and Soria-Urios, Gema}, title = {{Comparing Traditional and Technology-Based Methods for Executive Function and Attention Training in Moderate Alzheimer's Dementia}}, journal = {Psicothema}, year = {2025}, doi = {10.70478/psicothema.2025.37.05}, pmid = {39840773}, url = {https://doi.org/10.70478/psicothema.2025.37.05} } @article{cherbuin2026-42098784, author = {Cherbuin, Nicolas and Northey, Joseph M. and Walsh, Erin I. and Burns, Richard A. and Speer, Hollie and Lawlis, Nicholas and Namsrai, Tergel and Scott, Amanda and others}, title = {{A randomised controlled trial of physical activity and cognitive training in older adults: the PhABHeaD study}}, journal = {Trials}, year = {2026}, doi = {10.1186/s13063-026-09681-9}, pmid = {42098784}, url = {https://doi.org/10.1186/s13063-026-09681-9} } @article{jehu2025-39950072, author = {Jehu, Deborah A. and Bek, Judith and Bennett, Crystal G. and Hackney, Madeleine E.}, title = {{Group and partnered dance for people living with dementia: an overview of intervention design and measurement considerations}}, journal = {Frontiers in Psychology}, year = {2025}, doi = {10.3389/fpsyg.2025.1500688}, pmid = {39950072}, url = {https://doi.org/10.3389/fpsyg.2025.1500688} } @article{guo2013-23314060, author = {Guo, L. H. and Alexopoulos, P. and Wagenpfeil, S. and Kurz, A. and Perneczky, R. and {Alzheimer’s Disease Neuroimaging Initiative}}, title = {{Plasma proteomics for the identification of Alzheimer disease}}, journal = {Alzheimer disease and associated disorders}, year = {2013}, doi = {10.1097/wad.0b013e31827b60d2}, pmid = {23314060}, url = {https://doi.org/10.1097/wad.0b013e31827b60d2} } @article{karima2023-37248896, author = {Karima, S. and Aghamollaii, V. and Mahmoodi Baram, S. and Balenci, L. and Lanctôt, K. L. and Kiss, A. and Tafakhori, A. and Mahdavi, M. and others}, title = {{Boswellic Acids Improve Clinical Cognitive Scores and Reduce Systemic Inflammation in Patients with Mild to Moderate Alzheimer's Disease}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2023}, doi = {10.3233/jad-221026}, pmid = {37248896}, url = {https://doi.org/10.3233/jad-221026} } @article{bianchi2026-42613673, author = {Bianchi, Federica and Broers, Barbara and Desmeules, Jules Alexandre and Langlois, Angeline and Wampfler, James and Curtin, François and Pautex, Sophie}, title = {{A randomised, double-blind, placebo-controlled crossover trial on cannabinoid-based medication for behavioural disorders in old patients with severe dementia: the study results}}, journal = {Age and ageing}, year = {2026}, doi = {10.1093/ageing/afag239}, pmid = {42613673}, url = {https://doi.org/10.1093/ageing/afag239} } @article{rolland2010-20176294, author = {Rolland, Y. and Abellan van Kan, G. and Vellas, B.}, title = {{Healthy brain aging: role of exercise and physical activity}}, journal = {Clinics in geriatric medicine}, year = {2010}, doi = {10.1016/j.cger.2009.11.002}, pmid = {20176294}, url = {https://doi.org/10.1016/j.cger.2009.11.002} } @article{nakanishi2018-28857263, author = {Nakanishi, M. and Endo, K. and Hirooka, K. and Granvik, E. and Minthon, L. and Nägga, K. and Nishida, A.}, title = {{Psychosocial behaviour management programme for home-dwelling people with dementia: A cluster-randomized controlled trial}}, journal = {International journal of geriatric psychiatry}, year = {2018}, doi = {10.1002/gps.4784}, pmid = {28857263}, url = {https://doi.org/10.1002/gps.4784} } @article{cooper2014-24888381, author = {Cooper, S. A. and Caslake, M. and Evans, J. and Hassiotis, A. and Jahoda, A. and McConnachie, A. and Morrison, J. and Ring, H. and others}, title = {{Toward onset prevention of cognitive decline in adults with Down syndrome (the TOP-COG study): study protocol for a randomized controlled trial}}, journal = {Trials}, year = {2014}, doi = {10.1186/1745-6215-15-202}, pmid = {24888381}, url = {https://doi.org/10.1186/1745-6215-15-202} } @article{nadeau2024-38484213, author = {Nadeau, S. E.}, title = {{Lecanemab Questions}}, journal = {Neurology}, year = {2024}, doi = {10.1212/wnl.0000000000209320}, pmid = {38484213}, url = {https://doi.org/10.1212/wnl.0000000000209320} } @article{baker2001-11317951, author = {Baker, R. and Bell, S. and Baker, E. and Gibson, S. and Holloway, J. and Pearce, R. and Dowling, Z. and Thomas, P. and others}, title = {{A randomized controlled trial of the effects of multi-sensory stimulation (MSS) for people with dementia}}, journal = {The British journal of clinical psychology}, year = {2001}, doi = {10.1348/014466501163508}, pmid = {11317951}, url = {https://doi.org/10.1348/014466501163508} } @article{gentry2026-42421660, author = {Gentry, Amanda and Sereika, Susan M. and Erickson, Kirk I. and McCall, Maura K. and Belcher, Sarah M. and Cummings, Meredith and Cho, Myeong-Ga and Brufsky, Eliza and others}, title = {{The relationship of neighborhood socioeconomic disadvantage and pretreatment cancer‐related cognitive impairment in women with breast cancer: A post hoc analysis of a randomized controlled trial}}, journal = {Cancer}, year = {2026}, doi = {10.1002/cncr.70506}, pmid = {42421660}, url = {https://doi.org/10.1002/cncr.70506} } @article{abdelhalim2025-40095192, author = {Abdelhalim, D. and Ahmed, Marwa and Hussein, Hoda Abdou and Sarhan, Mai Diaa and Khalaf, Ola Osama}, title = {{A Skill-Based multimodal intervention for dementia caregivers: impact on burden and anxiety}}, journal = {Aging Clinical and Experimental Research}, year = {2025}, doi = {10.1007/s40520-025-02985-x}, pmid = {40095192}, url = {https://doi.org/10.1007/s40520-025-02985-x} } @article{kang2025-40894462, author = {Kang, Hyun and Ihara, Emily S. and Tompkins, Catherine J. and Lauber, Mckenzie}, title = {{Boosting Cognitive Training through Social Engagement: Impacts on Older Adults With Subjective Cognitive Decline}}, journal = {Sage Open Aging}, year = {2025}, doi = {10.1177/30495334251366575}, pmid = {40894462}, url = {https://doi.org/10.1177/30495334251366575} } @article{ploeg2018-31518230, author = {Ploeg, J. and McAiney, C. and Duggleby, W. and Chambers, T. and Lam, A. and Peacock, S. and Fisher, K. and Forbes, D. A. and others}, title = {{A Web-Based Intervention to Help Caregivers of Older Adults With Dementia and Multiple Chronic Conditions: Qualitative Study}}, journal = {JMIR aging}, year = {2018}, doi = {10.2196/aging.8475}, pmid = {31518230}, url = {https://doi.org/10.2196/aging.8475} } @article{scott2001-11687043, author = {Scott, H. D. and Laake, K.}, title = {{Statins for the reduction of risk of Alzheimer's disease}}, journal = {The Cochrane database of systematic reviews}, year = {2001}, doi = {10.1002/14651858.cd003160}, pmid = {11687043}, url = {https://doi.org/10.1002/14651858.cd003160} } @article{chhetri2018-29405230, author = {Chhetri, J. K. and de Souto Barreto, P. and Cantet, C. and Cesari, M. and Coley, N. and Andrieu, S. and Vellas, B.}, title = {{Trajectory of the MAPT-PACC-Preclinical Alzheimer Cognitive Composite in the Placebo Group of a Randomized Control Trial: Results from the MAPT Study: Lessons for Further Trials}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2018}, doi = {10.14283/jpad.2017.21}, pmid = {29405230}, url = {https://doi.org/10.14283/jpad.2017.21} } @article{yang2022-33988909, author = {Yang, L. and Xuan, C. and Yu, C. and Jin, X. and Zheng, P. and Yan, J.}, title = {{Effects of comprehensive intervention on life quality among the elderly with Alzheimer Disease and their caregivers based on mixed models}}, journal = {Nursing open}, year = {2022}, doi = {10.1002/nop2.917}, pmid = {33988909}, url = {https://doi.org/10.1002/nop2.917} } @article{nourhashemi2008-18373036, author = {Nourhashemi, F. and Gillette-Guyonnet, S. and Andrieu, S. and Rolland, Y. and Ousset, P. J. and Vellas, B. and {PLASA group}}, title = {{A randomized trial of the impact of a specific care plan in 1120 Alzheimer's patients (PLASA Study) over a two-year period: design and baseline data}}, journal = {The journal of nutrition, health \& aging}, year = {2008}, doi = {10.1007/bf02982632}, pmid = {18373036}, url = {https://doi.org/10.1007/bf02982632} } @article{mcmanus2022-35220356, author = {McManus, K. R. and Lapid, M. I. and Forester, B. P. and Mueller, M. and Hermida, A. P. and Nykamp, L. and Harper, D. G. and Seiner, S. J. and others}, title = {{Simulated Electroconvulsive Therapy: A Novel Approach to a Control Group in Clinical Trials}}, journal = {The journal of ECT}, year = {2022}, doi = {10.1097/yct.0000000000000832}, pmid = {35220356}, url = {https://doi.org/10.1097/yct.0000000000000832} } @article{korthauer2024-39412840, author = {Korthauer, L. E. and Rosen, R. K. and Tremont, G. and Davis, J. D.}, title = {{Intervention Development for Tailored Education for Aging and Cognitive Health (TEACH) for Dementia Prevention in Midlife Adults: Protocol for a Randomized Controlled Trial}}, journal = {JMIR research protocols}, year = {2024}, doi = {10.2196/60395}, pmid = {39412840}, url = {https://doi.org/10.2196/60395} } @article{christakou2024-39766459, author = {Christakou, A. and Bouzineki, C. and Pavlou, M. and Stranjalis, G. and Sakellari, V.}, title = {{Effects of Mental Imagery on Quality of Life, Cognitive, and Emotional Status in Older Adults with Early-Stage Alzheimer's Disease Dementia: A Randomized Controlled Trial}}, journal = {Brain sciences}, year = {2024}, doi = {10.3390/brainsci14121260}, pmid = {39766459}, url = {https://doi.org/10.3390/brainsci14121260} } @article{davis2019-31002403, author = {Davis, M. L. and Hendrickson, J. and Wilson, N. and Shrestha, S. and Amspoker, A. B. and Kunik, M.}, title = {{Taking Care of the Dyad: Frequency of Caregiver Assessment Among Veterans with Dementia}}, journal = {Journal of the American Geriatrics Society}, year = {2019}, doi = {10.1111/jgs.15882}, pmid = {31002403}, url = {https://doi.org/10.1111/jgs.15882} } @article{mamo2018-30304320, author = {Mamo, S. K. and Reed, N. S. and Price, C. and Occhipinti, D. and Pletnikova, A. and Lin, F. R. and Oh, E. S.}, title = {{Hearing Loss Treatment in Older Adults With Cognitive Impairment: A Systematic Review}}, journal = {Journal of speech, language, and hearing research : JSLHR}, year = {2018}, doi = {10.1044/2018_jslhr-h-18-0077}, pmid = {30304320}, url = {https://doi.org/10.1044/2018_jslhr-h-18-0077} } @article{langford2015-26491262, author = {Langford, Dolores and Ashe, Maureen C. and Fleig, Lena and Panagiotopoulos, Kostas and Cho, Nancy and Ledoyen, Monique and Frost, Maeve and Sharpe, Nina and others}, title = {{Back to the future – feasibility of recruitment and retention to patient education and telephone follow-up after hip fracture: a pilot randomized controlled trial}}, journal = {Patient Preference and Adherence}, year = {2015}, doi = {10.2147/ppa.s86922}, pmid = {26491262}, url = {https://doi.org/10.2147/ppa.s86922} } @article{fredriksengoldsen2025-40253707, author = {Fredriksen‐Goldsen, Karen I. and Kim, Hyun‐Jun and Teri, Linda and Jones‐Cobb, Brittany and La Fazia, David and Petros, Ryan and Berridge, Clara W. and Prasad, Anyah and others}, title = {{Older adults living with Alzheimer’s Disease, dementia or mild cognitive impairment with no informal caregiver or care partner: IDEA Café, the first pilot randomized trial intervention for this underserved populations}}, journal = {Aging \& Mental Health}, year = {2025}, doi = {10.1080/13607863.2025.2468893}, pmid = {40253707}, url = {https://doi.org/10.1080/13607863.2025.2468893} } @article{silva2025-40640060, author = {Silva, Ana Filipa and de Assis, Gilmara Gomes and Silva, Rui and Murawska‐Ciałowicz, Eugenia and Żurek, Grzegorz and Carvalho, José and Roriz, Mafalda Sofia and Azevedo, José and others}, title = {{The differential effect of strength, cognitive and aerobic training combinations on cognitive performance and functional abilities in elderly with cognitive decline: The Fit4Alz project}}, journal = {The Journal of Prevention of Alzheimer s Disease}, year = {2025}, doi = {10.1016/j.tjpad.2025.100267}, pmid = {40640060}, url = {https://doi.org/10.1016/j.tjpad.2025.100267} } @article{khan2026-41918619, author = {Khan, Abdur Raheem and Aafreen, Aafreen and Khan, Ashfaque and Ganesh, G. Shankar and Aldhahi, Monira Ibrahim and Alshehri, Mohammed M. and Shaphe, Mohammad Abu}, title = {{Effects of aerobic exercise and computer-based cognitive training on cognition, functional independence, quality of life, and salivary cortisol levels in older adults with mild cognitive impairment: a randomized trial}}, journal = {Frontiers in Aging Neuroscience}, year = {2026}, doi = {10.3389/fnagi.2026.1776069}, pmid = {41918619}, url = {https://doi.org/10.3389/fnagi.2026.1776069} } @article{jung2026-41938858, author = {Jung, Jae Youn and Hong, Chang Hyung and Park, Yoo Kyoung and Moon, So Young and Jeong, Jee Hyang and Park, Hee Kyung and Choi, Seong Hye and Back, Joung Hwan and others}, title = {{Association of the Big Five personality traits with cognitive decline: a 24-week multidomain intervention study}}, journal = {Frontiers in Psychiatry}, year = {2026}, doi = {10.3389/fpsyt.2026.1797887}, pmid = {41938858}, url = {https://doi.org/10.3389/fpsyt.2026.1797887} } @article{yeon2025-40696527, author = {Yeon, Jeon So and Sheng-Min, Wang and Woong, Roh Hyun and You, Kim Keun and Young, Chang Yoon and Eosu, Kim and Jae-Nam, Bae and Seung-Ho, Ryu}, title = {{Practical Guide of the Korean Association for Geriatric Psychiatry to Anti-Amyloid Monoclonal Antibody Therapy for Alzheimer's Disease: Focused on Lecanemab}}, journal = {Journal of Korean medical science}, year = {2025}, doi = {10.3346/jkms.2025.40.e215}, pmid = {40696527}, url = {https://doi.org/10.3346/jkms.2025.40.e215} } @article{baker2003-12611754, author = {Baker, L. D. and Sambamurti, K. and Craft, S. and Cherrier, M. and Raskind, M. A. and Stanczyk, F. Z. and Plymate, SR. and Asthana, S.}, title = {{17beta-estradiol reduces plasma Abeta40 for HRT-naïve postmenopausal women with Alzheimer disease: a preliminary study}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2003}, doi = {10.1097/00019442-200303000-00015}, pmid = {12611754}, url = {https://doi.org/10.1097/00019442-200303000-00015} } @article{pfaff2025-39922302, author = {Pfaff, M. and Hoffmann, W. and Boekholt, M. and Biernetzky, O. and Blotenberg, I. and Afrin, D. and Platen, M. and Teipel, S. and Thyrian, JR. and Kilimann, I. and Michalowsky, B.}, title = {{Cost-Effectiveness of a Digitally Supported Care Management Program for Caregivers of People With Dementia}}, journal = {Value in Health}, year = {2025}, doi = {10.1016/j.jval.2025.01.011}, pmid = {39922302}, url = {https://doi.org/10.1016/j.jval.2025.01.011} } @article{tawfik2021-33971764, author = {Tawfik, N. M. and Sabry, N. A. and Darwish, H. and Mowafy, M. and Soliman, S. S. A.}, title = {{Psychoeducational Program for the Family Member Caregivers of People with Dementia to Reduce Perceived Burden and Increase Patient's Quality of Life: A Randomized Controlled Trial}}, journal = {Journal of primary care \& community health}, year = {2021}, doi = {10.1177/21501327211014088}, pmid = {33971764}, url = {https://doi.org/10.1177/21501327211014088} } @article{kawashima2013-23412645, author = {Kawashima, R.}, title = {{Mental exercises for cognitive function: clinical evidence}}, journal = {Journal of preventive medicine and public health = Yebang Uihakhoe chi}, year = {2013}, doi = {10.3961/jpmph.2013.46.s.s22}, pmid = {23412645}, url = {https://doi.org/10.3961/jpmph.2013.46.s.s22} } @article{boutilier2022-35925654, author = {Boutilier, J. J. and Loganathar, P. and Linden, A. and Scheer, E. and Noejovich, S. and Elliott, C. and Zuraw, M. and Werner, N. E.}, title = {{A Web-Based Platform (CareVirtue) to Support Caregivers of People Living With Alzheimer Disease and Related Dementias: Mixed Methods Feasibility Study}}, journal = {JMIR aging}, year = {2022}, doi = {10.2196/36975}, pmid = {35925654}, url = {https://doi.org/10.2196/36975} } @article{bourgeois2016-26728933, author = {Bourgeois, J. and Laye, M. and Lemaire, J. and Leone, E. and Deudon, A. and Darmon, N. and Giaume, C. and Lafont, V. and others}, title = {{Relearning of Activities of Daily Living: A Comparison of the Effectiveness of Three Learning Methods in Patients with Dementia of the Alzheimer Type}}, journal = {The journal of nutrition, health \& aging}, year = {2016}, doi = {10.1007/s12603-016-0675-4}, pmid = {26728933}, url = {https://doi.org/10.1007/s12603-016-0675-4} } @article{disalvo2018-30106321, author = {Disalvo, D. and Luckett, T. and Luscombe, G. and Bennett, A. and Davidson, P. and Chenoweth, L. and Mitchell, G. and Pond, D. and others}, title = {{Potentially Inappropriate Prescribing in Australian Nursing Home Residents with Advanced Dementia: A Substudy of the IDEAL Study}}, journal = {Journal of palliative medicine}, year = {2018}, doi = {10.1089/jpm.2018.0070}, pmid = {30106321}, url = {https://doi.org/10.1089/jpm.2018.0070} } @article{almaraz2009-19590387, author = {Almaraz, A. C. and Driver-Dunckley, E. D. and Woodruff, B. K. and Wellik, K. E. and Caselli, R. J. and Demaerschalk, B. M. and Adler, C. H. and Caviness, J. N. and others}, title = {{Efficacy of rivastigmine for cognitive symptoms in Parkinson disease with dementia}}, journal = {The neurologist}, year = {2009}, doi = {10.1097/nrl.0b013e3181a968df}, pmid = {19590387}, url = {https://doi.org/10.1097/nrl.0b013e3181a968df} } @article{scholz2018-30333067, author = {Scholz, R. and Lemcke, J. and Meier, U. and Stengel, D.}, title = {{Efficacy and safety of programmable compared with fixed anti-siphon devices for treating idiopathic normal-pressure hydrocephalus (iNPH) in adults - SYGRAVA: study protocol for a randomized trial}}, journal = {Trials}, year = {2018}, doi = {10.1186/s13063-018-2951-6}, pmid = {30333067}, url = {https://doi.org/10.1186/s13063-018-2951-6} } @article{wagner2004-15492346, author = {Wagner, Edward H.}, title = {{Deconstructing Heart Failure Disease Management}}, journal = {Annals of Internal Medicine}, year = {2004}, doi = {10.7326/0003-4819-141-8-200410190-00015}, pmid = {15492346}, url = {https://doi.org/10.7326/0003-4819-141-8-200410190-00015} } @article{reid2023-38094939, author = {Reid, M. Carrington and Pillemer, Karl Andrew}, title = {{Introduction to Special Issue: Translational Research on Pain and Pain Management in Later Life}}, journal = {Innovation in Aging}, year = {2023}, doi = {10.1093/geroni/igad119}, pmid = {38094939}, url = {https://doi.org/10.1093/geroni/igad119} } @article{mesquita2025-41305626, author = {Mesquita, Andreia and de Sousa, Daniela and Padrão, Patrícia and Costa, Ana Rute and Moreira, Pedro Augusto Maciel}, title = {{Challenging the Wine Component in Mediterranean Diet Scores: Cognitive Outcomes in Portuguese Adults at High Risk of Dementia}}, journal = {Nutrients}, year = {2025}, doi = {10.3390/nu17223576}, pmid = {41305626}, url = {https://doi.org/10.3390/nu17223576} } @article{lee2026-41561087, author = {Lee, Chun Kiat and Woodward, Michael and Hohenberg, Mark I. and Tang, Julian Wei-Tze}, title = {{Charting the research frontier for viral infections, immunomodulation, and dementia: a perspective on synaptic biomarkers as essential clinical trial endpoints}}, journal = {Frontiers in Cellular and Infection Microbiology}, year = {2026}, doi = {10.3389/fcimb.2025.1701760}, pmid = {41561087}, url = {https://doi.org/10.3389/fcimb.2025.1701760} } @article{choi2025-41266554, author = {Choi, Ha Yeong and Kim, Yeo Jin and Son, Dae‐Soon and Ahn, Moo Eob and Lee, Sang Gyu}, title = {{Effectiveness of a 52-week multidomain intervention to maintain cognitive function in patients with mild cognitive impairment: a randomized controlled trial}}, journal = {Scientific Reports}, year = {2025}, doi = {10.1038/s41598-025-24865-0}, pmid = {41266554}, url = {https://doi.org/10.1038/s41598-025-24865-0} } @article{sugimoto2025-40046640, author = {Sugimoto, Taiki and Uchida, Kazuaki and Yokoyama, Yoko and Onoyama, Ayaka and Fujita, Kosuke and Kuroda, Yujiro and Hinakura, Keigo and Ogawa, Susumu and others}, title = {{Adherence and aerobic exercise intensity in live online exercise sessions for older adults with mild cognitive impairment: Insights from the Japan-Multimodal Intervention Trial for the Prevention of Dementia}}, journal = {Journal of Aging Research and Lifestyle}, year = {2025}, doi = {10.1016/j.jarlif.2025.100003}, pmid = {40046640}, url = {https://doi.org/10.1016/j.jarlif.2025.100003} } @article{vangils2026-41508135, author = {van Gils, Veerle and Waterink, Lisa and Wimmers, S. C. P. M. and Jelsma, J.G.M. and de Vugt, Marjolein Elizabeth and Handels, Ron L. H. and Sikkes, Sietske A.M. and van der Flier, Wiesje M. and others}, title = {{The Lifestyle Intervention in memory clinics of General and academic Hospitals Trial (LIGHT): Rationale and study design of a randomized controlled trial to reduce modifiable dementia risk}}, journal = {Alzheimer s Research \& Therapy}, year = {2026}, doi = {10.1186/s13195-025-01947-9}, pmid = {41508135}, url = {https://doi.org/10.1186/s13195-025-01947-9} } @article{scheuermann2025-40306986, author = {Scheuermann, Julia-Sophia and Scheerbaum, Petra and Liu, Yu and Ding, Yaping and Lu, Jianwen and Zhong, Ming and Su, Jian and Gefeller, Olaf and others}, title = {{SinoMAKS—protocol of a randomised controlled trial to evaluate the Chinese version of the non-pharmacological, multimodal MAKS intervention for people with mild to moderate dementia in Chinese nursing homes}}, journal = {BMJ Open}, year = {2025}, doi = {10.1136/bmjopen-2024-093618}, pmid = {40306986}, url = {https://doi.org/10.1136/bmjopen-2024-093618} } @article{chow2007-19300592, author = {Chow, T. W. and Pollock, B. G. and Milgram, N. W.}, title = {{Potential cognitive enhancing and disease modification effects of SSRIs for Alzheimer's disease}}, journal = {Neuropsychiatric disease and treatment}, year = {2007}, pmid = {19300592} } @article{chhugani2018-31370033, author = {Chhugani, K. J. and Metri, K. and Babu, N. and Nagendra, H. R.}, title = {{Effects of Integrated Yoga Intervention on Psychopathologies and Sleep Quality Among Professional Caregivers of Older Adults With Alzheimer's Disease: A Controlled Pilot Study}}, journal = {Advances in mind-body medicine}, year = {2018}, pmid = {31370033} } @article{nielsen2016-27094158, author = {Nielsen, A. B. and Siersma, V. and Waldemar, G. and Waldorff, F. B.}, title = {{Poor self-rated health did not increase risk of permanent nursing placement or mortality in people with mild Alzheimer's disease}}, journal = {BMC geriatrics}, year = {2016}, doi = {10.1186/s12877-016-0262-x}, pmid = {27094158}, url = {https://doi.org/10.1186/s12877-016-0262-x} } @article{koepsell2007-17984455, author = {Koepsell, T. D. and Chi, Y. Y. and Zhou, X. H. and Lee, W. W. and Ramos, E. M. and Kukull, W. A.}, title = {{An alternative method for estimating efficacy of the AN1792 vaccine for Alzheimer disease}}, journal = {Neurology}, year = {2007}, doi = {10.1212/01.wnl.0000278226.96003.f8}, pmid = {17984455}, url = {https://doi.org/10.1212/01.wnl.0000278226.96003.f8} } @article{matsumoto2022-35112011, author = {Matsumoto, Hiroshige and Igarashi, Ayumi and Hagiwara, Yasuhiro and Yamamoto‐Mitani, Noriko}, title = {{Relational Design for Dementia and Job Significance (ReDeSign): Study protocol for a randomized controlled trial of an online dementia training for retail workers}}, journal = {Contemporary Clinical Trials Communications}, year = {2022}, doi = {10.1016/j.conctc.2022.100896}, pmid = {35112011}, url = {https://doi.org/10.1016/j.conctc.2022.100896} } @article{huang2025-41433843, author = {Huang, Pei and Gao, Chao and Tan, Yuyan and Chen, Shengdi and Ling, Yun and Chen, Zhonglue and Zhou, Zhixing and Xia, Huanhuan}, title = {{A Four‐Arm Randomized Controlled Trial on the Effects of Multi‐Dimensional Cognitive Intervention in Parkinson's Disease Patients with Mild Cognitive Impairment and Subjective Cognitive Decline (REMIND)}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz70860_098518}, pmid = {41433843}, url = {https://doi.org/10.1002/alz70860_098518} } @article{voigt2026-41958469, author = {Voigt, Robin M. and Chaudhary, Adit and Naqib, Ankur D and Engen, Phillip A. and Adnan, Darbaz and Dhana, Klodian and Green, Stefan J. and Villanueva, Michelle and others}, title = {{Weight loss and metabolic improvements dominate the microbiome response in the MIND diet intervention: a randomized controlled trial}}, journal = {Alzheimer s \& Dementia Translational Research \& Clinical Interventions}, year = {2026}, doi = {10.1002/trc2.70239}, pmid = {41958469}, url = {https://doi.org/10.1002/trc2.70239} } @article{attarha2025-41084791, author = {Attarha, Mouna and Pelegrino, Ana de Figueiredo and Ouellet, Lydia and Toussaint, Paule‐Joanne and Grant, Sarah-Jane and Van Vleet, Thomas and de Villers‐Sidani, Etienne}, title = {{Effects of Computerized Cognitive Training on Vesicular Acetylcholine Transporter Levels using [18F]Fluoroethoxybenzovesamicol Positron Emission Tomography in Healthy Older Adults: Results from the Improving Neurological Health in Aging via Neuroplasticity-based Computerized Exercise (INHANCE) Randomized Clinical Trial}}, journal = {JMIR Serious Games}, year = {2025}, doi = {10.2196/75161}, pmid = {41084791}, url = {https://doi.org/10.2196/75161} } @article{greene2025-40928757, author = {Greene, Leanne and Allan, Louise M. and Bingham, Alison and Sharma, Ashima K. and Whale, Bethany and Barber, Robert and Fox, Christopher and Goodwin, Victoria A and others}, title = {{Maintaining independence at home after a fall: a process evaluation of the MAINTAIN multicomponent intervention for people living with dementia}}, journal = {Age and Ageing}, year = {2025}, doi = {10.1093/ageing/afaf245}, pmid = {40928757}, url = {https://doi.org/10.1093/ageing/afaf245} } @article{torke2025-40413042, author = {Torke, Alexia M. and Hickman, Susan E. and Wocial, Lucia D. and Monahan, Patrick O. and Burke, Emily S. and Slaven, James E. and Ziemba, Kathleen and Montgomery, Carole and others}, title = {{Planning Ahead: protocol for a randomised trial of advance care planning for community dwelling older adults at increased mortality risk}}, journal = {BMJ Open}, year = {2025}, doi = {10.1136/bmjopen-2025-102186}, pmid = {40413042}, url = {https://doi.org/10.1136/bmjopen-2025-102186} } @article{kazuhiro2019-30878823, author = {Kazuhiro, Harada and Sangyoon, Lee and Sungchul, Lee and Seongryu, Bae and Kenji, Harada and Hiroyuki, Shimada}, title = {{Environmental predictors of objectively measured out-of-home time among older adults with cognitive decline}}, journal = {Archives of gerontology and geriatrics}, year = {2019}, doi = {10.1016/j.archger.2019.01.021}, pmid = {30878823}, url = {https://doi.org/10.1016/j.archger.2019.01.021} } @article{ruthirakuhan2026-42178577, author = {Ruthirakuhan, M. and Mills, M. and Rosenberg, P. and Haughey, N. and Mintzer, J. and Brawman-Mintzer, O. and Craft, S. and Herrmann, N. and others}, title = {{Uncovering lipid biomarkers linked to methylphenidate efficacy in treating apathy in Alzheimer's disease: insights from the ADMET 2 trial}}, journal = {Alzheimer's research \& therapy}, year = {2026}, doi = {10.1186/s13195-026-02055-y}, pmid = {42178577}, url = {https://doi.org/10.1186/s13195-026-02055-y} } @article{scott2001-11687176, author = {Scott, H. D. and Laake, K.}, title = {{Statins for the prevention of Alzheimer's disease}}, journal = {The Cochrane database of systematic reviews}, year = {2001}, doi = {10.1002/14651858.cd003160}, pmid = {11687176}, url = {https://doi.org/10.1002/14651858.cd003160} } @article{holden2018-30246863, author = {Holden, T. R. and Keller, S. and Kim, A. and Gehring, M. and Schmitz, E. and Hermann, C. and Gilmore-Bykovskyi, A. and Kind, A. J. H.}, title = {{Procedural Framework to Facilitate Hospital-Based Informed Consent for Dementia Research}}, journal = {Journal of the American Geriatrics Society}, year = {2018}, doi = {10.1111/jgs.15525}, pmid = {30246863}, url = {https://doi.org/10.1111/jgs.15525} } @article{wang2018-29580264, author = {Wang, S. and Hammes, J. and Khan, S. and Gao, S. and Harrawood, A. and Martinez, S. and Moser, L. and Perkins, A. and others}, title = {{Improving Recovery and Outcomes Every Day after the ICU (IMPROVE): study protocol for a randomized controlled trial}}, journal = {Trials}, year = {2018}, doi = {10.1186/s13063-018-2569-8}, pmid = {29580264}, url = {https://doi.org/10.1186/s13063-018-2569-8} } @article{li2024-38430153, author = {Li, Fei and Hu, Fengxia and Liang, Yi and Liang, Fen and Tan, Huiqun and Xing, Sisi}, title = {{Post-discharge Follow-up of Standardized Management for Patients with Post-stroke Cognitive Impairment}}, journal = {Alternative therapies in health and medicine}, year = {2024}, pmid = {38430153} } @article{fredriksengoldsen2025-41387197, author = {Fredriksen‐Goldsen, Karen I. and Teri, Linda L and Kim, Hyun‐Jun and Jones‐Cobb, Brittany and LaFazia, David M. and McKenzie, Glenise L. and Petros, Ryan and Jung, Hailey H. and others}, title = {{Innovations in Dementia Empowerment and Action: RCT for Underserved Communities}}, journal = {Journal of the American Geriatrics Society}, year = {2025}, doi = {10.1111/jgs.70189}, pmid = {41387197}, url = {https://doi.org/10.1111/jgs.70189} } @article{ide2025-40397393, author = {Ide, Keiko and Mizushima, Shunsaku and Saito, Kyoko and Suzuki, Hiroko and Chiba, Yuhei and Abe, Kie and Yoshimi, Asuka and Hishimoto, Akitoyo and others}, title = {{Japan-multimodal intervention trial for the prevention of dementia in older people with lifestyle-related diseases: A community-based, 18-month, randomized controlled trial}}, journal = {Journal of Alzheimer s Disease}, year = {2025}, doi = {10.1177/13872877251344222}, pmid = {40397393}, url = {https://doi.org/10.1177/13872877251344222} } @article{chiu2026-41781884, author = {Chiu, Hsien-Chun and Hsieh, Yu-Wei and Cheng, Chia‐Hsiung}, title = {{Baseline predictors of neurophysiological response to combined physical and cognitive training in older adults with subjective cognitive decline}}, journal = {BMC Geriatrics}, year = {2026}, doi = {10.1186/s12877-026-07270-8}, pmid = {41781884}, url = {https://doi.org/10.1186/s12877-026-07270-8} } @article{moin2025-40331620, author = {Moin, Emily E. and Bayes, Brian A. and Madden, Vanessa L. and Halpern, Scott D. and Courtright, Katherine R.}, title = {{Disease and Race‐Based Differences in Inpatient Palliative Care Consultation in Cancer and Noncancer Serious Illnesses}}, journal = {Journal of the American Geriatrics Society}, year = {2025}, doi = {10.1111/jgs.19509}, pmid = {40331620}, url = {https://doi.org/10.1111/jgs.19509} } @article{uchiyamatanaka2024-38999825, author = {Uchiyama-Tanaka, Y. and Yamakage, H. and Inui, T.}, title = {{The Effects of Dietary Intervention and Macrophage-Activating Factor Supplementation on Cognitive Function in Elderly Users of Outpatient Rehabilitation}}, journal = {Nutrients}, year = {2024}, doi = {10.3390/nu16132078}, pmid = {38999825}, url = {https://doi.org/10.3390/nu16132078} } @article{ross2013-23968157, author = {Ross, J. and Sharma, S. and Winston, J. and Nunez, M. and Bottini, G. and Franceschi, M. and Scarpini, E. and Frigerio, E. and others}, title = {{CHF5074 reduces biomarkers of neuroinflammation in patients with mild cognitive impairment: a 12-week, double-blind, placebo-controlled study}}, journal = {Current Alzheimer research}, year = {2013}, doi = {10.2174/13892037113149990144}, pmid = {23968157}, url = {https://doi.org/10.2174/13892037113149990144} } @article{paunescu2020-32118591, author = {Paunescu, H. and Dima, L. and Ghita, I. and Coman, L. and Ifteni, P. I. and Fulga, I. and Coman, O. A.}, title = {{A Systematic Review of Clinical Studies on the Effect of Psychoactive Cannabinoids in Psychiatric Conditions in Alzheimer Dementia}}, journal = {American journal of therapeutics}, year = {2020}, doi = {10.1097/mjt.0000000000001120}, pmid = {32118591}, url = {https://doi.org/10.1097/mjt.0000000000001120} } @article{duggleby2020-32778059, author = {Duggleby, W. and O'Rourke, H. and Swindle, J. and Peacock, S. and McAiney, C. and Baxter, P. and Thompson, G. and Dubé, V. and others}, title = {{Study protocol: pragmatic randomized control trial of my tools 4 care- in care (MT4C-in care) a web-based tool for family Carers of persons with dementia residing in long term care}}, journal = {BMC geriatrics}, year = {2020}, doi = {10.1186/s12877-020-01690-w}, pmid = {32778059}, url = {https://doi.org/10.1186/s12877-020-01690-w} } @article{wright2025-40146982, author = {Wright, K. D. and Richards Adams, I. K. and Helsabeck, N. P. and Rose, K. M. and Moss, K. O. and Nemati, D. and Palmer, N. and Kim, B. and others}, title = {{Stress and Hypertension Among African American Female Family Caregivers of Persons Living With Alzheimer Disease and Related Dementias: Protocol for a Pilot Internet-Based Randomized Controlled Trial}}, journal = {JMIR research protocols}, year = {2025}, doi = {10.2196/66975}, pmid = {40146982}, url = {https://doi.org/10.2196/66975} } @article{oloughlin2021-34328428, author = {O'Loughlin, P. and Pavithra, P. and Regan, J. and Bennett, M. and Knight, R. and Lenaert, B. and Marquez, M. and Taddeo, M. and others}, title = {{A Randomized Controlled Trial Investigating the Feasibility of a Low-Intensity Psychological Intervention for Fear of Memory Loss and Quality of Life in Older Adults: Protocol for the Reducing Fear and Avoidance of Memory Loss (REFRAME) Study}}, journal = {JMIR research protocols}, year = {2021}, doi = {10.2196/30514}, pmid = {34328428}, url = {https://doi.org/10.2196/30514} } @article{turner2013-23815530, author = {Turner, J. Rick}, title = {{Patient and Physician Adherence in Hypertension Management}}, journal = {Journal of Clinical Hypertension}, year = {2013}, doi = {10.1111/jch.12105}, pmid = {23815530}, url = {https://doi.org/10.1111/jch.12105} } @article{justohenriques2025-93926460, author = {Justo‐Henriques, Susana I. and da Silva, Rosa Carla Gomes and Pérez, Enrique and Carvalho, Janessa O.}, title = {{Cognitive and Psychosocial Effects of Individual Cognitive Stimulation in Dementia: A Randomized Controlled Trial}}, journal = {Journal of Psychosocial Rehabilitation and Mental Health}, year = {2025}, doi = {10.1007/s40737-025-00489-5}, url = {https://doi.org/10.1007/s40737-025-00489-5} } @article{chung2025-41220868, author = {Chung, S. S. and Kim, Bori R. and Moon, Sooin and Kim, Geon Ha}, title = {{Effects of a 12-Week Hybrid Analog–Digital Cognitive Training on Cognitively Unimpaired Older Adults: A Pilot Single-Blind Randomized Controlled Trial}}, journal = {Dementia and Neurocognitive Disorders}, year = {2025}, doi = {10.12779/dnd.2025.24.4.301}, pmid = {41220868}, url = {https://doi.org/10.12779/dnd.2025.24.4.301} } @article{luttenberger2010-20478097, author = {Luttenberger, K. and Graessel, E.}, title = {{Recording care time in nursing homes: development and validation of the "RUD-FOCA" (Resource Utilization in Dementia-Formal Care)}}, journal = {International psychogeriatrics}, year = {2010}, doi = {10.1017/s1041610210000487}, pmid = {20478097}, url = {https://doi.org/10.1017/s1041610210000487} } @article{heffner2025-40454426, author = {Heffner, Kathi L. and Crean, Hugh F. and Gallegos, Autumn M. and Quiñones-Cordero, Maria M and Weber, Miriam T. and Sörensen, Silvia and Lin, Rose Sin Yi and Podgorski, Carol Ann and others}, title = {{Speed of Processing Training for Stress Adaptation in Caregivers of a Family Member With Dementia: A Randomized Controlled Trial}}, journal = {Innovation in Aging}, year = {2025}, doi = {10.1093/geroni/igaf033}, pmid = {40454426}, url = {https://doi.org/10.1093/geroni/igaf033} } @article{rachael2025-42712339, author = {Rachael, Brooks and Hoevenaar-Blom Marieke, P. and Nicola, Coley and Moll van Charante Eric, P. and Linda, Barnes and Edo, Richard and Carol, Brayne}, title = {{Smartphone barrier: uncovering the digital divide in mHealth prevention among disadvantaged middle-aged and older-aged UK communities}}, journal = {BMJ digital health \& AI}, year = {2025}, doi = {10.1136/bmjdhai-2025-000069}, pmid = {42712339}, url = {https://doi.org/10.1136/bmjdhai-2025-000069} } @article{alves2013-23314062, author = {Alves, J. and Magalhães, R. and Thomas, R. E. and Gonçalves, O. F. and Petrosyan, A. and Sampaio, A.}, title = {{Is there evidence for cognitive intervention in Alzheimer disease? A systematic review of efficacy, feasibility, and cost-effectiveness}}, journal = {Alzheimer disease and associated disorders}, year = {2013}, doi = {10.1097/wad.0b013e31827bda55}, pmid = {23314062}, url = {https://doi.org/10.1097/wad.0b013e31827bda55} } @article{kim2023-37403351, author = {Kim, A. and Lee, J. and Moon, H. and Kim, C. and Yoo, M. Y. and Park, W. Y. and Kim, W. D. and Seo, Y. S.}, title = {{The effects of low-dose radiation therapy in patients with mild-to-moderate Alzheimer's dementia: an interim analysis of a pilot study}}, journal = {Radiation oncology journal}, year = {2023}, doi = {10.3857/roj.2023.00052}, pmid = {37403351}, url = {https://doi.org/10.3857/roj.2023.00052} } @article{xu2023-37676706, author = {Xu, L. and Fields, N. L. and Daniel, K. M. and Cipher, D. J. and Troutman, B. A.}, title = {{Reminiscence and Digital Storytelling to Improve the Social and Emotional Well-Being of Older Adults With Alzheimer's Disease and Related Dementias: Protocol for a Mixed Methods Study Design and a Randomized Controlled Trial}}, journal = {JMIR research protocols}, year = {2023}, doi = {10.2196/49752}, pmid = {37676706}, url = {https://doi.org/10.2196/49752} } @article{griffiths2006-16865841, author = {Griffiths, Peter}, title = {{Moving elderly inpatients to a transitional care facility reduced hospital stay but increased time to transfer to long term care}}, journal = {Evidence-Based Nursing}, year = {2006}, doi = {10.1136/ebn.9.3.90}, pmid = {16865841}, url = {https://doi.org/10.1136/ebn.9.3.90} } @article{vox2013-24160301, author = {Vox, Ford and Capron, Alexander Morgan and Kraus, Marilyn F. and Alexander, G. Caleb and Kirschner, Kristi L.}, title = {{Balancing Burdens and Benefits: Ethical Issues of Off‐Label Prescription Pharmaceutical Use}}, journal = {PM\&R}, year = {2013}, doi = {10.1016/j.pmrj.2013.08.601}, pmid = {24160301}, url = {https://doi.org/10.1016/j.pmrj.2013.08.601} } @article{marron2018-30185210, author = {Marron, E. M. and Viejo-Sobera, R. and Quintana, M. and Redolar-Ripoll, D. and Rodríguez, D. and Garolera, M.}, title = {{Transcranial magnetic stimulation intervention in Alzheimer's disease: a research proposal for a randomized controlled trial}}, journal = {BMC research notes}, year = {2018}, doi = {10.1186/s13104-018-3757-z}, pmid = {30185210}, url = {https://doi.org/10.1186/s13104-018-3757-z} } @article{potyk2005-16004170, author = {Potyk, D.}, title = {{Treatments for Alzheimer disease}}, journal = {Southern medical journal}, year = {2005}, doi = {10.1097/01.smj.0000166671.86815.c1}, pmid = {16004170}, url = {https://doi.org/10.1097/01.smj.0000166671.86815.c1} } @article{fedele1993-7716695, author = {Fedele, D. J. and Jones, J. A. and Volicer, L. and Herz, L. R. and Oppenheim, F. G.}, title = {{Effects of medication on parotid salivary flow rates in an individual with dementia of the Alzheimer type}}, journal = {Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry}, year = {1993}, doi = {10.1111/j.1754-4505.1993.tb01499.x}, pmid = {7716695}, url = {https://doi.org/10.1111/j.1754-4505.1993.tb01499.x} } @article{pasquini2022-36367770, author = {Pasquini, S. and Margaritini, A. and Gambella, E. and Di Rosa, M. and Maranesi, E. and Bevilacqua, R. and Civerchia, P. and Pelliccioni, G.}, title = {{A Psychosocial Intervention for Supporting Informal Caregivers of Older People With Alzheimer Disease: Protocol for the InnFamiglia Randomized Controlled Trial}}, journal = {JMIR research protocols}, year = {2022}, doi = {10.2196/37496}, pmid = {36367770}, url = {https://doi.org/10.2196/37496} } @article{ye2025-39985041, author = {Ye, Yi and Chen, Qing and Li, Ruixuan and Wang, Xiaoyi and Sun, Yueling and Li, Fangjiang and Liu, Xiaoping and Wang, Le and others}, title = {{The efficacy of computerized cognitive training in patients with coronary heart disease and cognitive impairment, no dementia: study protocol for a randomized controlled trial}}, journal = {Trials}, year = {2025}, doi = {10.1186/s13063-025-08745-6}, pmid = {39985041}, url = {https://doi.org/10.1186/s13063-025-08745-6} } @article{bouchelit2026-371ff4d0, author = {Bouchelit, Mohammed El Amin}, title = {{Stress-Specific Mitochondrial Reserve as a Candidate Modifier of Lipid-Driven Synaptic Failure in Alzheimer Disease}}, journal = {Zenodo (CERN European Organization for Nuclear Research)}, year = {2026}, doi = {10.5281/zenodo.21854145}, url = {https://doi.org/10.5281/zenodo.21854145} } @article{stott2018-310f7413, author = {Stott, David J}, title = {{Editor’s view}}, journal = {Age and Ageing}, year = {2018}, doi = {10.1093/ageing/afy187}, url = {https://doi.org/10.1093/ageing/afy187} } @article{vandersteen2025-644d01cf, author = {van der Steen, Jenny Theodora and Xu, Jingyuan and Tros, Willemijn and Blom, Jeanet W.}, title = {{Contrasting Approaches in Advance Care Planning in Dementia as Perceived by General Practitioners}}, journal = {Innovation in Aging}, year = {2025}, doi = {10.1093/geroni/igaf122.2219}, url = {https://doi.org/10.1093/geroni/igaf122.2219} } @article{nunomura2013-24291874, author = {Nunomura, A.}, title = {{[Oxidative stress hypothesis for Alzheimer's disease and its potential therapeutic implications]}}, journal = {Rinsho shinkeigaku = Clinical neurology}, year = {2013}, doi = {10.5692/clinicalneurol.53.1043}, pmid = {24291874}, url = {https://doi.org/10.5692/clinicalneurol.53.1043} } @article{study2023-955fa2a8, title = {{Interim Phase 1 multiple ascending dose results for remternetug (LY3372993) in Alzheimer's disease}}, journal = {Presented at AD/PD 2023 Conference (Gothenburg, Sweden); covered by ALZFORUM and NeurologyLive}, year = {2023} } @article{tzimas2026-4c0acdbc, author = {Tzimas, G. and Vanghelof, J. C. and Mohammed, A. and Raicu, D. S. and Du, L. and Ernst, M. E. and Warner, E. T. and Chan and others}, title = {{Aspirin and healthy longevity within racial and ethnic minoritized older adults in the United States}}, journal = {medRxiv (preprint)}, year = {2026}, doi = {10.64898/2026.08.24.26361036}, url = {https://doi.org/10.64898/2026.08.24.26361036} } @article{rafieirezvani2026-50b7bf22, author = {Rafiei Rezvani, F. and Azimi, D. and Nekouei, A. H. and Kim, H. and Sauer, C. C. and Wharton, W. and Qiu, D. and Goldstein and others}, title = {{Feasibility, Safety, and Preliminary Efficacy of Partnered Rhythmic Rehabilitation in Prodromal Alzheimer's Disease: A 12-Month Pilot Randomized Controlled Trial}}, journal = {medRxiv (preprint)}, year = {2026}, doi = {10.64898/2026.09.11.26362767}, url = {https://doi.org/10.64898/2026.09.11.26362767} } @article{froggatt2020-31971506, author = {Froggatt, K. and Best, A. and Bunn, F. and Burnside, G. and Coast, J. and Dunleavy, L. and Goodman, C. and Hardwick, B. and others}, title = {{A group intervention to improve quality of life for people with advanced dementia living in care homes: the Namaste feasibility cluster RCT}}, journal = {Health technology assessment (Winchester, England)}, year = {2020}, doi = {10.3310/hta24060}, pmid = {31971506}, url = {https://doi.org/10.3310/hta24060} } @article{gangannagaripalli2026-ef8883b6, author = {Gangannagaripalli, J. and Ahmed, S. and Parchment, A. and Shi, C. and Dlima, S. and Christie, R. and Todd, C. and Vardy, E. and others}, title = {{A digital programme to prevent falls and improve wellbeing in people living with dementia in the community: Quantitative results from the KOKU-LITE feasibility study}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.10.27.26366422}, url = {https://doi.org/10.64898/2026.10.27.26366422} } @article{boekholt2026-dc67c10d, author = {Boekholt, M. and Biernetzky, O. and Thyrian, JR. and Blotenberg, I. and Teipel, S. and Michalowsky, B. and Afrin, D. and Kilimann, I. and others}, title = {{Efficacy of care management in reducing needs of caregivers of people with dementia}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10521194/v1}, url = {https://doi.org/10.21203/rs.3.rs-10521194/v1} } @article{yildiz2026-01133a22, author = {Yildiz, M. and Winstead, V. and Jacob, A. and Nemariam, A. and Paul, N. and Pickering, C.}, title = {{The Effect of Noncontingent Monetary Incentives in Recruitment Letters on Research Enrollment of Alzheimer’s Disease and Related Dementia Caregiving Dyads: A Study Within a Trial (SWAT) Randomized Controlled Trial}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10818940/v1}, url = {https://doi.org/10.21203/rs.3.rs-10818940/v1} } @article{afifi2026-fb5f31f1, author = {Afifi, T. and Collins, N. and Rand, K. and Stamps, J. and Naffziger, E. and Truscelli, N. and Harris, P. and Neumann, T. and others}, title = {{The effects of virtual reality and video conferencing on personal and relational well-being among older adults with cognitive impairments and their adult children: The Thrive randomized controlled trial}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10584186/v1}, url = {https://doi.org/10.21203/rs.3.rs-10584186/v1} } @article{lau2026-f3bd773c, author = {Lau, Y. and Phannarus, H. and Cooper, C. and Walker, Z. and Demnitz-King, H. and Marchant, N. L.}, title = {{Differential association of step count with depressive and anxiety symptoms in older adults at risk of dementia}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.07.12.26357854}, url = {https://doi.org/10.64898/2026.07.12.26357854} } @article{sanchezmartinez2026-525e1fdd, author = {Sanchez-Martinez, J. and Solis-Urra, P. and Toval, A. and Coca-Pulido, A. and Rodríguez Palacios, M. T. and Sánchez-Aranda, L. and Bakker, E. A. and Martín-Fuentes, I. and others}, title = {{Effects of high-intensity interval training with or without resistance training on Alzheimer’s disease brain signatures in individuals with coronary artery disease: the Heart-Brain randomized controlled trial}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.07.02.26357035}, url = {https://doi.org/10.64898/2026.07.02.26357035} } @article{matev2025-d7d29632, author = {Matev, V. and Rothenberg, M. and Donath, J. and Cukaci, C. and Klöbl, M. and Al Barede, K. and Stöhrmann, P. and Dörl, G. and others}, title = {{The effects of vortioxetine versus placebo on cognitive functioning in mild cognitive impairment: a placebo-controlled, randomized, double-blind study}}, journal = {medRxiv}, year = {2025}, doi = {10.64898/2025.12.10.25341977}, url = {https://doi.org/10.64898/2025.12.10.25341977} } @article{xu2026-e75ce35c, author = {Xu, Y. and Pruzin, J. J. and Greene, T. and Williamson, J. and Reboussin, D. M. and Pajewski, N. M. and Klein, M. and Yau, W. and others}, title = {{Effect of Intensive vs Standard Blood Pressure Control According to APOE ε4 Genotype: A Secondary Analysis of SPRINT}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.07.02.26357167}, url = {https://doi.org/10.64898/2026.07.02.26357167} } @article{banerjee2013-23438937, author = {Banerjee, Sube and Hellier, Jennifer M. and Romeo, Renée and Dewey, Michael E. and Knapp, Martin Richard John and Ballard, Clive G. and Baldwin, R and Bentham, Peter and others}, title = {{Study of the use of antidepressants for depression in dementia: the HTA-SADD trial – a multicentre, randomised, double-blind, placebo-controlled trial of the clinical effectiveness and cost-effectiveness of sertraline and mirtazapine}}, journal = {Health Technology Assessment}, year = {2013}, doi = {10.3310/hta17070}, pmid = {23438937}, url = {https://doi.org/10.3310/hta17070} } @article{woods2012-23211271, author = {Woods, Bob T. and Bruce, E. and Edwards, RT and Elvish, Ruth and Hoare, Zoë and Hounsome, Barry and Keady, John David and Moniz-Cook, Esme D. and others}, title = {{REMCARE: reminiscence groups for people with dementia and their family caregivers – effectiveness and cost-effectiveness pragmatic multicentre randomised trial}}, journal = {Health Technology Assessment}, year = {2012}, doi = {10.3310/hta16480}, pmid = {23211271}, url = {https://doi.org/10.3310/hta16480} }