% alzhub.org library filter % Source: https://alzhub.org/research?category=inflammation&year=2021 % 44 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{cristaldi2022-34979121, author = {Cristaldi, A. and Fiore, M. and Oliveri Conti, G. and Pulvirenti, E. and Favara, C. and Grasso, A. and Copat, C. and Ferrante, M.}, title = {{Possible association between PM2.5 and neurodegenerative diseases: A systematic review}}, journal = {Environmental research}, year = {2022}, doi = {10.1016/j.envres.2021.112581}, pmid = {34979121}, url = {https://doi.org/10.1016/j.envres.2021.112581} } @article{damesquita2021-33911285, author = {Da Mesquita, S. and Papadopoulos, Z. and Dykstra, T. and Brase, L. and Farias, F. G. and Wall, M. and Jiang, H. and Kodira, C. D. and others}, title = {{Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy}}, journal = {Nature}, year = {2021}, doi = {10.1038/s41586-021-03489-0}, pmid = {33911285}, url = {https://doi.org/10.1038/s41586-021-03489-0} } @article{gerrits2021-33609158, author = {Gerrits, E. and Brouwer, N. and Kooistra, S. M. and Woodbury, M. E. and Vermeiren, Y. and Lambourne, M. and Mulder, J. and Kummer, M. and others}, title = {{Distinct amyloid-β and tau-associated microglia profiles in Alzheimer's disease}}, journal = {Acta neuropathologica}, year = {2021}, doi = {10.1007/s00401-021-02263-w}, pmid = {33609158}, url = {https://doi.org/10.1007/s00401-021-02263-w} } @article{mcalpine2021-33395100, author = {McAlpine, L. S. and Fesharaki-Zadeh, A. and Spudich, S.}, title = {{Coronavirus disease 2019 and neurodegenerative disease: what will the future bring?}}, journal = {Current opinion in psychiatry}, year = {2021}, doi = {10.1097/yco.0000000000000688}, pmid = {33395100}, url = {https://doi.org/10.1097/yco.0000000000000688} } @article{neff2021-33523961, author = {Neff, R. A. and Wang, M. and Vatansever, S. and Guo, L. and Ming, C. and Wang, Q. and Wang, E. and Horgusluoglu-Moloch, E. and others}, title = {{Molecular subtyping of Alzheimer's disease using RNA sequencing data reveals novel mechanisms and targets}}, journal = {Science advances}, year = {2021}, doi = {10.1126/sciadv.abb5398}, pmid = {33523961}, url = {https://doi.org/10.1126/sciadv.abb5398} } @article{szebenyi2021-34675437, author = {Szebényi, K. and Wenger, L. M. D. and Sun, Y. and Dunn, A. W. E. and Limegrover, C. A. and Gibbons, G. M. and Conci, E. and Paulsen, O. and others}, title = {{Human ALS/FTD brain organoid slice cultures display distinct early astrocyte and targetable neuronal pathology}}, journal = {Nature neuroscience}, year = {2021}, doi = {10.1038/s41593-021-00923-4}, pmid = {34675437}, url = {https://doi.org/10.1038/s41593-021-00923-4} } @article{logan2021-34450028, author = {Logan, T. and Simon, M. J. and Rana, A. and Cherf, G. M. and Srivastava, A. and Davis, S. S. and Low, R. L. Y. and Chiu, C. L. and others}, title = {{Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic}}, journal = {Cell}, year = {2021}, doi = {10.1016/j.cell.2021.08.002}, pmid = {34450028}, url = {https://doi.org/10.1016/j.cell.2021.08.002} } @article{terrerosroncal2021-34672693, author = {Terreros-Roncal, J. and Moreno-Jiménez, E. P. and Flor-García, M. and Rodríguez-Moreno, C. B. and Trinchero, M. F. and Cafini, F. and Rábano, A. and Llorens-Martín, M.}, title = {{Impact of neurodegenerative diseases on human adult hippocampal neurogenesis}}, journal = {Science (New York, N.Y.)}, year = {2021}, doi = {10.1126/science.abl5163}, pmid = {34672693}, url = {https://doi.org/10.1126/science.abl5163} } @article{dhapola2021-34813026, author = {Dhapola, R. and Hota, S. S. and Sarma, P. and Bhattacharyya, A. and Medhi, B. and Reddy, D. H.}, title = {{Recent advances in molecular pathways and therapeutic implications targeting neuroinflammation for Alzheimer's disease}}, journal = {Inflammopharmacology}, year = {2021}, doi = {10.1007/s10787-021-00889-6}, pmid = {34813026}, url = {https://doi.org/10.1007/s10787-021-00889-6} } @article{zhang2021-34551326, author = {Zhang, Z. and Yang, X. and Song, Y. Q. and Tu, J.}, title = {{Autophagy in Alzheimer's disease pathogenesis: Therapeutic potential and future perspectives}}, journal = {Ageing research reviews}, year = {2021}, doi = {10.1016/j.arr.2021.101464}, pmid = {34551326}, url = {https://doi.org/10.1016/j.arr.2021.101464} } @article{zhao2021-34530866, author = {Zhao, Y. and Zhang, J. and Zheng, Y. and Zhang, Y. and Zhang, X. J. and Wang, H. and Du, Y. and Guan, J. and others}, title = {{NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway}}, journal = {Journal of neuroinflammation}, year = {2021}, doi = {10.1186/s12974-021-02250-8}, pmid = {34530866}, url = {https://doi.org/10.1186/s12974-021-02250-8} } @article{propson2021-32990682, author = {Propson, N. E. and Roy, E. R. and Litvinchuk, A. and Köhl, J. and Zheng, H.}, title = {{Endothelial C3a receptor mediates vascular inflammation and blood-brain barrier permeability during aging}}, journal = {The Journal of clinical investigation}, year = {2021}, doi = {10.1172/jci140966}, pmid = {32990682}, url = {https://doi.org/10.1172/jci140966} } @article{park2021-33902708, author = {Park, J. S. and Kam, T. I. and Lee, S. and Park, H. and Oh, Y. and Kwon, S. H. and Song, J. J. and Kim, D. and others}, title = {{Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer's disease}}, journal = {Acta neuropathologica communications}, year = {2021}, doi = {10.1186/s40478-021-01180-z}, pmid = {33902708}, url = {https://doi.org/10.1186/s40478-021-01180-z} } @article{estebandeantonio2021-34420953, author = {Esteban de Antonio, E. and Pérez-Cordón, A. and Gil, S. and Orellana, A. and Cano, A. and Alegret, M. and Espinosa, A. and Alarcón-Martín, E. and others}, title = {{BIOFACE: A Prospective Study of Risk Factors, Cognition, and Biomarkers in a Cohort of Individuals with Early-Onset Mild Cognitive Impairment. Study Rationale and Research Protocols}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2021}, doi = {10.3233/jad-210254}, pmid = {34420953}, url = {https://doi.org/10.3233/jad-210254} } @article{gaikwad2021-34289368, author = {Gaikwad, S. and Puangmalai, N. and Bittar, A. and Montalbano, M. and Garcia, S. and McAllen, S. and Bhatt, N. and Sonawane, M. and others}, title = {{Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer's disease and frontotemporal dementia}}, journal = {Cell reports}, year = {2021}, doi = {10.1016/j.celrep.2021.109419}, pmid = {34289368}, url = {https://doi.org/10.1016/j.celrep.2021.109419} } @article{chen2021-33680283, author = {Chen, H. L. and Chen, P. C. and Lu, C. H. and Tsai, N. W. and Yu, C. C. and Chou, K. H. and Lai, Y. R. and Taoka, T. and others}, title = {{Associations among Cognitive Functions, Plasma DNA, and Diffusion Tensor Image along the Perivascular Space (DTI-ALPS) in Patients with Parkinson's Disease}}, journal = {Oxidative medicine and cellular longevity}, year = {2021}, doi = {10.1155/2021/4034509}, pmid = {33680283}, url = {https://doi.org/10.1155/2021/4034509} } @article{preman2021-33806259, author = {Preman, P. and Alfonso-Triguero, M. and Alberdi, E. and Verkhratsky, A. and Arranz, A. M.}, title = {{Astrocytes in Alzheimer's Disease: Pathological Significance and Molecular Pathways}}, journal = {Cells}, year = {2021}, doi = {10.3390/cells10030540}, pmid = {33806259}, url = {https://doi.org/10.3390/cells10030540} } @article{kenkhuis2021-33597025, author = {Kenkhuis, B. and Somarakis, A. and de Haan, L. and Dzyubachyk, O. and IJsselsteijn, M. E. and de Miranda, N. F. C. C. and Lelieveldt, B. P. F. and Dijkstra, J. and others}, title = {{Iron loading is a prominent feature of activated microglia in Alzheimer's disease patients}}, journal = {Acta neuropathologica communications}, year = {2021}, doi = {10.1186/s40478-021-01126-5}, pmid = {33597025}, url = {https://doi.org/10.1186/s40478-021-01126-5} } @article{shahidehpour2021-33422891, author = {Shahidehpour, R. K. and Higdon, R. E. and Crawford, N. G. and Neltner, J. H. and Ighodaro, E. T. and Patel, E. and Price, D. and Nelson, P. T. and others}, title = {{Dystrophic microglia are associated with neurodegenerative disease and not healthy aging in the human brain}}, journal = {Neurobiology of aging}, year = {2021}, doi = {10.1016/j.neurobiolaging.2020.12.003}, pmid = {33422891}, url = {https://doi.org/10.1016/j.neurobiolaging.2020.12.003} } @article{lopezrodriguez2021-34080771, author = {Lopez-Rodriguez, Ana Belen and Hennessy, Edel and Murray, Carol L and Nazmi, Arshed and Delaney, Hugh J and Healy, Dáire and Fagan, Steven G and Rooney, Michael and others}, title = {{Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL-1β drives amplified responses in primed astrocytes and neuronal network dysfunction}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2021}, doi = {10.1002/alz.12341}, pmid = {34080771}, url = {https://doi.org/10.1002/alz.12341} } @article{kim2021-33382892, author = {Kim, Jong-Heon and Afridi, Ruqayya and Han, Jin and Jung, Hyun-Gug and Kim, Seung-Chan and Hwang, Eun Mi and Shim, Hyun Soo and Ryu, Hoon and others}, title = {{Gamma subunit of complement component 8 is a neuroinflammation inhibitor}}, journal = {Brain : a journal of neurology}, year = {2021}, doi = {10.1093/brain/awaa425}, pmid = {33382892}, url = {https://doi.org/10.1093/brain/awaa425} } @article{price2021-33812051, author = {Price, B. R. and Johnson, L. A. and Norris, C. M.}, title = {{Reactive astrocytes: The nexus of pathological and clinical hallmarks of Alzheimer's disease}}, journal = {Ageing research reviews}, year = {2021}, doi = {10.1016/j.arr.2021.101335}, pmid = {33812051}, url = {https://doi.org/10.1016/j.arr.2021.101335} } @article{shabbir2021-33669988, author = {Shabbir, U. and Arshad, M. S. and Sameen, A. and Oh, D. H.}, title = {{Crosstalk between Gut and Brain in Alzheimer's Disease: The Role of Gut Microbiota Modulation Strategies}}, journal = {Nutrients}, year = {2021}, doi = {10.3390/nu13020690}, pmid = {33669988}, url = {https://doi.org/10.3390/nu13020690} } @article{zhou2021-34108016, author = {Zhou, Y. and Xu, J. and Hou, Y. and Leverenz, J. B. and Kallianpur, A. and Mehra, R. and Liu, Y. and Yu, H. and others}, title = {{Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment}}, journal = {Alzheimer's research \& therapy}, year = {2021}, doi = {10.1186/s13195-021-00850-3}, pmid = {34108016}, url = {https://doi.org/10.1186/s13195-021-00850-3} } @article{zhang2021-34239348, author = {Zhang, Huiqin and Wei, Wei and Zhao, Ming and Ma, Lina and Jiang, Xuefan and Pei, Hui and Cao, Yu and Li, Hao}, title = {{Interaction between Aβ and Tau in the Pathogenesis of Alzheimer's Disease}}, journal = {International Journal of Biological Sciences}, year = {2021}, doi = {10.7150/ijbs.57078}, pmid = {34239348}, url = {https://doi.org/10.7150/ijbs.57078} } @article{hou2021-34497121, author = {Hou, Yujun and Wei, Yong and Lautrup, Sofie and Yang, Beimeng and Wang, Yue and Cordonnier, Stephanie and Mattson, Mark P and Croteau, Deborah L and others}, title = {{NAD+ supplementation reduces neuroinflammation and cell senescence in a transgenic mouse model of Alzheimer's disease via cGAS-STING}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2021}, doi = {10.1073/pnas.2011226118}, pmid = {34497121}, url = {https://doi.org/10.1073/pnas.2011226118} } @article{kim2021-34638977, author = {Kim, Jieun and Lee, Hyun-Ju and Park, Seon Kyeong and Park, Jin-Hee and Jeong, Ha-Ram and Lee, Soojung and Lee, Heeyong and Seol, Eunyoung and others}, title = {{Donepezil Regulates LPS and Aβ-Stimulated Neuroinflammation through MAPK/NLRP3 Inflammasome/STAT3 Signaling}}, journal = {International journal of molecular sciences}, year = {2021}, doi = {10.3390/ijms221910637}, pmid = {34638977}, url = {https://doi.org/10.3390/ijms221910637} } @article{shah2021-34948444, author = {Shah, Akash and Kishore, Uday and Shastri, Abhishek}, title = {{Complement System in Alzheimer's Disease}}, journal = {International journal of molecular sciences}, year = {2021}, doi = {10.3390/ijms222413647}, pmid = {34948444}, url = {https://doi.org/10.3390/ijms222413647} } @article{he2021-34229722, author = {He, Xiao-Fei and Li, Li-Li and Xian, Wen-Biao and Li, Ming-Yue and Zhang, Li-Ying and Xu, Jing-Hui and Pei, Zhong and Zheng, Hai-Qing and others}, title = {{Chronic colitis exacerbates NLRP3-dependent neuroinflammation and cognitive impairment in middle-aged brain}}, journal = {Journal of neuroinflammation}, year = {2021}, doi = {10.1186/s12974-021-02199-8}, pmid = {34229722}, url = {https://doi.org/10.1186/s12974-021-02199-8} } @article{vanzeller2021-34366341, author = {Van Zeller, Mariana and Dias, Diogo and Sebastião, Ana M and Valente, Cláudia A}, title = {{NLRP3 Inflammasome: A Starring Role in Amyloid-β- and Tau-Driven Pathological Events in Alzheimer's Disease}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2021}, doi = {10.3233/jad-210268}, pmid = {34366341}, url = {https://doi.org/10.3233/jad-210268} } @article{ravichandran2021-34846519, author = {Ravichandran, Kishore Aravind and Heneka, Michael T}, title = {{Inflammasome activation in neurodegenerative diseases}}, journal = {Essays in biochemistry}, year = {2021}, doi = {10.1042/ebc20210021}, pmid = {34846519}, url = {https://doi.org/10.1042/ebc20210021} } @article{holbrook2021-33776778, author = {Holbrook, Jonathan A and Jarosz-Griffiths, Heledd H and Caseley, Emily and Lara-Reyna, Samuel and Poulter, James A and Williams-Gray, Caroline H and Peckham, Daniel and McDermott, Michael F}, title = {{Neurodegenerative Disease and the NLRP3 Inflammasome}}, journal = {Frontiers in pharmacology}, year = {2021}, doi = {10.3389/fphar.2021.643254}, pmid = {33776778}, url = {https://doi.org/10.3389/fphar.2021.643254} } @article{rather2021-34381308, author = {Rather, Mashoque Ahmad and Khan, Andleeb and Alshahrani, Saeed and Rashid, Hina and Qadri, Marwa and Rashid, Summya and Alsaffar, Rana M and Kamal, Mohammad Amjad and others}, title = {{Inflammation and Alzheimer's Disease: Mechanisms and Therapeutic Implications by Natural Products}}, journal = {Mediators of inflammation}, year = {2021}, doi = {10.1155/2021/9982954}, pmid = {34381308}, url = {https://doi.org/10.1155/2021/9982954} } @article{zhang2021-34430820, author = {Zhang, Liansheng and Qian, Yun and Li, Jie and Zhou, Xuan and Xu, He and Yan, Jie and Xiang, Jialing and Yuan, Xiang and others}, title = {{BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology}}, journal = {iScience}, year = {2021}, doi = {10.1016/j.isci.2021.102942}, pmid = {34430820}, url = {https://doi.org/10.1016/j.isci.2021.102942} } @article{lee2021-34668411, author = {Lee, SangJoon and Cho, Hyun-Jeong and Ryu, Jin-Hyeob}, title = {{Innate Immunity and Cell Death in Alzheimer's Disease}}, journal = {ASN neuro}, year = {2021}, doi = {10.1177/17590914211051908}, pmid = {34668411}, url = {https://doi.org/10.1177/17590914211051908} } @article{toscano2021-34530705, author = {Toscano, Eliana C de Brito and Rocha, Natalia P and Lopes, Beatriz N A and Suemoto, Claudia K and Teixeira, Antonio L}, title = {{Neuroinflammation in Alzheimer's Disease: Focus on NLRP1 and NLRP3 Inflammasomes}}, journal = {Current protein \& peptide science}, year = {2021}, doi = {10.2174/1389203722666210916141436}, pmid = {34530705}, url = {https://doi.org/10.2174/1389203722666210916141436} } @article{sandhu2021-33499208, author = {Sandhu, Jagdeep K and Kulka, Marianna}, title = {{Decoding Mast Cell-Microglia Communication in Neurodegenerative Diseases}}, journal = {International journal of molecular sciences}, year = {2021}, doi = {10.3390/ijms22031093}, pmid = {33499208}, url = {https://doi.org/10.3390/ijms22031093} } @article{trudler2021-33833060, author = {Trudler, Dorit and Nazor, Kristopher L and Eisele, Yvonne S and Grabauskas, Titas and Dolatabadi, Nima and Parker, James and Sultan, Abdullah and Zhong, Zhenyu and others}, title = {{Soluble α-synuclein-antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2021}, doi = {10.1073/pnas.2025847118}, pmid = {33833060}, url = {https://doi.org/10.1073/pnas.2025847118} } @article{lei2021-33641782, author = {Lei, Li-Yan and Wang, Rui-Cheng and Pan, Ya-Lei and Yue, Zheng-Gang and Zhou, Rui and Xie, Pei and Tang, Zhi-Shu}, title = {{Mangiferin inhibited neuroinflammation through regulating microglial polarization and suppressing NF-κB, NLRP3 pathway}}, journal = {Chinese journal of natural medicines}, year = {2021}, doi = {10.1016/s1875-5364(21)60012-2}, pmid = {33641782}, url = {https://doi.org/10.1016/s1875-5364(21)60012-2} } @article{shukla2021-33916001, author = {Shukla, Pradeep K and Delotterie, David F and Xiao, Jianfeng and Pierre, Joseph F and Rao, RadhaKrishna and McDonald, Michael P and Khan, Mohammad Moshahid}, title = {{Alterations in the Gut-Microbial-Inflammasome-Brain Axis in a Mouse Model of Alzheimer's Disease}}, journal = {Cells}, year = {2021}, doi = {10.3390/cells10040779}, pmid = {33916001}, url = {https://doi.org/10.3390/cells10040779} } @article{xu2021-34187889, author = {Xu, Yin and Propson, Nicholas E and Du, Shuqi and Xiong, Wen and Zheng, Hui}, title = {{Autophagy deficiency modulates microglial lipid homeostasis and aggravates tau pathology and spreading}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2021}, doi = {10.1073/pnas.2023418118}, pmid = {34187889}, url = {https://doi.org/10.1073/pnas.2023418118} } @article{golzarisorkheh2021-34569958, author = {Golzari-Sorkheh, Mahdieh and Brown, Carla E and Weaver, Donald F and Reed, Mark A}, title = {{The NLRP3 Inflammasome in the Pathogenesis and Treatment of Alzheimer's Disease}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2021}, doi = {10.3233/jad-210660}, pmid = {34569958}, url = {https://doi.org/10.3233/jad-210660} } @article{sita2021-34209586, author = {Sita, Giulia and Graziosi, Agnese and Hrelia, Patrizia and Morroni, Fabiana}, title = {{NLRP3 and Infections: β-Amyloid in Inflammasome beyond Neurodegeneration}}, journal = {International journal of molecular sciences}, year = {2021}, doi = {10.3390/ijms22136984}, pmid = {34209586}, url = {https://doi.org/10.3390/ijms22136984} } @article{ghosh2021-34656693, author = {Ghosh, Powsali and Singh, Ravi and Ganeshpurkar, Ankit and Pokle, Ankit Vyankatrao and Singh, Ravi Bhushan and Singh, Sushil Kumar and Kumar, Ashok}, title = {{Cellular and molecular influencers of neuroinflammation in Alzheimer's disease: Recent concepts \& roles}}, journal = {Neurochemistry international}, year = {2021}, doi = {10.1016/j.neuint.2021.105212}, pmid = {34656693}, url = {https://doi.org/10.1016/j.neuint.2021.105212} }