% alzhub.org library filter % Source: https://alzhub.org/research?category=genetics_trem2&institution=I79576946 % 21 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{sims2017-28714976, author = {Sims, R. and van der Lee, S. J. and Naj, A. C. and Bellenguez, C. and Badarinarayan, N. and Jakobsdottir, J. and Kunkle, B. W. and Boland, A. and others}, title = {{Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease}}, journal = {Nature genetics}, year = {2017}, doi = {10.1038/ng.3916}, pmid = {28714976}, url = {https://doi.org/10.1038/ng.3916} } @article{rajabli2025-40676597, author = {Rajabli, F. and Benchek, P. and Tosto, G. and Kushch, N. and Sha, J. and Bazemore, K. and Zhu, C. and Lee, W. P. and others}, title = {{Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease}}, journal = {Genome biology}, year = {2025}, doi = {10.1186/s13059-025-03564-z}, pmid = {40676597}, url = {https://doi.org/10.1186/s13059-025-03564-z} } @article{lill2015-25936935, author = {Lill, C. M. and Rengmark, A. and Pihlstrøm, L. and Fogh, I. and Shatunov, A. and Sleiman, P. M. and Wang, L. S. and Liu, T. and others}, title = {{The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2015}, doi = {10.1016/j.jalz.2014.12.009}, pmid = {25936935}, url = {https://doi.org/10.1016/j.jalz.2014.12.009} } @article{suarezcalvet2019-30630532, author = {Suárez-Calvet, M. and Morenas-Rodríguez, E. and Kleinberger, G. and Schlepckow, K. and MÁ, Araque Caballero and Franzmeier, N. and Capell, A. and Fellerer, K. and others}, title = {{Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-β pathology}}, journal = {Molecular neurodegeneration}, year = {2019}, doi = {10.1186/s13024-018-0301-5}, pmid = {30630532}, url = {https://doi.org/10.1186/s13024-018-0301-5} } @article{benitez2014-24439484, author = {Benitez, B. A. and Jin, S. C. and Guerreiro, R. and Graham, R. and Lord, J. and Harold, D. and Sims, R. and Lambert, J. C. and others}, title = {{Missense variant in TREML2 protects against Alzheimer's disease}}, journal = {Neurobiology of aging}, year = {2014}, doi = {10.1016/j.neurobiolaging.2013.12.010}, pmid = {24439484}, url = {https://doi.org/10.1016/j.neurobiolaging.2013.12.010} } @article{molinuevo2018-30488277, author = {Molinuevo, J. L. and Ayton, S. and Batrla, R. and Bednar, M. M. and Bittner, T. and Cummings, J. and Fagan, A. M. and Hampel, H. and others}, title = {{Current state of Alzheimer's fluid biomarkers}}, journal = {Acta neuropathologica}, year = {2018}, doi = {10.1007/s00401-018-1932-x}, pmid = {30488277}, url = {https://doi.org/10.1007/s00401-018-1932-x} } @article{franzmeier2020-33032659, author = {Franzmeier, N. and Suárez-Calvet, M. and Frontzkowski, L. and Moore, A. and Hohman, T. J. and Morenas-Rodriguez, E. and Nuscher, B. and Shaw, L. and others}, title = {{Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration}}, journal = {Molecular neurodegeneration}, year = {2020}, doi = {10.1186/s13024-020-00407-2}, pmid = {33032659}, url = {https://doi.org/10.1186/s13024-020-00407-2} } @article{jaitin2019-31257031, author = {Jaitin, D. A. and Adlung, L. and Thaiss, C. A. and Weiner, A. and Li, B. and Descamps, H. and Lundgren, P. and Bleriot, C. and others}, title = {{Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner}}, journal = {Cell}, year = {2019}, doi = {10.1016/j.cell.2019.05.054}, pmid = {31257031}, url = {https://doi.org/10.1016/j.cell.2019.05.054} } @article{bartl2021-34618817, author = {Bartl, M. and Dakna, M. and Galasko, D. and Hutten, S. J. and Foroud, T. and Quan, M. and Marek, K. and Siderowf, A. and others}, title = {{Biomarkers of neurodegeneration and glial activation validated in Alzheimer's disease assessed in longitudinal cerebrospinal fluid samples of Parkinson's disease}}, journal = {PloS one}, year = {2021}, doi = {10.1371/journal.pone.0257372}, pmid = {34618817}, url = {https://doi.org/10.1371/journal.pone.0257372} } @article{ewers2020-32790063, author = {Ewers, M. and Biechele, G. and Suárez-Calvet, M. and Sacher, C. and Blume, T. and Morenas-Rodriguez, E. and Deming, Y. and Piccio, L. and others}, title = {{Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation}}, journal = {EMBO molecular medicine}, year = {2020}, doi = {10.15252/emmm.202012308}, pmid = {32790063}, url = {https://doi.org/10.15252/emmm.202012308} } @article{leyns2019-31235932, author = {Leyns, C. E. G. and Gratuze, M. and Narasimhan, S. and Jain, N. and Koscal, L. J. and Jiang, H. and Manis, M. and Colonna, M. and others}, title = {{TREM2 function impedes tau seeding in neuritic plaques}}, journal = {Nature neuroscience}, year = {2019}, doi = {10.1038/s41593-019-0433-0}, pmid = {31235932}, url = {https://doi.org/10.1038/s41593-019-0433-0} } @article{nguyen2020-32840654, author = {Nguyen, A. T. and Wang, K. and Hu, G. and Wang, X. and Miao, Z. and Azevedo, J. A. and Suh, E. and Van Deerlin, V. M. and others}, title = {{APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer's disease}}, journal = {Acta neuropathologica}, year = {2020}, doi = {10.1007/s00401-020-02200-3}, pmid = {32840654}, url = {https://doi.org/10.1007/s00401-020-02200-3} } @article{kunkle2017-28738127, author = {Kunkle, B. W. and Vardarajan, B. N. and Naj, A. C. and Whitehead, P. L. and Rolati, S. and Slifer, S. and Carney, R. M. and Cuccaro, M. L. and others}, title = {{Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport}}, journal = {JAMA neurology}, year = {2017}, doi = {10.1001/jamaneurol.2017.1518}, pmid = {28738127}, url = {https://doi.org/10.1001/jamaneurol.2017.1518} } @article{bashore2024-38385291, author = {Bashore, A. C. and Yan, H. and Xue, C. and Zhu, L. Y. and Kim, E. and Mawson, T. and Coronel, J. and Chung, A. and others}, title = {{High-Dimensional Single-Cell Multimodal Landscape of Human Carotid Atherosclerosis}}, journal = {Arteriosclerosis, thrombosis, and vascular biology}, year = {2024}, doi = {10.1161/atvbaha.123.320524}, pmid = {38385291}, url = {https://doi.org/10.1161/atvbaha.123.320524} } @article{patel2019-30924900, author = {Patel, D. and Mez, J. and Vardarajan, B. N. and Staley, L. and Chung, J. and Zhang, X. and Farrell, J. J. and Rynkiewicz, M. J. and others}, title = {{Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry}}, journal = {JAMA network open}, year = {2019}, doi = {10.1001/jamanetworkopen.2019.1350}, pmid = {30924900}, url = {https://doi.org/10.1001/jamanetworkopen.2019.1350} } @article{ridge2016-27036079, author = {Ridge, P. G. and Hoyt, K. B. and Boehme, K. and Mukherjee, S. and Crane, P. K. and Haines, J. L. and Mayeux, R. and Farrer, L. A. and others}, title = {{Assessment of the genetic variance of late-onset Alzheimer's disease}}, journal = {Neurobiology of aging}, year = {2016}, doi = {10.1016/j.neurobiolaging.2016.02.024}, pmid = {27036079}, url = {https://doi.org/10.1016/j.neurobiolaging.2016.02.024} } @article{sayed2021-34851693, author = {Sayed, F. A. and Kodama, L. and Fan, L. and Carling, G. K. and Udeochu, J. C. and Le, D. and Li, Q. and Zhou, L. and others}, title = {{AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation}}, journal = {Science translational medicine}, year = {2021}, doi = {10.1126/scitranslmed.abe3947}, pmid = {34851693}, url = {https://doi.org/10.1126/scitranslmed.abe3947} } @article{prokop2019-31350575, author = {Prokop, S. and Miller, K. R. and Labra, SR. and Pitkin, R. M. and Hoxha, K. and Narasimhan, S. and Changolkar, L. and Rosenbloom, A. and others}, title = {{Impact of TREM2 risk variants on brain region-specific immune activation and plaque microenvironment in Alzheimer's disease patient brain samples}}, journal = {Acta neuropathologica}, year = {2019}, doi = {10.1007/s00401-019-02048-2}, pmid = {31350575}, url = {https://doi.org/10.1007/s00401-019-02048-2} } @article{suarezcalvet2018-30482868, author = {Suárez-Calvet, M. and Capell, A. and MÁ, Araque Caballero and Morenas-Rodríguez, E. and Fellerer, K. and Franzmeier, N. and Kleinberger, G. and Eren, E. and others}, title = {{CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline}}, journal = {EMBO molecular medicine}, year = {2018}, doi = {10.15252/emmm.201809712}, pmid = {30482868}, url = {https://doi.org/10.15252/emmm.201809712} } @article{nam2017-28655926, author = {Nam, K. N. and Mounier, A. and Wolfe, C. M. and Fitz, N. F. and Carter, A. Y. and Castranio, E. L. and Kamboh, H. I. and Reeves, V. L. and others}, title = {{Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer's model mice}}, journal = {Scientific reports}, year = {2017}, doi = {10.1038/s41598-017-04412-2}, pmid = {28655926}, url = {https://doi.org/10.1038/s41598-017-04412-2} } @article{castranio2017-28502803, author = {Castranio, E. L. and Mounier, A. and Wolfe, C. M. and Nam, K. N. and Fitz, N. F. and Letronne, F. and Schug, J. and Koldamova, R. and others}, title = {{Gene co-expression networks identify Trem2 and Tyrobp as major hubs in human APOE expressing mice following traumatic brain injury}}, journal = {Neurobiology of disease}, year = {2017}, doi = {10.1016/j.nbd.2017.05.006}, pmid = {28502803}, url = {https://doi.org/10.1016/j.nbd.2017.05.006} }