% alzhub.org library filter
% Source: https://alzhub.org/research?category=genetics_trem2&year=2016
% 42 entries, in the order the page lists them. Built from alzhub.org's own records.
% 0 entries have no readable author in the source record and carry no author field.

@article{carrasquillo2017-27939925,
  author  = {Carrasquillo, M. M. and Allen, M. and Burgess, J. D. and Wang, X. and Strickland, S. L. and Aryal, S. and Siuda, J. and Kachadoorian, M. L. and others},
  title   = {{A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2017},
  doi     = {10.1016/j.jalz.2016.10.005},
  pmid    = {27939925},
  url     = {https://doi.org/10.1016/j.jalz.2016.10.005}
}

@article{wang2016-27091843,
  author  = {Wang, Y. and Ulland, T. K. and Ulrich, J. D. and Song, W. and Tzaferis, J. A. and Hole, J. T. and Yuan, P. and Mahan, T. E. and others},
  title   = {{TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques}},
  journal = {The Journal of experimental medicine},
  year    = {2016},
  doi     = {10.1084/jem.20151948},
  pmid    = {27091843},
  url     = {https://doi.org/10.1084/jem.20151948}
}

@article{suarezcalvet2016-26941262,
  author  = {Suárez-Calvet, M. and Kleinberger, G. and MÁ, Araque Caballero and Brendel, M. and Rominger, A. and Alcolea, D. and Fortea, J. and Lleó, A. and others},
  title   = {{sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers}},
  journal = {EMBO molecular medicine},
  year    = {2016},
  doi     = {10.15252/emmm.201506123},
  pmid    = {26941262},
  url     = {https://doi.org/10.15252/emmm.201506123}
}

@article{heslegrave2016-26754172,
  author  = {Heslegrave, A. and Heywood, W. and Paterson, R. and Magdalinou, N. and Svensson, J. and Johansson, P. and Öhrfelt, A. and Blennow, K. and others},
  title   = {{Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer's disease}},
  journal = {Molecular neurodegeneration},
  year    = {2016},
  doi     = {10.1186/s13024-016-0071-x},
  pmid    = {26754172},
  url     = {https://doi.org/10.1186/s13024-016-0071-x}
}

@article{yuan2016-27196974,
  author  = {Yuan, P. and Condello, C. and Keene, C. D. and Wang, Y. and Bird, T. D. and Paul, S. M. and Luo, W. and Colonna, M. and others},
  title   = {{TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy}},
  journal = {Neuron},
  year    = {2016},
  doi     = {10.1016/j.neuron.2016.05.003},
  pmid    = {27196974},
  url     = {https://doi.org/10.1016/j.neuron.2016.05.003}
}

@article{lupton2016-26973105,
  author  = {Lupton, M. K. and Strike, L. and Hansell, N. K. and Wen, W. and Mather, K. A. and Armstrong, N. J. and Thalamuthu, A. and McMahon, K. L. and others},
  title   = {{The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume}},
  journal = {Neurobiology of aging},
  year    = {2016},
  doi     = {10.1016/j.neurobiolaging.2015.12.023},
  pmid    = {26973105},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2015.12.023}
}

@article{smith2016-27522519,
  author  = {Smith, A. R. and Smith, R. G. and Condliffe, D. and Hannon, E. and Schalkwyk, L. and Mill, J. and Lunnon, K.},
  title   = {{Increased DNA methylation near TREM2 is consistently seen in the superior temporal gyrus in Alzheimer's disease brain}},
  journal = {Neurobiology of aging},
  year    = {2016},
  doi     = {10.1016/j.neurobiolaging.2016.07.008},
  pmid    = {27522519},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2016.07.008}
}

@article{yeh2016-27477018,
  author  = {Yeh, F. L. and Wang, Y. and Tom, I. and Gonzalez, L. C. and Sheng, M.},
  title   = {{TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia}},
  journal = {Neuron},
  year    = {2016},
  doi     = {10.1016/j.neuron.2016.06.015},
  pmid    = {27477018},
  url     = {https://doi.org/10.1016/j.neuron.2016.06.015}
}

@article{song2017-27520774,
  author  = {Song, W. and Hooli, B. and Mullin, K. and Jin, S. C. and Cella, M. and Ulland, T. K. and Wang, Y. and Tanzi, R. E. and others},
  title   = {{Alzheimer's disease-associated TREM2 variants exhibit either decreased or increased ligand-dependent activation}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2017},
  doi     = {10.1016/j.jalz.2016.07.004},
  pmid    = {27520774},
  url     = {https://doi.org/10.1016/j.jalz.2016.07.004}
}

@article{henjum2016-27121148,
  author  = {Henjum, K. and Almdahl, I. S. and Årskog, V. and Minthon, L. and Hansson, O. and Fladby, T. and Nilsson, L. N.},
  title   = {{Cerebrospinal fluid soluble TREM2 in aging and Alzheimer's disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2016},
  doi     = {10.1186/s13195-016-0182-1},
  pmid    = {27121148},
  url     = {https://doi.org/10.1186/s13195-016-0182-1}
}

@article{bisht2016-26847266,
  author  = {Bisht, K. and Sharma, K. P. and Lecours, C. and Sánchez, M. G. and El Hajj, H. and Milior, G. and Olmos-Alonso, A. and Gómez-Nicola, D. and others},
  title   = {{Dark microglia: A new phenotype predominantly associated with pathological states}},
  journal = {Glia},
  year    = {2016},
  doi     = {10.1002/glia.22966},
  pmid    = {26847266},
  url     = {https://doi.org/10.1002/glia.22966}
}

@article{ridge2016-27036079,
  author  = {Ridge, P. G. and Hoyt, K. B. and Boehme, K. and Mukherjee, S. and Crane, P. K. and Haines, J. L. and Mayeux, R. and Farrer, L. A. and others},
  title   = {{Assessment of the genetic variance of late-onset Alzheimer's disease}},
  journal = {Neurobiology of aging},
  year    = {2016},
  doi     = {10.1016/j.neurobiolaging.2016.02.024},
  pmid    = {27036079},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2016.02.024}
}

@article{jiang2016-27501831,
  author  = {Jiang, T. and Hou, J. K. and Gao, Q. and Yu, J. T. and Zhou, J. S. and Zhao, H. D. and Zhang, Y. D.},
  title   = {{TREM2 p.H157Y Variant and the Risk of Alzheimer's Disease: A Meta-Analysis Involving 14,510 Subjects}},
  journal = {Current neurovascular research},
  year    = {2016},
  doi     = {10.2174/1567202613666160808095530},
  pmid    = {27501831},
  url     = {https://doi.org/10.2174/1567202613666160808095530}
}

@article{cuyvers2016-27302364,
  author  = {Cuyvers, E. and Sleegers, K.},
  title   = {{Genetic variations underlying Alzheimer's disease: evidence from genome-wide association studies and beyond}},
  journal = {The Lancet. Neurology},
  year    = {2016},
  doi     = {10.1016/s1474-4422(16)00127-7},
  pmid    = {27302364},
  url     = {https://doi.org/10.1016/s1474-4422(16)00127-7}
}

@article{kober2016-27995897,
  author  = {Kober, D. L. and Alexander-Brett, J. M. and Karch, C. M. and Cruchaga, C. and Colonna, M. and Holtzman, M. J. and Brett, T. J.},
  title   = {{Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms}},
  journal = {eLife},
  year    = {2016},
  doi     = {10.7554/elife.20391},
  pmid    = {27995897},
  url     = {https://doi.org/10.7554/elife.20391}
}

@article{gispert2016-27423963,
  author  = {Gispert, J. D. and Suárez-Calvet, M. and Monté, G. C. and Tucholka, A. and Falcon, C. and Rojas, S. and Rami, L. and Sánchez-Valle, R. and others},
  title   = {{Cerebrospinal fluid sTREM2 levels are associated with gray matter volume increases and reduced diffusivity in early Alzheimer's disease}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2016},
  doi     = {10.1016/j.jalz.2016.06.005},
  pmid    = {27423963},
  url     = {https://doi.org/10.1016/j.jalz.2016.06.005}
}

@article{bhattacharjee2016-26949937,
  author  = {Bhattacharjee, S. and Zhao, Y. and Dua, P. and Rogaev, E. I. and Lukiw, W. J.},
  title   = {{microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration}},
  journal = {PloS one},
  year    = {2016},
  doi     = {10.1371/journal.pone.0150211},
  pmid    = {26949937},
  url     = {https://doi.org/10.1371/journal.pone.0150211}
}

@article{ohrfelt2016-26754805,
  author  = {Öhrfelt, A. and Axelsson, M. and Malmeström, C. and Novakova, L. and Heslegrave, A. and Blennow, K. and Lycke, J. and Zetterberg, H.},
  title   = {{Soluble TREM-2 in cerebrospinal fluid from patients with multiple sclerosis treated with natalizumab or mitoxantrone}},
  journal = {Multiple sclerosis (Houndmills, Basingstoke, England)},
  year    = {2016},
  doi     = {10.1177/1352458515624558},
  pmid    = {26754805},
  url     = {https://doi.org/10.1177/1352458515624558}
}

@article{jiang2016-27067662,
  author  = {Jiang, T. and Tan, L. and Chen, Q. and Tan, M. S. and Zhou, J. S. and Zhu, X. C. and Lu, H. and Wang, H. F. and others},
  title   = {{A rare coding variant in TREM2 increases risk for Alzheimer's disease in Han Chinese}},
  journal = {Neurobiology of aging},
  year    = {2016},
  doi     = {10.1016/j.neurobiolaging.2016.02.023},
  pmid    = {27067662},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2016.02.023}
}

@article{xiang2016-27402340,
  author  = {Xiang, X. and Werner, G. and Bohrmann, B. and Liesz, A. and Mazaheri, F. and Capell, A. and Feederle, R. and Knuesel, I. and others},
  title   = {{TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance}},
  journal = {EMBO molecular medicine},
  year    = {2016},
  doi     = {10.15252/emmm.201606370},
  pmid    = {27402340},
  url     = {https://doi.org/10.15252/emmm.201606370}
}

@article{jiang2016-26802771,
  author  = {Jiang, T. and Zhang, Y. D. and Chen, Q. and Gao, Q. and Zhu, X. C. and Zhou, J. S. and Shi, J. Q. and Lu, H. and others},
  title   = {{TREM2 modifies microglial phenotype and provides neuroprotection in P301S tau transgenic mice}},
  journal = {Neuropharmacology},
  year    = {2016},
  doi     = {10.1016/j.neuropharm.2016.01.028},
  pmid    = {26802771},
  url     = {https://doi.org/10.1016/j.neuropharm.2016.01.028}
}

@article{kobayashi2016-27798193,
  author  = {Kobayashi, M. and Konishi, H. and Sayo, A. and Takai, T. and Kiyama, H.},
  title   = {{TREM2/DAP12 Signal Elicits Proinflammatory Response in Microglia and Exacerbates Neuropathic Pain}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2016},
  doi     = {10.1523/jneurosci.1238-16.2016},
  pmid    = {27798193},
  url     = {https://doi.org/10.1523/jneurosci.1238-16.2016}
}

@article{zheng2016-27143430,
  author  = {Zheng, H. and Liu, C. C. and Atagi, Y. and Chen, X. F. and Jia, L. and Yang, L. and He, W. and Zhang, X. and others},
  title   = {{Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation}},
  journal = {Neurobiology of aging},
  year    = {2016},
  doi     = {10.1016/j.neurobiolaging.2016.03.004},
  pmid    = {27143430},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2016.03.004}
}

@article{graham2016-26888450,
  author  = {Graham, L. C. and Harder, J. M. and Soto, I. and de Vries, W. N. and John, S. W. and Howell, G. R.},
  title   = {{Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer's disease}},
  journal = {Scientific reports},
  year    = {2016},
  doi     = {10.1038/srep21568},
  pmid    = {26888450},
  url     = {https://doi.org/10.1038/srep21568}
}

@article{ulrich2016-26854967,
  author  = {Ulrich, J. D. and Holtzman, D. M.},
  title   = {{TREM2 Function in Alzheimer's Disease and Neurodegeneration}},
  journal = {ACS chemical neuroscience},
  year    = {2016},
  doi     = {10.1021/acschemneuro.5b00313},
  pmid    = {26854967},
  url     = {https://doi.org/10.1021/acschemneuro.5b00313}
}

@article{baizabalcarvallo2016-26891767,
  author  = {Baizabal-Carvallo, J. F. and Jankovic, J.},
  title   = {{Parkinsonism, movement disorders and genetics in frontotemporal dementia}},
  journal = {Nature reviews. Neurology},
  year    = {2016},
  doi     = {10.1038/nrneurol.2016.14},
  pmid    = {26891767},
  url     = {https://doi.org/10.1038/nrneurol.2016.14}
}

@article{mohle2016-26984535,
  author  = {Möhle, L. and Israel, N. and Paarmann, K. and Krohn, M. and Pietkiewicz, S. and Müller, A. and Lavrik, I. N. and Buguliskis, J. S. and others},
  title   = {{Chronic Toxoplasma gondii infection enhances β-amyloid phagocytosis and clearance by recruited monocytes}},
  journal = {Acta neuropathologica communications},
  year    = {2016},
  doi     = {10.1186/s40478-016-0293-8},
  pmid    = {26984535},
  url     = {https://doi.org/10.1186/s40478-016-0293-8}
}

@article{pottier2016-27658901,
  author  = {Pottier, C. and Ravenscroft, T. A. and Brown, P. H. and Finch, N. A. and Baker, M. and Parsons, M. and Asmann, Y. W. and Ren, Y. and others},
  title   = {{TYROBP genetic variants in early-onset Alzheimer's disease}},
  journal = {Neurobiology of aging},
  year    = {2016},
  doi     = {10.1016/j.neurobiolaging.2016.07.028},
  pmid    = {27658901},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2016.07.028}
}

@article{wes2016-27100611,
  author  = {Wes, P. D. and Sayed, F. A. and Bard, F. and Gan, L.},
  title   = {{Targeting microglia for the treatment of Alzheimer's Disease}},
  journal = {Glia},
  year    = {2016},
  doi     = {10.1002/glia.22988},
  pmid    = {27100611},
  url     = {https://doi.org/10.1002/glia.22988}
}

@article{hamerman2016-26683155,
  author  = {Hamerman, J. A. and Pottle, J. and Ni, M. and He, Y. and Zhang, Z. Y. and Buckner, J. H.},
  title   = {{Negative regulation of TLR signaling in myeloid cells--implications for autoimmune diseases}},
  journal = {Immunological reviews},
  year    = {2016},
  doi     = {10.1111/imr.12381},
  pmid    = {26683155},
  url     = {https://doi.org/10.1111/imr.12381}
}

@article{saber2017-26976047,
  author  = {Saber, M. and Kokiko-Cochran, O. and Puntambekar, S. S. and Lathia, J. D. and Lamb, B. T.},
  title   = {{Triggering Receptor Expressed on Myeloid Cells 2 Deficiency Alters Acute Macrophage Distribution and Improves Recovery after Traumatic Brain Injury}},
  journal = {Journal of neurotrauma},
  year    = {2017},
  doi     = {10.1089/neu.2016.4401},
  pmid    = {26976047},
  url     = {https://doi.org/10.1089/neu.2016.4401}
}

@article{celarain2016-27051467,
  author  = {Celarain, N. and Sánchez-Ruiz de Gordoa, J. and Zelaya, M. V. and Roldán, M. and Larumbe, R. and Pulido, L. and Echavarri, C. and Mendioroz, M.},
  title   = {{TREM2 upregulation correlates with 5-hydroxymethycytosine enrichment in Alzheimer's disease hippocampus}},
  journal = {Clinical epigenetics},
  year    = {2016},
  doi     = {10.1186/s13148-016-0202-9},
  pmid    = {27051467},
  url     = {https://doi.org/10.1186/s13148-016-0202-9}
}

@article{sirkis2016-27589997,
  author  = {Sirkis, D. W. and Bonham, L. W. and Aparicio, R. E. and Geier, E. G. and Ramos, E. M. and Wang, Q. and Karydas, A. and Miller, Z. A. and others},
  title   = {{Rare TREM2 variants associated with Alzheimer's disease display reduced cell surface expression}},
  journal = {Acta neuropathologica communications},
  year    = {2016},
  doi     = {10.1186/s40478-016-0367-7},
  pmid    = {27589997},
  url     = {https://doi.org/10.1186/s40478-016-0367-7}
}

@article{dorszewska2016-26971934,
  author  = {Dorszewska, J. and Prendecki, M. and Oczkowska, A. and Dezor, M. and Kozubski, W.},
  title   = {{Molecular Basis of Familial and Sporadic Alzheimer's Disease}},
  journal = {Current Alzheimer research},
  year    = {2016},
  doi     = {10.2174/1567205013666160314150501},
  pmid    = {26971934},
  url     = {https://doi.org/10.2174/1567205013666160314150501}
}

@article{yin2016-27717139,
  author  = {Yin, J. and Liu, X. and He, Q. and Zhou, L. and Yuan, Z. and Zhao, S.},
  title   = {{Vps35-dependent recycling of Trem2 regulates microglial function}},
  journal = {Traffic (Copenhagen, Denmark)},
  year    = {2016},
  doi     = {10.1111/tra.12451},
  pmid    = {27717139},
  url     = {https://doi.org/10.1111/tra.12451}
}

@article{wang2016-26506595,
  author  = {Wang, X. Q. and Tao, B. B. and Li, B. and Wang, X. H. and Zhang, W. C. and Wan, L. and Hua, X. M. and Li, S. T.},
  title   = {{Overexpression of TREM2 enhances glioma cell proliferation and invasion: a therapeutic target in human glioma}},
  journal = {Oncotarget},
  year    = {2016},
  doi     = {10.18632/oncotarget.6221},
  pmid    = {26506595},
  url     = {https://doi.org/10.18632/oncotarget.6221}
}

@article{sasaki2017-27859676,
  author  = {Sasaki, A.},
  title   = {{Microglia and brain macrophages: An update}},
  journal = {Neuropathology : official journal of the Japanese Society of Neuropathology},
  year    = {2017},
  doi     = {10.1111/neup.12354},
  pmid    = {27859676},
  url     = {https://doi.org/10.1111/neup.12354}
}

@article{ma2016-27887626,
  author  = {Ma, L. and Allen, M. and Sakae, N. and Ertekin-Taner, N. and Graff-Radford, N. R. and Dickson, D. W. and Younkin, S. G. and Sevlever, D.},
  title   = {{Expression and processing analyses of wild type and p.R47H TREM2 variant in Alzheimer's disease brains}},
  journal = {Molecular neurodegeneration},
  year    = {2016},
  doi     = {10.1186/s13024-016-0137-9},
  pmid    = {27887626},
  url     = {https://doi.org/10.1186/s13024-016-0137-9}
}

@article{han2017-27871212,
  author  = {Han, Jie and Wang, Miaomiao and Ren, Manru and Lou, Haiyan},
  title   = {{Contributions of triggering-receptor-expressed-on-myeloid-cells-2 to neurological diseases}},
  journal = {The International journal of neuroscience},
  year    = {2017},
  doi     = {10.1080/00207454.2016.1264072},
  pmid    = {27871212},
  url     = {https://doi.org/10.1080/00207454.2016.1264072}
}

@article{jiang2017-26780455,
  author  = {Jiang, Teng and Wan, Yu and Zhang, Ying-Dong and Zhou, Jun-Shan and Gao, Qing and Zhu, Xi-Chen and Shi, Jian-Quan and Lu, Huan and others},
  title   = {{TREM2 Overexpression has No Improvement on Neuropathology and Cognitive Impairment in Aging APPswe/PS1dE9 Mice}},
  journal = {Molecular neurobiology},
  year    = {2017},
  doi     = {10.1007/s12035-016-9704-x},
  pmid    = {26780455},
  url     = {https://doi.org/10.1007/s12035-016-9704-x}
}

@article{humphrey2016-26573914,
  author  = {Humphrey, M. B. and Nakamura, M. C.},
  title   = {{A Comprehensive Review of Immunoreceptor Regulation of Osteoclasts}},
  journal = {Clinical reviews in allergy \& immunology},
  year    = {2016},
  doi     = {10.1007/s12016-015-8521-8},
  pmid    = {26573914},
  url     = {https://doi.org/10.1007/s12016-015-8521-8}
}

@article{glebov2016-26792193,
  author  = {Glebov, Konstantin and Wunderlich, Patrick and Karaca, Ilker and Walter, Jochen},
  title   = {{Functional involvement of γ-secretase in signaling of the triggering receptor expressed on myeloid cells-2 (TREM2)}},
  journal = {Journal of neuroinflammation},
  year    = {2016},
  doi     = {10.1186/s12974-016-0479-9},
  pmid    = {26792193},
  url     = {https://doi.org/10.1186/s12974-016-0479-9}
}