% alzhub.org library filter % Source: https://alzhub.org/research?category=genetics_trem2&institution=I2801533059 % 45 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{sims2017-28714976, author = {Sims, R. and van der Lee, S. J. and Naj, A. C. and Bellenguez, C. and Badarinarayan, N. and Jakobsdottir, J. and Kunkle, B. W. and Boland, A. and others}, title = {{Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease}}, journal = {Nature genetics}, year = {2017}, doi = {10.1038/ng.3916}, pmid = {28714976}, url = {https://doi.org/10.1038/ng.3916} } @article{lill2015-25936935, author = {Lill, C. M. and Rengmark, A. and Pihlstrøm, L. and Fogh, I. and Shatunov, A. and Sleiman, P. M. and Wang, L. S. and Liu, T. and others}, title = {{The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2015}, doi = {10.1016/j.jalz.2014.12.009}, pmid = {25936935}, url = {https://doi.org/10.1016/j.jalz.2014.12.009} } @article{parhizkar2019-30617257, author = {Parhizkar, S. and Arzberger, T. and Brendel, M. and Kleinberger, G. and Deussing, M. and Focke, C. and Nuscher, B. and Xiong, M. and others}, title = {{Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE}}, journal = {Nature neuroscience}, year = {2019}, doi = {10.1038/s41593-018-0296-9}, pmid = {30617257}, url = {https://doi.org/10.1038/s41593-018-0296-9} } @article{suarezcalvet2019-30630532, author = {Suárez-Calvet, M. and Morenas-Rodríguez, E. and Kleinberger, G. and Schlepckow, K. and MÁ, Araque Caballero and Franzmeier, N. and Capell, A. and Fellerer, K. and others}, title = {{Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-β pathology}}, journal = {Molecular neurodegeneration}, year = {2019}, doi = {10.1186/s13024-018-0301-5}, pmid = {30630532}, url = {https://doi.org/10.1186/s13024-018-0301-5} } @article{kleineidam2020-32166339, author = {Kleineidam, L. and Chouraki, V. and Próchnicki, T. and van der Lee, S. J. and Madrid-Márquez, L. and Wagner-Thelen, H. and Karaca, I. and Weinhold, L. and others}, title = {{PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment}}, journal = {Acta neuropathologica}, year = {2020}, doi = {10.1007/s00401-020-02138-6}, pmid = {32166339}, url = {https://doi.org/10.1007/s00401-020-02138-6} } @article{hooli2014-25186855, author = {Hooli, B. V. and Parrado, A. R. and Mullin, K. and Yip, W. K. and Liu, T. and Roehr, J. T. and Qiao, D. and Jessen, F. and others}, title = {{The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk}}, journal = {Neurology}, year = {2014}, doi = {10.1212/wnl.0000000000000855}, pmid = {25186855}, url = {https://doi.org/10.1212/wnl.0000000000000855} } @article{krasemann2017-28930663, author = {Krasemann, S. and Madore, C. and Cialic, R. and Baufeld, C. and Calcagno, N. and El Fatimy, R. and Beckers, L. and O'Loughlin, E. and others}, title = {{The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases}}, journal = {Immunity}, year = {2017}, doi = {10.1016/j.immuni.2017.08.008}, pmid = {28930663}, url = {https://doi.org/10.1016/j.immuni.2017.08.008} } @article{liu2018-30171911, author = {Liu, D. and Cao, B. and Zhao, Y. and Huang, H. and McIntyre, R. S. and Rosenblat, J. D. and Zhou, H.}, title = {{Soluble TREM2 changes during the clinical course of Alzheimer's disease: A meta-analysis}}, journal = {Neuroscience letters}, year = {2018}, doi = {10.1016/j.neulet.2018.08.038}, pmid = {30171911}, url = {https://doi.org/10.1016/j.neulet.2018.08.038} } @article{franzmeier2020-33032659, author = {Franzmeier, N. and Suárez-Calvet, M. and Frontzkowski, L. and Moore, A. and Hohman, T. J. and Morenas-Rodriguez, E. and Nuscher, B. and Shaw, L. and others}, title = {{Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration}}, journal = {Molecular neurodegeneration}, year = {2020}, doi = {10.1186/s13024-020-00407-2}, pmid = {33032659}, url = {https://doi.org/10.1186/s13024-020-00407-2} } @article{dalmasso2019-30705288, author = {Dalmasso, M. C. and Brusco, L. I. and Olivar, N. and Muchnik, C. and Hanses, C. and Milz, E. and Becker, J. and Heilmann-Heimbach, S. and others}, title = {{Transethnic meta-analysis of rare coding variants in PLCG2, ABI3, and TREM2 supports their general contribution to Alzheimer's disease}}, journal = {Translational psychiatry}, year = {2019}, doi = {10.1038/s41398-019-0394-9}, pmid = {30705288}, url = {https://doi.org/10.1038/s41398-019-0394-9} } @article{suarezcalvet2016-26941262, author = {Suárez-Calvet, M. and Kleinberger, G. and MÁ, Araque Caballero and Brendel, M. and Rominger, A. and Alcolea, D. and Fortea, J. and Lleó, A. and others}, title = {{sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers}}, journal = {EMBO molecular medicine}, year = {2016}, doi = {10.15252/emmm.201506123}, pmid = {26941262}, url = {https://doi.org/10.15252/emmm.201506123} } @article{ewers2020-32790063, author = {Ewers, M. and Biechele, G. and Suárez-Calvet, M. and Sacher, C. and Blume, T. and Morenas-Rodriguez, E. and Deming, Y. and Piccio, L. and others}, title = {{Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation}}, journal = {EMBO molecular medicine}, year = {2020}, doi = {10.15252/emmm.202012308}, pmid = {32790063}, url = {https://doi.org/10.15252/emmm.202012308} } @article{xiang2021-34644146, author = {Xiang, X. and Wind, K. and Wiedemann, T. and Blume, T. and Shi, Y. and Briel, N. and Beyer, L. and Biechele, G. and others}, title = {{Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases}}, journal = {Science translational medicine}, year = {2021}, doi = {10.1126/scitranslmed.abe5640}, pmid = {34644146}, url = {https://doi.org/10.1126/scitranslmed.abe5640} } @article{scheiblich2024-39059388, author = {Scheiblich, H. and Eikens, F. and Wischhof, L. and Opitz, S. and Jüngling, K. and Cserép, C. and Schmidt, S. V. and Lambertz, J. and others}, title = {{Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes}}, journal = {Neuron}, year = {2024}, doi = {10.1016/j.neuron.2024.06.029}, pmid = {39059388}, url = {https://doi.org/10.1016/j.neuron.2024.06.029} } @article{biel2023-36620941, author = {Biel, D. and Suárez-Calvet, M. and Hager, P. and Rubinski, A. and Dewenter, A. and Steward, A. and Roemer, S. and Ewers, M. and others}, title = {{sTREM2 is associated with amyloid-related p-tau increases and glucose hypermetabolism in Alzheimer's disease}}, journal = {EMBO molecular medicine}, year = {2023}, doi = {10.15252/emmm.202216987}, pmid = {36620941}, url = {https://doi.org/10.15252/emmm.202216987} } @article{safaiyan2021-33606969, author = {Safaiyan, S. and Besson-Girard, S. and Kaya, T. and Cantuti-Castelvetri, L. and Liu, L. and Ji, H. and Schifferer, M. and Gouna, G. and others}, title = {{White matter aging drives microglial diversity}}, journal = {Neuron}, year = {2021}, doi = {10.1016/j.neuron.2021.01.027}, pmid = {33606969}, url = {https://doi.org/10.1016/j.neuron.2021.01.027} } @article{vanlengerich2023-36635496, author = {van Lengerich, B. and Zhan, L. and Xia, D. and Chan, D. and Joy, D. and Park, J. I. and Tatarakis, D. and Calvert, M. and others}, title = {{A TREM2-activating antibody with a blood-brain barrier transport vehicle enhances microglial metabolism in Alzheimer's disease models}}, journal = {Nature neuroscience}, year = {2023}, doi = {10.1038/s41593-022-01240-0}, pmid = {36635496}, url = {https://doi.org/10.1038/s41593-022-01240-0} } @article{ma2018-30239611, author = {MÁ, Araque Caballero and Suárez-Calvet, M. and Duering, M. and Franzmeier, N. and Benzinger, T. and Fagan, A. M. and Bateman, R. J. and Jack, C. R. and others}, title = {{White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2018}, doi = {10.1093/brain/awy229}, pmid = {30239611}, url = {https://doi.org/10.1093/brain/awy229} } @article{brosseron2018-29482610, author = {Brosseron, F. and Traschütz, A. and Widmann, C. N. and Kummer, M. P. and Tacik, P. and Santarelli, F. and Jessen, F. and Heneka, M. T.}, title = {{Characterization and clinical use of inflammatory cerebrospinal fluid protein markers in Alzheimer's disease}}, journal = {Alzheimer's research \& therapy}, year = {2018}, doi = {10.1186/s13195-018-0353-3}, pmid = {29482610}, url = {https://doi.org/10.1186/s13195-018-0353-3} } @article{schlepckow2020-32154671, author = {Schlepckow, K. and Monroe, K. M. and Kleinberger, G. and Cantuti-Castelvetri, L. and Parhizkar, S. and Xia, D. and Willem, M. and Werner, G. and others}, title = {{Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region}}, journal = {EMBO molecular medicine}, year = {2020}, doi = {10.15252/emmm.201911227}, pmid = {32154671}, url = {https://doi.org/10.15252/emmm.201911227} } @article{gouna2021-34424266, author = {Gouna, G. and Klose, C. and Bosch-Queralt, M. and Liu, L. and Gokce, O. and Schifferer, M. and Cantuti-Castelvetri, L. and Simons, M.}, title = {{TREM2-dependent lipid droplet biogenesis in phagocytes is required for remyelination}}, journal = {The Journal of experimental medicine}, year = {2021}, doi = {10.1084/jem.20210227}, pmid = {34424266}, url = {https://doi.org/10.1084/jem.20210227} } @article{schlepckow2023-37863592, author = {Schlepckow, K. and Morenas-Rodríguez, E. and Hong, S. and Haass, C.}, title = {{Stimulation of TREM2 with agonistic antibodies-an emerging therapeutic option for Alzheimer's disease}}, journal = {The Lancet. 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G. and Schlepckow, K. and Morenas-Rodriguez, E. and others}, title = {{TREM2 protects from atherosclerosis by limiting necrotic core formation}}, journal = {Nature cardiovascular research}, year = {2024}, doi = {10.1038/s44161-024-00429-9}, pmid = {38974464}, url = {https://doi.org/10.1038/s44161-024-00429-9} } @article{brendel2017-28197095, author = {Brendel, M. and Kleinberger, G. and Probst, F. and Jaworska, A. and Overhoff, F. and Blume, T. and Albert, N. L. and Carlsen, J. and others}, title = {{Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis}}, journal = {Frontiers in aging neuroscience}, year = {2017}, doi = {10.3389/fnagi.2017.00008}, pmid = {28197095}, url = {https://doi.org/10.3389/fnagi.2017.00008} } @article{guner2020-32616437, author = {Güner, G. and Lichtenthaler, S. 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